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https://www.readbyqxmd.com/read/29235004/surgical-resection-vs-ablative-therapies-through-a-laparoscopic-approach-for-hepatocellular-carcinoma-a-comparative-study
#1
Roberto Santambrogio, Matteo Barabino, Savino Bruno, Nicolò Mariani, Nirvana Maroni, Emanuela Bertolini, Giuseppe Franceschelli, Enrico Opocher
BACKGROUND: When compatible with the liver functional reserve, laparoscopic hepatic resection remains the treatment of choice for hepatocellular carcinoma while laparoscopic ablation therapies appear as a promising less invasive alternative. The aim of the study is to compare two homogeneous groups of patients submitted to either hepatic resection or thermoablation for the treatment of single hepatocellular carcinoma (≤ 3 cm). METHODS: We enrolled 264 cirrhotic patients out of 905 cases consecutively evaluated for hepatocellular carcinoma...
December 12, 2017: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
https://www.readbyqxmd.com/read/29234894/amputation-neuroma-mimicking-lymph-node-metastasis-of-remnant-gastric-cancer-a-case-report
#2
Kenichiro Furukawa, Yutaka Tanizawa, Kimihide Kusafuka, Noriyuki Nishiwaki, Keiichi Fujiya, Hayato Omori, Sanae Kaji, Makoto Hikage, Rie Makuuchi, Tomoyuki Irino, Masanori Tokunaga, Etsuro Bando, Taiichi Kawamura, Masanori Terashima
BACKGROUND: Amputation neuromas (ANs) are reactive hyperplasia of nerve tissues that occur after a trauma or surgery involving the peripheral nerves. Only two previous reports of ANs occurring around the stomach and post gastrectomy have been reported. We report the case of a patient with AN near the remnant stomach who underwent distal gastrectomy for gastric cancer. CASE PRESENTATION: A 76-year-old man underwent distal gastrectomy, D1+ lymphadenectomy, and Billroth-I reconstruction for early gastric cancer in another hospital at 63 years of age...
December 12, 2017: Surgical Case Reports
https://www.readbyqxmd.com/read/29234719/compression-stockings-as-an-effective-treatment-for-erythema-nodosum-case-series
#3
K B Golisch, S P Gottesman, R J Segal
Erythema nodosum (EN) is a septal panniculitis that is characterized clinically by tender, erythematous, subcutaneous nodules that are predominately localized on the pretibial lower legs. EN affects women more than men and can be idiopathic or secondary to another disease process such as infection or an immune response. Treatment options for erythema nodosum are suboptimal and often involve significant side effects or require a change in lifestyle. We investigated the effects of moderate 20 mmHg to 30 mmHg compression stockings as an alternative treatment method in two female patients with recurrent erythema nodosum...
December 2017: International Journal of Women's Dermatology
https://www.readbyqxmd.com/read/29234718/a-case-of-multiple-squamous-cell-carcinomas-arising-from-red-tattoo-pigment
#4
E Maxim, H Higgins, L D'Souza
Ornamental tattooing involves the administration of exogenous pigments into the skin to create a permanent design. Our case focuses on a 62-year-old woman who presented with an inflamed enlarging nodule on her right proximal calf, which arose within the red pigment of an ornamental tattoo. The nodule was diagnosed as squamous cell carcinoma (SCC) and subsequently excised. Over the course of the following year, the patient was diagnosed with a total of five additional SCCs that also arose within the red pigment of the tattoo...
December 2017: International Journal of Women's Dermatology
https://www.readbyqxmd.com/read/29234634/association-of-serum-ferritin-with-diabetes-and-alcohol-in-patients-with-non-viral-liver-disease-related-hepatocellular-carcinoma
#5
Rohan C Siriwardana, Madunil A Niriella, Anuradha Dassanayake, Dileepa Ediriweera, Bhagya Gunetilleke, Thenuka Sivasundaram, Janaka de Silva
INTRODUCTION: Non-alcoholic fatty liver disease is a leading cause for hepatocellular carcinoma (HCC) in Sri Lanka. Diabetes mellitus, alcohol abuse, and liver inflammation are known to increase the risk of HCC. The present study evaluates serum ferritin levels in a cohort of patients with non-viral HCC (nvHCC). METHODOLOGY: Consecutive patients with nvHCC presenting to the Colombo North Liver transplant Service, Ragama, from January 2012 to July 2013 were investigated...
November 2017: Liver Cancer
https://www.readbyqxmd.com/read/29234625/insight-into-differentiated-thyroid-cancer-gross-pathological-specimen-shrinkage-and-its-influence-on-tnm-staging
#6
Alexis Lacout, Emmanuel Chamorey, Juliette Thariat, Mostafa El Hajjam, Carole Chevenet, Renaud Schiappa, Pierre Yves Marcy
Introduction: This study aimed at comparing thyroid cancer staging when taking into account the differences between the "T" assessment" using ultrasound (US) and histopathological measurements. Material and Methods: This retrospective study included all consecutive differentiated follicular thyroid cancer (DTC) and medullary thyroid cancer (MTC) patients who underwent postoperative histopathological staging assessment at a single institution. Anaplastic thyroid carcinomas were excluded from the present study...
November 2017: European Thyroid Journal
https://www.readbyqxmd.com/read/29234267/incidental-detection-of-occult-thyroid-carcinoma-with-11c-choline-pet-ct-for-high-risk-prostate-cancer
#7
Adama Ouattara, Tiago Ribeiro de Oliveira, Serge Holz, Hannes Van den Bossche, David Strybol, Christophe Assenmacher, Wouter Everaerts, Gert De Meerleer, Steven Joniau
We report a case of a 65-year-old male patient with high-risk prostate cancer, re-staged with 11C-choline positron emission tomography/computed tomography (PET/CT) for prostate specific antigen recurrences 3 years after radical prostatectomy and adjuvant radiation therapy. In addition to 2 suspicious presacral lymph nodes which were resected and proven to be metastatic, PET/CT revealed a very high uptake in a calcified thyroid nodule. Evaluation with fine needle aspiration was suspicious for thyroid carcinoma and the patient underwent total thyroidectomy, confirming a non-metastatic encapsulated follicular variant of papillary thyroid carcinoma...
November 2017: Current Urology
https://www.readbyqxmd.com/read/29233839/genetics-of-tumors-of-the-adrenal-cortex
#8
Fidéline Bonnet-Serrano, Jerome Bertherat
This review describes the molecular alterations observed in the various types of tumors of the adrenal cortex, excluding Conn adenomas, especially the alterations identified by genomic approaches these last five years. Two main forms of bilateral adrenocortical tumors can be distinguished according to size and aspect of the nodules: primary pigmented nodular adrenal disease (PPNAD) which can be sporadic or part of Carney complex, and primary bilateral macro nodular adrenal hyperplasia (PBMAH). The bilateral nature of tumors suggests the existence of an underlying genetic predisposition...
December 12, 2017: Endocrine-related Cancer
https://www.readbyqxmd.com/read/29233112/napsin-a-levels-in-epithelial-lining-fluid-as-a-diagnostic-biomarker-of-primary-lung-adenocarcinoma
#9
Akifumi Uchida, Takuya Samukawa, Tomohiro Kumamoto, Masahiro Ohshige, Kazuhito Hatanaka, Yoshihiro Nakamura, Keiko Mizuno, Ikkou Higashimoto, Masami Sato, Hiromasa Inoue
BACKGROUND: It is crucial to develop novel diagnostic approaches for determining if peripheral lung nodules are malignant, as such nodules are frequently detected due to the increased use of chest computed tomography scans. To this end, we evaluated levels of napsin A in epithelial lining fluid (ELF), since napsin A has been reported to be an immunohistochemical biomarker for histological diagnosis of primary lung adenocarcinoma. METHODS: In consecutive patients with indeterminate peripheral lung nodules, ELF samples were obtained using a bronchoscopic microsampling (BMS) technique...
December 12, 2017: BMC Pulmonary Medicine
https://www.readbyqxmd.com/read/29232426/solitary-tender-nodule-on-the-back
#10
Claire O Dorfman, Christian W Oram, Nektarios Lountzis
No abstract text is available yet for this article.
November 2017: Cutis; Cutaneous Medicine for the Practitioner
https://www.readbyqxmd.com/read/29231951/phonomicrosurgery-in-vocal-fold-nodules-quantification-of-outcomes-in-professional-and-non-professional-voice-users
#11
Philipp P Caffier, Tatjana Salmen, Tatiana Ermakova, Eleanor Forbes, Seo-Rin Ko, Wen Song, Manfred Gross, Tadeus Nawka
There are few data demonstrating the specific extent to which surgical intervention for vocal fold nodules (VFN) improves vocal function in professional (PVU) and non-professional voice users (NVU). The objective of this study was to compare and quantify results after phonomicrosurgery for VFN in these patient groups. METHODS: In a prospective clinical study, surgery was performed via microlaryngoscopy in 37 female patients with chronic VFN manifestations (38±12 yrs, mean±SD). Pre- and postoperative evaluations of treatment efficacy comprised videolaryngostroboscopy, auditory-perceptual voice assessment, voice range profile (VRP), acoustic-aerodynamic analysis, and voice handicap index (VHI-9i)...
December 2017: Medical Problems of Performing Artists
https://www.readbyqxmd.com/read/29230956/prevalence-of-non-18-f-fluorodeoxyglucose-avid-incidental-findings-of-clinical-significance-on-whole-body-positron-emission-tomography-computed-tomography-a-review-of-500-consecutive-cases
#12
James A Sheldon, Kelvin K Yap, Kim L Taubman, Stephen M Schlicht
INTRODUCTION: The prevalence of incidental 18 F-fluorodeoxyglucose (FDG)-avid findings on positron emission tomography-computed tomography (PET/CT) has been extensively described. Few studies, however, have assessed the prevalence and significance of non-FDG-avid findings; pathology that is identified on review of the low-dose, non-contrast CT. The aim of this study was to determine the overall prevalence of non FDG-avid incidental findings on PET/CT and the prevalence of 'clinically significant' non FDG-avid pathology...
December 11, 2017: Journal of Medical Imaging and Radiation Oncology
https://www.readbyqxmd.com/read/29230559/increased-histopathological-yield-for-granulomatosis-with-polyangiitis-based-on-nasal-endoscopy-of-suspected-active-lesions
#13
Olga Beltrán Rodríguez-Cabo, Edgardo Reyes, Jorge Rojas-Serrano, Luis Felipe Flores-Suárez
PURPOSE: To present the results of an endoscopic and histopathologic evaluation of suspected nasal active granulomatosis with polyangiits (GPA) lesions, describe them as seen by the ENT specialist, and propose a guide for tissue sampling of the nasal cavity to improve the yield of confirmatory histology. METHODS: Randomly selected patients seen from December 1997-October 2007 had a thorough endoscopic nasal evaluation, preceded by careful cleansing of the nasal cavity...
December 11, 2017: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/29230286/asthma-mimic-case-report-and-literature-review-of-vocal-cord-nodule-associated-with-wheezing
#14
Muhammad Kashif, Tushi Singh, Ahsan Aslam, Misbahuddin Khaja
Asthma is a heterogeneous disease, usually characterized by chronic airway inflammation. Various clinical conditions can mimic asthma, such as foreign body aspiration, subglottic stenosis, congestive heart failure, diffuse panbronchiolitis, aortic arch anomalies, reactive airway dysfunction syndrome, chronic obstructive pulmonary disease, retrosternal goiter, vocal cord tumors, other airway tumors, and vocal cord dysfunction. Upper airway obstruction can be a life-threatening emergency. Here, we present the case of a 58-year-old female with recurrent hospital visits for wheezing and exacerbations of asthma, who was later found to have a vocal cord nodule confirmed to be squamous cell carcinoma, which was mimicking like asthma...
2017: SAGE Open Medical Case Reports
https://www.readbyqxmd.com/read/29230266/-shoulder-tumor-of-startling-appearance
#15
Ilhame Naciri, Baderddine Hassam
Chondrosarcoma is a malignant tumor of bone of mesenchymal origin which usually occurs in people after age 40 at the level of the pelvis and the shoulder. We report the case of a 65-year old female patient, with no particular past medical history, with impaired general condition, hospitalized for exploration of a large tumor of the right shoulder, evolving over 3 years. Clinical examination showed giant, humpbacked, hard, adherent tumor measuring 44 × 32 cm along its longer axis, with inflammatory signs associated with signs of vasculo-nervous compression...
2017: Pan African Medical Journal
https://www.readbyqxmd.com/read/29230133/invasive-insular-thyroid-carcinoma-presenting-as-nonparalytic-dysphonia
#16
Blake S Raggio, Blair M Barton, Maria C Grant, Judith A Fornadley, Jeffrey P Marino
Background: Patients with suspected thyroid malignancy often undergo preoperative laryngeal examination with a focus on vocal fold mobility. We present the unique case of a patient with invasive thyroid carcinoma who presented with dysphonia despite intact vocal fold motion. Case Report: A 73-year-old female with a remote thyroid lobectomy presented with dysphonia. Thyroid ultrasound and fine-needle aspiration revealed a 1.1-cm nodule consistent with a colloid cyst...
2017: Ochsner Journal
https://www.readbyqxmd.com/read/29230132/primary-undifferentiated-pleomorphic-sarcoma-of-the-penis
#17
Hyung Sun Yoo, Suma Satti, Marc Matrana
Background: Primary penile sarcoma is a rare disease that affects men of all ages. Different subtypes of primary penile sarcoma exist, with the rarest being pleomorphic sarcoma. Delays in presentation and diagnosis of primary penile sarcoma have been reported because of its benign-appearing presenting features and rarity. If penile sarcoma is left untreated, the clinical consequence is metastasis that is fatal in most cases. Case Report: We report an extremely rare case of undifferentiated pleomorphic sarcoma of the penis in a 59-year-old patient who initially presented with a slow-growing penile nodule...
2017: Ochsner Journal
https://www.readbyqxmd.com/read/29229574/merkel-cell-carcinoma-an-update-and-review-part-1-pathogenesis-diagnosis-and-staging
#18
REVIEW
Kathleen Coggshall, Tiffany L Tello, Jeffrey P North, Siegrid S Yu
Merkel cell carcinoma (MCC) is an uncommon primary cutaneous neuroendocrine cancer. It most commonly presents as an indurated plaque or nodule on sun-damaged skin in elderly patients and is characterized by high rates of local recurrence and nodal metastasis. Survival at five years is 51% for local disease and as low as 14% for distant disease, which underscores the aggressive nature of this tumor and challenges in management. Advances in immunology and molecular genetics have broadened our understanding of the pathophysiology of MCC and expanded our therapeutic arsenal...
December 8, 2017: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/29229107/clinical-characterization-of-52-patients-with-immunoglobulin-g4-related-disease-in-a-single-tertiary-center-in-japan-special-reference-to-lung-disease-in-thoracic-high-resolution-computed-tomography
#19
Takeshi Saraya, Kosuke Ohkuma, Masachika Fujiwara, Chika Miyaoka, Shoko Wada, Takayasu Watanabe, Sunao Mikura, Manami Inoue, Miku Oda, Mitsuru Sada, Yukari Ogawa, Kojiro Honda, Masaki Tamura, Takuma Yokoyama, Daisuke Kurai, Haruyuki Ishii, Hajime Takizawa
BACKGROUND: Immunoglobulin G4-related disease (IgG4-RD) is a rare multi-organ disorder. Physicians rarely encounter patients with IgG4-RD and its range of symptoms. METHODS: To elucidate the clinical characterization of IgG4-RD, along with the clinical significance of lung involvement, we retrospectively reviewed the medical records of patients who satisfied the comprehensive diagnostic criteria for IgG4-RD. RESULTS: We identified 52 patients with IgG4-RD...
November 2017: Respiratory Medicine
https://www.readbyqxmd.com/read/29228652/clinical-characteristics-and-programmed-cell-death-ligand-1-expression-in-adenocarcinoma-in-situ-and-minimally-invasive-adenocarcinoma-of-lung
#20
Renke Yu, Zhengfu He, Ying Lou, Hanliang Jiang, Yuhui Wu, Zhen Liu, Hongming Pan, Weidong Han
Objectives: According to the IASLC/ATS/ERS 2011 classification, there are two new conceptions of lung adenocarcinoma, adenocarcinoma in situ (AIS), minimally invasive adenocarcinoma (MIA), which are very early stages of lung adenocarcinoma. This study aimed to analyze clinical features of AIS and MIA and determine the expression profile of PD-L1 in AIS and MIA. Results: In all 274 patients, 77 were diagnosed as AIS and 197 as MIA. We accidentally found 4 patients with recurrence, which were all MIA...
November 17, 2017: Oncotarget
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