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JOURNAL ARTICLE
Tamara Teodoro Araujo, Aline Dionizio, Thamyris Souza Carvalho, Chelsea Maria Vilas Boas Feitosa, Mariele Vertuan, João Victor Frazão Câmara, Flavio Henrique-Silva, Reinaldo Marchetto, Marcos Roberto Chiaratti, Angélica Camargo Santos, Lindomar Oliveira Alves, Milene Ferro, Marília Afonso Rabelo Buzalaf
OBJECTIVE: This study was designed in two-legs. In the in vivo, we explored the potential of a rinse solution containing a combination (Comb) of 0.1 mg/mL CaneCPI-5 (sugarcane-derive cystatin), 1.88 × 10- 5 M StN15 (statherin-derived peptide) and 1.0 mg/mL hemoglobin (Hb) to change the protein profile of the acquired enamel pellicle(AEP) and the microbiome of the enamel biofilm. The in vitro, was designed to reveal the effects of Comb on the viability and bacterial composition of the microcosm biofilm, as well as on enamel demineralization...
April 20, 2024: Clinical Oral Investigations
#2
JOURNAL ARTICLE
Alessia Favaron, Bart Hens, Maiara Montanha, Mark McAllister, Irena Tomaszewska, Shaimaa Moustafa, Marília Alvarenga de Oliveira, Abdul W Basit, Mine Orlu
Upadacitinib, classified as a highly soluble drug, is commercially marketed as RINVOQ®, an modified-release formulation incorporating hydroxypropyl methylcellulose as a matrix system to target extended release throughout the gastrointestinal (GI) tract. Our study aimed to explore how drug release will occur throughout the GI tract using a plethora of in vitro and in silico tools. We built a Physiologically-Based Pharmacokinetic (PBPK) model in GastroPlus™ to predict the systemic concentrations of the drug when administered using in vitro dissolution profiles as input to drive luminal dissolution...
April 17, 2024: Journal of Controlled Release
#3
REVIEW
Rafael Caetano da Silva, Halley Caixeta Oliveira, Abir U Igamberdiev, Claudio Stasolla, Marilia Gaspar
Nitrogen (N) is an essential nutrient for plants, and the sources from which it is obtained can differently affect their entire development as well as stress responses. Distinct inorganic N sources (nitrate and ammonium) can lead to fluctuations in the nitric oxide (NO) levels and thus interfere with nitric oxide (NO)-mediated responses. These could lead to changes in reactive oxygen species (ROS) homeostasis, hormone synthesis and signaling, and post-translational modifications of key proteins. As the consensus suggests that NO is primarily synthesized in the reductive pathways involving nitrate and nitrite reduction, it is expected that plants grown in a nitrate-enriched environment will produce more NO than those exposed to ammonium...
March 29, 2024: Journal of Plant Physiology
#4
JOURNAL ARTICLE
Luciana de Souza Santos, Marília Harumi Higuchi Dos Santos Rehder, Marcelo Vailati Negrao, Beatriz R Goes-Santos, Edgar Toschi-Dias, Camila Jordão Paixão, Ursula Urias, Natali Schiavo Giannetti, Ludhmila A Hajjar, Roberto Kalil Filho, Carlos E Negrão
BACKGROUND: It is unclear whether muscle blood flow (MBF) is altered in long-term Hodgkin Lymphoma (HL) survivors. We test the hypothesis that: 1) MBF response during mental stress (MS) is impaired in long-term HL survivors; 2) Aerobic exercise training combined with local strength exercise (ET) restores MBF responses during MS in these survivors. METHODS: Eighteen 5-year HL survivors and 10 aged-paired healthy subjects (HC) were studied. Twenty HL survivors were randomly divided into two groups: Exercise-trained (HLT, n=10) and untrained (HLUT, n=10)...
April 19, 2024: American Journal of Physiology. Heart and Circulatory Physiology
#5
JOURNAL ARTICLE
Marcela Albuquerque de Oliveira, Marília Gabriela Muniz Arruda, Nabuêr Francieli da Silva, Rômulo Carlos Dantas da Cruz, Suelen Cristina Lourenço de Barros, Marcilene Souza da Silva, Talita Giselly Dos Santos Souza, Erwelly Barros de Oliveira, Cristiano Aparecido Chagas, Jaciana Dos Santos Aguiar, Alisson Macário de Oliveira, Roberta Jeane Bezerra Jorge, Ivone Antonia de Souza
ETHNOPHARMACOLOGICAL RELEVANCE: Croton argyrophyllus Kunth., commonly known as "marmeleiro" or "cassetinga," is widely distributed in the Brazilian Northeast region. Its leaves and flowers are used in traditional medicine as tranquilizers to treat flu and headaches. AIM OF THE STUDY: This study was conducted to determine the chemical composition and toxicological safety of essential oil from C. argyrophyllus leaves using in vitro and in vivo models. MATERIALS AND METHODS: The chemical composition of the essential oil was determined using a gas chromatograph coupled to a mass spectrometer...
April 16, 2024: Journal of Ethnopharmacology
#6
JOURNAL ARTICLE
Oswaldo Yoshimi Tanaka, Marco Akerman, Marília Cristina Prado Louvison, Aylene Bousquat, Nicanor Rodrigues da Silva Pinto, Ana Lígia Passos Meira, Lídia Pereira da Silva Godoi, Ana Paula Chancharulo E Morais Pereira, Sandra Maria Spedo, Monique Batista de Oliveira, Ilana Eshriqui, Marcio Anderson Cardozo Paresque
OBJECTIVE: To recognize elements that facilitated or hindered the PlanificaSUS implementation stages. METHODS: A multiple case study was carried out in four pre-selected health regions in Brazil-Belo Jardim (PE), Fronteira Oeste (RS), Sul-Mato-Grossense (MT) and Valença (BA) using systemic arterial hypertension and maternal and child care as tracer conditions. Participant observation (in regional interagency commissions) and in-depth interviews with key informants from state and municipal management and primary health care and specialized outpatient care service professionals within the project were carried out in these four regions...
2024: Revista de Saúde Pública
#7
JOURNAL ARTICLE
Caio Sampaio, Daniela Alejandra Cusicanqui Méndez, Marília Afonso Rabelo Buzalaf, Juliano Pelim Pessan, Thiago Cruvinel
OBJECTIVE: To assess the effects of arginine, with or without sodium fluoride (NaF; 1,450 ppm), on saliva-derived microcosm biofilms and enamel demineralization. METHODS: Saliva-derived biofilms were grown on bovine enamel blocks in 0.2% sucrose-containing modified McBain medium, according to six experimental groups: control (McBain 0.2%); 2.5% arginine; 8% arginine; NaF; 2.5% arginine with NaF; and 8% arginine with NaF. After 5 days of growth, biofilm viability was assessed by colony-forming units counting, laser scanning confocal microscopy was used to determine biofilm vitality and extracellular polysaccharide (EPS) production, while biofilm metabolism was evaluated using the resazurin assay and lactic acid quantification...
April 13, 2024: Journal of Dentistry
#8
JOURNAL ARTICLE
Marilia Fernandes Bolsanello, Andrea Abreu García, Luciana Xavier da Cruz Lima, Bruno Kneipel Neto, Jetson Lemos Ferreira, Jesualdo Luiz Rossi, Isolda Costa, Ricardo M Souto, Javier Izquierdo
Corrosion processes at cut edges of galvanized steels proceed as highly localized electrochemical reactions between the exposed bulk steel matrix and the protective thin metallic coating of a more electrochemically active material. Scanning microelectrochemical techniques can thus provide the spatially resolved information needed to assess the corrosion initiation and propagation phenomena, yet most methods scan cut edge sections as embedded in insulating resin to achieve a flat surface for scanning purposes...
April 5, 2024: Materials
#9
JOURNAL ARTICLE
Ingridi Camboim Franceschi, Rubem Augusto da Paixão Dornas, Isabel Salgueiro Lermen, Artur Vicente Pfeifer Coelho, Ademir Henrique Vilas Boas, Adriano Garcia Chiarello, Adriano Pereira Paglia, Agnis Cristiane de Souza, Alana Rafaela Borsekowsky, Alessandro Rocha, Alex Bager, Alexander Zaidan de Souza, Alexandre Martins Costa Lopes, Aloysio Souza de Moura, Aluane Silva Ferreira, Alvaro García-Olaechea, Ana Cláudia Delciellos, Ana Elisa de Faria Bacellar, Ana Kellen Nogueira Campelo, Ana Maria Oliveira Paschoal, Anderson Claudino Rolim, André Luiz Ferreira da Silva, Andre Monnerat Lanna, André Pereira da Silva, Andresa Guimarães, Ângela Cardoso, Angelica Soligo Cassol, Anna Ludmilla da Costa-Pinto, Ariel Guilherme Santos do Nascimento, Arthur Soares Fernandes, Aryanne Clyvia, Aureo Banhos Dos Santos, Barbara Lima-Silva, Beatriz de Mello Beisiegel, Beatriz Fernandes Lima Luciano, Bernardo de Faria Leopoldo, Bruna Nunes Krobel, Bruno Busnello Kubiak, Bruno Henrique Saranholi, Bruno Senna Correa, Caio Sant Anna Teixeira, Camila Rezende Ayroza, Camila Righetto Cassano, Camilo Benitez-Riveros, Carla Cristina Gestich, Carla Denise Tedesco, Carla Gheler-Costa, Carla Grasiele Zanin Hegel, Carlito da Silva Evangelista Junior, Carlos Eduardo Morando Faria Ferreira, Carlos Eduardo Viveiros Grelle, Carolina Franco Esteves, Caroline da Costa Espinosa, Caroline Leuchtenberger, Catalina Sanchéz-Lalinde, Cauanne Iglesias Campos Machado, Cecilia Andreazzi, Cecília Bueno, Cecilia Cronemberger de Faria, Claudio Novaes, Cynthia Elisa Widmer, Cyntia Cavalcante Santos, Daniel da Silva Ferraz, Daniel Galiano, Daniela Aparecida Savariz Bôlla, Daniela Behs, Daniele Pereira Rodrigues, Danielle Picão de Melo, Déborah Maria Soares Ramos, Denise Lidório de Mattia, Diego Dias Pavei, Diogo Loretto, Douglas da Silva Huning, Douglas de Matos Dias, Éder Ricardo Paetzhold, Elaine Rios, Eleonore Zulnara Freire Setz, Eliana Cazetta, Emanuel Giovani Cafofo Silva, Emanuelle Pasa, Erica Naomi Saito, Erick Francisco Silva de Aguiar, Érika Paula Castro, Ernesto Bastos Viveiros de Castro, Ezequiel Pedó, Fabiane de Aguiar Pereira, Fábio Bolzan, Fábio de Oliveira Roque, Fábio Dias Mazim, Fábio Henrique Comin, Fábio Maffei, Felipe Bortolotto Peters, Felipe Moreli Fantacini, Felipe Pessoa da Silva, Felipe Santana Machado, Felipe Vélez-Garcia, Fernanda Stussi Duarte Lage, Fernando Araújo Perini, Fernando Camargo Passos, Fernando Carvalho, Fernando Cesar Cascelli de Azevedo, Fernando Ferreira, Fernando Ferreira de Pinho, Flávia Guimarães Chaves, Flavia Regina Miranda, Flavio Henrique Guimarães Rodrigues, Flávio Kulaif Ubaid, Francisco Homem Gabriel, Franco Leandro de Souza, Fred Victor de Oliveira, Gabriel Cupolillo, Gabriela de Araújo Pires Moreira, Gabriela Mette, Gabriela Teixeira Duarte, Gabrielle Beca, Gilberto Corso, Gilmar Perbiche-Neves, Glauber Henrique Borges de Oliveira Souto, Glenda Jéssica da Silva Vilarroel, Graziele O Batista, Guilherme Braga Ferreira, Gustavo Alves da Costa Toledo, Gustavo Senger, Helena de Godoy Bergallo, Hellen Cristina Pinheiro Dos Santos, Humberto Angelo Gazola, Isabel Melo, Ismael Verrastro Brack, Iuri Veríssimo, Ivan Réus Viana, Izabela Costa Laurentino, Jaime Luis Diehl, Jairo José Zocche, Jimi Martins-Silva, João Paulo Gava Just, Jorge José Cherem, Jorge Luiz Nascimento, Jorge Reppold Marinho, José Oliveira Dantas, Jose Roberto de Matos, José Salatiel Rodrigues Pires, Josi Fernanda Cerveira, Juan Ruiz-Esparza, Juliana Paulo da Silva, Juliano André Bogoni, Karina Theodoro Molina, Karla Dayane de Lima Pereira, Karoline Ceron, Kristel de Vleeschouwer, Laís Lautenschlager, Larissa Bailey, Larissa Fornitano, Lilian Elaine Rampim, Lorena Sforza, Luan Gonçalves Bissa, Luca Mattos Santucci, Lucas Gonçalves da Silva, Lucas Neves Perillo, Lucas Ribeiro Correa, Ludmila Hufnagel, Luis Fernando Alberti, Luis Jose Recalde Mello, Luis Renato Rezende Bernardo, Luiz Gustavo Rodrigues Oliveira-Santos, Luiza Neves Guimarães, Maíra Benchimol, Manuela Catharina Twardowschy, Marcela Ferreira-Riveros, Marcelo da Silva, Márcia Maria de Assis Jardim, Marco Aurélio Leite Fontes, Marcos Adriano Tortato, Marcos Tadeu do Nascimento, Margareth Lumy Sekiama, Maria Clara Nascimento-Costa, Maria Ester Bueno Dos Santos, Maria Santina de Castro Morini, Mariana Baldy Nagy-Reis, Mariane da Cruz Kaizer, Mariano José Ribeiro da Silva Sant'Anna, Marilia Teresinha Hartmann, Marina Ochoa Favarini, Marina Oliveira Olivo, Martín Alejandro Montes, Martin Roberto Del Valle Alvaréz, Matheus Feldstein Haddad, Maurício Djalles Costa, Maurício Eduardo Graipel, Mauricio Quoos Konzen, Mauro Galetti, Meyline de Oliveira Souza Almeida, Michel Barros Faria, Micheli Ribeiro Luiz, Michelle Noronha da Matta Baptista, Miguel Ângelo Marini, Milton Cezar Ribeiro, Natalie Olifiers, Natasha Moraes de Albuquerque, Nicolás Cantero, Nivaldo Peroni, Noeli Zanella, Olívia Mendonça-Furtado, Olivier Pays, Orlando Ednei Ferretti, Oscar Rocha-Barbosa, Paloma Marques Santos, Patrícia Menegaz de Farias, Patrício Adriano da Rocha, Paul François Colas-Rosas, Paula Ribeiro-Souza, Paula Ferracioli, Paulo Afonso Hartmann, Paulo de Tarso Zuquim Antas, Paulo Ribeiro, Paulo Tomasi Sarti, Paulo Ivo Mônico, Pedro Volkmer de Castilho, Peônia Brito de Moraes Pereira, Peter Gransden Crawshaw, Pierre-Cyril Renaud, Rafael Spilere Romagna, Rafael Turíbio Moraes de Sousa, Raíssa Soares Spagnol, Raone Beltrão-Mendes, Ravi Fernandes Mariano, Renata Reinoso Rocha, Renata Sousa-Lima, Renata Valls Pagotto, Rhayssa Terra de Faria, Ricardo Corassa Arrais, Ricardo Moratelli, Ricardo Sartorello, Rita de Cassia Bianchi, Roberto de Carvalho Guimarães, Rodrigo Lima Massara, Romulo Theodoro Costa, Rosane Vera Marques, Ruan Márcio Ruas Nunes, Sandra Maria Hartz, Saulo Meneses Silvestre de Sousa, Saulo Ramos Lima, Sergio Lutz Barbosa, Silvia Neri Godoy, Stephen Francis Ferrari, Talita Guimarães de Araújo-Piovezan, Talita Laura Góes, Tatiane Campos Trigo, Thales R O de Freitas, Thiago Bernardes Maccarini, Thiago Marcial de Castro, Thiago Ribas Bella, Tonny Marques de Oliveira Junior, Uslaine Maciel Cunha, Vanessa Tavares Kanaan, Vera Pfannerstill, Victor Siqueira Pimentel, Vilmar Picinatto Filho, Vinícius Nunes Alves, Viviana Rojas-Bonzi, Viviane Mottin, Vlamir José Rocha, Andreas Kindel, Igor Pfeifer Coelho
Camera traps became the main observational method of a myriad of species over large areas. Data sets from camera traps can be used to describe the patterns and monitor the occupancy, abundance, and richness of wildlife, essential information for conservation in times of rapid climate and land-cover changes. Habitat loss and poaching are responsible for historical population losses of mammals in the Atlantic Forest biodiversity hotspot, especially for medium to large-sized species. Here we present a data set from camera trap surveys of medium to large-sized native mammals (>1 kg) across the Atlantic Forest...
April 12, 2024: Ecology
#10
JOURNAL ARTICLE
Andrea Campagner, Marilia Barandas, Duarte Folgado, Hugo Gamboa, Federico Cabitza
In this article we propose a conceptual framework to study ensembles of conformal predictors (CP), that we call Ensemble Predictors (EP). Our approach is inspired by the application of imprecise probabilities in information fusion. Based on the proposed framework, we study, for the first time in the literature, the theoretical properties of CP ensembles in a general setting, by focusing on simple and commonly used possibilistic combination rules. We also illustrate the applicability of the proposed methods in the setting of multivariate time-series classification, showing that these methods provide better performance (in terms of both robustness, conservativeness, accuracy and running time) than both standard classification algorithms and other combination rules proposed in the literature, on a large set of benchmarks from the UCR time series archive...
April 12, 2024: IEEE Transactions on Pattern Analysis and Machine Intelligence
#11
JOURNAL ARTICLE
Marilia Mastrocolla de Almeida Cardoso, Juliana Machado-Rugolo, Lehana Thabane, Naila Camila da Rocha, Abner Mácula Pacheco Barbosa, Denis Satoshi Komoda, Juliana Tereza Coneglian de Almeida, Daniel da Silva Pereira Curado, Silke Anna Theresa Weber, Luis Gustavo Modelli de Andrade
INTRODUCTION: Health technology assessment (HTA) plays a vital role in healthcare decision-making globally, necessitating the identification of key factors impacting evaluation outcomes due to the significant workload faced by HTA agencies. OBJECTIVES: The aim of this study was to predict the approval status of evaluations conducted by the Brazilian Committee for Health Technology Incorporation (CONITEC) using natural language processing (NLP). METHODS: Data encompassing CONITEC's official report summaries from 2012 to 2022...
April 12, 2024: International Journal of Technology Assessment in Health Care
#12
JOURNAL ARTICLE
Jeane de Souza Nogueira, Thamires Rodrigues Gomes, Danielle Angst Secco, Inez Silva de Almeida, Alessandra Saldanha Matheus Fernandes da Costa, Roberta Arnoldi Cobas, Gilson Costados Santos, Marília Brito Gomes, Luís Cristóvão Pôrto
To control immune responses, regulatory CD4+ CD25+ Foxp3+ T cells (Treg) maintain their wide and diverse repertoire through continuous arrival of recent thymic emigrants (RTE). However, during puberty, the activity of RTE starts to decline as a natural process of thymic involution, introducing consequences, not completely described, to the repertoire. Type 1 diabetes (T1D) patients show quantitative and qualitative impairments on the Treg cells. Our aim was to evaluate peripheral Treg and RTE cell frequencies, in T1D patients from two distinct age groups (young and adults) and verify if HLA phenotypes are concomitant associated...
April 9, 2024: Immunology Letters
#13
JOURNAL ARTICLE
Maria Karolina Martins Ferreira, Priscila Cunha Nascimento, Leonardo Oliveira Bittencourt, Giza Hellen Nonato Miranda, Nathalia Carolina Fernandes Fagundes, Fatemeh Vida Zahoori, E Angeles Martinez-Mier, Marília Afonso Rabelo Buzalaf, Rafael Rodrigues Lima
Numerous pre-clinical and observational studies have explored the potential effects of fluoride (F) at varying concentrations on diverse systems and organs. While some have assessed the endocrinological conditions of children and adults, a consensus regarding the interaction between F and the thyroid remains elusive. This systematic review aimed to gather primary evidence on the association between F and changes in the thyroid at optimal and high levels in water supply as stipulated by the World Health Organization...
2024: PloS One
#14
JOURNAL ARTICLE
Osayimwen Imade, Bobola V Ilesanmi, Germaine O Ogunwole, Olusola O Elekofehinti, Marília Cristina Oliveira Souza, Fernando Barbosa, Chris O Adedire, Joseph A Adeyemi
The toxic effects of 2, 4-dichlorophenol (2, 4-DCP) on aquatic organisms are well-established; however, the details regarding the mechanisms underlying the toxicity, especially immunotoxicity are poorly understood. Consequently, the aim of this study was to investigate the histopathologic, oxidative stress and immunotoxic effects attributed to exposure to sublethal concentrations of 2,4-DCP in the African catfish, Clarias gariepinus . Juvenile C. gariepinus were exposed to 0.4, 0.8, or 1.6 mg/L 2, 4-DCP for 28 days after which blood and head kidney were extracted for the determination of various nonspecific innate immune parameters while the liver was excised for histopathology examination and measurement of oxidative stress biomarkers...
April 9, 2024: Journal of Toxicology and Environmental Health. Part A
#15
JOURNAL ARTICLE
Bruna I Pilger, Alex Castro, Franciane F Vasconcellos, Karen F Moura, Étore De Favari Signini, Luis Felipe B Marqueze, Edson A Fiorenza-Neto, Mateus T Rocha, Giulia S Pedroso, Claudia R Cavaglieri, Antonio G Ferreira, Caique Figueiredo, Luciele G Minuzzi, Guilherme H Gatti da Silva, Gabriela S Castro, Fábio S Lira, Marilia Seelaender, Ricardo A Pinho
We investigated the effects of obesity on metabolic, inflammatory, and oxidative stress parameters in the adipose tissue of patients with fatal COVID-19. Postmortem biopsies of subcutaneous adipose tissue were obtained from 25 unvaccinated inpatients who passed from COVID-19, stratified as nonobese (N-OB; body mass index [BMI], 26.5 ± 2.3 kg m-2 ) or obese (OB BMI 34.2 ± 5.1 kg m-2 ). Univariate and multivariate analyses revealed that body composition was responsible for most of the variations detected in the metabolome, with greater dispersion observed in the OB group...
April 9, 2024: Journal of Cellular Biochemistry
#16
JOURNAL ARTICLE
Martin S Mullett, Anna R Harris, Bruno Scanu, Kris Van Poucke, Jared LeBoldus, Elizabeth Stamm, Tyler B Bourret, Petya K Christova, Jonás Oliva, Miguel A Redondo, Venche Talgø, Tamara Corcobado, Ivan Milenković, Marília Horta Jung, Joan Webber, Kurt Heungens, Thomas Jung
Phytophthora pseudosyringae is a self-fertile pathogen of woody plants, particularly associated with tree species from the genera Fagus, Notholithocarpus, Nothofagus and Quercus, which is found across Europe and in parts of North America and Chile. It can behave as a soil pathogen infecting roots and the stem collar region, as well as an aerial pathogen infecting leaves, twigs and stem barks, causing particular damage in the United Kingdom and western North America. The population structure, migration and potential outcrossing of a worldwide collection of isolates were investigated using genotyping-by-sequencing...
April 2024: Molecular Plant Pathology
#17
EDITORIAL
Marilia Barreca, Francesco Bertoni, Paola Barraja
No abstract text is available yet for this article.
March 20, 2024: European Journal of Medicinal Chemistry
#18
JOURNAL ARTICLE
Katja Weiss, David Valero, Elias Villiger, Mabliny Thuany, Pedro Forte, Robert Gajda, Volker Scheer, Sreten Sreckovic, Ivan Cuk, Pantelis T Nikolaidis, Marilia Santos Andrade, Beat Knechtle
The 50-km ultra-marathon is a popular race distance, slightly longer than the classic marathon distance. However, little is known about the country of affiliation and age of the fastest 50-km ultra-marathon runners and where the fastest races are typically held. Therefore, this study aimed to investigate a large dataset of race records for the 50-km distance race to identify the country of affiliation and the age of the fastest runners as well as the locations of the fastest races. A total of 1,398,845 50-km race records (men, n = 1,026,546; women, n = 372,299) were analyzed using both descriptive statistics and advanced regression techniques...
April 5, 2024: Scientific Reports
#19
JOURNAL ARTICLE
Vitor Fernandes Silva, Marília Tedesco, Silvia Terra Fontes, Marco Shizuo Owatari, Yuri Malaquias Gauglitz Gatto, Matheus Berlofa Ferreira, Paola Capistrano Dos Santos, Gabriel Antonio Cuzma Costa, Adriano Faria Palmieri, Gracienhe Gomes Dos Santos, Miguel Saldaña-Serrano, Afonso Celso Dias Bainy, Maurício Laterça Martins, José Luiz Pedreira Mouriño
Zinc is one of the essential microelements for the metabolism of animals. Zinc nanoparticles may have higher bioavailability due to their low specific surface area, facilitating absorption by fish. The present study aimed to evaluate the effects of supplementation with different zinc-based products on the growth and health of Nile tilapia Oreochromis niloticus. Zinc, in different sizes (nanoparticles or bulk) and forms (inorganic or organic), were used as a supplement in the tilapia diet at a dose of 15 mg kg feed-1 for 60 days...
April 2, 2024: Fish & Shellfish Immunology
#20
JOURNAL ARTICLE
Gabriela Salim de Castro, Leonardo R Gama, Alexandre Ferreira Ramos, Guilherme Gatti da Silva, Alexandre Abilio de Souza Teixeira, Edecio Cunha-Neto, Heraldo Possolo de Souza, Suely K Marie, Leda L Talib, Verônica Coelho, Jorge Kalil, Adriana Ladeira de Araujo, Ana Paula Ritto, Alessandro Rodrigo Belon, Amanda Soares Santos, Ana Paula Noronha Barrére, Márcio V Y Sawamura, Celina Almeida Lamas, Bruno Guedes Baldi, Carlos R R Carvalho, Leslie Domenici Kulikowski, Rodolfo Furlan Damiano, Marta Imamura, José Cesar Rosa Neto, Fabio S Lira, José Pinhata Otoch, Euripedes Constantino Miguel, Linamara Battistella, Orestes V Forlenza, Geraldo Busatto, Marilia Seelaender
INTRODUCTION: Post-COVID-19 condition (PCC) is characterised by a plethora of symptoms, with fatigue appearing as the most frequently reported. The alterations that drive both the persistent and post-acute disease newly acquired symptoms are not yet fully described. Given the lack of robust knowledge regarding the mechanisms of PCC we have examined the impact of inflammation in PCC, by evaluating serum cytokine profile and its potential involvement in inducing the different symptoms reported...
2024: Frontiers in Nutrition
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