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Intravenous fluids for neonates

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https://www.readbyqxmd.com/read/27889725/fluid-supplementation-versus-no-fluid-supplementation-in-late-preterm-and-term-neonates-with-asymptomatic-polycythemia-a-randomized-controlled-trial
#1
Mangalabharathi Sundaram, Sourabh Dutta, Anil Narang
OBJECTIVE: To compare supplemental intravenous fluids with no supplementation in asymptomatic polycythemic late preterm and term neonates. METHODS: 55 infants with venous haematocrit of 65-75 were randomly allocated to receive either 25 mL/kg IV normal saline over 6-8 hours or routine fluids. They were followed up for 48 hours. RESULTS: There was no significant difference between fluid supplementation and control groups regarding need for partial exchange transfusion [6/27 (22...
November 15, 2016: Indian Pediatrics
https://www.readbyqxmd.com/read/27834742/results-of-the-ictus-2-trial-intravascular-cooling-in-the-treatment-of-stroke-2
#2
Patrick Lyden, Thomas Hemmen, James Grotta, Karen Rapp, Karin Ernstrom, Teresa Rzesiewicz, Stephanie Parker, Mauricio Concha, Syed Hussain, Sachin Agarwal, Brett Meyer, Julie Jurf, Irfan Altafullah, Rema Raman
BACKGROUND AND PURPOSE: Therapeutic hypothermia is a potent neuroprotectant approved for cerebral protection after neonatal hypoxia-ischemia and cardiac arrest. Therapeutic hypothermia for acute ischemic stroke is safe and feasible in pilot trials. We designed a study protocol to provide safer, faster therapeutic hypothermia in stroke patients. METHODS: Safety procedures and 4°C saline infusions for faster cooling were added to the ICTuS trial (Intravascular Cooling in the Treatment of Stroke) protocol...
November 10, 2016: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/27810158/clinical-outcomes-associated-with-a-failed-infant-car-seat-challenge
#3
Malika D Shah, Keith A Dookeran, Janine Y Khan
OBJECTIVE: To assess comorbid conditions and clinical outcomes among late preterm and low birth weight term infants (<2.5 kg) who failed the Infant Car Seat Challenge (ICSC) on the Mother-Baby Unit. STUDY DESIGN: This was a retrospective chart review of consecutive infants who failed ICSC on the Mother-Baby Unit and were subsequently admitted to the neonatal intensive care unit at Prentice Women's Hospital between January 1, 2009, and December 31, 2015. Regression models were used to estimate risk differences (RDs) with 95% CIs for factors related to length of stay...
October 31, 2016: Journal of Pediatrics
https://www.readbyqxmd.com/read/27800071/neonatal-transport-practices-in-ibadan-nigeria
#4
Muhydeen Abiodun Abdulraheem, Olukemi Oluwatoyin Tongo, Adebola Emmanuel Orimadegun, Olukayode Felix Akinbami
INTRODUCTION: Neonatal transport involves moving sick neonates in optimal conditions to ensure good outcomes. It is well organized in most developed countries but receives little attention in developing countries where the highest burden of neonatal mortality exists and a large number of newborns require referrals daily for better medical care. This study sought to evaluate the modes of transport, pre- and intra-transport care of neonates referred to the University College Hospital (UCH), Ibadan, Nigeria...
2016: Pan African Medical Journal
https://www.readbyqxmd.com/read/27792444/in-line-pressure-monitoring-in-iv-infusions-benefits-for-patients-and-nurses
#5
Scott M Gouveia
Intravenous (IV) infusions are an essential part of hospital patient care, but occlusions in peripheral cannulae are common. One of the most dangerous consequences of occlusion (blockage) is extravasation-the non-intentional leakage of infused vesicant fluid into the tissue surrounding the vein-as it can lead to long-term, or even permanent, tissue damage. Adults and children are affected, with preterm neonates being particularly vulnerable. In-line pressure monitoring (ILPM) can help identify occlusions early and help prevent complications such as extravasation and infiltration...
October 27, 2016: British Journal of Nursing: BJN
https://www.readbyqxmd.com/read/27788744/-clinical-analysis-of-19-cases-of-pregnant-women-with-rapid-arrhythmia-in-the-treatment-of-radiofrequency-catheter-ablation
#6
L Chu, J Zhang, Y N Li, D Y Long
: Objective: To investigate the risk of radiofrequency catheter ablation and maternal and infant in pregnant women with rapid arrhythmia during pregnancy. Methods: The clinical data of the 19 cases of pregnancy complicated with rapid arrhythmia were retrospectively analyzed and followed up, including the gestational week, the type of arrhythmia, the treatment, and the outcome of the mother and child in Beijing Anzhen Hospital of Capital Medical University from January 2002 to March 2016...
October 25, 2016: Zhonghua Fu Chan Ke za Zhi
https://www.readbyqxmd.com/read/27697761/high-dose-micafungin-for-preterm-neonates-and-infants-with-invasive-and-central-nervous-system-candidiasis
#7
Cinzia Auriti, Marco Falcone, Maria Paola Ronchetti, Bianca Maria Goffredo, Sara Cairoli, Rosamaria Crisafulli, Fiammetta Piersigilli, Tiziana Corsetti, Andrea Dotta, Manjunath P Pai
High doses of micafungin are advocated in neonates with systemic candidiasis but limited pharmacokinetic (PK) and safety data are available to support their use. Eighteen preterm neonates and infants with systemic candidiasis, 3 with meningitis, were treated for at least 14 days with 8 to 15 mg/kg/day of intravenous micafungin. Plasma concentrations (4 measurements) were determined after the third dose and cerebrospinal-fluid (CSF) concentrations were also obtained in three patients. Population PK analyses were used to identify the optimal model and further validated using external data (n=5)...
October 3, 2016: Antimicrobial Agents and Chemotherapy
https://www.readbyqxmd.com/read/27695644/neonatal-enterovirus-infection-case-series-of-clinical-sepsis-and-positive-cerebrospinal-fluid-polymerase-chain-reaction-test-with-myocarditis-and-cerebral-white-matter-injury-complications
#8
Frank H Morriss, Julie B Lindower, Heather L Bartlett, Dianne L Atkins, Jean O Kim, Jonathan M Klein, Bradley A Ford
Objective We describe five neonates with enteroviral (EV) infection to demonstrate central nervous system (CNS) and cardiac complications and report successful treatment of myocarditis with immunoglobulin intravenous (IVIG) in two. Study Design Case series identified during three enteroviral seasons in one neonatal intensive care unit (NICU) by cerebral spinal fluid (CSF) reverse transcriptase polymerase chain reaction (PCR) testing for EV in neonates suspected to have sepsis, but with sterile bacterial cultures...
July 2016: American Journal of Perinatology Reports
https://www.readbyqxmd.com/read/27550159/parental-hopes-interventions-and-survival-of-neonates-with-trisomy-13-and-trisomy-18
#9
Annie Janvier, Barbara Farlow, Keith J Barrington
Trisomy 13 and 18 are life-limiting conditions for which a palliative approach is frequently recommended. The objective of this study was to examine parental goals/decisions, the length of life of their child and factors associated with survival. Parents of children who lived with trisomy 13 or 18 that were part of English-speaking social networks were invited to participate in a questionnaire study. Participants answered questions about their hopes/goals, decisions regarding neonatal interventions, and the duration of their children's lives...
September 2016: American Journal of Medical Genetics. Part C, Seminars in Medical Genetics
https://www.readbyqxmd.com/read/27524291/standard-concentration-infusions-in-paediatric-intensive-care-the-clinical-approach
#10
Joanne Perkins, Virginia Aguado-Lorenzo, Sara Arenas-Lopez
: The use of standard concentrations of intravenous infusions has been advocated by international organisations to increase intravenous medication safety in paediatric and neonatal critical care. However, there is no guidance on how to identify and implement these infusions leading to great interunit variability. OBJECTIVE: To identify the most appropriate clinical concentrations required by our paediatric intensive care unit (PICU) population with regard to accuracy of delivery and overall fluid allowance...
August 14, 2016: Journal of Pharmacy and Pharmacology
https://www.readbyqxmd.com/read/27521143/repackaging-of-intravenous-fat-emulsions-a-clinical-conundrum
#11
M Petrea Cober
To accommodate small fluid volumes, repackaging of intravenous fat emulsions (IVFEs) is frequently performed in institutions providing parenteral nutrition to neonates and smaller pediatric patients. However, some consider this an unsafe practice. Concerns for potential administration errors leading to an overdose of IVFEs are weighed against the potential for microbial contamination from the repackaging process. The clinician providing pediatric nutrition support should tailor repackaging practices to ensure patient safety and quality...
October 2016: Nutrition in Clinical Practice
https://www.readbyqxmd.com/read/27429567/nontherapeutic-neonatal-hypothermia
#12
Michael Sgro, Douglas M Campbell, Neil Gandhi
The case presented advocates for prolonged resuscitation, and aggressive rewarming in neonates with severe hypothermia (core temperature <32.0°C). The importance of rewarming has not been extensively studied in current guidelines, whereas the importance of cardiopulmonary resuscitation is well established. This abandoned, severely hypothermic (found with temperature of 27.9°C) newborn had an excellent neurological outcome at two years of age with aggressive resuscitation and rewarming techniques initiated at the time of presentation...
May 2016: Paediatrics & Child Health
https://www.readbyqxmd.com/read/27399029/calcaneus-osteomyelitis-secondary-to-guthrie-test-case-report
#13
Tugce Tural Kara, Tugba Erat, Halil Ozdemir, Aysun Yahsi, Suat Fitoz, Ergin Ciftci, Erdal Ince
Calcaneus osteomyelitis is a rare infection in newborns. Invasive procedures, prematurity and low birth wight are some causative factors. The clinical signs may be mild. We report a neonate with calcaneous osteomyelitis which was secondary to a Guthrie test sample. She was admitted to hospital with swelling, redness and increased temperature on her heel. Superficial tissue ultrasound showed fluid collection with heavy content was observed on the posterior of the right foot. Puncture and drainage was performed and methicillin-susceptible Staphylococcus aureus was isolated from the drainage culture...
August 1, 2016: Archivos Argentinos de Pediatría
https://www.readbyqxmd.com/read/27391563/first-golden-hour-of-life-a-quality-improvement-initiative
#14
Tinisha M Lambeth, Mario A Rojas, Amy P Holmes, Robin B Dail
BACKGROUND: Very low birth-weight (<1500 g) infants are vulnerable to their environment during the first hour after birth. We designed an evidence-based golden hour protocol (GHP) with a goal to stabilize and perform admission procedures within 1 hour of birth at a level IIIB neonatal intensive care unit (NICU). PURPOSE: The aim of this quality improvement project was to ascertain whether an evidence-based GHP would improve care efficiency and short-term outcomes...
August 2016: Advances in Neonatal Care: Official Journal of the National Association of Neonatal Nurses
https://www.readbyqxmd.com/read/27168518/interventions-for-treating-hyperemesis-gravidarum
#15
REVIEW
Rupsa C Boelig, Samantha J Barton, Gabriele Saccone, Anthony J Kelly, Steve J Edwards, Vincenzo Berghella
BACKGROUND: Hyperemesis gravidarum is a severe form of nausea and vomiting in pregnancy affecting 0.3% to 1.0% of pregnancies, and is one of the most common indications for hospitalization during pregnancy. While a previous Cochrane review examined interventions for nausea and vomiting in pregnancy, there has not yet been a review examining the interventions for the more severe condition of hyperemesis gravidarum. OBJECTIVES: To assess the effectiveness and safety, of all interventions for hyperemesis gravidarum in pregnancy up to 20 weeks' gestation...
2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27088020/a-lethal-case-of-sphingomonas-paucimobilis-bacteremia-in-an-immunocompromised-patient
#16
Nata Pratama Hardjo Lugito, Cucunawangsih, Andree Kurniawan
Sphingomonas paucimobilis is a yellow-pigmented, glucose nonfermenting, aerobic, Gram negative bacillus of low pathogenicity. This organism was found in the implantation of indwelling catheters, sterile intravenous fluid, or contaminated hospital environment such as tap and distilled water, nebulizer, ventilator, and hemodialysis device. A 55-year-old female was hospitalized for diabetic foot ulcer in the presence of multiple comorbidities: diabetes mellitus, colonic tuberculosis, end-stage renal disease, and indwelling catheters for central venous catheter and hemodialysis...
2016: Case Reports in Infectious Diseases
https://www.readbyqxmd.com/read/27066799/infected-cephalohematomas-and-underlying-osteomyelitis-a-case-based-review
#17
Michael D Staudt, Daniel Etarsky, Adrianna Ranger
BACKGROUND: Cephalohematomas are relatively common sub-periosteal collections of blood that tend to resolve spontaneously without treatment. Rarely, they become infected and can be associated with underlying osteomyelitis, meningitis, or sepsis. Common pathogens include Escherichia coli and Staphylococcus species. ILLUSTRATIVE CASE: This report describes the first case of a neonate developing an infected right parietal cephalohematoma and underlying osteomyelitis caused by Morganella morganii, which was cultured in blood and cephalohematoma aspirate...
August 2016: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
https://www.readbyqxmd.com/read/27056029/parenteral-nutrition-solution-in-cerebrospinal-fluid-in-preterm-newborn-a-case-report-and-review-of-the-literature
#18
Monika Lachowska, Krzysztof Lachowski, Barbara Królak-Olejnik
INTRODUCTION: Percutaneously inserted central venous catheters (epicutaneo-cava-catheter - ECC) are widely used in neonatal intensive care, facilitating the parenteral nutrition and the treatment of critically ill newborns. This invasive procedure is regarded as safe and associated with low complication rate. Possible life-threatening complications may result from malpositioning of ECC. Paraspinal misplacement of ECC is one of the most serious complications. CASE PRESENTATION: The authors report a case of misplacement of ECC inserted via left saphenous vein for intravenous feeding...
2016: Journal of Vascular Access
https://www.readbyqxmd.com/read/27031053/feeding-during-blood-transfusions-and-the-association-with-necrotizing-enterocolitis
#19
Megan Doty, Christine Wade, Julie Farr, Vanessa Celleri Gomezcoello, Gregory Martin, Tala Nasr
Objective The aim of this study was to determine whether very low-birth-weight (VLBW) infants who had feedings withheld during all blood transfusions had a lower incidence of necrotizing enterocolitis (NEC) compared with infants who were fed during transfusions. Study Design A retrospective chart review over a 3-year period in a level-3 neonatal intensive care unit was conducted. A total of 108 inborn VLBW infants (weight range: 500-1,500 g) who had received a transfusion before 36 weeks were reviewed. Diagnosis of NEC (≥ Bell stage II), demographics, feeds, transfusions, outcomes, and variables associated with NEC were collected...
July 2016: American Journal of Perinatology
https://www.readbyqxmd.com/read/26954534/intravenous-fluid-bolus-prior-to-neonatal-and-infant-lumbar-puncture-a-sonographic-assessment-of-the-subarachnoid-space-after-intravenous-fluid-administration
#20
Jessica Rankin, Vincent J Wang, Fariba Goodarzian, Hollie A Lai
IMPORTANCE: Neonatal and infant lumbar puncture is a commonly performed procedure in emergency departments, yet traumatic and unsuccessful lumbar punctures occur 30% to 50% of the time. Dehydration may be a risk factor for unsuccessful lumbar punctures, but to our knowledge, no studies have investigated the use of intravenous (IV) fluid bolus prior to lumbar puncture. OBJECTIVE: To investigate the association of IV fluid bolus administration with the sonographic measure of the neonatal and infant lumbar subarachnoid space...
March 2016: JAMA Pediatrics
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