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https://www.readbyqxmd.com/read/29333809/assessment-of-orofacial-pain-management-in-a-pediatric-emergency-department-and-at-home-after-discharge
#1
Yurena Aguilar de la Red, Gema Manrique Martín, Gloria Guerrero López, Concepción González Herrero, Paula López Vázquez, Concepción Míguez Navarro
INTRODUCTION: An inadequate pain management is common in the emergency department. Our objective was to analyze pain management among children with an orofacial infection or trauma in the emergency department and to assess compliance and satisfaction with analgesia prescribed at discharge. POPULATION AND METHODS: Cross-sectional, observational and analytical study in children attending the emergency department for an orofacial infection or trauma over 2 months. Pain management in the emergency department, analgesia prescribed at home and, following a call to parents, treatment provided and its adequacy to control pain were registered...
February 1, 2018: Archivos Argentinos de Pediatría
https://www.readbyqxmd.com/read/29332319/treatment-of-latent-tuberculosis-infection-and-its-clinical-efficacy
#2
REVIEW
Hyung Woo Kim, Ju Sang Kim
The role of the treatment for latent tuberculosis infection (LTBI) has been underscored in the intermediate tuberculosis (TB) burden countries like South Korea. LTBI treatment is recommended only for patients at risk for progression to active TB-those with frequent exposure to active TB cases, and those with clinical risk factors (e.g., immunocompromised patients). Recently revised National Institute for Health and Care Excellence (NICE) guideline recommended that close contacts of individuals with active pulmonary or laryngeal TB, aged between 18 and 65 years, should undergo LTBI treatment...
January 2018: Tuberculosis and Respiratory Diseases
https://www.readbyqxmd.com/read/29331170/implementation-lessons-learned-from-the-benefits-of-enhanced-terminal-room-betr-disinfection-study-process-and-perceptions-of-enhanced-disinfection-with-ultraviolet-disinfection-devices
#3
Deverick J Anderson, Lauren P Knelson, Rebekah W Moehring, Sarah S Lewis, David J Weber, Luke F Chen, Patricia F Triplett, Michael Blocker, R Marty Cooney, J Conrad Schwab, Yuliya Lokhnygina, William A Rutala, Daniel J Sexton
OBJECTIVE To summarize and discuss logistic and administrative challenges we encountered during the Benefits of Enhanced Terminal Room (BETR) Disinfection Study and lessons learned that are pertinent to future utilization of ultraviolet (UV) disinfection devices in other hospitals DESIGN Multicenter cluster randomized trial SETTING AND PARTICIPANTS Nine hospitals in the southeastern United States METHODS All participating hospitals developed systems to implement 4 different strategies for terminal room disinfection...
January 14, 2018: Infection Control and Hospital Epidemiology
https://www.readbyqxmd.com/read/29329561/strongyloides-stercoralis-and-hookworm-co-infection-spatial-distribution-and-determinants-in-preah-vihear-province-cambodia
#4
Armelle Forrer, Virak Khieu, Fabian Schär, Penelope Vounatsou, Frédérique Chammartin, Hanspeter Marti, Sinuon Muth, Peter Odermatt
BACKGROUND: Strongyloides stercoralis and hookworm are two soil-transmitted helminths (STH) that are highly prevalent in Cambodia. Strongyloides stercoralis causes long-lasting infections and significant morbidity but is largely neglected, while hookworm causes the highest public health burden among STH. The two parasites have the same infection route, i.e. skin penetration. The extent of co-distribution, which could result in potential high co-morbidities, is unknown in highly endemic settings like Cambodia...
January 12, 2018: Parasites & Vectors
https://www.readbyqxmd.com/read/29324651/incidence-microbiological-profile-and-risk-factors-of-healthcare-associated-infections-in-intensive-care-units-a-10-year-observation-in-a-provincial-hospital-in-southern-poland
#5
Małgorzata Kołpa, Marta Wałaszek, Agnieszka Gniadek, Zdzisław Wolak, Wiesław Dobroś
Healthcare-associated infections (HAIs) occurring in patients treated in an intensive care unit (ICU) are serious complications in the treatment process. Aetiological factors of these infections can have an impact on treatment effects, treatment duration and mortality. The aim of the study was to determine the prevalence and microbiological profile of HAIs in patients hospitalized in an ICU over a span of 10 years. The active surveillance method was used to detect HAIs in adult patients who spent over 48 h in a general ICU ward located in southern Poland between 2007 and 2016...
January 11, 2018: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29324238/immunization-with-recombinant-flid-confers-protection-against-helicobacter-pylori-infection-in-mice
#6
Amir Ghasemi, Nazanin Mohammad, Josef Mautner, Mehrnaz Taghipour Karsabet, Abolfazl Ardjmand, Rezvan Moniri
Nearly half of the world's population is infected with Helicobacter pylori. Clinical manifestations of this infection range from gastritis and peptic ulcers to gastric adenocarcinoma and lymphoma. Due to the emerging of antibiotic resistant strains and poor patient compliance of the antibiotic therapy, there is increasing interest in the development of a protective vaccine against H. pylori infection. The bacterial protein FliD forms a capping structure on the end of each flagellum which is critical to prevent depolymerization and structural degradation...
January 8, 2018: Molecular Immunology
https://www.readbyqxmd.com/read/29322103/a-national-survey-of-mri-safety-practices-in-ghana
#7
Albert Dayor Piersson, Philip Nii Gorleku
Objective: The aim of the present study was to assess current MRI safety practices among MRI facilities in Ghana, and their compliance with the 2013 American College of Radiology (ACR) guidance document on MR safe practices. Material and methods: A questionnaire developed from the 2013 ACR Guidance Document was used to collect information on magnetic field strengths, MR safety policy and compliance, patient screening, emergency preparedness, infection control, MRI safety accessories, equipment safety, signage and barriers, report of adverse incidents, and access and communication...
December 2017: Heliyon
https://www.readbyqxmd.com/read/29295754/diagnosis-and-therapeutic-approach-of-latent-tuberculosis-infection
#8
José Domínguez, Irene Latorre, Miguel Santin
Detection and treatment of latent tuberculosis infection (LTBI) is an essential measure for tuberculosis (TB) control in low-incidence countries. However, such strategy is limited by the low predictive ability of the diagnostic tests for the development of active TB among infected people and the long-term and toxic treatment regimens. The in vitro interferon-gamma release assays are more specific and sensitive than the tuberculin skin test (TST), and enable a better selection of cases requiring treatment. Nonetheless, their capacity to predict development of TB is still poor...
December 30, 2017: Enfermedades Infecciosas y Microbiología Clínica
https://www.readbyqxmd.com/read/29288706/improved-vaginal-retention-and-enhanced-antifungal-activity-of-miconazole-microsponges-gel-formulation-development-and-in-vivo-therapeutic-efficacy-in-rats
#9
Salwa Salah, Ghada E A Awad, Amal I A Makhlouf
Traditional azole antifungal formulations suffer from poor retention in the vaginal cavity, irritation and burning of the vaginal area. In the present work, we aim at the development of a novel miconazole (MCZ) microsponges gel as an attractive dosage form for vaginal candidiasis. The proposed formula has the potential to minimize the local side effects of the drug due to the controlled release characteristic, which increases patient compliance. Moreover, the mucosal retention effect of the microsponges in addition to the bioadhesion property of Carbopol gel prolongs the retention of the dosage form in the vagina and consequently improves the therapeutic efficiency...
December 27, 2017: European Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/29288095/microparticles-microcapsules-and-microspheres-a-review-of-recent-developments-and-prospects-for-oral-delivery-of-insulin
#10
REVIEW
Chun Y Wong, Hani Al-Salami, Crispin R Dass
Diabetes mellitus is a chronic metabolic health disease affecting the homeostasis of blood sugar levels. However, subcutaneous injection of insulin can lead to patient non-compliance, discomfort, pain and local infection. Sub-micron sized drug delivery systems have gained attention in oral delivery of insulin for diabetes treatment. In most of the recent literature, the terms "microparticles" and "nanoparticle" refer to particles where the dimensions of the particle are measured in micrometers and nanometers respectively...
December 26, 2017: International Journal of Pharmaceutics
https://www.readbyqxmd.com/read/29283367/surveillance-of-environmental-and-procedural-measures-of-infection-control-in-the-operating-theatre-setting
#11
Laura Dallolio, Alessandra Raggi, Tiziana Sanna, Magda Mazzetti, Alessandra Orsi, Angela Zanni, Patrizia Farruggia, Erica Leoni
The microbiological contamination of operating theatres and the lack of adherence to best practices by surgical staff represent some of the factors affecting Surgical Site Infections (SSIs). The aim of the present study was to assess the microbiological quality of operating settings and the staff compliance to the SSI evidence-based control measures. Ten operating rooms were examined for microbiological contamination of air and surfaces, after cleaning procedures, in "at rest" conditions. Furthermore, 10 surgical operations were monitored to assess staff compliance to the recommended practices...
December 28, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29248964/prevention-of-hospital-infections-by-intervention-and-training-prohibit-results-of-a-pan-european-cluster-randomized-multicentre-study-to-reduce-central-venous-catheter-related-bloodstream-infections
#12
Tjallie van der Kooi, Hugo Sax, Didier Pittet, Jaap van Dissel, Birgit van Benthem, Bernhard Walder, Vanessa Cartier, Lauren Clack, Sabine de Greeff, Martin Wolkewitz, Stefanie Hieke, Hendriek Boshuizen, Jan van de Kassteele, Annemie Van den Abeele, Teck Wee Boo, Magda Diab-Elschahawi, Uga Dumpis, Camelia Ghita, Susan FitzGerald, Tatjana Lejko, Kris Leleu, Mercedes Palomar Martinez, Olga Paniara, Márta Patyi, Paweł Schab, Annibale Raglio, Emese Szilágyi, Mirosław Ziętkiewicz, Albert W Wu, Hajo Grundmann, Walter Zingg
PURPOSE: To test the effectiveness of a central venous catheter (CVC) insertion strategy and a hand hygiene (HH) improvement strategy to prevent central venous catheter-related bloodstream infections (CRBSI) in European intensive care units (ICUs), measuring both process and outcome indicators. METHODS: Adult ICUs from 14 hospitals in 11 European countries participated in this stepped-wedge cluster randomised controlled multicentre intervention study. After a 6 month baseline, three hospitals were randomised to one of three interventions every quarter: (1) CVC insertion strategy (CVCi); (2) HH promotion strategy (HHi); and (3) both interventions combined (COMBi)...
December 16, 2017: Intensive Care Medicine
https://www.readbyqxmd.com/read/29235431/using-targeted-solution-tools-as-an-initiative-to-improve-hand-hygiene-challenges-and-lessons-learned
#13
J A Al-Tawfiq, M Treble, R Abdrabalnabi, C Okeahialam, S Khazindar, S Myers
The Joint Commission Centre for Transforming Healthcare's Web-based Targeted Solutions Tool (TST) for improving hand hygiene was implemented to elucidate contributing factors to low compliance rates of hand hygiene. Monitoring of compliance was done by trained unknown and known observers and rates of hospital-acquired infections were tracked and correlated against the changes in hand hygiene compliance. In total, 5669 of hand hygiene observations were recorded by the secret observers. The compliance rate increased from 75·4% at baseline (May-August 2014) to 88·6% during the intervention (13 months) and the control periods (P < 0·0001)...
December 13, 2017: Epidemiology and Infection
https://www.readbyqxmd.com/read/29221591/eradicating-bvd-reviewing-irish-programme-data-and-model-predictions-to-support-prospective-decision-making
#14
H-H Thulke, M Lange, J A Tratalos, T A Clegg, G McGrath, L O'Grady, P O'Sullivan, M L Doherty, D A Graham, S J More
Bovine Viral Diarrhoea is an infectious production disease of major importance in many cattle sectors of the world. The infection is predominantly transmitted by animal contact. Postnatal infections are transient, leading to immunologically protected cattle. However, for a certain window of pregnancy, in utero infection of the foetus results in persistently infected (PI) calves being the major risk of BVD spread, but also an efficient target for controlling the infection. There are two acknowledged strategies to identify PI animals for removal: tissue tag testing (direct; also known as the Swiss model) and serological screening (indirect by interpreting the serological status of the herd; the Scandinavian model)...
November 23, 2017: Preventive Veterinary Medicine
https://www.readbyqxmd.com/read/29221111/nasopharyngeal-carcinoma-risk-prediction-via-salivary-detection-of-host-and-epstein-barr-virus-genetic-variants
#15
Qian Cui, Fu-Tuo Feng, Miao Xu, Wen-Sheng Liu, You-Yuan Yao, Shang-Hang Xie, Xi-Zhao Li, Zu-Lu Ye, Qi-Sheng Feng, Li-Zhen Chen, Jin-Xin Bei, Lin Feng, Qi-Hong Huang, Wei-Hua Jia, Su-Mei Cao, Ellen T Chang, Weimin Ye, Hans-Olov Adami, Yi-Xin Zeng
Genetic susceptibility and Epstein-Barr virus (EBV) infection are important etiological factors in nasopharyngeal carcinoma (NPC). In this study, in southern China, where NPC is endemic, a single nucleotide polymorphism (SNP) in the EBV-encoded RPMS1 gene (locus 155391: G > A [G155391A]) and seven host SNPs (rs1412829, rs28421666, rs2860580, rs2894207, rs31489, rs6774494, and rs9510787) were confirmed to be significantly associated with NPC risk in 50 NPC cases versus 54 hospital-based controls with throat washing specimens and 1925 NPC cases versus 1947 hospital-based controls with buffy coat samples, respectively...
November 10, 2017: Oncotarget
https://www.readbyqxmd.com/read/29217101/a-novel-in-situ-simulation-intervention-used-to-mitigate-an-outbreak-of-methicillin-resistant-staphylococcus-aureus-in-a-neonatal-intensive-care-unit
#16
Kathleen Gibbs, Samuel DeMaria, Scarlett McKinsey, Andrea Fede, Anne Harrington, Deborah Hutchison, Carol Torchen, Adam Levine, Andrew Goldberg
OBJECTIVE: To describe the successful implementation of an in situ simulation program to diagnose and correct latent safety threats in a level 4 neonatal intensive care unit (NICU) to mitigate a methicillin-resistant Staphylococcus aureus (MRSA) outbreak. STUDY DESIGN: An investigational report describes a simulation intervention that occurred during a 4-month MRSA outbreak in a single-center, 46-bed, newly renovated level 4 NICU. The simulation program was developed for all NICU providers in which they were exposed to a 30-minute in situ human simulation intervention that included education, evaluation, and debriefing to resolve perceived or observed latent safety threats...
December 5, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/29215132/may-car-washing-represent-a-risk-for-legionella-infection
#17
T Baldovin, A Pierobon, C Bertoncello, E Destefani, M Gennari, A Stano, V Baldo
BACKGROUND: Legionella is a ubiquitous Gram-negative bacterium naturally found in aquatic environments. It can pose a health problem when it grows and spreads in man-made water systems. Legionella pneumophila is the most common cause of Legionnaires' disease nowadays, a community-acquired pneumonia with pulmonary symptoms and chest radiography no different from any other form of infectious pneumonia. Legionella monitoring is important for public health reasons, including the identification of unusual environmental sources of Legionella...
January 2018: Annali di Igiene: Medicina Preventiva e di Comunità
https://www.readbyqxmd.com/read/29211195/impact-of-two-bundles-on-central-catheter-related-bloodstream-infection-in-critically-ill-patients
#18
Cristobal Felipe Padilla Fortunatti
OBJECTIVE: To evaluate the impact of the implementation of insertion and maintenance bundles on the rates of catheter-related bloodstream infection in an intensive care unit. METHOD: This is a quasi-experimental, before-and-after study with a non-equivalent control group. During a six-month period, insertion and maintenance bundles for the central venous catheters were implemented. Supervision guidelines were developed to assess compliance with the bundle and catheter characteristics...
December 4, 2017: Revista Latino-americana de Enfermagem
https://www.readbyqxmd.com/read/29205275/antenatal-maternal-education-for-improving-postnatal-perineal-healing-for-women-who-have-birthed-in-a-hospital-setting
#19
REVIEW
Sonia M O'Kelly, Zena Eh Moore
BACKGROUND: The female perineum becomes suffused and stretched during pregnancy, and further strain during vaginal childbirth contributes to approximately 85% of women experiencing some degree of trauma to the perineal region. Multiple factors play a role in the type and severity of trauma experienced, including parity, delivery method, and local practices. There is ongoing debate about best midwifery practice to reduce perineal trauma. Once perineal trauma has occurred, treatment also varies greatly, depending on its degree and severity, local practice and customs, and personal preference...
December 4, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29198953/national-bundle-care-program-implementation-to-reduce-ventilator-associated-pneumonia-in-intensive-care-units-in-taiwan
#20
Chin-Chuan Kao, Hsiu-Tzy Chiang, Chih-Yu Chen, Ching-Tzu Hung, Ying-Chun Chen, Li-Hsiang Su, Zhi-Yuan Shi, Jein-Wei Liu, Chang-Pan Liu, Yin-Ching Chuang, Wen-Chien Ko, Yen-Hsu Chen, Shu-Hui Tseng, Chun-Ming Lee, Min-Chi Lu, Po-Ren Hsueh
BACKGROUND/PURPOSE: This study investigated the impact of implementing ventilator-associated pneumonia (VAP) bundle care on the rates of VAP in intensive care units (ICUs) in Taiwan. METHODS: A total of 10 ICUs (bed number, 170), including surgical (SICUs) (n = 7), cardiovascular/surgical (CV/S-ICUs) (n = 1), and medical ICUs (MICUs) (n = 2) from 10 hospitals (7 medical center hospitals and 3 regional hospitals) were enrolled in this quality-improvement project...
December 1, 2017: Journal of Microbiology, Immunology, and Infection, Wei Mian Yu Gan Ran za Zhi
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