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https://www.readbyqxmd.com/read/27903795/how-can-professionals-carry-out-recognition-towards-children-of-parents-with-alcohol-problems-a-qualitative-interview-study
#1
Anne Werner, Kirsti Malterud
AIM: The aim of this study was to explore informal adult support experienced by children with parental alcohol problems to understand how professionals can show recognition in a similar way. METHODS: We conducted a qualitative interview study with retrospective accounts from nine adults growing up with problem-drinking parents. Data were analysed with systematic text condensation. Goffman's concept "frame" offered a lens to study how supportive situations were defined and to understand opportunities and limitations for translation of recognition acts and attitudes to professional contexts...
November 30, 2016: Scandinavian Journal of Public Health
https://www.readbyqxmd.com/read/27903364/-a-meta-analysis-of-hiv-seroprevalence-in-pregnant-women-with-syphilis-and-the-impact-of-syphilis-infection-on-mother-to-child-hiv-transmission
#2
T T Wang, Y Xu, Z Z Li, L Z Chen
Objective: To estimate HIV seroprevalence among pregnant women with syphilis and evaluate the influence of syphilis infection on mother-to-child-transmission (MTCT) of HIV by meta-analysis. Methods: We conducted a systematic literature search for 1 678 articles related to maternal syphilis and HIV infection published until October 1(st) 2015 using the PubMed, Web of Science, Chinese Web of Knowledge, Wanfang, Weipu, and SinoMed databases and evaluated the quality of each papers using the STROBE checklist, and the keywords were " pregnant women/maternal/pregnancy" , "syphilis/AIDS" , "HIV/human immunodeficiency virus" , "mother- to-child transimission/vertical transmission" ...
November 6, 2016: Zhonghua Yu Fang Yi Xue za Zhi [Chinese Journal of Preventive Medicine]
https://www.readbyqxmd.com/read/27902695/text-mining-genotype-phenotype-relationships-from-biomedical-literature-for-database-curation-and-precision-medicine
#3
Ayush Singhal, Michael Simmons, Zhiyong Lu
The practice of precision medicine will ultimately require databases of genes and mutations for healthcare providers to reference in order to understand the clinical implications of each patient's genetic makeup. Although the highest quality databases require manual curation, text mining tools can facilitate the curation process, increasing accuracy, coverage, and productivity. However, to date there are no available text mining tools that offer high-accuracy performance for extracting such triplets from biomedical literature...
November 2016: PLoS Computational Biology
https://www.readbyqxmd.com/read/27901326/tuberculuma-sellae-meningiomas-a-systematic-review-of-transcranial-approaches-in-the-endoscopic-era
#4
Mazda Turel, Georgios Tsermoulas, Abdulmounem Yasssin-Kassab, Deven Reddy, Hugo Andrade-Barazarte, Lior Gonen, Gelareh Zadeh, Fred Gentili
INTRODUCTION: With the advent of skull base endoscopy, tuberculum sellae meningiomas (TSMs) are currently operated both from the traditional transcranial (TC) route as well as the extended endonasal endoscopic trasnssphenoidal approach (EETS). The aim of this study was to conduct a systematic review of TSMs excised via the TC route in the modern era when the EETS excision is gaining popularity. EVIDENCE ACQUISITION: We performed a systematic review in the medical literature following the PRISMA guidelines...
November 30, 2016: Journal of Neurosurgical Sciences
https://www.readbyqxmd.com/read/27900159/can-t-play-won-t-play-longitudinal-changes-in-perceived-barriers-to-participation-in-sports-clubs-across-the-child-adolescent-transition
#5
Laura Basterfield, Lauren Gardner, Jessica K Reilly, Mark S Pearce, Kathryn N Parkinson, Ashley J Adamson, John J Reilly, Stewart A Vella
BACKGROUND: Participation in sports is associated with numerous physical and psychosocial health benefits, however, participation declines with age, and knowledge of perceived barriers to participation in children is lacking. This longitudinal study of children and adolescents aimed to use the ecological model of physical activity to assess changes in barriers to participation in sports clubs to identify age-specific and weight-specific targets for intervention. METHODS: Longitudinal study-Perceived barriers to sports participation were collected from a birth cohort, the Gateshead Millennium Study (n>500) at ages 9 and 12 years...
2016: BMJ Open Sport & Exercise Medicine
https://www.readbyqxmd.com/read/27899563/chimerdb-3-0-an-enhanced-database-for-fusion-genes-from-cancer-transcriptome-and-literature-data-mining
#6
Myunggyo Lee, Kyubum Lee, Namhee Yu, Insu Jang, Ikjung Choi, Pora Kim, Ye Eun Jang, Byounggun Kim, Sunkyu Kim, Byungwook Lee, Jaewoo Kang, Sanghyuk Lee
Fusion gene is an important class of therapeutic targets and prognostic markers in cancer. ChimerDB is a comprehensive database of fusion genes encompassing analysis of deep sequencing data and manual curations. In this update, the database coverage was enhanced considerably by adding two new modules of The Cancer Genome Atlas (TCGA) RNA-Seq analysis and PubMed abstract mining. ChimerDB 3.0 is composed of three modules of ChimerKB, ChimerPub and ChimerSeq. ChimerKB represents a knowledgebase including 1066 fusion genes with manual curation that were compiled from public resources of fusion genes with experimental evidences...
November 28, 2016: Nucleic Acids Research
https://www.readbyqxmd.com/read/27899397/chronic-obstructive-pulmonary-disease-and-the-risk-of-stroke-a-systematic-review-protocol
#7
Ann D Morgan, Chetna Sharma, Kieran J Rothnie, Jennifer K Quint
INTRODUCTION: There is good evidence to suggest that chronic obstructive pulmonary disease (COPD) increases the risk of ischaemic heart disease, in particular myocardial infarction (MI). The relationship between stroke and COPD, however, is not as well established, and studies conducted to date have generated conflicting results. METHODS AND ANALYSIS: MEDLINE and Embase will be searched for relevant articles using a prespecified search strategy. We will target observational studies conducted in the general population that employ either a longitudinal cohort or case-control study design to estimate ORs, HRs or incident rate ratios for the association between COPD and a subsequent first stroke...
November 29, 2016: BMJ Open
https://www.readbyqxmd.com/read/27899279/wormbase-parasite-a-comprehensive-resource-for-helminth-genomics
#8
Kevin L Howe, Bruce J Bolt, Myriam Shafie, Paul Kersey, Matthew Berriman
The number of publicly available parasitic worm genome sequences has increased dramatically in the past three years, and research interest in helminth functional genomics is now quickly gathering pace in response to the foundation that has been laid by these collective efforts. A systematic approach to the organisation, curation, analysis and presentation of these data is clearly vital for maximising the utility of these data to researchers. We have developed a portal called WormBase ParaSite (http://parasite...
November 26, 2016: Molecular and Biochemical Parasitology
https://www.readbyqxmd.com/read/27899033/novel-antibacterial-polymeric-nanocomposite-for-smart-co-delivery-of-anticancer-drugs
#9
Elham Zakerzadeh, Effat Alizadeh, Hossein Samadi Kafil, Azad Mohammad Hassanzadeh, Roya Salehi, Mehrdad Mahkam
Here a novel antibacterial nanocomposite was developed for combination cancer therapy. The synthesized nanocarrier was characterized by FTIR, (1)H NMR, thermogravimetric analysis (TGA), and FESEM-EDX. Its antibacterial activity was assessed by determining minimum inhibitory concentration (MIC) values. Doxorubicin (DOX) and methotrexate (MTX) conjugation with nanocarrier sustained the release of both drugs with apparent pH-triggered manner. Co-administration of DOX with MTX leads to an efficient anticancer performance to MCF7 cell lines verified by qRT-PCR and MTT assay tests...
November 29, 2016: Artificial Cells, Nanomedicine, and Biotechnology
https://www.readbyqxmd.com/read/27897139/influence-of-electromechanical-coupling-on-optical-properties-of-ingan-quantum-dot-based-light-emitting-diodes
#10
Daniele Barettin, Matthias Auf der Maur, Aldo di Carlo, Alessandro Pecchia, Andrei F Tsatsulnikov, Alexei V Sakharov, Wsevolod V Lundin, Andrei E Nikolaev, Sergey O Usov, Nikolay Cherkashin, Martin J Hÿtch, Sergey Yu Karpov
The impact of electromechanical coupling on optical properties of light-emitting diodes (LEDs) with InGaN/GaN quantum-dot (QD) active regions is studied by numerical simulations. The structure, i.e. the shape and the average In content of the QDs, has been directly derived from experimental data on out-of-plane strain distribution obtained from the geometric-phase analysis of a high-resolution transmission electron microscopy image of an LED structure grown by metalorganic vapor-phase epitaxy. Using continuum [Formula: see text] calculations, we have studied first the lateral and full electromechanical coupling between the QDs in the active region and its impact on the emission spectrum of a single QD located in the center of the region...
November 29, 2016: Nanotechnology
https://www.readbyqxmd.com/read/27895101/interaction-and-common-ground-in-dementia-communication-across-linguistic-and-cultural-diversity-in-a-residential-dementia-care-setting
#11
Lisa Strandroos, Eleonor Antelius
Previous research concerning bilingual people with a dementia disease has mainly focused on the importance of sharing a spoken language with caregivers. While acknowledging this, this article addresses the multidimensional character of communication and interaction. As using spoken language is made difficult as a consequence of the dementia disease, this multidimensionality becomes particularly important. The article is based on a qualitative analysis of ethnographic fieldwork at a dementia care facility. It presents ethnographic examples of different communicative forms, with particular focus on bilingual interactions...
November 28, 2016: Health (London)
https://www.readbyqxmd.com/read/27894686/the-use-of-the-lymphocyte-cytokinesis-block-micronucleus-assay-for-monitoring-pesticide-exposed-populations
#12
REVIEW
Claudia Bolognesi, Nina Holland
Pesticides are widely used around the world, and hundreds of millions of people are exposed annually in occupational and environmental settings. Numerous studies have demonstrated relationships between pesticide exposure and increased risk of cancers, neurodegenerative and neurodevelopmental disorders, respiratory diseases and diabetes. Assessment of genotoxicity of pesticides and biomonitoring their effect in exposed populations is critical for a better regulation and protection, but it can be complicated because pesticides are often used as complex mixtures...
October 2016: Mutation Research
https://www.readbyqxmd.com/read/27894456/a-systematic-review-and-meta-analysis-of-the-effort-reward-imbalance-model-of-workplace-stress-with-indicators-of-immune-function
#13
REVIEW
Pennie Eddy, Rachael Heckenberg, Eleanor H Wertheim, Stephen Kent, Bradley J Wright
OBJECTIVE: Despite considerable research into associations between the effort reward imbalance (ERI) model and various health outcomes over the past 20years, the underlying mechanisms responsible for the association remain unclear. Recently, ERI investigations have examined associations with immune sub-systems (e.g., leukocytes, cytokines and immunoglobulins). Synthesis of the amalgamated research evidence will aid clarity to this field of enquiry. We conducted a meta-analysis and reviewed the associations of ERI and over-commitment (OC) in the workplace with immunity...
December 2016: Journal of Psychosomatic Research
https://www.readbyqxmd.com/read/27893870/associations-between-hydration-status-intravenous-fluid-administration-and-outcomes-of-patients-infected-with-shiga-toxin-producing-escherichia-coli-a-systematic-review-and-meta-analysis
#14
Silviu Grisaru, Jianling Xie, Susan Samuel, Lisa Hartling, Phillip I Tarr, David Schnadower, Stephen B Freedman
Importance: The associations between hydration status, intravenous fluid administration, and outcomes of patients infected with Shiga toxin-producing Escherichia coli (STEC) remain unclear. Objective: To determine the relationship between hydration status, the development and severity of hemolytic uremic syndrome (HUS), and adverse outcomes in STEC-infected individuals. Data Sources: MEDLINE, EMBASE, Cochrane Central Register of Controlled Trials via the OvidSP platform, PubMed via the National Library of Medicine, CINAHL Plus with full text, Scopus, Web of Science, ClinicalTrials...
November 28, 2016: JAMA Pediatrics
https://www.readbyqxmd.com/read/27893648/quantity-and-quality-of-economic-evaluations-in-u-s-nursing-research-1997-2015-a-systematic-review
#15
Wendy A Cook, Megan L Morrison, Linda H Eaton, Brian R Theodore, Ardith Z Doorenbos
BACKGROUND: The United States has a complex healthcare system that is undergoing substantial reformations. There is a need for high-quality, economic evaluations of nursing practice. An updated review of completed economic evaluations relevant to the field of nursing within the U.S. healthcare system is timely and needed. OBJECTIVES: The purpose of this study was to evaluate and describe the quantity and quality of economic evaluations in nursing-relevant research performed in the United States between 1997 and 2015...
November 23, 2016: Nursing Research
https://www.readbyqxmd.com/read/27893267/identity-adjustment-among-afghanistan-and-iraq-war-veterans-with-reintegration-difficulty
#16
Robert J Orazem, Patricia A Frazier, Paula P Schnurr, Heather E Oleson, Kathleen F Carlson, Brett T Litz, Nina A Sayer
Objective: To examine perceptions of identity adjustment in a diverse, national sample of U.S. veterans of the wars in Afghanistan and Iraq. Method: The authors conducted a planned thematic analysis of text written by Afghanistan and Iraq war veterans when they were asked to describe their reintegration difficulties as part of a randomized controlled trial (RCT) of online expressive writing (Sayer et al., 2015). Participants were 100 randomly selected veterans from the larger study (42 women and 58 men, 60 active duty and 38 reserves or National Guard)...
November 28, 2016: Psychological Trauma: Theory, Research, Practice and Policy
https://www.readbyqxmd.com/read/27893256/sticks-and-stones-can-break-my-bones-but-words-can-also-hurt-me-the-relationship-between-customer-verbal-aggression-and-employee-incivility
#17
David D Walker, Danielle D van Jaarsveld, Daniel P Skarlicki
Customer service employees tend to react negatively to customer incivility by demonstrating incivility in return, thereby likely reducing customer service quality. Research, however, has yet to uncover precisely what customers do that results in employee incivility. Through transcript and computerized text analysis in a multilevel, multisource, mixed-method field study of customer service events (N = 434 events), we found that employee incivility can occur as a function of customer (a) aggressive words, (b) second-person pronoun use (e...
November 28, 2016: Journal of Applied Psychology
https://www.readbyqxmd.com/read/27893026/prevalence-of-depression-in-patients-with-mild-cognitive-impairment-a-systematic-review-and-meta-analysis
#18
Zahinoor Ismail, Heba Elbayoumi, Corinne E Fischer, David B Hogan, Colleen P Millikin, Tom Schweizer, Moyra E Mortby, Eric E Smith, Scott B Patten, Kirsten M Fiest
Importance: Depression is common in individuals with mild cognitive impairment (MCI) and may confer a higher likelihood of progression to dementia. Prevalence estimates of depression in those with MCI are required to guide both clinical decisions and public health policy, but published results are variable and lack precision. Objective: To provide a precise estimate of the prevalence of depression in individuals with MCI and identify reasons for heterogeneity in the reported results...
November 23, 2016: JAMA Psychiatry
https://www.readbyqxmd.com/read/27892822/the-effect-of-manipulated-information-about-premenstrual-changes-on-the-report-of-positive-and-negative-premenstrual-changes
#19
Johanna N Kues, Carolyn Janda, Clara Krzikalla, Gerhard Andersson, Cornelia Weise
Although women predominantly report negative premenstrual changes, a substantial portion of women also reports positive changes. Little is known about factors related to report of positive and negative premenstrual changes. The aim of this experimental study at the [deleted for blind review process] from January and February 2015 was to investigate the effect of manipulated information about premenstrual changes on the retrospective report of premenstrual changes. A total of 241 healthy women were randomly assigned either to a experimental group (EG) reading: (1) text focusing on negative and positive premenstrual changes (EG1 (±)), (2) text focusing on negative changes (EG2 (-)), or (3) control group (CG) text...
November 28, 2016: Women & Health
https://www.readbyqxmd.com/read/27891235/interaction-and-medical-inducement-between-pharmaceutical-representatives-and-physicians-a-meta-synthesis
#20
REVIEW
Shahrzad Salmasi, Long Chiau Ming, Tahir Mehmood Khan
BACKGROUND: It has been proven that the interaction between pharmaceutical representatives and physicians can directly influence the latter's prescribing behaviour. This meta-synthesis aims to explore the available studies regarding the nature of the interaction that takes place between pharmaceutical representatives and physicians. It highlights the different aspects of that interaction by investigating the reasons why these meetings happen in the first place, their benefits and drawbacks and their impact on patients' health and, ultimately, the health of the public...
2016: Journal of Pharmaceutical Policy and Practice
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