Filip Mivalt, Vaclav Kremen, Vladimir Sladky, Jie Cui, Nicholas Gregg, Irena Balzekas, Victoria Marks, Erik K St Louis, Paul E Croarkin, Brian Nils Lundstrom, Noelle Nelson, Jiwon Kim, Dora Hermes, Steven Messina, Samuel Worrell, Thomas J Richner, Benjamin H Brinkmann, Timothy Denison, Kai J Miller, Jamie Van Gompel, Matt Stead, Gregory A Worrell
The impedance is a fundamental electrical property of brain tissue, playing a crucial role in shaping the characteristics of local field potentials, the extent of ephaptic coupling, and the volume of tissue activated by externally applied electrical brain stimulation. We tracked brain impedance, sleep-wake behavioral state, and epileptiform activity in five people with epilepsy living in their natural environment using an investigational device. The study identified impedance oscillations that span hours to weeks in the amygdala, hippocampus, and anterior nucleus thalamus...
August 18, 2023: Journal of Neuroscience