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JOURNAL ARTICLE
Marco A F Pimentel, Alistair Johnson, Julie Lorraine Darbyshire, Lionel Tarassenko, David A Clifton, Andrew Walden, Ian Rechner, Peter J Watkinson, J Duncan Young
RATIONALE: Intensive care units (ICUs) admit the most severely ill patients. Once these patients are discharged from the ICU to a step-down ward, they continue to have their vital signs monitored by nursing staff, with Early Warning Score (EWS) systems being used to identify those at risk of deterioration. OBJECTIVES: We report the development and validation of an enhanced continuous scoring system for predicting adverse events, which combines vital signs measured routinely on acute care wards (as used by most EWS systems) with a risk score of a future adverse event calculated on discharge from the ICU...
April 12, 2024: BMJ Open
#2
Matthew M Churpek, Kyle A Carey, Ashley Snyder, Christopher J Winslow, Emily Gilbert, Nirav S Shah, Brian W Patterson, Majid Afshar, Alan Weiss, Devendra N Amin, Deborah J Rhodes, Dana P Edelson
RATIONALE: Early detection of clinical deterioration using early warning scores may improve outcomes. However, most implemented scores were developed using logistic regression, only underwent retrospective internal validation, and were not tested in important patient subgroups. OBJECTIVES: To develop a gradient boosted machine model (eCARTv5) for identifying clinical deterioration and then validate externally, test prospectively, and evaluate across patient subgroups...
March 19, 2024: medRxiv
#3
JOURNAL ARTICLE
Steve Goodacre, Laura Sutton, Kate Ennis, Ben Thomas, Olivia Hawksworth, Khurram Iftikhar, Susan J Croft, Gordon Fuller, Simon Waterhouse, Daniel Hind, Matt Stevenson, Mike J Bradburn, Michael Smyth, Gavin D Perkins, Mark Millins, Andy Rosser, Jon Dickson, Matthew Wilson
BACKGROUND: Guidelines for sepsis recommend treating those at highest risk within 1 hour. The emergency care system can only achieve this if sepsis is recognised and prioritised. Ambulance services can use prehospital early warning scores alongside paramedic diagnostic impression to prioritise patients for treatment or early assessment in the emergency department. OBJECTIVES: To determine the accuracy, impact and cost-effectiveness of using early warning scores alongside paramedic diagnostic impression to identify sepsis requiring urgent treatment...
March 2024: Health Technology Assessment: HTA
#4
JOURNAL ARTICLE
Jim Briggs, Ina Kostakis, Paul Meredith, Chiara Dall'ora, Julie Darbyshire, Stephen Gerry, Peter Griffiths, Jo Hope, Jeremy Jones, Caroline Kovacs, Rob Lawrence, David Prytherch, Peter Watkinson, Oliver Redfern
BACKGROUND: The frequency at which patients should have their vital signs (e.g. blood pressure, pulse, oxygen saturation) measured on hospital wards is currently unknown. Current National Health Service monitoring protocols are based on expert opinion but supported by little empirical evidence. The challenge is finding the balance between insufficient monitoring (risking missing early signs of deterioration and delays in treatment) and over-observation of stable patients (wasting resources needed in other aspects of care)...
March 2024: Health Soc Care Deliv Res
#5
JOURNAL ARTICLE
Cerisa Obern, Matts Olovsson, Tanja Tydén, Inger Sundström-Poromaa
OBJECTIVE: To investigate whether an early need of hormonal contraceptive (HC), or a failure to find a suitable method, are warning signs for endometriosis. DESIGN: A retrospective cohort study. SETTING: Sweden. POPULATION: The cohort consisted of 720 805 women aged 12-27 years during the period 2005-2017. All women, regardless of whether they received a diagnosis of endometriosis or not (reference group), were included...
March 21, 2024: BJOG: An International Journal of Obstetrics and Gynaecology
#6
JOURNAL ARTICLE
Ozge Yildirim, Aysun Sahin, Senem Derya Tatar, Mustafa Yilmaz Gok, Akkan Avci, Sadiye Yolcu Seven
BACKGROUND: Triage refers to classifying and prioritizing patients based on the severity of their injuries or illnesses in the health care setting. The increasing number of elderly patients seeking care in emergency departments (EDs) highlights the need for special attention to the unique needs of this patient population. AIM: We aimed to compare the qSOFA, Emergency Severity Index (ESI), National Early Warning Score (NEWS), and Manchester Triage System (MTS) scores to assist ED physicians in assessing the severity of elderly patients' clinical conditions and triaging them appropriately...
March 14, 2024: Irish Journal of Medical Science
#7
JOURNAL ARTICLE
Yi-Min Wang, I-Min Chiu, Yu-Ping Chuang, Chi-Yung Cheng, Chun-Fu Lin, Fu-Jen Cheng, Chien-Fu Lin, Chao-Jui Li
INTRODUCTION: The objective of this multi-center retrospective cohort study was to devise a predictive tool known as RAPID-ED. This model identifies non-traumatic adult patients at significant risk for cardiac arrest within 48 hours post-admission from the emergency department. METHODS: Data from 224,413 patients admitted through the emergency department (2016-2020) was analyzed, incorporating vital signs, lab tests, and administered therapies. A multivariable regression model was devised to anticipate early cardiac arrest...
March 2024: Resuscitation plus
#8
JOURNAL ARTICLE
Jason M Nagata, Omar M Sajjad, Natalia Smith, Gabriel Zamora, Sanya Dhama, Abubakr A A Al-Shoaibi, Kyle T Ganson, Alexander Testa, Megan A Moreno, Orsolya Kiss, Fiona C Baker, Dylan B Jackson
BACKGROUND: Social media can influence alcohol initiation behaviors such as sipping, which can lead to future adverse alcohol-related outcomes. Few studies have examined the role of problematic social media use, characterized by addiction, mood modification, tolerance, withdrawal, conflict, and relapse, especially in early adolescence. OBJECTIVE: To examine the prospective association between social media use and sipping alcohol in a nationwide sample of early adolescents, and the extent to which problematic social media use mediates the association...
February 9, 2024: Substance Use & Misuse
#9
JOURNAL ARTICLE
Abdullah M Algarni, Musa S Alfaifi, Ali A Al Bshabshe, Othman M Omair, Mohammed A Alsultan, Hasan M Alzahrani, Hadi E Alali, Abdullah A Alsabaani, Ali M Alqarni, Salah A Alghanem, Bandar S Al Mufareh, Ayesha M Almemari, Abdulrahman A Sindi, Ibrahim U Ozturan, Abdullah A Alhadhira, Asaad S Shujaa, Abdullah H Alotaibi, Moosa M Awladthani, Ahmed A Alsaad, Abdullah A Almarshed, AlHanouv M AlQahtani, Tim R Harris, Bader A Alyahya, Saad A Assiri, Feras H Abuzeyad, Sara N Kazim, Abdulrahman A Al-Fares, Faisal Y Almazroua, Naif T Marzook, Abdullah A Basri, Abdallah M Elsafti, Abdulaziz S Alalshaikh, Cansu A Özturan, Yousef I Alawad, Awad AlOmari, Malek A Alkhateeb, Moonis M Farooq, Latifa Ali AlMutairi, Muneera M Alasfour, Mohammad I Al Haber, Umma-Kulthum A Umar, Nidal H Bokhary, Saeed F Alqahtani, Abdulrhman Almutairi, Hisham F Alyahya, Wejdan S Alzahrani, Fawziah Alsalmi, Abdulmajeed M Omair, Faysal M Alasmari, Sultan Y Alfifi, Mohammed S Al-Nujimi, Farid Foroutan
BACKGROUND: Early identification of a patient with infection who may develop sepsis is of utmost importance. Unfortunately, this remains elusive because no single clinical measure or test can reflect complex pathophysiological changes in patients with sepsis. However, multiple clinical and laboratory parameters indicate impending sepsis and organ dysfunction. Screening tools using these parameters can help identify the condition, such as SIRS, quick SOFA (qSOFA), National Early Warning Score (NEWS), or Modified Early Warning Score (MEWS)...
2024: PloS One
#10
JOURNAL ARTICLE
Gaja Zager Kocjan, Andreja Avsec, Tina Kavčič
BACKGROUND: Physical inactivity is one of the most influential and pervasive risk factors for health problems. Therefore, public health experts call for interventions to promote physical activity across the lifespan. This study aimed to examine the role of mental health in physical inactivity and the subsequent role of physical activity in various aspects of physical health. METHODS: Data were collected in the third wave of the European Health Interview Survey (EHIS) in Slovenia...
December 28, 2023: Social Science & Medicine
#11
JOURNAL ARTICLE
Matthew Inada-Kim, Francis P Chmiel, Michael Boniface, Daniel Burns, Helen Pocock, John Black, Charles Deakin
OBJECTIVES: To evaluate oxygen saturation and vital signs measured in the community by emergency medical services (EMS) as clinical markers of COVID-19-positive patient deterioration. DESIGN: A retrospective data analysis. SETTING: Patients were conveyed by EMS to two hospitals in Hampshire, UK, between 1 March 2020 and 31 July 2020. PARTICIPANTS: A total of 1080 patients aged ≥18 years with a COVID-19 diagnosis were conveyed by EMS to the hospital...
January 2, 2024: BMJ Open
#12
JOURNAL ARTICLE
Loai Albinsaad, Mohammed Alessa, Jawaher I Alraihan, Mohammed A Albesher, Haidar A Alessa, Asma Almubarak
Introduction Breast cancer is the leading type of cancer in women globally, contributing significantly to cancer-related deaths. In Saudi Arabia, it ranks as the second most common cancer among women. Studies have highlighted a lack of awareness about breast cancer, negatively impacting breast self-examination practices. The Eastern Province has particularly high incidence rates. Knowledge of risk and protective factors can aid in prevention and early detection. While some studies show good awareness, this research aims to assess women's knowledge and attitudes about breast cancer risk factors and warning signs in the Eastern Province...
November 2023: Curēus
#13
JOURNAL ARTICLE
Karoline Kjærgaard, Jesper Mølgaard, Søren M Rasmussen, Christian Sylvest Meyhoff, Eske Kvanner Aasvang
OBJECTIVES: Continuous vital sign monitoring at the general hospital ward has major potential advantages over intermittent monitoring but generates many alerts with risk of alert fatigue. We hypothesized that the number of alerts would be decreased using different filters. METHODS: This study was an exploratory analysis of the alert reducing effect from adding two different filters to continuously collected vital sign data (peripheral oxygen saturation, blood pressure, heart rate and respiratory rate) in patients admitted after major surgery or severe medical disease...
December 21, 2023: Hospital Practice (Minneapolis)
#14
JOURNAL ARTICLE
David Edholm, Johan Olsson Hofgård, Ellen Andersson, Erik Stenberg, Torsten Olbers
BACKGROUND: Roux-en-Y gastric bypass (RYGB) is one of the most common bariatric procedures. Internal herniation may lead to small bowel ischemia requiring small bowel resection, resulting in short bowel syndrome. OBJECTIVE: To determine the incidence of extensive small bowel resection in patients operated with RYGB. We also aimed to look for early clinical warning signs among patients requiring extensive small bowel resection. SETTING: Cohort from national quality registers...
April 2024: Surgery for Obesity and Related Diseases
#15
JOURNAL ARTICLE
Elliott K Main, Matt Fuller, Vesela P Kovacheva, Rania Elkhateb, Kristen Azar, Morgan Caldwell, Vanna Chiem, Mindy Foster, Ronald Gibbs, Brenna L Hughes, Rebecca Johnson, Nobin Kottukapally, Magdalena Sanz Cortes, Melissa G Rosenstein, Laurence E Shields, Sylvia Sudat, Caitlin D Sutton, Paloma Toledo, Austin Traylor, Kurt Wharton, Melissa E Bauer
OBJECTIVE: To evaluate the screening performance characteristics of existing tools for the diagnosis of sepsis during delivery admissions. METHODS: This was a case-control study using electronic health record data, including vital signs and laboratory results, for all delivery admissions of patients with sepsis from 59 nationally distributed hospitals. Patients with sepsis were matched by gestational age at delivery in a 1:4 ratio with patients without sepsis to create a comparison group...
December 12, 2023: Obstetrics and Gynecology
#16
JOURNAL ARTICLE
Liqing Yang, Yichuan Yu, Wensheng Hou, Xiaoying Wu, Lin Chen
To address the challenges posed by the aging process, we designed and validated an LSTM-based automatic remote health risk assessment system for the elderly. This system consists of a wireless physiological parameter sensing unit, a vital sign prediction unit and a pre-defined risk scoring criteria unit. The vital sign prediction module is composed of five 5-input-1-output neural networks based on the LSTM architecture, which are responsible for predicting the vital signs collected by wireless sensors, including: systolic blood pressure (SBP), pulse rate (PR), respiratory rate (RR), temperature (TEMP), and oxygen saturation (SPO2)...
July 2023: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
#17
JOURNAL ARTICLE
Haitham M Alghamdi, Bsaim A Altirkistani, Rabea A Baatya, Yasir O Marghalani, Nahla M Alshaikh
Background Monitoring children's acquisition of developmental milestones is integral to pediatric practice. Though pediatricians are responsible for evaluating children's development, parents have a crucial role in addressing delays as early as possible, where early detection of developmental delay can help in early intervention and ultimately potentiate a child's cognitive and social abilities toward an independent life. This study assesses parental knowledge of the warning signs denoting delayed developmental milestone acquisition, in addition to analyzing demographic variables that may influence their level of knowledge...
November 2023: Curēus
#18
JOURNAL ARTICLE
Taehwa Kim, Yunwon Tae, Hye Ju Yeo, Jin Ho Jang, Kyungjae Cho, Dongjoon Yoo, Yeha Lee, Sung-Ho Ahn, Younga Kim, Narae Lee, Woo Hyun Cho
BACKGROUND: Successful sepsis treatment depends on early diagnosis. We aimed to develop and validate a system to predict sepsis and septic shock in real time using deep learning. METHODS: Clinical data were retrospectively collected from electronic medical records (EMRs). Data from 2010 to 2019 were used as development data, and data from 2020 to 2021 were used as validation data. The collected EMRs consisted of eight vital signs, 13 laboratory data points, and three demographic information items...
November 17, 2023: Journal of Clinical Medicine
#19
JOURNAL ARTICLE
Connor Price, David Prytherch, Ina Kostakis, Jim Briggs
BACKGROUND: The National Early Warning Score (NEWS) is used in hospitals across the UK to detect deterioration of patients within care pathways. It is used for most patients, but there are relatively few studies validating its performance in groups of patients with specific conditions. METHODS: The performance of NEWS was evaluated against 36 other Early Warning Scores, in 123 patient groups, through use of the area under the receiver operating characteristic (AUROC) curve technique, to compare the abilities of each Early Warning Score to discriminate an outcome within 24hrs of vital sign recording...
November 4, 2023: Resuscitation
#20
JOURNAL ARTICLE
Laura Bacelar de Araujo Lourenço, Mariana de Jesus Meszaros, Michele de Freitas Neves Silva, Thaís Moreira São-João
BACKGROUND: During the hospitalization period, it is possible to observe considerable changes in the vital parameters of patients, which may require emergency interventions or intensive treatment. The alteration of signs and symptoms that lead to physiological instability that can worsen the clinical picture with progression to shock, respiratory failure, or cardiorespiratory arrest is currently defined as clinical deterioration. Identifying signs of clinical deterioration at an early stage can lead to substantial decreases in mortality rates, the need for emergency interventions, and unscheduled treatments in intensive care units...
October 17, 2023: JMIR Research Protocols
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