Read by QxMD icon Read

Hypertrophic cardiomyopathy, athletes heart

James McKinney, Daniel J Lithwick, Barbara N Morrison, Hamed Nazzari, Michael Luong, Christopher B Fordyce, Jack Taunton, Andrew D Krahn, Brett Heilbron, Saul Isserow
BACKGROUND: Sudden cardiac death (SCD) is frequently the first manifestation of underlying cardiovascular disease in young competitive athletes (YCAs), yet there are no Canadian guidelines for preparticipation screening in this population. The goal of this study was to determine the prevalence of potentially lethal cardiovascular disease in a sample of Canadian YCAs by comparing 2 screening strategies. METHODS: We prospectively screened 1419 YCAs in British Columbia, Canada (age 12-35 years)...
June 23, 2016: Canadian Journal of Cardiology
Jonathan A Drezner, David S Owens, Jordan M Prutkin, Jack C Salerno, Kimberly G Harmon, Shelley Prosise, Alana Clark, Irfan M Asif
The most effective protocol for cardiovascular screening of competitive athletes remains highly controversial. This study was a prospective, multicenter trial of cardiovascular screening at 35 National Collegiate Athletic Association institutions. Screening included a standardized history and physical examination (PE) as recommended by the American Heart Association and a 12-lead electrocardiogram (ECG) at rest. Centralized electrocardiographic interpretation was provided using the Seattle criteria. Athletes with screening abnormalities underwent additional evaluation directed by the host institution medical team...
September 1, 2016: American Journal of Cardiology
Asaad A Khan, Lucy Safi, Malissa Wood
Athletic heart syndrome refers to the physiological and morphological changes that occur in a human heart after repetitive strenuous physical exercise. Examples of exercise-induced changes in the heart include increases in heart cavity dimensions, augmentation of cardiac output, and increases in heart muscle mass. These cardiac adaptations vary based on the type of exercise performed and are often referred to as sport-specific cardiac remodeling. The hemodynamic effects of endurance and strength training exercise lead to these adaptations...
April 2016: Methodist DeBakey Cardiovascular Journal
Johanna Kuusisto, Petri Sipola, Pertti Jääskeläinen, Anita Naukkarinen
Hypertrophic cardiomyopathy (HCM) is the most common inherited heart disease, with the prevalence of about 1/500. During the last two decades, the knowledge of the etiology, pathogenesis, risk stratification and prevention of sudden death in HCM has substantially advanced. Most often, HCM is familial and caused by mutations in sarcomere genes, inherited in an autosomal dominant manner. In Finland, genetic background of HCM is unique, with a few founder mutations in cardiac sarcomere genes accounting for a considerable proportion of the disease...
July 27, 2016: Annals of Medicine
Carlos Magalhães-Ribeiro, João Freitas
Syncope is a common but concerning event in young athletes. Although mostly due to benign reflex causes, syncope may be arrhythmic and precede sudden cardiac death. Efforts must therefore be made to distinguish post-exertional syncope from syncope during exercise, which can be an ominous sign of a possible underlying heart disease, such as hypertrophic cardiomyopathy. Prevention requires cooperation between physician and athlete, in order to identify individuals at risk and to protect them from sudden death...
July 2016: Portuguese Journal of Cardiology: An Official Journal of the Portuguese Society of Cardiology
Barry J Maron, Tammy S Haas, Aneesha Ahluwalia, Caleb J Murphy, Ross F Garberich
BACKGROUND: Sudden deaths in young competitive athletes are tragic events, with high public visibility. The importance of race and gender with respect to sport and the diagnosis and causes of sudden death in athletes has generated substantial interest. METHODS: The US National Registry of Sudden Death in Athletes, 1980-2011, was accessed to define the epidemiology and causes of sudden deaths in competitive athletes. A total of 2406 deaths were identified in young athletes aged 19 ± 6 years engaged in 29 diverse sports...
April 1, 2016: American Journal of Medicine
Jennifer E Gilda, Xianyin Lai, Frank A Witzmann, Aldrin V Gomes
Familial hypertrophic cardiomyopathy (FHC) is associated with mild to severe cardiac problems and is the leading cause of sudden death in young people and athletes. Although the genetic basis for FHC is well-established, the molecular mechanisms that ultimately lead to cardiac dysfunction are not well understood. To obtain important insights into the molecular mechanism(s) involved in FHC, hearts from two FHC troponin T models (Ile79Asn [I79N] and Arg278Cys [R278C]) were investigated using label-free proteomics and metabolomics...
June 2016: Molecular & Cellular Proteomics: MCP
Gonzalo Grazioli, Domingo Usín, Emilce Trucco, Maria Sanz, Silvia Montserrat, Bàrbara Vidal, Josep Gutierrez, Ramon Canal, Josep Brugada, Lluis Mont, Marta Sitges
Differential diagnosis of hypertrophic cardiomyopathy (HCM) vs athlete's heart is challenging in individuals with mild-moderate left-ventricular hypertrophy. This study aimed to assess ECG and echocardiographic parameters proposed for the differential diagnosis of HCM. The study included 75 men in three groups: control (n=30), "gray zone" athletes with interventricular septum (IVS) measuring 13-15mm (n=25) and HCM patients with IVS of 13-18mm (n=20). The most significant differences were found in relative septal thickness (RST), calculated as the ratio of 2 x IVS to left ventricle end-diastolic diameter (LV-EDD) (0...
July 2016: Journal of Electrocardiology
Barry J Maron, Tammy S Haas, Emily R Duncanson, Ross F Garberich, Andrew M Baker, Shannon Mackey-Bojack
The issue of sudden death in young athletes and consideration for the most practical and optimal strategy to identify those genetic and/or congenital heart diseases responsible for these tragic events continues to be debated. However, proponents of broad-based and mandatory national preparticipation screening, including with 12-lead electrocardiograms have confined the focus to a relatively small segment of the youthful population who choose to engage in competitive athletic programs at the high school, college, and elite-professional level...
April 15, 2016: American Journal of Cardiology
Aditya J Ullal, Ramy S Abdelfattah, Euan A Ashley, Victor F Froelicher
BACKGROUND: Sudden cardiac death is often linked with hypertrophic cardiomyopathy in young athletes, but with a divergence of study results. We performed a meta-analysis to compare the prevalence of sudden cardiac deaths associated with hypertrophic cardiomyopathy vs sudden cardiac deaths associated with structurally normal hearts. METHODS: A structured search of MEDLINE was conducted for studies published from 1990 through 2014. Retrospective cohort studies, patient registries, and autopsy series examining sudden cardiac death etiology in young individuals (age ≤35 years) were included...
May 2016: American Journal of Medicine
Amir Kreso, Fahir Barakovic, Senad Medjedovic, Amila Halilbasic, Muhamed Klepic
INTRODUCTION: Among long term athletes there is always present hypertrophy of the left ventricle walls as well as increased cardiac mass. These changes are the result of the heart muscle adaptation to load during the years of training, which should not be considered as pathology. In people suffering from hypertrophic cardiomyopathy (HCM), there is also present hypertrophy of the left ventricle walls and increased mass of the heart, but these changes are the result of pathological changes in the heart caused by a genetic predisposition for the development HCM of...
October 2015: Acta Informatica Medica: AIM
Amir Kreso, Fahir Barakovic, Senad Medjedovic, Amela Halilbasic, Muhamed Klepic
INTRODUCTION: "Athlete's heart syndrome" is a condition characterized by structural, electrophysiologic and functional adaptation of the myocardium to physical activity (training), depending on the activity intensity, duration and type. In athletes left ventricular hypertrophy often resembles comorbid conditions (hypertension or hypertrophic cardiomyopathy) so the differential diagnosis of the disease is very important and crucial, especially in people who are in active training. In fact, if an athlete has finding which indicate thickening of the left ventricle walls, should be distinguished hypertrophy which occurred as a result of many years of training from accidental existence of hypertension or hypertrophic cardiomyopathy in the same person...
October 2015: Medical Archives
Barry J Maron, James E Udelson, Robert O Bonow, Rick A Nishimura, Michael J Ackerman, N A Mark Estes, Leslie T Cooper, Mark S Link, Martin S Maron
No abstract text is available yet for this article.
December 1, 2015: Circulation
Irfan M Asif, David E Price, Alex Ewing, Ashwin L Rao, Kimberly G Harmon, Jonathan A Drezner
AIM: To determine the psychological impact of athletes diagnosed with cardiac disease. METHODS AND DESIGN: Athletes diagnosed with cardiovascular disorders were recruited to complete the Impact of Event Scale (IES), a validated tool measuring responses to a traumatic event. IES scoring =0-88 (<12= normal, 12-32=recommend monitoring, >33=significant stress reaction). Subscales include: intrusion, avoidance and hyperarousal. RESULTS: 30 athletes (53% male, 83% Caucasian, median age 18...
February 2016: British Journal of Sports Medicine
Barry J Maron, James E Udelson, Robert O Bonow, Rick A Nishimura, Michael J Ackerman, N A Mark Estes, Leslie T Cooper, Mark S Link, Martin S Maron
No abstract text is available yet for this article.
December 1, 2015: Journal of the American College of Cardiology
Edda Bahlmann, Karl Heinz Kuck, Christoph A Nienaber
Hypertrophic cardiomyopathy (HCM) is a complex genetic disorder usually diagnosed in a young adult population. The diagnosis is based on echocardiographic identification of left ventricular hypertrophy, associated with a non-dilated hyperdynamic chamber in the absence of another cardiac or systemic disorder. The differentiation between HCM and physiological left ventricular hypertrophy (athlete`s heart) is essential: HCM is the main cause of exercise-induced sudden cardiac death in the young and especially in young athletes with overlapping features in Athlete's Heart or HCM...
July 2015: Deutsche Medizinische Wochenschrift
Meagan M Wasfy, Rory B Weiner
PURPOSE OF REVIEW: Exercise-induced cardiac remodeling (EICR), or athlete's heart, refers to the cardiac structural and functional adaptations to exercise training. Although the degree of physiological left ventricular hypertrophy (LVH) is typically mild in trained athletes, in some LVH is substantial enough to prompt concern for hypertrophic cardiomyopathy (HCM). This review summarizes the available imaging tools to help make this important clinical distinction. RECENT FINDINGS: Advanced echocardiographic techniques (tissue and Doppler and speckle tracking) and cardiac magnetic resonance imaging are being investigated to aid in the differentiation of EICR and HCM in 'gray-zone' hypertrophy cases...
September 2015: Current Opinion in Cardiology
Chika Kadota, Takuro Arimura, Takeharu Hayashi, Taeko K Naruse, Sachio Kawai, Akinori Kimura
There is an overlap between the physiological cardiac remodeling associated with training in athletes, the so-called athlete's heart, and mild forms of hypertrophic cardiomyopathy (HCM), the most common hereditary cardiac disease. HCM is often accompanied by unfavorable outcomes including a sudden cardiac death in the adolescents. Because one of the initial signs of HCM is abnormality in electrocardiogram (ECG), athletes may need to monitor for ECG findings to prevent any unfavorable outcomes. HCM is caused by mutations in genes for sarcomere proteins, but there is no report on the systematic screening of gene mutations in athletes...
October 2015: Journal of Human Genetics
Kalie Y Kebed, J Martijn Bos, Nandan S Anavekar, Sharon L Mulvagh, Michael J Ackerman, Steve R Ommen
No abstract text is available yet for this article.
July 2015: Circulation. Cardiovascular Imaging
Karina Wierzbowska-Drabik, Andrzej Marcinkiewicz, Jarosław Damian Kasprzak
Ensuring safety of young athletes and employees who perform hard physical work within the scope of their professional duties, with a special focus on prevention of a sudden cardiac death at sports fields or during hard physical work is one of the most important tasks, which demands joint effort of cardiologists and sport physicians or occupational physicians, who qualify patients for a job or a sport discipline. Apart from hypertrophic and arhythmogenic right ventricular cardiomyopathy, coronary anomalies and aortic dissection belong to the most frequent causes of dramatic complications during competitive exercise or work with an increased energy expenditure...
2015: International Journal of Occupational Medicine and Environmental Health
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"