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https://www.readbyqxmd.com/read/28358745/stenotrophomonas-maltophilia-endophthalmitis-1-month-after-intravitreal-aflibercept
#1
Paul S Boeke, Justin L Gottlieb
PURPOSE: Endophthalmitis caused by Stenotrophomonas maltophilia is rare and has been described after cataract surgery and open globe injuries. We report a patient with endophthalmitis caused by this organism after uncomplicated intravitreal aflibercept injection. METHODS: A 70-year-old man with a history of anti-vascular endothelial growth factor therapy for diabetic macular edema presented 23 days after aflibercept injection with clinical diagnosis of endophthalmitis...
March 29, 2017: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/28190731/early-binocular-input-is-critical-for-development-of-audiovisual-but-not-visuotactile-simultaneity-perception
#2
Yi-Chuan Chen, Terri L Lewis, David I Shore, Daphne Maurer
Temporal simultaneity provides an essential cue for integrating multisensory signals into a unified perception. Early visual deprivation, in both animals and humans, leads to abnormal neural responses to audiovisual signals in subcortical and cortical areas [1-5]. Behavioral deficits in integrating complex audiovisual stimuli in humans are also observed [6, 7]. It remains unclear whether early visual deprivation affects visuotactile perception similarly to audiovisual perception and whether the consequences for either pairing differ after monocular versus binocular deprivation [8-11]...
February 20, 2017: Current Biology: CB
https://www.readbyqxmd.com/read/28181225/electrophysiological-evidence-of-altered-visual-processing-in-adults-who-experienced-visual-deprivation-during-infancy
#3
Sidney J Segalowitz, Avital Sternin, Terri L Lewis, Jane Dywan, Daphne Maurer
We examined the role of early visual input in visual system development by testing adults who had been born with dense bilateral cataracts that blocked all patterned visual input during infancy until the cataractous lenses were removed surgically and the eyes fitted with compensatory contact lenses. Patients viewed checkerboards and textures to explore early processing regions (V1, V2), Glass patterns to examine global form processing (V4), and moving stimuli to explore global motion processing (V5). Patients' ERPs differed from those of controls in that (1) the V1 component was much smaller for all but the simplest stimuli and (2) extrastriate components did not differentiate amongst texture stimuli, Glass patterns, or motion stimuli...
February 9, 2017: Developmental Psychobiology
https://www.readbyqxmd.com/read/28168827/auckland-cataract-study-2-clinical-outcomes-of-phacoemulsification-cataract-surgery-in-a-public-teaching-hospital
#4
Bia Z Kim, Dipika V Patel, Charles Nj McGhee
IMPORTANCE: A contemporary benchmark for the most common ophthalmic surgery. BACKGROUND: To assess patient characteristics and outcomes of contemporary phacoemulsification cataract surgery in a New Zealand public teaching hospital setting. DESIGN: Prospective observational study. PARTICIPANTS: Consecutive cases (N = 500) of phacoemulsification surgery between April and June 2015. METHODS: An independent observer assessed all clinical and surgical data pre-operatively and 4-6 weeks post-operatively...
February 7, 2017: Clinical & Experimental Ophthalmology
https://www.readbyqxmd.com/read/28121209/combined-treatment-with-intravitreal-bevacizumab-and-laser-photocoagulation-for-exudative-maculopathy-in-facioscapulohumeral-muscular-dystrophy
#5
Rita Matos, João Beato, Marta Silva, Sérgio Silva, Elisete Brandão, Fernando Falcão-Reis, Susana Penas
PURPOSE: To report a rare case of exudative maculopathy in a patient with facioscapulohumeral muscular dystrophy (FSHD), and its management. METHODS: Observational case report. RESULTS: A 62-year-old man with genetically confirmed FSHD was referred to our department complaining of decreased visual acuity in his left eye. At presentation, right eye examination was unremarkable and best-corrected visual acuity (BCVA) was 20/20. Left eye BCVA was 20/100 and it presented a dense cataract with the evidence of macular lipid exudation...
January 25, 2017: Ophthalmic Genetics
https://www.readbyqxmd.com/read/27956288/primary-posterior-capsulotomy-in-adults-with-posterior-capsule-opacification
#6
Haitham Younis Al-Nashar, Ahmad Saeed Khalil
PURPOSE: To evaluate the efficacy and safety of primary posterior continuous curvilinear capsulorhexis (PCCC) in adult patients with cataract. SETTING: Zagazig University Hospital, Ash-Sharkya, Egypt. DESIGN: Prospective nonrandomized case series. METHODS: This study comprised patients with senile cataract who had phacoemulsification. All patients had a dense posterior capsule opacification (PCO) discovered intraoperatively...
November 2016: Journal of Cataract and Refractive Surgery
https://www.readbyqxmd.com/read/27801692/histopathology-of-subcapsular-cataract-in-a-patient-with-atopic-dermatitis
#7
Daisy Yao Shu, Keith Ong, Frank J Lovicu
PURPOSE: To report the histopathological features of anterior subcapsular cataract associated with atopic dermatitis. CASE REPORT: A 29-year-old man with atopic dermatitis presented with bilateral anterior subcapsular cataract. After routine cataract surgery, the anterior subcapsular cataractous tissue was obtained as an anterior capsulorhexis flap and prepared as a wholemount for histological analysis. The wholemount consisted of a well-demarcated central grayish-white plaque surrounded by transparent capsule, corroborating the slit-lamp biomicroscopic appearance...
February 2017: Optometry and Vision Science: Official Publication of the American Academy of Optometry
https://www.readbyqxmd.com/read/27783092/development-of-monofixation-syndrome-after-extraction-of-dense-cataracts
#8
RANDOMIZED CONTROLLED TRIAL
H Sprague Eustis, Adam Janot, Chirag Jhaveri
PURPOSE: If the interruption of macular fusion for an extended period of time is the key event that results in the development of monofixation syndrome, then the decreased macular input caused by dense cataracts may cause monofixation syndrome in adults. This study was designed to test this hypothesis. METHODS: The study design was a retrospective chart review that identified patients with unilateral cataracts at two southern Louisiana medical centers. Patients were assigned to the dense cataract group if a unilateral cataract had been present for at least 3 months and led to a visual acuity of worse than 20/200...
January 1, 2017: Journal of Pediatric Ophthalmology and Strabismus
https://www.readbyqxmd.com/read/27746025/persisting-cross-modal-changes-in-sight-recovery-individuals-modulate-visual-perception
#9
Maria J S Guerreiro, Lisa Putzar, Brigitte Röder
Recent neuroimaging studies have demonstrated that a brief period of congenital blindness induces long-lasting reorganization within the visual cortex of sight-recovery humans [1, 2]. However, the behavioral consequences of this cross-modal reorganization are not yet known. Here we investigated this question by examining the transfer of motion aftereffects across the visual and auditory modalities within six individuals who had been born blind due to dense bilateral cataracts and regained sight when they were treated at 5-24 months of age...
November 21, 2016: Current Biology: CB
https://www.readbyqxmd.com/read/27631481/intraoperative-optical-coherence-tomography-imaging-and-assessment-of-the-macula-during-cataract-surgery-a-novel-technique
#10
Koushik Tripathy, Rohan Chawla, Babulal Kumawat, Yog Raj Sharma
The authors describe a technique to qualitatively analyze the posterior segment during cataract surgery using intraoperative optical coherence tomography (iOCT). Macular iOCT can be done before and after intraocular lens implantation after the media is rendered clear following phacoemulsification. A handheld irrigating planoconcave contact lens is placed over the cornea with the operating microscope in retroillumination mode. After focusing the microscope and upon getting a clear view of the posterior segment, iOCT is switched on, centered at the macula, and focused...
September 1, 2016: Ophthalmic Surgery, Lasers & Imaging Retina
https://www.readbyqxmd.com/read/27626152/microscopic-analysis-of-an-opacified-oft-cryl%C3%A2-hydrophilic-acrylic-intraocular-lens
#11
Bruna Vieira Ventura, Kyle Douglas MacLean, Wagner Lira, Daniele Mendes de Oliveira, Camila Vieira Ventura, Liliana Werner
A 51-year-old patient underwent posterior vitrectomy with perfluoropropane gas injection, phacoemulsification, and implantation of an Oft Cryl® hydrophilic acrylic intraocular lens (IOL) because of traumatic retinal detachment and cataract in the right eye. On the first postoperative day, gas was filling the anterior chamber because of patient's non-compliance in terms of head positioning, and was reabsorbed within one week. Eight months later, the patient returned complaining of a significant decrease in vision...
July 2016: Arquivos Brasileiros de Oftalmologia
https://www.readbyqxmd.com/read/27622189/lens-density-measurements-by-two-independent-psychophysical-techniques
#12
Anirbaan Mukherjee, Richard A Bone
BACKGROUND: Cataract, a leading cause of vision impairment, is due to the lens becoming excessively optically dense. Change in the lens optical density (LOD) could be a useful indicator of incipient nuclear cataract and would necessitate the development of accurate measurement techniques. Mapcat sf™ is a heterochromatic flicker photometer for measuring macular pigment optical density (MPOD) under photopic conditions. In the process, it also measures LOD that is needed in the calculation of MPOD...
2016: Eye and Vision (London, England)
https://www.readbyqxmd.com/read/27465913/long-term-outcome-of-cataract-surgery-in-patients-with-idiopathic-hypoparathyroidism-and-its-relationship-with-their-calcemic-status
#13
Soma Saha, Shiva Prasad Gantyala, Sameer Aggarwal, Vishnubhatla Sreenivas, Radhika Tandon, Ravinder Goswami
Cataract is a cardinal manifestation of hypoparathyroidism. Although patients with hypoparathyroidism require cataract surgery at a younger age than individuals without hypoparathyroidism, there is limited information on the outcome of this surgery. We assessed long-term complications of cataract surgery in patients with idiopathic hypoparathyroidism (IH) and its relationship with their clinical and biochemical parameters. Twenty-seven patients with IH and 25 nonhypoparathyroid controls with a minimum follow-up of 2 years after cataract surgery were assessed for visual acuity, intraocular pressure, lens centricity, Nd:YAG laser capsulotomy, and the severity of posterior capsular opacification (PCO) and anterior capsular opacification...
July 27, 2016: Journal of Bone and Mineral Metabolism
https://www.readbyqxmd.com/read/27373386/femtosecond-laser-assisted-cataract-surgery-in-complex-cases
#14
Michael J Taravella, Beeran Meghpara, Garrett Frank, William Gensheimer, Richard Davidson
PURPOSE: To describe the use of the femtosecond laser in complex cataract cases. SETTING: Department of Ophthalmology, University of Colorado, Aurora, Colorado, USA. DESIGN: Retrospective case series. METHODS: This was a single-center retrospective review of consecutive complex cataract surgery cases in which the Lensx femtosecond laser was used between October 2012 and February 2015. Complex cases were defined as white cataracts, dense brunescent cataracts, or cataracts in which zonulopathy was identified preoperatively...
June 2016: Journal of Cataract and Refractive Surgery
https://www.readbyqxmd.com/read/27347498/optical-imaging-through-dynamic-turbid-media-using-the-fourier-domain-shower-curtain-effect
#15
Eitan Edrei, Giuliano Scarcelli
Several phenomena have been recently exploited to circumvent scattering and have succeeded in imaging or focusing light through turbid layers. However, the requirement for the turbid medium to be steady during the imaging process remains a fundamental limitation of these methods. Here we introduce an optical imaging modality that overcomes this challenge by taking advantage of the so-called shower-curtain effect, adapted to the spatial-frequency domain via speckle correlography. We present high resolution imaging of objects hidden behind millimeter-thick tissue or dense lens cataracts...
January 20, 2016: Optica
https://www.readbyqxmd.com/read/27168717/regulatory-effect-of-chrysin-on-expression-of-lenticular-calcium-transporters-calpains-and-apoptotic-cascade-components-in-selenite-induced-cataract
#16
Mahalingam Sundararajan, Philip A Thomas, P Archana Teresa, Muniyandi Anbukkarasi, Pitchairaj Geraldine
PURPOSE: Selenite-induced cataract is associated with oxidative stress, loss of calcium homeostasis, activation of calpain enzymes, and apoptotic cell death in the lens. An evaluation of naturally occurring antioxidants that also restrict calcium influx into the lens and calpain activation and thus prevent lenticular cell death may lead to the development of safe and effective anticataractogenic drugs. This study focuses on a naturally occurring flavone, chrysin, and its efficacy in preventing cataractogenic changes in in vitro cultured Wistar rat lenses...
2016: Molecular Vision
https://www.readbyqxmd.com/read/27164507/postcataract-endophthalmitis-treated-with-small-gauge-vitrectomy
#17
Janelle M Fassbender, Denis Jusufbegovic, Shlomit Schaal
PURPOSE: To discuss the use of minimally invasive, small gauge vitrectomy for acute postcataract endophthalmitis in patients with better than light-perception vision. PATIENT: 71-year-old man presented with redness, pain, and decreased vision of his left eye 11 days after cataract extraction. His visual acuity was counting fingers at 1 foot and slit-lamp examination revealed severe conjunctival injection, corneal edema, and hypopyon. The clinical impression was of acute postcataract endophthalmitis...
2016: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/27130482/30%C3%A2-years-after-the-chernobyl-nuclear-accident-time-for-reflection-and-re-evaluation-of-current-disaster-preparedness-plans
#18
Lydia B Zablotska
It has been 30 years since the worst accident in the history of the nuclear era occurred at the Chernobyl power plant in Ukraine close to densely populated urban areas. To date, epidemiological studies reported increased long-term risks of leukemia, cardiovascular diseases, and cataracts among cleanup workers and of thyroid cancer and non-malignant diseases in those exposed as children and adolescents. Mental health effects were the most significant public health consequence of the accident in the three most contaminated countries of Ukraine, Belarus, and the Russian Federation...
June 2016: Journal of Urban Health: Bulletin of the New York Academy of Medicine
https://www.readbyqxmd.com/read/27113881/biometry-with-a-new-swept-source-optical-coherence-tomography-biometer-repeatability-and-agreement-with-an-optical-low-coherence-reflectometry-device
#19
Mathew Kurian, Nikhil Negalur, Sudeep Das, Narendra K Puttaiah, Dhawal Haria, Tejal S J, Maithil M Thakkar
PURPOSE: To assess the repeatability of a new swept-source optical coherence tomography (SS-OCT) biometer (IOLMaster 700) and evaluate the agreement with an optical low-coherence reflectometry (OLCR) biometer (Lenstar 900) in cataractous eyes. SETTING: Tertiary eyecare facility. DESIGN: Prospective evaluation of a diagnostic test. METHODS: Eyes of patients had 3 consecutive scans acquired by the same operator. The repeatability of measurements was assessed using the within-subject standard deviation and coefficient of variation (CoV)...
April 2016: Journal of Cataract and Refractive Surgery
https://www.readbyqxmd.com/read/27052457/stability-of-protein-specific-hydration-shell-on-crowding
#20
Kuo-Ying Huang, Carolyn N Kingsley, Ryan Sheil, Chi-Yuan Cheng, Jan C Bierma, Kyle W Roskamp, Domarin Khago, Rachel W Martin, Songi Han
We demonstrate that the effect of protein crowding is critically dependent on the stability of the protein's hydration shell, which can dramatically vary between different proteins. In the human eye lens, γS-crystallin (γS-WT) forms a densely packed transparent hydrogel with a high refractive index, making it an ideal system for studying the effects of protein crowding. A single point mutation generates the cataract-related variant γS-G18V, dramatically altering the optical properties of the eye lens. This system offers an opportunity to explore fundamental questions regarding the effect of protein crowding, using γS-WT and γS-G18V: (i) how do the diffusion dynamics of hydration water change as a function of protein crowding?; and (ii) upon hydrogel formation of γS-WT, has a dynamic transition occurred generating a single population of hydration water, or do populations of bulk and hydration water coexist? Using localized spin probes, we separately probe the local translational diffusivity of both surface hydration and interstitial water of γS-WT and γS-G18V in solution...
April 27, 2016: Journal of the American Chemical Society
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