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Mohammad Reza Akbari

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https://www.readbyqxmd.com/read/29883970/the-effects-of-vitamin-d-supplementation-on-biomarkers-of-inflammation-and-oxidative-stress-in-diabetic-patients-a-systematic-review-and-meta-analysis-of-randomized-controlled-trials
#1
Mohammad Ali Mansournia, Vahidreza Ostadmohammadi, Amin Doosti-Irani, Majid Ghayour-Mobarhan, Gordon Ferns, Hossein Akbari, Amir Ghaderi, Hamid Reza Talari, Zatollah Asemi
In this systematic review and meta-analysis of randomized controlled trials (RCTs), the effects of vitamin D supplementation on biomarkers of inflammation and oxidative stress in diabetic patients are summarized. The following databases were searched up to December 2017: MEDLINE, EMBASE, Web of Science, and Cochrane Central Register of Controlled Trials. The quality of the relevant extracted data was assessed according to the Cochrane risk of bias tool. Data were pooled using the inverse variance method and expressed as mean difference with 95% Confidence Intervals (95% CI)...
June 2018: Hormone and Metabolic Research, Hormon- und Stoffwechselforschung, Hormones et Métabolisme
https://www.readbyqxmd.com/read/29805453/factitious-hypoglycemia-caused-by-a-unique-pattern-of-drug-use-a-case-report
#2
Mojtaba Akbari, Akbar Soltani, Mohammad Reza Mohajeri-Tehrani, Hamidreza Aghaei Meybodi, Imaneh Sadat Mousavi Fakhr, Sayed Mahmoud Sajjadi-Jazi
Introduction: Factitious hypoglycemia, caused by the surreptitious use of insulin and sulfonylureas, is one of the most challenging differential diagnoses of hypoglycemia. Diagnosis is usually established via exclusion with respect to the special patterns of plasma insulin and C-peptide during hypoglycemic episodes. Case Presentation: We report a case of recurrent hypoglycemic episodes and confusing patterns of insulin and C-peptide levels. In the primary evaluations, insulinoma was suspected considering the high plasma concentrations of insulin and C-peptide, besides negative urine and plasma sulfonylureas during hypoglycemic episodes...
January 2018: International Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29800125/health-in-all-policies-hiap-governance-lessons-from-network-governance
#3
Akram Khayatzadeh-Mahani, Arne Ruckert, Ronald Labonté, Patrick Kenis, Mohammad Reza Akbari-Javar
The Health in All Policies (HiAP) approach requires formal and sustained governance structures and mechanisms to ensure that the policies of various non-health sectors maximize positive and minimize negative impacts on population health. In this paper, we demonstrate the usefulness of a network perspective in understanding and contributing to the effectiveness of HiAP. We undertook an exploratory, qualitative case study of a HiAP structure in Iran, the Kerman province Council of Health and Food Security (CHFS) with diverse members from health and non-health sectors...
May 25, 2018: Health Promotion International
https://www.readbyqxmd.com/read/29749981/high-prevalence-of-vitamin-d-deficiency-among-iranian-population-a-systematic-review-and-meta-analysis
#4
REVIEW
Reza Tabrizi, Mahmood Moosazadeh, Maryam Akbari, Mohammad Hossein Dabbaghmanesh, Minoo Mohamadkhani, Zatollah Asemi, Seyed Taghi Heydari, Mojtaba Akbari, Kamran B Lankarani
Background: The prevention and correction of vitamin D deficiency requires a precise depiction of the current situation and identification of risk factors in each region. The present study attempted to determine these entities using a systematic review and meta-analysis in Iran. Methods: Articles published online in Persian and English between 2000 and November 1, 2016, were reviewed. This was carried out using national databases such as SID, IranMedex, Magiran, and IranDoc and international databases such as PubMed, Google Scholar, and Scopus...
March 2018: Iranian Journal of Medical Sciences
https://www.readbyqxmd.com/read/29741767/down-regulation-of-intracellular-anti-apoptotic-proteins-particularly-c-flip-by-therapeutic-agents-the-novel-view-to-overcome-resistance-to-trail
#5
REVIEW
Ali Hassanzadeh, Majid Farshdousti Hagh, Mohammad Reza Alivand, Ali Akbar Movassaghpour Akbari, Karim Shams Asenjan, Raedeh Saraei, Saeed Solali
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL or Apo2L) is a member of the tumor necrosis factor (TNF) superfamily that induces apoptosis in different types of cancer cells via activation of caspase cascade. TRAIL interacts with its cognate receptors that placed on cancer cells surface, including TRAIL-R1 (death receptor 4, DR4), TRAIL-R2 (death receptor 5, DR5), TRAIL-R3 (decoy receptor 1, DcR1), TRAIL-R4 (decoy receptor 2, DcR2), and osteoprotegerin (OPG). Despite high apoptosis-inducing ability of TRAIL, various cancerous cells gain resistance to TRAIL gradually, and consequently TRAIL potential for apoptosis stimulation in these cells diminishes intensely...
May 9, 2018: Journal of Cellular Physiology
https://www.readbyqxmd.com/read/29664314/iran-pituitary-tumor-registry-description-of-the-program-and-initial-results
#6
Mohammad Ebrahim Khamseh, Mohammad Reza Mohajeri Tehrani, Zohreh Mousavi, Mojtaba Malek, Mehrnaz Imani, Nasim Hoshangian Tehrani, Mohammad Ghorbani, Hamideh Akbari, Farzaneh Sarvghadi, Atieh Amouzegar, Fatemeh Esfahanian, Nahid Hashemi Madani, Zahra Emami
BACKGROUND: This study was designed to present initial results on clinical presentation, therapeutic modalities, and outcome information of patients with pituitary tumors registered in Iran Pituitary Tumor Registry (IPTR). METHODS: We collected data from a web-based electronic medical records of patients with various pituitary tumors referred to four tertiary care centers in the country. Retrospective analysis was performed on demographic, clinical, and therapeutic information of 298 patients including 51 clinically nonfunctioning adenoma (CNFA), 85 acromegaly, 135 prolactinoma, and 27 Cushing's disease (CD)...
December 31, 2017: Archives of Iranian Medicine
https://www.readbyqxmd.com/read/29510849/anti-vibriocholerae-igy-antibody-inhibits-mortality-in-suckling-mice-model
#7
Mohammad Reza Akbari, Ali Ahmadi, Shiva Mirkalantari, Jafar Salimian
BACKGROUND: Regarding to the importance of cholera in Iran and the potential advantages of egg yolk antibody (IgY) for immunotherapy, the aim of this study was to produce IgY antibody against V. cholerae Lipopolysaccharide (LPS) and determine its potential for V. cholerae treatment. METHODS: LPS was prepared, and the Anti-V. cholerae LPS IgY was purified from egg yolk and serially diluted in phosphate-buffered saline (PBS), mixed with V. cholerae and then gavaged into several groups of suckling mice...
February 2018: Journal of the National Medical Association
https://www.readbyqxmd.com/read/29494263/clinical-and-histopathologic-features-of-consecutive-exotropia
#8
Mohammad Reza Akbari, Narges Hassanpoor, Masoud Aghsaei Fard, Zohreh Nozarian, Mehdi Yaseri, Arash Mirmohammadsadeghi
PURPOSE: The purpose of this study is to investigate clinical and histopathologic features of consecutive exotropia. METHODS: Thirty patients with consecutive exotropia and negative forced duction testing underwent unilateral medial rectus resection and advancement. Abnormal scleral attachment (appearance of stretched scar or slipped muscle) was documented and compared with histopathology results. The term "stretched scar" is used when tendon-like scar appears between muscle fibers and scleral attachment...
March 1, 2018: Strabismus
https://www.readbyqxmd.com/read/29426796/road-traffic-deaths-in-kashan-region-iran-an-eight-year-study-2006-2013
#9
Mehrdad Mahdian, Mojtaba Sehat, Mohammad Reza Fazel, Hossein Akbari, Habibollah Rahimi, Mahdi Mohammadzadeh
PURPOSE: The aim of this study was to analyze the trend of road traffic fatalities in Kashan Region, Iran, in a period of eight years. METHODS: Through a cross-sectional study, all road traffic deaths classified under the V01V99 codes according to ICD-10 in Kashan region, central Iran, from March 2006 to March 2013 and population data were collected from the registration system of Kashan University of Medical Sciences. Years of lost life (YLL) and mortality rates were calculated regarding age, gender and year of the accident...
February 2018: Chinese Journal of Traumatology, Zhonghua Chuang Shang za Zhi
https://www.readbyqxmd.com/read/29408778/increased-serum-levels-of-tnf-%C3%AE-and-decreased-serum-levels-of-il-27-in-patients-with-parkinson-disease-and-their-correlation-with-disease-severity
#10
Ebrahim Kouchaki, Reza Daneshvar Kakhaki, Omid Reza Tamtaji, Ehsan Dadgostar, Mohammad Behnam, Hassan Nikoueinejad, Hossein Akbari
OBJECTIVES: Immunological basis of neurodegenerative diseases including Alzheimer and Parkinson disease (PD) has some important roles in their pathogenesis. There are conflicting studies to serum level of TNF-α in PD. Also, according to our finding there is no report evaluating serum level of IL-27 in PD. This study correlates the serum level of those factors with severity of PD. PATIENTS AND METHODS: In this case-control study, 83 patients with PD and 83 healthy volunteers were enrolled...
March 2018: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/29302074/genetics-of-intellectual-disability-in-consanguineous-families
#11
Hao Hu, Kimia Kahrizi, Luciana Musante, Zohreh Fattahi, Ralf Herwig, Masoumeh Hosseini, Cornelia Oppitz, Seyedeh Sedigheh Abedini, Vanessa Suckow, Farzaneh Larti, Maryam Beheshtian, Bettina Lipkowitz, Tara Akhtarkhavari, Sepideh Mehvari, Sabine Otto, Marzieh Mohseni, Sanaz Arzhangi, Payman Jamali, Faezeh Mojahedi, Maryam Taghdiri, Elaheh Papari, Mohammad Javad Soltani Banavandi, Saeide Akbari, Seyed Hassan Tonekaboni, Hossein Dehghani, Mohammad Reza Ebrahimpour, Ingrid Bader, Behzad Davarnia, Monika Cohen, Hossein Khodaei, Beate Albrecht, Sarah Azimi, Birgit Zirn, Milad Bastami, Dagmar Wieczorek, Gholamreza Bahrami, Krystyna Keleman, Leila Nouri Vahid, Andreas Tzschach, Jutta Gärtner, Gabriele Gillessen-Kaesbach, Jamileh Rezazadeh Varaghchi, Bernd Timmermann, Fatemeh Pourfatemi, Aria Jankhah, Wei Chen, Pooneh Nikuei, Vera M Kalscheuer, Morteza Oladnabi, Thomas F Wienker, Hans-Hilger Ropers, Hossein Najmabadi
Autosomal recessive (AR) gene defects are the leading genetic cause of intellectual disability (ID) in countries with frequent parental consanguinity, which account for about 1/7th of the world population. Yet, compared to autosomal dominant de novo mutations, which are the predominant cause of ID in Western countries, the identification of AR-ID genes has lagged behind. Here, we report on whole exome and whole genome sequencing in 404 consanguineous predominantly Iranian families with two or more affected offspring...
January 4, 2018: Molecular Psychiatry
https://www.readbyqxmd.com/read/29184648/estimating-the-prevalence-of-positive-tuberculin-skin-test-reactions-in-general-population-and-high-risk-groups-a-meta-analysis
#12
REVIEW
Mohammad Sadegh Rezai, Reza Tabrizi, Ali Akbar Haghdoost, Mahdi Afshari, Siavosh Abedi, Maryam Akbari, Mohammad Amin Bahrami, Mahmood Moosazadeh
Results of tuberculin skin test (TST) surveys among different populations have been reported in many studies as a method for detecting primary Mycobacterium tuberculosis infection. Combining these results provides reliable estimates of primary latent tuberculosis (TB) infection for health policymakers. This study aims to estimate the prevalence of latent TB infection in general and high-risk populations in Iran. National and international databanks were searched using specific keywords. After restricting the search strategy, duplicates exclusion, reviewing titles, abstracts and full texts, and quality assessment, eligible papers were selected...
2017: International Journal of Preventive Medicine
https://www.readbyqxmd.com/read/29080617/wash-resistance-and-bio-efficacy-of-olyset-%C3%A2-plus-a-long-lasting-insecticide-treated-mosquito-net-with-synergist-against-malaria-vector-anopheles-stephensi
#13
Soraya Sheikhi, Hassan Vatandoost, Mohammad Reza Abai, Mansoreh Shayeghi, Ahmad Raeisi, Morteza Akbari, Fatemeh Nikpoor, Mohammad Sistanizade Aghdam, Akbar Bagheri
OBJECTIVE: To determine the wash resistance of Olyset® Plus using World Health Organization Pesticide Evaluation Scheme standard washing procedure and to assess the value of knock down and mortality rates of Anopheles stephensi at different regimens of long lasting insecticide treated nets washings. METHODS: The study was conducted at the Bioassay Laboratory of Culicidae Insectary, School of Public Health, Tehran University of Medical Sciences, Iran. The net was made of polyester impregnated with permethrin and piperonyl butoxide at a ratio of 2:1...
September 2017: Asian Pacific Journal of Tropical Medicine
https://www.readbyqxmd.com/read/29048924/de-novo-mutation-in-cacna1s-gene-in-a-20-year-old-man-diagnosed-with-metabolic-myopathy
#14
Masoud Edizadeh, Raheleh Vazehan, Fatemeh Javadi, Shima Dehdahsi, Mahsa Fadaee, Mehrshid Faraji Zonooz, Elham Parsimehr, Fatemeh Ahangari, Ayda Abolhassani, Zahra Kalhor, Zohreh Fattahi, Maryam Beheshtian, Ariana Kariminejad, Mohammad Reza Akbari, Hossein Najmabadi, Shahriar Nafissi
The calcium channel, voltage-dependent, L-type, alpha 1S subunit (CACNA1S) gene encodes a skeletal Ca2+ channel which is involved in calcium-dependent processes such as muscle contraction and neurotransmitter release. Mutations in this gene have been accompanied by hypo- and normokalemic periodic paralysis, thyrotoxic periodic paralysis, and susceptibility to malignant hyperthermia. We report the clinical and genetic findings in a patient diagnosed with metabolic myopathy who had episodic attacks of muscle pain and weakness but with no family background of the disease...
September 2017: Archives of Iranian Medicine
https://www.readbyqxmd.com/read/29037659/the-accuracy-of-wide-field-ultrasound-biomicroscopy-in-localizing-extraocular-rectus-muscle-insertions-in-strabismus-reoperations
#15
Arash Mirmohammadsadeghi, Vahideh Manuchehri, Mohammad Reza Akbari
PURPOSE: To compare the accuracy of widefield ultrasound biomicroscopy (UBM) with mechanical intraoperative measurements of the distance between rectus muscle insertions and the corneal limbus in strabismus reoperations. METHODS: Subjects with a history of horizontal rectus muscle surgery who required further surgery on horizontal rectus muscle(s) were recruited prospectively. All widefield UBM measurements were carried out under topical anesthesia using a 50 MHz linear probe without immersion cup and external caliper...
December 2017: Journal of AAPOS: the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus
https://www.readbyqxmd.com/read/28916975/flaxseed-oil-supplementation-improve-gene-expression-levels-of-ppar-%C3%AE-lp-a-il-1-and-tnf-%C3%AE-in-type-2-diabetic-patients-with-coronary-heart-disease
#16
Ali Akbar Hashemzadeh, Nikoo Nasoohi, Fariba Raygan, Esmat Aghadavod, Elmira Akbari, Mohsen Taghizadeh, Mohammad Reza Memarzadeh, Zatollah Asemi
This study was carried out to determine the effects of flaxseed oil administration on gene expression levels related to insulin, lipid and inflammation in overweight diabetic patients with coronary heart disease (CHD). This randomized double-blind, placebo-controlled trial was conducted among 60 diabetic patients with CHD. Subjects were randomly allocated into two groups to intake either 1000 mg n-3 fatty acid from flaxseed oil containing 400 mg α-Linolenic acid [ALA (18:3n-3)] (n = 30) or placebo (n = 30) twice a day for 12 weeks...
November 2017: Lipids
https://www.readbyqxmd.com/read/28913515/paradoxical-head-tilt-in-unilateral-traumatic-superior-oblique-palsy
#17
Mohammad Reza Akbari, Reza Bayat, Arash Mirmohammadsadeghi, Reza Mirshahi
PURPOSE: We report a patient with abnormal head posture following ocular blunt trauma. METHODS: This is report of a case that despite findings compatible with diagnosis of left superior oblique (SO) palsy, the patient acquired an ipsilateral (left) head tilt. The interesting observation in our patient was reduction of left hypertropia and consequent less diplopia with ipsilateral head tilt. RESULTS: After blunt trauma, our patient adopted paradoxical left head tilt and consequently less diplopia despite acquired left SO palsy...
September 2017: Journal of Current Ophthalmology
https://www.readbyqxmd.com/read/28875319/kisspeptin-expression-features-in-the-arcuate-and-anteroventral-periventricular-nuclei-of-hypothalamus-of-letrozole-induced-polycystic-ovarian-syndrome-in-rats
#18
Elham Aliabadi, Mohammad Reza Namavar, Keywan Mortezaee, Heidar Toolee, Sara Keshtgar, Hossein Mirkhani, Mohammad Akbari, Tayebeh Rastegar, Somayeh Solhjoo
PURPOSE: Polycystic ovary syndrome (PCOS) is the most common endocrine disorder of the reproductive system characterized by polycystic ovaries and androgen excess. Letrozole is a nonsteroidal aromatase inhibitor that is used in experimental research to induce PCOS. Kisspeptin is an essential protein in regulation of cyclicity. Kisspeptin receptor is expressed in the hypothalamus and pituitary glands, and kisspeptin containing neurons are affected from sex steroid hormones. We aimed to investigate the number of kisspeptin-positive cells in the arcuate (Arc) and anteroventral periventricular nuclei (AVPV) of hypothalamus in the letrozole-induced PCOS...
November 2017: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/28865413/correlation-of-serum-levels-of-il-33-il-37-soluble-form-of-vascular-endothelial-growth-factor-receptor-2-vegfr2-and-circulatory-frequency-of-vegfr2-expressing-cells-with-multiple-sclerosis-severity
#19
Ebrahim Kouchaki, Omid Reza Tamtaji, Ehsan Dadgostar, Mohammad Karami, Hassan Nikoueinejad, Hossein Akbari
IL-33 and IL-37 (new cytokines of IL-1 family), soluble form of vascular endothelial growth factor receptor-2 (sVEGFR2) as well as membranous expression of VEGFR2 have some key roles in the pathogenesis of autoimmune and inflammatory diseases. The aim of this study was to correlate circulatory changes of these factors with the severity of multiple sclerosis (MS) as an autoimmune and inflammatory disease. Our case-control study was performed on 84 patients with MS and 75 healthy subjects. The serum levels of IL-33, IL-37 and sVEGFR2 in the peripheral blood samples of all participants were measured by enzyme-linked immune sorbent assay (ELISA)...
August 2017: Iranian Journal of Allergy, Asthma, and Immunology
https://www.readbyqxmd.com/read/28857238/the-diversity-in-the-expression-profile-of-caveolin-ii-transcripts-considering-its-new-transcript-in-breast-cancer
#20
Mehdi Ariana, Nasibeh Arabi, Majid Pornour, Hajar Vaseghi, Shahla Mohammad Ganji, Mohammad Reza Alivand, Maryam Salari, Mohammad Esmaeil Akbari
Most studies have revealed the effects of caveolins in cancer inhibition. However, due to a lack of reports about their new transcripts, their presence and their effects on different cancers are unclear. This study was conducted to evaluate the cavolin-2 (cav-2) transcripts expression changes in tumoral and corresponding tissues and in contralateral breast, to investigate their variation associated with the variation of caveolin-1 (cav-1) expression in breast cancer. There were 40 breast-derived tumoral, corresponding, and contralateral tissues obtained from the patients with breast cancer...
February 2018: Journal of Cellular Biochemistry
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