keyword
https://read.qxmd.com/read/38493825/3d-printing-of-alginate-gelatin-scaffold-loading-tannic-acid-zif-8-for-wound-healing-in-vitro-and-in-vivo-studies
#1
JOURNAL ARTICLE
Mohammad Amin Fathollah Maghsoudi, Rouhollah Mehdinavaz Aghdam, Reza Akbari Asbagh, Ali Moghaddaszadeh, Azadeh Ghaee, Seyed Mohsen Ahmadi Tafti, Laleh Foroutani, Seyed Hossein Ahmadi Tafti
In the present study, ZIF-8 metal-organic framework (MOF) modified with Tannic acid (TA@ZIF-8) was synthesized and impregnated in alginate-gelatin (Alg-Gel) hydrogel. The Alg-Gel scaffolds containing 0, 5, and 10 % of TA@ZIF-8 were fabricated through the 3D printing method specifically denoted as Alg-Gel 0 %, Alg-Gel 5 %, and Alg-Gel 10 %. XRD, FTIR, FESEM, and EDX physically and chemically characterized the synthesized ZIF-8 and TA@ZIF-8 MOFs. Besides, Alg-Gel containing TA@ZIF-8 prepared scaffolds and their biological activity were also evaluated...
March 15, 2024: International Journal of Biological Macromolecules
https://read.qxmd.com/read/38481156/strabismus-management-in-retinoblastoma-survivors
#2
JOURNAL ARTICLE
Babak Masoomian, Carol L Shields, Hamid Riazi Esfahani, Atefeh Khalili, Fariba Ghassemi, Pukhraj Rishi, Mohammad Reza Akbari, Masoud Khorrami-Nejad
PURPOSE: To report the result of strabismus surgery in eye-salvaged retinoblastoma (Rb) patients. METHODS: A retrospective case series including 18 patients with Rb and strabismus who underwent strabismus surgery after completing tumor treatment by a single pediatric ophthalmologist. RESULTS: A total of 18 patients (10 females and 8 males) were included with a mean age of 13.3 ± 3.0 (range, 2-39) months at the time tumor presentation and 6...
March 13, 2024: BMC Ophthalmology
https://read.qxmd.com/read/38419894/improvement-of-5-fluorouracil-chemosensitivity-in-colorectal-cancer-cells-by-sirna-mediated-silencing-of-stat6-oncogene
#3
JOURNAL ARTICLE
Omid Rahbar Farzam, Behzad Baradaran, Bahman Akbari, Souzan Najafi, Mohammad Amini, AmirHossein Yari, Reza Dabbaghipour, Vahid Pourabdollah Kaleybar, Shiva Ahdi Khosroshahi
OBJECTIVES: Colorectal cancer (CRC) remains a major health concern worldwide due to its high incidence, mortality rate, and resistance to conventional treatments. The discovery of new targets for cancer therapy is essential to improve the survival of CRC patients. Here, this study aims to present a finding that identifies the STAT6 oncogene as a potent therapeutic target for CRC. MATERIALS AND METHODS: HT-29 CRC cells were transfected with STAT6 siRNA and treated with 5-fluorouracil (5-FU) alone and combined...
2024: Iranian Journal of Basic Medical Sciences
https://read.qxmd.com/read/38419602/burden-of-ischemic-heart-disease-in-the-middle-east-and-north-africa-mena-and-attributable-risk-factors-an-epidemiological-analysis-from-1990-to-2019
#4
JOURNAL ARTICLE
Mohammad Ahmadi, Shana Ahadi, Mohammad Amin Khadembashiri, Mohamad Mehdi Khadembashiri, Mehrdad Mahalleh, Hani AziziKia, Hamid Reza Zare, Amir Sobh Rakhshan Khah, Hamidreza Hekmat, Rajabali Daroudi, Ali Akbari Sari
INTRODUCTION: Despite the burden of ischemic heart disease (IHD), there remains a paucity of research on the incidence, mortality, and burden of this condition in the Middle East and North Africa (MENA) regions. This study aimed to evaluate the epidemiology and the risk factors associated with IHD in the MENA region. METHODS: This study was performed based on the GBD study 2019 data. We retrieved the data related to the epidemiology and burden of IHD, including prevalence, incidence, years of life lost due to premature death (YLLs), years lived with disability (YLDs), and mortality at the global level and in MENA countries across years and sexes...
February 2024: IJC Heart & Vasculature
https://read.qxmd.com/read/38394118/patterns-of-case-fatality-and-hospitalization-duration-among-nearly-1-million-hospitalized-covid-19-patients-covered-by-iran-health-insurance-organization-ihio-over-two-years-of-pandemic-an-analysis-of-associated-factors
#5
JOURNAL ARTICLE
Reza Mehrizi, Ali Golestani, Mohammad-Reza Malekpour, Hossein Karami, Mohammad Mahdi Nasehi, Mohammad Effatpanah, Mehdi Rezaee, Zahra Shahali, Ali Akbari Sari, Rajabali Daroudi
BACKGROUND: Different populations and areas of the world experienced diverse COVID-19 hospitalization and mortality rates. Claims data is a systematically recorded source of hospitalized patients' information that could be used to evaluate the disease management course and outcomes. We aimed to investigate the hospitalization and mortality patterns and associated factors in a huge sample of hospitalized patients. METHODS: In this retrospective registry-based study, we utilized claim data from the Iran Health Insurance Organization (IHIO) consisting of approximately one million hospitalized patients across various hospitals in Iran over a 26-month period...
2024: PloS One
https://read.qxmd.com/read/38384564/diatom-guided-bone-healing-via-a-hybrid-natural-scaffold
#6
JOURNAL ARTICLE
Mina Mohammadi, Samin Abbaszadeh, Vahideh Nosrati-Siahmazgi, Mahsa Akbari, Saman Rezaei, Kiyan Musaie, Mohammad Reza Eskandari, Hélder A Santos, Narges Poursina, Mohammad-Ali Shahbazi
Bone tissue engineering (BTE) involves the design of three-dimensional (3D) scaffolds that aim to address current challenges of bone defect healing, such as limited donor availability, disease transmission risks, and the necessity for multiple invasive surgeries. Scaffolds can mimic natural bone structure to accelerate the mechanisms involved in the healing process. Herein, a crosslinked combination of biopolymers, including gelatin (GEL), chitosan (CS), and hyaluronic acid (HA), loaded with diatom (Di) and β-sitosterol (BS), is used to produce GCH-Di-S scaffold by freeze-drying method...
February 29, 2024: Heliyon
https://read.qxmd.com/read/38379979/investigation-the-effect-of-dissimilar-laser-welding-parameters-on-temperature-field-mechanical-properties-and-fusion-zone-microstructure-of-inconel-600-and-duplex-2205-stainless-steel-via-response-surface-methodology
#7
JOURNAL ARTICLE
Ahmad Soleimani, Mohammad Akbari, Arash Karimipour, Amir Homayoon Meghdadi Isfahani, Reza Nosouhi
This study focused on dissimilar welding characterization of Inconel 600 and duplex 2205 stainless steel using central composite design (CCD) of experiments the response surface methodology (RSM). This study determined the effect of laser welding parameters and the reactions of the temperature field on the melt pool, the mechanical characteristics of the weld joint, and the geometry of the melt pool. According to the ANOVA results, the power of laser and focal distance were found to be the most influential factors on the temperature of both Inconel 600 and duplex stainless steel...
February 29, 2024: Heliyon
https://read.qxmd.com/read/38376804/-68-ga-ga-fap-2286-a-novel-promising-theragnostic-approach-for-pet-ct-imaging-in-patients-with-various-type-of-metastatic-cancers
#8
JOURNAL ARTICLE
Seyedeh Somayyeh Banihashemian, Ghasemali Divband, Elahe Pirayesh, Babak Nikkholgh, Hamidreza Amini, Abdolghafar Abolhosseini Shahrnoy, Reza Nami, Mohammad Esmaeil Akbari
BACKGROUND: Fibroblast activation protein (FAP) has emerged as a promising target for diagnosis and therapeutic intervention due to high expression and accumulation in the stromal compartments of a variety of malignant tumors. FAP-2286 utilizes cyclic peptides with FAP-binding characteristics to enhance the retention of the imaging agent within tumors, in contrast to the small-molecule FAP inhibitors (FAPI) like FAPI-04/46. The aim of this study was to quantify the tumor uptake of [68 Ga] Gallium-FAP-2286 within primary solid tumors, adjacent excised tissues, and metastatic lesions...
February 20, 2024: European Journal of Nuclear Medicine and Molecular Imaging
https://read.qxmd.com/read/38269632/effects-of-flaxseed-supplementation-on-weight-loss-lipid-profiles-glucose-and-high-sensitivity-c-reactive-protein-in-patients-with-coronary-artery-disease-a-systematic-review-and-meta-analysis-of-randomized-controlled-trials
#9
REVIEW
Hamid Reza Sabet, Mohammad Ahmadi, Mehdi Akrami, Mahsa Motamed, Omid Keshavarzian, Mozhan Abdollahi, Mehdi Rezaei, Hamed Akbari
This meta-analysis aimed to evaluate the effects of flaxseed supplementation on weight loss, lipid profiles, high-sensitivity C-reactive protein (hs-CRP), and glucose levels in patients with coronary artery disease (CAD). A systematic search was performed using various online databases, including Scopus, PubMed, Web of Science, EMBASE, and Cochrane Library, to identify relevant randomized controlled trials (RCTs) until June 2023. To evaluate heterogeneity among the selected studies, the Q-test and I2 statistics were employed...
January 2024: Clinical Cardiology
https://read.qxmd.com/read/38267968/sexual-function-index-adaptation-for-breast-cancer-patients-fsfi-bc-translation-and-psychometric-properties-of-persian-version
#10
JOURNAL ARTICLE
Marzieh Masjoudi, Zohre Keshavarz, Mohammad Esmaeil Akbari, Farah Lotfi Kashani, Malihe Nasiri, Hamid-Reza Mirzaei
BACKGROUND: Effective interventions to improve sexual dysfunction in breast cancer survivors need screening of these dysfunctions with a suitable instrument. The aim of present study was translation and identifying psychometric properties of Female Sexual Function Index - Adapted for Breast Cancer (FSFI-BC) which has been specifically developed for breast cancer survivors. METHOD: This methodological study was performed between February 2017 and October 2018. 200 breast cancer survivors in stage 1 or 2 who were selected through convenience sampling method, completed the questionnaire...
January 24, 2024: BMC Women's Health
https://read.qxmd.com/read/38228040/breast-cancer-incidence-trends-in-golestan-iran-an-age-period-cohort-analysis-by-ethnic-region-2004-2018
#11
JOURNAL ARTICLE
Fatemeh Ghasemi-Kebria, Abdolreza Fazel, Shahryar Semnani, Arash Etemadi, Mohammad Naeimi-Tabiei, Susan Hasanpour-Heidari, Faezeh Salamat, Nastaran Jafari-Delouie, SeyedMehdi Sedaghat, Hamideh Sadeghzadeh, Mahnaz Akbari, Mahshid Mehrjerdian, Elisabete Weiderpass, Gholamreza Roshandel, Freddie Bray, Reza Malekzadeh
BACKGROUND: We aimed to examine the effects of age, diagnosis year (calendar period) and birth year (cohort) on the incidence trends of breast cancer among Golestan women, Northeast Iran, 2004-2018. METHODS: Incidence data were obtained by residential status (urban/rural) and ethnic region (Turkmens/non-Turkmens). We calculated age-standardized incidence rates (ASRs) per 100,000 person-years. The estimated annual percentage change (EAPC) were calculated, and age-period-cohort (APC) models fitted to assess non-linear effects of period and cohort as incidence rate ratios (IRRs)...
January 15, 2024: Cancer Epidemiology
https://read.qxmd.com/read/38218307/the-effect-of-resistance-exercises-using-an-elastic-band-on-balance-and-fear-of-falling-in-older-adults-with-diabetic-peripheral-neuropathy-a-16-week-randomized-controlled-trial
#12
JOURNAL ARTICLE
Mohammad Reza Armat, Hamed Mortazavi, Hadi Akbari, Saeedeh Baghizade
OBJECTIVE: The current study aimed to investigate the effect of resistance training using an elastic band on balance and fear of falling in older adults with diabetic peripheral neuropathy. DESIGN: The study was a clinical controlled trial with a repeated measure design SETTING: Iranian Diabetes Foundation of Mashhad PARTICIPANTS: The participants were 51 older adults with diabetic peripheral neuropathy and balance impairment. INTERVENTIONS: Participants were randomly assigned to two groups; one group received balance training using an elastic band and the other group just received balance training...
January 11, 2024: Archives of Physical Medicine and Rehabilitation
https://read.qxmd.com/read/38215611/refractive-features-and-amblyopia-in-duane-s-retraction-syndrome-a-review-of-the-582-patients
#13
JOURNAL ARTICLE
Masoud Khorrami-Nejad, Mohammad Reza Akbari, Motahhareh Sadeghi, Babak Masoomian, Arash Mirmohammadsadeghi, Mohammed Khalaf Mohsin, Noor Hamad
PURPOSE: To report the visual and refractive characteristics and the prevalence of amblyopia in patients with different types of Duane's Retraction Syndrome (DRS). METHOD: This retrospective study was performed on hospital records of 582 DRS patients at Farabi Hospital, Iran, from 2012 to March 2022. RESULTS: The mean age of patients was 19.4 ± 11.9 (range, 3-70) years [335 (57.6 %) females and 247 (42.4 %) males (P < ...
January 11, 2024: Journal of Optometry
https://read.qxmd.com/read/38193167/evaluation-of-physicochemical-textural-and-microbial-characteristics-of-probiotic-soy-cheese-during-storage-generation-and-isolation-of-bioactive-peptides
#14
JOURNAL ARTICLE
Somayeh Mashayekh, Rezvan Pourahmad, Behrouz Akbari-Adergani, Mohammad Reza Eshaghi
The purpose of this study was to ascertain how probiotic culture affected the physicochemical, textural, and microbiological characteristics of probiotic soy cheese during storage. Moreover, the release of bioactive peptides during fermentation and storage was examined. Each cheese sample was made from one of the probiotic cultures of Lactobacillus acidophilus , Lacticaseibacillus casei , and Bifidobacterium lactis . Peptide extracts were prepared from these samples and fractionated using reversed-phase high-performance liquid chromatography...
January 9, 2024: Food Science and Technology International
https://read.qxmd.com/read/38185635/interplay-of-mirnas-and-lncrnas-in-stat3-signaling-pathway-in-colorectal-cancer-progression
#15
REVIEW
Omid Rahbar Farzam, Souzan Najafi, Mohammad Amini, Zohreh Rahimi, Reza Dabbaghipour, Omid Zohdi, Ghazale Asemani Shahgoli, Behzad Baradaran, Bahman Akbari
In recent decades, colorectal cancer (CRC) has turned into one of the most widespread malignancies, and the incidence of this malignancy is expected to increase. Despite considerable improvements in therapeutic approaches, the prognosis, and the management of CRC face many problems. Likely, the main limitation in the successful treatment of CRC is the lack of appropriate clinical therapeutic targets. As an effective target, the signal transducer and activator of transcription 3 (STAT3) are regulated by a wide range of genes and involved in cellular processes, including cell growth, migration, invasion, immunosuppression, and angiogenesis...
January 7, 2024: Cancer Cell International
https://read.qxmd.com/read/38178058/dental-service-utilization-and-the-covid-19-pandemic-a-micro-data-analysis
#16
JOURNAL ARTICLE
Amir Akbari, Mohammad Reza Khami, Amine Beymouri, Solmaz Akbari
BACKGROUND: Global crises and disease pandemics, such as COVID-19, negatively affect dental care utilization by several factors, such as infection anxiety, disrupted supply chains, economic contraction, and household income reduction. Exploring the pattern of this effect can help policy makers to be prepared for future crises. The present study aimed to investigate the financial impact of COVID-19 disruptions on dental service utilization. METHODS: Data on the number of dental services offered in Dental School Clinics of Tehran University of Medical Sciences was collected over a period of two years, before and after the initial COVID-19 outbreak in Iran...
January 4, 2024: BMC Oral Health
https://read.qxmd.com/read/38173472/evaluation-the-cytotoxic-effect-of-fe-3-o-4-glu-gingerol-on-lung-adenocarcinoma-cell-line-a549-with-biological-mechanisms
#17
JOURNAL ARTICLE
Tabarek Abdulrazaq Alkinani, Fahimeh Abedini Bajgiran, Mohammad Rezaei, Ali Motamedi Maivan, Fatemeh Jafari Golrokh, Mona Bejarbaneh, Sara Rezaei Mojdehi, Sahar Gorji, Reza Ghasemian, Mohammad Dashtban Jalil Pustin Sarai, Fatemeh Akbari, Somayeh Dehghan, Fatemeh Mirzaee, Noor Hussein Abdulrahman, Ali Salehzadeh
The use of nanotechnology products with supermagnetic properties for targeted delivery of drugs has gained attention recently. Due to the anticancer features of Gingerol, the major phenolic compound from Ginger, this study aims to prepare Fe3 O4 @Glucose-Gingerol nanoparticles (NPs) and investigate their anticancer potential in a lung adenocarcinoma cell line. The physical and chemical features of the nanoparticles were investigated by FT-IR, XRD, zeta potential, DLS, EDS mapping, VSM, and electron microscope imaging...
January 15, 2024: Heliyon
https://read.qxmd.com/read/38129729/a-decision-support-framework-to-evaluate-the-sustainability-performance-of-urban-road-transportation
#18
JOURNAL ARTICLE
Ardavan Babaei, Majid Khedmati, Mohammad Reza Akbari Jokar, Erfan Babaee Tirkolaee
This study proposes a decision support framework (DSF) based on two data envelopment analysis (DEA) models in order to evaluate the urban road transportation of countries for sustainable performance management during different years. The first model considers different years independently while the second model, which is a type of network model, takes into account all the years integrated. A multi-objective programming model under two types of uncertainties is then developed to solve the proposed DEA models based on a revised multi-choice goal programming (GP) approach...
December 22, 2023: Environmental Science and Pollution Research International
https://read.qxmd.com/read/38124008/recontact-to-return-new-or-updated-palb2-genetic-results-in-the-clinical-laboratory-setting
#19
JOURNAL ARTICLE
Seema Panchal, Radhika Mahajan, Navneet Aujla, Paul McKay, Selina Casalino, Vanessa Di Gioacchino, George S Charames, Maude Lefebvre, Kelly A Metcalfe, Mohammad Reza Akbari, Jeanna Marie McCuaig, Jordan Lerner-Ellis
OBJECTIVE: The purpose of this study was to recontact individuals with clinically actionable test results identified through a retrospective research study and to provide a framework for laboratories to recontact patients. METHODS: Genetic testing was conducted on 2977 individuals originally referred for BRCA1 and BRCA2 hereditary breast and ovarian cancer testing that had a negative genetic test result. A gene panel was used to identify pathogenic variants in known or newly discovered genes that could explain the underlying cause of disease; however, analysis was restricted to PALB2 for the purposes of this study...
December 19, 2023: Journal of Medical Genetics
https://read.qxmd.com/read/38028040/nonoperative-management-of-biliopleural-fistula-following-living-donor-liver-transplantation-a-case-report
#20
Kourosh Kazemi, Alireza Rasekhi, Sahar Sohrabi Nazari, Mohammad Mehdi Lashkarizadeh, Alireza Shamsaeefar, Mohammad Alikhani, Ali Akbari, Reza Shahriarirad
KEY CLINICAL MESSAGE: Biliopleural fistula is a rare but serious complication after liver transplantation that should be managed nonoperatively with antibiotics, pleural drainage, decompression of high-pressure biliary tract, or ultimately surgery in unresponsive cases. ABSTRACT: Bilious pleural effusion is a rare entity often iatrogenic, following hepatobiliary surgeries and biliary interventions, and has been reported only in a limited number of patients after liver transplantation...
November 2023: Clinical Case Reports
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