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Opioids, cachexia, delirium, terminal care, palliative care, pain

E Bruera, C M Neumann
During the past 10 years there have been major changes in the management of the most common symptoms of terminal cancer. Opioid agonists remain the mainstay in the management of cancer pain. Slow-release preparations are currently available for several of these agents. The increased use of opioids has led to the recognition of opioid-induced neurotoxic effects and to the development of effective adjuvant drugs and other strategies to counteract these side effects. A number of drugs are available for the management of symptoms of cachexia, including corticosteroids and progestational drugs...
June 30, 1998: CMAJ: Canadian Medical Association Journal, Journal de L'Association Medicale Canadienne
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