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https://www.readbyqxmd.com/read/27910447/design-of-the-polar-neutron-imaging-aperture-for-use-at-the-national-ignition-facility
#1
V E Fatherley, D A Barker, D N Fittinghoff, R L Hibbard, J I Martinez, F E Merrill, J A Oertel, D W Schmidt, P L Volegov, C H Wilde
The installation of a neutron imaging diagnostic with a polar view at the National Ignition Facility (NIF) required design of a new aperture, an extended pinhole array (PHA). This PHA is different from the pinhole array for the existing equatorial system due to significant changes in the alignment and recording systems. The complex set of component requirements, as well as significant space constraints in its intended location, makes the design of this aperture challenging. In addition, lessons learned from development of prior apertures mandate careful aperture metrology prior to first use...
November 2016: Review of Scientific Instruments
https://www.readbyqxmd.com/read/27878858/non-invasive-tools-for-the-diagnosis-of-cutaneous-melanoma
#2
REVIEW
C Fink, H A Haenssle
BACKGROUND: While the excisional biopsy and histological examination of suspicious lesions remains the current gold standard for diagnosing cutaneous melanoma (CM), there is a demand for more objective and non-invasive examination methods that may support clinicians in their decision when to biopsy or not. METHODS: This review is based on publications and guidelines retrieved by a selective search in PubMed and MEDLINE and focused on non-invasive diagnostic strategies for detecting melanoma...
November 22, 2016: Skin Research and Technology
https://www.readbyqxmd.com/read/27867851/percutaneous-endoscopic-treatment-for-urinary-stones-in-pediatric-patients-where-we-are-now
#3
Paolo Caione, Giuseppe Collura, Michele Innocenzi, Mauro De Dominicis, Simona Gerocarni Nappo, Nicola Capozza
BACKGROUND: Percutaneous nephrolithotomy (PCNL) has been adopted for pyelo-calyceal stones treatment in pediatric patients, starting from the 90's. Very recently, miniaturization of endoscopic instruments allowed less invasive procedures with low complication rate. We reviewed our experience on upper tract stone treatment utilizing two different percutaneous accesses, focusing on the recent new miniaturized devices offered for pediatric renal stones. METHODS: Patients presenting upper tract urinary stones observed from January 2011 to December 2015 and treated by percutaneous renal access were prospectively evaluated: age, sex, metabolic issues, associated abnormalities, treatment modalities, hospital stay and complication rate were recorded in a specific database...
October 2016: Translational pediatrics
https://www.readbyqxmd.com/read/27834836/proteomic-analysis-of-tung-tree-vernicia-fordii-oilseeds-during-the-developmental-stages
#4
Zhiyong Zhan, Yicun Chen, Jay Shockey, Xiaojiao Han, Yangdong Wang
The tung tree (Vernicia fordii), a non-model woody plant belonging to the Euphorbiaceae family, is a promising economic plant due to the high content of a novel high-value oil in its seeds. Many metabolic pathways are active during seed development. Oil (triacylglycerols (TAGs)) accumulates in oil bodies distributed in the endosperm cells of tung tree seeds. The relationship between oil bodies and oil content during tung tree seed development was analyzed using ultrastructural observations, which confirmed that oil accumulation was correlated with the volumes and numbers of oil bodies in the endosperm cells during three different developmental stages...
November 8, 2016: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/27815023/comparative-analysis-of-the-serum-proteome-for-biomarker-discovery-to-reveal-hepatotoxicity-induced-by-iron-ion-radiation-in-mice
#5
Hongyan Li, Yuxuan He, Cuixia Di, Jiawei Yan, Hong Zhang
AIMS: Proteomic analysis of serum biomarkers to determine liver toxicity after exposure to cosmic radiation has not been performed previously. This study was to identify serum biomarkers associated with hepatotoxicity following exposure to iron ion radiation. MAIN METHODS: Male mice were whole-body irradiated with a 2grayunit (Gy) iron ion beam, and after 3months, serum and liver samples were collected. Two-dimensional electrophoresis was used to separate the identified serum proteins, and matrix-assisted laser desorption/ionization tandem mass spectrometry (MALDI-TOF-TOF) was performed to identify differentially abundant proteins...
November 1, 2016: Life Sciences
https://www.readbyqxmd.com/read/27789303/stone-attenuation-values-measured-by-average-hounsfield-units-and-stone-volume-as-predictors-of-total-laser-energy-required-during-ureteroscopic-lithotripsy-using-holmium-yttrium-aluminum-garnet-lasers
#6
Mitsuo Ofude, Takashi Shima, Satoshi Yotsuyanagi, Daisuke Ikeda
OBJECTIVE: To evaluate the predictors of the total laser energy (TLE) required during ureteroscopic lithotripsy (URS) using the holmium:yttrium-aluminum-garnet (Ho:YAG) laser for a single ureteral stone. MATERIALS AND METHODS: We retrospectively analyzed the data of 93 URS procedures performed for a single ureteral stone in our institution from November 2011 to September 2015. We evaluated the association between TLE and preoperative clinical data, such as age, sex, body mass index, and noncontrast computed tomographic findings, including stone laterality, location, maximum diameter, volume, stone attenuation values measured using average Hounsfield units (HUs), and presence of secondary signs (severe hydronephrosis, tissue rim sign, and perinephric stranding)...
October 24, 2016: Urology
https://www.readbyqxmd.com/read/27770310/treating-alopecia-areata-current-practices-versus-new-directions
#7
Aditya K Gupta, Jessie Carviel, William Abramovits
Alopecia areata (AA) is non-scarring hair loss resulting from an autoimmune disorder. Severity varies from patchy hair loss that often spontaneously resolves to severe and chronic cases that can progress to total loss of scalp and body hair. Many treatments are available; however, the efficacy of these treatments has not been confirmed, especially in severe cases, and relapse rates are high. First-line treatment often includes corticosteroids such as intralesional or topical steroids for mild cases and systemic steroids or topical immunotherapy with diphenylcyclopropenone or squaric acid dibutylester in severe cases...
October 22, 2016: American Journal of Clinical Dermatology
https://www.readbyqxmd.com/read/27743629/effect-of-posture-on-the-aerodynamic-characteristics-during-take-off-in-ski-jumping
#8
Keizo Yamamoto, Makoto Tsubokura, Jun Ikeda, Keiji Onishi, Sophie Baleriola
The purpose of this study was to investigate the effects of posture of a ski jumper on aerodynamic characteristics during the take-off using computational fluid dynamics (CFD). The CFD method adopted for this study was based on Large-Eddy Simulation. Body surface data were obtained by 3-D laser scanning of an active ski jumper. Based on video analysis of the actual take-off movement, two sets of motion data were generated (world-class jumper A and less-experienced jumper B). The inlet flow velocity that corresponds to the in-run velocity in actual ski jumping was set to 23...
October 6, 2016: Journal of Biomechanics
https://www.readbyqxmd.com/read/27736717/wear-resistance-and-compression-strength-of-ceramics-tested-in-fluoride-environments
#9
Guilherme Teixeira Theodoro, Lívia Fiorin, Izabela Cristina Maurício Moris, Renata Cristina Silveira Rodrigues, Ricardo Faria Ribeiro, Adriana Cláudia Lapria Faria
Dental ceramics have been widely used because of aesthetic, but wear is still questioned. There are relates that ceramic surface is prone to degradation by acidulated fluoride, that can increase wear rates. The aim of this study was to evaluate the effect of neutral and acidulated fluoride gel, used as preventive agents for professional use, at wear and compression strength of dental ceramics IPS e.max ZirPress (ZIR), IPS Empress Esthetic (EMP) e IPS Inline POM (POM). For this, 30 crowns and 30 disks were obtained by heat-pressing...
September 28, 2016: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/27706010/foreign-bodies-in-the-urinary-bladder-and-their-management-a-single-centre-experience-from-north-india
#10
Ankur Bansal, Priyank Yadav, Manoj Kumar, Satyanarayan Sankhwar, Bimalesh Purkait, Ankur Jhanwar, Siddharth Singh
PURPOSE: This study was performed to characterise the nature, clinical presentation, mode of insertion, and management of intravesical foreign bodies in patients treated at our hospital. METHODS: Between January 2008 and December 2014, 49 patients were treated for intravesical foreign bodies at King George Medical University, Lucknow. All records of these patients were retrospectively analysed to characterise the nature of the foreign body, each patient's clinical presentation, the mode of insertion, and how the case was managed...
September 2016: International Neurourology Journal
https://www.readbyqxmd.com/read/27688441/cutaneous-leishmaniasis-in-a-nonendemic-area-of-south-rajasthan-a-prospective-study
#11
Manisha Balai, Lalit Kumar Gupta, Ashok Kumar Khare, Ankita Srivastava, Asit Mittal, Ajit Singh
BACKGROUND: Cutaneous leishmaniasis (CL) usually occurs in areas with hot and dry climate. In India, the desert areas of Rajasthan, Gujarat, and the plains of Northwestern frontier are endemic for this disorder. AIMS AND OBJECTIVES: The present study was aimed to describe clinicoepidemiological profile of the cases of CL from South Rajasthan, which is a nonendemic area of Rajasthan. MATERIALS AND METHODS: During a period of 4 years (2010-2014), a total of 23 patients with CL were diagnosed...
September 2016: Indian Journal of Dermatology
https://www.readbyqxmd.com/read/27604964/holmium-yag-laser-ablation-for-the-management-of-lower-urinary-tract-foreign-bodies-following-incontinence-surgery-a-case-series-and-systematic-review
#12
Garson Chan, Adiel Mamut, Paul Martin, Blayne Welk
INTRODUCTION: The objective of this study was to determine the outcomes associated with the endoscopic removal of foreign bodies (such as mesh or permanent suture) in the lower urinary tract after female stress incontinence surgery with the Holmium:YAG (Ho:YAG) laser, and to systematically review the literature on this topic. MATERIALS AND METHODS: A retrospective chart review of 18 consecutive women found to have mesh or suture exposure was performed. All patients underwent Ho:YAG laser ablation...
October 6, 2016: Journal of Endourology
https://www.readbyqxmd.com/read/27604373/factors-affecting-complication-rates-of-retrograde-flexible-ureterorenoscopy-analysis-of-1571-procedures-a-single-center-experience
#13
Okan Baş, Can Tuygun, Onur Dede, Sercan Sarı, Mehmet Çağlar Çakıcı, Ufuk Öztürk, Göksel Göktuğ, Abdurrahim İmamoğlu
PURPOSE: To evaluate the factors affecting complication rates of flexible ureteroscopy and laser lithotripsy (FURSL). MATERIALS AND METHODS: Data on a total of 1395 patients, with 1411 renal units underwent 1571 procedures with FURSL for renal and/or proximal ureteral stones between April 2012 and January 2016, were retrospectively analyzed. Complications were assessed using the Satava and modified Clavien systems. Univariate and multivariate analyses were done to determine predictive factors affecting complication rates...
September 7, 2016: World Journal of Urology
https://www.readbyqxmd.com/read/27599662/antimicrobial-susceptibility-and-body-site-distribution-of-community-isolates-of-coagulase-negative-staphylococci
#14
Jorunn Pauline Cavanagh, Runa Wolden, Philipp Heise, Eirin Esaiassen, Claus Klingenberg, Elizabeth G Aarag Fredheim
The primary aim of this study was to determine antimicrobial resistance in coagulase-negative staphylococci (CoNS) from healthy adults in the community. Healthy adults (n = 114) were swabbed on six body sites; both armpits, both knee pits and both sides of the groin. Species determination was performed using Matrix Assisted Laser Desorption Ionization - Time of Flight (MALDI-TOF) and susceptibility testing for 11 relevant antimicrobials was performed by the disc diffusion method and minimal inhibitory concentration gradient test...
November 2016: APMIS: Acta Pathologica, Microbiologica, et Immunologica Scandinavica
https://www.readbyqxmd.com/read/27549157/external-comparison-of-recent-predictive-nomograms-for-stone-free-rate-using-retrograde-flexible-ureteroscopy-with-laser-lithotripsy
#15
Akif Erbin, Abdulkadir Tepeler, Ibrahim Buldu, Harun Ozdemir, Muhammed Tosun, Murat Binbay
OBJECTIVE: To assess and compare the applicability of the Resorlu-Unsal Stone Score (RUSS) and the Modified Seoul National University Renal Stone Complexity (S-ReSC) score for flexible ureterorenoscopy (f-URS). PATIENTS AND METHODS: We retrospectively analyzed the hospital files of 719 patients who had been treated with f-URS for kidney stone at two referral centers between July 2012 and December 2015. The RUSS and Modified S-ReSC scores were calculated by the same surgeon for each patient using imaging methods and were compared as to their predictive capability for postoperative success...
August 22, 2016: Journal of Endourology
https://www.readbyqxmd.com/read/27500574/-determination-of-the-rational-extent-of-laser-assisted-resection-for-the-treatment-of-paralytic-laryngeal-stenosis
#16
S A Karpishchenko, O I Dolgov
The objective of the present study was to improve the procedures for extended and restricted laser-assisted laryngoplasty in the patients presenting withparalytic laryngeal stenosis and to evaluate the outcome of the surgical interventionsdiffering in extent. The study included 51 patients (47 women and 4 men) at the age varying from 18 to 78 years. Twenty five of these patients had a tracheostoma. The examination was focused on the detection of the following characteristics: vocal fold angle, body mass index, age, specific anatomical and physiological features of the larynx, clinically significant concomitant pathologies, engagement in voice and speech professional activities as well as the influence of paramedical factors...
2016: Vestnik Otorinolaringologii
https://www.readbyqxmd.com/read/27473749/using-auriculotherapy-for-osteoarthritic-knee-among-elders-a-double-blinded-randomised-feasibility-study
#17
Lorna K P Suen, Chao Hsing Yeh, Simon K W Yeung
BACKGROUND: Osteoarthritic knee (OA knee) is a common condition in the elderly. Exploration of non-invasive complementary therapies for OA knee is warranted given the limitations of pharmacologic therapies. Auriculotherapy (AT) is a therapeutic method in which specific points on the auricle are stimulated to treat various disorders of the body, and the therapeutic value and synergistic effect of laser auriculotherapy (LAT) when combined with magneto-auriculotherapy (MAT) merits further investigation...
July 29, 2016: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/27464622/peripheral-blood-flow-changes-in-response-to-postexercise-cold-water-immersion
#18
Hui C Choo, Kazunori Nosaka, Jeremiah J Peiffer, Mohammed Ihsan, Chow C Yeo, Chris R Abbiss
This study compared the effect of postexercise water immersion (WI) at different temperatures on common femoral artery blood flow (CFA), muscle (total haemoglobin; tHb) and skin perfusion (cutaneous vascular conductance; CVC), assessed by Doppler ultrasound, near-infrared spectroscopy (NIRS) and laser Doppler flowmetry, respectively. Given that heat stress may influence the vascular response during cooling, nine men cycled for 25 min at the first ventilatory threshold followed by intermittent 30-s cycling at 90% peak power until exhaustion at 32·8 ± 0·4°C and 32 ± 5% RH...
July 28, 2016: Clinical Physiology and Functional Imaging
https://www.readbyqxmd.com/read/27402664/increase-of-cortical-cerebral-blood-flow-and-further-cerebral-microcirculatory-effects-of-serelaxin-in-a-sheep-model
#19
Sabine J Bischoff, Martin Schmidt, Thomas Lehmann, Andrey Irintchev, Harald Schubert, Christian Jung, Matthias Schwab, Otmar Huber, Georg Matziolis, René Schiffner
Serelaxin, recombinant human relaxin-2, modulates endothelial vasodilatory functionality and is under evaluation for treatment of acute heart failure. Little is known about acute effects on cerebral perfusion. We tested the hypothesis that Serelaxin might also have effects on the cerebral microcirculation in a sheep model, which resembles human brain structure quite well. We used laser Doppler flowmetry and sidestream dark-field (SDF) imaging techniques, which are reliable tools to continuously assess dynamic changes in cerebral perfusion...
September 1, 2016: American Journal of Physiology. Heart and Circulatory Physiology
https://www.readbyqxmd.com/read/27398914/comparison-of-three-timing-systems-reliability-and-best-practice-recommendations-in-timing-short-duration-sprints
#20
Colin W Bond, Emily M Willaert, Benjamin C Noonan
With the importance placed on athletic speed, it is important to utilize a valid and reliable timing system, particularly in sprints of short duration. Unfortunately, many of the commonly used timing systems have not been rigorously evaluated. This study aimed to compare results from a single-beam infrared photocell (PC), single-beam laser with a microprocessor (LA), and a previously validated video camera (VC) sacrum based timing system; and in doing so, determine these systems' reliabilities, and establish best practices for increasing reliability...
July 7, 2016: Journal of Strength and Conditioning Research
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