keyword
MENU ▼
Read by QxMD icon Read
search

Medical problem solving

keyword
https://www.readbyqxmd.com/read/28428048/multi-center-machine-learning-in-imaging-psychiatry-a-meta-model-approach
#1
Petr Dluhoš, Daniel Schwarz, Wiepke Cahn, Neeltje van Haren, René Kahn, Filip Španiel, Jiří Horáček, Tomáš Kašpárek, Hugo Schnack
One of the biggest problems in automated diagnosis of psychiatric disorders from medical images is the lack of sufficiently large samples for training. Sample size is especially important in the case of highly heterogeneous disorders such as schizophrenia, where machine learning models built on relatively low numbers of subjects may suffer from poor generalizability. Via multicenter studies and consortium initiatives researchers have tried to solve this problem by combining data sets from multiple sites. The necessary sharing of (raw) data is, however, often hindered by legal and ethical issues...
April 17, 2017: NeuroImage
https://www.readbyqxmd.com/read/28427314/capturing-complexity-in-pulmonary-system-modelling
#2
Alys R Clark, Haribalan Kumar, Kelly Burrowes
Respiratory disease is a significant problem worldwide, and it is a problem with increasing prevalence. Pathology in the upper airways and lung is very difficult to diagnose and treat, as response to disease is often heterogeneous across patients. Computational models have long been used to help understand respiratory function, and these models have evolved alongside increases in the resolution of medical imaging and increased capability of functional imaging, advances in biological knowledge, mathematical techniques and computational power...
May 2017: Proceedings of the Institution of Mechanical Engineers. Part H, Journal of Engineering in Medicine
https://www.readbyqxmd.com/read/28424378/-recognition-care-and-prevention-of-suicidal-behaviour-in-adults
#3
Zoltán Rihmer, Attila Németh, Tamás Kurimay, Dóra Perczel-Forintos, György Purebl, Péter Döme
Suicide is a major public health problem everywhere in the world and in the WHO European Region suicide accounts for over 120,000 deaths per year. 1. Recognition and diagnosis: An underlying psychiatric disorder is present in up to 90% of people who completed suicide. Comorbidity with depression, anxiety, substance abuse and personality disorders is high. In order to achieve successful prevention of suicidality, adequate diagnostic procedures and appropriate treatment for the underlying disorder are essential...
2017: Psychiatria Hungarica: A Magyar Pszichiátriai Társaság Tudományos Folyóirata
https://www.readbyqxmd.com/read/28423982/from-data-to-improved-decisions-operations-research-in-healthcare-delivery
#4
Muge Capan, Anahita Khojandi, Brian T Denton, Kimberly D Williams, Turgay Ayer, Jagpreet Chhatwal, Murat Kurt, Jennifer Mason Lobo, Mark S Roberts, Greg Zaric, Shengfan Zhang, J Sanford Schwartz
BACKGROUND: The Operations Research Interest Group (ORIG) within the Society of Medical Decision Making (SMDM) is a multidisciplinary interest group of professionals that specializes in taking an analytical approach to medical decision making and healthcare delivery. ORIG is interested in leveraging mathematical methods associated with the field of Operations Research (OR) to obtain data-driven solutions to complex healthcare problems and encourage collaborations across disciplines. This paper introduces OR for the non-expert and draws attention to opportunities where OR can be utilized to facilitate solutions to healthcare problems...
April 1, 2017: Medical Decision Making: An International Journal of the Society for Medical Decision Making
https://www.readbyqxmd.com/read/28423764/an-automatic-approach-for-analyzing-treatment-effectiveness-based-on-medication-hierarchy-the-myocardial-infarction-case-study
#5
Yingxue Li, Yiying Hu, Jingang Yang, Xiang Li, Haifeng Liu, Guotong Xie, Meilin Xu, Jingyi Hu, Yuejin Yang
Treatment effectiveness plays a fundamental role in patient therapies. In most observational studies, researchers often design an analysis pipeline for a specific treatment based on the study cohort. To evaluate other treatments in the data set, much repeated and multifarious work including cohort construction, statistical analysis need to be done. In addition, as treatments are often with an intrinsic hierarchical relationship, many rational comparable treatment pairs can be derived as new treatment variables besides the original single treatment one from the original cohort data set...
2017: Studies in Health Technology and Informatics
https://www.readbyqxmd.com/read/28422894/impact-of-telephone-based-problem-solving-treatment-on-the-use-of-medical-and-psychological-services-in-the-military
#6
John S Richardson, Jesse R Fann, Kathleen R Bell, Nancy Temkin
OBJECTIVE: To explore the impact of problem-solving treatment (PST) for mild traumatic brain injury in active duty service members on the use of medical and psychological services. PARTICIPANTS: Service members who had a mild traumatic brain injury during their last deployment and enrolled in the CONcussion Treatment After Combat Trauma (CONTACT) study. DESIGN: Secondary analysis of a randomized clinical trial. Participants were assigned to telephone-based PST, or e-mailed or mailed education only over the course of 6 months...
April 18, 2017: Journal of Head Trauma Rehabilitation
https://www.readbyqxmd.com/read/28417921/bioethics-of-clinical-applications-of-stem-cells
#7
Carlo Petrini
The clinical applications of stem cells pose a multitude of problems, including safety, efficacy, information and consent, the right to unproven treatments, the "right to try", costs, access, sustainability, scientific scrupulousness, patents and regulatory aspects, to name but a few. This article does not address individual issues, but rather introduces and discusses some of the possible approaches to solving the problems. The first part compares the consequentialist and deontological approaches, offering an overview of "top-down" and "bottom-up" models and proposing the principles of personalism as applied in clinical settings...
April 12, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28408759/reliably-estimating-prevalences-of-atopic-children-an-epidemiological-study-in-an-extensive-and-representative-primary-care-database
#8
David H J Pols, Mark M J Nielen, Joke C Korevaar, Patrick J E Bindels, Arthur M Bohnen
Electronic health records stored in primary care databases might be a valuable source to study the epidemiology of atopic disorders and their impact on health-care systems and costs. However, the prevalence of atopic disorders in such databases varies considerably and needs to be addressed. For this study, all children aged 0-18 years listed in a representative primary care database in the period 2002-2014, with sufficient data quality, were selected. The effects of four different strategies on the prevalences of atopic disorders were examined: (1) the first strategy examined the diagnosis as recorded in the electronic health records, whereas the (2) second used additional requirements (i...
April 13, 2017: NPJ Primary Care Respiratory Medicine
https://www.readbyqxmd.com/read/28401735/training-of-direct-ophthalmoscopy-using-models
#9
Thiago Gs Martins, Ana Luiza Fa Costa, Otaviano Helene, Ricardo V Martins, Andre F Helene, Paulo Schor
BACKGROUND: The time spent on ophthalmology training in medical schools has reduced over the last decades, and the number of doctors unable to solve the most basic ophthalmic problems has increased. METHODS: We conducted a questionnaire with non-ophthalmologist doctors in order to assess the confidence level of their direct ophthalmoscopy examination. This test is very important for the diagnosis of diseases that could lead to blindness, and should be learned by all medical students...
April 12, 2017: Clinical Teacher
https://www.readbyqxmd.com/read/28392673/-life-steps-for-prep-adherence-demonstration-of-a-cbt-based-intervention-to-increase-adherence-to-preexposure-prophylaxis-prep-medication-among-sexual-minority-men-at-high-risk-for-hiv-acquisition
#10
S Wade Taylor, Christina Psaros, David W Pantalone, Jake Tinsley, Steven A Elsesser, Kenneth H Mayer, Steven A Safren
One dramatic advance in human immunodeficiency virus (HIV) prevention efforts has been the prescription of medications typically used for HIV treatment as prophylaxis against acquiring HIV. As a preventative agent, this practice is referred to as "preexposure prophylaxis" (PrEP). The U.S. Federal Drug Administration approved daily PrEP for adults at risk for HIV who do not consistently use condoms during sex with HIV-infected or unknown-status partners. In this paper, we describe a cognitive-behavioral therapy (CBT) PrEP adherence intervention developed for use in high-risk sexual-minority men in the United States, adapted from "Life-Steps," an evidence-based CBT intervention to promote adherence to HIV treatment...
February 2017: Cognitive and Behavioral Practice
https://www.readbyqxmd.com/read/28392460/mesoporous-hydroxyapatite-as-a-carrier-of-olanzapine-for-long-acting-antidepression-treatment-in-rats-with-induced-depression
#11
Yan-Jye Shyong, Mao-Hsien Wang, Li-Wei Kuo, Chang-Fu Su, Wei-Ting Kuo, Kuo-Chi Chang, Feng-Huei Lin
An antidepressant carrier, mesoporous hydroxyapatite olanzapine (mesoHAP-OLZ), was designed to maintain 3weeks of constant medication release. The carrier was intramuscularly (IM) injected, where cellular activity played a role in achieving the goal of constant release. The efficiency of the treatment was evaluated from 3 perspectives in in vivo studies: locomotor activities, biomarkers, and learning and memory ability. MesoHAP-OLZ can increase the locomotor activity in rats with induced depression determined by open field test (OFT) and forced swim test (FST)...
April 6, 2017: Journal of Controlled Release: Official Journal of the Controlled Release Society
https://www.readbyqxmd.com/read/28388623/fzuimagereg-a-toolbox-for-medical-image-registration-and-dose-fusion-in-cervical-cancer-radiotherapy
#12
Qinquan Gao, Shaohui Lin, Penggang Bai, Min Du, Xiaolei Ni, Dongzhong Ke, Tong Tong
The combination external-beam radiotherapy and high-dose-rate brachytherapy is a standard form of treatment for patients with locally advanced uterine cervical cancer. Personalized radiotherapy in cervical cancer requires efficient and accurate dose planning and assessment across these types of treatment. To achieve radiation dose assessment, accurate mapping of the dose distribution from HDR-BT onto EBRT is extremely important. However, few systems can achieve robust dose fusion and determine the accumulated dose distribution during the entire course of treatment...
2017: PloS One
https://www.readbyqxmd.com/read/28384612/a-review-on-thermal-and-catalytic-pyrolysis-of-plastic-solid-waste-psw
#13
REVIEW
S M Al-Salem, A Antelava, A Constantinou, G Manos, A Dutta
Plastic plays an important role in our daily lives due to its versatility, light weight and low production cost. Plastics became essential in many sectors such as construction, medical, engineering applications, automotive, aerospace, etc. In addition, economic growth and development also increased our demand and dependency on plastics which leads to its accumulation in landfills imposing risk on human health, animals and cause environmental pollution problems such as ground water contamination, sanitary related issues, etc...
April 3, 2017: Journal of Environmental Management
https://www.readbyqxmd.com/read/28384167/facing-the-challenges-in-ophthalmology-clerkship-teaching-is-flipped-classroom-the-answer
#14
Ying Lin, Yi Zhu, Chuan Chen, Wei Wang, Tingting Chen, Tao Li, Yonghao Li, Bingqian Liu, Yu Lian, Lin Lu, Yuxian Zou, Yizhi Liu
Recent reform of medical education highlights the growing concerns about the capability of the current educational model to equip medical school students with essential skills for future career development. In the field of ophthalmology, although many attempts have been made to address the problem of the decreasing teaching time and the increasing load of course content, a growing body of literature indicates the need to reform the current ophthalmology teaching strategies. Flipped classroom is a new pedagogical model in which students develop a basic understanding of the course materials before class, and use in-class time for learner-centered activities, such as group discussion and presentation...
2017: PloS One
https://www.readbyqxmd.com/read/28382858/new-japanese-regulatory-frameworks-for-clinical-research-and-marketing-authorization-of-gene-therapy-and-cellular-therapy-products
#15
Sumimasa Nagai, Keiya Ozawa
In Japan, the Pharmaceuticals and Medical Devices Law was passed in 2014. In this new law, regenerative medical products were defined, and a conditional and term-limited approval system only for regenerative medical products was instituted. Gene therapy and adoptive cellular therapy are categorized as regenerative medical products. This law is intended for registration trials for marketing authorization. The Act on the Safety of Regenerative Medicine was also implemented in 2014. This act is intended for clinical research and medical practice involving processed cells other than registration trials...
April 6, 2017: Current Gene Therapy
https://www.readbyqxmd.com/read/28379168/a-novel-medical-e-nose-signal-analysis-system
#16
Lu Kou, David Zhang, Dongxu Liu
It has been proven that certain biomarkers in people's breath have a relationship with diseases and blood glucose levels (BGLs). As a result, it is possible to detect diseases and predict BGLs by analysis of breath samples captured by e-noses. In this paper, a novel optimized medical e-nose system specified for disease diagnosis and BGL prediction is proposed. A large-scale breath dataset has been collected using the proposed system. Experiments have been organized on the collected dataset and the experimental results have shown that the proposed system can well solve the problems of existing systems...
April 5, 2017: Sensors
https://www.readbyqxmd.com/read/28369096/an-improved-chaotic-fruit-fly-optimization-based-on-a-mutation-strategy-for-simultaneous-feature-selection-and-parameter-optimization-for-svm-and-its-applications
#17
Fei Ye, Xin Yuan Lou, Lin Fu Sun
This paper proposes a new support vector machine (SVM) optimization scheme based on an improved chaotic fly optimization algorithm (FOA) with a mutation strategy to simultaneously perform parameter setting turning for the SVM and feature selection. In the improved FOA, the chaotic particle initializes the fruit fly swarm location and replaces the expression of distance for the fruit fly to find the food source. However, the proposed mutation strategy uses two distinct generative mechanisms for new food sources at the osphresis phase, allowing the algorithm procedure to search for the optimal solution in both the whole solution space and within the local solution space containing the fruit fly swarm location...
2017: PloS One
https://www.readbyqxmd.com/read/28369063/tablet-computer-enhanced-training-improves-internal-medicine-exam-performance
#18
Daniel C Baumgart, Ilja Wende, Ulrike Grittner
BACKGROUND: Traditional teaching concepts in medical education do not take full advantage of current information technology. We aimed to objectively determine the impact of Tablet PC enhanced training on learning experience and MKSAP® (medical knowledge self-assessment program) exam performance. METHODS: In this single center, prospective, controlled study final year medical students and medical residents doing an inpatient service rotation were alternatingly assigned to either the active test (Tablet PC with custom multimedia education software package) or traditional education (control) group, respectively...
2017: PloS One
https://www.readbyqxmd.com/read/28368829/immunological-approach-for-full-nurbs-reconstruction-of-outline-curves-from-noisy-data-points-in-medical-imaging
#19
Andres Iglesias, Akemi Galvez, Andreina Avila
Curve reconstruction from data points is an important issue for advanced medical imaging techniques, such as computer tomography (CT) and magnetic resonance imaging (MRI). The most powerful fitting functions for this purpose are the NURBS (non-uniform rational B-splines). Solving the general reconstruction problem with NURBS requires to compute all free variables of the problem (data parameters, breakpoints, control points and their weights). This leads to a very difficult non-convex, nonlinear, high-dimensional, multimodal, continuous optimization problem...
March 28, 2017: IEEE/ACM Transactions on Computational Biology and Bioinformatics
https://www.readbyqxmd.com/read/28364024/angiotensin-ii-peptide-vaccine-protects-ischemic-brain-through-reducing-oxidative-stress
#20
Kouji Wakayama, Munehisa Shimamura, Jun-Ichi Suzuki, Ryo Watanabe, Hiroshi Koriyama, Hiroshi Akazawa, Hironori Nakagami, Hideki Mochizuki, Mitsuaki Isobe, Ryuichi Morishita
BACKGROUND AND PURPOSE: Medication nonadherence is one of major risk factors for the poor outcome in ischemic stroke. Vaccination is expected to solve such a problem because of its long-lasting effects, but its effect on ischemic brain damage is still unknown. Here, we focused on vaccination for renin-angiotensin system and examined the effects of angiotensin II (Ang II) peptide vaccine in permanent middle cerebral artery occlusion model in rats. METHODS: Male Wistar rats were exposed to permanent middle cerebral artery occlusion after 3× injections of Ang II peptide vaccine, and the serum or brain level of anti-Ang II antibody was examined...
March 31, 2017: Stroke; a Journal of Cerebral Circulation
keyword
keyword
69170
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"