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endomyocardial fibrosis

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https://www.readbyqxmd.com/read/28090258/echocardiographic-and-histologic-correlations-in-patients-with-severe-aortic-stenosis-influence-of-overweight-and-obesity
#1
Nydia Ávila-Vanzzini, Juan Francisco Fritche-Salazar, Nelva Marina Vázquez-Castro, Pedro Rivera-Lara, Oscar Pérez-Méndez, Humberto Martínez-Herrera, Mario Gómez-Sánchez, Alberto Aranda-Frausto, Héctor Herrera-Bello, María Luna-Luna, José Antonio Arias Godínez
BACKGROUND: Severe aortic stenosis (AS), leads to pathological left ventricular remodeling that may worsen with concomitant overweight and obesity (OW/O). METHODS: We aimed to prospectively analyze the impact of OW/O on ventricular remodeling in severe AS, by evaluating the percentage of intraendomyocardial fibrosis (PIEF) and the percentage of infiltrating intraendocardial lipid vacuoles (PIELV) and its relationship to global longitudinal strain (GLS) in patients with OW/O...
December 2016: Journal of Cardiovascular Ultrasound
https://www.readbyqxmd.com/read/28072629/the-key-clues-to-reach-the-diagnosis-of-loeffler-endomyocardial-fibrosis-associated-with-eosinophilic-granulomatosis-with-polyangiitis
#2
Enrico Ammirati, Domenico Sirico, Linda Brevetti, Laura Scudiero, Diana Artioli, Patrizia Pedrotti, Maria Frigerio
Loeffler endomyocardial fibrosis is a rare restrictive cardiomyopathy due to chronic eosinophilic exposure (Loeffler endomyocarditis). Loeffler endomyocarditis is associated with different eosinophilic disorders, including eosinophilic granulomatosis with polyangiitis (EGPA). These images recapitulate all typical findings that can be observed in patients presenting with heart failure attributable to this specific cardiomyopathy associated with EGPA, a systemic medical condition that can be easily detectable just putting together different diagnostic elements...
January 7, 2017: Journal of Cardiovascular Medicine
https://www.readbyqxmd.com/read/28068787/ventricular-endomyocardial-fibrosis-in-a-pregnant-female-with-beh%C3%A3-et-s-disease
#3
Zahra Mirfeizi, Bahram Memar, Hoorak PourZand, Mohammad Hadi Molseghi, Arash Rezaei Shahmirzadi, Nafiseh Abdolahi
A 32-year-old pregnant woman, diagnosed with Behçet's disease 6 months earlier, presented with recent mild hemoptysis and exertional dyspnea. Transthoracic echocardiography showed an enlarged dysfunctional right ventricle. A large hypoechoic triangular-shaped mass was seen attached to the inner right ventricular wall, filling the cavity. No change in the size of the mass was noted after anticoagulant administration, and right heart failure progressed. Surgery was performed to remove the mass and repair the tricuspid valve...
January 1, 2017: Asian Cardiovascular & Thoracic Annals
https://www.readbyqxmd.com/read/28050425/severe-left-ventricular-endomyocardial-fibrosis-presenting-as-biventricular-failure-in-a-young-adult-a-case-report
#4
Harpreet Singh Sandhu, Sampathkumar Mahadevappa Mahendrakar, Rajebali Ramzanali Pethani, Azizullah Hafizullah Khan, Yunus Shafi Loya
Endomyocardial Fibrosis (EMF) is a form of progressive restrictive cardiomyopathy of unclear aetiology prevalent in areas within 15(0) of equator including coastal areas of Kerala a few decades back. It inflicts young adults and carries a poor prognosis due to limited options for treatment. Fortunately, the incidence of cases is now declining due to improvement in health and hygiene standards. Here, we review the aetiology and pathogenesis of EMF and report a case of a young male from Mumbai (non-endemic area) presenting with progressively worsening breathlessness and signs of heart failure unresponsive to conventional medical treatment...
November 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28031230/rare-association-of-endomyocardial-fibrosis-and-chagas-heart-disease
#5
Viviane Tiemi Hotta, Bárbara Maria Ianni, Antonildes Nascimento Assunção, José Rodrigues Parga, Charles Mady
No abstract text is available yet for this article.
December 27, 2016: European Heart Journal Cardiovascular Imaging
https://www.readbyqxmd.com/read/28004175/left-ventricular-reverse-remodeling-is-not-related-to-biopsy-detected-extracellular-matrix-fibrosis-and-serum-markers-of-fibrosis-in-dilated-cardiomyopathy-regardless-of-the-definition-used-for-lvrr
#6
Paweł Rubiś, Sylwia Wiśniowska-Śmiałek, Barbara Biernacka-Fijałkowska, Lucyna Rudnicka-Sosin, Ewa Wypasek, Artur Kozanecki, Ewa Dziewięcka, Patrycja Faltyn, Aleksandra Karabinowska, Lusine Khachatryan, Marta Hlawaty, Agata Leśniak-Sobelga, Magdalena Kostkiewicz, Wojciech Płazak, Piotr Podolec
Left ventricular reverse remodeling (LVRR) is reported in dilated cardiomyopathy (DCM) patients (pts). However, numerous definitions of LVRR exist. Measurements of serum markers of fibrosis provide insight into myocardial fibrosis. The relationship between LVRR and fibrosis is poorly understood. From July 2014 until October 2015, we included 63 consecutive DCM pts (48 ± 12.1 years, EF 24.4 ± 7.4%) with completed baseline and 3-month follow-up echocardiograms. LVRR was assessed on the basis of four differing definitions...
December 21, 2016: Heart and Vessels
https://www.readbyqxmd.com/read/27981817/intracardiac-thrombus-in-beh%C3%A3-et-s-disease
#7
I Ben Ghorbel, N Belfeki, M H Houman
Behçet's disease (BD) is a multisystem inflammatory disorder. Intracardiac thrombus (ICT) formation is an uncommon but important complication of BD. Of the cases of Behçet's disease, we selected those with ICT. All patients fulfilled the diagnostic criteria of the International Study Group of Behçet's disease. The ICT in each case was confirmed by ultrasonography, computed tomography and MRI. Clinical features and laboratory parameters were determined. Among our 518 patients with BD, 8 were diagnosed as having intracardiac thrombus (ICT)...
December 16, 2016: Reumatismo
https://www.readbyqxmd.com/read/27931613/later-onset-fabry-disease-cardiac-damage-progress-in-silence-experience-with-a-highly-prevalent-mutation
#8
Ting-Rong Hsu, Sheng-Che Hung, Fu-Pang Chang, Wen-Chung Yu, Shih-Hsien Sung, Chia-Lin Hsu, Ivan Dzhagalov, Chia-Feng Yang, Tzu-Hung Chu, Han-Jui Lee, Yung-Hsiu Lu, Sheng-Kai Chang, Hsuan-Chieh Liao, Hsiang-Yu Lin, Tsan-Chieh Liao, Pi-Chang Lee, Hsing-Yuan Li, An-Hang Yang, Hui-Chen Ho, Chuan-Chi Chiang, Ching-Yuang Lin, Robert J Desnick, Dau-Ming Niu
BACKGROUND: Recently, several studies revealed a much higher prevalence of later onset Fabry disease (FD) than previously expected. It suggested that later onset FD might present as an important hidden health issue in certain ethnic or demographic populations in the world. However, the natural history of its phenotype has not been systemically investigated, especially the cardiac involvement. OBJECTIVES: The study analyzed a large-scale newborn screening program for FD to understand the natural course of later onset FD...
December 13, 2016: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/27930686/comparison-of-ventricular-inducibility-with-late-gadolinium-enhancement-and-myocardial-inflammation-in-endomyocardial-biopsy-in-patients-with-dilated-cardiomyopathy
#9
Karin A L Mueller, Christian Heck, David Heinzmann, Johannes Schwille, Karin Klingel, Reinhard Kandolf, Ulrich Kramer, Michael Gramlich, Tobias Geisler, Meinrad P Gawaz, Juergen Schreieck, Peter Seizer
BACKGROUND: Risk stratification of patients with non-ischemic dilated cardiomyopathy remains a matter of debate in the era of device implantation. OBJECTIVE: We investigated associations between histopathological findings, contrast-enhanced cardiac MRI and the inducibility of ventricular tachycardia (VT) or fibrillation (VF) in programmed ventricular stimulation. METHODS: 56 patients with impaired left ventricular ejection fraction (LVEF≤50%, mean 36...
2016: PloS One
https://www.readbyqxmd.com/read/27904843/cardiac-surgery-in-africa-a-thirty-five-year-experience-on-open-heart-surgery-in-cote-d-ivoire
#10
Koffi Herve Yangni-Angate, Christophe Meneas, Florent Diby, Manga Diomande, Anicet Adoubi, Yves Tanauh
BACKGROUND: Few centers for open heart surgery (OHS) are in Sub-Saharan Africa. Lack of OHS results is also noted. By reporting our African experience on OHS, the aim of this study was to fill the gap. METHODS: It is a retrospective study on 2,612 patients who were subject to an OHS between 1978 and 2013. Data were collected from demographical, clinical, investigative studies, surgical and outcomes parameters. RESULTS: There were 1,475 cases of rheumatic heart diseases (RHD), 126 endomyocardial fibrosis (EMF), 741 congenital heart diseases (CHDs) and 270 various affections...
October 2016: Cardiovascular Diagnosis and Therapy
https://www.readbyqxmd.com/read/27886792/diagnosis-and-management-of-endomyocardial-fibrosis
#11
REVIEW
Andrea Beaton, Ana Olga Mocumbi
Endomyocardial fibrosis (EMF) remains an important cause of restrictive cardiomyopathy worldwide. Patients cluster in specific geographic locations and are almost universally living in extreme poverty. Specific etiology remains elusive and is likely multifactorial. Untreated EMF has a very poor prognosis. Medical management can mitigate symptoms for a time but has no curative benefit. Early surgical interventions may improve survival but are not readily available in most EMF-endemic regions. Increased awareness, advocacy, and research are needed to further understand this neglected tropical cardiomyopathy and to improve survival of those affected...
February 2017: Cardiology Clinics
https://www.readbyqxmd.com/read/27867529/coexistence-of-apical-hypertrophic-cardiomyopathy-and-endomyocardial-fibrosis-with-calcification-diagnosis-using-multimodality-imaging
#12
Lakshmi Muthukumar, M Fuad Jan, Joseph Whitnah, A Jamil Tajik
A 48-year-old man from West Africa was evaluated for dyspnea. Echocardiography showed an echolucent mass at the left ventricular apex surrounded by a dense ridge of tissue, suggesting endomyocardial fibrosis (EMF). Doppler echocardiography showed restrictive hemodynamics and intramyocardial coronary blood flow at the hypertrophied apex, suggesting apical hypertrophic cardiomyopathy (ApHCM) with calcified thrombus. Cardiac magnetic resonance imaging showed a thickened myocardium with apical cavity obliteration and endomyocardial calcification, and gadolinium contrast demonstrated marked bright subendocardial and diffuse patchy intramyocardial hyperenhancement in the hypertrophied apical wall segment, confirming coexistence of EMF and ApHCM...
December 2016: ESC Heart Failure
https://www.readbyqxmd.com/read/27867457/a-heart-set-in-stone-a-case-of-extensive-cardiac-calcification
#13
Roopali Khanna, Aditya Kapoor, Neetu Soni
Massive endocardial calcification is a rare entity. We describe a rare disease endomyocardial fibrosis associated with massive calcification of the left ventricle suspected on a chest X-ray and confirmed by echocardiography and computed tomography in an 18-year-old female presenting with breathlessness and congestive heart failure.
July 2016: Heart Views: the Official Journal of the Gulf Heart Association
https://www.readbyqxmd.com/read/27812527/a-novel-murine-model-of-parvovirus-associated-dilated-cardiomyopathy-induced-by-immunization-with-vp1-unique-region-of-parvovirus-b19
#14
Julijus Bogomolovas, Egidijus Šimoliūnas, Ieva Rinkūnaitė, Luka Smalinskaitė, Andrej Podkopajev, Daiva Bironaitė, Cleo-Aron Weis, Alexander Marx, Virginija Bukelskienė, Norbert Gretz, Virginija Grabauskienė, Dittmar Labeit, Siegfried Labeit
Background. Parvovirus B19 (B19V) is a common finding in endomyocardial biopsy specimens from myocarditis and dilated cardiomyopathy patients. However, current understanding of how B19V is contributing to cardiac damage is rather limited due to the lack of appropriate mice models. In this work we demonstrate that immunization of BALB/c mice with the major immunogenic determinant of B19V located in the unique sequence of capsid protein VP1 (VP1u) is an adequate model to study B19V associated heart damage. Methods and Results...
2016: BioMed Research International
https://www.readbyqxmd.com/read/27805245/active-schistosomiasis-severe-hypereosinophilia-and-rapid-progression-of-chronic-endomyocardial-fibrosis
#15
A O Mocumbi, C Goncalves, A Damasceno, C Carrilho
Endomyocardial fibrosis (EMF) is a neglected restrictive cardiomyopathy of unknown aetiology and unclear natural history, which causes premature deaths in endemic areas. We present the case of a 13-year-old boy from a highly endemic area, presenting with concurrent signs of chronic EMF and severe hypereosinophilia associated with active schistosomal cystitis. We discuss the possible role of this parasitic infection in determining the progression of EMF in endemic areas for both conditions.
October 23, 2016: Cardiovascular Journal of Africa
https://www.readbyqxmd.com/read/27800525/staphylococcus-aureus-endocarditis-as-a-complication-of-toxocariasis-associated-endomyocarditis-with-fibrosis-a-case-report
#16
Esther Kuenzli, Niklaus Labhardt, Gianmarco Balestra, Maja Weisser, Michael J Zellweger, Johannes Blum
Complications associated with Toxocara canis infection are rare. We present a case of a patient with Staphylococcus aureus endocarditis as a complication of an endomyocardial fibrosis caused by T canis. The epidemiological, pathological, and clinical features of this rare complication are described here.
September 2016: Open Forum Infectious Diseases
https://www.readbyqxmd.com/read/27751343/endomyocardial-fibrosis-with-right-ventricular-aneurysm-mimicking-arvc-a-case-report-from-india
#17
Suneesh Kalliath, Rajesh Gopalan Nair, Haridasan Vellani
A 48-year-old man presented with chronic right sided heart failure. 2D echocardiography revealed the classical features of left ventricular endomyocardial fibrosis with a prominent right ventricular apical aneurysm. Right ventriculography further defined the aneurysm. Cardiac magnetic resonance images revealed a thin-walled, apical aneurysm of right ventricle with multiple septations and marked obliteration of left ventricular apex. A delayed-enhancement sequence after the infusion of contrast, demonstrated a hypersignal in the subendocardium, consistent with the right ventricular involvement of endomyocardial fibrosis...
September 2016: Indian Heart Journal
https://www.readbyqxmd.com/read/27751288/bundle-branch-reentry-a-rare-mechanism-of-ventricular-tachycardia-in-endomyocardial-fibrosis-without-ventricular-dilation
#18
Mukund A Prabhu, B V Srinivas Prasad, Anees Thajudeen, Narayanan Namboodiri
INTRODUCTION: Bundle branch reentry as a mechanism of ventricular tachycardia (VT) in endomyocardial fibrosis (EMF) is not described. CASE REPORT: A 52-year-old woman with left ventricular (LV) EMF had VT needing cardioversion. She had mitral regurgitation and left bundle branch block, but no LV dilation or heart failure. During electrophysiological study, clinical VT could be easily induced, and it was confirmed to be bundle branch reentrant VT (BBRVT). She was treated with ablation of the right bundle branch...
September 2016: Indian Heart Journal
https://www.readbyqxmd.com/read/27751283/dystrophic-myocardial-calcification
#19
Rajiv Ananthakrishna, Nagaraja Moorthy
Myocardial calcification is rare and occurs in previous myocardial infarction, endomyocardial fibrosis, and infections such as tuberculosis, chronic renal failure, or hyperparathyroidism. We present an interesting case of massive myocardial calcification of the left ventricle following prior extensive myocardial infarction, presenting as progressive heart failure.
September 2016: Indian Heart Journal
https://www.readbyqxmd.com/read/27751273/doughnut-appearance-of-left-ventricle-in-isolated-left-ventricular-endomyocardial-fibrosis
#20
Mahim Saran, Sivasankaran Sivasubramonian
A 55-year-old female presented with worsening dyspnea secondary to left ventricular endomyocardial fibrosis (EMF). Obliteration of left ventricular apex and hypertrophied papillary muscle gave the classical appearance of a "doughnut" on left ventricular angiography. We present here a novel doughnut appearance of left ventricle on angiogram.
September 2016: Indian Heart Journal
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