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https://www.readbyqxmd.com/read/28526630/what-is-the-impact-of-bariatric-surgery-on-erectile-function-a%C3%A2-systematic-review-and-meta-analysis
#1
REVIEW
Felipe Placco Araujo Glina, Júlia Walter de Freitas Barboza, Victor Moises Nunes, Sidney Glina, Wanderley Marques Bernardo
INTRODUCTION: Obesity is a worldwide public health issue that has severe psychological and social implications. Erectile dysfunction also is a prevalent clinical situation, and obesity is one of the primary risk factors for its development. AIM: To determine whether bariatric surgery can lessen erectile dysfunction in obese men because of evidence showing that weight loss in obese men contributes to decreasing erectile dysfunction and bariatric surgery contributes to significant weight loss...
May 16, 2017: Sexual Medicine Reviews
https://www.readbyqxmd.com/read/28449717/a-review-of-patient-reported-outcome-measures-to-assess-female-infertility-related-quality-of-life
#2
REVIEW
Helen Kitchen, Natalie Aldhouse, Andrew Trigg, Roberto Palencia, Stephen Mitchell
BACKGROUND: Infertility has a negative impact on quality of life (QoL) and well-being of affected individuals and couples. A variety of patient-reported outcome (PRO) measures to assess infertility-related QoL are available; however, there is a concern regarding potential issues with their development methodology, validation and use. This review aimed to i) identify PRO measures used in infertility interventional studies ii) assess validation evidence to identify a reliable, valid PRO measure to assess changes in QoL or treatment satisfaction in clinical studies with female patients following treatment with novel therapies iii) identify potential gaps in evidence for validity...
April 27, 2017: Health and Quality of Life Outcomes
https://www.readbyqxmd.com/read/28447178/an-mri-guided-telesurgery-system-using-a-fabry-perot-interferometry-force-sensor-and-a-pneumatic-haptic-device
#3
Hao Su, Weijian Shang, Gang Li, Niravkumar Patel, Gregory S Fischer
This paper presents a surgical master-slave teleoperation system for percutaneous interventional procedures under continuous magnetic resonance imaging (MRI) guidance. The slave robot consists of a piezoelectrically actuated 6-degree-of-freedom (DOF) robot for needle placement with an integrated fiber optic force sensor (1-DOF axial force measurement) using the Fabry-Perot interferometry (FPI) sensing principle; it is configured to operate inside the bore of the MRI scanner during imaging. By leveraging the advantages of pneumatic and piezoelectric actuation in force and position control respectively, we have designed a pneumatically actuated master robot (haptic device) with strain gauge based force sensing that is configured to operate the slave from within the scanner room during imaging...
April 26, 2017: Annals of Biomedical Engineering
https://www.readbyqxmd.com/read/28447044/molecular-and-phylogenetic-characterization-of-thelohanellus-boggoti-qadri-1962-cnidaria-myxosporea-bivalvulida-infecting-the-fin-of-indian-minor-carp-labeo-dero-hamilton-1822
#4
Harpreet Kaur, Aditya Gupta
A myxozoan parasite belonging to the genus Thelohanellus Kudo, 1933 (Cnidaria, Myxosporea, Bivalvulida) was isolated from the fins of Labeo dero inhabiting Ranjit Sagar Wetland, Punjab, India. The plasmodium was 0.5-0.7 mm in diameter each containing 80- 100 number of myxospores. Myxospores were egg shaped to ovoidal in valvular view having bluntly pointed anterior and broad rounded posterior end measuring 8.36x 4.77 µm. Polar capsule was single, broadly pyriform in shape, measuring 4.77x3.98 µm in size containing a polar filament coiled perpendicular to the longitudinal axis of myxospore body making 7-9 turns...
March 2017: Molecular Biology Research Communications
https://www.readbyqxmd.com/read/28437906/temperature-insensitive-fiber-optic-fabry-perot-interferometer-based-on-special-air-cavity-for-transverse-load-and-strain-measurements
#5
Yongfeng Wu, Yundong Zhang, Jing Wu, Ping Yuan
We experimentally demonstrate transverse load and strain sensing based on a fiber optic Fabry-Perot interferometer (FPI) with special air cavity, which was created by fusion splicing single mode fiber (SMF), hollow core fiber (HCF) and several electrical arc discharges. The cavity height of this structure is higher than the cladding diameter of SMF so that it can sense transverse load with high sensitivity. The transverse load sensitivity of this air cavity FPI sensor is 1.31 nm∕N and about 5 times more sensitive compared to the current fiber tip interferometer (0...
April 17, 2017: Optics Express
https://www.readbyqxmd.com/read/28433746/transforming-growth-factor-beta-1-signaling-regulates-neuroinflammation-and-apoptosis-in-mild-traumatic-brain-injury
#6
Rachel K Patel, Nithisha Prasad, Ram Kuwar, Debanjan Haldar, P M Abdul-Muneer
Mild Traumatic brain injury (mTBI) is a low-level injury, which often remains undiagnosed, and in most cases it leads to death and disability as it advances as secondary injury. Therefore, it is important to study the underlying signaling mechanisms of mTBI-associated neurological ailments. While transforming growth factor-beta1 (TGF-β1) has a significant role in inflammation and apoptosis in myriads of other pathophysiological conditions, the precise function of increased TGF-β1 after mTBI is unknown. In this study, our objective is to study the physiological relevance and associated mechanisms of TGF-β1-mediated inflammation and apoptosis in mTBI...
April 19, 2017: Brain, Behavior, and Immunity
https://www.readbyqxmd.com/read/28432705/prognosis-of-infantile-food-protein-induced-enterocolitis-syndrome-in-japan
#7
Mitsuaki Kimura, Masaki Shimomura, Hideaki Morishita, Takaaki Meguro
BACKGROUND: Although the serum C-reactive protein (CRP) level and the percentage of eosinophils in peripheral blood (Eo) are increased at onset in infants with food protein-induced enterocolitis syndrome (FPIES), the relationship of these laboratory findings with the prognosis is presently unknown. METHODS: Correlations of the serum CRP levels and Eo at onset with the prognosis was analyzed in 32 patients with FPIES caused by cow's milk (CM). RESULTS: The rate of tolerance acquisition was 18...
April 22, 2017: Pediatrics International: Official Journal of the Japan Pediatric Society
https://www.readbyqxmd.com/read/28427879/food-protein-induced-enterocolitis-syndrome-in-australia-a%C3%A2-population-based-study-2012-2014
#8
Sam Mehr, Katie Frith, Elizabeth H Barnes, Dianne E Campbell
BACKGROUND: Food protein-induced enterocolitis syndrome (FPIES) is a non-IgE-mediated gastrointestinal allergic disorder. Large population-based FPIES studies are lacking. OBJECTIVE: We sought to determine the incidence and clinical characteristics of FPIES in Australian infants. METHODS: An Australia-wide survey (2012-2014) was undertaken through the Australian Paediatric Surveillance Unit, with monthly notification of new cases of acute FPIES in infants aged less than 24 months by 1400 participating pediatricians...
April 18, 2017: Journal of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/28411905/fpies-the-dark-side-of-food-allergy
#9
EDITORIAL
C A Sánchez-Salguero
No abstract text is available yet for this article.
May 2017: Allergologia et Immunopathologia
https://www.readbyqxmd.com/read/28394688/distance-between-the-malleoli-and-the-grounda-new-clinical-method-to-measure-leg-length-discrepancy
#10
Estela Gomez Aguilar, Águeda Gómez Domínguez, Carolina Peña-Algaba, José M Castillo-López
BACKGROUND: The aim of this work is to introduce a useful method for the clinical diagnosis of leg-length inequality: distance between the malleoli and the ground (DMG). METHODS: A transversal observational study was performed on 17 patients with leg-length discrepancy. Leg-length inequality was determined with different clinical methods: with a tape measure in a supine position from the anterior superior iliac spine (ASIS) to the internal and external malleoli, as the difference between the iliac crests when standing (pelvimeter), and as asymmetry between ASISs (PALpation Meter [PALM]; A&D Medical Products Healthcare, San Jose, California)...
March 2017: Journal of the American Podiatric Medical Association
https://www.readbyqxmd.com/read/28394675/influence-of-age-sex-and-anthropometric-determinants-on-the-foot-posture-index-in-a-pediatric-population
#11
Ana María Jimenez-Cebrian, María Francisca Morente-Bernal, Pedro Daniel Román-Bravo, Juan Francisco Saucedo-Badía, Juan Antonio Alonso-Ríos, Alonso Montiel-Luque
BACKGROUND: The Foot Posture Index (FPI) is a clinical tool for diagnosis that aims to quantify the grade of a foot position as neutral, pronated, or supinated. Its purpose is to develop a simple six-factor method for rating foot posture with an easy and quantitative result. We evaluated possible differences in the FPI by sex and the influences of age, weight, height, foot size, and body mass index (BMI) on foot posture. METHODS: In 150 asymptomatic children (79 boys and 71 girls) aged 8 to 13 years, we determined weight, height, BMI, and FPI in the bipedal, static, and relaxed position...
March 2017: Journal of the American Podiatric Medical Association
https://www.readbyqxmd.com/read/28390583/a-systematic-review-of-food-protein-induced-enterocolitis-syndrome-from-the-last-40-years
#12
REVIEW
Sara Manti, Salvatore Leonardi, Annamaria Salpietro, Giuliana Del Campo, Carmelo Salpietro, Caterina Cuppari
OBJECTIVE: To provide a complete, exhaustive summary of current literature relevant to food protein-induced enterocolitis syndrome (FPIES). DATA SOURCES: Data have been extracted from PubMed and Science Direct databases. STUDY SELECTIONS: Following the Preferred Reporting Items for Systematic Reviews and Meta-analysis guidelines, a literature search for peer-reviewed journal articles in English through January 1975 with updates through October 2016 was conducted...
April 2017: Annals of Allergy, Asthma & Immunology
https://www.readbyqxmd.com/read/28375580/inflammatory-events-during-food-protein-induced-enterocolitis-syndrome-reactions
#13
Valentina Pecora, Giusi Prencipe, Rocco Valluzzi, Lamia Dahdah, Antonella Insalaco, Antonella Cianferoni, Fabrizio De Benedetti, Alessandro Fiocchi
BACKGROUND: An increasing number of infants are diagnosed with food protein induced enterocolitis syndrome (FPIES), a non-IgE-mediated food allergy. Until now, T-cell, food-specific mechanisms have been hypothesized. METHODS: 16 children (11M, 5F), affected by FPIES from cow's milk, wheat, fruit, rice and others, experienced 25 acute episodes managed at our Emergency Department (ED) and eight FPIES reactions during oral food challenges (OFC). We compared the laboratory data in resting conditions, in absence of infectious diseases, with data collected during the 25 acute ED episodes (blood samples drawn at 2 to 12 hours) and the eight positive OFCs (three samples at 2, 6 and 12 hours)...
April 4, 2017: Pediatric Allergy and Immunology
https://www.readbyqxmd.com/read/28362782/self-gauged-fiber-optic-micro-heater-with-an-operation-temperature-above-1000%C3%A2-c
#14
Guigen Liu, Qiwen Sheng, Dustin Dam, Jiong Hua, Weilin Hou, Ming Han
We report a fiber-optic micro-heater based on a miniature crystalline silicon Fabry-Perot interferometer (FPI) fusion spliced to the endface of a single-mode fiber. The silicon FPI, having a diameter of 100 μm and a length of 10 or 200 μm, is heated by a 980 nm laser diode guided through the lead-in fiber, leading to a localized hot spot with a temperature that can be conveniently tuned from the ambient temperature to >1000°C in air. In the meantime, using a white light system operating in the 1550 nm wavelength window where the silicon is transparent, the silicon FPI itself also serves as a thermometer with high resolution and high speed for convenient monitoring and precise control of the heater temperature...
April 1, 2017: Optics Letters
https://www.readbyqxmd.com/read/28357328/francisella-iglg-protein-and-the-duf4280-proteins-paar-like-proteins-in-non-canonical-type-vi-secretion-systems
#15
COMMENT
Claire Lays, Eric Tannier, Thomas Henry
Type VI secretion systems (T6SS) are bacterial molecular machines translocating effector proteins into target cells. T6SS are widely present in Gram-negative bacteria where they predominantly act to kill neighboring bacteria. This secretion system is reminiscent of the tail of contractile bacteriophages and consists of a contractile sheath anchored in the bacterial envelope and an inner tube made of stacks of the Hcp protein. The Hcp tube is capped with a VgrG trimer and a spike protein termed PAAR, which acts as the membrane-puncturing device...
October 29, 2016: Microbial Cell
https://www.readbyqxmd.com/read/28355201/sex-and-age-differences-in-phenylephrine-mechanisms-and-outcomes-after-piglet-brain-injury
#16
Victor Curvello, Hugh Hekierski, John Riley, Monica Vavilala, William M Armstead
BACKGROUND: Traumatic brain injury (TBI) is the leading cause of injury related death in children, with boys and children under 4 having particularly poor outcomes. Cerebral autoregulation is often impaired after TBI, contributing to poor outcome. In prior studies of newborn pigs, phenylephrine (Phe) preferentially protected cerebral autoregulation in females but not males after TBI. We hypothesized that, in contrast to the newborn, Phe prevents impairment of autoregulation and tissue injury following TBI in both sexes of older pigs...
March 29, 2017: Pediatric Research
https://www.readbyqxmd.com/read/28331079/characterization-and-vaccine-potential-of-membrane-vesicles-produced-by-francisella-noatunensis-subsp-orientalis-in-an-adult-zebrafish-model
#17
Leidy Lagos, Julia I Tandberg, Urska Repnik, Preben Boysen, Erik Ropstad, Deepa Varkey, Ian T Paulsen, Hanne C Winther-Larsen
Vaccine development against extracellular bacteria has been important for the sustainability of the aquaculture industry. In contrast, infections with intracellular pathogens remain largely an unresolved problem. Francisella noatunensis subsp. orientalis is a Gram-negative, facultative intracellular bacterium that causes the disease francisellosis in fish. Francisellosis is commonly characterized as a chronic granulomatous disease with high morbidity and can result in high mortality depending on the host. In this study, we explored the potential of bacterial membrane vesicles (MVs) as a vaccine agent against F...
May 2017: Clinical and Vaccine Immunology: CVI
https://www.readbyqxmd.com/read/28315455/7-8-dihydroxyflavone-facilitates-the-action-exercise-to-restore-plasticity-and-functionality-implications-for-early-brain-trauma-recovery
#18
Gokul Krishna, Rahul Agrawal, Yumei Zhuang, Zhe Ying, Afshin Paydar, Neil G Harris, Luiz Fernando F Royes, Fernando Gomez-Pinilla
Metabolic dysfunction accompanying traumatic brain injury (TBI) severely impairs the ability of injured neurons to comply with functional demands. This limits the success of rehabilitative strategies by compromising brain plasticity and function, and highlights the need for early interventions to promote energy homeostasis. We sought to examine whether the TrkB agonist, 7,8-dihydroxyflavone (7,8-DHF) normalizes brain energy deficits and reestablishes more normal patterns of functional connectivity, while enhancing the effects of exercise during post-TBI period...
March 14, 2017: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/28303450/dr%C3%AE-1-mog-35-55-treatment-reduces-lesion-volumes-and-improves-neurological-deficits-after-traumatic-brain-injury
#19
Liu Yang, Zhijia Liu, Honglei Ren, Lei Zhang, Siman Gao, Li Ren, Zhi Chai, Roberto Meza-Romero, Gil Benedek, Arthur A Vandenbark, Halina Offner, Minshu Li
Traumatic brain injury (TBI) results in severe neurological impairments without effective treatments. Inflammation appears to be an important contributor to key pathogenic events such as secondary brain injury following TBI and therefore serves as a promising target for novel therapies. We have recently demonstrated the ability of a molecular construct comprised of the human leukocyte antigen (HLA)-DRα1 domain linked covalently to mouse (m)MOG-35-55 peptide (DRα1-MOG-35-55 construct) to reduce CNS inflammation and tissue injury in animal models of multiple sclerosis and ischemic stroke...
March 16, 2017: Metabolic Brain Disease
https://www.readbyqxmd.com/read/28289563/persistent-erectile-dysfunction-in-men-exposed-to-the-5%C3%AE-reductase-inhibitors-finasteride-or-dutasteride
#20
Tina Kiguradze, William H Temps, Paul R Yarnold, John Cashy, Robert E Brannigan, Beatrice Nardone, Giuseppe Micali, Dennis Paul West, Steven M Belknap
IMPORTANCE: Case reports describe persistent erectile dysfunction (PED) associated with exposure to 5α-reductase inhibitors (5α-RIs). Clinical trial reports and the manufacturers' full prescribing information (FPI) for finasteride and dutasteride state that risk of sexual adverse effects is not increased by longer duration of 5α-RI exposure and that sexual adverse effects of 5α-RIs resolve in men who discontinue exposure. OBJECTIVE: Our chief objective was to assess whether longer duration of 5α-RI exposure increases risk of PED, independent of age and other known risk factors...
2017: PeerJ
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