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intentional cardiology

Patrick Y Jay, Ehiole Akhirome, Rachel A Magnan, M Rebecca Zhang, Lillian Kang, Yidan Qin, Nelson Ugwu, Suk Dev Regmi, Julie M Nogee, James M Cheverud
Despite decades of progress, congenital heart disease remains a major cause of mortality and suffering in children and young adults. Prevention would be ideal, but formidable biological and technical hurdles face any intervention that seeks to target the main causes, genetic mutations in the embryo. Other factors, however, significantly modify the total risk in individuals who carry mutations. Investigation of these factors could lead to an alternative approach to prevention. To define the risk modifiers, our group has taken an "experimental epidemiologic" approach via inbred mouse strain crosses...
November 5, 2016: Molecular and Cellular Endocrinology
Natália Fracaro Lombardi, Antonio Eduardo Matoso Mendes, Rosa Camila Lucchetta, Wálleri Christini Torelli Reis, Maria Luiza Drechsel Fávero, Cassyano Januário Correr
OBJECTIVES: this observational study aimed to describe the discrepancies identified during medication reconciliation on patient admission to cardiology units in a large hospital. METHODS: the medication history of patients was collected within 48 hours after admission, and intentional and unintentional discrepancies were classified as omission, duplication, dose, frequency, timing, and route of drug administration. RESULTS: most of the patients evaluated were women (58...
2016: Revista Latino-americana de Enfermagem
Luis Fernando Ng-Sueng, Iván Vargas-Matos, Percy Mayta-Tristán, Reneé Pereyra-Elías, Juan José Montenegro-Idrogo, Fiorella Inga-Berrospi, Felix Ancalli, Francisco Bonilla-Escobar, Cristian Diaz-Velez, Erick Gutierrez-Quezada, Jennifer Gomez-Alhach, Carlos E Muñoz-Medina, Adriana Sanchez-Pozo, Milisen Vidal
INTRODUCTION: The selection of a medical specialty has been associated with multiple factors, such as personal preferences, academic exposure, motivational factors and sociodemographic factors, such as gender. The number of women in the medical field has increased in recent years. In Latin America, we have not found any studies that explore this relationship. OBJECTIVE: To determine whether there is an association between gender and the intention to choose a medical specialty in medical students from 11 countries in Latin America...
2016: PloS One
Saar Danon, Robert G Gray, Matthew A Crystal, Gareth Morgan, Daniel H Gruenstein, Bryan H Goldstein, Brent M Gordon
OBJECTIVE: Intravascular stents are now routinely used to treat young patients with vascular stenoses. Future stent redilations are often necessary to account for somatic growth. The purpose of this study was to compile a database of characteristics for stents commonly used in the treatment of congenital heart disease patients, and compare serial dilation to direct dilation to the maximal diameter. DESIGN: A standardized bench testing protocol was established and utilized in the assessment of all stents...
July 27, 2016: Congenital Heart Disease
Tanja Dekkers, Aleksander Prejbisz, Leo J Schultze Kool, Hans J M M Groenewoud, Marieke Velema, Wilko Spiering, Sylwia Kołodziejczyk-Kruk, Mark Arntz, Jacek Kądziela, Johannes F Langenhuijsen, Michiel N Kerstens, Anton H van den Meiracker, Bert-Jan van den Born, Fred C G J Sweep, Ad R M M Hermus, Andrzej Januszewicz, Alike F Ligthart-Naber, Peter Makai, Gert-Jan van der Wilt, Jacques W M Lenders, Jaap Deinum
BACKGROUND: The distinction between unilateral aldosterone-producing adenoma or bilateral adrenal hyperplasia as causes of primary aldosteronism is usually made by adrenal CT or by adrenal vein sampling (AVS). Whether CT or AVS represents the best test for diagnosis remains unknown. We aimed to compare the outcome of CT-based management with AVS-based management for patients with primary aldosteronism. METHODS: In a randomised controlled trial, we randomly assigned patients with aldosteronism to undergo either adrenal CT or AVS to determine the presence of aldosterone-producing adenoma (with subsequent treatment consisting of adrenalectomy) or bilateral adrenal hyperplasia (subsequent treatment with mineralocorticoid receptor antagonists)...
September 2016: Lancet Diabetes & Endocrinology
Maria G Crespo-Leiro, Stefan D Anker, Aldo P Maggioni, Andrew J Coats, Gerasimos Filippatos, Frank Ruschitzka, Roberto Ferrari, Massimo Francesco Piepoli, Juan F Delgado Jimenez, Marco Metra, Candida Fonseca, Jaromir Hradec, Offer Amir, Damien Logeart, Ulf Dahlström, Bela Merkely, Jaroslaw Drozdz, Eva Goncalvesova, Mahmoud Hassanein, Ovidiu Chioncel, Mitja Lainscak, Petar M Seferovic, Dimitris Tousoulis, Ausra Kavoliuniene, Friedrich Fruhwald, Emir Fazlibegovic, Ahmet Temizhan, Plamen Gatzov, Andrejs Erglis, Cécile Laroche, Alexandre Mebazaa
AIMS: The European Society of Cardiology Heart Failure Long-Term Registry (ESC-HF-LT-R) was set up with the aim of describing the clinical epidemiology and the 1-year outcomes of patients with heart failure (HF) with the added intention of comparing differences between participating countries. METHODS AND RESULTS: The ESC-HF-LT-R is a prospective, observational registry contributed to by 211 cardiology centres in 21 European and/or Mediterranean countries, all being member countries of the ESC...
June 2016: European Journal of Heart Failure
Ricardo C Cury, Suhny Abbara, Stephan Achenbach, Arthur Agatston, Daniel S Berman, Matthew J Budoff, Karin E Dill, Jill E Jacobs, Christopher D Maroules, Geoffrey D Rubin, Frank J Rybicki, U Joseph Schoepf, Leslee J Shaw, Arthur E Stillman, Charles S White, Pamela K Woodard, Jonathon A Leipsic
The intent of CAD-RADS - Coronary Artery Disease Reporting and Data System is to create a standardized method to communicate findings of coronary CT angiography (coronary CTA) in order to facilitate decision-making regarding further patient management. The suggested CAD-RADS classification is applied on a per-patient basis and represents the highest-grade coronary artery lesion documented by coronary CTA. It ranges from CAD-RADS 0 (Zero) for the complete absence of stenosis and plaque to CAD-RADS 5 for the presence of at least one totally occluded coronary artery and should always be interpreted in conjunction with the impression found in the report...
July 2016: Journal of Cardiovascular Computed Tomography
Ricardo C Cury, Suhny Abbara, Stephan Achenbach, Arthur Agatston, Daniel Berman, Matthew Budoff, Karin Dill, Jill Jacobs, Christopher Maroules, Geoffrey Rubin, Frank J Rybicki, Joseph Schoepf, Leslee Shaw, Arthur Stillman, Charles White, Pamela Woodard, Jonathon Leipsic
The intent of CAD-RADS - Coronary Artery Disease Reporting and Data System is to create a standardized method to communicate findings of coronary CT angiography (coronary CTA) in order to facilitate decision-making regarding further patient management. The suggested CAD-RADS classification is applied on a per-patient basis and represents the highest-grade coronary artery lesion documented by coronary CTA. It ranges from CAD-RADS 0 (Zero) for the complete absence of stenosis and plaque to CAD-RADS 5 for the presence of at least one totally occluded coronary artery and should always be interpreted in conjunction with the impression found in the report...
June 14, 2016: Journal of the American College of Radiology: JACR
Husam Abdel-Qadir, Eitan Amir, Paaladinesh Thavendiranathan
Cancer treatment-related cardiac dysfunction (CTRCD) occurs with many agents used in the treatment of cancer. This is most relevant in patients receiving cancer treatment with curative intent as opposed to those treated with a palliative intent where lifespan is more likely to be limited by the cancer diagnosis. Clinicians need to be aware of methods to prevent, detect, and manage CTRCD. This article frames an approach to CTCRD based on the American College of Cardiology/American Heart Association stages of heart failure (HF)...
July 2016: Canadian Journal of Cardiology
Marlon I Spreen, Jasper M Martens, Bettina E Hansen, Bob Knippenberg, Elke Verhey, Lukas C van Dijk, Jean-Paul P M de Vries, Jan-Albert Vos, Gert Jan de Borst, Evert-Jan P A Vonken, Jan J Wever, Randolph G Statius van Eps, Willem P Th M Mali, Hans van Overhagen
BACKGROUND: Endovascular infrapopliteal treatment of patients with critical limb ischemia using percutaneous transluminal angioplasty (PTA) and bail-out bare metal stenting (BMS) is hampered by restenosis. In interventional cardiology, drug-eluting stents (DES) have shown better patency rates and are standard practice nowadays. An investigator-initiated, multicenter, randomized trial was conducted to assess whether DES also improve patency and clinical outcome of infrapopliteal lesions...
February 2016: Circulation. Cardiovascular Interventions
Jean Fajadet, Shelley Wood, William Wijns
Live-case demonstrations have become essential teaching tools. Debate about their added educational value and risk-benefit considerations vis-à-vis patient safety demand that major interventional cardiology meetings offering live-case demonstrations carefully define and monitor the objectives and quality of the cases included at their meetings. To this end, Europa Organisation, the content-providing group that supports EuroPCR and other PCR conferences internationally, has convened the PCR VITAL-Live Workshop, bringing together senior interventional cardiologists and experienced live-case operators with the aim of defining and reviewing the key components and goals of valuable live-case demonstrations...
December 18, 2015: European Heart Journal
Wiebke Kempin, Sebastian Kaule, Thomas Reske, Niels Grabow, Svea Petersen, Stefan Nagel, Klaus-Peter Schmitz, Werner Weitschies, Anne Seidlitz
Lately, drug-coated balloons have been introduced in interventional cardiology as an approach to treat occluded blood vessel. They were developed for the rapid transfer of antiproliferative drugs during the angioplasty procedure in stenosed vessels with the intent to reduce the risk of restenosis. In this study five different paclitaxel (PTX) balloon coatings were tested in vitro in order to examine how solvents and additives influence coating stability and drug transfer rates. PTX-coated balloons were advanced through a guiding catheter and a simulated coronary artery pathway under perfusion and were then inflated in a hydrogel acceptor compartment...
October 2015: European Journal of Pharmaceutics and Biopharmaceutics
Laure Lavaill, Alain Dussaucy, Karine Bardonnet, Nicolas Duraffourg, Elisabeth Monnet, Thierry Thévenot, Siamak Davani, Vincent Di Martino
BACKGROUND/AIM: We evaluated the relevance of a systematic automatic detection of cirrhosis using biochemical markers in hospitalized patients. METHODS: We automatically calculated three free biochemical tests (APRI, Fib-4, and Forns) in patients consecutively hospitalized in our university hospital between July and September, 2010. Patients >18 years not known to suffer from chronic liver disease, were contacted to undergo liver stiffness measurement (LSM) as a reference diagnostic tool...
January 2016: European Journal of Gastroenterology & Hepatology
Michèle Baumann, Anastase Tchicaya, Kyle Vanderpool, Nathalie Lorentz, Etienne Le Bihan
BACKGROUND: Five years after coronary angiography, life satisfaction (LS) among patients may be related to incidents of cardiovascular diseases, risk factors and unhealthy behaviours and socioeconomic conditions, but their respective influence remains unclear. Our aim is to analyze LS and its relationships with those factors. METHODS: Among the 4,391 patients initially contacted, 547 deaths were reported and 209 had an invalid address. In 2013-2014, 3,635 patients who underwent coronary angiography in 2008-2009 at the National Institute of Cardiac Surgery and Cardiological Intervention (INCCI) in Luxembourg were asked to complete a self-administered questionnaire assessing LS [1-10] and other variables...
2015: BMC Public Health
Chete M Eze-Nliam, Zugui Zhang, Sandra A Weiss, William S Weintraub
Health care is a vital good for which there is an infinite demand. However, societal resources are finite and need to be distributed efficiently to avoid waste. Thus, the relative value of an intervention - cost compared to its effectiveness- needs to be taken into consideration when deciding which interventions to adopt. Cost-effectiveness analysis provides the crucial information which guides these decisions. As the field of medicine and indeed cardiology move forward with innovations which are effective but often expensive, it becomes imperative to employ these cost-effectiveness analytic tools, not with the intention of denying vital health services but to ascertain what the society willing to pay for...
2014: Interventional Cardiology
Simon Stewart, Yih-Kai Chan, Chiew Wong, Garry Jennings, Paul Scuffham, Adrian Esterman, Melinda Carrington
AIMS: The aim of this study was to determine the effectiveness of a long-term, nurse-led, multidisciplinary programme of home/clinic visits in preventing progressive cardiac dysfunction in individuals at risk of developing de novo chronic heart failure (CHF). METHODS AND RESULTS: A pragmatic, single-centre (tertiary-referral hospital with specialist cardiological services), open-label, randomized controlled trial with blinded endpoint adjudication was carried out...
June 2015: European Journal of Heart Failure
(no author information available yet)
BACKGROUND: The benefit of CT coronary angiography (CTCA) in patients presenting with stable chest pain has not been systematically studied. We aimed to assess the effect of CTCA on the diagnosis, management, and outcome of patients referred to the cardiology clinic with suspected angina due to coronary heart disease. METHODS: In this prospective open-label, parallel-group, multicentre trial, we recruited patients aged 18-75 years referred for the assessment of suspected angina due to coronary heart disease from 12 cardiology chest pain clinics across Scotland...
June 13, 2015: Lancet
K-H Kuck, T Tönnis
The latest guidelines of the European Society of Cardiology (ESC) on cardiac pacing and cardiac resynchronization therapy were presented and published in June 2013. Compared to the last guidelines from 2007 several substantial changes have been made. The new guidelines are much more clinically oriented with a special focus on practicability. The intention is a better usefulness not only for electrophysiologists but also for cardiologists, internists and general practitioners.
December 2014: Herz
Sherrie Khadanga, Clara V Massey
BACKGROUND: Vitamin D insufficiency is increasingly gaining prominence as an associated cardiovascular disease (CVD) risk factor, often thought to be an issue in colder climates and higher altitudes. The intent of this study was to ascertain vitamin D levels in the southern Alabama gulf-coast region that has a high number of sunny days along with an annual average elevated UV ray index. METHODS: An observational retrospective study of 204 patients with established CVD treated at the University of South Alabama's Heart Center from January 2007 through January 2013 was undertaken...
December 2014: Journal of Clinical Medicine Research
Jennifer A Tremmel, Rajan A G Patel, Deepak L Bhatt, Mehmet Cilingiroglu, Duane S Pinto, Larry S Dean, Cindy L Grines
With the plethora of clinical trials, it is difficult for busy interventional cardiologists to stay up to date. Therefore, the SCAI publications committee concisely summarizes and provides editorial commentary on the most important trials from recent, large international meetings. The intent is to provide this summary every six months to allow quick assimilation of trial results into interventional practice. © 2014 Wiley Periodicals, Inc.
January 1, 2015: Catheterization and Cardiovascular Interventions
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