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https://www.readbyqxmd.com/read/28329863/understanding-the-mechanisms-of-change-in-a-lifestyle-intervention-for-older-adults
#1
Christine Juang, Bob G Knight, Mike Carlson, Stacey L Schepens Niemiec, Cheryl Vigen, Florence Clark
Purpose of the Study: This study investigated the mechanisms of change underlying an activity-based lifestyle intervention, an occupational therapy program aimed at promoting healthy habits, and routines in older adults. We examined two activity-relevant factors as potential mediators linking the intervention to reduced symptoms of depression: activity frequency and global perceptions of activity significance. Social connections and perceived control were assessed to understand how activity-related factors relate to reduced symptoms of depression...
January 24, 2017: Gerontologist
https://www.readbyqxmd.com/read/28328928/fraudulent-id-using-face-morphs-experiments-on-human-and-automatic-recognition
#2
David J Robertson, Robin S S Kramer, A Mike Burton
Matching unfamiliar faces is known to be difficult, and this can give an opportunity to those engaged in identity fraud. Here we examine a relatively new form of fraud, the use of photo-ID containing a graphical morph between two faces. Such a document may look sufficiently like two people to serve as ID for both. We present two experiments with human viewers, and a third with a smartphone face recognition system. In Experiment 1, viewers were asked to match pairs of faces, without being warned that one of the pair could be a morph...
2017: PloS One
https://www.readbyqxmd.com/read/28328161/synthesis-in-vitro-evaluation-and-68-ga-radiolabeling-of-cdp1-towards-pet-ct-imaging-of-bacterial-infection
#3
Jyotibon Dutta, Sooraj Baijnath, Anou M Somboro, Savania Nagiah, Fernando Albericio, Beatriz G de la Torre, Biljana Marjanovic-Painter, Jan Rijn Zeevaart, Mike Sathekge, Hendrik G Kruger, Anil Chuturgoon, Tricia Naicker, Thomas Ebenhan, Thavendran Govender
Bacterial infections are a major concern in the human health sector due to poor diagnosis and development of multi drug resistant strains. PET/CT provides a means for the noninvasive detection and localization of the infectious foci; however, the radiotracers available are either cumbersome to prepare or their exact contribution towards the imaging is not yet established. Human antimicrobial peptides are of interest for development as PET radiotracers as they are an integral component of the immune system, non-immunogenic towards the recipient and show selectivity towards pathogens such as bacteria...
March 22, 2017: Chemical Biology & Drug Design
https://www.readbyqxmd.com/read/28324871/herd-specific-random-regression-carcass-profiles-for-beef-cattle-after-adjustment-for-animal-genetic-merit
#4
Tanya M Englishby, Kirsty L Moore, Donagh P Berry, Mike P Coffey, Georgios Banos
Abattoir data are an important source of information for the genetic evaluation of carcass traits, but also for on-farm management purposes. The present study aimed to quantify the contribution of herd environment to beef carcass characteristics (weight, conformation score and fat score) with particular emphasis on generating finishing herd-specific profiles for these traits across different ages at slaughter. Abattoir records from 46,115 heifers and 78,790 steers aged between 360 and 900days, and from 22,971 young bulls aged between 360 and 720days, were analysed...
March 7, 2017: Meat Science
https://www.readbyqxmd.com/read/28324622/screening-wild-and-semi-free-ranging-great-apes-for-putative-sexually-transmitted-diseases-evidence-of-trichomonadidae-infections
#5
Julie Rushmore, Andrew B Allison, Erin E Edwards, Ujwal Bagal, Sonia Altizer, Mike R Cranfield, Travis C Glenn, Hsi Liu, Antoine Mudakikwa, Lawrence Mugisha, Martin N Muller, Rebecca M Stumpf, Melissa Emery Thompson, Richard Wrangham, Michael J Yabsley
No abstract text is available yet for this article.
April 2017: American Journal of Primatology
https://www.readbyqxmd.com/read/28324000/trh-action-is-impaired-in-pituitaries-of-male-igsf1-deficient-mice
#6
Marc-Olivier Turgeon, Tanya L Silander, Denica Doycheva, Xiao-Hui Liao, Marc Rigden, Luisina Ongaro, Xiang Zhou, Sjoerd D Joustra, Jan M Wit, Mike G Wade, Heike Heuer, Samuel Refetoff, Daniel J Bernard
Loss-of-function mutations in the X-linked immunoglobulin superfamily, member 1 (IGSF1) gene cause central hypothyroidism. IGSF1 is a transmembrane glycoprotein of unknown function expressed in TSH-producing thyrotrope cells of the anterior pituitary gland. The protein is co-translationally cleaved, with only its C-terminal domain (CTD) being trafficked to the plasma membrane. Most intragenic IGSF1 mutations in humans map to the CTD. Here, we used CRISPR-Cas9 to introduce a loss-of-function mutation into the IGSF1-CTD in mice...
January 13, 2017: Endocrinology
https://www.readbyqxmd.com/read/28321162/mortality-associated-with-gastrointestinal-bleeding-in-children-a-retrospective-cohort-study
#7
Thomas M Attard, Mikaela Miller, Chaitanya Pant, Ashwath Kumar, Mike Thomson
AIM: To determine the clinical characteristics of children with gastrointestinal bleeding (GIB) who died during the course of their admission. METHODS: We interrogated the Pediatric Hospital Information System database, including International Classification of Diseases, Current Procedural Terminology and Clinical Transaction Classification coding from 47 pediatric tertiary centers extracting the population of patients (1-21 years of age) admitted (inpatient or observation) with acute, upper or indeterminate GIB (1/2007-9/2015)...
March 7, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/28320692/longitudinal-changes-in-psychological-states-in-online-health-community-members-understanding-the-long-term-effects-of-participating-in-an-online-depression-community
#8
Albert Park, Mike Conway
BACKGROUND: Major depression is a serious challenge at both the individual and population levels. Although online health communities have shown the potential to reduce the symptoms of depression, emotional contagion theory suggests that negative emotion can spread within a community, and prolonged interactions with other depressed individuals has potential to worsen the symptoms of depression. OBJECTIVE: The goals of our study were to investigate longitudinal changes in psychological states that are manifested through linguistic changes in depression community members who are interacting with other depressed individuals...
March 20, 2017: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/28320355/severe-war-related-trauma-and-personality-pathology-a-case-control-study
#9
Jasna Munjiza, Dolores Britvic, Maja Radman, Mike J Crawford
BACKGROUND: Exposure to war-related trauma has long been recognised to have an adverse effect on mental health. We attempted to investigate whether people who have clinically significant personality-related problems 15 years after a war are more likely to have been exposed to severe war-related trauma than those who do not have significant personality difficulties. METHODS: A case -control study was conducted in southern Croatia, fifteen years after the 1991-1995 war...
March 21, 2017: BMC Psychiatry
https://www.readbyqxmd.com/read/28319601/effectiveness-of-double-balloon-enteroscopy-facilitated-polypectomy-in-paediatric-patients-with-peutz-jeghers-syndrome
#10
Dalia Belsha, Arun Urs, Thomas Attard, Mike Thomson
BACKGROUND: Sizable small-bowel (SB) polyps in Peutz-Jeghers syndrome (PJS) pose a high risk for intussusception, often necessitating laparotomy and intraoperative-enteroscopy (IOE). This series examines the effectiveness of double-balloon enteroscopy (DBE) facilitated polypectomy for pediatric patients with PJS. METHODS: Prospective analysis of collected data (6 years) on all patients with PJS referred for DBE-facilitated SB polypectomy at a pediatric tertiary-referral center...
March 17, 2017: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/28319294/activation-of-sf6-at-platinum-complexes-formation-of-sf3-derivatives-and-their-application-in-deoxyfluorination-reactions
#11
Claudia Berg, Thomas Braun, Mike Ahrens, Philipp Wittwer, Roy Herrmann
The activation of SF6 at [Pt(PR3 )2 ] R=Cy, iPr complexes in the presence of PR3 led selectively and in an unprecedented reaction route to the generation of the SF3 complexes trans-[Pt(F)(SF3 )(PR3 )2 ]. These can also be synthesized from SF4 and the SF2 derivative trans-[Pt(F)(SF2 )(PCy3 )2 ][BF4 ] was characterized by X-ray crystallography. trans-[Pt(F)(SF3 )(PR3 )2 ] complexes are useful tools for deoxyfluorination reactions and novel fluorido complexes bearing a SOF ligand are formed. Based on these studies a process for the deoxyfluorination of ketones was developed with SF6 as fluorinating agent...
March 20, 2017: Angewandte Chemie
https://www.readbyqxmd.com/read/28319273/gastric-microbiota-features-associated-with-cancer-risk-factors-and-clinical-outcomes-a-pilot-study-in-gastric-cardia-cancer-patients-from-shanxi-china
#12
Guoqin Yu, Nan Hu, Lemin Wang, Chaoyu Wang, Xiao-You Han, Mike Humphry, Jacques Ravel, Christian C Abnet, Philip R Taylor, Alisa M Goldstein
Little is known about the link between gastric microbiota and the epidemiology of gastric cancer. In order to determine the epidemiologic and clinical relevance of gastric microbiota, we used 16S ribosomal RNA gene sequencing analysis to characterize the composition and structure of the gastric microbial community of 80 paired samples (non-malignant and matched tumor tissues) from gastric cardia adenocarcinoma (GCA) patients in Shanxi, China. We also used PICRUSt to predict microbial functional profiles. Compared to patients without family history of upper gastrointestinal (UGI) cancer in the non-malignant gastric tissue microbiota, patients with family history of UGI cancer had higher Helicobacter pylori (Hp) relative abundance (median: 0...
March 20, 2017: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/28318825/riparian-erosion-vulnerability-model-based-on-environmental-features
#13
Alejandra Botero-Acosta, Maria L Chu, Jorge A Guzman, Patrick J Starks, Daniel N Moriasi
Riparian erosion is one of the major causes of sediment and contaminant load to streams, degradation of riparian wildlife habitats, and land loss hazards. Land and soil management practices are implemented as conservation and restoration measures to mitigate the environmental problems brought about by riparian erosion. This, however, requires the identification of vulnerable areas to soil erosion. Because of the complex interactions between the different mechanisms that govern soil erosion and the inherent uncertainties involved in quantifying these processes, assessing erosion vulnerability at the watershed scale is challenging...
March 16, 2017: Journal of Environmental Management
https://www.readbyqxmd.com/read/28318512/understanding-children-s-heart-surgery-data-a-cross-disciplinary-approach-to-codevelop-a-website
#14
REVIEW
Christina Pagel, Emily Jesper, Joanne Thomas, Emily Blackshaw, Tim Rakow, Mike Pearson, David Spiegelhalter
Risk-adjusted survival statistics after children's heart surgery are published annually in the United Kingdom. Interpreting these statistics is difficult, and better resources about how to interpret survival data are needed. Here we describe how a multidisciplinary team of mathematicians, psychologists, and a charity worked with parents of heart surgery children and other users to codevelop online resources to present survival outcomes. Early and ongoing involvement of users was crucial and considerably changed the content, scope, and look of the website, and the formal psychology experiments provided deeper insight...
March 15, 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/28318397/baiba-does-not-regulate-ucp-3-expression-in-human-skeletal-muscle-as-a-response-to-aerobic-exercise
#15
Flor E Morales, Jeffrey S Forsse, Thomas L Andre, Sarah K McKinley-Barnard, Paul S Hwang, Ian G Anthony, Grant M Tinsley, Mike Spillane, Peter W Grandjean, Alejandro Ramirez, Darryn S Willoughby
OBJECTIVE: β-Aminoisobutyric acid (BAIBA) has shown to modulate uncoupling protein (UCP)-1 expression, which is mainly expressed in white adipose tissue; however, no studies to date have analyzed its potential effect on the main uncoupling protein of skeletal muscle, UCP-3. The main goal of this study was to assess the potential effect of acute aerobic exercise on serum BAIBA and skeletal muscle UCP-3. The secondary goal was to assess the potential involvement of the transcription factors proliferator-activated receptor gamma coactivator 1-alpha (PGC-1α) and peroxisome proliferator-activated receptor alpha (PPARα), as well as free fatty acids (FFAs) in UCP-3 expression...
March 20, 2017: Journal of the American College of Nutrition
https://www.readbyqxmd.com/read/28317684/comparison-of-the-performance-and-safety-of-2-ophthalmic-viscosurgical-devices-in-cataract-surgery
#16
Gerd U Auffarth, Florian N Auerbach, Tanja Rabsilber, José A Gegúndez, Ricardo Cuiña, Yves Renard, Paolo Vinciguerra, Fabrizio Camesasca, Francoise Van Cauwenberge, Thierry Amzallag, Gysbert Van Setten, Mike P Holzer
PURPOSE: To compare the clinical performance and safety of 2 ophthalmic viscosurgical devices (OVDs)-Twinvisc (OVD 1) and Duovisc (OVD 2)-in cataract surgery. SETTING: European multicenter study. DESIGN: Prospective randomized controlled study. METHODS: Patients with cataract had phacoemulsification and intraocular lens implantation in 1 eye. They were randomly assigned to receive OVD 1 or OVD 2. Preoperative and postoperative examinations over 3 months included mean intraocular pressure (IOP), incidence of IOP peaks (≥30 mm Hg and ≥24 mm Hg), endothelial cell count (ECC), corneal thickness, and intraocular inflammation...
January 2017: Journal of Cataract and Refractive Surgery
https://www.readbyqxmd.com/read/28317470/anthropology-brokerage-and-collaboration-in-the-development-of-a-tongan-public-psychiatry-local-lessons-for-global-mental-health
#17
Mike Poltorak
The Global Mental Health (GMH) movement has raised questions of the translatability of psychiatric concepts and the challenges of community engagement. In Tonga, the local psychiatrist Dr Puloka successfully established a publicly accessible psychiatry that has improved admission rates for serious mental illnesses and addressed some of the stigma attached to diagnosis. On the basis of historical analysis and ethnographic fieldwork with healers, doctors, and patients since 1998, this article offers an ethnographic contextualization of the development and reception of Puloka's three key interventions during the 1990s: (a) collaboration with traditional healers; (b) translation of psychiatric diagnoses into local cultural concepts; and (c) encouraging freedom of movement and legal appeal to involuntary admission...
December 2016: Transcultural Psychiatry
https://www.readbyqxmd.com/read/28316282/motion-compensated-cine-cmr-of-the-fetal-heart-using-radial-undersampling-and-compressed-sensing
#18
Christopher W Roy, Mike Seed, John C Kingdom, Christopher K Macgowan
BACKGROUND: To develop and evaluate a reconstruction framework for high resolution time-resolved CMR of the fetal heart in the presence of motion. METHODS: Data were acquired using a golden angle radial trajectory in seven fetal subjects and reconstructed as real-time images to detect fetal movement. Data acquired during through-plane motion were discarded whereas in-plane motion was corrected. A fetal cardiac gating signal was extracted to sort the corrected data by cardiac phase, allowing reconstruction of cine images...
March 20, 2017: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/28315594/goal-neglect-fluid-intelligence-and-processing-speed-manipulating-instruction-load-and-inter-stimulus-interval
#19
Matthew H Iveson, Sergio Della Sala, Mike Anderson, Sarah E MacPherson
Goal maintenance is the process where task rules and instructions are kept active to exert their control on behavior. When this process fails, an individual may ignore a rule while performing the task, despite being able to describe it after task completion. Previous research has suggested that the goal maintenance system is limited by the number of concurrent rules which can be maintained during a task, and that this limit is dependent on an individual's level of fluid intelligence. However, the speed at which an individual can process information may also limit their ability to use task rules when the task demands them...
March 15, 2017: Acta Psychologica
https://www.readbyqxmd.com/read/28314305/prediction-of-postoperative-risks-in-laparoscopic-partial-nephrectomy-using-renal-mayo-adhesive-probability-and-renal-pelvic-score
#20
Simone Bier, Stefan Aufderklamm, Tilman Todenhöfer, Stephan Kruck, Karoline Schuster, Steffen Rausch, Ahmed Othman, Mike Notohamiprodjo, Konstantin Nikolaou, Christian Schwentner, Arnulf Stenzl, Georg Bier, Jens Bedke
AIM: To evaluate the Mayo Adhesive Probability (MAP) score, renal pelvis score, and RENAL nephrometry score for the prediction of surgical outcome in patients with renal masses undergoing laparoscopic partial nephrectomy at a single center. PATIENTS AND METHODS: A total of 280 patients who underwent laparoscopic partial nephrectomy were identified retrospectively. Thirty-eight patients were excluded because of a lack of preoperative imaging. The outcome measures included surgical technique, patient characteristics, MAP score, renal-pelvis-score, RENAL nephrometry score, and complication rates according to the Clavien-Dindo classification...
March 2017: Anticancer Research
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