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Hand osteoarthritis

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https://www.readbyqxmd.com/read/28544753/no-association-between-metabolic-syndrome-and-radiographic-hand-osteoarthritis-data-from-the-framingham-study
#1
Mette P Strand, Tuhina Neogi, Jingbo Niu, David T Felson, Ida K Haugen
OBJECTIVE: To explore whether metabolic syndrome (MetS) and its components are associated with hand OA using longitudinal data from the Framingham study. METHODS: In our cross-sectional analyses we included 1089 persons (age 50-75 years), of whom 785 had 7-year longitudinal radiographs. Of these, 586 with no hand OA at baseline were included in analyses on hand OA incidence. We explored associations between and MetS and its components (central obesity, hypertension, diabetes, triglyceridemia, low high-density lipoprotein) and radiographic hand OA (defined as ≥2 interphalangeal joints with Kellgren-Lawrence grade≥2) using logistic regression analyses with adjustment for age, sex and body mass index (BMI)...
May 23, 2017: Arthritis Care & Research
https://www.readbyqxmd.com/read/28542024/omega-6-omega-3-pufa-ratio-pain-functioning-and-distress-in-adults-with-knee-pain
#2
Kimberly T Sibille, Christopher King, Timothy J Garrett, Toni L Glover, Hang Zhang, Huaihou Chen, Divya Reddy, Burel R Goodin, Adriana Sotolongo, Megan E Petrov, Yenisel Cruz-Almeida, Matthew Herbert, Emily J Bartley, Jeffrey C Edberg, Roland Staud, David T Redden, Laurence A Bradley, Roger B Fillingim
OBJECTIVES: Osteoarthritis (OA) is associated with inflammation, chronic pain, functional limitations, and psychosocial distress. High Omega-3 (n-3) polyunsaturated fatty acids (PUFAs) are associated with lower levels of inflammatory mediators, anti-nociception, and adaptive cognitive/emotional functioning. High Omega-6 (n-6) PUFAs are associated with inflammation, nociception, and psychological distress. While findings related to n-3 supplementation in knee OA are mixed, consideration of the n-6:n-3 ratio and additional outcome measures may provide improved understanding of the potential relevance of these fatty acids in OA...
May 24, 2017: Clinical Journal of Pain
https://www.readbyqxmd.com/read/28536825/intramuscular-clodronate-in-erosive-osteoarthritis-of-the-hand-is-effective-on-pain-and-reduces-serum-comp-a-randomized-pilot-trial-the-er-o-d-e-study-erosive-osteoarthritis-and-disodium-clodronate-evaluation
#3
Gianantonio Saviola, Lul Abdi-Ali, Maria Rosaria Povino, Lorella Campostrini, Silvano Sacco, Luca Dalle Carbonare
We evaluated the efficacy and safety of intramuscular clodronate (CLO) for the treatment of active erosive osteoarthritis of the hand (EOA). Forty outpatients treated with anti-inflammatory (NSAIDs) or analgesic drugs since at least 6 months, for at least 3 days a week, were randomly divided into two groups. Group A: 24 patients treated for 6 months with intramuscular (i.m.) CLO added to usual NSAIDs or analgesic drugs. The attack dose was 200 mg/day i.m. for 10 days followed by a maintenance dose of CLO i...
May 23, 2017: Clinical Rheumatology
https://www.readbyqxmd.com/read/28535729/quantitative-genetics-of-circulating-hyaluronic-acid-ha-and-its-correlation-with-hand-osteoarthritis-and-obesity-related-phenotypes-in-a-community-based-sample
#4
Jai Prakash, Gulzhan Gabdulina, Svetlana Trofimov, Gregory Livshits
BACKGROUND: One of the potential molecular biomarkers of osteoarthritis (OA) is hyaluronic acid (HA). HA levels may be related to the severity and progression of OA. However, little is known about the contribution of major risk factors for osteoarthritis, e.g., obesity-related phenotypes and genetics to HA variation. AIM: To clarify the quantitative effect of these factors on HA. METHODS: An ethnically homogeneous sample of 911 apparently healthy European-derived individuals, assessed for radiographic hand osteoarthritis (RHOA), HA, leptin, adiponectin, and several anthropometrical measures of obesity-related phenotypes...
May 24, 2017: Annals of Human Biology
https://www.readbyqxmd.com/read/28529663/the-modified-dunn-procedure-for-slipped-capital-femoral-epiphysis-the-bernese-experience
#5
M Tannast, L M Jost, T D Lerch, F Schmaranzer, K Ziebarth, K A Siebenrock
PURPOSE: Based on previous investigations on the vascular blood supply to the femoral head, a technique for anatomical reduction after slipped capital femoral epiphysis was developed. This technique is a modification of the original technique by Dunn using a retinacular soft-tissue flap. This allows the visual control of the epiphyseal vascular blood supply. We report the experience at the inventor's institution with a critical discussion of the available literature. METHODS: Using a trochanteric osteotomy for surgical dislocation of the hip, a retinacular soft tissue flap is created containing the deep branch of the medial femoral circumflex artery, the external rotators and the capsule...
April 2017: Journal of Children's Orthopaedics
https://www.readbyqxmd.com/read/28525958/necessity-of-immobilizing-the-metacarpophalangeal-joint-in-carpometacarpal-osteoarthritis-short-term-effect
#6
Raquel Cantero-Téllez, Kristin Valdes, Deborah A Schwartz, Ivan Medina-Porqueres, Jean Christophe Arias, Jorge H Villafañe
BACKGROUND: Conservative treatment for carpometacarpal (CMC) joint osteoarthritis (OA) may include orthotic fabrication to decrease pain. Different types of orthoses have been used as conservative interventions to improve symptoms, but there are no guidelines specifying if inclusion of the thumb metacarpophalangeal (MCP) in an orthosis is required in the treatment of thumb CMC joint OA. The main objective of this study is to determine the effectiveness of 2 different thumb CMC joint orthotic designs on pain reduction and improved hand function: one design immobilizes both the MCP joint and the CMC joint and the other design immobilizes only the CMC joint...
May 1, 2017: Hand: Official Journal of the American Association for Hand Surgery
https://www.readbyqxmd.com/read/28512850/in-situ-handheld-3d-bioprinting-for-cartilage-regeneration
#7
Claudia Di Bella, Serena Duchi, Cathal D O'Connell, Romane Blanchard, Cheryl Augustine, Zhilian Yue, Fletcher Thompson, Christopher Richards, Stephen Beirne, Carmine Onofrillo, Sebastien H Bauquier, Stewart D Ryan, Peter Pivonka, Gordon G Wallace, Peter F Choong
Articular cartilage injuries experienced at an early age can lead to the development of osteoarthritis later in life. In situ 3D printing is an exciting and innovative bio-fabrication technology that enables the surgeon to deliver tissue- engineering techniques at the time and location of need. We have created a hand- held 3D printing device (Biopen) that allows the simultaneous co-axial extrusion of bioscaffold and cultured cells directly into the cartilage defect in vivo in a single session surgery. This pilot study assesses the ability of the Biopen to repair a full thickness chondral defect and the early outcomes in cartilage regeneration, and compares these results to other treatments in a large animal model...
May 17, 2017: Journal of Tissue Engineering and Regenerative Medicine
https://www.readbyqxmd.com/read/28512004/contribution-of-high-resolution-peripheral-quantitative-ct-to-the-management-of-bone-and-joint-diseases
#8
Eric Lespessailles, Nada Ibrahim-Nasser, Hechmi Toumi, Roland Chapurlat
Many imaging modalities have been described to diagnose and monitor osteoporosis (OP), osteoarthritis and inflammatory rheumatic diseases. Over the last ten years, High Resolution peripheral Quantitative Computerized Tomography (HR-pQCT) was shown to be a precise and non invasive technique to study bone and joint diseases in clinical research. It allows the study of both cortical and trabecular bone microarchitecture at the distal tibia and radius, and further applications have been developed such as the study of mechanical properties by the finite element analysis...
May 13, 2017: Joint, Bone, Spine: Revue du Rhumatisme
https://www.readbyqxmd.com/read/28511690/development-of-a-clinical-prediction-algorithm-for-knee-osteoarthritis-structural-progression-in-a-cohort-study-value-of-adding-measurement-of-subchondral-bone-density
#9
Michael P LaValley, Grace H Lo, Lori Lyn Price, Jeffrey B Driban, Charles B Eaton, Timothy E McAlindon
BACKGROUND: Risk prediction algorithms increase understanding of which patients are at greatest risk of a harmful outcome. Our goal was to create a clinically useful prediction algorithm for structural progression of knee osteoarthritis (OA), using medial joint space loss as a proxy; and to quantify the benefit of including periarticular bone mineral density (BMD) in the algorithm. METHODS: Participants were from the Osteoarthritis Initiative (OAI) Progression Cohort, with X-ray readings of medial joint space at 36- and 48-month visits, and a 30- or 36-month medial-to-lateral tibial BMD ratio (M:L BMD ratio) value...
May 16, 2017: Arthritis Research & Therapy
https://www.readbyqxmd.com/read/28510594/long-term-type-1-diabetes-is-associated-with-hand-pain-disability-and-stiffness-but-not-with-structural-hand-osteoarthritis-features-the-dialong-hand-study
#10
Karin Magnusson, Kristine Bech Holte, Niels Gunnar Juel, Jens Ivar Brox, Kåre Birger Hagen, Ida Kristin Haugen, Tore Julsrud Berg
OBJECTIVE: To explore whether having long-term type 1 diabetes (>45 years) is associated with a higher prevalence of radiographic hand OA, erosive hand OA and increased hand pain, disability and stiffness. METHODS: In total N = 96 persons with type 1 diabetes diagnosed before 1970 were included (mean [SD] age: 62.2 [7.4], mean [SD] HbA1c: 7.43 [0.80] and N = 49 [51%] men). Regular measurements of their HbA1c were obtained till 2015. We included N = 69 healthy controls without any diabetes (mean [SD] age: 63...
2017: PloS One
https://www.readbyqxmd.com/read/28506174/x-ray-guided-steroid-injections-for-proximal-interphalangeal-joint-osteoarthritis-of-the-fingers
#11
Clare A Miller, Stephen Dalgleish, Quentin Cox
BACKGROUND: Osteoarthritis of the finger proximal interphalangeal joints (PIPJ's) is common and severely limits hand function. Intra-articular steroid injections are frequently used, but there is little research assessing this treatment option. METHODS: This was a prospective audit of patients undergoing intra-articular steroid injections into the PIPJ under image intensifier guidance. The aims were to assess the duration of pain relief, hand function and range of movement following this procedure...
June 2017: Journal of Hand Surgery Asian-Pacific Volume
https://www.readbyqxmd.com/read/28503046/reflections-about-osteoarthritis-and-curcuma-longa
#12
REVIEW
Marina Cristina Akuri, Sandra Maria Barbalho, Raíssa Meira Val, Elen Landgraf Guiguer
Osteoarthritis (OA) is a chronic inflammatory degenerative process that affects joints such as the hands, hips, shoulders, feet, spine, and especially knees in millions of people worldwide. Some authors have shown that Curcuma longa components may exhibit benefic effects in the treatment of degenerative diseases as OA. This plant belongs to the family Zingiberaceae and it is popularly known as turmeric or saffron. This review intended to perform a retrospective search to identify studies involving humans and animal models...
January 2017: Pharmacognosy Reviews
https://www.readbyqxmd.com/read/28502698/effectiveness-of-a-fine-motor-skills-rehabilitation-program-on-upper-limb-disability-manual-dexterity-pinch-strength-range-of-fingers-motion-performance-in-activities-of-daily-living-functional-independency-and-general-self-efficacy-in-hand-osteoarthritis-a
#13
Jose Manuel Pérez-Mármol, Ma Carmen García-Ríos, María Azucena Ortega-Valdivieso, Enrique Elías Cano-Deltell, María Isabel Peralta-Ramírez, Kelly Ickmans, María Encarnación Aguilar-Ferrándiz
STUDY DESIGN: A randomized clinical trial. INTRODUCTION: Rehabilitation treatments for improving fine motor skills (FMS) in hand osteoarthritis (HOA) have not been well explored yet. PURPOSE OF THE STUDY: To assess the effectiveness of a rehabilitation program on upper limb disability, independence of activities of daily living (ADLs), fine motor abilities, functional independency, and general self-efficacy in older adults with HOA. METHODS: About 45 adults (74-86 years) with HOA were assigned to an experimental group for completing an FMS intervention or a control group receiving conventional occupational therapy...
May 11, 2017: Journal of Hand Therapy: Official Journal of the American Society of Hand Therapists
https://www.readbyqxmd.com/read/28501962/arthrodesis-of-the-thumb-carpometacarpal-joint-using-a-quadrangular-plate-surgical-technique-and-long-term-results-of-70-patients
#14
Verónica Jiménez-Díaz, David Cecilia-López, Miguel Ángel Porras-Moreno, Gema Muñoz-Sánchez, Lorena García-Lamas, Fernando Jara-Sánchez
PURPOSE: To assess the long-term results of trapeziometacarpal arthrodesis using a quadrangular plate, regarding clinical, radiological and functional outcomes, as well as development of complications. MATERIAL AND METHOD: From 2005 to 2015, 70 patients were treated at our institution for primary osteoarthrosis of thumb carpometacarpal joint performing a trapeziometacarpal arthrodesis. A total of 85 arthrodesis were carried out using a titanium quadrangular plate (Proflyle plate, Stryker(®), Kalamazoo MI, USA), without grafting in any case...
May 13, 2017: European Journal of Orthopaedic Surgery & Traumatology: Orthopédie Traumatologie
https://www.readbyqxmd.com/read/28497473/topical-analgesics-for-acute-and-chronic-pain-in-adults-an-overview-of-cochrane-reviews
#15
REVIEW
Sheena Derry, Philip J Wiffen, Eija A Kalso, Rae F Bell, Dominic Aldington, Tudor Phillips, Helen Gaskell, R Andrew Moore
BACKGROUND: Topical analgesic drugs are used for a variety of painful conditions. Some are acute, typically strains or sprains, tendinopathy, or muscle aches. Others are chronic, typically osteoarthritis of hand or knee, or neuropathic pain. OBJECTIVES: To provide an overview of the analgesic efficacy and associated adverse events of topical analgesics (primarily nonsteroidal anti-inflammatory drugs (NSAIDs), salicylate rubefacients, capsaicin, and lidocaine) applied to intact skin for the treatment of acute and chronic pain in adults...
May 12, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28490838/adipokine-contribution-to-the-pathogenesis-of-osteoarthritis
#16
REVIEW
Daniel Azamar-Llamas, Gabriela Hernández-Molina, Bárbara Ramos-Ávalos, Janette Furuzawa-Carballeda
Recent studies have shown that overweight and obesity play an important role in the development of osteoarthritis (OA). However, joint overload is not the only risk factor in this disease. For instance, the presence of OA in non-weight-bearing joints such as the hand suggests that metabolic factors may also contribute to its pathogenesis. Recently, white adipose tissue (WAT) has been recognized not only as an energy reservoir but also as an important secretory organ of adipokines. In this regard, adipokines have been closely associated with obesity and also play an important role in bone and cartilage homeostasis...
2017: Mediators of Inflammation
https://www.readbyqxmd.com/read/28486957/cost-effectiveness-of-surgical-interventions-for-the-management-of-osteoarthritis-a-systematic-review-of-the-literature
#17
Hanin Kamaruzaman, Philip Kinghorn, Raymond Oppong
BACKGROUND: The primary purpose of this study is to assess the existing evidence on the cost-effectiveness of surgical interventions for the management of knee and hip osteoarthritis by systematically reviewing published economic evaluation studies. METHODS: A systematic review was conducted for the period 2004 to 2016. Electronic databases were searched to identify both trial and model based economic evaluation studies that evaluated surgical interventions for knee and hip osteoarthritis...
May 10, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28471034/ultrasonography-detected-subclinical-inflammation-in-patients-with-hand-osteoarthritis-and-established-rheumatoid-arthritis-a-comparison-between-two-different-pathologies-using-the-same-ultrasound-examination-protocol
#18
Sidra Hussain, Priyanka Sivakumaran, Anna Gill, Delfin Dhas, Coziana Ciurtin
OBJECTIVES: A recent review of ultrasound (US) studies in osteoarthritis (OA) showed very limited data about hand OA. Previous US studies in patients with OA described a degree of overlap between the US appearance of rheumatoid arthritis (RA) and OA joints. The present study aimed to assess the US features of subclinical inflammation in RA and hand OA, using the same US examination protocol. METHODS: A retrospective, cohort study compared patients with established RA (n = 224) and hand OA (n = 73), with respect to several demographic, clinical, laboratory and US parameters...
May 4, 2017: Musculoskeletal Care
https://www.readbyqxmd.com/read/28470947/lifetime-risk-of-symptomatic-hand-osteoarthritis-the-johnston-county-osteoarthritis-project
#19
Jin Qin, Kamil E Barbour, Louise B Murphy, Amanda E Nelson, Todd A Schwartz, Charles G Helmick, Kelli D Allen, Jordan B Renner, Nancy A Baker, Joanne M Jordan
OBJECTIVE: Symptomatic hand osteoarthritis (OA) is a common condition that affects hand strength and function, and causes disability in activities of daily living. Prior studies have estimated that the lifetime risk of symptomatic knee OA is 45% and that of hip OA is 25%. The objective of the present study was to estimate the overall lifetime risk of symptomatic hand OA, and the stratified lifetime risk according to potential risk factors. METHODS: Data were obtained from 2,218 adult subjects (ages ≥45 years) in the Johnston County Osteoarthritis Project, a population-based prospective cohort study among residents of Johnston County, North Carolina...
May 4, 2017: Arthritis & Rheumatology
https://www.readbyqxmd.com/read/28467573/the-association-between-self-reported-low-back-pain-and-lower-limb-disability-as-well-as-the-association-between-neck-pain-and-upper-limb-disability
#20
Turhan Kahraman, Evrim Göz, Arzu Genç
OBJECTIVES: To investigate the association between self-reported low back pain (LBP) and lower limb disability as well as the association between neck pain and upper limb disability. METHODS: A hundred twenty-six participants registered as a healthcare staff member were included in this cross-sectional study. The presence of neck and LBP were determined using the Nordic Musculoskeletal Questionnaire. Neck and LBP/disability were measured with the Neck Pain and Disability Scale (NPDS) and Oswestry Disability Index (ODI), respectively...
January 2017: Aǧrı: Ağrı (Algoloji) Derneği'nin Yayın Organıdır, the Journal of the Turkish Society of Algology
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