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Camila O de Souza, Gretchen K Vannice, José C Rosa Neto, Philip C Calder
Although dietary fatty acids can modulate metabolic and immune responses, the effects of palmitoleic acid (16:1n-7) remain unclear. Since this monounsaturated fatty acid is described as a lipokine, studies with cell culture and rodent models have suggested it enhances whole body insulin sensitivity, stimulates insulin secretion by β cells, increases hepatic fatty acid oxidation, improves the blood lipid profile, and alters macrophage differentiation. However, human studies report elevated blood levels of palmitoleic acid in people with obesity and metabolic syndrome...
January 2018: Molecular Nutrition & Food Research
Paulina Rolska, Jolanta Łapa
Breast cancer is one of the most common diseases in the Polish society. In 2015, around 17,000 Polish women were diagnosed with this type of cancer. A comparison of relative survival rates for different European countries shows that the Polish oncological care system is inefficient in terms of breast cancer treatment. Women in Poland have substantially lower chances of surviving the first five years a er being diagnosed than women in most other European countries. An inspiration, and at the same time the main theme of the paper is assessing the availability of a controversial treatment, i...
2016: Folia Medica Cracoviensia
Aleksandar Kupusinac, Edita Stokić, Enes Sukić, Olivera Rankov, Andrea Katić
Although body mass index (BMI) and body fat percentage (B F %) are well known as indicators of nutritional status, there are insuficient data whether the relationship between them is linear or not. There are appropriate linear and quadratic formulas that are available to predict B F % from age, gender and BMI. On the other hand, our previous research has shown that artificial neural network (ANN) is a more accurate method for that. The aim of this study is to analyze relationship between BMI and B F % by using ANN and big dataset (3058 persons)...
January 2017: Journal of Medical Systems
Jiangang Zhu, Mao Zhang
OBJECTIVE: To analyze the characteristics of severe trauma patients with acute kidney injury (AKI) receiving renal replacement therapy (RRT), in order to look for the risk factors of AKI and the opportune time for the initiation of RRT on prognosis. METHODS: A retrospective cohort study involving consecutive patients with severe trauma in emergency intensive care unit (ICU) in the Second Affiliated Hospital of Zhejiang University School of Medicine, from August 2011 to December 2014, was conducted...
May 2015: Zhonghua Wei Zhong Bing Ji Jiu Yi Xue
David González Jiménez, Carlos Bousoño García, Juan Jose Díaz Martin, Santiago Jiménez Treviño
INTRODUCTION AND OBJECTIVE: Evaluate the safety and efficacy of a novel polyvitaminic (Aquadek's®) in patients with Cystic Fibrosis (CF). MATERIAL AND METHODS: Prospective, longitudinal and non-randomized study. CF patients with pancreatic insufficiency and clinically stable were given Aquadek's® (two chewable tablets) daily for 12 months. Serum levels of retinol, beta-carotene, 25 OH vitamin D and α-tocopherol were evaluated twelve months before, at baseline and 12 months after...
April 1, 2015: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
Terri Y Lim, Robert L Poole, Natalie M Pageler
Propylene glycol (PG) is a commonly used solvent for oral, intravenous, and topical pharmaceutical agents. Although PG is generally considered safe, when used in high doses or for prolonged periods, PG toxicity can occur. Reported adverse effects from PG include central nervous system (CNS) toxicity, hyperosmolarity, hemolysis, cardiac arrhythmia, seizures, agitation, and lactic acidosis. Patients at risk for toxicity include infants, those with renal or hepatic insuficiency, epilepsy, and burn patients receiving extensive dermal applications of PG containing products...
October 2014: Journal of Pediatric Pharmacology and Therapeutics: JPPT: the Official Journal of PPAG
Isabel Graupera, Oana Pavel, Virginia Hernandez-Gea, Alba Ardevol, Susan Webb, Eulalia Urgell, Alan Colomo, Jordina Llaó, Mar Concepción, Càndid Villanueva
BACKGROUND & AIMS: Relative adrenal insufficiency (RAI) is common in critical illness and in cirrhosis, and is related with worse outcomes. The prevalence of RAI may be different in variceal and non-variceal bleeding and whether it may influence outcomes in these settings is unclear. This study assesses RAI and its prognostic implications in cirrhosis with variceal bleeding and in peptic ulcer bleeding. METHODS: Patients with severe bleeding (systolic pressure <100 mmHg and/or haemoglobin <8 g/L) from oesophageal varices or from a peptic ulcer were included...
August 2015: Liver International: Official Journal of the International Association for the Study of the Liver
Oana Deleanu, Ana Nebunoiu, Carolina Tarasova, Aneta Serbescu, Radu Stoica, Genoveva Cadar, Oana Arghir, Florin Mihaltan
SESSION TITLE: Interstitial Lung Disease Posters IISESSION TYPE: Original Investigation PosterPRESENTED ON: Wednesday, October 29, 2014 at 01:30 PM - 02:30 PMPURPOSE: We aimed to describe clinical features of a rare condition which determines an interstitial-like syndrome - pulmonar alveolar proteinosis (PAP), specific imagistic, pathologic findings and to describe our center's experience in whole lung lavage (WLL), main PAP treatment accepted at this moment.METHODS: We effectuated a retrospective analysis of all files from all admissions of patients with PAP from the period January 2007- December 2012 in a tertiar pneumology center in Romania; data where noted and analyzed...
October 1, 2014: Chest
Catarina Tavares, Amélia Maria Monteiro Fernandes Nunes, António João Santos Nunes, Maria Vaz Pato, Pedro Miguel Lourenço Monteiro
PURPOSE: Translate and adapt the Convergence Insuficiency Symptom Survey (CISS) questionnaire to the Portuguese language and culture and assess the psychometric properties of the translated questionnaire (CISSvp). METHODS: The CISS questionnaire was adapted according to the methodology recommended by some authors. The process involved two translations and back-translations performed by independent evaluators, evaluation of these versions, preparation of a synthesis version and its pre-test...
January 2014: Arquivos Brasileiros de Oftalmologia
Sava V Perovic, Rados P Djinovic
OBJECTIVES: To report the principles of penile resculpturing of different deformities caused by M. Peyronie: restoration of penile length, girth and shape with or without penile prosthesis implantation. METHODS: In the period between February 2007 and March 2009, we performed grafting surgery for M. Peyronie in 98 patients aged between 24 and 72 years (mean 52 years). Penile deformities were diferent: dorsal curvature in 54 (55%), lateral in 7 (7%), ventral in 11 (11%), and combined curvature in 21 (21%) associated corporal narrowing was present in 24 patients (24%)...
November 2010: Archivos Españoles de Urología
A Podskubka, M Stasa, V Dvorák, J Vaculík
Arthroscopic subacromial decompression is a generally recognized method of the treatment of the primary impingement sydrome and is one of the basic arthroscopic methods. The data in literature present 73-94 % of good and very good results. From May 1993 till June 1996 we treated at our clinic 40 patients with arthroscopic subacromial decompression of which 38 patients were followed up. The average period of follow-up is 3 years (2-5 years). All patients had clinical symptoms of impingement syndrome prior to operation...
2000: Acta Chirurgiae Orthopaedicae et Traumatologiae Cechoslovaca
Pablo Maria Alberto Pomerantzeff, Carlos Manuel de Almeida Brandão, Osanan Amorim Leite Filho, Marco Antônio Vieira Guedes, Marcos Floripes da Silva, Max Grinberg, Noedir Antônio Groppo Stolf
OBJECTIVE: Mitral valve repair in rheumatic patients is still a challenge. The purpose of this study is to analyze the results of mitral valve repair in rheumatic patients in the Heart Institute University of Sao Paulo Medical School. METHODS: Were analyzed retrospectively, between 1985 and 2005, 330 patients submitted to mitral valve repair in the Heart Institute of São Paulo. The mean age was 26.9 +/- 15.4 years and 57.6% were female. According do clinical evaluation, 39...
October 2009: Revista Brasileira de Cirurgia Cardiovascular
V Shvarts
Pharmaceutical products reviewed in this paper markedly extend possibilities for the management of DM-2 and create prerequisites for diferential therapy of this disease. Exenatide and DPP-4 inhibitors do not cause hypoglycemia and may be prescribed to subjects in whom this condition may affect the ability to drive or operate machinery (drivers, pilots, etc.). The mechanism of action of DPP-4 inhibitors make them especially suitable for the treatment of early stages of DM-2 when B-cells are still capable of insulin secretion...
2008: Klinicheskaia Meditsina
Tadeusz Przewłocki, Anna Kabłak-Ziembicka, Wiesława Tracz, Artur Kozanecki, Grzegorz Kopeć, Paweł Rubiś, Magdalena Kostkiewicz, Agnieszka Rosławiecka, Daniel Rzeźnik, Tomasz Stompór
BACKGROUND: Renal dysfunction is an important factor of cardiovascular risk. Renal artery stenosis (RAS) is a potential cause of secondary hypertension and by renal ischemia may lead to progressive renal insuficiency. In RAS patients a significant increase in prevalence of coronary artery disease (CAD) as well as revascularisation rate and mortality rate was observed. AIM: To determine the prevalence of RAS in patients with suspected CAD. METHODS: The study group consisted of 1036 consecutive patients (700 men; 67...
August 2008: Kardiologia Polska
Tea Carić, Ozren Derek, Drago Carić
Erythropoietin (EPO), traditionally known as a hematopoietic hormone, has recently been shown to have effects beyond hematopoiesis such as prevention of neuronal and cardiac apoptosis secondary to ischemia and induction of neoangiogenesis. Patients with congestive heart failure (CHF) suffer considerable morbidity and mortality despite advances in therapy. Anemia, CHF, and chronic kidney insuficiency often coexist and interact to cause or worsen each other in the so-called cardio-renal anemia syndrome. Treatment with EPO has shown promise in such patients...
June 2008: Collegium Antropologicum
K Smejkal, T Dĕdek, I Zvák, J Trlica, J Folvarský, I Pocepcov, J Zahradnícek, T Holecek, J Kocí, M Frank
BACKGROUND: Fractures of the proximal humerus actually represent 5% of all fractures and 45% of all humeral fractures with the highest incidence in women over 60 years of age. The outcomes of the greatest concern at these patients (pain, function of the shoulder and activities of daily living) get worse with age, osteoporosis, grading of fracture type and of initial fracture displacement. According to the literature (Evidence Based Medicine--EBM level II-III) operative treatment of displaced fractures reduces pain and need for assistance in activities of daily living, but open reduction with internal fixation by conventional screws and plates was connected with implant loosening, infection and avascular necrosis, whereas closed reduction with different methods of miniinvasive percutaneous stabilisation is threatened by primary malreduction...
February 2008: Rozhledy V Chirurgii: Měsíčník Československé Chirurgické Společnosti
Predrag Aleksić, Vladimir Bancević, Borislav Stijelja, Novak Milović, Perica Tosevski, Zoran Campara, Branko Kosević, Dejan Mocović
BACKGROUND/AIM: Today, radical cystectomy is the method of choice in treatment of muscle invasive bladder carcinoma in stage T2-T4a, No-Nx, Mo, and orthotopic derivation is for patients the most comfortable derivation of urin. From 1888 when Tizzoni and Foggi performed the first orthotopic derivation on animals, and 1913 when Lemoin declared the first orthotopic derivation in humans there has been a constant improvement and modification of orthotopic urinary diversion after radical cystectomy which significantly decrease the number and severity of postoperative complications...
February 2008: Vojnosanitetski Pregled. Military-medical and Pharmaceutical Review
V Barrio, C Quereda, J Zamora, F García López
OBJECTIVE: To estimate whether continuous veno-venous hemodiafiltration (CVVHDF) is superior to intermittent hemodialysis (IHD) in terms of survival of adult patients with acute renal failure (ARF) admitted to the Intensive Care Unit. SELECTION OF STUDIES: Controlled clinical trials (CCT) and systematic reviews comparing CWHDF and IHD for managing ARF in adult patients (age > 19 years). Observational and case series were excluded. SEARCH SOURCES: The basic syntax <hemodiafiltration OR continuous hemodi* OR continuous dialysis) and acute renal failure and acute renal insuficiency> was used to search Pub Med and Ovid System databases...
2007: Nefrología: Publicación Oficial de la Sociedad Española Nefrologia
P Valdivielso, J López-Sánchez, A Garrido, J J Sánchez-Carrillo
Primary hyperparathyroidism is rarely produced by parathyroid carcinoma. We present the case of a 63-yr-old man who was admitted due to recent onset of constipation, weakness and progressive lethargy. At physical examination, a left cervical mass was palpated. Marked hypercalcemia (serum calcium 25 mg/dl) (6.22 mmol/l) complicated by renal insuficiency (serum creatinine 4.4 mg/dl) (388 micromol/l) was found, but both were unresponsive to conventional therapy and hemofiltration. Autopsy examination showed a carcinoma of the upper left parathyroid gland, multiple foci of metastatic calficications in the vessel walls and parenchyma of both lungs and kidneys, and the myocardium, which contributed to multi-organ failure and death...
July 2006: Journal of Endocrinological Investigation
T Frangov, V Dimitrova
UNLABELLED: Cholangiocellular carcinoma is the second on rate primary liver cancer (7-10%), after hepatocellular carcinoma--(80-85%). The aim of this study is to present some diferrencies in clinical and pathological features in comparison to other liver tumors. MATERIALS AND METHODS: In the period 1991-2002 years, 105 patients with primary liver cancer were operated; 9 of them (8.5%) had cholangiocellular carcinoma (CCC). The men were 5, the women--4, and the mean age 51 years...
2004: Khirurgiia
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