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https://www.readbyqxmd.com/read/29775205/modified-device-for-fluid-percussion-injury-in-rodents
#1
Wei Ouyang, Wenhui Wu, Zhiheng Fan, Jihui Wang, Huiju Pan, Weibin Yang
Fluid percussion (FP) injury model is a popular animal model of traumatic brain injury (TBI), but still there are some issues need to be addressed. To increase the validity and reliability of this technique, we adapted the FP device using electromagnetic protractor, stainless-steel cylinder, changing pressure transducer position, and foam pads to adjust the parameters of FP pulse. Besides, the adjusted FP device is more automatic. The FP pulse is promptly measured and displayed in a graphic user interface software...
May 18, 2018: Journal of Neuroscience Research
https://www.readbyqxmd.com/read/29755549/evaluation-of-diabetogenic-mechanism-of-high-fat-diet-in-combination-with-arsenic-exposure-in-male-mice
#2
Akram Ahangarpour, Soheila Alboghobeish, Mohsen Rezaei, Mohammad Javad Khodayar, Ali Akbar Oroojan, Marzieh Zainvand
Obesity is a main reason of type 2 diabetes and also chronic exposure to arsenic (As) can produce diabetic symptoms. In previous studies, the association between high-fat diet and arsenic in the incidence of diabetes was found, but the role of beta cells activity, liver mitochondrial oxidative stress, and hepatic enzymes (leptin, adiponectin and beta amylase) was unclear. Thus, present study was conducted to evaluate the diabetogenic mechanism of arsenic followed by concomitant administration of high-fat diet (HFD) in male mice...
2018: Iranian Journal of Pharmaceutical Research: IJPR
https://www.readbyqxmd.com/read/29751560/direct-reflectance-measurements-from-drones-sensor-absolute-radiometric-calibration-and-system-tests-for-forest-reflectance-characterization
#3
Teemu Hakala, Lauri Markelin, Eija Honkavaara, Barry Scott, Theo Theocharous, Olli Nevalainen, Roope Näsi, Juha Suomalainen, Niko Viljanen, Claire Greenwell, Nigel Fox
Drone-based remote sensing has evolved rapidly in recent years. Miniaturized hyperspectral imaging sensors are becoming more common as they provide more abundant information of the object compared to traditional cameras. Reflectance is a physically defined object property and therefore often preferred output of the remote sensing data capture to be used in the further processes. Absolute calibration of the sensor provides a possibility for physical modelling of the imaging process and enables efficient procedures for reflectance correction...
May 3, 2018: Sensors
https://www.readbyqxmd.com/read/29747671/metabolic-acidosis-as-food-protein-induced-enterocolitis-syndrome-fpies-onset-in-a-newborn
#4
Antonella Peduto, Mario Rocca, Cinzia De Maio, Federica Gallarotti, Giulia Pomero, Paolo Gancia
BACKGROUND: FPIES (Food Protein Induced Eneterolitis Syndrome) is a rare non IgE- mediated food allergy, usually affecting infants and children after first months of life. Clinical presentation is heterogeneous, usually characterised by repetitive vomiting and diarrhoea, lethargy, failure to thrive until to dehydration with hypotension and shock. The diagnosis is based on clinical criteria, after excludind other hypothetical conditions. Early recognition of FPIES is essential to set a correct dietatay management that is resolving for the patient...
May 10, 2018: Italian Journal of Pediatrics
https://www.readbyqxmd.com/read/29742725/relationship-between-foot-posture-and-dental-malocclusions-in-children-aged-6-to-9-years-a-cross-sectional-study
#5
Ana Marchena-Rodríguez, Noelia Moreno-Morales, Edith Ramírez-Parga, María Teresa Labajo-Manzanares, Alejandro Luque-Suárez, Gabriel Gijon-Nogueron
The aim of this study was to determine the association, if any, between foot posture and dental malocclusions in the anteroposterior plane, in children.The study population consisted of 189 children (95 boys and 94 girls) aged 6 to 9 years. In every case, previous informed consent was requested and obtained from the parent/guardian and the study was approved by the Ethics Committee of the University of Málaga (CEUMA 26/2015H).This observational, descriptive, cross-sectional analysis is based on a study population (STROBE)...
May 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29682429/when-why-and-how-foot-orthoses-fos-should-be-prescribed-for-children-with-flexible-pes-planus-a-delphi-survey-of-podiatrists
#6
Sindhrani Dars, Hayley Uden, Saravana Kumar, Helen A Banwell
Background: Flexible pes planus (flat feet) in children is a common reason parents and caregivers seek health professionals consult and a frequent reason podiatrists prescribe foot orthoses. Yet no universal agreement exists on the diagnosis of this condition, or when and how foot orthoses should be prescribed. The aim of this study was to garner consensus and agreement among podiatrists on the use of FOs for paediatric flexible pes planus. Methods: A three round Delphi consensus survey was undertaken with 15 podiatry experts from Australia, New Zealand and the United Kingdom...
2018: PeerJ
https://www.readbyqxmd.com/read/29676680/midline-central-fluid-percussion-model-of-traumatic-brain-injury-in-pediatric-and-adolescent-rats
#7
Rachel K Rowe, Jordan L Harrison, Timothy W Ellis, P David Adelson, Jonathan Lifshitz
OBJECTIVE Experimental traumatic brain injury (TBI) models hold significant validity to the human condition, with each model replicating a subset of clinical features and symptoms. TBI is the leading cause of mortality and morbidity in children and teenagers; thus, it is critical to develop preclinical models of these ages to test emerging treatments. Midline fluid percussion injury (FPI) might best represent mild and diffuse clinical brain injury because of the acute behavioral deficits, the late onset of behavioral morbidities, and the absence of gross histopathology...
April 20, 2018: Journal of Neurosurgery. Pediatrics
https://www.readbyqxmd.com/read/29628253/interactions-between-fava-bean-protein-and-dextrans-produced-by-leuconostoc-pseudomesenteroides-dsm-20193-and-weissella-cibaria-sj-1b
#8
Yan Xu, Leena Pitkänen, Ndegwa Henry Maina, Rossana Coda, Kati Katina, Maija Tenkanen
The aim of this study was to study the interactions between dextran and fava bean protein. Two dextrans produced by Leuconostoc pseudomesenteroides DSM 20193 and Weissella cibaria Sj 1b were purified and mixed with fava bean protein isolate (FPI) in water or in different buffers. The two isolated dextrans presented a typical dextran structure, mainly α-(1 → 6) linkages (above 95%) and few α-(1 → 3) branches, but they differed in molar mass and conformation. Dry-heating incubation of FPI and dextran mixture facilitated the conjugation of dextran to FPI through the Maillard reaction...
June 15, 2018: Carbohydrate Polymers
https://www.readbyqxmd.com/read/29623454/food-protein-induced-enterocolitis-syndrome-fpies-review-of-recent-guidelines
#9
REVIEW
Sheeba Cherian, Pooja Varshney
PURPOSE OF REVIEW: To increase understanding of food protein-induced enterocolitis syndrome (FPIES), a non-immunoglobulin E (IgE)-mediated reaction to food, by reviewing a growing body of literature, including recently published international consensus guidelines. RECENT FINDINGS: FPIES primarily affects infants and young children and is characterized by the delayed onset of gastrointestinal symptoms, predominantly repetitive vomiting, in response to a trigger food...
April 6, 2018: Current Allergy and Asthma Reports
https://www.readbyqxmd.com/read/29622825/gastrointestinal-food-allergy-in-ghanaian-children-a-case-series
#10
Taiba J Afaa, Adwoa Ka Afrane, Victor Etwire
Background: Food allergy is an adverse health effect arising from a specific immune response that occurs reproducibly on exposure to a given food. Food allergies are classified into three types: Ig(immunoglobulin)E mediated, mixed IgE and cell mediated and cell-mediated non IgE mediated. Gastrointestinal (GIT) food allergy has classically encompassed a number of different clinical entities: food protein-induced enterocolitis syndrome (FPIES), food protein-induced proctocolitis (FPIP), food protein-induced enteropathy and eosinophilic gastrointestinal disorders (EGID)...
September 2017: Ghana Medical Journal
https://www.readbyqxmd.com/read/29604776/hypersonic-force-measurements-using-internal-balance-based-on-optical-micromachined-fabry-perot-interferometry
#11
Huacheng Qiu, Fu Min, Shaolong Zhong, Xin Song, Yanguang Yang
Force measurements using wind tunnel balance are necessary for determining a variety of aerodynamic performance parameters, while the harsh environment in hypersonic flows requires that the measurement instrument should be reliable and robust, in against strong electromagnetic interference, high vacuum, or metal (oxide) dusts. In this paper, we demonstrated a three-component internal balance for hypersonic aerodynamic force measurements, using novel optical micromachined Fabry-Perot interferometric (FPI) strain gauges as sensing elements...
March 2018: Review of Scientific Instruments
https://www.readbyqxmd.com/read/29604734/a-fabry-p%C3%A3-rot-interferometer-with-wire-grid-polarizers-as-beamsplitters-at-terahertz-frequencies
#12
H Harrison, A J Lancaster, I V Konoplev, G Doucas, A Aryshev, M Shevelev, N Terunuma, J Urakawa, P G Huggard
The design of a compact Fabry-Pérot interferometer (FPi) and results of the experimental studies carried out using the device are presented. Our FPi uses freestanding wire-grid polarizers (WGPs) as beamsplitters and is suitable for use at terahertz (THz) frequencies. The FPi was studied at the LUCX facility, KEK, Japan, and an 8 MeV linear electron accelerator was used to generate coherent Smith-Purcell radiation. The FPi was designed to be easy to align and reposition for experiments at linear accelerator facilities...
March 2018: Review of Scientific Instruments
https://www.readbyqxmd.com/read/29604617/foot-posture-development-in-children-aged-5-to11-years-a-three-year-prospective-study
#13
Alfonso Martínez-Nova, Gabriel Gijón-Noguerón, Pilar Alfageme-García, Jesús Montes-Alguacil, Angela Margaret Evans
BACKGROUND: The paediatric flatfoot is a common presentation but it is unclear whether the condition will resolve on its own as the child gets older or whether treatment is required. Therefore, the study objective was to evaluate paediatric foot posture, and anthropometry, in children at two time points, three years apart. MATERIAL AND METHODS: A sample of 1032 healthy children (505 boys, 527 girls; aged 5-11 years) was recruited for foot posture index (FPI) and anthropometry assessment (weight, height and body mass index, BMI)...
March 26, 2018: Gait & Posture
https://www.readbyqxmd.com/read/29590371/somatostatin-analogs-and-glucose-metabolism-in-acromegaly-a-meta-analysis-of-prospective-interventional-studies
#14
Alessia Cozzolino, Tiziana Feola, Ilaria Simonelli, Giulia Puliani, Carlotta Pozza, Elisa Giannetta, Daniele Gianfrilli, Patrizio Pasqualetti, Andrea Lenzi, Andrea M Isidori
Introduction: Somatostatin analogs (SSAs) effectivelycontrol growth hormone secretion in first and second line treatmentof acromegaly. Their effect onglucose metabolism is still debated. Aim: to address the following questions: 1) Do SSAs affect fasting plasma glucose (FPG), fasting plasma insulin (FPI), glycosylated hemoglobin (HbA1c), glucose load (2h-OGTT), HOMA-I, HOMA-β, triglycerides (TGD), weight (W) or body mass index (BMI)? 2) Do lanreotide (LAN) and octreotide LAR (OCT) affect metabolism differently? 3)Does their effect depend on disease control? Methods: We performed a meta-analysis of prospective interventional trialstreating acromegaly with SSAs...
March 23, 2018: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29574363/effect-of-static-foot-posture-on-the-dynamic-stiffness-of-foot-joints-during-walking
#15
E Sanchis-Sales, J L Sancho-Bru, A Roda-Sales, J Pascual-Huerta
BACKGROUND: The static foot posture has been related to the development of lower limb injuries. RESEARCH QUESTION: This study aimed to investigate the dynamic stiffness of foot joints during gait in the sagittal plane to understand the role of the static foot posture in the development of injuries. METHODS: Seventy healthy adult male subjects with different static postures, assessed by the Foot Posture Index (FPI) (30 normal, 20 highly pronated and 20 highly supinated), were recruited...
March 17, 2018: Gait & Posture
https://www.readbyqxmd.com/read/29560994/fe-3-o-4-decorated-graphene-assembled-porous-carbon-nanocomposite-for-ammonia-sensing-study-using-an-optical-fiber-fabry-perot-interferometer
#16
Dnyandeo Pawar, B V Bhaskara Rao, S N Kale
A porous graphene-coated optical fiber Fabry-Perot interferometer (G-FPI) and Fe3O4-graphene nanocomposite coated Fabry-Perot interferometer (FG-FPI) have been investigated and compared for the detection of ammonia gas at room temperature. The sensor probes were subjected to ammonia concentrations varying from 1.5 ppm to 150 ppm. An increased sensitivity was observed for FG-FPI (36 pm ppm-1) when compared with that of G-FPI (25 pm ppm-1). The observed sensor detection limits for FG-FPI and G-FPI were around 7 and 10 ppb, respectively...
March 21, 2018: Analyst
https://www.readbyqxmd.com/read/29554045/adenosine-lidocaine-and-mg2-alm-resuscitation-fluid-protects-against-experimental-traumatic-brain-injury
#17
Hayley L Letson, Geoffrey P Dobson
BACKGROUND: Currently no drug therapy prevents secondary injury progression after TBI. Our aim was to investigate the effects of small-volume intravenous adenosine, lidocaine and Mg (ALM) resuscitation fluid after moderate-TBI in a rat fluid-percussion injury model. METHODS: Anesthetized, mechanically-ventilated male Sprague-Dawley rats (449±5g) were randomly assigned to one of four groups: 1) Sham (craniotomy without TBI), 2) No-Treatment, 3) Saline-controls or 4) ALM therapy (all n=16)...
March 16, 2018: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/29545916/profound-deficits-in-hippocampal-synaptic-plasticity-after-traumatic-brain-injury-and-seizure-is-ameliorated-by-prophylactic-levetiracetam
#18
Yuan-Hao Chen, Tung-Tai Kuo, Eagle Yi-Kung Huang, Barry J Hoffer, Yu-Ching Chou, Yung-Hsiao Chiang, Hsin-I Ma, Jonathan P Miller
Aim: To determine the precise effects of post-traumatic seizure activity on hippocampal processes, we induced seizures at various intervals after traumatic brain injury (TBI) and analyzed plasticity at CA1 Schaffer collateral synapses. Material and Methods: Rats were initially separated into two groups; one exposed solely to fluid percussion injury (FPI) at 2 Psi and the other only receiving kainic acid (KA)-induced seizures without FPI. Electrophysiological (ePhys) studies including paired-pulse stimulation for short-term presynaptic plasticity and long-term potentiation (LTP) of CA1 Schaffer collateral synapses of the hippocampus for post-synaptic function survey were followed at post-event 1 hour, 3 and 7 days respectively...
February 20, 2018: Oncotarget
https://www.readbyqxmd.com/read/29544118/automated-retinal-nerve-fiber-layer-defect-detection-using-fundus-imaging-in-glaucoma
#19
Rashmi Panda, N B Puhan, Aparna Rao, Debananda Padhy, Ganapati Panda
Retinal nerve fiber layer defect (RNFLD) provides an early objective evidence of structural changes in glaucoma. RNFLD detection is currently carried out using imaging modalities like OCT and GDx which are expensive for routine practice. In this regard, we propose a novel automatic method for RNFLD detection and angular width quantification using cost effective redfree fundus images to be practically useful for computer-assisted glaucoma risk assessment. After blood vessel inpainting and CLAHE based contrast enhancement, the initial boundary pixels are identified by local minima analysis of the 1-D intensity profiles on concentric circles...
June 2018: Computerized Medical Imaging and Graphics: the Official Journal of the Computerized Medical Imaging Society
https://www.readbyqxmd.com/read/29529734/refractive-index-modified-dot-fabry-perot-fiber-probe-fabricated-by-femtosecond-laser-for-high-temperature-sensing
#20
Pengcheng Chen, Xuewen Shu
An optical fiber Fabry-Perot probe sensor for high-temperature measurement is proposed and demonstrated, which is fabricated by inducing a refractive-index-modified-dot (RIMD) in the fiber core near the end of a standard single mode fiber (SMF) using a femtosecond laser. The RIMD and the SMF end faces form a Fabry-Perot interferometer (FPI) with a high-quality interference fringe visibility (>20dB). As a high-temperature sensor, such an FPI exhibits a sensitivity of 13.9pm/°C and 18.6pm/°C in the range of 100-500°Cand 500-1000°C,respectively...
March 5, 2018: Optics Express
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