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Sexuality in elderly

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https://www.readbyqxmd.com/read/28104184/elder-abuse-prevalence-in-community-settings-a-systematic-review-and-meta-analysis
#1
Yongjie Yon, Christopher R Mikton, Zachary D Gassoumis, Kathleen H Wilber
BACKGROUND: Elder abuse is recognised worldwide as a serious problem, yet quantitative syntheses of prevalence studies are rare. We aimed to quantify and understand prevalence variation at the global and regional levels. METHODS: For this systematic review and meta-analysis, we searched 14 databases, including PubMed, PsycINFO, CINAHL, EMBASE, and MEDLINE, using a comprehensive search strategy to identify elder abuse prevalence studies in the community published from inception to June 26, 2015...
February 2017: Lancet Global Health
https://www.readbyqxmd.com/read/28064116/sex-specific-and-inter-individual-differences-in-biomarkers-of-selenium-status-identified-by-a-calibrated-elisa-for-selenoprotein-p
#2
Sandra Hybsier, Torsten Schulz, Zida Wu, Ilja Demuth, Waldemar B Minich, Kostja Renko, Eddy Rijntjes, Josef Köhrle, Christian J Strasburger, Elisabeth Steinhagen-Thiessen, Lutz Schomburg
Selenoprotein P (SELENOP) is a liver-derived transporter of selenium (Se) in blood, and a meaningful biomarker of Se status. Se is an essential trace element for the biosynthesis of enzymatically-active selenoproteins, protecting the organism from oxidative damage. The usage of uncalibrated assays hinders the comparability of SELENOP concentrations and their pathophysiological interpretation across different clinical studies. On this account, we established a new sandwich SELENOP-ELISA and calibrated against a standard reference material (SRM1950)...
December 29, 2016: Redox Biology
https://www.readbyqxmd.com/read/28053897/effects-of-a-supplement-combining-pycnogenol-%C3%A2-and-l-arginine-aspartate-on-lower-urinary-dysfunction-compared-with-saw-palmetto-extract
#3
Hiroshi Yagi, Ryo Sato, Kojiro Nishio, Gaku Arai, Shigehiro Soh, Hiroshi Okada
OBJECTIVES: Lower urinary tract symptoms (LUTS) and sexual dysfunction (SDys) are common problems that affect quality of life (QOL) in elderly men. In addition to prescribed drugs, many over-the-counter medications including supplements are used to treat QOL diseases. Phosphodiesterase inhibitors are reported to be effective for both LUTS and SDys by increasing nitric oxide levels. French maritime pine bark extract Pycnogenol(®), which is a potent nitric oxide donor, is reported to be effective for SDys...
January 2017: Journal of Traditional and Complementary Medicine
https://www.readbyqxmd.com/read/28053363/global-research-priorities-for-interpersonal-violence-prevention-a-modified-delphi-study
#4
Christopher R Mikton, Masako Tanaka, Mark Tomlinson, David L Streiner, Lil Tonmyr, Bandy X Lee, Jane Fisher, Kathy Hegadoren, Joam Evans Pim, Shr-Jie Sharlenna Wang, Harriet L MacMillan
OBJECTIVE: To establish global research priorities for interpersonal violence prevention using a systematic approach. METHODS: Research priorities were identified in a three-round process involving two surveys. In round 1, 95 global experts in violence prevention proposed research questions to be ranked in round 2. Questions were collated and organized according to the four-step public health approach to violence prevention. In round 2, 280 international experts ranked the importance of research in the four steps, and the various substeps, of the public health approach...
January 1, 2017: Bulletin of the World Health Organization
https://www.readbyqxmd.com/read/28029675/an-overview-of-menopausal-symptoms-in-a-district-hospital-of-nepal
#5
S Gupta, K Acharya, P Srivastav, P K Gurung, N Gupta
INTRODUCTION: Menopause is a universal reproductive phenomenon which confirms the end of fertility of the women. The objectives of this study were to establish the age of natural menopause and to identify the prevalence of menopausal symptoms among the rural women attending district hospital of Nepal. METHODS: This present study is a hospital based, observational cross-sectional study conducted in Outpatient department of Lamjung District Hospital, Lamjung, Nepal...
October 2016: JNMA; Journal of the Nepal Medical Association
https://www.readbyqxmd.com/read/27993663/risks-of-serious-toxicities-from-intermittent-versus-continuous-androgen-deprivation-therapy-for-advanced-prostate-cancer-patients-a-population-based-study
#6
Huei-Ting Tsai, Ruth M Pfeiffer, George K Philips, Ana Barac, Alex Z Fu, David F Penson, Yingjun Zhou, Arnold L Potosky
PURPOSE: Randomized trials have reported that intermittent androgen deprivation therapy (IADT) for patients with advanced prostate cancer (PCa) may improve sexual and physical functioning compared to continuous ADT (CADT) without compromising survival. It is unknown whether IADT alters the risk of serious toxicities associated with CADT. MATERIALS AND METHODS: We conducted a population-based cohort study of 9,772 men aged 66 or older diagnosed with advanced PCa from 2002-2011 treated with ADT...
December 16, 2016: Journal of Urology
https://www.readbyqxmd.com/read/27988927/cardiac-remodelling-in-a-baboon-model-of-intrauterine-growth-restriction-mimics-accelerated-ageing
#7
Anderson H Kuo, Cun Li, Jinqi Li, Hillary F Huber, Peter W Nathanielsz, Geoffrey D Clarke
KEY POINTS: Rodent models of intrauterine growth restriction (IUGR) successfully identify mechanisms that can lead to short-term and long-term detrimental cardiomyopathies but differences between rodent and human cardiac physiology and placental-fetal development indicate a need for models in precocial species for translation to human development. We developed a baboon model for IUGR studies using a moderate 30% global calorie restriction of pregnant mothers and used cardiac magnetic resonance imaging to evaluate offspring heart function in early adulthood...
November 6, 2016: Journal of Physiology
https://www.readbyqxmd.com/read/27975301/vertebral-cross-sectional-area-an-orphan-phenotype-with-potential-implications-for-female-spinal-health
#8
REVIEW
T A L Wren, S Ponrartana, V Gilsanz
A high priority in imaging-based research is the identification of the structural basis that confers greater risk for spinal disorders. New evidence indicates that factors related to sex influence the fetal development of the axial skeleton. Girls are born with smaller vertebral cross-sectional area compared to boys-a sexual dimorphism that is present throughout life and independent of body size. The smaller female vertebra is associated with greater flexibility of the spine that could represent the human adaptation to fetal load...
December 14, 2016: Osteoporosis International
https://www.readbyqxmd.com/read/27925091/aids-in-the-elderly-reasons-that-lead-to-late-diagnosis
#9
Rúbia Aguiar Alencar, Suely Itsuko Ciosak
Objective: to investigate elderly living with HIV/Aids and health professionals, what are the reasons that lead to late diagnosis of HIV infection in the elderly. Method: prospective, qualitative study, conducted at a specialized outpatient clinic with elderly living with HIV/Aids, diagnosed age over 60 years and in the Family Health Strategy units with nurses and physicians. Data were collected through interviews and verified by content analysis, using the theoretical framework of vulnerability...
November 2016: Revista Brasileira de Enfermagem
https://www.readbyqxmd.com/read/27900934/gender-relations-and-women-s-reproductive-health-in-south-sudan
#10
Sumit Kane, Matilda Rial, Anthony Matere, Marjolein Dieleman, Jacqueline E W Broerse, Maryse Kok
BACKGROUND: In South Sudan, women disproportionately bear the burden of morbidity and mortality related to sexual and reproductive health, with a maternal mortality ratio of 789 deaths per 100,000 live births. DESIGN: A qualitative study was conducted to analyze how gendered social relations among the Fertit people affect women's ability to exercise control over their reproductive lives and thereby their sexual and reproductive health. Transcripts of 5 focus group discussions and 44 semi-structured interviews conducted with purposefully selected community members and health personnel were analyzed using Connell's relational theory of gender...
2016: Global Health Action
https://www.readbyqxmd.com/read/27872000/is-testosterone-a-food-for-the-brain
#11
REVIEW
Giacomo Ciocca, Erika Limoncin, Eleonora Carosa, Stefania Di Sante, Giovanni L Gravina, Daniele Mollaioli, Daniele Gianfrilli, Andrea Lenzi, Emmanuele A Jannini
INTRODUCTION: Testosterone is fundamental for psychological, sexological, cognitive, and reproductive aspects, and its lack or reduction largely impacts the quality of life in males and females. AIM: Therefore, the aim of this review is to describe the role of testosterone in the neurophysiology of the brain and related aspects regarding the quality of general and sexual life. METHODS: We listed and discussed the principal studies on the role of testosterone in the brain regarding sexual health, psychopathological conditions, and the elderly...
January 2016: Sexual Medicine Reviews
https://www.readbyqxmd.com/read/27871024/is-it-time-to-address-survivorship-in-advanced-breast-cancer-a-review-article
#12
REVIEW
Simona Di Lascio, Olivia Pagani
The outcome of advanced breast cancer has significantly improved over recent decades. As a consequence, the complex needs of patients living with the disease and their care-givers should be addressed not only in terms of supportive and palliative care but also of "survivorship" requirements. The multidisciplinary approach to advanced breast cancer should encompass - early in the history of the disease - not only physical but also functional, social, psychological and spiritual domains. It is important to clearly define the disease context with patients and families ("chronic" preferred to "incurable"), addressing the concept of uncertainty, and tailoring the treatment strategy according to both disease status and individual priorities...
February 2017: Breast: Official Journal of the European Society of Mastology
https://www.readbyqxmd.com/read/27858878/association-between-pulmonary-fibrosis-and-osteoporosis-in-the-elderly-people-a-case-control-study
#13
Zhong Xie, Yanhong He, Yongqiang Sun, Zhanzhan Lin, Mingzhi Yang, Qian Liu, Sihai Liu
In this case-control study, we evaluated the association between osteoporosis and pulmonary fibrosis in the elderly. Participants were divided into a test group and a control group depending on bone mineral density and grid pattern changes of pulmonary fibrosis. We measured general conditions, related risk factors, serum biochemical index, grid pattern changes of double lungs, pulmonary function, arterial oxygen pressure (PO2), and bone mineral density of participates, and investigated the data through statistical analysis on SPSS 17...
November 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27843074/testosterone-threshold-for-increased-cardiovascular-risk-in-middle-aged-and-elderly-men-a-locally-weighted-regression-analysis
#14
Pin-Wen Liao, Chia-Chang Wu, Kuan-Chou Chen, Fu-Shan Jaw, Hong-Jeng Yu, Shih-Ping Liu, Chen-Hsun Ho
INTRODUCTION: Although testosterone deficiency has a well-known association with increased risk of cardiovascular disease (CVD), the threshold remains to be determined. AIM: To investigate whether there is a discriminatory testosterone level below which the CVD risk increases. METHODS: The study included 876 men 45 to 74 years old who underwent a general health checkup. The Framingham Risk Score was used to estimate the 10-year CVD risk; a high-sensitivity C-reactive protein (hsCRP) level of at least 1 mg/L was considered an indicator of increased CVD risk...
December 2016: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/27834003/prediction-of-rehabilitation-needs-after-treatment-of-cervical-cancer-what-do-late-adverse-effects-tell-us
#15
Tina Broby Mikkelsen, Bente Sørensen, Karin B Dieperink
PURPOSE: Women treated for cervical cancer with radiotherapy and chemotherapy have reported serious bowel, vaginal, and sexual late effects. The purpose of this study was to describe late adverse effects, health-related quality of life, and self-efficacy in a representative Danish cervical cancer population in order to describe rehabilitation needs. METHODS: Women, mean age 55 years, treated for cervical cancer from January 2010 to July 2013, who were alive and without known relapse/metastases were included in this cross-sectional study...
November 10, 2016: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/27828566/factors-associated-with-the-vulnerability-of-older-people-living-with-hiv-aids-in-belo-horizonte-mg-brazil
#16
Marília Borborema Rodrigues Cerqueira, Roberto Nascimento Rodrigues
The objective of this article was to identify the factors associated with the vulnerability of the elderly aged 60 years or older to HIV/AIDS, based on the perspective of older people living with the virus. Interviews were conducted with 20 participants, including 12 women and eight men, who were patients from a public hospital in Belo Horizonte, Minas Gerais, Brazil. The elderly interviewed had a low education level and low income, were currently or previously in a marital union, had perceptions and behaviors grounded in structural gender relations with power asymmetry and had a low capacity to respond to vulnerability...
November 2016: Ciência & Saúde Coletiva
https://www.readbyqxmd.com/read/27807202/estrogens-and-androgens-in-skeletal-physiology-and-pathophysiology
#17
REVIEW
Maria Almeida, Michaël R Laurent, Vanessa Dubois, Frank Claessens, Charles A O'Brien, Roger Bouillon, Dirk Vanderschueren, Stavros C Manolagas
Estrogens and androgens influence the growth and maintenance of the mammalian skeleton and are responsible for its sexual dimorphism. Estrogen deficiency at menopause or loss of both estrogens and androgens in elderly men contribute to the development of osteoporosis, one of the most common and impactful metabolic diseases of old age. In the last 20 years, basic and clinical research advances, genetic insights from humans and rodents, and newer imaging technologies have changed considerably the landscape of our understanding of bone biology as well as the relationship between sex steroids and the physiology and pathophysiology of bone metabolism...
January 2017: Physiological Reviews
https://www.readbyqxmd.com/read/27782784/prevalence-estimates-and-correlates-of-elder-abuse-in-the-united-states-the-national-intimate-partner-and-sexual-violence-survey
#18
Andre B Rosay, Carrie F Mulford
This study examines the prevalence and correlates of psychological abuse and physical abuse against women and men aged 70 or older. Self-report data from 2,185 respondents in the 2010 National Intimate Partner and Sexual Violence Survey (NISVS) were used to create weighted estimates for past-year experiences of abuse. Correlates were then examined using survey logistic regression models. More than 1 in 10 adults who are 70 years of age or older (14.0%) have experienced some form of abuse in the past year, with 12...
October 26, 2016: Journal of Elder Abuse & Neglect
https://www.readbyqxmd.com/read/27771698/elder-abuse-in-nursing-homes-do-special-care-units-make-a-difference-a-secondary-data-analysis-of-the-swiss-nursing-homes-human-resources-project
#19
Olivia Blumenfeld Arens, Katharina Fierz, Franziska Zúñiga
BACKGROUND: In special care units (SCUs) for residents with advanced dementia, both personnel and organizations are adapted to the needs of residents. However, whether these adaptations have a preventive effect on elder abuse has not yet been explored. OBJECTIVE: To describe the prevalence of observed emotional abuse, neglect, and physical abuse in Swiss nursing homes, to compare SCUs with non-SCUs concerning the frequency of observed emotional abuse, neglect, and physical abuse, and to explore how resident-related characteristics, staff outcomes/characteristics, and organizational/environmental factors relate to observed elder abuse...
October 22, 2016: Gerontology
https://www.readbyqxmd.com/read/27761111/sexual-dimorphism-and-aging-in-the-human-hyppocampus-identification-validation-and-impact-of-differentially-expressed-genes-by-factorial-microarray-and-network-analysis
#20
Daniel V Guebel, Néstor V Torres
Motivation: In the brain of elderly-healthy individuals, the effects of sexual dimorphism and those due to normal aging appear overlapped. Discrimination of these two dimensions would powerfully contribute to a better understanding of the etiology of some neurodegenerative diseases, such as "sporadic" Alzheimer. Methods: Following a system biology approach, top-down and bottom-up strategies were combined. First, public transcriptome data corresponding to the transition from adulthood to the aging stage in normal, human hippocampus were analyzed through an optimized microarray post-processing (Q-GDEMAR method) together with a proper experimental design (full factorial analysis)...
2016: Frontiers in Aging Neuroscience
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