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https://www.readbyqxmd.com/read/28239012/neighborhood-trauma-due-to-violence-a-multilevel-analysis
#1
Sandra D Lane, Robert A Rubinstein, Dessa Bergen-Cico, Timothy Jennings-Bey, Linda Stone Fish, David A Larsen, Mindy Thompson Fullilove, Tracey Reichert Schimpff, Kishi Animashaun Ducre, Jonnell Allen Robinson
In Syracuse, New York the social determinants of trauma from neighborhood violence are rooted in historical processes, including urban renewal, the Rockefeller drug laws, and de-industrialization. These contributed to destabilizing Syracuse communities of color, resulting in disproportionate incarceration, family disruption, and economic devastation. Community violence, clustering in densely populated neighborhoods, creates unmanageable stress for the families who live in them. A map of gunshots and gun fatalities (2009 to 2014) illustrates the continuing onslaught of bullets being fired, often in close proximity to elementary schools...
2017: Journal of Health Care for the Poor and Underserved
https://www.readbyqxmd.com/read/28237760/differentiating-suicide-decedents-who-died-using-firearms-from-those-who-died-using-other-methods
#2
Michael D Anestis, Lauren R Khazem, Joye C Anestis
Studies have documented a link between gun ownership and suicide, but little is known about characteristics of those most likely to use a gun in a suicide attempt rather than alternative methods. We examined which factors differentiate suicide decedents who died using a gun from those who died by other methods. We further examined whether such findings are consistent within the subcomponent of our larger sample comprised entirely of gun owning suicide decedents. Data reflect 267 suicide decedents, with data provided by individuals who identified as having lost someone to suicide (loss survivors)...
February 22, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28235643/evolutionary-and-epidemiological-analyses-based-on-spike-genes-of-porcine-epidemic-diarrhea-virus-circulating-in-thailand-in-2008-2015
#3
Christopher J Stott, Gun Temeeyasen, Thitima Tripipat, Pavita Kaewprommal, Angkana Tantituvanont, Jittima Piriyapongsa, Dachrit Nilubol
Porcine epidemic diarrhea (PED) has been endemic causing sporadic outbreaks in Thailand since 2007. In 2014-2015, several herds had experienced severe PED outbreaks and the reason of the re-current outbreaks was unknown. Whether or not the introduction of exotic strains or continual evolution of existing PEDV, genetic analyses would provide a more understanding in its evolutionary pattern. In the study, 117 complete spike gene sequences of Thai PED virus (PEDV) collected from 2008 to 2015 were clustered along with 95 references of PEDV spike sequences, and analyzed with the US sequences dataset (n=99)...
February 21, 2017: Infection, Genetics and Evolution
https://www.readbyqxmd.com/read/28233974/geo2-thin-film-deposition-on-graphene-oxide-by-the-hydrogen-peroxide-route-evaluation-for-lithium-ion-battery-anode
#4
Alexander G Medvedev, Alexey A Mikhaylov, Dmitry A Grishanov, Denis Yau Wai Yu, Jenny Gun, Sergey Sladkevich, Ovadia Lev, Petr V Prikhodchenko
A peroxogermanate thin film was deposited in high yield at room temperature on graphene oxide (GO) from peroxogermanate sols. The deposition of the peroxo-precursor onto graphene oxide and the transformations to amorphous GeO2, crystalline tetragonal GeO2 and then to cubic elemental germanium were followed by electron microscopy, XRD and XPS. All of these transformations are influenced by the graphene oxide support. The initial deposition is explained in view of the sol composition and the presence of graphene oxide, and the different thermal transformations are explained by reactions with the graphene support acting as a reducing agent...
February 24, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28233602/how-effectively-do-hydraulic-calcium-silicate-cements-re-mineralize-demineralized-dentin
#5
Xin Li, Jan De Munck, Kirsten Van Landuyt, Mariano Pedano, Zhi Chen, Bart Van Meerbeek
OBJECTIVE: To characterize the chemical interplay and to quantify the re-mineralization potential of hydraulic calcium-silicate cements (hCSCs) at demineralized dentin. METHODS: Pairs of class-I cavities were prepared in non-carious human third molars. One dentin cavity was demineralized with 10% formic acid (5h); the other served as control. The cavities were filled with two resin-free hCSCs (Biodentine, Septodont; ProRoot MTA, Dentsply Sirona) or one resin-based hCSC (TheraCal LC, Bisco)...
February 20, 2017: Dental Materials: Official Publication of the Academy of Dental Materials
https://www.readbyqxmd.com/read/28232304/trump-s-mental-health-gun-laws-and-health-insurance
#6
Michael McCarthy
No abstract text is available yet for this article.
February 23, 2017: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/28231942/atherothrombotic-risk-stratification-and-ezetimibe-for-secondary-prevention
#7
Erin A Bohula, David A Morrow, Robert P Giugliano, Michael A Blazing, Ping He, Jeong-Gun Park, Sabina A Murphy, Jennifer A White, Y Antero Kesaniemi, Terje R Pedersen, Adrian J Brady, Yale Mitchel, Christopher P Cannon, Eugene Braunwald
BACKGROUND: Ezetimibe improves cardiovascular (CV) outcomes in patients stabilized after acute coronary syndrome (ACS) when added to statin therapy. After ACS, patients vary considerably in their risk for recurrent CV events. OBJECTIVES: This study tested the hypothesis that atherothrombotic risk stratification may be useful to identify post-ACS patients who have the greatest potential for benefit from the addition of ezetimibe to statin therapy. METHODS: The TIMI (Thrombolysis In Myocardial Infarction) Risk Score for Secondary Prevention (TRS 2°P) is a simple 9-point risk stratification tool, previously developed in a large population with atherothrombosis to predict CV death, myocardial infarction (MI), and ischemic stroke (CV death/MI/ischemic cerebrovascular accident [iCVA])...
February 28, 2017: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/28230743/quasi-static-calibration-method-of-a-high-g-accelerometer
#8
Yan Wang, Jinbiao Fan, Jing Zu, Peng Xu
To solve the problem of resonance during quasi-static calibration of high-g accelerometers, we deduce the relationship between the minimum excitation pulse width and the resonant frequency of the calibrated accelerometer according to the second-order mathematical model of the accelerometer, and improve the quasi-static calibration theory. We establish a quasi-static calibration testing system, which uses a gas gun to generate high-g acceleration signals, and apply a laser interferometer to reproduce the impact acceleration...
February 20, 2017: Sensors
https://www.readbyqxmd.com/read/28224817/is-the-recurrence-rate-of-chronic-subdural-hematomas-dependent-on-the-duration-of-drainage
#9
Aydemir Kale, İbrahim İlker Öz, Eren Görkem Gün, Murat Kalaycı, Şanser Gül
OBJECTIVES: Chronic subdural hematoma (CSDH) is the most frequent type of intracranial hemorrhage which especially affects the elderly. Various surgical techniques have been reported for CSDH treatment; optimal treatment methods are still controversial. In this study, the effects of long drainage durations on results and recurrences were investigated in patients on whom closed system drainage with burr hole craniotomy was applied due to CSDH. METHODS: 90 patients with 105 CSDH were operated between 2008 and 2016...
February 22, 2017: Neurological Research
https://www.readbyqxmd.com/read/28223753/five-cases-of-phytophotodermatitis-caused-by-fig-leaves-and-relevant-literature-review
#10
Jin-Hwa Son, Hyunju Jin, Hyang-Suk You, Woo-Haing Shim, Jeong-Min Kim, Gun-Wook Kim, Hoon-Soo Kim, Hyun-Chang Ko, Moon-Bum Kim, Byung-Soo Kim
Phytophotodermatitis is a condition caused by sequential exposure to photosensitizing substances present in plants followed by ultraviolet light. Several plants (e.g., limes, celery, fig, and wild parsnip) contain furocoumarin compounds (psoralens). It is important for dermatologists to be aware of phytophotodermatitis because it may be misdiagnosed as cellulitis, tinea, or allergic contact dermatitis. We present five patients with a sharply defined erythematous swollen patch with bullae on both feet. They described soaking their feet in a fig leaves decoction to treat their underlying dermatologic diseases...
February 2017: Annals of Dermatology
https://www.readbyqxmd.com/read/28223739/effectiveness-of-specific-sublingual-immunotherapy-in-korean-patients-with-atopic-dermatitis
#11
Hyang-Suk You, Min-Young Yang, Gun-Wook Kim, Hyun-Ho Cho, Won-Jeong Kim, Je-Ho Mun, Margaret Song, Hoon-Soo Kim, Hyun-Chang Ko, Moon-Bum Kim, Byung-Soo Kim
BACKGROUND: Sublingual immunotherapy (SLIT) with house dust mites (HDM) preparation has recently been proven to be beneficial for treating allergic rhinitis and asthma. However, there has been no report regarding the efficacy and safety of SLIT in Korean patients with atopic dermatitis (AD). OBJECTIVE: We intended to investigate the efficacy and safety of SLIT in Korean patients with AD. METHODS: A total of 34 patients with AD and immunoglobulin E (IgE)-proven HDM sensitization (Class ≥3) were recruited...
February 2017: Annals of Dermatology
https://www.readbyqxmd.com/read/28222511/evaluation-of-a-dna-a%C3%AE-42-vaccine-in-aged-nzw-rabbits-antibody-kinetics-and-immune-profile-after-intradermal-immunization-with-full-length-dna-a%C3%AE-42-trimer
#12
Doris Lambracht-Washington, Min Fu, Mary Wight-Carter, Matthew Riegel, Roger N Rosenberg
A pathological hallmark of Alzheimer's disease (AD) are amyloid plaques in the brain consisting of aggregated amyloid-β 42 peptide (Aβ42) derived from cellular amyloid-β protein precursor (AβPP). Based on successful experiments in mouse AD models, active immunization with Aβ42 peptide and passive immunizations with anti-Aβ42 antibodies were started in clinical trials. Active Aβ42 peptide immunization in humans had led to an inflammatory autoimmune response, and the trial was stopped. Passive immunizations had shown some effects in slowing AD pathology...
February 7, 2017: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/28221199/emerging-technologies-let-s-not-jump-the-gun
#13
Yafen Liang, John L Smith, Mark J Rice
No abstract text is available yet for this article.
February 17, 2017: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/28217867/effects-of-25-hydroxyvitamin-d-and-vitamin-d-binding-protein-on-bone-mineral-density-and-disease-activity-in-malaysian-patients-with-rheumatoid-arthritis
#14
Tze Hao Wong, Esha Das Gupta, Ammu K Radhakrishnan, Suk Chyn Gun, Gandhi Chembalingam, Swan Sim Yeap
AIM: Vitamin D3 [25(OH)D] has been shown to be important in bone health and can influence rheumatoid arthritis (RA) disease activity. Vitamin D-binding protein (VDBP) levels vary with race and may modulate 'bioavailable' levels of 25(OH)D. The aim of this study was to explore the relationships between 25(OH)D, VDBP and clinical factors on bone mineral density (BMD) in a group of multi-ethnic Malaysian RA patients and healthy controls. METHODS: A cross-sectional study of 77 female RA patients and 29 controls was performed...
February 20, 2017: International Journal of Rheumatic Diseases
https://www.readbyqxmd.com/read/28217684/extrauterine-epithelioid-trophoblastic-tumor-in-hysterectomized-woman
#15
Ji-Hye Kim, Sun Kyung Lee, Soo Hyun Hwang, Jung-Sun Kim, Gun Yoon, Yoo-Young Lee, Tae-Joong Kim, Chel Hun Choi, Byoung-Gie Kim, Duk-Soo Bae, Jeong-Won Lee
Epithelioid trophoblastic tumor (ETT) is a very rare variant of gestational trophoblastic disease (GTD) which arises in reproductive age women with prior gestational history. Although abnormal vaginal bleeding is the most common symptom of ETT, there are no reported pathognomonic symptoms of ETT because of its rarity. ETT is similar to placental site trophoblastic tumor in terms of its slow growing characteristic and microscopic findings. Therefore, it could be misdiagnosed as placental site trophoblastic tumor or other types of GTD...
January 2017: Obstetrics & Gynecology Science
https://www.readbyqxmd.com/read/28217683/lymphoepithelioma-like-carcinoma-of-the-uterine-cervix
#16
Hyun Sil Yun, Sun Kyung Lee, Gun Yoon, Hwi Gon Kim, Dong Hyung Lee, Yong Jin Na, Ook Hwan Choi, Dong Hoon Shin, Yong Jung Song
Lymphoepithelioma-like carcinoma (LELC) of the uterine cervix is exceedingly uncommon. We herein report a rare case of cervical LELC. A 45-year-old woman was admitted to gynecology department with vaginal bleeding for one month. Liquid-based cytology revealed atypical endometrial cells, not otherwise specified on her cervix. On a hysteroscopy, an endocervical mass was identified and the pathologic result was consistent with poorly differentiated squamous cell carcinoma. Magnetic resonance imaging and positron emission tomography with 2-deoxy-2-[fluorine-18] fluoro-D-glucose integrated with computed tomography revealed a 3...
January 2017: Obstetrics & Gynecology Science
https://www.readbyqxmd.com/read/28216317/tropomyosin-isoforms-specify-functionally-distinct-actin-filament-populations-in%C3%A2-vitro
#17
Gergana Gateva, Elena Kremneva, Theresia Reindl, Tommi Kotila, Konstantin Kogan, Laurène Gressin, Peter W Gunning, Dietmar J Manstein, Alphée Michelot, Pekka Lappalainen
Actin filaments assemble into a variety of networks to provide force for diverse cellular processes [1]. Tropomyosins are coiled-coil dimers that form head-to-tail polymers along actin filaments and regulate interactions of other proteins, including actin-depolymerizing factor (ADF)/cofilins and myosins, with actin [2-5]. In mammals, >40 tropomyosin isoforms can be generated through alternative splicing from four tropomyosin genes. Different isoforms display non-redundant functions and partially non-overlapping localization patterns, for example within the stress fiber network [6, 7]...
February 14, 2017: Current Biology: CB
https://www.readbyqxmd.com/read/28214795/pre-implantation-balloon-aortic-valvuloplasty-and-clinical-outcomes-following-transcatheter-aortic-valve-implantation-a-propensity-score-analysis-of-the-uk-registry
#18
Glen P Martin, Matthew Sperrin, Rodrigo Bagur, Mark A de Belder, Iain Buchan, Mark Gunning, Peter F Ludman, Mamas A Mamas
BACKGROUND: Aortic valve predilation with balloon aortic valvuloplasty (BAV) is recommended before transcatheter aortic valve implantation (TAVI), despite limited data around the requirement of this preprocedural step and the potential risks of embolization. This study aimed to investigate the trends in practice and associations of BAV on short-term outcomes in the UK TAVI registry. METHODS AND RESULTS: Eleven clinical endpoints were investigated, including 30-day mortality, myocardial infarction, aortic regurgitation, valve dysfunction, and composite early safety...
February 18, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/28214341/angiopoietin-2-enhances-osteogenic-differentiation-of-bone-marrow-stem-cells
#19
Mi-Lan Kang, Eun-Ah Kim, Se-Young Jeong, Gun-Il Im
Our previous studies revealed that co-transplantation of bone marrow stem cells (BMSCs) and adipose-derived stem cells (ADSCs) can enhance bone regeneration and angiogenesis. However, it is unclear which genes are involved in the regulation of osteogenesis and/or angiogenesis during the co-culturing of BMSCs and ADSCs. The expression patterns of genes associated with osteogenesis and/or angiogenesis were analyzed in osteogenesis-induced BMSCs and ADSCs using an oligonucleotide microarray. Significant difference in the expression patterns of several genes were identified from hierarchical clustering and analyzed on co-cultured BMSCs and ADSCs...
February 18, 2017: Journal of Cellular Biochemistry
https://www.readbyqxmd.com/read/28210633/potential-usefulness-of-streptococcus-pneumoniae-extracellular-membrane-vesicles-as-antibacterial-vaccines
#20
Chi-Won Choi, Edmond Changkyun Park, Sung Ho Yun, Sang-Yeop Lee, Seung Il Kim, Gun-Hwa Kim
The secretion of extracellular membrane vesicles (EMVs) is a common phenomenon that occurs in archaea, bacteria, and mammalian cells. The EMVs of bacteria play important roles in their virulence, biogenesis mechanisms, and host cell interactions. Bacterial EMVs have recently become the focus of attention because of their potential as highly effective vaccines that cause few side effects. Here, we isolated the EMVs of Streptococcus pneumoniae and examined their potential as new vaccine candidates. Although the S...
2017: Journal of Immunology Research
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