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https://www.readbyqxmd.com/read/28712875/apical-constriction-in-distal-visceral-endoderm-cells-initiates-global-collective-cell-rearrangement-in-embryonic-visceral-endoderm-to-form-anterior-visceral-endoderm
#1
Go Shioi, Hideharu Hoshino, Takaya Abe, Hiroshi Kiyonari, Kazuki Nakao, Wenxiang Meng, Yasuhide Furuta, Toshihiko Fujimori, Shinichi Aizawa
The behavior of visceral endoderm cells was examined as the anterior visceral endoderm (AVE) formed from the distal visceral endoderm (DVE) using the mouse lines R26-H2B-EGFP and R26-PHA7-EGFP to visualize cell nuclei and adherens junction, respectively. The analysis using R26-H2B-EGFP demonstrated global cell rearrangement that was not specific to the DVE cells in the monolayer embryonic visceral endoderm sheet; each population of the endoderm cells moved collectively in a swirling movement as a whole. Most of the AVE cells at E6...
July 13, 2017: Developmental Biology
https://www.readbyqxmd.com/read/28690801/single-nucleotide-polymorphism-barcoding-of-cytochrome-c-oxidase-i-sequences-for-discriminating-17-species-of-columbidae-by-decision-tree-algorithm
#2
Cheng-Hong Yang, Kuo-Chuan Wu, Hans-Uwe Dahms, Li-Yeh Chuang, Hsueh-Wei Chang
DNA barcodes are widely used in taxonomy, systematics, species identification, food safety, and forensic science. Most of the conventional DNA barcode sequences contain the whole information of a given barcoding gene. Most of the sequence information does not vary and is uninformative for a given group of taxa within a monophylum. We suggest here a method that reduces the amount of noninformative nucleotides in a given barcoding sequence of a major taxon, like the prokaryotes, or eukaryotic animals, plants, or fungi...
July 2017: Ecology and Evolution
https://www.readbyqxmd.com/read/28687769/computational-sensing-of-herpes-simplex-virus-using-a-cost-effective-on-chip-microscope
#3
Aniruddha Ray, Mustafa Ugur Daloglu, Joslynn Ho, Avee Torres, Euan Mcleod, Aydogan Ozcan
Caused by the herpes simplex virus (HSV), herpes is a viral infection that is one of the most widespread diseases worldwide. Here we present a computational sensing technique for specific detection of HSV using both viral immuno-specificity and the physical size range of the viruses. This label-free approach involves a compact and cost-effective holographic on-chip microscope and a surface-functionalized glass substrate prepared to specifically capture the target viruses. To enhance the optical signatures of individual viruses and increase their signal-to-noise ratio, self-assembled polyethylene glycol based nanolenses are rapidly formed around each virus particle captured on the substrate using a portable interface...
July 7, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28682073/coupling-of-challenging-heteroaryl-halides-with-alkyl-halides-via-nickel-catalyzed-cross-electrophile-coupling
#4
Eric C Hansen, Changfeng Li, Sihang Yang, Dylan Pedro, Daniel J Weix
Despite their importance, the synthesis of alkylated heterocycles from the cross-coupling of Lewis basic nitrogen heteroaryl halides with alkyl halides remains a challenge. We report here a general solution to this challenge enabled by a new collection of ligands based around 2-pyridyl-N-cyanocarboxamidine and 2-pyridylcarboxamidine cores. Both primary and secondary alkyl halides can be coupled with 2-, 3-, and 4-pyridyl halides as well as other more complex heterocycles in generally good yields (41 examples, 69% ave yield)...
July 6, 2017: Journal of Organic Chemistry
https://www.readbyqxmd.com/read/28679778/combination-therapy-with-nhs-muil12-and-avelumab-anti-pd-l1-enhances-antitumor-efficacy-in-preclinical-cancer-models
#5
Chunxiao Xu, Yanping Zhang, P Alexander Rolfe, Vivian M Hernández, Wilson Guzman, Giorgio Kradjian, Bo Marelli, Guozhong Qin, Jin Qi, Hong Wang, Huakui Yu, Robert Tighe, Kin-Ming Lo, Jessie M English, Laszlo G Radvanyi, Yan Lan
To determine if combination therapy with NHS-muIL12 and the anti-PD-L1 antibody avelumab can enhance anti-tumor efficacy in preclinical models relative to monotherapies.<br /><br />Experimental Design: BALB/c mice bearing orthotopic EMT-6 mammary tumors and μMt(-) mice bearing subcutaneous MC38 tumors were treated with NHS-muIL12, avelumab, or combination therapy; tumor growth and survival were assessed. Tumor recurrence following remission and rechallenge was evaluated in EMT-6 tumor-bearing mice...
July 5, 2017: Clinical Cancer Research: An Official Journal of the American Association for Cancer Research
https://www.readbyqxmd.com/read/28679381/does-genetic-structure-reflect-differences-in-non-breeding-movements-a-case-study-in-small-highly-mobile-seabirds
#6
Petra Quillfeldt, Yoshan Moodley, Henri Weimerskirch, Yves Cherel, Karine Delord, Richard A Phillips, Joan Navarro, Luciano Calderón, Juan F Masello
BACKGROUND: In seabirds, the extent of population genetic and phylogeographic structure varies extensively among species. Genetic structure is lacking in some species, but present in others despite the absence of obvious physical barriers (landmarks), suggesting that other mechanisms restrict gene flow. It has been proposed that the extent of genetic structure in seabirds is best explained by relative overlap in non-breeding distributions of birds from different populations. We used results from the analysis of microsatellite DNA variation and geolocation (tracking) data to test this hypothesis...
July 5, 2017: BMC Evolutionary Biology
https://www.readbyqxmd.com/read/28668667/factors-influencing-codon-usage-of-mitochondrial-nd1-gene-in-pisces-aves-and-mammals
#7
Arif Uddin, Monisha Nath Choudhury, Supriyo Chakraborty
Animal mitochondrial genome harbours 13 protein coding genes which regulate the process of respiration. The mitochondrial NADH dehydrogenase 1 (MT-ND1) gene, one of the 13 protein-coding genes, encodes the NADH dehydrogenase 1 enzyme of the respiratory chain. Analysis of codon usage bias (CUB) acquires importance for better understanding of the molecular biology, new gene discovery, design of transgenes and gene evolution. The MT-ND1 gene seems to be a good candidate for analyzing codon usage pattern, since no work has yet been reported...
June 28, 2017: Mitochondrion
https://www.readbyqxmd.com/read/28660691/metagenomic-analysis-of-the-complex-microbial-consortium-associated-with-cultures-of-the-oil-rich-alga-botryococcus-braunii
#8
Christine Sambles, Karen Moore, Thomas M Lux, Katy Jones, George R Littlejohn, João D Gouveia, Stephen J Aves, David J Studholme, Rob Lee, John Love
Microalgae are widely viewed as a promising and sustainable source of renewable chemicals and biofuels. Botryococcus braunii synthesizes and secretes significant amounts of long-chain (C30 -C40 ) hydrocarbons that can be subsequently converted into gasoline, diesel, and aviation fuel. B. braunii cultures are not axenic and the effects of co-cultured microorganisms on B. braunii growth and hydrocarbon yield are important, but sometimes contradictory. To understand the composition of the B. braunii microbial consortium, we used high throughput Illumina sequencing of metagenomic DNA to profile the microbiota within a well established, stable B...
June 28, 2017: MicrobiologyOpen
https://www.readbyqxmd.com/read/28651888/how-can-lifeguards-recover-better-a-cross-over-study-comparing-resting-running-and-foam-rolling
#9
Antón Kalén, Alexandra Pérez-Ferreirós, Roberto Barcala-Furelos, María Fernández-Méndez, Alexis Padrón-Cabo, Jose-Antonio Prieto, Andrés Ríos-Ave, Cristian Abelairas-Gómez
PURPOSE: The aim of this study is to compare the effectiveness of active recovery in form of running or foam rolling on clearing blood lactate compared to remain sitting after a water rescue. METHOD: A quasi experimental cross-over design was used to test the effectiveness of two active recovery methods: foam rolling (FR) and running (RR), compared with passive recovery (PR) on the blood lactate clearance after performing a water rescue. Twelve lifeguards from Marín (Pontevedra) completed the study...
June 15, 2017: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28638421/item-selection-and-content-validity-of-the-risk-factors-of-post-intubation-tracheal-stenosis-observation-questionnaire-for-icu-admitted-patients
#10
Roya Farzanegan, Behrooz Farzanegan, Maryam Alehashem, Mahdi Zangi, Sharareh R Niakan Kalhori, Kambiz Sheikhy, Habib Emami, Mohammad Behgam Shadmehr
BACKGROUND: Laryngotracheal stenosis as a late complication of prolonged endotracheal intubation is a life-threatening event. In order to determine the related risk factors for this complication, which may vary among different countries, designing a valid questionnaire is necessary. The aim of this study was to select the items and evaluate the face and content validities of a questionnaire developed for assessment of risk factors of post-intubation tracheal stenosis (PITS) in patients admitted in the intensive care unit...
2017: Tanaffos
https://www.readbyqxmd.com/read/28635188/the-financial-and-quality-of-life-cost-to-patients-living-with-a-chronic-wound-in-the-community
#11
Suzanne Kapp, Nick Santamaria
Chronic wounds are associated with financial and personal costs. The system level expense associated with chronic wounds has been established, however, the out-of-pocket cost incurred by individuals who self-fund has not been the focus of extensive investigation. Recently, there has been renewed interest in evaluating quality of life, in line with the shift to patient enablement and self-care in chronic disease management. The objectives of this research were to describe the out-of-pocket wound treatment costs and the quality of life of people who have chronic wounds...
June 20, 2017: International Wound Journal
https://www.readbyqxmd.com/read/28620590/functional-redundancy-and-ecological-innovation-shape-the-circulation-of-tick-transmitted-pathogens
#12
Agustín Estrada-Peña, José de la Fuente, Alejandro Cabezas-Cruz
Ticks are vectors of pathogens affecting human and animal health worldwide. Nevertheless, the ecological and evolutionary interactions between ticks, hosts, and pathogens are largely unknown. Here, we integrated a framework to evaluate the associations of the tick Ixodes ricinus with its hosts and environmental niches that impact pathogen circulation. The analysis of tick-hosts association suggested that mammals and lizards were the ancestral hosts of this tick species, and that a leap to Aves occurred around 120 M years ago...
2017: Frontiers in Cellular and Infection Microbiology
https://www.readbyqxmd.com/read/28620278/revealing-the-dysfunction-of-schematic-facial-expression-processing-in-schizophrenia-a-comparative-study-of-different-references
#13
Shenglin She, Haijing Li, Yuping Ning, Jianjuan Ren, Zhangying Wu, Rongcheng Huang, Jingping Zhao, Qian Wang, Yingjun Zheng
The use of event-related potential (ERP) recording technology during perceptual and cognitive processing has been studied in order to develop objective diagnostic indexes for people with neuropsychiatric disorders. For example, patients with schizophrenia exhibit consistent abnormalities in face-evoked early components of ERPs and mismatch negativities (MMNs). In most studies, the choice of reference has been the average reference (AVE), but whether this is the most suitable choice is still unknown. The aim of this study was to systematically compare the AVE and reference electrode standardization technique (REST) methods for assessing expressional face-evoked early visual ERPs and visual MMNs (vMMNs) in patients with schizophrenia and healthy controls...
2017: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/28615067/correspondence-on-lovell-et-al-identification-of-chicken-genes-previously-assumed-to-be-evolutionarily-lost
#14
Susanne Bornelöv, Eyal Seroussi, Sara Yosefi, Ken Pendavis, Shane C Burgess, Manfred Grabherr, Miriam Friedman-Einat, Leif Andersson
Through RNA-Seq analyses, we identified 137 genes that are missing in chicken, including the long-sought-after nephrin and tumor necrosis factor genes. These genes tended to cluster in GC-rich regions that have poor coverage in genome sequence databases. Hence, the occurrence of syntenic groups of vertebrate genes that have not been observed in Aves does not prove the evolutionary loss of such genes.Please see related Research article: http://dx.doi.org/10.1186/s13059-014-0565-1 and Please see response from Lovell et al: https://www...
June 14, 2017: Genome Biology
https://www.readbyqxmd.com/read/28610380/a-cryptic-new-species-of-hummingbird-of-the-campylopterus-largipennis-complex-aves-trochilidae
#15
Leonardo Esteves Lopes, Marcelo Ferreira DE Vasconcelos, Luiz Pedreira Gonzaga
A new species of Campylopterus sabrewing is described from eastern Brazilian tropical dry forests occurring below 900 m asl. Its holotype (MZUSP 99024) is an adult female from Sítio Duboca (16°43'19''S, 43°58'20''W, elevation 840 m), municipality of Montes Claros, state of Minas Gerais. A taxonomic revision based on more than 1,000 museum specimens revealed that the new taxon, together with C. largipennis, C. diamantinensis and C. obscurus (with C. aequatorialis considered as a subjective junior synonym) should be ranked as species...
May 15, 2017: Zootaxa
https://www.readbyqxmd.com/read/28610325/a-brief-history-of-the-generic-classification-of-the-trochilini-aves-trochilidae-the-chaos-of-the-past-and-problems-to-be-resolved
#16
F Gary Stiles, Vitor DE Q Piacentini, J V Remsen
The generic classification of the Trochilidae is unusually complicated because early authors, faced with a deluge of specimens with little or no data, often based species and genus names on superficial plumage characters derived from figured plates of varying artistic quality and reproduction. Working independently and with little knowledge of species distributions and with the fixation of type species for genera inconsistent or ignored, these authors produced a bewildering array of generic synonyms. The generic nomenclature of the largest and most recently derived clade of hummingbirds, the tribe Trochilini or "emeralds", presents an unusually tangled web...
May 23, 2017: Zootaxa
https://www.readbyqxmd.com/read/28610269/feather-mites-of-the-genera-i-dubininia-i-and-i-cacatualges-i-acari-xolalgidae-associated-with-parrots-aves-psittaciformes-of-the-old-world
#17
Sergey V Mironov, Rainer Ehrnsberger, Jacek Dabert
This paper gives a systematic revision of feather mites of the genera Dubininia Vassilev, 1958 and Cacatualges Dabert, Badek and Skoracki, 2007 (Xolalgidae: Ingrassiinae) associated with parrots (Aves: Psittaciformes) of the Old World. Five new species are described: Cacatualges probosciger sp. n. from Probosciger aterrimus (Gmelin) (Cacatuidae) from New Guinea, Dubininia charmosynae sp. n. from Charmosyna pulchella Gray GR (Psittaculidae) from New Guinea, D. micropsittae sp. n. from Micropsitta pusio pusio (Scaltter) (Psittaculidae) from New Guinea, D...
May 31, 2017: Zootaxa
https://www.readbyqxmd.com/read/28610213/a-new-genus-for-the-blue-and-yellow-tanager-aves-passeriformes-%C3%A2-a-suggested-adjustment-to-the-classification-of-the-thraupidae
#18
Vítor DE Q Piacentini
Recent DNA-based studies have found that the genus Thraupis, as traditionally defined, is polyphyletic, with the Blue-and-yellow Tanager (historically treated as Thraupis bonariensis) being sister to the Fawn-breasted Tanager (Pipraeidea melanonota). As a result, most subsequent classifications lumped both species under a single genus, Pipraeidea. Here I show that both species differ markedly in plumage, morphology, voice, and behavior, each of them being more similar to a distantly related species than to each other...
June 11, 2017: Zootaxa
https://www.readbyqxmd.com/read/28610087/clarification-of-the-type-locality-of-the-curl-crested-aracari-i-pteroglossus-beauharnaesii-i-wagler-1832-aves-ramphastidae
#19
Thiago V V Costa, José Fernando Pacheco, Luís Fábio Silveira
The Curl-crested Aracari Pteroglossus beauharnaesii Wagler, 1832 is one of the most remarkable species in the family Ramphastidae. Among other distinctive plumage traits, its modified curly, shiny black crown feathers are unique in the family and are modified to an extent not found in any other living bird species (Brush 1967; Short & Horne 2002). The crown feathers, along with the distinct white throat, were considered sufficient justification in the past to include the species in the monotypic genus Beauharnaisius Bonaparte; however, molecular studies have shown that it is embedded within the genus Pteroglossus Illiger, sister to P...
March 23, 2017: Zootaxa
https://www.readbyqxmd.com/read/28610029/type-specimens-and-type-localities-of-birds-aves-collected-during-f-j-f-meyen-s-circumnavigation-in-1830-1832
#20
Jiří Mlíkovský, Sylke Frahnert
At least 32 bird species were described as new to science on the basis of material collected by Franz Meyen during his circumnavigation in 1830-1832. We identified the type specimens and determined the type localities of these species, which are currently housed in the Museum für Naturkunde, Berlin, Germany. Ardea longicollis Meyen, 1834, is identified as a senior synonym of Egretta eulophotes (Swinhoe, 1860), but is set aside as a nomen oblitum. The name of a Neotropical dove is corrected from Metriopelia ceciliae zimmeri (Peters, 1937) to Metriopelia ceciliae gymnops (Chubb, 1917)...
April 3, 2017: Zootaxa
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