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https://www.readbyqxmd.com/read/28816972/low-second-to-fourth-digit-ratio-in-dupuytren-disease
#1
Takuya Yokoi, Takuya Uemura, Kenichi Kazuki, Ema Onode, Kosuke Shintani, Mitsuhiro Okada, Hiroaki Nakamura
The ratio of the lengths of the second and fourth digits (2D:4D) has been described as reflecting endogenous prenatal androgen exposure. In general, 2D:4D is lower in men than in women and has potential as a biomarker or predictor for various diseases, athletic ability, and academic performance. Dupuytren disease has digital flexion contractures and is known to predominate in men, but the pathogenesis of the disease remains unclear. To clarify the relationships between Dupuytren disease and endogenous androgens, we performed a retrospective analysis of hand radiographs to investigate 2D:4D in Dupuytren disease...
August 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28816770/prevalence-of-disability-in-patients-with-musculoskeletal-pain-and-rheumatic-diseases-in-a-population-from-cuenca-ecuador
#2
Sergio Vicente Guevara-Pacheco, Astrid Feican-Alvarado, Jorge Delgado-Pauta, Angelita Lliguisaca-Segarra, Ingris Pelaez-Ballestas
OBJECTIVE: The aim of this study was to determine the prevalence of disability in patients with musculoskeletal pain and rheumatic diseases in Cuenca, Ecuador. METHODS: We performed a cross-sectional analytical study with randomized sampling in 4877 subjects, from urban and rural areas. COPCORD (Community Oriented Program for Control of Rheumatic Diseases)-validated questionnaire was administered house-to-house to identify subjects with nontraumatic musculoskeletal pain and rheumatic diseases...
August 14, 2017: Journal of Clinical Rheumatology: Practical Reports on Rheumatic & Musculoskeletal Diseases
https://www.readbyqxmd.com/read/28812414/adipokine-genes-and-radiographic-hand-osteoarthritis-in-finnish-women-a-cross-sectional-study
#3
S Hämäläinen, S Solovieva, T Vehmas, A Hirvonen, P Leino-Arjas
OBJECTIVES: Available evidence suggests that genetic factors and overweight play major roles in the aetiology of osteoarthritis (OA). We analysed the association of 18 single-nucleotide polymorphisms (SNPs) from nine adipokine and adipokine receptor genes (LEP, LEPR, ADIPOQ, RETN, NAMPT, SERPINA12, ITLN1, RARRES2, and APLN) with radiographic hand OA. METHOD: The study design was cross-sectional. Bilateral hand radiographs of 542 occupationally active Finnish female dentists and teachers aged 45-63 years were examined and classified for the presence of hand OA using reference images...
August 16, 2017: Scandinavian Journal of Rheumatology
https://www.readbyqxmd.com/read/28807599/relationship-of-the-patient-specific-functional-scale-to-commonly-used-clinical-measures-in-hand-osteoarthritis
#4
Heidi Hermann Wright, Virginia O'Brien, Kristin Valdes, Barbra Koczan, Joy MacDermid, Elizabeth Moore, Margaret A Finley
STUDY DESIGN: Prospective cohort correlation study. INTRODUCTION: There is no known published research on correlations between the Patient-Specific Functional Scale (PSFS), hand grip strength, and the Disability of the Arm, Shoulder and Hand (DASH) in a population with hand osteoarthritis (OA). PURPOSE: The purpose of this study is to establish reliability of the PSFS and to evaluate the relationship between the PSFS, hand grip strength, and the DASH for a population with hand OA...
August 11, 2017: Journal of Hand Therapy: Official Journal of the American Society of Hand Therapists
https://www.readbyqxmd.com/read/28806829/-lundborg-s-resection-arthroplasty-vs-pyrocarbon-spacer-pyrocardan%C3%A2-for-the-treatment-of-trapeziometacarpal-joint-osteoarthritis-a-two-centre-study
#5
Holger C Erne, Daniel Schmauß, Michael Cerny, Verena Schmauss, Denis Ehrl, Steffen Löw, Stefan Deiler
Background Various operative approaches exist for osteoarthritis of the trapeziometacarpal joint. The aim of this two-centre study was to compare the results of Lundsborg's resection arthroplasty with the implantation of the Pyrocardan(®) spacer. Patients and methods We treated 20 patients with symptomatic osteoarthritis of the trapeziometacarpal joint in stage III / IV (Eaton-Littler classification). Twelve patients received Lundsborg's resection arthroplasty (centre 1), and in 8 patients a Pyrocardan(®) spacer was implanted (centre 2)...
August 2017: Handchirurgie, Mikrochirurgie, Plastische Chirurgie
https://www.readbyqxmd.com/read/28801210/the-longitudinal-relationship-between-hand-hip-and-knee-osteoarthritis-and-cardiovascular-events-a-population-based-cohort-study
#6
T Kendzerska, P Jüni, L K King, R Croxford, I Stanaitis, G A Hawker
OBJECTIVE: In this population-based cohort study, we examined the association between the presence of symptomatic osteoarthritis (OA) and risk for cardiovascular (CV) events. METHOD: A cohort aged ≥55 years recruited from 1996 to 98 was followed through provincial health administrative data to 2014. Demographics, joint complaints and functional limitations were collected. Hip, knee and hand OA were defined using a validated definition. Using Cox-regressions, the relationship between OA and a composite CV outcome (myocardial infarction (MI), stroke, angina, heart failure, revascularization) was assessed controlling for age, body mass index (BMI), sex, pre-existing metabolic factors, comorbidities, income status, primary care exposure and functional limitations...
August 9, 2017: Osteoarthritis and Cartilage
https://www.readbyqxmd.com/read/28799492/potentials-and-limits-of-physiotherapy-in-osteoarthritis
#7
Katrin Richter, Ulf Müller-Ladner, Gabnel Dischereit, Uwe Lange
In view of the already existing and the expected growing costs due to the pathological osteoarthritic joint alterations and the related consequences, preventive and conservative strategies which can avoid or delay osteoarthritic joint alterations are welcomed from a socio-economical perspective. Here, it should be mentioned that corresponding primary prevention measures should take place early by already educating children about a healthy diet and motivating them to regular physical exercise. In overt or symptomatic osteoarthritis a good joint function and reduction of disease-related pain as well as a delay in the progression of osteoarthritis should be the primary goals of non-surgical therapeutic approaches...
August 10, 2017: Current Rheumatology Reviews
https://www.readbyqxmd.com/read/28799491/exercise-programmes-for-osteoarthritis-with-different-localization
#8
Sevdalina Lambova
Therapeutic exercises in osteoarthritis (OA) are therapeutic approach with proven efficacy. On the other hand, the different disease form, the lack of established consensus and system for patient education limit the widespread use of therapeutic exercises in clinical practice. The mechanisms of action of therapeutic exercise in OA include the following components e. g., neuromuscular (improvement of proprioception, muscle strength and joint stability), intra-articular (prevention of cartilage degeneration, antiinflammatory effect, improvement of the quality of the joint fluid), periarticular, general health with reduction of cardiovascular risk and psychological components...
August 10, 2017: Current Rheumatology Reviews
https://www.readbyqxmd.com/read/28795210/-arthrodesis-of-the-trapeziometacarpal-joint
#9
REVIEW
T Pillukat, M Mühldorfer-Fodor, R Fuhrmann, J Windolf, J van Schoonhoven
OBJECTIVE: Bony fusion of the trapeziometacarpal joint. INDICATIONS: High demands concerning stability and strength of the thumb in primary or secondary osteoarthritis (e.g., posttraumatic osteoarthritis following injuries to the carpometacarpal joint of the thumb); instability in the absence of osteoarthritis due to malformations, ligamentous laxicity, and joint hypermobility; malformations; improvement of hand function in neurological disorders; salvage procedure after carpometacarpal arthroplasty provided bone stock is sufficient...
August 9, 2017: Operative Orthopädie und Traumatologie
https://www.readbyqxmd.com/read/28791454/-midcarpal-partial-arthrodesis-with-locking-plate-osteosynthesis
#10
REVIEW
J-F Hernekamp, U Kneser, T Kremer, B Bickert
OBJECTIVE: Preservation of residual mobility and pain reduction in the wrist in advanced carpal collapse (scapholunate advanced collapse, SLAC or scaphoid nonunion advanced collapse, SNAC). INDICATIONS: Advanced osteoarthritis of the radiocarpal and intercarpal articulations, SLAC/SNAC stages 2-3. CONTRAINDICATIONS: Arthrotic alterations to the proximal joint surface of the lunate bone or the corresponding joint surface of the radius (lunate fossa)...
August 8, 2017: Operative Orthopädie und Traumatologie
https://www.readbyqxmd.com/read/28776109/clinical-and-radiological-results-7%C3%A2-years-after-copeland-shoulder-resurfacing-arthroplasty-in-patients-with-primary-glenohumeral-osteoarthritis-an-independent-multicentre-retrospective-study
#11
F U Verstraelen, L A Horta, M G M Schotanus, N P Kort, S K Samijo, E J P Jansen
PURPOSE: The aim of this multicentre cohort study was to evaluate the midterm outcomes and survival after cementless stemless resurfacing arthroplasty (CSRA) in a series of 33 shoulders in 27 patients with primary osteoarthritis. METHODS: Clinical outcome assessment included: Constant-Murley score (CMS); Simple Shoulder Test (SST); Disability of Arm, Shoulder, Hand (DASH); EuroQol-5D (EQ-5D) utility scores; Numerous Rating Scale (NRS) for pain. Radiographs were assessed by two independent observers for oversizing, radiolucency, glenohumeral subluxation, glenoid erosion and subsidence...
August 3, 2017: European Journal of Orthopaedic Surgery & Traumatology: Orthopédie Traumatologie
https://www.readbyqxmd.com/read/28774657/prevalence-of-rheumatic-diseases-in-adult-population-in-spain-episer-2016-study-aims-and-methodology
#12
Daniel Seoane-Mato, Carlos Sánchez-Piedra, Lucía Silva-Fernández, Francisca Sivera, Francisco J Blanco, Fernando Pérez Ruiz, Antonio Juan-Mas, José M Pego-Reigosa, Javier Narváez, Neus Quilis Martí, Raúl Cortés Verdú, Fred Antón-Pagés, Víctor Quevedo Vila, Gustavo Añez Sturchio, Fermín Medina Varo, María Del Mar Ruiz Tudela, Antonio Romero Pérez, Javier Ballina, Anahy Brandy García, Dolores Fábregas Canales, Teresa Font Gayá, Carolina Bordoy Ferrer, Beatriz González Álvarez, Laura Casas Hernández, Fátima Álvarez Reyes, Mónica Delgado Sánchez, Cristina Martínez Dubois, Simón Ángel Sánchez-Fernández, Luisa Marena Rojas Vargas, Paula Virginia García Morales, Alejandro Olivé, Paula Rubio Muñoz, Marta Larrosa, Noemí Navarro Ricos, Eduard Graell Martín, Eugenio Chamizo, Lara Chaves Chaparro, Sara Rojas Herrera, Jordi Pons Dolset, Miguel Ángel Polo Ostariz, Susana Ruiz-Alejos Garrido, Cristina Macía Villa, Ana Cruz Valenciano, María Luisa González Gómez, Mercedes Morcillo Valle, Deseada Palma Sánchez, María José Moreno Martínez, Marta Mayor González, Joana Atxotegi Sáenz de Buruaga, Irati Urionagüena Onaindia, Boris Anthony Blanco Cáceres, Federico Díaz-González, Sagrario Bustabad
AIMS: To describe the methodology of the EPISER 2016 (study of the prevalence of rheumatic diseases in adult population in Spain), as well its strengths and limitations. The aim of this study is to estimate the prevalence of rheumatoid arthritis (RA), psoriatic arthritis (PsA), ankylosing spondylitis (AS), systemic lupus erythematosus (SLE), Sjögren's syndrome (SS), osteoarthritis (knee, hip, hands, and cervical and lumbar spine), fibromyalgia, gout and clinical osteoporotic fracture...
July 31, 2017: Reumatología Clinica
https://www.readbyqxmd.com/read/28774483/clinical-relevance-commentary-in-response-to-effectiveness-of-a-fine-motor-skills-rehabilitation-program-on-upper-limb-disability-manual-dexterity-pinch-strength-range-of-finger-motion-performance-in-activities-of-daily-living-functional-independence-and-general
#13
https://www.readbyqxmd.com/read/28762056/functional-brain-effects-of-hand-disuse-in-patients-with-trapeziometacarpal-joint-osteoarthritis-executed-and-imagined-movements
#14
Martina Gandola, Maurilio Bruno, Laura Zapparoli, Gianluca Saetta, Elena Rolandi, Antonio De Santis, Giuseppe Banfi, Alberto Zerbi, Valerio Sansone, Eraldo Paulesu
The human trapeziometacarpal (TMC) joint has a crucial evolutionary importance as it permits rotation and opposition of the thumb to the other fingers. In chronic TMC joint osteoarthritis (i.e., rhizarthrosis), this motor ability, essential for pinching, grasping, and manipulating objects, may become difficult or impossible due to intolerable pain. Here, we assess whether patients with rhizarthrosis show signs of abnormal brain representation of hand movements. To this end, we studied 35 patients with rhizarthrosis, affecting predominantly one of the two hands, and 35 healthy subjects who underwent both behavioural and fMRI measures of brain activity during overtly executed or imagined thumb-to-finger-opposition movements...
July 31, 2017: Experimental Brain Research. Experimentelle Hirnforschung. Expérimentation Cérébrale
https://www.readbyqxmd.com/read/28752488/wnt-%C3%AE-catenin-signaling-in-osteoarthritis-and-in-other-forms-of-arthritis
#15
REVIEW
Yachuan Zhou, Tingyu Wang, John L Hamilton, Di Chen
PURPOSE OF REVIEW: Arthritis defines a large group of diseases primarily affecting the joint. It is the leading cause of pain and disability in adults. Osteoarthritis (OA) affecting the knee or hip is the most common form among over 100 types of arthritis. Other types of arthritis include erosive hand OA, temporomandibular joint (TMJ) OA, facet joint OA, diffuse idiopathic skeletal hyperostosis (DISH), and spondyloarthritis (SpA). However, the specific molecular signals involved in the development and progression of OA and related forms of arthritis remain largely unknown...
September 2017: Current Rheumatology Reports
https://www.readbyqxmd.com/read/28736908/bmp-7-ameliorates-cobalt-alloy-particle-induced-inflammation-by-suppressing-th17-responses
#16
Fengrong Chen, Ruisong Chen, Haoyuan Liu, Rupeng Sun, Jianming Huang, Zheyuan Huang, Guojian Jian
Metal wear debris has been shown to activate an aseptic osteolytic process that causes failure in total joint arthroplasty (TJA). This osteolysis is characterized by a proinflammatory, self-propagating immune response involving primarily macrophages, dendritic cells, and activated osteoclasts, as well as T cells and B cells. The human bone morphogenic protein (BMP)-7, on the other hand, was shown to promote osteoblast survival, and reversed the downregulation of anabolic Smad proteins and Runx2 following cobalt injury...
July 24, 2017: APMIS: Acta Pathologica, Microbiologica, et Immunologica Scandinavica
https://www.readbyqxmd.com/read/28721601/high-survivorship-and-few-complications-with-cementless-total-wrist-arthroplasty-at-a-mean-followup-of-9-years
#17
Joseph A Gil, Robin N Kamal, Eugene Cone, Arnold-Peter C Weiss
BACKGROUND: Total wrist arthroplasty (TWA) has been described as traditionally being performed with fixation in the radius and carpus with cement. The TWA implant used in our series has been associated with promising results in studies with up to 6 years followup; however, studies evaluating survivorship, pain, and function with this implant are limited. QUESTION/PURPOSE: (1) To report ROM and pain scores after wrist reconstruction with cementless fourth-generation TWA at a mean followup of 9 years (range, 4...
July 18, 2017: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/28721062/the-association-of-adam12-polymorphism-with-osteoarthritis-susceptibility-a-meta-analysis
#18
Zhen Wu, Xin-Wei Xu, Xiao-Wen Zhang
BACKGROUND: The pathology of osteoarthritis (OA) is partly attributed to genetic factors; however, the role of ADAM12 polymorphism is still controversial. It is necessary to perform a meta-analysis to investigate this possible correlation. METHODS: Case-control studies on the association between OA susceptibility and ADAM12 polymorphism were comprehensively collected by searching PubMed, Embase, and Web of Science. Odds ratios (ORs) and 95% confidence intervals (CIs) were pooled to evaluate OA risk that was possibly conferred by ADAM12 variant...
2017: Therapeutics and Clinical Risk Management
https://www.readbyqxmd.com/read/28716512/results-of-the-dubert-procedure-for-chronic-painful-fracture-dislocations-of-the-fifth-carpometacarpal-joint-a-report-of-6-cases
#19
N Meraghni, G Bacle, E Marteau, Y Bouju, J Laulan
Carpometacarpal (CMC) fracture-dislocations of the fifth ray are common. For chronic injuries, Dubert proposed combining resection arthroplasty of the base of the fifth metacarpal (M5) with synostosis with the fourth metacarpal (M4). Our aim was to evaluate the results of this procedure. Between 1994 and 2014, 7 men and 1 woman with an average age of 36 years (range, 27 to 45) were operated on. The right hand was involved in 6 of the 8 cases. All patients had symptomatic osteoarthritis secondary to isolated articular malunion and subluxation of the 5th CMC joint...
July 14, 2017: Hand Surgery and Rehabilitation
https://www.readbyqxmd.com/read/28711879/the-prevalence-incidence-and-progression-of-hand-osteoarthritis-in-relation-to-body-mass-index-smoking-and-alcohol-consumption
#20
Ida K Haugen, Karin Magnusson, Aleksandra Turkiewicz, Martin Englund
OBJECTIVE: To estimate the extent that overweight/obesity, smoking, and alcohol are associated with prevalence and longitudinal changes of radiographic hand osteoarthritis (OA). METHODS: Participants from the Osteoarthritis Initiative (n = 1232) were included, of whom 994 had 4-year followup data. In analyses on incident hand OA, only persons without hand OA at baseline were included (n = 406). Our exposure variables were overweight/obesity [body mass index (BMI), waist circumference], smoking (current/former, smoking pack-yrs), and alcohol consumption (drinks/week)...
July 15, 2017: Journal of Rheumatology
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