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Hypertrophic cardiomyopathy, athletes heart

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https://www.readbyqxmd.com/read/28452637/incidence-and-etiology-of-sudden-cardiac-death-new-updates-for-athletic-departments
#1
Irfan M Asif, Kimberly G Harmon
CONTEXT: Sudden cardiac death (SCD) in a young athlete is a tragic event and is the leading medical cause of death in this population. The precise incidence of SCD in young athletes has been subject of debate, with studies reporting drastically different rates (1:917,000 athlete-years (AYs) to 1:3000 AYs) depending on the methodological design of the investigation or the targeted population. EVIDENCE ACQUISITION: A literature search was performed in PubMed using the terms: incidence, sudden cardiac death, sudden death, sudden cardiac arrest, etiology, pathology, registry, athlete, young, children, and adolescents...
May 2017: Sports Health
https://www.readbyqxmd.com/read/28378431/left-ventricular-biomechanics-in-professional-football-players
#2
T G von Lueder, A Hodt, G F Gjerdalen, K Steine
Chronic exercise induces adaptive changes of left ventricular (LV) ejection and filling capacities which may be detected by novel speckle-tracking echocardiography (STE) and tissue Doppler imaging (TDI)-based techniques. A total of 103 consecutive male elite Norwegian soccer players and 46 age-matched healthy controls underwent echocardiography at rest. STE was used to assess LV torsional mechanics and LV systolic longitudinal strain (LS). Diastolic function was evaluated by trans-mitral blood flow, mitral annular velocities by TDI, and LV inflow propagation velocity by color M-mode...
April 4, 2017: Scandinavian Journal of Medicine & Science in Sports
https://www.readbyqxmd.com/read/28281159/utility-of-magnetic-resonance-imaging-in-the-evaluation-of-left-ventricular-thickening
#3
REVIEW
Nicholas Fulton, Prabhakar Rajiah
Left ventricular (LV) thickening can be due to hypertrophy (concentric, asymmetric, eccentric) or remodelling (concentric or asymmetric). Pathological thickening may be caused by pressure overload, volume overload, infiltrative disorders, hypertrophic cardiomyopathy, athlete's heart or neoplastic infiltration. Magnetic resonance imaging (MRI) plays an important role in the comprehensive evaluation of LV thickening, including: establishing diagnosis, determining LV geometry, establishing aetiology, quantification, identifying prognostic factors, serial follow-up and treatment response...
April 2017: Insights Into Imaging
https://www.readbyqxmd.com/read/28220574/selective-use-of-the-electrocardiogram-in-pediatric-preparticipation-athletic-examinations-among-pediatric-primary-care-providers
#4
Bradley C Clark, Joshua M Hayman, Charles I Berul, Kristin M Burns, Jonathan R Kaltman
OBJECTIVES: Recent literature examining insurance administrative data suggests that a selective approach, with concurrent history and physical exam (H&P), for obtaining an electrocardiogram (ECG) as a part of a preparticipation examination (PPE) for pediatric athletes is commonly used in the primary care setting demonstrating a high rate of disease detection. We sought to understand practice patterns of providers with regard to usage of ECG as a part of PPE. METHODS: Utilizing an online survey, we queried primary care providers regarding their practice patterns, rationale, and concerns regarding use of ECGs as a part of the PPE...
February 21, 2017: Annals of Noninvasive Electrocardiology
https://www.readbyqxmd.com/read/28070839/-1-h-and-31-p-myocardial-magnetic-resonance-spectroscopy-in-non-obstructive-hypertrophic-cardiomyopathy-patients-and-competitive-athletes
#5
Francesco Secchi, Giovanni Di Leo, Marcello Petrini, Riccardo Spairani, Marco Alì, Marco Guazzi, Francesco Sardanelli
PURPOSE: The clinical differentiation between athlete's heart and mild forms of non-obstructive hypertrophic cardiomyopathy (HCM) is crucial. We hypothesized that differences do exist between the myocardial metabolism of patients with non-obstructive HCM and competitive athletes (CAs). Our aim was to evaluate myocardial metabolism with (31)P-MRS and (1)H-MRS in HCM patients and CAs. MATERIALS AND METHODS: After Ethics Committee approval, 15 CAs and 7 HCM patients were prospectively enrolled...
April 2017: La Radiologia Medica
https://www.readbyqxmd.com/read/28065914/athlete-s-heart-vs-apical-hypertrophic-cardiomyopathy-look-again
#6
Fatima Samad, Daniel R Harland, Mark Girzadas, M Fuad Jan, A Jamil Tajik
No abstract text is available yet for this article.
March 1, 2017: European Heart Journal Cardiovascular Imaging
https://www.readbyqxmd.com/read/27692657/detecting-underlying-cardiovascular-disease-in-young-competitive-athletes
#7
James McKinney, Daniel J Lithwick, Barbara N Morrison, Hamed Nazzari, Michael Luong, Christopher B Fordyce, Jack Taunton, Andrew D Krahn, Brett Heilbron, Saul Isserow
BACKGROUND: Sudden cardiac death (SCD) is frequently the first manifestation of underlying cardiovascular disease in young competitive athletes (YCAs), yet there are no Canadian guidelines for preparticipation screening in this population. The goal of this study was to determine the prevalence of potentially lethal cardiovascular disease in a sample of Canadian YCAs by comparing 2 screening strategies. METHODS: We prospectively screened 1419 YCAs in British Columbia, Canada (age 12-35 years)...
January 2017: Canadian Journal of Cardiology
https://www.readbyqxmd.com/read/27496294/electrocardiographic-screening-in-national-collegiate-athletic-association-athletes
#8
Jonathan A Drezner, David S Owens, Jordan M Prutkin, Jack C Salerno, Kimberly G Harmon, Shelley Prosise, Alana Clark, Irfan M Asif
The most effective protocol for cardiovascular screening of competitive athletes remains highly controversial. This study was a prospective, multicenter trial of cardiovascular screening at 35 National Collegiate Athletic Association institutions. Screening included a standardized history and physical examination (PE) as recommended by the American Heart Association and a 12-lead electrocardiogram (ECG) at rest. Centralized electrocardiographic interpretation was provided using the Seattle criteria. Athletes with screening abnormalities underwent additional evaluation directed by the host institution medical team...
September 1, 2016: American Journal of Cardiology
https://www.readbyqxmd.com/read/27486490/cardiac-imaging-in-athletes
#9
REVIEW
Asaad A Khan, Lucy Safi, Malissa Wood
Athletic heart syndrome refers to the physiological and morphological changes that occur in a human heart after repetitive strenuous physical exercise. Examples of exercise-induced changes in the heart include increases in heart cavity dimensions, augmentation of cardiac output, and increases in heart muscle mass. These cardiac adaptations vary based on the type of exercise performed and are often referred to as sport-specific cardiac remodeling. The hemodynamic effects of endurance and strength training exercise lead to these adaptations...
April 2016: Methodist DeBakey Cardiovascular Journal
https://www.readbyqxmd.com/read/27460395/current-perspectives-in-hypertrophic-cardiomyopathy-with-the-focus-on-patients-in-the-finnish-population-a-review
#10
Johanna Kuusisto, Petri Sipola, Pertti Jääskeläinen, Anita Naukkarinen
Hypertrophic cardiomyopathy (HCM) is the most common inherited heart disease, with the prevalence of about 1/500. During the last two decades, the knowledge of the etiology, pathogenesis, risk stratification and prevention of sudden death in HCM has substantially advanced. Most often, HCM is familial and caused by mutations in sarcomere genes, inherited in an autosomal dominant manner. In Finland, genetic background of HCM is unique, with a few founder mutations in cardiac sarcomere genes accounting for a considerable proportion of the disease...
November 2016: Annals of Medicine
https://www.readbyqxmd.com/read/27372256/syncope-in-the-young-athlete-assessment-of-prognosis-in-subjects-with-hypertrophic-cardiomyopathy
#11
Carlos Magalhães-Ribeiro, João Freitas
Syncope is a common but concerning event in young athletes. Although mostly due to benign reflex causes, syncope may be arrhythmic and precede sudden cardiac death. Efforts must therefore be made to distinguish post-exertional syncope from syncope during exercise, which can be an ominous sign of a possible underlying heart disease, such as hypertrophic cardiomyopathy. Prevention requires cooperation between physician and athlete, in order to identify individuals at risk and to protect them from sudden death...
July 2016: Portuguese Journal of Cardiology: An Official Journal of the Portuguese Society of Cardiology
https://www.readbyqxmd.com/read/27039955/demographics-and-epidemiology-of-sudden-deaths-in-young-competitive-athletes-from-the-united-states-national-registry
#12
Barry J Maron, Tammy S Haas, Aneesha Ahluwalia, Caleb J Murphy, Ross F Garberich
BACKGROUND: Sudden deaths in young competitive athletes are tragic events, with high public visibility. The importance of race and gender with respect to sport and the diagnosis and causes of sudden death in athletes has generated substantial interest. METHODS: The US National Registry of Sudden Death in Athletes, 1980-2011, was accessed to define the epidemiology and causes of sudden deaths in competitive athletes. A total of 2406 deaths were identified in young athletes aged 19 ± 6 years engaged in 29 diverse sports...
November 2016: American Journal of Medicine
https://www.readbyqxmd.com/read/27022107/delineation-of-molecular-pathways-involved-in-cardiomyopathies-caused-by-troponin-t-mutations
#13
Jennifer E Gilda, Xianyin Lai, Frank A Witzmann, Aldrin V Gomes
Familial hypertrophic cardiomyopathy (FHC) is associated with mild to severe cardiac problems and is the leading cause of sudden death in young people and athletes. Although the genetic basis for FHC is well-established, the molecular mechanisms that ultimately lead to cardiac dysfunction are not well understood. To obtain important insights into the molecular mechanism(s) involved in FHC, hearts from two FHC troponin T models (Ile79Asn [I79N] and Arg278Cys [R278C]) were investigated using label-free proteomics and metabolomics...
June 2016: Molecular & Cellular Proteomics: MCP
https://www.readbyqxmd.com/read/27016258/differentiating-hypertrophic-cardiomyopathy-from-athlete-s-heart-an-electrocardiographic-and-echocardiographic-approach
#14
Gonzalo Grazioli, Domingo Usín, Emilce Trucco, Maria Sanz, Silvia Montserrat, Bàrbara Vidal, Josep Gutierrez, Ramon Canal, Josep Brugada, Lluis Mont, Marta Sitges
Differential diagnosis of hypertrophic cardiomyopathy (HCM) vs athlete's heart is challenging in individuals with mild-moderate left-ventricular hypertrophy. This study aimed to assess ECG and echocardiographic parameters proposed for the differential diagnosis of HCM. The study included 75 men in three groups: control (n=30), "gray zone" athletes with interventricular septum (IVS) measuring 13-15mm (n=25) and HCM patients with IVS of 13-18mm (n=20). The most significant differences were found in relative septal thickness (RST), calculated as the ratio of 2 x IVS to left ventricle end-diastolic diameter (LV-EDD) (0...
July 2016: Journal of Electrocardiology
https://www.readbyqxmd.com/read/26949036/comparison-of-the-frequency-of-sudden-cardiovascular-deaths-in-young-competitive-athletes-versus-nonathletes-should-we-really-screen-only-athletes
#15
MULTICENTER STUDY
Barry J Maron, Tammy S Haas, Emily R Duncanson, Ross F Garberich, Andrew M Baker, Shannon Mackey-Bojack
The issue of sudden death in young athletes and consideration for the most practical and optimal strategy to identify those genetic and/or congenital heart diseases responsible for these tragic events continues to be debated. However, proponents of broad-based and mandatory national preparticipation screening, including with 12-lead electrocardiograms have confined the focus to a relatively small segment of the youthful population who choose to engage in competitive athletic programs at the high school, college, and elite-professional level...
April 15, 2016: American Journal of Cardiology
https://www.readbyqxmd.com/read/26800575/hypertrophic-cardiomyopathy-as-a-cause-of%C3%A2-sudden-cardiac-death-in-the-young-a-meta-analysis
#16
Aditya J Ullal, Ramy S Abdelfattah, Euan A Ashley, Victor F Froelicher
BACKGROUND: Sudden cardiac death is often linked with hypertrophic cardiomyopathy in young athletes, but with a divergence of study results. We performed a meta-analysis to compare the prevalence of sudden cardiac deaths associated with hypertrophic cardiomyopathy vs sudden cardiac deaths associated with structurally normal hearts. METHODS: A structured search of MEDLINE was conducted for studies published from 1990 through 2014. Retrospective cohort studies, patient registries, and autopsy series examining sudden cardiac death etiology in young individuals (age ≤35 years) were included...
May 2016: American Journal of Medicine
https://www.readbyqxmd.com/read/26635434/echocardiography-differences-between-athlete-s-heart-hearth-and-hypertrophic-cardiomyopathy
#17
Amir Kreso, Fahir Barakovic, Senad Medjedovic, Amila Halilbasic, Muhamed Klepic
INTRODUCTION: Among long term athletes there is always present hypertrophy of the left ventricle walls as well as increased cardiac mass. These changes are the result of the heart muscle adaptation to load during the years of training, which should not be considered as pathology. In people suffering from hypertrophic cardiomyopathy (HCM), there is also present hypertrophy of the left ventricle walls and increased mass of the heart, but these changes are the result of pathological changes in the heart caused by a genetic predisposition for the development HCM of...
October 2015: Acta Informatica Medica: AIM
https://www.readbyqxmd.com/read/26622085/electrocardiographic-and-echocardiographic-imaging-of-the-heart-of-athletes-and-patients-with-hypertension
#18
Amir Kreso, Fahir Barakovic, Senad Medjedovic, Amela Halilbasic, Muhamed Klepic
INTRODUCTION: "Athlete's heart syndrome" is a condition characterized by structural, electrophysiologic and functional adaptation of the myocardium to physical activity (training), depending on the activity intensity, duration and type. In athletes left ventricular hypertrophy often resembles comorbid conditions (hypertension or hypertrophic cardiomyopathy) so the differential diagnosis of the disease is very important and crucial, especially in people who are in active training. In fact, if an athlete has finding which indicate thickening of the left ventricle walls, should be distinguished hypertrophy which occurred as a result of many years of training from accidental existence of hypertension or hypertrophic cardiomyopathy in the same person...
October 2015: Medical Archives
https://www.readbyqxmd.com/read/26621644/eligibility-and-disqualification-recommendations-for-competitive-athletes-with-cardiovascular-abnormalities-task-force-3-hypertrophic-cardiomyopathy-arrhythmogenic-right-ventricular-cardiomyopathy-and-other-cardiomyopathies-and-myocarditis-a-scientific-statement
#19
REVIEW
Barry J Maron, James E Udelson, Robert O Bonow, Rick A Nishimura, Michael J Ackerman, N A Mark Estes, Leslie T Cooper, Mark S Link, Martin S Maron
No abstract text is available yet for this article.
December 1, 2015: Circulation
https://www.readbyqxmd.com/read/26612845/the-impact-of-diagnosis-measuring-the-psychological-response-to-being-diagnosed-with-serious-or-potentially-lethal-cardiac-disease-in-young-competitive-athletes
#20
Irfan M Asif, David E Price, Alex Ewing, Ashwin L Rao, Kimberly G Harmon, Jonathan A Drezner
AIM: To determine the psychological impact of athletes diagnosed with cardiac disease. METHODS AND DESIGN: Athletes diagnosed with cardiovascular disorders were recruited to complete the Impact of Event Scale (IES), a validated tool measuring responses to a traumatic event. IES scoring =0-88 (<12= normal, 12-32=recommend monitoring, >33=significant stress reaction). Subscales include: intrusion, avoidance and hyperarousal. RESULTS: 30 athletes (53% male, 83% Caucasian, median age 18...
February 2016: British Journal of Sports Medicine
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