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Rashmi Panda, N B Puhan, Aparna Rao, Debananda Padhy, Ganapati Panda
Retinal nerve fiber layer defect (RNFLD) provides an early objective evidence of structural changes in glaucoma. RNFLD detection is currently carried out using imaging modalities like OCT and GDx which are expensive for routine practice. In this regard, we propose a novel automatic method for RNFLD detection and angular width quantification using cost effective redfree fundus images to be practically useful for computer-assisted glaucoma risk assessment. After blood vessel inpainting and CLAHE based contrast enhancement, the initial boundary pixels are identified by local minima analysis of the 1-D intensity profiles on concentric circles...
March 6, 2018: Computerized Medical Imaging and Graphics: the Official Journal of the Computerized Medical Imaging Society
Pengcheng Chen, Xuewen Shu
An optical fiber Fabry-Perot probe sensor for high-temperature measurement is proposed and demonstrated, which is fabricated by inducing a refractive-index-modified-dot (RIMD) in the fiber core near the end of a standard single mode fiber (SMF) using a femtosecond laser. The RIMD and the SMF end faces form a Fabry-Perot interferometer (FPI) with a high-quality interference fringe visibility (>20dB). As a high-temperature sensor, such an FPI exhibits a sensitivity of 13.9pm/°C and 18.6pm/°C in the range of 100-500°Cand 500-1000°C,respectively...
March 5, 2018: Optics Express
Yuan-Hao Chen, Tung-Tai Kuo, Eagle Yi-Kung Huang, Yu-Ching Chou, Yung-Hsiao Chiang, Barry J Hoffer, Jonathon Miller
Background: Traumatic brain injury is associated with substantial alterations in reward processing, but underlying mechanisms are controversial. Objective: A better understanding of alterations in dopamine (DA) release patterns from the dorsal striatum and nucleus accumbens shell (NAc) may provide insights into posttraumatic reward pathology. Materials and Methods: The patterns of DA release with or without exposure to nicotine in brain slices with striatum and NAc, isolated from Sprague-Dawley rats with 6 psi fluid percussion (FPI) or sham injury were analysis by using fast-scan cyclic voltammetry...
February 9, 2018: Oncotarget
M Siller, E Hotez, M Swanson, A Delavenne, T Hutman, M Sigman
Family-centered parent coaching interventions in autism strive to encourage family engagement and support parent reflection and self-evaluation. This includes the parents' capacity to: (1) carefully observe the child's behavior; (2) reflect upon the child's thoughts, motives, and feelings; (3) consider links between the child's internal experiences and observable behavior; and (4) grapple with the complex interplay among the child's experiences and behaviors, contextual factors, parenting strategies, as well as parental goals and emotions...
March 7, 2018: Attachment & Human Development
Eva Lopezosa-Reca, Gabriel Gijon-Nogueron, Irene Garcia-Paya, Ana Belen Ortega-Avila
This aim of this study is to observe the differences in foot posture and the angle of the knee according to different physical activities. Seventy-eight football players and 72 swimmers were recruited, and in each case a foot posture analysis, based on the foot posture index (FPI), was conducted and the Q angle of the knee was determined. The following mean values were obtained for the lower extremities: in the swimmers, FPI 6.45 ± 2.04 and Q angle 15.38º ± 3.79º. In the footballers, FPI 2.23 ± 1.72 and Q angle 13...
March 4, 2018: Research in Sports Medicine
Shyam R Joshi, J Andrew Bird
No abstract text is available yet for this article.
February 23, 2018: Annals of Allergy, Asthma & Immunology
Pavla Stojkova, Petra Spidlova, Juraj Lenco, Helena Rehulkova, Lucie Kratka, Jiri Stulik
The nucleoid-associated HU proteins are small abundant DNA-binding proteins in bacterial cell which play an important role in the initiation of DNA replication, cell division, SOS response, control of gene expression and recombination. HU proteins bind to double stranded DNA non-specifically, but they exhibit high affinity to abnormal DNA structures as four-way junctions, gaps or nicks, which are generated during DNA damage. In many pathogens HU proteins regulate expression of genes involved in metabolism and virulence...
February 23, 2018: Virulence
S Miceli Sopo, C Fantacci, G Bersani, A Romano, L Liotti, S Monaco
Food protein induced enterocolitis syndrome (FPIES) is classified as non-IgE-mediated or cell-mediated food allergy, although there is an atypical phenotype so defined for the presence of specific IgEs. All diagnostic criteria for FPIES include the absence of skin or respiratory symptoms of IgE-mediated type. We present four cases that suggest that specific IgEs may have a pathogenic role, resulting in the existence of different FPIES phenotypes. This could be important from a diagnostic and therapeutic point of view...
February 19, 2018: Allergologia et Immunopathologia
S Miceli Sopo, G Bersani, C Fantacci, A Romano, S Monaco
Food protein-induced enterocolitis syndrome (FPIES) is a non IgE-mediated gastrointestinal food allergic disorder. Some diagnostic criteria have been published for acute FPIES. Of course, they are not all the same, so the clinician must choose which ones to adopt for his/her clinical practice. We present here a brief review of these criteria and, through two clinical cases, show how the choice of one or the other can change the diagnostic destiny of a child with suspect FPIES.
February 15, 2018: Allergologia et Immunopathologia
Nicole Hausser, Kathia Johnson, Margaret A Parsley, Jutatip Guptarak, Heidi Spratt, Stacy L Sell
With the increasing incidence of traumatic brain injury (TBI) in both civilian and military populations, TBI is now considered a chronic disease; however, few studies have investigated the long-term effects of injury in rodent models of TBI. Shown here are behavioral measures that are well-established in TBI research for times early after injury, such as two weeks, until two months. Some of these methods have previously been used at later times after injury, up to one year, but by very few laboratories. The methods demonstrated here are a short neurological assessment to test reflexes, a Beam-Balance to test balance, a Beam-Walk to test balance and motor coordination, and a working memory version of the Morris water maze that can be sensitive to deficits in reference memory...
January 30, 2018: Journal of Visualized Experiments: JoVE
Andreia Ribeiro, Diana Moreira, Cristina Costa, Isabel Pinto Pais
Food protein-induced enterocolitis syndrome (FPIES) is a non-IgE-mediated gastrointestinal food hypersensitivity triggered by food proteins. It may present acutely, with repetitive vomiting, diarrhoea and lethargy leading to dehydration and eventually shock or insidiously with intermittent emesis, chronic diarrhoea or failure to thrive. We describe a paediatric male patient with recurrent sepsis-like episodes of fever, lethargy, ashen-grey skin colouration and vomiting followed by diarrhoea. These episodes were triggered by cow's milk formula and grains...
February 8, 2018: BMJ Case Reports
Mariana R C Aquino, Bruna S Avelar, Paula L Silva, Juliana M Ocarino, Renan A Resende
BACKGROUND: Previous studies have suggested that the Foot Posture Index (FPI-6) is valid and reliable to evaluate foot posture of adults and children. However, studies with adults had some important limitations. In addition, it is not clear if FPI-6 is reliable for older adults. Variations in foot structure, such as edema, bone callosity and bunions, are more frequent in older adults, which may compromise FPI-6 reliability for this population. OBJECTIVES: To investigate test-retest and inter-rater reliability of FPI-6 total and individual scores for the assessment of foot posture of adults and older adults...
February 6, 2018: Musculoskeletal Science & Practice
Wen-Ge Xie, Ya-Nan Zhang, Peng-Zhao Wang, Jian-Zhang Wang
A review for optical fiber sensors based on fiber ring laser (FRL) demodulation technology is presented. The review focuses on the principles, main structures, and the sensing performances of different kinds of optical fiber sensors based on FRLs. First of all, the theory background of the sensors has been discussed. Secondly, four different types of sensors are described and compared, which includes Mach-Zehnder interferometer (MZI) typed sensors, Fabry-Perot interferometer (FPI) typed sensors, Sagnac typed sensors, and fiber Bragg grating (FBG) typed sensors...
February 8, 2018: Sensors
Salvador Diaz-Miguel, Eva Lopezosa-Reca, Salomon Benhamu-Benhamu, Ana Belen Ortega-Avila, Raquel García-De-La-Peña, Gabriel Gijon-Nogueron
BACKGROUND: Physical activity during childhood can be beneficial in the long term. However, this practice can influence the child's physiological development. The aim of this study was to determine whether the practice of soccer, in moderation, could be a risk factor for the inadequate development of the lower limb. METHODS: The study group was composed of 115 children, of whom 59 (mean age 8.03±0.89years) practised soccer 3 times a week and had a positive Physical Activity Questionnaire for Adolescents (PAQ-A) score, while a further 56 (mean age 7...
November 17, 2017: Foot
Salih Angin, Karen J Mickle, Christopher J Nester
BACKGROUND: The plantar foot muscles and plantar fascia differ between different foot postures. However, how each individual plantar structure contribute to foot posture has not been explored. The purpose of this study was to investigate the associations between static foot posture and morphology of plantar foot muscles and plantar fascia and thus the contributions of these structures to static foot posture. METHODS: A total of 111 participants were recruited, 43 were classified as having pes planus and 68 as having normal foot posture using Foot Posture Index assessment tool...
January 27, 2018: Gait & Posture
Vandana Gupta, Sameeksha Mishra, Supriya Mishra, Sandeep Kumar, Vani Gupta
Leptin and adiponectin play an important role in the regulation of body weight and energy homeostasis. The purpose of the present study was to ascertain the relationship between leptin to adiponectin ratio (L:A) and metabolic risk factors in postmenopausal women.This is a cross sectional case-control study. A total of 523 postmenopausal women were recruited for the study 270 postmenopausal women with metabolic syndrome and 253 apparently healthy control postmenopausal women without metabolic syndrome. Biochemical and Anthropometrical parameters were measured...
February 2, 2018: Immunology Letters
M I Petrosino, A Scaparrotta, P Di Filippo, M Attanasi, S Di Pillo, F Chiarelli, A Mohn
Food protein-induced enterocolitis syndrome (FPIES) is an under-recognized and frequently misdiagnosed non-IgE mediated food allergy syndrome. Affected infants show gastrointestinal symptoms few hours after ingestion of the incriminating food. Pathophysiology of FPIES has not yet been clearly defined and needs further characterization. The common allergy tests are not helpful for this disorder and tests for food specific IgE are usually negative. A diagnostic oral food challenge (OFC) is the method to confirm the diagnosis of FPIES...
November 24, 2017: European Annals of Allergy and Clinical Immunology
Edgar Geissner, Anne Huetteroth
The Beck Anxiety Inventory (BAI) is available in German. Apart from data in its manual, there are no further reports on the psychometric properties of this questionnaire and on its suitability for clinical use in Germany. This study therefore offers an independent investigation into the psychometrics as well as the clinical characteristics of the BAI. Three samples with n=145, n=90, and n=174 comprised inpatients diagnosed with anxiety disorders and treated in a large psychosomatic hospital. In addition to the BAI, the clinician rating Hamilton Anxiety Scale (HamA), the State-Trait-Anxiety Inventory (STAI) as well as the two anxiety subscales of the Symptom Checklist 90 (SCL 90) were used to establish convergent validity...
January 19, 2018: Psychotherapie, Psychosomatik, Medizinische Psychologie
S Miceli Sopo, C Fantacci, G Bersani, A Romano, S Monaco
We describe two case reports presenting some novel information on fish FPIES. Fish FPIES to one fish does not always start at the same time to other fish. Additionally, development of tolerance to the index fish do not necessarily imply tolerance to other reactive fish. This reflects on the best management of children with FPIES fish.
January 12, 2018: Allergologia et Immunopathologia
Zhenshi Chen, Songsong Xiong, Shecheng Gao, Hui Zhang, Lei Wan, Xincheng Huang, Bingsen Huang, Yuanhua Feng, Weiping Liu, Zhaohui Li
A miniaturized tip Fabry-Perot interferometer (tip-FPI) is proposed for high-temperature sensing. It is simply fabricated for the first time by splicing a short length of microfiber (MF) to the cleaved end of a standard single mode fiber (SMF) with precise control of the relative cross section position. Such a MF acts as a Fabry-Perot (FP) cavity and serves as a tip sensor. A change in temperature modifies the length and refractive index of the FP cavity, and then a corresponding change in the reflected interference spectrum can be observed...
January 12, 2018: Sensors
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