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https://www.readbyqxmd.com/read/29132369/impact-of-pharmacist-led-medication-management-in-care-transitions
#1
Seungwon Yang
BACKGROUND: When patients are discharged from hospital to home, it is a highlighted vulnerable period for which medication - related problems are prevalent. Researchers have proposed a telephone follow-up intervention as a means to reduce hospital readmissions. However, the outcome of the intervention with the engagement of pharmacists in managing patients' medicines after discharge has not been well explored. The objectives of this study were (1) to determine whether a pharmacist telephone follow-up intervention focusing on patients' medicines management support is associated with a reduction in 30-day readmission rates and (2) to describe the number and types of pharmacist interventions in care transitions...
November 13, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/29128759/a-conduction-velocity-adapted-eikonal-model-for-electrophysiology-problems-with-re-excitability-evaluation
#2
Cesare Corrado, Nejib Zemzemi
Computational models of heart electrophysiology achieved a considerable interest in the medical community as they represent a novel framework for the study of the mechanisms underpinning heart pathologies. The high demand of computational resources and the long computational time required to evaluate the model solution hamper the use of detailed computational models in clinical applications. In this paper, we present a multi-front eikonal algorithm that adapts the conduction velocity (CV) to the activation frequency of the tissue substrate...
November 3, 2017: Medical Image Analysis
https://www.readbyqxmd.com/read/29125413/a-computational-fluid-dynamics-simulation-framework-for-ventricular-catheter-design-optimization
#3
Sofy H Weisenberg, Stephanie C TerMaath, Charlotte N Barbier, Judith C Hill, James A Killeffer
OBJECTIVE Cerebrospinal fluid (CSF) shunts are the primary treatment for patients suffering from hydrocephalus. While proven effective in symptom relief, these shunt systems are plagued by high failure rates and often require repeated revision surgeries to replace malfunctioning components. One of the leading causes of CSF shunt failure is obstruction of the ventricular catheter by aggregations of cells, proteins, blood clots, or fronds of choroid plexus that occlude the catheter's small inlet holes or even the full internal catheter lumen...
November 10, 2017: Journal of Neurosurgery
https://www.readbyqxmd.com/read/29125007/the-importance-of-design-thinking-in-medical-education
#4
Basil Badwan, Roshit Bothara, Mieke Latijnhouwers, Alisdair Smithies, John Sandars
Design thinking provides a creative and innovate approach to solve a complex problem. The discover, define, develop and delivery phases of design thinking lead to the most effective solution and this approach can be widely applied in medical education, from technology intervention projects to curriculum development. Participants in design thinking acquire essential transferable life-long learning skills in dealing with uncertainty and collaborative team working.
November 10, 2017: Medical Teacher
https://www.readbyqxmd.com/read/29123397/highly-sensitive-protein-detection-via-covalently-linked-aptamer-to-mos2-and-exonuclease-assisted-amplification-strategy
#5
Li Gao, Qin Li, Zebin Deng, Brendan Brady, Ni Xia, Yang Zhou, Haixia Shi
Molybdenum disulfide (MoS2) has shown highly attractive superiority as a platform for sensing. However, DNA physisorption on the surface of MoS2 was susceptible to nonspecific probe displacement and false-positive signals. To solve these problems, we have developed a novel MoS2-aptamer nanosheet biosensor for detecting thrombin using a covalently linked aptamer to the MoS2 nanosheet. Ten percent Tween 80 was used to prevent thrombin from nonspecific binding and to rapidly form thiol-DNA/gold nanoparticle (AuNP) conjugates...
2017: International Journal of Nanomedicine
https://www.readbyqxmd.com/read/29121051/process-evaluation-of-knowledge-transfer-across-industries-leveraging-coca-cola-s-supply-chain-expertise-for-medicine-availability-in-tanzania
#6
Erika Linnander, Christina T Yuan, Shirin Ahmed, Emily Cherlin, Kristina Talbert-Slagle, Leslie A Curry
Persistent gaps in the availability of essential medicines have slowed the achievement of global health targets. Despite the supply chain knowledge and expertise that ministries of health might glean from other industries, limited empirical research has examined the process of knowledge transfer from other industries into global public health. We examined a partnership designed to improve the availability of medical supplies in Tanzania by transferring knowledge from The Coca-Cola system to Tanzania's Medical Stores Department (MSD)...
2017: PloS One
https://www.readbyqxmd.com/read/29118963/leveraging-multiactions-to-improve-medical-personalized-ranking-for-collaborative-filtering
#7
Shan Gao, Guibing Guo, Runzhi Li, Zongmin Wang
Nowadays, providing high-quality recommendation services to users is an essential component in web applications, including shopping, making friends, and healthcare. This can be regarded either as a problem of estimating users' preference by exploiting explicit feedbacks (numerical ratings), or as a problem of collaborative ranking with implicit feedback (e.g., purchases, views, and clicks). Previous works for solving this issue include pointwise regression methods and pairwise ranking methods. The emerging healthcare websites and online medical databases impose a new challenge for medical service recommendation...
2017: Journal of Healthcare Engineering
https://www.readbyqxmd.com/read/29118081/perceptions-of-dental-hygienists-and-dentists-about-preventing-early-childhood-caries-a-qualitative-study
#8
Alice M Horowitz, Dushanka V Kleinman, Wendy Child, Sarah D Radice, Catherine Maybury
Purpose: The objective of this qualitative pilot study was to gain an in-depth understanding of dental hygienists and dentists perspectives regarding children's oral health and what needs to be done to prevent early childhood caries (ECC), the most frequent chronic disease of childhood.Methods: A skilled facilitator conducted four focus groups and four phone interviews with 20 dental hygienists and 17 dentists practicing in a variety of locations within the state of Maryland. The interview guide was based on results from previous state-wide surveys of dental hygienists and dentists...
August 2017: Journal of Dental Hygiene: JDH
https://www.readbyqxmd.com/read/29117913/two-interventions-for-patients-with-major-depression-and-severe-chronic-obstructive-pulmonary-disease-impact-on-dyspnea-related-disability
#9
George S Alexopoulos, Jo Anne Sirey, Samprit Banerjee, Danielle S Jackson, Dimitris N Kiosses, Cristina Pollari, Richard S Novitch, Amanda Artis, Patrick J Raue
OBJECTIVE: The Personalized Intervention for Depressed Patients with Chronic Obstructive Pulmonary Disease (PID-C) is an intervention aiming to help patients adhere to their rehabilitation and care. This study tested the hypothesis that the Problem-Solving Adherence (PSA) intervention, which integrates problem-solving into adherence enhancement procedures, reduces dyspnea-related disability more than PID-C. Exploratory analyses sought to identify patients with distinct dyspnea-related disability trajectories and to compare their clinical profiles...
October 10, 2017: American Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/29110557/post-discharge-issues-identified-by-a-call-back-program-identifying-improvement-opportunities
#10
Patty Ines Ojeda, Areeba Kara
OBJECTIVES: The period following discharge from the hospital is one of heightened vulnerability. Discharge instructions serve as a guide during this transition. Yet, clinicians receive little feedback on the quality of this document that ties into the patients' experience. We reviewed the issues voiced by discharged patients via a call-back program and compared them to the discharge instructions they had received. METHODS: At our institution, patients receive an automated call forty-eight hours following discharge inquiring about progress...
November 7, 2017: Hospital Practice (Minneapolis)
https://www.readbyqxmd.com/read/29107144/osteon-myospalacem-baileyi-attenuates-osteoclast-differentiation-through-rankl-induced-nfat-pathways
#11
Yulei Cui, Xiaoying Zhao, Lijuan Mei, Jinjin Pei, Shuo Wang, Yun Shao, Yanduo Tao, Xiaoling Zhang, Lei Jiang
ETHNOPHARMACOLOGICAL RELEVANCE: Osteon Myospalacem Baileyi, known as Sai long gu (Tibetan language, means "blind rat bone"), is the whole skeleton of Tibet plateau rodentia animal Myospalacem Baileyi. Osteon Myospalacem Baileyi had been widely used in the Tibet region as an anti-osteoporosis drug and since 1991 Osteon Myospalacem Baileyi has been listed in the Pharmacopoeia of People's Republic of China as the first-class animal new medical material. However, the mechanism of its anti-osteoporosis activities is still unclear...
October 26, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/29101071/subarachnoid-to-subarachnoid-shunt-for-correction-of-nonfunctioning-baclofen-pump-in-a-severe-case-of-chronic-debilitating-post-spinal-cord-injury-spasticity
#12
Adewale A Bakare, Jonathan Weyhenmeyer, Albert Lee
BACKGROUND AND IMPORTANCE: Perhaps the most disabling condition seen in patients with spinal cord injury is spasticity. Spasticity is characterized as hyperreflexia and hypertonicity as a result of damage to the supraspinal tracts in the aftermath of SCI. Intrathecal baclofen (ITB) is the mainstay therapy for spasticity unresponsive to oral baclofen. One of the problems associated with post-SCI spasticity unresponsive to ITB is development of scar tissue that prevents the diffusion of baclofen in the desired spinal cord area...
October 31, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/29100200/-keeping-on-track-hospital-nurses-struggles-with-maintaining-workflow-while-seeking-to-integrate-evidence-based-practice-into-their-daily-work-a-grounded-theory-study
#13
Åste Renolen, Sevald Høye, Esther Hjälmhult, Lars Johan Danbolt, Marit Kirkevold
BACKGROUND: Evidence-based practice is considered a foundation for the provision of quality care and one way to integrate scientific knowledge into clinical problem-solving. Despite the extensive amount of research that has been conducted to evaluate evidence-based practice implementation and research utilization, these practices have not been sufficiently incorporated into nursing practice. Thus, additional research regarding the challenges clinical nurses face when integrating evidence-based practice into their daily work and the manner in which these challenges are approached is needed...
September 12, 2017: International Journal of Nursing Studies
https://www.readbyqxmd.com/read/29092735/potentially-inappropriate-prescribing-of-drugs-in-elderly-patients-on-chronic-hemodialysis-treatment%C3%A2
#14
Gorana Nedin Ranković, Slobodan M Janković, Radmila Veličković Radovanović, Zorica Jović, Gordana Pešić, Svetlana Pavlović, Branislava Ranković, Jasmina Ranković, Dragana Stokanović, Dane Krtinić
PURPOSE: The aim of this study was to determine the prevalence of potentially inappropriate drug prescription (PIP) in older patients who were on chronic hemodialysis treatment and to explore the factors that lead to PIP. MATERIALS AND METHODS: The study was performed at the Department of Nephrology, Clinical Center Niš, Serbia. It included patients who were 65 years old and older who suffered from the end-stage of kidney failure and were treated by hemodialysis...
October 26, 2017: Clinical Nephrology
https://www.readbyqxmd.com/read/29090296/recent-advances-in-droplet-wetting-and-evaporation
#15
REVIEW
D Brutin, V Starov
The wetting of solid surfaces using liquid droplets has been studied since the early 1800s. Thomas Young and Pierre-Simon Laplace investigated the wetting properties, as well as the role of the contact angle and the coupling of a liquid and solid, on the contact angle formation. The geometry of a sessile droplet is relatively simple. However, it is sufficiently complex to be applied for solving and prediction of real-life situations (for example, metallic inks for inkjet printing, the spreading of pesticides on leaves, the dropping of whole blood, the spreading of blood serum, and drying for medical applications)...
November 1, 2017: Chemical Society Reviews
https://www.readbyqxmd.com/read/29089288/ranking-medical-terms-to-support-expansion-of-lay-language-resources-for-patient-comprehension-of-electronic-health-record-notes-adapted-distant-supervision-approach
#16
Jinying Chen, Abhyuday N Jagannatha, Samah J Fodeh, Hong Yu
BACKGROUND: Medical terms are a major obstacle for patients to comprehend their electronic health record (EHR) notes. Clinical natural language processing (NLP) systems that link EHR terms to lay terms or definitions allow patients to easily access helpful information when reading through their EHR notes, and have shown to improve patient EHR comprehension. However, high-quality lay language resources for EHR terms are very limited in the public domain. Because expanding and curating such a resource is a costly process, it is beneficial and even necessary to identify terms important for patient EHR comprehension first...
October 31, 2017: JMIR Medical Informatics
https://www.readbyqxmd.com/read/29082712/-explore-and-analyze-influence-factors-of-quality-control-on-traditional-chinese-medicine-preparation
#17
Ying Liu, Liang Feng, Xiao-Bin Jia
Chinese medicine preparations are dosage forms made from Chinese herbs as raw materials for medical treatment or prevention. From the active pharmaceutical ingredients to the finished products, every link can affect the quality of Chinese medicine preparations. In recent years, reports about adverse reactions of traditional Chinese medicine preparations have been increasing, so their quality and security problems are increasingly prominent. To solve these problems, the authors in this paper would elucidate the necessity and urgency of quality control from the various influence factors of the Chinese medicine preparations by analyzing how these factors affect the quality, and this could provide the reference for developing the "safe, effective and controllable" modernized Chinese medicine...
May 2017: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/29080200/pivotal-factors-concerned-in-design-of-acupuncture-clinical-research-from-two-articles-in-jama
#18
Jia-Ni Wu, Zong-Shi Qin, Zhi-Shun Liu
Two randomized controlled trials of acupuncture concerning polycystic ovary syndrome (PCOS) and stress urinary incontinence (SUI) were published simultaneously in the 24th issue, 2017 of The Journal of the American Medical Association (JAMA). A trial involving PCOS indicated that active acupuncture did not increase live birth compared with sham acupuncture; meanwhile, another trial referring to SUI showed that electroacupuncture resulted in less urine leakage compared with sham electroacupuncture. With an eye to the negative and positive results of acupuncture, three pivotal factors should be contemplated: (1) proper illness for acupuncture, that is, a problem need to be solved in current medical science, and acupuncture may really work for it; (2) proper pre-studied primary outcome, which is better be objective and repeatedly measurable to reveal the therapeutic effect of acupuncture truly and objectively; (3) proper sham control, which can blind the patients to the upmost extent with minimal biological effects...
November 2017: Chinese Journal of Integrative Medicine
https://www.readbyqxmd.com/read/29073793/infertility-and-surrogacy-first-mentioned-on-a-4000-year-old-assyrian-clay-tablet-of-marriage-contract-in-turkey
#19
Ahmet Berkiz Turp, Ismail Guler, Nuray Bozkurt, Aysel Uysal, Bulent Yilmaz, Mustafa Demir, Onur Karabacak
Mankind has been expressing the breeding topic for thousands of years. Reproduction is the primary instinct of human beings and it is a social, cultural, medical issue. Demographic infertility is one of them, which is defined infertility as the inability to become pregnant with a live birth, within five years of regular sexual contact based upon a consistent union status in marriage maintaining a desire for a child with the lack of contraceptive use and non-lactating. A first mentions about infertility and surrogacy is discovered on a 4000-year-old clay tablet of marriage contract belonging to the Assyrian period exhibited at Istanbul Archeology Museum in Turkey...
October 26, 2017: Gynecological Endocrinology
https://www.readbyqxmd.com/read/29067834/mindfulness-instruction-for-hiv-infected-youth-a-randomized-controlled-trial
#20
Lindsey Webb, Carisa Perry-Parrish, Jonathan Ellen, Erica Sibinga
HIV-infected youth experience many stressors, including stress related to their illness, which can negatively impact their mental and physical health. Therefore, there is a significant need to identify potentially effective interventions to improve stress management, coping, and self-regulation. The object of the study was to assess the effect of a mindfulness-based stress reduction (MBSR) program compared to an active control group on psychological symptoms and HIV disease management in youth utilizing a randomized controlled trial...
October 25, 2017: AIDS Care
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