keyword
https://read.qxmd.com/read/38646564/combined-effect-of-brazilin-rich-extract-and-lawsone-methyl-ether-against-infection-causing-bacteria
#1
JOURNAL ARTICLE
Nilesh Nirmal, Pankaj Koirala, Anandu Chandra Khanashyam, Pharkphoom Panichayupakaranant, Abdi Wira Septama
Bacterial contamination and infection widely affect the food, pharmaceutical and biomedical industries. Additionally, these bacteria developed resistance to synthetic antibiotics causing public health danger, globally. Natural plant extracts (NPE) are suitable alternatives to synthetic antibiotics to tackle antimicrobial resistance problems. Furthermore, a blend or combination of different NPEs exerts a wide spectrum of antimicrobial activity. Therefore, the combined effect of brazilin-rich extract (BRE) and lawsome methyl ether (LME) against infection-causing common bacteria were evaluated...
June 2024: Saudi Journal of Biological Sciences
https://read.qxmd.com/read/38644387/antibacterial-and-antibiofilm-activities-of-iodinated-hydrocarbons-against-vibrio-parahaemolyticus-and-staphylococcus-aureus
#2
JOURNAL ARTICLE
Oluwatosin Oluwaseun Faleye, Olajide Sunday Faleye, Jin-Hyung Lee, Jintae Lee
Food-related illnesses have become a growing public concern due to their considerable socioeconomic and medical impacts. Vibrio parahaemolyticus and Staphylococcus aureus have been implicated as causative organisms of food-related infections and poisoning, and both can form biofilms which confer antibiotic resistance. Hence, the need for continuous search for compounds with antibiofilm and antivirulence properties. In this study, 22 iodinated hydrocarbons were screened for their antibiofilm activity, and of these, iodopropynyl butylcarbamate (IPBC) was found to effectively control biofilm formation of both pathogens with a MIC of 50 µg/mL which was bactericidal to V...
April 22, 2024: Scientific Reports
https://read.qxmd.com/read/38640320/antibiotic-susceptibility-of-methicillin-resistant-staphylococcus-aureus-mrsa-strains-isolated-at-tertiary-care-hospital-in-riyadh-saudi-arabia
#3
JOURNAL ARTICLE
Dalia Al-Sarar, Ihab M Moussa, Abdulkarim Alhetheel
Staphylococcus aureus is an important human pathogen that has a major impact on public health. The objective of the present work was to determine the prevalence and the pattern of antibiotic susceptibility in S aureus (MRSA) isolates from the King Khalid University Hospital (KKUH) in Riyadh, Saudi Arabia. The isolates were collected from different body sites of infection and the antibiotic susceptibility was confirmed on the Vitek 2 system. A total of 371 MRSA isolates from clinical samples were received over a 12-month period from January 2021 to December 2021...
April 19, 2024: Medicine (Baltimore)
https://read.qxmd.com/read/38637091/enterotoxigenic-staphylococcus-aureus-in-brazilian-artisanal-cheeses-occurrence-counts-phenotypic-and-genotypic-profiles
#4
JOURNAL ARTICLE
Larissa P Margalho, Juliana S Graça, Bruna A Kamimura, Sarah H I Lee, Héctor D S Canales, Alexandra I A Chincha, Magdevis Y R Caturla, Ramon P Brexó, Aline Crucello, Verônica O Alvarenga, Adriano G Cruz, Carlos Augusto F Oliveira, Anderson S Sant'Ana
The present study aimed to assess the occurrence and counts of Staphylococcus aureus in Brazilian artisanal cheeses (BAC) produced in five regions of Brazil: Coalho and Manteiga (Northeast region); Colonial and Serrano (South); Caipira (Central-West); Marajó (North); and Minas Artisanal cheeses, from Araxá, Campos das Vertentes, Cerrado, Serro and Canastra microregions (Southeast). The resistance to chlorine-based sanitizers, ability to attach to stainless steel surfaces, and antibiogram profile of a large set of S...
August 2024: Food Microbiology
https://read.qxmd.com/read/38636748/3d-printed-piezocatalytic-hydrogels-for-effective-antibacterial-treatment-of-infected-wounds
#5
JOURNAL ARTICLE
Yun Chen, Chen Wang, Zhiyuan Zhang, Fangzheng Yu, Yu Wang, Jianqiang Ding, Zheng Zhao, Yichao Liu
Bacterial-infected wound repair has become a significant public health concern. This study developed a novel 3D-printed piezocatalytic SF-MA/PEGDA/Ag@BT (SPAB) hydrogels were fabricated by using digital light processing. These hydrogels exhibited high consistency, mechanical properties and good biocompatibility. Besides, the SPAB hydrogels exhibited excellent piezocatalytic performance and thus could induce piezoelectric polarization under ultrasound to generate reactive oxygen species (ROS). The SPAB hydrogels possessed an antibacterial rate of 99...
April 16, 2024: International Journal of Biological Macromolecules
https://read.qxmd.com/read/38633890/assessing-the-microbial-diversity-and-proximate-composition-of-smoked-fermented-bushmeat-from-four-different-bushmeat-samples
#6
JOURNAL ARTICLE
Afia Sakyiwaa Amponsah, Gloria Mathanda Ankar-Brewoo, Herman Erick Lutterodt, Isaac Williams Ofosu
The ever-increasing demand for wildlife-derived raw or processed meat commonly known as bushmeat, has been identified as one of the critical factors driving the emergence of infectious diseases. This study focused on examining the bacterial community composition of smoked and fermented bushmeats, specifically grasscutter, rat, rabbit, and mona monkey. The analysis involved exploring 16Sr RNA amplicon sequences isolated from bushmeat using QIIME2. Microbiome profiles and their correlation with proximate components (PLS regression) were computed in STAMP and XLSTAT, respectively...
2024: Biotechnologia
https://read.qxmd.com/read/38633471/community-acquired-multidrug-resistant-pneumonia-bacteraemia-and-infective-endocarditis-a-case-report
#7
Basavaraj Jatteppanavar, Arnab Choudhury, Prasan Kumar Panda, Mukesh Bairwa
BACKGROUND: The prevalence of multidrug-resistant (MDR) bacteria has increased globally, with extensive drug-resistant (XDR) bacteria posing a threat to patients. CASE SUMMARY: This case report describes a young man admitted for suspected tropical fever infections who experienced rapid deterioration in health. Despite negative results for tropical fever infections, he had neutrophilic leucocytosis, acute kidney injury, and chest imaging findings suggestive of bilateral consolidations...
March 9, 2024: World Journal of Critical Care Medicine
https://read.qxmd.com/read/38633196/screening-of-antibiogram-virulence-factors-and-biofilm-production-of-staphylococcus-aureus-and-the-bio-control-role-of-some-probiotics-as-alternative-antibiotics
#8
JOURNAL ARTICLE
Aya R Mohammed, Esmat I El-Said, Salah F Abd ElAal, Rania M Kamal
BACKGROUND: Food safety is a serious challenge in the face of increasing population and diminishing resources. Staphylococcus aureus is a critical foodborne pathogen characterized by its capability to secret a diverse range of heat-resistant enterotoxins. Antibiotic usage in dairy herds resulted in the occurrence of antimicrobial resistance (AMR) patterns among bacterial species, which were consequently transmitted to humans via dairy products. Lactic acid bacteria (LAB) produce bacteriocins, which provide an excellent source of natural antimicrobials with the further advantage of being environmentally friendly and safe...
January 2024: Open Veterinary Journal
https://read.qxmd.com/read/38633191/individual-genomic-loci-transcript-level-and-biochemical-profile-of-immune-and-antioxidant-markers-associated-with-genetically-identified-bacterial-mastitis-in-shami-goats-in-egypt
#9
JOURNAL ARTICLE
Eman Ebissy, Asmaa Darwish, Amani A Hafez, Ahmed Ateya, Ahmed El-Sayed
BACKGROUND: Mastitis in goats is unquestionably a grave concern, with far-reaching implications for both animal well-being and productivity, while also presenting a potential threat to public health. AIM: The study aimed to compare culture methods and multiplex PCR (m-PCR) in the detection of the most three common mastitis-causing pathogens ( Staphylococcus aureus , Escherichia coli , and Streptococcus spp.) and investigate the gene expression, single nucleotide polymorphisms (SNPs), serum concentrations of immunological and antioxidant indicators linked to mastitis in Shami goats...
January 2024: Open Veterinary Journal
https://read.qxmd.com/read/38633161/bacteriological-evaluation-and-advanced-sybr-green-multiplex-real-time-pcr-assay-for-detection-of-minced-meat-adulteration
#10
JOURNAL ARTICLE
Soad H El-Sheikh, Reham M Abdel Whab, Rania A ElDaly, Mona T Raslan, Hanan A Fahmy, Azza S El-Demerdash
BACKGROUND: Minced meat is a valuable source of nutrients, but it is vulnerable to contamination by microorganisms commonly present in the environment. In addition, there is a risk of adulteration with cheaper meat sources, which can be harmful to consumers. AIM: It is crucial to identify meat adulteration with distinct microbiological analysis for legal, economic, religious, and public health purposes. METHODS: A total of 100 minced meat samples were collected from several markets in Sharkia Governorate, Egypt...
January 2024: Open Veterinary Journal
https://read.qxmd.com/read/38630391/burden-of-antimicrobial-resistance-among-women-with-post-partum-infections-in-low-middle-income-countries-a-systematic-review
#11
REVIEW
Caterina Monari, Lorenzo Onorato, Nicola Coppola, Mario C B Raviglione, Giorgia Gon
BACKGROUND: Due to the rising incidence of multidrug-resistant (MDR) pathogens, especially in Low-Middle-Income Countries (LMIC), post-partum infections represent a significant treatment challenge. METHODS: We performed a systematic review of the literature from January 2005 to February 2023 to quantify the frequency of maternal post-partum infections due to MDR pathogens in LMICs, focusing on methicillin-resistant Staphylococcus aureus (MRSA) and/or extended-spectrum beta-lactamase (ESBL)-producing Enterobacterales...
April 17, 2024: Journal of Epidemiology and Global Health
https://read.qxmd.com/read/38629875/employment-of-mastoparan-like-peptides-to-prevent-staphylococcus-aureus-associated-with-bovine-mastitis
#12
JOURNAL ARTICLE
Raquel M Q Orozco, Karen G N Oshiro, Ingrid B Pinto, Danieli F Buccini, Claudiane V Almeida, Valentina Nieto Marin, Camila Maurmann de Souza, Maria L R Macedo, Marlon H Cardoso, Octávio L Franco
Bovine mastitis is a frequent infection in lactating cattle, causing great economic losses. Staphylococcus aureus represents the main etiological agent, which causes recurrent and persistent intramammary infections because conventional antibiotics are ineffective against it. Mastoparan-like peptides are multifunctional molecules with broad antimicrobial potential, constituting an attractive alternative. Nevertheless, their toxicity to host cells has hindered their therapeutic application. Previously, our group engineered three mastoparan-L analogs, namely mastoparan-MO, mastoparan-R1, and [I5 , R8 ] MP, to improve cell selectivity and potential...
April 17, 2024: Journal of Bacteriology
https://read.qxmd.com/read/38628759/on-the-antimicrobial-properties-and-endurance-of-eugenol-and-2-phenylphenol-functionalized-sol-gel-coatings
#13
JOURNAL ARTICLE
Ana Suárez-Vega, Gemma Berriozabal, Juan Perez de Iriarte, Jaione Lorenzo, Noelia Álvarez, Santiago Dominguez-Meister, Sara Insausti, Edurne Rujas, Jose L Nieva, Marta Brizuela, Iñigo Braceras
Preventing microbiological surface contamination in public spaces is nowadays of high priority. The proliferation of a microbial infection may arise through air, water, or direct contact with infected surfaces. Chemical sanitization is one of the most effective approaches to avoid the proliferation of microorganisms. However, extended contact with chemicals for cleaning purposes such as chlorine, hydrogen peroxide or ethanol may lead to long-term diseases as well as drowsiness or respiratory issues, not to mention environmental issues associated to their use...
April 30, 2024: Heliyon
https://read.qxmd.com/read/38627609/occurrence-antimicrobial-susceptibility-and-resistance-genes-of-staphylococcus-aureus-in-milk-and-milk-products-in-the-arsi-highlands-of-ethiopia
#14
JOURNAL ARTICLE
Abiot Deddefo, Gezahegne Mamo, Minda Asfaw, Adem Edao, Adem Hiko, Dereje Fufa, Mohammed Jafer, Melaku Sombo, Kebede Amenu
BACKGROUND: In Ethiopia, milk production and handling practices often lack proper hygiene measures, leading to the potential contamination of milk and milk products with Staphylococcus aureus (S. aureus), including methicillin-resistant strains, posing significant public health concerns. This study aimed to investigate the occurrence, antimicrobial susceptibility profiles and presence of resistance genes in S. aureus strains isolated from milk and milk products. METHODS: A cross-sectional study was conducted in the Arsi highlands, Oromia, Ethiopia from March 2022 to February 2023...
April 16, 2024: BMC Microbiology
https://read.qxmd.com/read/38623408/corneal-deposits-a-presentation-of-arthrobacter-keratitis
#15
Joanna S Saade, Baha' N Noureddine, Hanadi A Ibrahim
INTRODUCTION: Infectious keratitis, an inflammatory condition of the cornea, poses a significant public health concern globally. Bacterial keratitis, the most common type, primarily involves Staphylococcus aureus and Pseudomonas aeruginosa . Timely diagnosis and treatment are crucial to prevent vision loss. CASE PRESENTATION: This case report presents a 78-year-old male patient with a burning sensation persisting for 1 week. The patient was diagnosed with keratitis caused by Arthrobacter, a Gram-positive coccobacillus commonly found in the environment...
2024: Case Reports in Ophthalmology
https://read.qxmd.com/read/38621246/infectious-diseases-what-you-may-have-missed-in-2023
#16
JOURNAL ARTICLE
Amena Alhammadi, Rasha Alshawaf, Swati Chavda, Sonya Ramondino, Mindy Schuster
In 2023, published research on COVID-19 remains prominent. The aim of this article is to highlight important developments in infectious disease evidence unrelated to COVID-19 that were published in 2023. The literature was screened for sound new evidence relevant to internal medicine specialists and subspecialists whose focus of practice is not infectious diseases. The highlighted publications relate to various organisms and patient populations. One article provides insight into the updated guidelines for the diagnosis and management of infective endocarditis...
April 16, 2024: Annals of Internal Medicine
https://read.qxmd.com/read/38616592/antibiotic-susceptibility-of-staphylococcus-aureus-with-vana-and-meca-genes
#17
JOURNAL ARTICLE
Lata Ghimire, Megha Raj Banjara, Abdelkodose Mh Abdulla
BACKGROUND: Staphylococcus aureus (S.aureus) is an emerging antibiotic resistant bacterium responsible for various infections in human. Resistance to methicillin and vancomycin are of prime concern in S. aureus. The study aims to determine the minimum inhibitory concentration (MIC) of Vancomycin and evaluate the existence of mecA and vanA genes, associated with antibiotic resistance. METHODS: Clinical specimens from three Kathmandu hospitals were processed and S...
March 31, 2024: Journal of Nepal Health Research Council
https://read.qxmd.com/read/38612142/nanoparticles-partially-restore-bacterial-susceptibility-to-antibiotics
#18
JOURNAL ARTICLE
Nina Bogdanchikova, Roberto Luna Vazquez-Gomez, Ekaterina Nefedova, Diana Garibo, Alexey Pestryakov, Evgenii Plotnikov, Nikolay N Shkil
The growing resistance of bacteria to antibiotics is one of the main public health problems nowadays. The influence of silver nanoparticle (AgNP) pretreatment of 220 cows with mastitis on the susceptibility of Staphylococcus epidermidis bacteria to 31 antibiotics was studied. The obtained results were compared with the previous results for Escherichia coli , Streptococcus dysgalactiae , and Staphylococcus aureus . For all four bacteria, an increase in susceptibility (9.5-21.2%) to 31 antibiotics after cow treatment with AgNPs was revealed, while after first-line antibiotic drug treatment as expected, the susceptibility decreased (11...
April 2, 2024: Materials
https://read.qxmd.com/read/38611812/exploration-of-the-antibacterial-and-anti-inflammatory-activity-of-a-novel-antimicrobial-peptide-brevinin-1bw
#19
JOURNAL ARTICLE
Zhizhi Chen, Lei Wang, Dongxia He, Qi Liu, Qinqin Han, Jinyang Zhang, A-Mei Zhang, Yuzhu Song
Antibiotic resistance has emerged as a grave threat to global public health, leading to an increasing number of treatment failures. Antimicrobial peptides (AMPs) are widely regarded as potential substitutes for traditional antibiotics since they are less likely to induce resistance when used. A novel AMP named Brevinin-1BW (FLPLLAGLAASFLPTIFCKISRKC) was obtained by the Research Center of Molecular Medicine of Yunnan Province from the skin of the Pelophylax nigromaculatus . Brevinia-1BW had effective inhibitory effects on Gram-positive bacteria, with a minimum inhibitory concentration (MIC) of 3...
March 29, 2024: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://read.qxmd.com/read/38608638/copper-selenide-nanosheets-with-photothermal-therapy-related-properties-and-multienzyme-activity-for-highly-effective-eradication-of-drug-resistance
#20
JOURNAL ARTICLE
Yongsheng Li, Jiajia Yu, Wei Zhang, Jie Shan, Hongrang Chen, Yan Ma, Xianwen Wang
Bacterial infections are among the most significant causes of death in humans. Chronic misuse or uncontrolled use of antibiotics promotes the emergence of multidrug-resistant superbugs that threaten public health through the food chain and cause environmental pollution. Based on the above considerations, copper selenide nanosheets (CuSe NSs) with photothermal therapy (PTT)- and photodynamic therapy (PDT)-related properties have been fabricated. These CuSe NSs possess enhanced PDT-related properties and can convert O2 into highly toxic reactive oxygen species (ROS), which can cause significant oxidative stress and damage to bacteria...
March 30, 2024: Journal of Colloid and Interface Science
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