Behrouz Zand, Rebecca A Previs, Niki M Zacharias, Rajesha Rupaimoole, Takashi Mitamura, Archana Sidalaghatta Nagaraja, Michele Guindani, Heather J Dalton, Lifeng Yang, Joelle Baddour, Abhinav Achreja, Wei Hu, Chad V Pecot, Cristina Ivan, Sherry Y Wu, Christopher R McCullough, Kshipra M Gharpure, Einav Shoshan, Sunila Pradeep, Lingegowda S Mangala, Cristian Rodriguez-Aguayo, Ying Wang, Alpa M Nick, Michael A Davies, Guillermo Armaiz-Pena, Jinsong Liu, Susan K Lutgendorf, Keith A Baggerly, Menashe Bar Eli, Gabriel Lopez-Berestein, Deepak Nagrath, Pratip K Bhattacharya, Anil K Sood
BACKGROUND: The clinical and biological effects of metabolic alterations in cancer are not fully understood. METHODS: In high-grade serous ovarian cancer (HGSOC) samples (n = 101), over 170 metabolites were profiled and compared with normal ovarian tissues (n = 15). To determine NAT8L gene expression across different cancer types, we analyzed the RNA expression of cancer types using RNASeqV2 data available from the open access The Cancer Genome Atlas (TCGA) website (https://www...
January 26, 2016: Journal of the National Cancer Institute