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Hand osteoarthritis

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https://www.readbyqxmd.com/read/28624019/scapholunate-dissociation-diagnostics-made-easy
#1
K C A L Cheriex, G S I Sulkers, M P Terra, N W L Schep, B J P L van Aard, S D Strackee
Scapholunate dissociation (SLD) is a form of carpal instability, caused by rupture of the scapholunate ligament (SLL) the secondary stabiliser of the scapholunate (SL) compartment. SLD can cause osteoarthritis of the wrist. Recently a study was published that shows cineradiography to be an excellent radiological imaging technique for diagnosing SLD at a tertiary centre for hand and wrist surgery [1]. As the quality of these results can be influenced by the expertise of the operator and observer of the cineradiographic studies, the aim of this study was to determine if these results were reproducible at a secondary centre for hand and wrist surgery with less expertise in wrist cineradiography...
July 2017: European Journal of Radiology
https://www.readbyqxmd.com/read/28616779/-arthrodesis-of-the-distal-interphalangeal-joint-using-the-headless-compression-screw
#2
REVIEW
C K Spies, B Hohendorff, S Löw, L P Müller, J Oppermann, P Hahn, F Unglaub
OBJECTIVE: Arthrodesis of the distal interphalangeal joint of the fingers and interphalangeal joint of the thumb in order to gain reliable stability and function. INDICATIONS: Primary and secondary osteoarthritis, rheumatoid arthritis, defect lesions, septic joint destruction, posttraumatic joint deviation, fatal joint instability, fatal tendon lesions. CONTRAINDICATIONS: Persistent infections (empyema, osteomyelitis, phlegmon), deficient soft tissue mantle, bone/screw mismatch...
June 14, 2017: Operative Orthopädie und Traumatologie
https://www.readbyqxmd.com/read/28610637/the-effects-of-resistance-training-on-muscle-strength-joint-pain-and-hand-function-in-individuals-with-hand-osteoarthritis-a-systematic-review-and-meta-analysis
#3
Nicoló Edoardo Magni, Peter John McNair, David Andrew Rice
BACKGROUND: Hand osteoarthritis is a common condition characterised by joint pain and muscle weakness. These factors are thought to contribute to ongoing disability. Some evidence exists that resistance training decreases pain, improves muscle strength, and enhances function in people with knee and hip osteoarthritis. However, there is currently a lack of consensus regarding its effectiveness in people with hand osteoarthritis. Therefore, the aim of this systematic review and meta-analysis was to establish whether resistance training in people with hand osteoarthritis increases grip strength, decreases joint pain, and improves hand function...
June 13, 2017: Arthritis Research & Therapy
https://www.readbyqxmd.com/read/28603349/neural-manual-vs-robotic-assisted-mobilization-to-improve-motion-and-reduce-pain-hypersensitivity-in-hand-osteoarthritis-study-protocol-for-a-randomized-controlled-trial
#4
Jorge Hugo Villafañe, Kristin Valdes, Grace Imperio, Alberto Borboni, Raquel Cantero-Téllez, Silvia Galeri, Stefano Negrini
[Purpose] The aim of the present study is to detail the protocol for a randomised controlled trial (RCT) of neural manual vs. robotic assisted on pain in sensitivity as well as analyse the quantitative and qualitative movement of hand in subjects with hand osteoarthritis. [Subjects and Methods] Seventy-two patients, aged 50 to 90 years old of both genders, with a diagnosis of hand Osteoarthritis (OA), will be recruited. Two groups of 36 participants will receive an experimental intervention (neurodynamic mobilization intervention plus exercise) or a control intervention (robotic assisted passive mobilization plus exercise) for 12 sessions over 4 weeks...
May 2017: Journal of Physical Therapy Science
https://www.readbyqxmd.com/read/28602781/systematic-review-of-non-surgical-therapies-for-osteoarthritis-of-the-hand-an-update
#5
REVIEW
S Lue, S Koppikar, K Shaikh, D Mahendira, T E Towheed
OBJECTIVE: To update our earlier systematic reviews which evaluated all published randomized controlled trials (RCTs) evaluating pharmacological and non-pharmacological therapies in patients with hand osteoarthritis (OA). Surgical therapies were not evaluated. DESIGN: RCTs published between March 2008 and December 2015 were added to the previous systematic reviews. RESULTS: A total of 95 RCTs evaluating various pharmacological and non-pharmacological therapies in hand OA were analyzed in this update...
June 15, 2017: Osteoarthritis and Cartilage
https://www.readbyqxmd.com/read/28600494/serum-lipid-levels-and-risk-of-hand-osteoarthritis-the-chingford-prospective-cohort-study
#6
M Garcia-Gil, C Reyes, R Ramos, M T Sanchez-Santos, D Prieto-Alhambra, T D Spector, D J Hart, N K Arden
The development of hand osteoarthritis (HOA) could be linked to hyperlipidaemia. No longitudinal studies have addressed the relationship between serum lipid profile and HOA. The study aim was to determine the association between serum lipid profile and the incidence of radiographic hand osteoarthritis (RHOA). All women in a prospective population-based cohort from the Chingford study with available baseline lipid measurements and without RHOA on a baseline were included. Study outcome was the incidence of RHOA in year 11 of follow-up...
June 9, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28577783/biologic-approaches-to-problems-of-the-hand-and-wrist
#7
REVIEW
Murphy M Steiner, James H Calandruccio
Orthobiologics are not used as frequently in the hand and wrist as in other sites. The most frequently reported is the use of bone morphogenetic protein for the treatment of Kienböck disease. Animal studies have described improved tendon healing with the use of platelet-rich plasma (PRP), but no clinical studies have confirmed these results. PRP has been reported to produce improvements in the outcomes of distal radial fractures and osteoarthritis of the trapeziometacarpal in small numbers of patients. The use of orthobiologics in the hand and wrist are promising, but clinical trials are necessary to establish efficacy and safety...
July 2017: Orthopedic Clinics of North America
https://www.readbyqxmd.com/read/28573370/association-of-tumor-necrosis-factor-%C3%AE-g-308a-genetic-variant-with-matrix-metalloproteinase-9-activity-and-joint-destruction-in-early-rheumatoid-arthritis
#8
Sonja Stojanovic, Bojana Stamenkovic, Tatjana Jevtovic Stoimenov, Jovan Nedovic, Valentina Zivkovic, Milena Despotovic, Dusica Pavlovic
Matrix metalloproteinases (MMPs) are the key enzymes responsible for the joint destruction. Their activity is regulated by the level of proinflammatory cytokines. The aim of this study was to examine the impact of TNF-α G-308A polymorphism on MMP-9 levels in blood plasma (BP) and synovial fluid (SF) of patients with rheumatoid arthritis (RA) and their role in progression of joint destruction. One hundred thirty-four subjects were enrolled in this study. TNF-α G-308A polymorphism was determined using PCR-RFLP method...
June 1, 2017: Clinical Rheumatology
https://www.readbyqxmd.com/read/28567511/trochleoplasty-techniques-provide-good-clinical-results-in-patients-with-trochlear-dysplasia
#9
REVIEW
Umile Giuseppe Longo, Candela Vincenzo, Nicholas Mannering, Mauro Ciuffreda, Giuseppe Salvatore, Alessandra Berton, Vincenzo Denaro
PURPOSE: The aim of this systematic review is to compare the clinical outcomes of patients treated with different trochleoplasty procedures, the rate of complications and recurrence of patellar dislocation. METHODS: A systematic review of the literature was performed, in accord with the PRISMA guidelines. PubMed, MEDLINE, CINAHL, Cochrane, EMBASE and Google Scholar databases were comprehensively searched using the keyword combinations, "Dejour trochleoplasty", "Bereiter Trochleoplasty", "Albee Trochleoplasty", "Recession Trochleoplasty", "Trochlear Dysplasia", "Instability", "Adult", "Clinical Outcome" and "Surgery"...
May 31, 2017: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/28559752/clinical-validation-of-pain-management-manipulative-therapy-for-knee-osteoarthritis-with-the-squeeze-hold-technique-a-case-series
#10
Masaaki Nakajima
OBJECTIVE: The purpose of this case series was to describe the short-term and long-term clinical effects of a manual technique for treating osteoarthritis (OA) knee pain. METHODS: This study measured of the immediate effect and long-term effect by using a case series of different groups of subjects. Knee OA and activity restriction in patients were evaluated by using the Kellgren-Lawrence (K/L) Grading Scale and the Japanese Knee Osteoarthritis Measure (JKOM) index...
June 2017: Journal of Chiropractic Medicine
https://www.readbyqxmd.com/read/28552412/connecting-the-wrist-to-the-hand-a-simulation-study-exploring-changes-in-thumb-tip-endpoint-force-following-wrist-surgery
#11
Jennifer A Nichols, Michael S Bednar, Sarah J Wohlman, Wendy M Murray
The wrist is essential for hand function. Yet, due to the complexity of the wrist and hand, studies often examine their biomechanical features in isolation. This approach is insufficient for understanding links between orthopaedic surgery at the wrist and concomitant functional impairments at the hand. We hypothesize that clinical reports of reduced force production by the hand following wrist surgeries can be explained by the surgically-induced, biomechanical changes to the system, even when those changes are isolated to the wrist...
June 14, 2017: Journal of Biomechanics
https://www.readbyqxmd.com/read/28544753/no-association-between-metabolic-syndrome-and-radiographic-hand-osteoarthritis-data-from-the-framingham-study
#12
Mette P Strand, Tuhina Neogi, Jingbo Niu, David T Felson, Ida K Haugen
OBJECTIVE: To explore whether metabolic syndrome (MetS) and its components are associated with hand OA using longitudinal data from the Framingham study. METHODS: In our cross-sectional analyses we included 1089 persons (age 50-75 years), of whom 785 had 7-year longitudinal radiographs. Of these, 586 with no hand OA at baseline were included in analyses on hand OA incidence. We explored associations between and MetS and its components (central obesity, hypertension, diabetes, triglyceridemia, low high-density lipoprotein) and radiographic hand OA (defined as ≥2 interphalangeal joints with Kellgren-Lawrence grade≥2) using logistic regression analyses with adjustment for age, sex and body mass index (BMI)...
May 23, 2017: Arthritis Care & Research
https://www.readbyqxmd.com/read/28542024/omega-6-omega-3-pufa-ratio-pain-functioning-and-distress-in-adults-with-knee-pain
#13
Kimberly T Sibille, Christopher King, Timothy J Garrett, Toni L Glover, Hang Zhang, Huaihou Chen, Divya Reddy, Burel R Goodin, Adriana Sotolongo, Megan E Petrov, Yenisel Cruz-Almeida, Matthew Herbert, Emily J Bartley, Jeffrey C Edberg, Roland Staud, David T Redden, Laurence A Bradley, Roger B Fillingim
OBJECTIVES: Osteoarthritis (OA) is associated with inflammation, chronic pain, functional limitations, and psychosocial distress. High Omega-3 (n-3) polyunsaturated fatty acids (PUFAs) are associated with lower levels of inflammatory mediators, anti-nociception, and adaptive cognitive/emotional functioning. High Omega-6 (n-6) PUFAs are associated with inflammation, nociception, and psychological distress. While findings related to n-3 supplementation in knee OA are mixed, consideration of the n-6:n-3 ratio and additional outcome measures may provide improved understanding of the potential relevance of these fatty acids in OA...
May 24, 2017: Clinical Journal of Pain
https://www.readbyqxmd.com/read/28536825/intramuscular-clodronate-in-erosive-osteoarthritis-of-the-hand-is-effective-on-pain-and-reduces-serum-comp-a-randomized-pilot-trial-the-er-o-d-e-study-erosive-osteoarthritis-and-disodium-clodronate-evaluation
#14
Gianantonio Saviola, Lul Abdi-Ali, Maria Rosaria Povino, Lorella Campostrini, Silvano Sacco, Luca Dalle Carbonare
We evaluated the efficacy and safety of intramuscular clodronate (CLO) for the treatment of active erosive osteoarthritis of the hand (EOA). Forty outpatients treated with anti-inflammatory (NSAIDs) or analgesic drugs since at least 6 months, for at least 3 days a week, were randomly divided into two groups. Group A: 24 patients treated for 6 months with intramuscular (i.m.) CLO added to usual NSAIDs or analgesic drugs. The attack dose was 200 mg/day i.m. for 10 days followed by a maintenance dose of CLO i...
May 23, 2017: Clinical Rheumatology
https://www.readbyqxmd.com/read/28535729/quantitative-genetics-of-circulating-hyaluronic-acid-ha-and-its-correlation-with-hand-osteoarthritis-and-obesity-related-phenotypes-in-a-community-based-sample
#15
Jai Prakash, Gulzhan Gabdulina, Svetlana Trofimov, Gregory Livshits
BACKGROUND: One of the potential molecular biomarkers of osteoarthritis (OA) is hyaluronic acid (HA). HA levels may be related to the severity and progression of OA. However, little is known about the contribution of major risk factors for osteoarthritis, e.g., obesity-related phenotypes and genetics to HA variation. AIM: To clarify the quantitative effect of these factors on HA. METHODS: An ethnically homogeneous sample of 911 apparently healthy European-derived individuals, assessed for radiographic hand osteoarthritis (RHOA), HA, leptin, adiponectin, and several anthropometrical measures of obesity-related phenotypes...
May 24, 2017: Annals of Human Biology
https://www.readbyqxmd.com/read/28529663/the-modified-dunn-procedure-for-slipped-capital-femoral-epiphysis-the-bernese-experience
#16
M Tannast, L M Jost, T D Lerch, F Schmaranzer, K Ziebarth, K A Siebenrock
PURPOSE: Based on previous investigations on the vascular blood supply to the femoral head, a technique for anatomical reduction after slipped capital femoral epiphysis was developed. This technique is a modification of the original technique by Dunn using a retinacular soft-tissue flap. This allows the visual control of the epiphyseal vascular blood supply. We report the experience at the inventor's institution with a critical discussion of the available literature. METHODS: Using a trochanteric osteotomy for surgical dislocation of the hip, a retinacular soft tissue flap is created containing the deep branch of the medial femoral circumflex artery, the external rotators and the capsule...
April 2017: Journal of Children's Orthopaedics
https://www.readbyqxmd.com/read/28525958/necessity-of-immobilizing-the-metacarpophalangeal-joint-in-carpometacarpal-osteoarthritis-short-term-effect
#17
Raquel Cantero-Téllez, Kristin Valdes, Deborah A Schwartz, Ivan Medina-Porqueres, Jean Christophe Arias, Jorge H Villafañe
BACKGROUND: Conservative treatment for carpometacarpal (CMC) joint osteoarthritis (OA) may include orthotic fabrication to decrease pain. Different types of orthoses have been used as conservative interventions to improve symptoms, but there are no guidelines specifying if inclusion of the thumb metacarpophalangeal (MCP) in an orthosis is required in the treatment of thumb CMC joint OA. The main objective of this study is to determine the effectiveness of 2 different thumb CMC joint orthotic designs on pain reduction and improved hand function: one design immobilizes both the MCP joint and the CMC joint and the other design immobilizes only the CMC joint...
May 1, 2017: Hand: Official Journal of the American Association for Hand Surgery
https://www.readbyqxmd.com/read/28512850/in-situ-handheld-3d-bioprinting-for-cartilage-regeneration
#18
Claudia Di Bella, Serena Duchi, Cathal D O'Connell, Romane Blanchard, Cheryl Augustine, Zhilian Yue, Fletcher Thompson, Christopher Richards, Stephen Beirne, Carmine Onofrillo, Sebastien H Bauquier, Stewart D Ryan, Peter Pivonka, Gordon G Wallace, Peter F Choong
Articular cartilage injuries experienced at an early age can lead to the development of osteoarthritis later in life. In situ 3D printing is an exciting and innovative bio-fabrication technology that enables the surgeon to deliver tissue- engineering techniques at the time and location of need. We have created a hand- held 3D printing device (Biopen) that allows the simultaneous co-axial extrusion of bioscaffold and cultured cells directly into the cartilage defect in vivo in a single session surgery. This pilot study assesses the ability of the Biopen to repair a full thickness chondral defect and the early outcomes in cartilage regeneration, and compares these results to other treatments in a large animal model...
May 17, 2017: Journal of Tissue Engineering and Regenerative Medicine
https://www.readbyqxmd.com/read/28512004/contribution-of-high-resolution-peripheral-quantitative-ct-to-the-management-of-bone-and-joint-diseases
#19
Eric Lespessailles, Nada Ibrahim-Nasser, Hechmi Toumi, Roland Chapurlat
Many imaging modalities have been described to diagnose and monitor osteoporosis (OP), osteoarthritis and inflammatory rheumatic diseases. Over the last ten years, High Resolution peripheral Quantitative Computerized Tomography (HR-pQCT) was shown to be a precise and non invasive technique to study bone and joint diseases in clinical research. It allows the study of both cortical and trabecular bone microarchitecture at the distal tibia and radius, and further applications have been developed such as the study of mechanical properties by the finite element analysis...
May 13, 2017: Joint, Bone, Spine: Revue du Rhumatisme
https://www.readbyqxmd.com/read/28511690/development-of-a-clinical-prediction-algorithm-for-knee-osteoarthritis-structural-progression-in-a-cohort-study-value-of-adding-measurement-of-subchondral-bone-density
#20
Michael P LaValley, Grace H Lo, Lori Lyn Price, Jeffrey B Driban, Charles B Eaton, Timothy E McAlindon
BACKGROUND: Risk prediction algorithms increase understanding of which patients are at greatest risk of a harmful outcome. Our goal was to create a clinically useful prediction algorithm for structural progression of knee osteoarthritis (OA), using medial joint space loss as a proxy; and to quantify the benefit of including periarticular bone mineral density (BMD) in the algorithm. METHODS: Participants were from the Osteoarthritis Initiative (OAI) Progression Cohort, with X-ray readings of medial joint space at 36- and 48-month visits, and a 30- or 36-month medial-to-lateral tibial BMD ratio (M:L BMD ratio) value...
May 16, 2017: Arthritis Research & Therapy
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