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https://www.readbyqxmd.com/read/28097729/the-role-of-orexin-signaling-in-the-ventral-tegmental-area-and-central-amygdala-in-modulating-binge-like-ethanol-drinking-behavior
#1
Jeffrey J Olney, Montserrat Navarro, Todd E Thiele
BACKGROUND: Recent reports have demonstrated that binge-like ethanol drinking leads to an increase in hypothalamic orexin (OX) signaling and that suppressing this signaling via systemic administration of an orexin receptor (OXR) antagonist blocks this behavior; however, the specific OX pathways that modulate this behavior remain unknown. The goal of the present study was to further elucidate the role of the OX system in binge-like ethanol drinking using behavioral, molecular, and pharmacological techniques...
January 17, 2017: Alcoholism, Clinical and Experimental Research
https://www.readbyqxmd.com/read/28097614/comprehensive-and-medically-appropriate-food-support-is-associated-with-improved-hiv-and-diabetes-health
#2
Kartika Palar, Tessa Napoles, Lee L Hufstedler, Hilary Seligman, Fredrick M Hecht, Kimberly Madsen, Mark Ryle, Simon Pitchford, Edward A Frongillo, Sheri D Weiser
Food insecurity is associated with negative chronic health outcomes, yet few studies have examined how providing medically appropriate food assistance to food-insecure individuals may improve health outcomes in resource-rich settings. We evaluated a community-based food support intervention in the San Francisco Bay Area for people living with HIV and/or type 2 diabetes mellitus (T2DM) to determine the feasibility, acceptability, and potential impact of the intervention on nutritional, mental health, disease management, healthcare utilization, and physical health outcomes...
January 17, 2017: Journal of Urban Health: Bulletin of the New York Academy of Medicine
https://www.readbyqxmd.com/read/28088538/perceived-parental-alcohol-problems-and-drinking-patterns-in-youth-a-cross-sectional-study-of-69-030-secondary-education-students-in-denmark
#3
Veronica S C Pisinger, Charlotte A Holst, Pernille Bendtsen, Ulrik Becker, Janne S Tolstrup
The aim of the study was to examine whether young people with parental alcohol problems have different drinking patterns than those without parental alcohol problems. Further, we examined whether the association between parental alcohol problems and young people's drinking patterns differed depending on the gender of the child and the parent, and whether more severe parental alcohol problems and cohabitation with the parent with alcohol problems was associated with earlier and heavier drinking patterns. Data came from the Danish National Youth Study 2014, a web-based national survey...
January 11, 2017: Preventive Medicine
https://www.readbyqxmd.com/read/28076925/the-association-between-electronic-bullying-and-school-absenteeism-among-high-school-students-in-the-united-states
#4
Erin Grinshteyn, Y T Yang
BACKGROUND: We examined the relationship between exposure to electronic bullying and absenteeism as a result of being afraid. METHODS: This multivariate, multinomial regression analysis of the 2013 Youth Risk Behavior Survey data assessed the association between experiencing electronic bullying in the past year and how often students were absent in the last month due to feeling unsafe at/in transit to school. The model controlled for other predictors of school absence including demographics, physical/behavioral health, and risk factors...
February 2017: Journal of School Health
https://www.readbyqxmd.com/read/28072409/alcohol-dose-dependent-dna-methylation-and-expression-in-the-nucleus-accumbens-identifies-coordinated-regulation-of-synaptic-genes
#5
R Cervera-Juanes, L J Wilhelm, B Park, K A Grant, B Ferguson
Alterations in DNA methylation have been associated with alcohol exposure and proposed to contribute to continued alcohol use; however, the molecular mechanisms involved remain obscure. We investigated the escalating effects of alcohol use on DNA methylation, gene expression and predicted neural effects in the nucleus accumbens of rhesus macaques that self-administered 4% alcohol for over 12 months. Using an exploratory approach to identify CpG-rich regions, followed by bisulfite sequencing, the methylation levels of 2...
January 10, 2017: Translational Psychiatry
https://www.readbyqxmd.com/read/28068977/alcohol-management-plans-in-aboriginal-and-torres-strait-islander-indigenous-australian-communities-in-queensland-community-residents-have-experienced-favourable-impacts-but-also-suffered-unfavourable-ones
#6
Alan R Clough, Stephen A Margolis, Adrian Miller, Anthony Shakeshaft, Christopher M Doran, Robyn McDermott, Robert Sanson-Fisher, Valmae Ypinazar, David Martin, Jan A Robertson, Michelle S Fitts, Katrina Bird, Bronwyn Honorato, Simon Towle, Caryn West
BACKGROUND: In Australia, 'Alcohol Management Plans' (AMPs) provide the policy infrastructure for State and Commonwealth Governments to address problematic alcohol use among Aboriginal and Torres Strait Islanders. We report community residents' experiences of AMPs in 10 of Queensland's 15 remote Indigenous communities. METHODS: This cross-sectional study used a two-stage sampling strategy: N = 1211; 588 (48%) males, 623 (52%) females aged ≥18 years in 10 communities...
January 10, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28067964/cardiovascular-consequences-of-binge-drinking-an-integrative-review-with-implications-for-advocacy-policy-and-research
#7
Mariann R Piano, Adriana Mazzuco, Minkyung Kang, Shane A Phillips
Worldwide, binge drinking is a major public health problem. The popularized health risks associated with binge drinking include physical injury and motor vehicle crashes; less attention has been given to the negative effects on the cardiovascular (CV) system. The primary aims of this review were to provide a summary of the adverse effects of binge drinking on the risk and development of CV disease and to review potential pathophysiologic mechanisms. Using specific inclusion criteria, an integrative review was conducted that included data from human experimental, prospective cross-sectional, and cohort epidemiological studies that examined the association between binge drinking and CV conditions such as hypertension, myocardial infarction, stroke, and arrhythmias...
January 9, 2017: Alcoholism, Clinical and Experimental Research
https://www.readbyqxmd.com/read/28063599/-risk-factors-and-psychological-vulnerabilities-to-binge-drinking-in-youth
#8
E De Wever, V Quaglino
For years, a large number of studies have demonstrated the harmful effects of alcohol consumption on the brain and therefore on behavior and cognition. These studies first aimed at identifying the consequences of alcohol abuse consumption, more specifically in pathologies such as alcohol-dependence or Korsakoff syndrome. Researchers then also started to focus on vulnerabilities to alcohol consumption, especially in hyper fast alcohol consumption called binge-drinking (BD). Indeed BD, which is a particularly dangerous form of alcohol consumption, is usually observed in adolescents and young adults...
January 4, 2017: L'Encéphale
https://www.readbyqxmd.com/read/28063279/unintended-impacts-of-alcohol-restrictions-on-alcohol-and-other-drug-use-in-indigenous-communities-in-queensland-australia
#9
Jan A Robertson, Michelle S Fitts, Alan R Clough
BACKGROUND: 'Alcohol Management Plans' (AMPs) with a focus on alcohol restrictions were implemented in 19 discrete Indigenous communities, in 15 Local Government Areas, by the Queensland Government from 2002. Community residents' perceptions and experiences of the impacts of AMPs on local alcohol and drug use are documented. METHODS: A cross-sectional study used quantitative and qualitative survey data collected during 2014-2015 in 10 affected communities. Five had some alcohol available...
January 4, 2017: International Journal on Drug Policy
https://www.readbyqxmd.com/read/28055132/identifying-future-drinkers-behavioral-analysis-of-monkeys-initiating-drinking-to-intoxication-is-predictive-of-future-drinking-classification
#10
Erich J Baker, Nicole A R Walter, Alex Salo, Pablo Rivas, Sharon Moore, Steven Gonzales, Kathleen A Grant
BACKGROUND: The Monkey Alcohol and Tissue Research Resource (MATRR) is a repository and analytics platform for detailed data derived from well-documented Non-Human Primate (NHP) alcohol self-administration studies. This macaque model has demonstrated categorical drinking norms reflective of human drinking populations, resulting in consumption pattern classifications of Very Heavy Drinking (VHD), Heavy Drinking (HD), Binge Drinking (BD), and Low Drinking (LD) individuals. Here we expand on previous findings that suggest ethanol drinking patterns during initial drinking to intoxication can reliably predict future drinking category assignment...
January 5, 2017: Alcoholism, Clinical and Experimental Research
https://www.readbyqxmd.com/read/28052932/lay-understanding-of-the-causes-of-binge-drinking-in-the-united-kingdom-and-australia-a-network-diagram-approach
#11
David A Keatley, Eamonn Ferguson, Adam Lonsdale, Martin S Hagger
Binge drinking is associated with deleterious health, social and economic outcomes. This study explored the lay understanding of the causes of binge drinking in members of the general public in the United Kingdom and Australia. Participants in the United Kingdom (N = 133) and Australia (N = 102) completed a network diagram exercise requiring them to draw causal paths and provide path strength ratings between 12 candidate factors (24-h opening, age, alcohol advertizing, alcohol availability, boredom, drinking culture, income, low cost, parental influence, peer pressure, stress and supermarket discounts) and binge drinking...
January 3, 2017: Health Education Research
https://www.readbyqxmd.com/read/28052857/more-drinking-more-problems-stable-association-between-alcohol-consumption-and-harm-among-swedish-youth-1995-2012
#12
Siri Thor, Jonas Raninen, Jonas Landberg
AIMS: Alcohol consumption among Swedish youth increased during the 1990s. In the following decade, levels declined coinciding with a reduction in the prevalence of self-reported alcohol-related harm. We examine how the trend in self-reported alcohol-related problems among young Swedish alcohol consumers has followed the trend in alcohol consumption during 1995-2012, and test whether the strength of the association between self-reported alcohol consumption and alcohol-related problems within individuals is inversely proportional to the overall level of consumption among youth...
January 4, 2017: Alcohol and Alcoholism: International Journal of the Medical Council on Alcoholism
https://www.readbyqxmd.com/read/28049459/can-psychosocial-and-socio-demographic-questions-help-identify-sexual-risk-among-heterosexually-active-women-of-reproductive-age-evidence-from-britain-s-third-national-survey-of-sexual-attitudes-and-lifestyles-natsal-3
#13
Natalie Edelman, Jackie A Cassell, Richard de Visser, Philip Prah, Catherine H Mercer
BACKGROUND: Contraceptive advice and supply (CAS) and sexually transmitted infection (STI) testing are increasingly provided in primary care. Most risk assessment tools are based on sexual risk behaviours and socio-demographics, for use online or in specialist services. Combining socio-demographic and psychosocial questions (e.g. religious belief and formative experience) may generate an acceptable tool for targeting women in primary care who would benefit from intervention. We aimed to identify psychosocial and socio-demographic factors associated with reporting key sexual risk behaviours among women in the British general population...
January 4, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28032119/increased-synaptic-excitation-and-abnormal-dendritic-structure-of-prefrontal-cortex-layer-v-pyramidal-neurons-following-prolonged-binge-like-consumption-of-ethanol
#14
Paul M Klenowski, Matthew J Fogarty, Masroor Shariff, Arnauld Belmer, Mark C Bellingham, Selena E Bartlett
Long-term alcohol use causes a multitude of neurochemical changes in cortical regions that facilitate the transition to dependence. Therefore, we used a model of long-term, binge-like ethanol consumption in rats to determine the effects on morphology and synaptic physiology of medial prefrontal cortex (mPFC) layer V pyramidal neurons. Following 10 weeks of ethanol consumption, we recorded synaptic currents from mPFC neurons and used neurobiotin filling to analyze their morphology. We then compared these data to measurements obtained from age-matched, water-drinking control rats...
November 2016: ENeuro
https://www.readbyqxmd.com/read/28028047/content-analysis-of-uk-newspaper-and-online-news-representations-of-women-s-and-men-s-binge-drinking-a-challenge-for-communicating-evidence-based-messages-about-single-episodic-drinking
#15
C Patterson, C Emslie, O Mason, G Fergie, S Hilton
OBJECTIVES: In the UK, men's alcohol-related morbidity and mortality still greatly exceeds women's, despite an increase in women's alcohol consumption in recent decades. New UK alcohol guidelines introduce gender-neutral low-risk alcohol consumption guidance. This study explores how UK newspaper and online news represent women's and men's 'binge' drinking to identify opportunities to better align reporting of harmful drinking with evidence. DESIGN: Quantitative and qualitative content analysis of 308 articles published in 7 UK national newspapers and the BBC News website between 1 January 2012 and 31 December 2013...
December 27, 2016: BMJ Open
https://www.readbyqxmd.com/read/28027881/perceived-control-moderates-the-relationship-between-social-capital-and-binge-drinking-longitudinal-findings-from-the-montreal-neighborhood-networks-and-health-aging-monnet-ha-panel
#16
Stephanie Child, Steven Stewart, Spencer Moore
BACKGROUND: Cross-sectional research suggests social capital has negative consequences for problem drinking behaviors. Previous studies have suggested psychosocial resources, including perceived control, may buffer this association. Little research has examined whether such relationships persist longitudinally. METHODS: Random effects models examined between-person relationships among problem drinking, social capital, and perceived control, and whether perceived control moderated the relationship between social capital and drinking...
December 9, 2016: Annals of Epidemiology
https://www.readbyqxmd.com/read/28027422/care-related-predictors-for-negative-intrusive-thoughts-after-prostate-cancer-diagnosis-data-from-the-prospective-lappro-trial
#17
Thordis Thorsteinsdottir, Heiddis Valdimarsdottir, Arna Hauksdottir, Johan Stranne, Ulrica Wilderäng, Eva Haglind, Gunnar Steineck
OBJECTIVE: Negative intrusive thoughts about one's prostate cancer have been associated with depressive mood and impaired quality of life among prostate cancer patients. However, little is known about possible predictors for negative intrusive thoughts among this group. We aimed to identify health- and care-related predictors for such thoughts among a population of men newly diagnosed with prostate cancer and undergoing radical prostatectomy. METHODS: In the LAPPRO-trial, 3154 men (80%) answered study-specific questionnaires at admission and three months after surgery...
December 27, 2016: Psycho-oncology
https://www.readbyqxmd.com/read/28018872/trends-in-binge-drinking-in-canada-from-1996-to-2013-a-repeated-cross-sectional-analysis
#18
Andrew G M Bulloch, Jeanne V A Williams, Dina H Lavorato, Scott B Patten
BACKGROUND: Heavy drinking is a major factor in morbidity and mortality worldwide. Little information is available on trends in Canada regarding alcohol abuse. We sought to estimate abstinence, binge drinking and alcohol intake exceeding low-risk drinking guidelines in the Canadian population from 1996 to 2013. METHODS: The data sources for this analysis were a series of cross-sectional national health surveys of the Canadian population carried out by Statistics Canada between 1996 and 2013...
October 2016: CMAJ Open
https://www.readbyqxmd.com/read/28012834/the-associations-between-e-cigarettes-and-binge-drinking-marijuana-use-and-energy-drinks-mixed-with-alcohol
#19
Sandra Milicic, Scott T Leatherdale
PURPOSE: Use of e-cigarettes by youth is proliferating worldwide, but little is known about the behavioral profile of youth e-cigarette users and the association of e-cigarette use with other health-risky behaviors. This study examines the associations between e-cigarette use and tobacco, marijuana, and alcohol use among a large sample of Canadian youth. METHODS: Using Canadian data from 39,837 grade 9 to 12 students who participated in year 3 (2014-2015) of the COMPASS study, logistic regression models were used to examine how current use of e-cigarettes were associated with tobacco, marijuana, binge drinking, and energy drinks mixed with alcohol...
December 21, 2016: Journal of Adolescent Health: Official Publication of the Society for Adolescent Medicine
https://www.readbyqxmd.com/read/28010167/parental-style-and-its-association-with-substance-use-in-argentinean-youth
#20
Lorena Peña, Elma I Lorenzo-Blanco, Adriana Pérez, Paola Morello, Edna Arillo Santillan, Christy Kollath-Cattano, James F Thrasher, James Sargent, Raúl Mejia
BACKGROUND: In Europe and the United States, family relationships and parenting behavior can influence youth substance use, but less is known about their influence in Latin American countries. OBJECTIVE: To explore whether parenting behavior is associated with substance use among Latin American youth. METHODS: A cross-sectional, school-based survey of middle-school youth (n = 3172) in three Argentinian cities queried tobacco, alcohol, and drug use using items adapted from global youth surveys...
December 23, 2016: Substance Use & Misuse
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