Zhang Hui, Xu Dingjie, Yuan Yuan, Wei Zhongqiu, Mao Na, Bei Mingjian, Gou Yu, Liu Guangyuan, Gao Xuemin, Li Shifeng, Geng Yucong, Yang Fang, Ross Summer, Xu Hong
Silicosis is the most common occupational lung disease in China, and is associated with a variety of complications, many of which are poorly understood. For example, recent data indicate that silicosis associates with the development of osteopenia, and in some cases this bone loss is severe, meeting criteria for osteoporosis. Although many factors are likely to contribute to this relationship, including a sedentary lifestyle in patients with advanced silicotic lung disease, we hypothesized that silica might directly reduce bone mineral density...
April 19, 2018: Toxicology and Applied Pharmacology