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Flax seed oil

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https://www.readbyqxmd.com/read/27909031/a-topical-gel-from-flax-seed-oil-compared-with-hand-splint-in-carpal-tunnel-syndrome-a-randomized-clinical-trial
#1
Mohammad Setayesh, Amir Reza Sadeghifar, Nozar Nakhaee, Mohammad Kamalinejad, Hossein Rezaeizadeh
This study compared the therapeutic effect of flax seed oil topical gel and hand splint in the treatment of carpal tunnel syndrome. This study was a randomized clinical trial. Forty-nine patients, 96 hands, with mild to moderate idiopathic carpal tunnel syndrome were divided into 2 groups randomly. One group was treated by topical gel and the other group by hand splint. Intensity of symptoms and function before and after intervention was measured via Boston Carpal Tunnel Questionnaire. After intervention, the ANCOVA showed a significant difference between the symptom and function scores of the 2 groups...
December 1, 2016: Journal of Evidence-based Complementary & Alternative Medicine
https://www.readbyqxmd.com/read/27894899/dietary-flax-seed-oil-and-or-vitamin-e-improve-sperm-parameters-of-cloned-goats-following-freezing-thawing
#2
Rohollah Kargar, Mohsen Forouzanfar, Gholamreza Ghalamkari, Mohammad Hossein Nasr Esfahani
Semen cryopreservation is affected by individual differences and use of clones animal from the same source is the main tool to eliminate genetic variation. Among many nutrients that are necessary for fertility, essential fatty acids and antioxidants are vital for production of healthy sperm by improving sperm membrane integrity and protecting sperm from oxidative stress. The goal of the current study was to investigate whether a flax seed oil or/and Vitamin E dietary supplementation could improve semen quality of cloned bucks following semen cryopreservation...
November 25, 2016: Cryobiology
https://www.readbyqxmd.com/read/27375853/effect-of-supplementation-of-feed-with-flaxseed-linumusitatisimum-oil-on-libido-and-semen-quality-of-nilli-ravi-buffalo-bulls
#3
Syed Mazhar Hussain Shah, Shujait Ali, Muhammad Zubair, Huma Jamil, Nazir Ahmad
BACKGROUND: The current study was designed to investigate the effect of supplementation of Flaxseed (Linumusitatisimum) oil on libido and semen quality of Nilli-Ravi buffalo bulls. METHODS: In this study, 12 adult healthy bulls kept at the Semen Production Unit, Qadirabad district Sahiwal, were used. These bulls were divided into three equal groups, A, B and C. Group A was kept as control, while in groups B and C supplementation of feed was provided by using flaxseed oil @125 ml/day and 250 ml/day,respectively for 12 weeks...
2016: Journal of Animal Science and Technology
https://www.readbyqxmd.com/read/27275107/natural-cures-for-breast-cancer-treatment
#4
Munazza Shareef, Muhammad Aqeel Ashraf, Maliha Sarfraz
For centuries, herbs and plants have been used for medicinal purposes and as food as well. This review concerns about different types of plants that retain the immune stimulating and anti-tumor properties. Large variety of active phytochemicals such as carotenoids, flavonoids, ligands, polyphenolics, terpenoids, sulfides, lignans and plant sterols has been identified in different types of herbs. These phytochemicals have different mechanisms of action. They either stimulate the protective enzyme like glutathione transferase or prevent the cell proliferation...
May 2016: Saudi Pharmaceutical Journal: SPJ: the Official Publication of the Saudi Pharmaceutical Society
https://www.readbyqxmd.com/read/27136019/effects-of-flaxseed-and-chia-seed-on-ruminal-fermentation-nutrient-digestibility-and-long-chain-fatty-acid-flow-in-a-dual-flow-continuous-culture-system
#5
L G Silva, J Bunkers, E M Paula, T Shenkoru, Y Yeh, B Amorati, D Holcombe, A P Faciola
Flaxseed (FS) and chia seed (CS) are oilseeds rich in omega-3 fatty acids, which may change meat and milk composition when added to ruminants' diets and may have health benefits for humans. Literature on the effects of CS supplementation on ruminal metabolism is nonexistent. A dual-flow continuous culture fermenter system consisting of 6 fermenters was used to assess the effect of FS and CS supplementation in an alfalfa hay-based diet on ruminal fermentation, nutrient digestibility, microbial protein synthesis, and long-chain fatty acid flow...
April 2016: Journal of Animal Science
https://www.readbyqxmd.com/read/26970925/recombinant-endo-mannanase-manb-1601-production-using-agro-industrial-residues-development-of-economical-medium-and-application-in-oil-extraction-from-copra
#6
Gaurav Singh Kaira, Deepesh Panwar, Mukesh Kapoor
Expression of pRSETA manb-1601 construct in Hi-Control Escherichia coli BL21 (DE3) cells improved recombinant endo-mannanase (ManB-1601) production by 2.73-fold (1821±100U/ml). A low-cost, agro-industrial residue supplemented industrial medium for enhanced and economical production of ManB-1601 was developed in two mutual phases. Phase-I revealed the potential of various pre- (induction time: 5h, induction mode: lactose 0.5mM) and post-induction [peptone supplementation: 0.94%(w/v), glycerol 0.123%(v/v)] parameters for enhanced production of ManB-1601 and resulted in 4...
June 2016: Bioresource Technology
https://www.readbyqxmd.com/read/26854452/flax-seed-oil-inhibits-metastatic-melanoma-and-reduces-lung-tumor-formation-in-mice
#7
Jian Han, Shan-Shan Lu, Zhi-Jie Wang, You-Lin Li
PURPOSE: Cancer is one of the leading causes of mortality worldwide. Tumor cells circulating in the blood evidence the migration of tumor from the site of origin to another site leading to the formation of new metastatic lesion and establishment of metastatic tumors. In the present study, cultured metastatic tumor cells were injected into the C57BL/6 mice through tail-vein injection (TVI) and the anti-metastatic properties of flax seed oil (FSO) were evaluated. METHODS: Pre-administration of FSO in a dose of 0...
November 2015: Journal of B.U.ON.: Official Journal of the Balkan Union of Oncology
https://www.readbyqxmd.com/read/26793308/consumption-of-buglossoides-arvensis-seed-oil-is-safe-and-increases-tissue-long-chain-n-3-fatty-acid-content-more-than-flax-seed-oil-results-of-a-phase-i-randomised-clinical-trial
#8
Natalie Lefort, Rémi LeBlanc, Marie-Andrée Giroux, Marc E Surette
Enrichment of tissues with ≥20-carbon n-3 PUFA like EPA is associated with positive cardiovascular outcomes. Stearidonic acid (SDA; 18 : 4n-3) and α-linolenic acid (ALA; 18 : 3n-3) are plant-derived dietary n-3 PUFA; however, direct comparisons of their impact on tissue n-3 PUFA content are lacking. Ahiflower(®) oil extracted from Buglossoides arvensis seeds is the richest known non-genetically modified source of dietary SDA. To investigate the safety and efficacy of dietary Ahiflower oil, a parallel-group, randomised, double-blind, comparator-controlled phase I clinical trial was performed...
2016: Journal of Nutritional Science
https://www.readbyqxmd.com/read/26779302/emulsions-made-of-oils-from-seeds-of-gm-flax-protect-v79-cells-against-oxidative-stress
#9
Katarzyna Skorkowska-Telichowska, Karolina Hasiewicz-Derkacz, Tomasz Gębarowski, Anna Kulma, Helena Moreira, Kamil Kostyn, Katarzyna Gębczak, Anna Szyjka, Wioleta Wojtasik, Kazimierz Gąsiorowski
Polyunsaturated fatty acids, sterols, and hydrophilic phenolic compounds are components of flax oil that act as antioxidants. We investigated the impact of flax oil from transgenic flax in the form of emulsions on stressed Chinese hamster pulmonary fibroblasts. We found that the emulsions protect V79 cells against the H2O2 and the effect is dose dependent. They reduced the level of intracellular reactive oxygen species and protected genomic DNA against damage. The rate of cell proliferation increased upon treatment with the emulsions at a low concentration, while at a high concentration it decreased significantly, accompanied by increased frequency of apoptotic cell death...
2016: Oxidative Medicine and Cellular Longevity
https://www.readbyqxmd.com/read/26275932/fish-oil-and-flax-seed-oil-supplemented-diets-increase-ffar4-expression-in-the-rat-colon
#10
Ameneh Cheshmehkani, Ilya S Senatorov, Praveen Kandi, Monalisa Singh, April Britt, Renée Hayslett, Nader H Moniri
BACKGROUND AND OBJECTIVE: Omega-3 fatty acids, such as α-linolenic acid (ALA), eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA), are polyunsaturated fatty acids (PUFA) that have long been associated with anti-inflammatory activity and general benefit toward human health. Over the last decade, the identification of a family of cell-surface G protein-coupled receptors that bind and are activated by free-fatty acids, including omega-3 fatty acids, suggest that many effects of PUFA are receptor-mediated...
October 2015: Inflammation Research: Official Journal of the European Histamine Research Society ... [et Al.]
https://www.readbyqxmd.com/read/26123633/natural-phenolics-greatly-increase-flax-linum-usitatissimum-oil-stability
#11
Karolina Hasiewicz-Derkacz, Anna Kulma, Tadeusz Czuj, Anna Prescha, Magdalena Żuk, Magdalena Grajzer, Marcin Łukaszewicz, Jan Szopa
BACKGROUND: Flaxseed oil is characterized by high content of essential polyunsaturated fatty acids (PUFA) promoted as a human dietary supplement protecting against atherosclerosis. The disadvantage of the high PUFA content in flax oil is high susceptibility to oxidation, which can result in carcinogenic compound formation. Linola flax cultivar is characterized by high linoleic acid content in comparison to traditional flax cultivars rich in linolenic acid. The changes in fatty acid proportions increase oxidative stability of Linola oil and broaden its use as an edible oil for cooking...
2015: BMC Biotechnology
https://www.readbyqxmd.com/read/26123542/heterologous-expression-of-flax-phospholipid-diacylglycerol-cholinephosphotransferase-pdct-increases-polyunsaturated-fatty-acid-content-in-yeast-and-arabidopsis-seeds
#12
Aruna D Wickramarathna, Rodrigo M P Siloto, Elzbieta Mietkiewska, Stacy D Singer, Xue Pan, Randall J Weselake
BACKGROUND: Flax (Linum usitatissimum L.) is an agriculturally important crop with seed oil enriched in α-linolenic acid (18:3 (cisΔ9, 12, 15); ALA). This polyunsaturated fatty acid (PUFA) is the major determinant for the quality of flax seed oil in food, nutraceuticals and industrial applications. The recently identified enzyme: phosphatidylcholine diacylglycerol cholinephosphotransferase (PDCT), catalyzes the interconversion between phosphatidylcholine (PC) and diacylglycerol (DAG), and has been shown to play an important role in PUFA accumulation in Arabidopsis thaliana seeds...
2015: BMC Biotechnology
https://www.readbyqxmd.com/read/26055703/in-vivo-and-in-vitro-evidence-for-biochemical-coupling-of-reactions-catalyzed-by-lysophosphatidylcholine-acyltransferase-and-diacylglycerol-acyltransferase
#13
Xue Pan, Guanqun Chen, Michael Kazachkov, Michael S Greer, Kristian Mark P Caldo, Jitao Zou, Randall J Weselake
Seed oils of flax (Linum usitatissimum L.) and many other plant species contain substantial amounts of polyunsaturated fatty acids (PUFAs). Phosphatidylcholine (PC) is the major site for PUFA synthesis. The exact mechanisms of how these PUFAs are channeled from PC into triacylglycerol (TAG) needs to be further explored. By using in vivo and in vitro approaches, we demonstrated that the PC deacylation reaction catalyzed by the reverse action of acyl-CoA:lysophosphatidylcholine acyltransferase (LPCAT) can transfer PUFAs on PC directly into the acyl-CoA pool, making these PUFAs available for the diacylglycerol acyltransferase (DGAT)-catalyzed reaction for TAG production...
July 17, 2015: Journal of Biological Chemistry
https://www.readbyqxmd.com/read/25977051/effect-directed-analysis-of-cold-pressed-hemp-flax-and-canola-seed-oils-by-planar-chromatography-linked-with-bio-assays-and-mass-spectrometry
#14
Sue-Siang Teh, Gertrud E Morlock
Cold-pressed hemp, flax and canola seed oils are healthy oils for human consumption as these are rich in polyunsaturated fatty acids and bioactive phytochemicals. However, bioactive information on the food intake side is mainly focused on target analysis. For more comprehensive information with regard to effects, single bioactive compounds present in the seed oil extracts were detected by effect-directed assays, like bioassays or an enzymatic assay, directly linked with chromatography and further characterized by mass spectrometry...
November 15, 2015: Food Chemistry
https://www.readbyqxmd.com/read/25870713/a-review-of-characterization-of-tocotrienols-from-plant-oils-and-foods
#15
REVIEW
Haseeb Ahsan, Amjid Ahad, Waseem A Siddiqui
Tocotrienols, members of the vitamin E family, are natural compounds found in a number of vegetable oils, wheat germ, barley and certain types of nuts and grains. Vegetable oils provide the best sources of these vitamin E forms, particularly palm oil and rice bran oil contain higher amounts of tocotrienols. Other sources of tocotrienols include grape fruit seed oil, oats, hazelnuts, maize, olive oil, buckthorn berry, rye, flax seed oil, poppy seed oil and sunflower oil. Tocotrienols are of four types, viz. alpha (α), beta (β), gamma (γ) and delta (δ)...
April 2015: Journal of Chemical Biology
https://www.readbyqxmd.com/read/25753491/development-and-validation-of-an-efficient-ultrasound-assisted-extraction-of-phenolic-compounds-from-flax-linum-usitatissimum-l-seeds
#16
Cyrielle Corbin, Thibaud Fidel, Emilie A Leclerc, Esmatullah Barakzoy, Nadine Sagot, Annie Falguiéres, Sullivan Renouard, Jean-Philippe Blondeau, Clotilde Ferroud, Joël Doussot, Eric Lainé, Christophe Hano
Flaxseed accumulates in its seedcoat a macromolecular complex composed of lignan (secoisolariciresinol diglucoside, SDG), flavonol (herbacetin diglucoside, HDG) and hydroxycinnamic acids (p-couramic, caffeic and ferulic acid glucosides). Their antioxidant and/or cancer chemopreventive properties support their interest in human health and therefore, the demand for their extraction. In the present study, ultrasound-assisted extraction (UAE) of flaxseed phenolic compounds was investigated. Scanning Electron Microscopy imaging and histochemical analysis revealed the deep alteration of the seedcoat ultrastructure and the release of the mucilage following ultrasound treatment...
September 2015: Ultrasonics Sonochemistry
https://www.readbyqxmd.com/read/25748113/qtl-for-fatty-acid-composition-and-yield-in-linseed-linum-usitatissimum-l
#17
Santosh Kumar, Frank M You, Scott Duguid, Helen Booker, Gordon Rowland, Sylvie Cloutier
The combined SSR-SNP map and 20 QTL for agronomic and quality traits will assist in marker assisted breeding as well as map-based cloning of key genes in linseed. Flax is an important nutraceutical crop mostly because it is a rich source of omega-3 fatty acids and antioxidant compounds. Canada is the largest producer and exporter of oilseed flax (or linseed), creating a growing need to improve crop productivity and quality. In this study, a genetic map was constructed based on selected 329 single nucleotide polymorphic markers and 362 simple sequence repeat markers using a recombinant inbred line population of 243 individuals from a cross between the Canadian varieties CDC Bethune and Macbeth...
May 2015: TAG. Theoretical and Applied Genetics. Theoretische und Angewandte Genetik
https://www.readbyqxmd.com/read/25740909/flaxseed-consumption-may-reduce-blood-pressure-a-systematic-review-and-meta-analysis-of-controlled-trials
#18
REVIEW
Saman Khalesi, Christopher Irwin, Matt Schubert
BACKGROUND: High blood pressure is a major health burden positively associated with the risk of cardiovascular disease and other chronic diseases. Flaxseed is a rich dietary source of α-linolenic acid, lignans, and fiber, with a number of positive health benefits on blood pressure. OBJECTIVE: The purpose of this study was to clarify the effect of flaxseed consumption on blood pressure. Further, the influence of baseline blood pressure, type of flaxseed supplementation, and duration of flaxseed supplementation on blood pressure was explored...
April 2015: Journal of Nutrition
https://www.readbyqxmd.com/read/25536541/co-administration-of-a-probiotic-strain-lactobacillus-plantarum-ls-07-ccm7766-with-prebiotic-inulin-alleviates-the-intestinal-inflammation-in-rats-exposed-to-n-n-dimethylhydrazine
#19
Jana Štofilová, Viktória Szabadosová, Gabriela Hrčková, Rastislav Salaj, Izabela Bertková, Emília Hijová, Ladislav Strojný, Alojz Bomba
The aim of this study was to determine the anti-inflammatory effects of preventive administration of a probiotic strain Lactobacillus plantarum LS/07 CCM7766 alone or in combination with prebiotic inulin or with flax-seed oil in the gut of rats, which developed chronic inflammation following administration of the pro-carcinogen N,N-dimethylhydrazine (DMH). After 28weeks administration of probiotic/prebiotic-containing diet, rats were killed and their colons were examined by immunohistological criteria, whereas cytokines were determined in the jejunal mucosa...
February 2015: International Immunopharmacology
https://www.readbyqxmd.com/read/25534638/an-improved-method-for-extraction-of-high-quality-total-rna-from-oil-seeds
#20
Azadeh Rayani, Fatemeh Dehghan Nayeri
Seeds of oilseed plants that contain large amounts of oil, polysaccharides, proteins and polyphenols are not amenable to conventional RNA isolation protocols. The presence of these substances affects the quality and quantity of isolated nucleic acids. Here, a rapid and efficient RNA isolation protocol that, in contrast to other methods tested, allows high purify, integrity and yield of total RNA from seeds of sesame, corn, sunflower, flax and rapeseed was developed. The average yields of total RNA from 70 mg oil seeds ranged from 84 to 310 µg with A260/A280 between 1...
April 2015: Biotechnology Letters
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