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Helicobacter eradication

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https://www.readbyqxmd.com/read/29691237/eradicating-h-pylori-reduces-gastric-cancer-risk
#1
(no author information available yet)
Eliminating the bacterial infection Helicobacter pylori in patients with early gastric cancer may reduce the risk of metachronous disease. In a recent study, eradicating the infection reduced patients' risk of developing a subsequent gastric cancer by almost 50% and, in nearly half of patients, decreased the severity of atrophic gastritis.
April 24, 2018: Cancer Discovery
https://www.readbyqxmd.com/read/29690823/the-need-for-a-patient-tailored-helicobacter-pylori-eradication-protocol-prior-to-bariatric-surgery
#2
Tadeja Pintar, Niko Kaliterna, Tanja Carli
Objective High-quality data indicating the advantages of preoperative Helicobacter pylori screening and eradication as well the clinical outcomes of patients with and without H. pylori after bariatric surgery are lacking. Methods In total, 96 morbidly obese patients with H. pylori preparing for bariatric surgery were retrospectively reviewed. Results Of 96 biopsy specimens, 73 (76%) were positive for H. pylori on initial Giemsa staining. These patients were treated with the standard 7-day antibiotic treatment protocol corrected by the individual patient's creatinine clearance rate and body mass index and received a 30% higher dose because of their H...
January 1, 2018: Journal of International Medical Research
https://www.readbyqxmd.com/read/29686466/nutrition-status-and-helicobacter-pylori-infection-in-patients-receiving-hemodialysis
#3
REVIEW
Mitsushige Sugimoto, Hideo Yasuda, Akira Andoh
Chronic kidney disease (CKD) patients receiving hemodialysis (HD) often develop gastrointestinal abnormalities over their long treatment period. In general, prognosis in such patients is poor due to the development of protein-energy wasting (PEW). Therefore, it is important to clarify the etiology of PEW and to establish better strategies to deal with this condition. Chronic Helicobacter pylori ( H. pylori ) infection in the gastric mucosa has a close association with not only the development of peptic ulcer disease and gastric cancer, but is also associated with abnormal plasma and gastric mucosal ghrelin levels that are seen in malnutrition...
April 21, 2018: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/29684970/-the-effect-of-helicobacter-pylori-infection-on-recurrence-of-gastric-hyperplastic-polyp-after-endoscopic-removal
#4
Kyu Ho Kang, Su Hyun Hwang, Dongwoo Kim, Dae Ha Kim, Seung Young Kim, Jong Jin Hyun, Sung Woo Jung, Ja Seol Koo, Young Kul Jung, Hyung Joon Yim, Sang Woo Lee
Background/Aims: Several previous studies suggest that eradication of Helicobacter pylori ( H. pylori ) leads to the disappearance of gastric hyperplastic polyps. However, little is known about the effect of H. pylori status and eradication on the recurrence of gastric polyps after endoscopic removal. Here, we investigated the recurrence of gastric polyps according to the final H. pylori status in patients who underwent endoscopic removal of gastric hyperplastic polyps. Methods: Between January 2011 and December 2016, patients who underwent endoscopic removal of gastric hyperplastic polyps and were followed-up for more than two months were enrolled...
April 25, 2018: Korean Journal of Gastroenterology, Taehan Sohwagi Hakhoe Chi
https://www.readbyqxmd.com/read/29684969/-the-efficacy-of-rebamipide-or-ecabet-sodium-supplementation-for-helicobacter-pylori-eradication-therapy-compared-with-quadruple-concomitant-regimen
#5
Joonhwan Kim, Kyungwon Kim, Jun Soo Lee, Su Young Kim, Kyung Oh Kim, Yoon Jae Kim, Kwang An Kwon, Dong Kyun Park, Jun Won Chung
Background/Aims: Although some previous studies reported that a treatment combined with mucoprotective agent could improve the eradication rate in dual or triple therapy, there are other reports that question the efficacy of combining these drugs in concomitant therapy (CoCTx). The aim of this study was to investigate the effects of rebamipide or ecabet on the Helicobacter pylori ( H. pylori ) eradication combined with CoCTx. Methods: We retrospectively reviewed the medical records of 277 patients with proven H...
April 25, 2018: Korean Journal of Gastroenterology, Taehan Sohwagi Hakhoe Chi
https://www.readbyqxmd.com/read/29684968/-the-efficacy-of-bismuth-containing-quadruple-therapy-after-moxifloxacin-based-sequential-therapy-failure-in-helicobacter-pylori-eradication
#6
Soohoon Kwon, Dong Ho Lee, Jae Bin Kang, Nayoung Kim, Young Soo Park, Cheol Min Shin, Hyuk Yoon, Yoon Jin Choi
Background/Aims: Moxifloxacin-based sequential therapy showed an excellent eradication rate as the first line treatment of Helicobacter pylori ( H. pylori ) infection. However, to the best of our knowledge, there were only a few studies on the treatment of those with failed moxifloxacin-based sequential therapy. Hence, this study was to investigate the efficacy of bismuth-containing quadruple therapy in those with failed moxifloxacin-based sequential or reverse sequential therapy for H...
April 25, 2018: Korean Journal of Gastroenterology, Taehan Sohwagi Hakhoe Chi
https://www.readbyqxmd.com/read/29682242/eradication-of-helicobacter-pylori-in-iran-a-review
#7
REVIEW
Hafez Fakheri, Mehdi Saberi Firoozi, Zohreh Bari
Helicobacter pylori (H. pylori) infection is one of the most common bacterial infections, affecting almost half of the world's population. It is associated with peptic ulcer disease, gastric adenocarcinoma, and lymphoma. In Iran, the prevalence of H. pylori infection has been reported to be between 36% and 90% in different geographic regions. Several studies have assessed the efficacy of different therapeutic options for firstline and second-line H. pylori eradication in Iran; however, the results are conflicting...
January 2018: Middle East Journal of Digestive Diseases
https://www.readbyqxmd.com/read/29676395/comment-on-first-line-helicobacter-pylori-eradication-with-vonoprazan-clarithromycin-and-metronidazole-in-patients-allergic-to-penicillin
#8
COMMENT
Negin Kashani, Amin Talebi Bezmin Abadi
No abstract text is available yet for this article.
2018: Gastroenterology Research and Practice
https://www.readbyqxmd.com/read/29672300/clinical-significance-of-reddish-depressed-lesions-observed-in-the-gastric-mucosa-after-helicobacter-pylori-eradication
#9
Takahiro Kotachi, Masanori Ito, Tomoyuki Boda, Mariko Kiso, Kazuhiko Masuda, Kosaku Hata, Toru Kawamura, Yoji Sanomura, Masaharu Yoshihara, Shinji Tanaka, Kazuaki Chayama
BACKGROUND AND AIM: Reddish depressed lesions (RDLs) frequently observed in patients following Helicobacter pylori eradication are indistinguishable from gastric cancer. We examined the clinical and histological feature of RDLs and its relevant endoscopic diagnosis including magnifying narrow-band imaging (M-NBI). METHODS: We enrolled 301 consecutive patients with H. pylori eradication who underwent endoscopy using white light imaging (WLI). We examined the prevalence and host factors contributing to the presence of RDLs...
April 19, 2018: Digestion
https://www.readbyqxmd.com/read/29671784/epidemiology-of-helicobacter-pylori-and-caga-positive-infections-and-global-variations-in-gastric-cancer
#10
REVIEW
Jin Young Park, David Forman, Langgeng Agung Waskito, Yoshio Yamaoka, Jean E Crabtree
Gastric cancer is a major health burden and is the fifth most common malignancy and the third most common cause of death from cancer worldwide. Development of gastric cancer involves several aspects, including host genetics, environmental factors, and Helicobacter pylori infection. There is increasing evidence from epidemiological studies of the association of H. pylori infection and specific virulence factors with gastric cancer. Studies in animal models indicate H. pylori is a primary factor in the development of gastric cancer...
April 19, 2018: Toxins
https://www.readbyqxmd.com/read/29671413/non-variceal-upper-gastrointestinal-bleeding
#11
REVIEW
Angel Lanas, Jean-Marc Dumonceau, Richard H Hunt, Mitsuhiro Fujishiro, James M Scheiman, Ian M Gralnek, Helen E Campbell, Alaa Rostom, Càndid Villanueva, Joseph J Y Sung
Non-variceal upper gastrointestinal bleeding (NVUGIB) is bleeding that develops in the oesophagus, stomach or proximal duodenum. Peptic ulcers, caused by Helicobacter pylori infection or use of NSAIDs and low-dose aspirin (LDA), are the most common cause. Although the incidence and mortality associated with NVUGIB have been decreasing owing to considerable advances in the prevention and management of NVUGIB over the past 20 years, it remains a common clinical problem with an annual incidence of ∼67 per 100,000 individuals in the United States in 2012...
April 19, 2018: Nature Reviews. Disease Primers
https://www.readbyqxmd.com/read/29670656/the-antibacterial-activity-of-mass-galla-chinesis-et-camelliae-fermentata-on-helicobacter-pylori-infection
#12
Jing Yu, Hui Ye, Jiang Li, Ning Li, Zong-Ming Shi, Xue-Zhi Zhang
Mass Galla chinesis et camelliae Fermentata ( Chinese gall leaven , CGL) was investigated for activities against Helicobacter pylori (H. pylori) both in vitro and in vivo . The agar dilution method and time-kill curves, as in vitro assays and an in vivo study using a Kunming mice model, were performed. CGL demonstrated a strong anti- Helicobacter pylori activity in vitro with the minimal inhibitory concentrations (MICs) against multiple H. pylori strains of 0.5~8 mg/ml and the decreasing trend time-kill curves when increasing CGL concentrations...
2018: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/29669681/the-diagnosis-and-treatment-of-functional-dyspepsia
#13
Ahmed Madisch
BACKGROUND: Functional dyspepsia (FD) is one of the more common functional disorders, with a prevalence of 10-20%. It affectsthe gastrointestinal tract. METHODS: This article is based on publications retrieved by a selective search of PubMed, with special attention to controlled trials, guidelines, and reviews. RESULTS: Typical dyspeptic symptoms in functional dyspepsia include epigastric pain, sensations of pressure and fullness, nausea, and early subjective satiety...
March 30, 2018: Deutsches Ärzteblatt International
https://www.readbyqxmd.com/read/29669354/effectiveness-and-safety-of-pylera%C3%A2-in-patients-infected-by-helicobacter-pylori-a-multicenter-retrospective-real-life-study
#14
Antonio Tursi, Marilisa Franceschi, Leonardo Allegretta, Edoardo Savarino, Rudi De Bastiani, Walter Elisei, Gianluca Baldassarre, Antonio Ferronato, Serena Scida, Chiara Miraglia, Antonio Penna, Claudio Licci, Giovanni Luca Rizzo, Giuseppe Pranzo, Claudio Cassieri, Giovanni Brandimarte, Marcello Picchio, Francesco Di Mario
BACKGROUND: Our aims were to assess the real life effectiveness and safety of the new bismuth-containing quadruple therapy in a large population of patients infected by Helicobacter pylori. METHODS: Consecutive dyspeptic H. pylori-positive patients were enrolled, both naïve for treatment and already unsuccessfully treated. Patients were treated with Pylera® 3 capsules 4 times/daily plus omeprazole 20 mg or esomeprazole 40 mg 2 times/daily for 10 days. Eradication was confirmed using a urea-breath test (at least 30 days after the end of the treatment)...
April 17, 2018: Digestive Diseases
https://www.readbyqxmd.com/read/29666720/gastric-malt-lymphoma-with-increased-plasma-cell-differentiation-showing-unique-endoscopic-features
#15
Masaya Iwamuro, Takehiro Tanaka, Kenji Nishida, Seiji Kawano, Yoshiro Kawahara, Shogen Ohya, Tadashi Yoshino, Hiroyuki Okada
A 62-year-old woman was diagnosed with extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma) with increased plasma cell differentiation of the stomach. Esophagogastroduodenoscopy showed slightly elevated, whitish lesions in the gastric body. Magnifying endoscopic observation revealed that the gastric surface epithelium was swollen, but the structure was not destroyed or diminished. Elongated, tortuous vasculature was observed on the surface of the whitish lesions. The patient underwent eradication treatment for Helicobacter pylori , which resulted in complete remission...
2018: Case Reports in Gastrointestinal Medicine
https://www.readbyqxmd.com/read/29666614/-helicobacter-pylori-the-latent-human-pathogen-or-an-ancestral-commensal-organism
#16
REVIEW
Jackie Li, Guillermo I Perez-Perez
We dedicated this review to discuss Helicobacter pylori as one of the latest identified bacterial pathogens in humans and whether its role is mainly as a pathogen or a commensal. Diseases associated with this bacterium were highly prevalent during the 19th century and gradually have declined. Most diseases associated with H. pylori occurred in individuals older than 40 years of age. However, acquisition of H. pylori occurs mainly in young children inside the family setting. Prevalence and incidence of H. pylori has had a dramatic change in the last part of the 20th century and beginning of the 21th century...
2018: Frontiers in Microbiology
https://www.readbyqxmd.com/read/29663251/histopathological-findings-in-morbid-obese-patients-undergoing-laparoscopic-sleeve-gastrectomy-does-h-pylori-infection-effective-on-pathological-changes
#17
Ramazan İlyas Öner, Sabri Özdaş
AıM: To determine the prevalence of histopathological findings requiring clinical follow-up in morbidly obese patients undergoing laparoscopic sleeve gastrectomy (LSG) and evaluate the relationship between these findings and Helicobacter pylori as well as to add more data to the published literature in this regard. MATERıAL AND METHODS: Overall, 161 morbidly obese patients with body mass index (BMI) > 40 kg/m2 who underwent LSG between May 1, 2014 and May 31, 2017 were retrospectively included in the study...
April 16, 2018: Obesity Surgery
https://www.readbyqxmd.com/read/29662291/punctual-mutations-in-23s-rrna-gene-of-clarithromycin-resistant-helicobacter-pylori-in-colombian-populations
#18
Andrés Jenuer Matta, Diana Carolina Zambrano, Alvaro Jairo Pazos
AIM: To characterize punctual mutations in 23S rRNA gene of clarithromycin-resistant Helicobacter pylori ( H. pylori ) and determine their association with therapeutic failure. METHODS: PCR products of 23S rRNA gene V domain of 74 H. pylori isolates; 34 resistant to clarithromycin (29 from a low-risk gastric cancer (GC) population: Tumaco-Colombia, and 5 from a high-risk population: Tuquerres-Colombia) and 40 from a susceptible population (28 from Tumaco and 12 from Túquerres) were sequenced using capillary electrophoresis...
April 14, 2018: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/29657940/levofloxacin-containing-versus-clarithromycin-containing-therapy-for-helicobacter-pylori-eradication-a-prospective-randomized-controlled-clinical-trial
#19
Vahid Sebghatollahi, Maryam Soheilipour, Mahsa Khodadoostan, Alireza Shavakhi, Ahmad Shavakhi
Background: This study evaluated the clinical efficacy and tolerability of a 14-day course of bismuth-based quadruple therapy including tinidazole and levofloxacin in compare to a 14-day bismuth-based quadruple therapy including clarithromycin as first-line treatment for Helicobacter pylori infection in Iranian adults. Materials and Methods: The study was a prospective, parallel group, randomized controlled, clinical trial that conducted on 150 patients with H. pylori infection...
2018: Advanced Biomedical Research
https://www.readbyqxmd.com/read/29657020/helicobacter-pylori-infection-aggravates-diet-induced-nonalcoholic-fatty-liver-in-mice
#20
Cong He, Dandan Cheng, Huan Wang, Ketao Wu, Yin Zhu, Nonghua Lu
BACKGROUND: Previous epidemiological studies have suggested a link between Helicobacter pylori (H. pylori) infection and nonalcoholic fatty liver disease (NAFLD), yet animal studies are lacking to elucidate this association. In this study, we evaluated the potential effects of H. pylori infection on NAFLD in mice. METHODS: We first established two strains of H. pylori infected mice model with either chow diet or high fat diet (HFD). The body and liver weight, blood glucose, serum transaminases and lipid levels and markers of hepatic inflammation were measured...
April 12, 2018: Clinics and Research in Hepatology and Gastroenterology
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