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https://www.readbyqxmd.com/read/28211341/food-protein-induced-enterocolitis-syndrome
#1
REVIEW
A Nowak-Węgrzyn, E Jarocka-Cyrta, Apb Moschione Castro
Food protein-induced enterocolitis syndrome (FPIES) is a non-IgE-, cell-mediated food allergy of unknown prevalence and pathophysiology. Onset is typically during the first year of life; seafood-induced FPIES may start in adulthood. Acute FPIES manifests within 1-4 hours after ingestion with repetitive emesis, pallor, and lethargy progressing to dehydration and hypovolemic shock in 15% of cases. Chronic FPIES manifests with intermittent emesis, watery diarrhea, and poor growth progressing to dehydration and hypovolemic shock over a period of days to weeks...
2017: Journal of Investigational Allergology & Clinical Immunology
https://www.readbyqxmd.com/read/28192147/systemic-innate-immune-activation-in-food-protein-induced-enterocolitis-syndrome-fpies
#2
Ritobrata Goswami, Ana Belen Blazquez, Roman Kosoy, Adeeb Rahman, Anna Nowak-Wegrzyn, M Cecilia Berin
BACKGROUND: Food protein induced enterocolitis syndrome (FPIES) is a non-IgE-mediated food allergy of infancy whose pathophysiology is poorly understood. OBJECTIVES: We set out to identify and phenotype allergen-responsive cells in peripheral blood of a cohort of subjects undergoing supervised food challenge for FPIES. METHODS: We profiled antigen-responsive cells in peripheral blood mononuclear cells by flow cytometry, and examined cells in whole blood obtained before and after challenge by CyTOF mass cytometry and RNAseq...
February 9, 2017: Journal of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/28157992/generalized-high-spectral-resolution-lidar-technique-with-a-multimode-laser-for-aerosol-remote-sensing
#3
Zhongtao Cheng, Dong Liu, Yupeng Zhang, Chong Liu, Jian Bai, Dan Wang, Nanchao Wang, Yudi Zhou, Jing Luo, Yongying Yang, Yibing Shen, Lin Su, Liming Yang
High-spectral-resolution lidar (HSRL) is a powerful tool for atmospheric aerosol remote sensing. The current HSRL technique often requires a single longitudinal mode laser as the transmitter to accomplish the spectral discrimination of the aerosol and molecular scattering conveniently. However, single-mode laser is cumbersome and has very strict requirements for ambient stability, making the HSRL instrument not so robust in many cases. In this paper, a new HSRL concept, called generalized HSRL technique with a multimode laser (MML-gHSRL), is proposed, which can work using a multimode laser...
January 23, 2017: Optics Express
https://www.readbyqxmd.com/read/28157119/reduce-beam-hardening-artifacts-of%C3%A2-polychromatic-x-ray-computed-tomography-by-an-iterative-approximation-approach
#4
Hongli Shi, Zhi Yang, Shuqian Luo
BACKGROUND: The beam hardening artifact is one of most important modalities of metal artifact for polychromatic X-ray computed tomography (CT), which can impair the image quality seriously. OBJECTIVE: An iterative approach is proposed to reduce beam hardening artifact caused by metallic components in polychromatic X-ray CT. METHODS: According to Lambert-Beer law, the (detected) projections can be expressed as monotonic nonlinear functions of element geometry projections, which are the theoretical projections produced only by the pixel intensities (image grayscale) of certain element (component)...
February 3, 2017: Journal of X-ray Science and Technology
https://www.readbyqxmd.com/read/28152648/changes-in-apparent-fibre-density-and-track-weighted-imaging-metrics-in-white-matter-following-experimental-traumatic-brain-injury
#5
David Wright, Leigh Johnston, Jeff Kershaw, Roger Ordidge, Terence John O'Brien, Sandy Richard Shultz
Traumatic brain injury (TBI) has been assessed with diffusion tensor imaging (DTI), a commonly used magnetic resonance imaging (MRI) marker for white matter integrity. However, as the DTI model only fits a single fibre orientation, results can become confounded in regions of 'crossing' white matter fibres. In contrast, constrained spherical deconvolution estimates a fibre orientation distribution directly from high angular resolution diffusion weighted images. Consequently, constrained spherical deconvolution-based measures such as apparent fibre density and track-weighted imaging metrics (including tract density imaging, average pathlength mapping, and mean curvature), may be more sensitive than DTI metrics to white matter injury following TBI...
February 3, 2017: Journal of Neurotrauma
https://www.readbyqxmd.com/read/28149661/biomechanical-podiatric-evaluation-in-an-italian-cohort-of-patients-with-systemic-sclerosis-a-pilot-study
#6
Susanna Maddali Bongi, Giovanni Ravenni, Benedetta Ciampi, Angela Del Rosso, Khadija El Aoufy
OBJECTIVE: Foot problems are often present in Systemic Sclerosis (SSc) patients, however studies regarding podiatric problems related to SSc are lacking and there are no data evaluating the foot biomechanical changes. The aim of the present pilot study was to evaluate podiatric problems in an Italian cohort of SSc patients by assessing received podiatric services, foot pain and disability and biomechanical foot deformity. MATERIAL AND METHODS: 25 consecutive SSc patients were enrolled from the Division of Rheumatology, University of Florence...
December 2016: European Journal of Rheumatology
https://www.readbyqxmd.com/read/28134855/low-coherence-interferometric-fiber-optic-sensors-with-potential-applications-as-biosensors
#7
Marzena Hirsch, Daria Majchrowicz, Paweł Wierzba, Matthieu Weber, Mikhael Bechelany, Małgorzata Jędrzejewska-Szczerska
Fiber-optic Fabry-Pérot interferometers (FPI) can be applied as optical sensors, and excellent measurement sensitivity can be obtained by fine-tuning the interferometer design. In this work, we evaluate the ability of selected dielectric thin films to optimize the reflectivity of the Fabry-Pérot cavity. The spectral reflectance and transmittance of dielectric films made of titanium dioxide (TiO₂) and aluminum oxide (Al₂O₃) with thicknesses from 30 to 220 nm have been evaluated numerically and compared...
January 28, 2017: Sensors
https://www.readbyqxmd.com/read/28131968/effect-of-intravenous-plasma-transfusion-on-granulocyte-and-monocyte-oxidative-and-phagocytic-activity-in-dairy-calves-with-failure-of-passive-immunity
#8
Victoria C Yang, Maire C Rayburn, Munashe Chigerwe
Plasma administration has been recommended in calves older than 48h with failure of passive immunity (FPI) to provide immunity consistent with adequate colostral ingestion. However, the protective serum immunoglobulin G (IgG) concentrations (≥1000mg/dL) of plasma derived IgG only lasts up to 12h. In addition to IgG, maternally derived colostral cells also confer immunity. The objective of the study was to determine the effect of intravenous plasma transfusion on granulocyte and monocyte oxidative and phagocytic activity in calves with FPI...
January 21, 2017: Research in Veterinary Science
https://www.readbyqxmd.com/read/28120606/a-very-unusual-case-of-food-allergy-between-fpies-and-ige-mediated-food-allergy
#9
S Miceli Sopo, S Monaco, G Cerchiara, G Bersani
Food protein induced enterocolitis syndrome (FPIES) is a food-related gastrointestinal hypersensitivity disorder, probably non-IgE-mediated. Over the years, various diagnostic criteria have been proposed to identify FPIES. In the last few years, there was an increased interest from researchers about FPIES's syndrome, that frequently brought to discover new aspects of this disease. We describe an unusual case of FPIES to egg in a 21-months-old child, because of its clinical characteristics that reflect some aspects of IgE-mediated allergy and other of non IgE-mediated allergy...
January 2017: European Annals of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/28117255/examination-of-the-correlation-between-foot-morphology-measurements-using-pedography-and-radiographic-measurements
#10
Kentaro Inui, Kazuya Ikoma, Kan Imai, Suzuyo Ohashi, Masahiro Maki, Masamitsu Kido, Yusuke Hara, Yoshinobu Oka, Hiroyoshi Fujiwara, Toshikazu Kubo
Pedography provides excellent visualization of the footprint. However, the correlation between the footprint images and radiographic measures has not been thoroughly evaluated. Therefore, the objectives of our study were to examine the correlation between the pedography-based measures of foot morphology and radiographic measurements and to propose reference values for the diagnosis of flatfoot using footprint imaging. The plantar footprints of 100 right feet were photographed using a pedography standing platform...
January 20, 2017: Journal of Foot and Ankle Surgery: Official Publication of the American College of Foot and Ankle Surgeons
https://www.readbyqxmd.com/read/28108621/are-physical-measures-related-to-patient-centred-outcomes-in-ards-survivors
#11
Kitty S Chan, Lisa Aronson Friedman, Victor D Dinglas, Catherine L Hough, Carl Shanholtz, E Wesley Ely, Peter E Morris, Pedro A Mendez-Tellez, James C Jackson, Ramona O Hopkins, Dale M Needham
OBJECTIVE: To inform selection of physical measures for studies of acute respiratory distress syndrome (ARDS) survivors within 12 months of ARDS. METHODS: Secondary analysis of data from 6-month survivors participating in a US multicentre prospective study (ARDSNet Long-Term Outcome Study, N=134) or a multisite prospective study in Baltimore, Maryland, USA (Improving Care of Acute Lung Injury Patients, N=99). Physical measures, assessed at 6-month follow-up, were categorised according to the WHO's International Classification of Disability and Health: body functions and structures, activity and participation...
January 20, 2017: Thorax
https://www.readbyqxmd.com/read/28099164/investigation-of-time-resolved-proton-radiography-using-x-ray-flat-panel-imaging-system
#12
K-W Jee, R Zhang, E H Bentefour, P J Doolan, E Cascio, G Sharp, J Flanz, H-M Lu
Proton beam therapy benefits from the Bragg peak and delivers highly conformal dose distributions. However, the location of the end-of-range is subject to uncertainties related to the accuracy of the relative proton stopping power estimates and thereby the water-equivalent path length (WEPL) along the beam. To remedy the range uncertainty, an in vivo measurement of the WEPL through the patient, i.e. a proton-range radiograph, is highly desirable. Towards that goal, we have explored a novel method of proton radiography based on the time-resolved dose measured by a flat panel imager (FPI)...
March 7, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/28057433/cytokine-profile-after-oral-food-challenge-in-infants-with-food-protein-induced-enterocolitis-syndrome
#13
Mitsuaki Kimura, Yasunori Ito, Masaki Shimomura, Hideaki Morishita, Takaaki Meguro, Yuichi Adachi, Shiro Seto
BACKGROUND: Although food protein-induced enterocolitis syndrome (FPIES) is supposed to be caused by inflammation, the role of cytokines has not yet been clarified. METHODS: To elucidate the role of cytokines in the development of symptoms and abnormal laboratory findings at an oral food challenge (OFC), changes in serum cytokine levels were analyzed for 6 OFCs in 4 patients with FPIES. The result of OFC was judged positive if any gastrointestinal (GI) symptoms (vomiting, diarrhea, or bloody stool) were induced...
January 2, 2017: Allergology International: Official Journal of the Japanese Society of Allergology
https://www.readbyqxmd.com/read/28052802/characteristics-of-children-with-food-protein-induced-enterocolitis-and-allergic-proctocolitis
#14
Ebru Arik Yilmaz, Ozge Soyer, Ozlem Cavkaytar, Betul Karaatmaca, Betul Buyuktiryaki, Umit M Sahiner, Bulent E Sekerel, Cansin Sackesen
BACKGROUND: The aim of this study was to determine and compare the clinical and laboratory features of food protein-induced enterocolitis syndrome (FPIES) and food protein-induced allergic proctocolitis (FPIAP), and to provide information about the short-term prognoses. METHOD: Children diagnosed with FPIES or FPIAP between 2010 and 2015 were enrolled in this study. RESULTS: Overall, 64 infants (37 FPIAP, 27 FPIES) were evaluated, with the average age at the onset of symptoms being significantly lower in the patients with FPIAP than in the patients with FPIES (2 months [1-3 months] versus 4 months [1...
January 1, 2017: Allergy and Asthma Proceedings:
https://www.readbyqxmd.com/read/28044312/optimization-of-contrast-enhanced-breast-imaging-analysis-using-a-cascaded-linear-system-model
#15
Yue-Houng Hu, David A Scaduto, Wei Zhao
PURPOSE: Contrast-enhanced (CE) breast imaging involves the injection contrast agents (i.e., iodine) to increase conspicuity of malignant lesions. CE imaging may be used in conjunction with digital mammography (DM) or digital breast tomosynthesis (DBT) and has shown promise in improving diagnostic specificity. Both CE-DM and CE-DBT techniques require optimization as clinical diagnostic tools. Physical factors including x-ray spectra, subtraction technique, and the signal from iodine contrast, must be considered to provide the greatest object detectability and image quality...
January 2017: Medical Physics
https://www.readbyqxmd.com/read/28042008/does-time-heal-all-wounds-experimental-diffuse-traumatic-brain-injury-results-in-persisting-histopathology-in-the-thalamus
#16
Theresa Currier Thomas, Sarah B Ogle, Benjamin M Rumney, Hazel G May, P David Adelson, Jonathan Lifshitz
BACKGROUND: Thalamic dysfunction has been implicated in overall chronic neurological dysfunction after traumatic brain injury (TBI), however little is known about the underlying histopathology. In experimental diffuse TBI (dTBI), we hypothesize that persisting histopathological changes in the ventral posteromedial (VPM) nucleus of the thalamus is indicative of progressive circuit reorganization. Since circuit reorganization in the VPM impacts the whisker sensory system, the histopathology could explain the development of hypersensitivity to whisker stimulation by 28days post-injury; similar to light and sound hypersensitivity in human TBI survivors...
December 29, 2016: Behavioural Brain Research
https://www.readbyqxmd.com/read/28017714/long-term-valve-performance-of-tavr-and-savr-a-report-from-the-partner-i-trial
#17
Melissa A Daubert, Neil J Weissman, Rebecca T Hahn, Philippe Pibarot, Rupa Parvataneni, Michael J Mack, Lars G Svensson, Deepika Gopal, Samir Kapadia, Robert J Siegel, Susheel K Kodali, Wilson Y Szeto, Raj Makkar, Martin B Leon, Pamela S Douglas
OBJECTIVES: The aim of this study was to evaluate the long-term performance of transcatheter aortic valve replacement (TAVR) and surgical aortic valve replacement (SAVR) through longitudinal echocardiographic analysis. BACKGROUND: The long-term performance of the SAPIEN TAVR is not well-described. Therefore, we examined the hemodynamic and valvular profile of the SAPIEN TAVR over 5 years. METHODS: All patients receiving TAVR or SAVR with first post-implant (FPI) and 5-year echoes were analyzed for aortic valve (AV) peak velocity, AV mean gradient, AV area, peak left ventricular (LV) outflow tract and in-stent velocities, Doppler velocity index, aortic regurgitation (AR), LV mass index, stroke volume index, and cardiac index...
December 8, 2016: JACC. Cardiovascular Imaging
https://www.readbyqxmd.com/read/28005971/the-anatomy-of-american-football-evidence-from-7-years-of-nfl-game-data
#18
Konstantinos Pelechrinis, Evangelos Papalexakis
How much does a fumble affect the probability of winning an American football game? How balanced should your offense be in order to increase the probability of winning by 10%? These are questions for which the coaching staff of National Football League teams have a clear qualitative answer. Turnovers are costly; turn the ball over several times and you will certainly lose. Nevertheless, what does "several" mean? How "certain" is certainly? In this study, we collected play-by-play data from the past 7 NFL seasons, i...
2016: PloS One
https://www.readbyqxmd.com/read/28005853/optical-fiber-vector-flow-sensor-based-on-a-silicon-fabry-perot-interferometer-array
#19
Guigen Liu, Qiwen Sheng, Weilin Hou, Ming Han
We report a miniature fiber-optic water vector flow sensor based on an array of silicon Fabry-Perot interferometers (FPIs). The flow sensor is composed of four silicon FPIs, one in the center with the other three equally distributed around it. The center FPI is heated by a cw laser at 980 nm, which is guided through the lead-in single mode fiber. The temperature structure established within the sensor head due to laser heating is a function of the flow vector (speed and direction), which can be deduced from the wavelength shifts of the four FPIs...
October 15, 2016: Optics Letters
https://www.readbyqxmd.com/read/27984205/definition-of-insulin-resistance-affects-prevalence-rate-in-pediatric-patients-a-systematic-review-and-call-for-consensus
#20
Marloes P van der Aa, Catherijne A J Knibbe, Anthonius de Boer, Marja M J van der Vorst
BACKGROUND: As a result of the rising prevalence of childhood obesity, there is an increasing interest in the type 2 diabetes mellitus precursor insulin resistance (IR). The aim of this study is to review definitions (methods and cutoff values) to define IR in children and to apply these definitions to a previously described obese pediatric population. METHODS: A systematic literature review on prevalence and/or incidence rates in children was performed. The extracted definitions were applied to an obese pediatric population...
February 1, 2017: Journal of Pediatric Endocrinology & Metabolism: JPEM
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