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https://www.readbyqxmd.com/read/28193163/prevalence-and-clinical-presentation-of-rickettsia-coxiella-leptospira-bartonella-and-chikungunya-virus-infections-among-hospital-based-febrile-patients-from-december-2008-to-november-2009-in-bangladesh
#1
Labib Imran Faruque, Rashid Uz Zaman, Emily S Gurley, Robert F Massung, A S M Alamgir, Renee L Galloway, Ann M Powers, Ying Bai, Michael Kosoy, William L Nicholson, Mahmudur Rahman, Stephen P Luby
BACKGROUND: We conducted a study to identify Rickettsia, Coxiella, Leptospira, Bartonella, and Chikungunya virus infections among febrile patients presenting at hospitals in Bangladesh. METHODS: We collected blood samples from patients at six tertiary hospitals from December 2008 to November 2009 and performed laboratory tests at the United States Centers for Disease Control and Prevention (CDC). RESULTS: Out of 720 enrolled patients, 263 (37%) were infected with Rickettsia; 132 patients had immunofluorescence antibody titer >64 against spotted fever, 63 patients against scrub typhus fever and 10 patients against typhus fever...
February 13, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28188085/species-of-ticks-and-carried-pathogens-in-owned-dogs-in-spain-results-of-a-one-year-national-survey
#2
Agustín Estrada-Peña, Xavier Roura, Angel Sainz, Guadalupe Miró, Laia Solano-Gallego
This study presents the results of a national survey in Spain on the distribution of ticks on owned dogs, their phenology and the associated pathogens over one year. In the study, 1628 adult ticks were collected on 660 dogs presented to 26 veterinary practices, of which 507 dogs (76.8%) carried at least one adult tick. The primary species of ticks were Rhipicephalus sanguineus s.l. (53%), Dermacentor reticulatus (9%), Ixodes ricinus (9%), and I. hexagonus (4%). Parasitism by two species of these ticks was rare...
February 3, 2017: Ticks and Tick-borne Diseases
https://www.readbyqxmd.com/read/28169507/predictive-factors-for-fatal-tick-borne-spotted-fever-in-brazil
#3
S V de Oliveira, M C A Willemann, G S Gazeta, R N Angerami, R Gurgel-Gonçalves
In Brazil, two pathogenic Rickettsia species have been identified causing tick-borne spotted fever (SF). The aetiological agent Rickettsia rickettsii causes serious illness, particularly in the south-eastern region of the country. Moreover, the Rickettsia sp. strain Atlantic Rainforest cause milder clinical manifestations in south-eastern, south and north-east regions. This study has sought to analyse predictive factors for fatal SF. A case-control study was performed using disease notification records in Brazil...
February 7, 2017: Zoonoses and Public Health
https://www.readbyqxmd.com/read/28162961/undifferentiated-tropical-febrile-illness-in-cordoba-colombia-not-everything-is-dengue
#4
Salim Mattar, Vaneza Tique, Jorge Miranda, Eney Montes, Denisses Garzon
In Colombia, undifferentiated tropical febrile illness (UTFI) are frequent and of considerable concern. They also share many clinical features. Between 2012 and 2013 in an endemic tropical area of Cordoba, Colombia, we conducted a prospective study to establish an etiological diagnosis of UTFI. Using diagnostic tests for dengue, leptospirosis, hantavirus, malaria, rickettsia, brucellosis, hepatitis A and B on 100 patients recruited for the study. We identified 69 patients with presumed UTFI: leptospirosis (n=27), dengue (n=26), hantavirus infection (n=4), malaria (n=4), rickettsial infection (n=2), hepatitis A (n=1), and brucellosis (n=1); no hepatitis B cases were detected...
February 2, 2017: Journal of Infection and Public Health
https://www.readbyqxmd.com/read/28155284/molecular-surveillance-of-spotted-fever-group-rickettsioses-in-wildlife-and-detection-of-i-rickettsia-sibirica-i-in-a-topi-i-damaliscus-lunatus-i-ssp-i-jimela-i-in-kenya
#5
David Ndeereh, Andrew Thaiyah, Gerald Muchemi, Antoinette A Miyunga
Spotted fever group rickettsioses are a group of tick-borne zoonotic diseases caused by intracellular bacteria of the genus Rickettsia. The diseases are widely reported amongst international travellers returning from most sub-Saharan Africa with fever, yet their importance in local populations largely remains unknown. Although this has started to change and recently there have been increasing reports of the diseases in livestock, ticks and humans in Kenya, they have not been investigated in wildlife. We examined the presence, prevalence and species of Rickettsia present in wildlife in two regions of Kenya with a unique human-wildlife-livestock interface...
January 30, 2017: Onderstepoort Journal of Veterinary Research
https://www.readbyqxmd.com/read/28153052/distribution-and-molecular-characteristics-of-rickettsiae-found-in-ticks-across-central-mongolia
#6
Bazartseren Boldbaatar, Rui-Ruo Jiang, Michael E von Fricken, Sukhbaatar Lkhagvatseren, Pagbajab Nymadawa, Bekhochir Baigalmaa, Ya-Wei Wang, Benjamin D Anderson, Jia-Fu Jiang, Gregory C Gray
BACKGROUND: Little is known regarding tick-borne diseases in Mongolia, despite having 26% of the population still living nomadic pastoral lifestyles. A total of 1497 adult unfed ticks: 261 Ixodes persulcatus, 795 Dermacentor nuttalli, and 441 Hyalomma asiaticum, were collected from three ecologically distinct regions in Central Mongolia. Tick pools (n = 299) containing ~5 ticks each, were tested for Rickettsia and Tick-borne encephalitis virus (TBEV) using nested polymerase chain reaction, reverse transcription-PCR, and quantitative real-time RT-PCR...
February 2, 2017: Parasites & Vectors
https://www.readbyqxmd.com/read/28143697/first-detection-of-tick-borne-pathogens-of-dogs-from-malta
#7
Elaine Licari, Nóra Takács, Norbert Solymosi, Róbert Farkas
The knowledge about the vector-borne infections in domestic dogs has been increasing worldwide. However no studies have been done on hard tick infestation and tick-borne pathogens (TBPs) of dogs present in Malta. Therefore, a total of 99 dogs was selected and inspected between March and July 2013 in 18 urban and 17 rural areas on the islands of Malta and Gozo. All ticks were removed from the dogs and identified. Blood samples were taken and tested for protozoa (Babesia spp. and Hepatozoon spp.) and bacteria (Anaplasma spp...
January 18, 2017: Ticks and Tick-borne Diseases
https://www.readbyqxmd.com/read/28141857/intestinal-parasites-and-vector-borne-pathogens-in-stray-and-free-roaming-cats-living-in-continental-and-insular-greece
#8
Anastasia Diakou, Angela Di Cesare, Paolo Matteo Accettura, Luciano Barros, Raffaella Iorio, Barbara Paoletti, Antonio Frangipane di Regalbono, Lénaïg Halos, Frederic Beugnet, Donato Traversa
This survey investigated the distribution of various intestinal parasites and vector-borne pathogens in stray and free-roaming cats living in four regions of Greece. A total number of one hundred and fifty cats living in three Islands (Crete, Mykonos and Skopelos) and in Athens municipality was established as a realistic aim to be accomplished in the study areas. All cats were examined with different microscopic, serological and molecular assays aiming at evaluating the occurrence of intestinal parasites, and exposure to or presence of vector-borne infections...
January 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28135131/health-survey-of-free-ranging-raccons-procyon-lotor-in-central-park-new-york-new-york-usa-implications-for-human-and-domestic-animal-health
#9
Kimberly L Rainwater, Krysten Marchese, Sally Slavinski, Lee A Humberg, Edward J Dubovi, Jodie A Jarvis, Denise McAloose, Paul P Calle
We conducted health assessments on 113 free-ranging raccoons ( Procyon lotor ) in Central Park, New York City, in February 2010, September 2010, and November 2011 in conjunction with a trap-vaccinate-release program to control a raccoon rabies epizootic. Five individuals were sampled at two time points for 118 raccoon examinations in total. We tested 13 of 13 and 8 of 13 euthanized raccoons for rabies and canine distemper virus, respectively, by antigen testing on brain tissue; all were negative for both viruses...
January 30, 2017: Journal of Wildlife Diseases
https://www.readbyqxmd.com/read/28122249/genetic-diversity-and-molecular-epidemiology-of-anaplasma
#10
REVIEW
Mara Battilani, Stefano De Arcangeli, Andrea Balboni, Francesco Dondi
Anaplasma are obligate intracellular bacteria of cells of haematopoietic origin and are aetiological agents of tick-borne diseases of both veterinary and medical interest common in both tropical and temperate regions. The recent disclosure of their zoonotic potential has greatly increased interest in the study of these bacteria, leading to the recent reorganisation of Rickettsia taxonomy and to the possible discovery of new species belonging to the genus Anaplasma. This review is particularly focused on the common and unique characteristics of Anaplasma marginale and Anaplasma phagocytophilum, with an emphasis on genetic diversity and evolution, and the main distinguishing features of the diseases caused by the different Anaplasma spp...
January 22, 2017: Infection, Genetics and Evolution
https://www.readbyqxmd.com/read/28115672/rickettsia-felis-infection-in-febrile-children-ghana
#11
Peter Sothmann, Christian Keller, Ralf Krumkamp, Benno Kreuels, Cassandra Aldrich, Nimako Sarpong, Stefanie Steierberg, Doris Winter, Kennedy Gyau Boahen, Ellis Owusu-Dabo, Jürgen May, Daniel Eibach
Rickettsial infections are an underrecognized cause of febrile illness in sub-Saharan Africa. To evaluate the epidemiology and clinical features of rickettsial disease in pediatric patients in Ghana, we screened blood samples from febrile children aged less than 15 years presenting to an outpatient department in Ghana's Ashanti Region for the presence of rickettsial DNA. We detected Rickettsia felis in 7/470 (1.5%) blood samples, using two independent real-time polymerase chain reactions. No other Rickettsia species were found...
January 23, 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/28115179/cat-fleas-ctenocephalides-felis-from-cats-and-dogs-in-new-zealand-molecular-characterisation-presence-of-rickettsia-felis-and-bartonella-clarridgeiae-and-comparison-with-australia
#12
COMPARATIVE STUDY
Shona Chandra, Maureen Forsyth, Andrea L Lawrence, David Emery, Jan Šlapeta
The cat flea (Ctenocephalides felis) is the most common flea species parasitising both domestic cats and dogs globally. Fleas are known vectors of zoonotic pathogens such as vector borne Rickettsia and Bartonella. This study compared cat fleas from domestic cats and dogs in New Zealand's North and South Islands to Australian cat fleas, using the mitochondrial DNA (mtDNA) marker, cytochrome c oxidase subunit I and II (cox1, cox2). We assessed the prevalence of Rickettsia and Bartonella using genus specific multiplexed real-time PCR assays...
January 30, 2017: Veterinary Parasitology
https://www.readbyqxmd.com/read/28111714/pyrosequencing-based-assessment-of-bacterial-diversity-in-turkish-rhipicephalus-annulatus-and-dermacentor-marginatus-ticks-acari-ixodidae
#13
Saban Tekin, Scot E Dowd, Marko Davinic, Ahmet Bursali, Adem Keskin
Ticks continue to be a threat to human and animal health in Turkey, as they are considered important vectors of human and animal diseases. The objectives of this investigation are to characterize the microbial communities of two tick species, Rhipicephalus annulatus and Dermacenter marginatus, analyze patterns of co-occurrence among microbial taxa, identify and compare pathogens contributing human diseases, and determine whether avirulent symbionts could exclude human pathogens from tick communities. Furthermore, this study explores a microbiome of the R...
January 22, 2017: Parasitology Research
https://www.readbyqxmd.com/read/28110915/detection-of-rickettsia-hoogstraalii-rickettsia-helvetica-rickettsia-massiliae-rickettsia-slovaca-and-rickettsia-aeschlimannii-in-ticks-from-sardinia-italy
#14
Valentina Chisu, Hamza Leulmi, Giovanna Masala, Mariano Piredda, Cipriano Foxi, Philippe Parola
Tick-borne diseases represent a large proportion of infectious diseases that have become a world health concern. The presence of Rickettsia spp. was evaluated by standard PCR and sequencing in 123 ticks collected from several mammals and vegetation in Sardinia, Italy. This study provides the first evidence of the presence of Rickettsia hoogstralii in Haemaphysalis punctata and Haemaphysalis sulcata ticks from mouflon and Rickettsia helvetica in Ixodes festai ticks from hedgehog. In addition, Rickettsia massiliae, Rickettsia slovaca and Rickettsia aeschlimannii were detected in Rhipicephalus sanguineus, Dermacentor marginatus and Hyalomma marginatum marginatum ticks from foxes, swine, wild boars, and mouflon...
December 15, 2016: Ticks and Tick-borne Diseases
https://www.readbyqxmd.com/read/28097845/-fatal-case-of-rickettsiosis-in-a-toddler-from-southeastern-mexico
#15
César Lugo-Caballero, Karla Dzul-Rosado, Georgina Rodríguez-Moreno, Raúl Tello-Martín, Karina López-Ávila, Jorge Zavala-Castro
Rocky Mountain spotted fever is a disease caused by Rickettsia rickettsii, a bacteria transmitted by infected ticks. It is characterized by fever, exanthema, arthralgias and myalgias; but sometimes its clinical presentation is non specific. Due to its similarities with other exanthematic diseases like dengue or chikungunya, Rocky Mountain spotted fever is not a first line diagnosis, even though countries like Mexico show the ecologic and socioeconomic characteristics that favor its transmission, with a 30% mortality rate among pediatric patients...
1, 2017: Archivos Argentinos de Pediatría
https://www.readbyqxmd.com/read/28095503/detection-of-a-potential-new-bartonella-species-candidatus-bartonella-rondoniensis-in-human-biting-kissing-bugs-reduviidae-triatominae
#16
Maureen Laroche, Jean-Michel Berenger, Oleg Mediannikov, Didier Raoult, Philippe Parola
BACKGROUND: Among the Reduviidae family, triatomines are giant blood-sucking bugs. They are well known in Central and South America where they transmit Trypanosoma cruzi to mammals, including humans, through their feces. This parasitic protozoan is the causative agent of Chagas disease, a major public health issue in endemic areas. Because of the medical and economic impact of Chagas disease, the presence of other arthropod-borne pathogens in triatomines was rarely investigated. METHODOLOGY/PRINCIPAL FINDINGS: In this study, seven triatomines species involved in the transmission of T...
January 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28089350/rickettsia-prowazekii-methionine-aminopeptidase-as-a-promising-target-for-the-development-of-antibacterial-agents
#17
Travis R Helgren, Congling Chen, Phumvadee Wangtrakuldee, Thomas E Edwards, Bart L Staker, Jan Abendroth, Banumathi Sankaran, Nicole A Housley, Peter J Myler, Jonathon P Audia, James R Horn, Timothy J Hagen
Methionine aminopeptidase (MetAP) is a class of ubiquitous enzymes essential for the survival of numerous bacterial species. These enzymes are responsible for the cleavage of N-terminal formyl-methionine initiators from nascent proteins to initiate post-translational modifications that are often essential to proper protein function. Thus, inhibition of MetAP activity has been implicated as a novel antibacterial target. We tested this idea in the present study by targeting the MetAP enzyme in the obligate intracellular pathogen Rickettsia prowazekii...
November 10, 2016: Bioorganic & Medicinal Chemistry
https://www.readbyqxmd.com/read/28077317/zoonotic-pathogens-in-atlantic-forest-wild-rodents-in-brazil-bartonella-and-coxiella-infections
#18
Tatiana Rozental, Michelle Santos Ferreira, Alexandro Guterres, Maria Angélica Mares-Guia, Bernardo R Teixeira, Jonathan Gonçalves, Cibele Rodrigues Bonvicino, Paulo Sergio D'Andrea, Elba Regina Sampaio de Lemos
Zoonotic pathogens comprise a significant and increasing fraction of all emerging and re-emerging infectious diseases that plague humans. Identifying host species is one of the keys to controlling emerging infectious diseases. From March 2007 until April 2012, we collected a total of 131 wild rodents in eight municipalities of Rio de Janeiro, Brazil. We investigated these rodents for infection with Coxiella burnetii, Bartonella spp. and Rickettsia spp. In total, 22.1% (29/131) of the rodents were infected by at least one pathogen; co-infection was detected in 1...
January 8, 2017: Acta Tropica
https://www.readbyqxmd.com/read/28073909/the-detection-of-spotted-fever-group-rickettsia-dna-in-tick-samples-from-pastoral-communities-in-kenya
#19
Hellen Koka, Rosemary Sang, Helen Lydia Kutima, Lillian Musila
In this study, ticks from pastoral communities in Kenya were tested for Rickettsia spp. infections in geographical regions where the presence of tick-borne arboviruses had previously been reported. Rickettsial and arbovirus infections have similar clinical features which makes differential diagnosis challenging when both diseases occur. The tick samples were tested for Rickettsia spp. by conventional PCR using three primer sets targeting the gltA, ompA, and ompB genes followed by amplicon sequencing. Of the tick pools screened, 25% (95/380) were positive for Rickettsia spp...
January 10, 2017: Journal of Medical Entomology
https://www.readbyqxmd.com/read/28072914/presence-of-pathogenic-rickettsiae-and-protozoan-in-samples-of-raw-milk-from-cows-goats-and-sheep
#20
Ewa Cisak, Violetta Zając, Jacek Sroka, Anna Sawczyn, Anna Kloc, Jacek Dutkiewicz, Angelina Wójcik-Fatla
OBJECTIVE: The aim of the present work was to determine the presence of various rickettsiae and protozoan in raw milk and the assessment the potential, milk-borne route in the spread of selected zoonotic pathogens. MATERIALS: A total of 119 raw milk samples collected randomly from 63 cows, 29 goats, and 27 sheep bred on 34 farms situated on eight communities in eastern Poland were examined by polymerase chain reaction (PCR) method for the presence of pathogenic rickettsiae (Coxiella burnetii, Anaplasma phagocytophilum, and Rickettsia spp...
January 10, 2017: Foodborne Pathogens and Disease
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