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https://www.readbyqxmd.com/read/29235734/comparison-of-the-long-term-oncological-outcomes-of-stent-as-a-bridge-to-surgery-and-surgery-alone-in-malignant-colonic-obstruction
#1
Udit Gibor, Zvi Perry, Dan Tirosh, Uri Netz, Alex Rosental, Alex Fich, Sofie Man, Samuel Ariad, Boris Kirshtein
BACKGROUND: Self-expanding metallic stents (SEMS) insertion is an alternative to emergency surgery in malignant colonic obstruction. However, the long-term oncological outcome of stents as a bridge to surgery is limited and controversial. OBJECTIVES: To determine the long-term oncological outcome of stents as a bridge to surgery. METHODS: Data of patients who underwent emergency surgery and endoscopic stent insertion as a bridge to surgery due to obstructing colon cancer at Soroka Medical Center during a 14 year period were collected retrospectively...
December 2017: Israel Medical Association Journal: IMAJ
https://www.readbyqxmd.com/read/29235197/superoxide-dismutase-from-helicobacter-pylori-suppresses-the-production-of-pro-inflammatory-cytokines-during-in-vivo-infection
#2
Andrew Stent, Alison L Every, Yok T Chionh, Garrett Z Ng, Philip Sutton
BACKGROUND: Helicobacter pylori has undergone considerable adaptation to allow chronic persistence within the gastric environment. While H. pylori-associated diseases are driven by an excessive inflammation, severe gastritis is detrimental to colonization by this pathogen. Hence, H. pylori has developed strategies to minimize the severity of gastritis it triggers in its host. Superoxide dismutase (SOD) is well known for its role in protecting against oxidative attack; less recognized is its ability to inhibit immunity, shown for SOD from mammalian sources and those of some bacterial species...
December 13, 2017: Helicobacter
https://www.readbyqxmd.com/read/29235008/oncological-assessment-of-stent-placement-for-obstructive-colorectal-cancer-from-circulating-cell-free-dna-and-circulating-tumor-dna-dynamics
#3
Goro Takahashi, Takeshi Yamada, Takuma Iwai, Kohki Takeda, Michihiro Koizumi, Seiichi Shinji, Eiji Uchida
BACKGROUND: The self-expanding metallic stent (SEMS) provides effective decompression for patients with malignant large bowel obstruction (MLBO); however, mechanical damage to malignant cells from insertion may negatively affect prognosis, similar to surgical manipulation, and its oncological safety is unclear. We examined mechanical damage from SEMS placement using circulating cell-free DNA (cfDNA) and circulating tumor DNA (ctDNA). METHODS: Between 1 November 2014 and 30 June 2017, 35 MLBO patients were analyzed, comprising 25 SEMS patients and 10 transanal decompression tube (TDT) patients (control)...
December 12, 2017: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/29230969/laparoscopic-colectomy-after-self-expanding-metallic-stent-placement-through-the-ileocecal-valve-for-right-sided-malignant-colonic-obstruction-a-case-report
#4
Hiroshi Takeyama, Katsuki Danno, Yuya Kogita, Takahiko Nishigaki, Masafumi Yamashita, Masami Yamazaki, Tsuyoshi Yamakita, Akihiro Nishihara, Minako Hoshi, Hirokazu Taniguchi, Masayo Mizutani, Itsuko Nakamichi, Mamoru Yura, Kimimasa Ikeda, Eiji Kurokawa
A 78-year-old man with a history of open sigmoidectomy for sigmoid cancer presented with abdominal pain and vomiting. Abdominal multi-detector CT revealed an obstructive ileocecal tumor with distended small bowel on the oral side. We performed emergency drainage using a transnasal decompression tube, and 2 days later, we conducted a colonoscopic examination, which lead to a provisional diagnosis of obstruction with a malignant tumor invading the ileocecal valve. We then placed a self-expanding metallic stent (SEMS) through the ileocecal valve...
December 12, 2017: Asian Journal of Endoscopic Surgery
https://www.readbyqxmd.com/read/29218593/-colonic-stent-as-bridge-to-surgery-versus-emergency-resection-in-patients-with-malignant-colonic-stenosis
#5
J Reibetanz, C T Germer
No abstract text is available yet for this article.
December 7, 2017: Der Chirurg; Zeitschrift Für Alle Gebiete der Operativen Medizen
https://www.readbyqxmd.com/read/29215476/clinical-outcomes-of-self-expandable-metal-stents-for-malignant-rectal-obstruction
#6
Hyun Jung Lee, Sung Pil Hong, Jae Hee Cheon, Tae Il Kim, Won Ho Kim, Soo Jung Park
BACKGROUND: Self-expandable metal stents are widely used to treat malignant colorectal obstruction. However, data on clinical outcomes of stent placement for rectal obstruction specifically are lacking. OBJECTIVE: We aimed to investigate the clinical outcomes of self-expandable metal stents in malignant rectal obstruction in comparison with those in left colonic obstruction and to identify factors associated with clinical failure and complication. DESIGN: This was a retrospective study...
January 2018: Diseases of the Colon and Rectum
https://www.readbyqxmd.com/read/29212105/-german-society-of-gastroenterology-digestive-and-metabolic-diseases-dgvs-position-statement-on-endoscopic-decompression-in-acute-ileus
#7
Martin Götz, Georg Braun, Ralf Jakobs, Helmut Messmann, Eduard F Stange, Markus M Lerch
In patients with ileus with dilated intestine in imaging studies, endoscopic decompression appears a feasible option. However, its use is often uncritical and without scientific evidence. Before considering endoscopic intervention, CT-imaging should differentiate between mechanical obstruction and paralytic ileus/intestinal pseudo-obstruction. Tumor diagnosis and localisation are essential because the latter determines the choice of the decompression procedure. Coecal dilatation of more than 12 cm indicates an increased risk of perforation...
December 2017: Zeitschrift Für Gastroenterologie
https://www.readbyqxmd.com/read/29205045/colon-ascendens-stent-peritonitis-casp-induces-excessive-inflammation-and-systemic-metabolic-dysfunction-in-a-septic-rat-model
#8
Limin Zhang, Yuan Tian, Jianfen Yang, Jieshou Li, Huiru Tang, Yulan Wang
The colon ascendens stent peritonitis (CASP) surgery creates a leakage of intestinal contents, resulting in polymicrobial sepsis associated with a high risk for postoperative multiple organ failure and death in surgical patients. To evaluate the effects of CASP on multiple organs, we analyzed the systemic metabolic consequences in liver, kidney, lung and heart of rats after CASP by employing a combination of metabolomics, clinical chemistry and biological assays. We found that CASP surgery after 18 h caused significant elevations of lipid, amino acids, acetate, choline, PC and GPC in rat liver together with significant depletion of glucose and glycogen...
December 5, 2017: Journal of Proteome Research
https://www.readbyqxmd.com/read/29197194/the-role-of-self-expandable-metallic-stents-as-bridge-to-surgery-for-the-treatment-of-acute-malignant-colorectal-obstruction-our-experience
#9
Gianpasquale Gallo, Giuseppe Sammarco, Alessandro Paolo Chiriatti, Ferdinando Calabria, Rosario Sacco
INTRODUCTION: Despite the widespread use of screening programs, the colorectal cancer occurs in 7-29% of cases with a bowel obstruction, needing an immediate decompression treatment by emergency surgery; unfortunately, the emergency surgery is characterized by high morbidity and mortality rates. The endoscopic placement of self-expandable metallic stents can be a useful alternative, allowing to decompress the acute obstruction in a short time, in order to correct dehydration, electrolytic imbalance and to improve the overall clinical conditions prior to adequately plan the intervention of elective surgery...
2017: Annali Italiani di Chirurgia
https://www.readbyqxmd.com/read/29186091/-managerial-and-methodological-aspects-of-emergency-surgery-for-malignant-colonic-obstruction
#10
A V Shabunin, Z A Bagateliya, D D Dolidze, A V Vardanyan
AIM: To determine the most feasible treatment strategy for malignant colonic obstruction. MATERIAL AND METHODS: There were 427 patients with malignant colonic obstruction who were hospitalized for emergency indications. 30 of them were treated with medical therapy; 286 - underwent acute resection; 43 - stoma construction; 68 - stents deployment. 64 out of 427 patients underwent elective restorative/radical surgery and radio- or chemotherapy in 1-8 months. 3-year Kaplan-Meier survival was assessed...
2017: Khirurgiia
https://www.readbyqxmd.com/read/29184691/long-term-oncologic-outcomes-of-stent-as-a-bridge-to-surgery-versus-emergency-surgery-in-malignant-left-side-colonic-obstructions-a-meta-analysis
#11
Marco Ceresoli, Niccolò Allievi, Federico Coccolini, Giulia Montori, Paola Fugazzola, Michele Pisano, Massimo Sartelli, Fausto Catena, Luca Ansaloni
Background: The placement of a metallic stent as a bridge to surgery (SBTS) could represents an option for the treatment of left-sided malignant colonic obstruction in centres with adequate skills. Several meta-analyses demonstrated better short-term outcomes after SBTS when compared with emergency surgery (ES); however, some studies reported a higher local recurrence rate. The aim of the present review is to investigate the long-term outcomes of stent bridge to surgery as compared to ES...
October 2017: Journal of Gastrointestinal Oncology
https://www.readbyqxmd.com/read/29176403/tlr4-and-nlrp3-caspase-1-il-1%C3%AE-axis-are-not-involved-in-colon-ascendens-stent-peritonitis-casp-associated-heart-disease
#12
Maria Micaela Lopez Alarcón, Julieta Fernández Ruocco, Fabiano Ferreira, Heitor A Paula-Neto, Marisa Sepúlveda, Martín Vila Petroff, Adriana Bastos Carvalho, Isalira Peroba Ramos, Hugo Justino Branda, Claudia Neto Paiva, Emiliano Medei
Hemodynamic collapse and myocardial dysfunction are among the major causes of death in severe sepsis. The purpose of this study was to assess the role played by TLR4 and by the NLRP3 inflammasome in the cardiac dysfunction that occurs after high-grade polymicrobial sepsis. We performed the colon ascendens stent peritonitis (CASP) surgery in Tlr4, Nlrp3 and caspase-1 mice. We also assessed for the first time the electrical heart function in the CASP model. The QJ interval was increased in wild-type C57BL/6J mice after CASP when compared to sham controls, a result paralleled by an increase in the cardiac action potential duration (APD)...
November 15, 2017: Shock
https://www.readbyqxmd.com/read/29176370/percutaneous-transhepatic-y-shaped-stent-placement-in-portal-superior-mesenteric-vein-tumor-thrombosis-before-right-colectomy
#13
Antonio Pesce, Andrea Boncoraglio, Antonio Basile, Stefano Puleo
Portal-mesenteric tumor thrombosis represents a rare finding in patients with colorectal cancers. To our knowledge this is the first report of a patient diagnosed as having a wide stenosing right colon cancer with portal-superior mesenteric vein tumor thrombosis at the time of diagnosis, who was treated before surgery by positioning a percutaneous transhepatic Y-shaped stent through the main portal vein and the superior mesenteric vein. Percutaneous interventional procedures have gained worldwide acceptance for improving the symptoms of portal hypertension, because of their minimal invasiveness and high success rates with low number of complications...
November 15, 2017: Surgical Laparoscopy, Endoscopy & Percutaneous Techniques
https://www.readbyqxmd.com/read/29149965/comparision-of-ureteral-stent-colonization-between-deceased-and-live-donor-renal-transplant-recipients
#14
M Sarier, D Seyman, S Tekin, I Duman, B Uygun, M Demir, E Kukul, A H Yavuz
BACKGROUND: The use of a ureteral stent can cause a urinary tract infection (UTI), although it reduces urologic complications. UTIs are associated with a higher rate of ureteral stent colonization (USC). The aim of this study was to compare USC in living and deceased donor renal transplant recipients. MATERIAL AND METHODS: We conducted a prospective study of 48 patients who underwent renal transplantation between January and December 2016. The stents were removed aseptically, the inner surface of proximal and distal ends of stents were irrigated with liquid culture medium, and then they were vortexed for bacteriological investigation...
November 2017: Transplantation Proceedings
https://www.readbyqxmd.com/read/29126971/prevalence-and-postdischarge-incidence-of-malignancies-in-patients-with-acute-coronary-syndrome
#15
Alberto Cordero, Ramón López-Palop, Pilar Carrillo, Julio Núñez, Araceli Frutos, Vicente Bertomeu-González, Fernando Yépez, Nina Alcantara, Francisco Ribes, Mària Juskova, Vicente Bertomeu-Martínez
INTRODUCTION AND OBJECTIVES: Malignancies are the second cause of death in developed countries after cardiovascular disease and both share common risk factors. METHODS: This prospective study assessed the prevalence and postdischarge incidence of malignancies in all consecutive patients admitted for an acute coronary syndrome. RESULTS: A total of 1819 patients were included. On admission, the prevalence of malignancies was 3.4%, and 41.9% of the patients were considered disease-free; of the 1731 discharged patients, the incidence was 3...
November 7, 2017: Revista Española de Cardiología
https://www.readbyqxmd.com/read/29091349/randomised-controlled-trial-of-colonic-stent-insertion-in-non-curable-large-bowel-obstruction-a-post-hoc-cost-analysis
#16
Christopher J Young, Assad Zahid
AIM: With the increasing burden on the health care system, this study aims to perform a cost-effectiveness analysis on the management of incurable large bowel obstruction comparing the cost of a stent versus surgery. METHOD: A prospective randomised controlled trial was conducted at two major teaching hospitals in Australia between September 2006 and November 2011. 56 patients with malignant incurable large bowel obstruction were randomised to stent insertion or surgical decompression, of whom 52 were included in the final analysis...
November 1, 2017: Colorectal Disease: the Official Journal of the Association of Coloproctology of Great Britain and Ireland
https://www.readbyqxmd.com/read/29045026/feasibility-of-laparoscopic-surgery-after-stent-insertion-for-obstructive-colorectal-cancer
#17
Hideharu Shimizu, Ryoto Yamazaki, Hideo Ohtsuka, Itaru Osaka, Kunio Takuma, Yasuhiro Morita
INTRODUCTION: A growing number of patients with obstructive colorectal cancer are being treated with self-expanding metallic stents (SEMS) followed by laparoscopic resection. The aim of this study was to assess the feasibility of stent insertion and laparoscopic surgery for obstructive colorectal cancer and to compare these outcomes to regular laparoscopic surgery for non-obstructive colorectal cancer. METHODS: We retrospectively analyzed the outcomes of patients with a malignant colonic obstruction who underwent SEMS placement followed by elective laparoscopic resection...
October 17, 2017: Asian Journal of Endoscopic Surgery
https://www.readbyqxmd.com/read/29041018/can-a-modified-esophageal-stent-be-useful-in-the-treatment-of-nonresponsive-benign-colonic-anastomotic-stenosis
#18
Benedetto Mangiavillano, Mario Bianchetti, Alessandro Repici
No abstract text is available yet for this article.
October 17, 2017: Endoscopy
https://www.readbyqxmd.com/read/29033426/fracture-of-a-colonic-self-expandable-metallic-stent-in-malignant-colonic-obstruction-a-case-report
#19
Akinari Takao, Taku Tabata, Koichi Koizumi, Go Kuwata, Satomi Shibata, Makiko Mori, Kazuro Chiba, Sawako Kuruma, Tomoko Onishi, Takashi Fujiwara, Terumi Kamisawa, Junko Fujiwara, Takeo Arakawa, Kumiko Momma, Tatsu Shimoyama, Keiichi Takahashi
Self-expandable metallic stents (SEMSs) are used for the management of malignant colorectal obstruction. A patient who underwent colonic uncovered SEMS insertion for extraluminal stenosis in the splenic flexure of the transverse colon due to advanced gastric cancer is herein reported. The patient presented with a fracture of the colonic SEMS 494 days after SEMS insertion. Although various complications of stenting have previously been reported, the details of fractures of colonic SEMSs have not yet been reported...
October 16, 2017: Internal Medicine
https://www.readbyqxmd.com/read/29030789/foreign-bodies-in-sigmoid-colon-diverticulosis
#20
REVIEW
Ellen Ross, Patricia McKenna, John H Anderson
This review addresses the management of sigmoid colon diverticular disease associated with foreign bodies. In addition, two novel cases are presented. One case describes the management of diverticular bleeding secondary to a chicken bone and the other case reports retrieval of a retained EndoRings™ Device. The review identified 40 relevant publications including 50 subjects. Foreign bodies within sigmoid diverticular disease may be associated with inflammation, perforation, abscess and fistula. In current practice, diagnosis is often achieved with CT scan...
December 2017: Clinical Journal of Gastroenterology
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