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Binge Drinking

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https://www.readbyqxmd.com/read/29778070/high-intensity-binge-drinking-is-associated-with-alterations-in-spontaneous-neural-oscillations-in-young-adults
#1
Rifqi O Affan, Siyuan Huang, Stephen M Cruz, Lee A Holcomb, Edward Nguyen, Ksenija Marinkovic
Heavy episodic alcohol consumption (also termed binge drinking) contributes to a wide range of health and cognitive deficits, but the associated brain-based indices are poorly understood. The current study used electroencephalography (EEG) to examine spontaneous neural oscillations in young adults as a function of quantity, frequency, and the pattern of their alcohol consumption. Sixty-one young adults (23.4 ± 3.4 years of age) were assigned to binge drinking (BD) and light drinking (LD) groups that were equated on gender, race/ethnic identity, age, educational background, and family history of alcoholism...
January 8, 2018: Alcohol
https://www.readbyqxmd.com/read/29775887/gender-and-age-varying-associations-of-sensation-seeking-and-substance-use-across-young-adulthood
#2
Rebecca J Evans-Polce, Megan S Schuler, John E Schulenberg, Megan E Patrick
INTRODUCTION: Sensation seeking is associated with elevated risk for substance use among adolescents and young adults. However, whether these associations vary across age for young men and women is not well characterized. METHODS: Using data from the Monitoring the Future (MTF) panel study, we examine the age-varying associations of sensation seeking and three types of substance use behavior (binge drinking, cigarette use, and marijuana use) across ages 18 to 30 using time-varying effect modeling...
May 4, 2018: Addictive Behaviors
https://www.readbyqxmd.com/read/29775230/alcohol-enhances-symptoms-and-propensity-for-infection-in-inflammatory-bowel-disease-patients-and-a-murine-model-of-dss-induced-colitis
#3
Abigail R Cannon, Paulius V Kuprys, Adrienne N Cobb, Xianzhong Ding, Anai N Kothari, Paul C Kuo, Joshua M Eberhardt, Adam M Hammer, Niya L Morris, Xiaoling Li, Mashkoor A Choudhry
Over 1.4 million Americans have been diagnosed with inflammatory bowel disease (IBD), and ulcerative colitis (UC) makes up approximately half of those diagnoses. As a disease, UC cycles between periods of remission and flare, which is characterized by intense abdominal pain, increased weight loss, intestinal inflammation, rectal bleeding, and dehydration. Interestingly, a widespread recommendation to IBD patients for avoidance of a flare period is "Don't Drink Alcohol" as recent work correlated alcohol consumption with increased GI symptoms in patients with IBD...
May 18, 2018: Journal of Leukocyte Biology
https://www.readbyqxmd.com/read/29753887/peri-adolescent-drinking-of-ethanol-and-or-nicotine-modulates-astroglial-glutamate-transporters-and-metabotropic-glutamate-receptor-1-in-female-alcohol-preferring-rats
#4
Fawaz Alasmari, Richard L Bell, P S S Rao, Alaa M Hammad, Youssef Sari
Impairment in glutamate neurotransmission mediates the development of dependence upon nicotine (NIC) and ethanol (EtOH). Previous work indicated that continuous access to EtOH or phasic exposure to NIC reduces expression of the glutamate transporter-1 (GLT-1) and cystine/glutamate antiporter (xCT) but not the glutamate/aspartate transporter (GLAST). Additionally, metabotropic glutamate receptors (mGluRs) expression was affected following exposure to EtOH or NIC. However, little is known about the effects of EtOH and NIC co-consumption on GLT-1, xCT, GLAST, and mGluR1 expression...
May 10, 2018: Pharmacology, Biochemistry, and Behavior
https://www.readbyqxmd.com/read/29753371/cardiovascular-events-in-alcoholic-syndrome-with-alcohol-withdrawal-history-results-from-the-national-inpatient-sample
#5
Parasuram Krishnamoorthy, Aditi Kalla, Vincent M Figueredo
BACKGROUND: Epidemiologic studies suggest reduced cardiovascular disease (CVD) events with moderate alcohol consumption. However, heavy and binge drinking may be associated with higher CVD risk. Utilizing the Nationwide Inpatient Sample, we studied the association between a troublesome alcohol history (TAH), defined as those with diagnoses of both chronic alcohol syndrome and acute withdrawal history and CVD events. METHODS: Patients >18 years with diagnoses of both chronic alcohol syndrome and acute withdrawal using the International Classification of Diseases-Ninth Edition-Clinical Modification (ICD-9-CM) codes 303...
May 2018: American Journal of the Medical Sciences
https://www.readbyqxmd.com/read/29753117/pharmacological-inhibition-of-receptor-protein-tyrosine-phosphatase-%C3%AE-%C3%AE-ptprz1-modulates-behavioral-responses-to-ethanol
#6
Rosalía Fernández-Calle, Marta Vicente-Rodríguez, Miryam Pastor, Esther Gramage, Bruno Di Geronimo, José María Zapico, Claire Coderch, Carmen Pérez-García, Amy W Lasek, Beatriz de Pascual-Teresa, Ana Ramos, Gonzalo Herradón
Pleiotrophin (PTN) and Midkine (MK) are neurotrophic factors that are upregulated in the prefrontal cortex after alcohol administration and have been shown to reduce ethanol drinking and reward. PTN and MK are the endogenous inhibitors of Receptor Protein Tyrosine Phosphatase (RPTP) β/ζ (a.k.a. PTPRZ1, RPTPβ, PTPζ), suggesting a potential role for this phosphatase in the regulation of alcohol effects. To determine if RPTPβ/ζ regulates ethanol consumption, we treated mice with recently developed small-molecule inhibitors of RPTPβ/ζ (MY10, MY33-3) before testing them for binge-like drinking using the drinking in the dark protocol...
May 9, 2018: Neuropharmacology
https://www.readbyqxmd.com/read/29752804/evaluating-behavioral-health-surveillance-systems
#7
Alejandro Azofeifa, Donna F Stroup, Rob Lyerla, Thomas Largo, Barbara A Gabella, C Kay Smith, Benedict I Truman, Robert D Brewer, Nancy D Brener
In 2015, more than 27 million people in the United States reported that they currently used illicit drugs or misused prescription drugs, and more than 66 million reported binge drinking during the previous month. Data from public health surveillance systems on drug and alcohol abuse are crucial for developing and evaluating interventions to prevent and control such behavior. However, public health surveillance for behavioral health in the United States has been hindered by organizational issues and other factors...
May 10, 2018: Preventing Chronic Disease
https://www.readbyqxmd.com/read/29749666/adverse-adult-consequences-of-different-alcohol-use-patterns-in-adolescence-an-integrative-analysis-of-data-to-age-30-years-from-four-australasian-cohorts
#8
Edmund Silins, L John Horwood, Jake M Najman, George C Patton, John W Toumbourou, Craig A Olsson, Delyse M Hutchinson, Louisa Degenhardt, David Fergusson, Denise Becker, Joseph M Boden, Rohan Borschmann, Maria Plotnikova, George J Youssef, Robert J Tait, Philip Clare, Wayne D Hall, Richard P Mattick
BACKGROUND AND AIMS: Studies have linked adolescent alcohol use with adverse consequences in adulthood; yet it is unclear how strong the associations are and to what extent they may be due to confounding. Our aim was to estimate the strength of association between different patterns of adolescent drinking and longer-term psychosocial harms taking into account individual, family, and peer factors. DESIGN: Participant-level data were integrated from four long running longitudinal studies: Australian Temperament Project; Christchurch Health and Development Study; Mater Hospital and University of Queensland Study of Pregnancy; Victorian Adolescent Health Cohort Study...
May 10, 2018: Addiction
https://www.readbyqxmd.com/read/29749264/religiosity-crime-and-drug-use-among-juvenile-offenders-a-test-of-reciprocal-relationships-over-time
#9
Sung Joon Jang
This article examines whether an individual's religiosity has reciprocal relationships with crime and drug use among juvenile offenders. Structural equation modeling is applied to analyze 11-wave panel data from a study of juveniles adjudicated or found guilty of a serious offense in two states. Offenders' religiosity is measured both objectively (participation in religious activities) and subjectively (religious salience, experiences, and efficacy). While holding constant an offender's exposure time (the proportion of time on the street), previous levels of crime and drug use, and sociodemographic controls, this study found the relationship between religiosity and crime (i...
May 1, 2018: International Journal of Offender Therapy and Comparative Criminology
https://www.readbyqxmd.com/read/29745689/shame-predicts-revictimization-in-victims-of-childhood-violence-a-prospective-study-of-a-general-norwegian-population-sample
#10
Helene Flood Aakvaag, Siri Thoresen, Ida Frugård Strøm, Mia Myhre, Ole Kristian Hjemdal
OBJECTIVE: Victims of childhood violence often experience new victimization in adult life. However, risk factors for such revictimization are poorly understood. In this longitudinal study, we investigated whether violence-related shame and guilt were associated with revictimization. METHOD: Young adults (age = 17-35) exposed to childhood violence (n = 505) were selected from a (Country) population study of 6,589 persons (Wave 1), and reinterviewed by telephone 12-18 months later (Wave 2)...
May 10, 2018: Psychological Trauma: Theory, Research, Practice and Policy
https://www.readbyqxmd.com/read/29743872/pre-conceptional-and-peri-gestational-maternal-binge-alcohol-drinking-produces-inheritance-of-mood-disturbances-and-alcohol-vulnerability-in-the-adolescent-offspring
#11
Anna Brancato, Valentina Castelli, Angela Cavallaro, Gianluca Lavanco, Fulvio Plescia, Carla Cannizzaro
Although binge drinking is on the rise in women of reproductive age and during pregnancy, the consequences in the offspring, in particular the inheritance of alcohol-related mood disturbances and alcohol abuse vulnerability, are still poorly investigated. In this study, we modeled both Habitual- and Binge Alcohol Drinking (HAD and BAD) in female rats by employing a two-bottle choice paradigm, with 20% alcohol and water. The exposure started 12 weeks before pregnancy and continued during gestation and lactation...
2018: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/29738795/animal-models-of-binge-drinking-current-challenges-to-improve-face-validity
#12
REVIEW
Jérôme Jeanblanc, Benjamin Rolland, Fabien Gierski, Margaret P Martinetti, Mickael Naassila
Binge drinking (BD), i.e., consuming a large amount of alcohol in a short period of time, is an increasing public health issue. Though no clear definition has been adopted worldwide the speed of drinking seems to be a keystone of this behavior. Developing relevant animal models of BD is a priority for gaining a better characterization of the neurobiological and psychobiological mechanisms underlying this dangerous and harmful behavior. Until recently, preclinical research on BD has been conducted mostly using forced administration of alcohol, but more recent studies used scheduled access to alcohol, to model more voluntary excessive intakes, and to achieve signs of intoxications that mimic the human behavior...
May 5, 2018: Neuroscience and Biobehavioral Reviews
https://www.readbyqxmd.com/read/29737073/-determinants-of-drinking-relapse-after-treatments-in-patients-with-alcohol-dependence-in-sichuan-province
#13
Zhe Gao, Zhuo Wang, Bing-Rong Cao, Ying He, Rong-Jing Xu, Jing Li
OBJECTIVE: To identify factors that influent drinking relapse after treatments in patients with alcohol dependence in Sichuan province. METHODS: Data were collected in 10 cities of Sichuan province from September 2014 to June 2015,involving 599 patients who received treatments for alcohol dependence. A questionnaire survey was administered on these patients one year after discharge through face to face interviews,collecting data in relation to their demographic characteristics,drinking over the past year,smoking,mood and level of stress...
March 2018: Sichuan da Xue Xue Bao. Yi Xue Ban, Journal of Sichuan University. Medical Science Edition
https://www.readbyqxmd.com/read/29736338/are-lower-levels-of-physical-activity-and-self-rated-fitness-associated-with-higher-levels-of-psychological-distress-in-croatian-young-adults-a-cross-sectional-study
#14
Lovro Štefan, Goran Sporiš, Tomislav Krističević
Background: Although previous evidence has shown that physical activity and physical fitness lower the level of psychological distress, little is known of simultaneous associations between of physical activity and physical fitness and with psychological distress, especially in young adults. Therefore, the main purpose of the present study was to explore both separate and simultaneous association between physical activity and physical fitness with psychological distress. Methods: Participants in this cross-sectional study were 2,100 university students (1,041 men and 1,059 women) chosen from eight faculties in the city of Zagreb...
2018: PeerJ
https://www.readbyqxmd.com/read/29734829/latent-growth-and-dynamic-structural-equation-models
#15
Kevin J Grimm, Nilam Ram
Latent growth models make up a class of methods to study within-person change-how it progresses, how it differs across individuals, what are its determinants, and what are its consequences. Latent growth methods have been applied in many domains to examine average and differential responses to interventions and treatments. In this review, we introduce the growth modeling approach to studying change by presenting different models of change and interpretations of their model parameters. We then apply these methods to examining sex differences in the development of binge drinking behavior through adolescence and into adulthood...
May 7, 2018: Annual Review of Clinical Psychology
https://www.readbyqxmd.com/read/29734102/low-doses-of-methylmercury-intoxication-solely-or-associated-to-ethanol-binge-drinking-induce-psychiatric-like-disorders-in-adolescent-female-rats
#16
Ivaldo Jesus Almeida Belém-Filho, Paula Cardoso Ribera, Aline Lima Nascimento, Antônio Rafael Quadros Gomes, Rafael Rodrigues Lima, Maria Elena Crespo-Lopez, Marta Chagas Monteiro, Enéas Andrade Fontes-Júnior, Marcelo Oliveira Lima, Cristiane Socorro Ferraz Maia
Methylmercury (MeHg) is an environmental contaminant that provokes damage to developing brain. Simultaneously, the consumption of ethanol among adolescents has increased. Evidence concerning the effects of MeHg low doses per se or associated with ethanol during adolescence are scarce. Thus, we investigate behavioral disorders resulted from exposure to MeHg low doses and co-intoxicated with ethanol in adolescent rats. Wistar rats received chronic exposure to low doses of MeHg (40 μg/kg/day for 5 weeks) and/or ethanol binge drinking (3 g/kg/day at 3 days per week for 5 weeks)...
April 30, 2018: Environmental Toxicology and Pharmacology
https://www.readbyqxmd.com/read/29730159/fxr-deletion-in-hepatocytes-does-not-affect-the-severity-of-alcoholic-liver-disease-in-mice
#17
Min Zhang, Bo Kong, Mingxing Huang, Ruixuan Wan, Laura E Armstrong, Justin D Schumacher, Daniel Rizzolo, Monica D Chow, Yi-Horng Lee, Grace L Guo
Emerging evidence has shown that FXR activation ameliorates the development of alcoholic liver diseases (ALD) while whole-body deficiency of FXR in mice leads to more severe ALD. However, it's unknown whether the enhanced susceptibility to ALD development in FXR-/- mice is due to deficiency of hepatic FXR or increased toxicity secondary to increased bile acid (BA) levels. Hepatocyte-specific FXR knockout mice (FXRhep-/- ) present similar BA levels compared to wild-type mice, and are therefore a useful model to study a direct role of hepatic FXR in ALD development...
April 23, 2018: Digestive and Liver Disease
https://www.readbyqxmd.com/read/29724742/light-moderate-alcohol-consumption-and-left-ventricular-function-among-healthy-middle-aged-adults-the-hunt-study
#18
Katalin Gémes, Imre Janszky, Linn Beate Strand, Krisztina D László, Staffan Ahnve, Lars J Vatten, Håvard Dalen, Kenneth J Mukamal
OBJECTIVES: To investigate the association between alcohol consumption and left ventricular (LV) function in a population with low average alcohol intake. DESIGN, SETTING AND PARTICIPANTS: A total of 1296 healthy participants, free from cardiovascular diseases, were randomly selected from the third wave of the Norwegian HUNT study (2006-2008) and underwent echocardiography. After validation of the inclusion criteria, 30 participants were excluded due to arrhythmias or myocardial or valvular pathology...
May 3, 2018: BMJ Open
https://www.readbyqxmd.com/read/29719219/deriving-a-clinical-prediction-rule-to-target-sexual-healthcare-to-women-attending-british-general-practices
#19
N L Edelman, J A Cassell, C H Mercer, S A Bremner, C I Jones, A Gersten, R O deVisser
Some women attending General Practices (GPs) are at higher risk of unintended pregnancy (RUIP) and sexually transmitted infections (STI) than others. A clinical prediction rule (CPR) may help target resources using psychosocial questions as an acceptable, effective means of assessment. The aim was to derive a CPR that discriminates women who would benefit from sexual health discussion and intervention. Participants were recruited to a cross-sectional survey from six GPs in a city in South-East England in 2016...
April 29, 2018: Preventive Medicine
https://www.readbyqxmd.com/read/29713979/molecular-surveillance-of-vittaforma-like-microsporidia-by-a-small-volume-procedure-in-drinking-water-source-in-taiwan-evidence-for-diverse-and-emergent-pathogens
#20
Jung-Sheng Chen, Bing-Mu Hsu, Hsin-Chi Tsai, Yu-Pin Chen, Tung-Yi Huang, Kuan-Ying Li, Dar-Der Ji, Herng-Sheng Lee
Vittaforma corneae belongs to microsporidia, which include over 1500 species of opportunistic obligate intracellular fungi infecting almost all known animal taxa. Although outbreaks of ocular infections caused by waterborne V. corneae have been reported in recent years, little is known about the occurrence of this pathogen in aquatic environments. In this study, 50 water samples from rivers and reservoirs around Taiwan in two seasons were analyzed to explore the presence of this pathogen in natural aquatic environments...
April 30, 2018: Environmental Science and Pollution Research International
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