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Amjid Ahad, Ajaz Ahmad Ganai, Mohd Mujeeb, Waseem Ahmad Siddiqui
Diabetic nepropathy (DN) is considered as the leading cause of end-stage renal disease (ESRD) worldwide, but the current available treatments are limited. Recent experimental evidences support the role of chronic microinflammation in the development of DN. Therefore, the tumor necrosis factor-alpha (TNF-α) pathway has emerged as a new therapeutic target for the treatment of DN. We investigated the nephroprotective effects of chrysin (5, 7-dihydroxyflavone) in a high fat diet/streptozotocin (HFD/STZ)-induced type 2 diabetic Wistar albino rat model...
August 15, 2014: Toxicology and Applied Pharmacology
P Cavallo-Perin, P Bodoni, S Marena
The main approach in NIDDM therapy is diet. Most patients present insulin resistance characterized by overweight, VLDL increase, minimal increase of LDL, decrease of HDL cholesterol, and hypertension. The overall goals of nutrition therapy are the maintenance of near normal glucose levels, and the achievement of optimal serum lipid levels with adequate calories for maintaining or attaining a reasonable body weight. In presence of obesity and hypertension even a slightly weight loss could achieve an improvement in metabolic control and in hypertension with a better life expectance...
December 1997: Minerva Gastroenterologica e Dietologica
W Arkouche, G Brillet, T Cao-Huu, B Issad, P Siohan, M Souid, P Stroumza, F Tollis, P Urena, J Pengloan
No abstract text is available yet for this article.
2004: Néphrologie
Peter Aspelin
No abstract text is available yet for this article.
June 5, 2003: Läkartidningen
R Burgos Calderón
The incidence of diabetes mellitus has increased dramatically in Puerto Rico. On 1996, it accounted for 56.8% of all new cases admitted for dialysis. By 1998 the number increased to 59.9%, of which, 88.5% were Type 2 diabetic patients. Strategies for the reduction or prevention of renal insufficiency of Type 2 diabetic patients should include: identification of potential chronic complications, review of risk factors related to diabetic nepropathy, and the evaluation of the arterial blood pressure and renal function...
June 2001: Puerto Rico Health Sciences Journal
J Reiterová, V Tesar, M Merta
Many controversial studies concerning relation between angiotensin converting enzyme polymorphism and renal and cardiovascular disease have been published during the last years. Most of the papers have suggested that the DD genotype plays an important negative role in the progression of some renal diseases (e.g. IgA nephropathy, diabetic nepropathy). The D allele may be an independent risk factor for development of the target organ damage in essential hypertension. The therapeutic response on inhibitors of angiotensin converting enzyme depends on insertion-deletion polymorphism...
May 2001: Casopís Lékar̆ů C̆eských
L J Petersen, S D Ladefoged, H A Jensen
This article describes the influence of antihypertensive treatment on the kidneys, both the acute and the long-term effects, especially with regard to the progression of chronic non-diabetic renal failure. Our knowledge about the different antihypertensive drugs is still limited, but some studies indicate that especially ACE-inhibition and perhaps calcium antagonism may have the potential to postpone renal failure.
July 28, 1997: Ugeskrift for Laeger
M E Miranda
No abstract text is available yet for this article.
1994: Advances in Experimental Medicine and Biology
K Hochstrasser, H Feuth, J Fall, B Kemkes
No abstract text is available yet for this article.
November 1, 1974: Klinische Wochenschrift
G Monga, G Mazzucco, R Castello
Glomerular monocyte infiltration was evaluated by histochemical means (nonspecific esterase) and/or electron microscopy in 305 renal biopsies belonging to a wide variety of human renal diseases. Significant monocyte infiltration was never observed in a first group of nepropathies (minimal change disease, nephrotic syndrome with IgM deposits, focal segmental glomerulosclerosis, membranous GN, Berger's GN, healed GN, dense deposit disease, chronic non specific GN, benign familial haematuria, Alport's disease, renal amyloidosis, arteriosclerotic kidney, light chain GN)...
1985: Virchows Archiv. A, Pathological Anatomy and Histopathology
R Sabra
A corticopapillary scar is a frequent finding on urography in patients with vesicoureteral reflux. It is considered a typical sign of so-called reflux nepropathy. It develops most frequently in children aged 5-7 years and has a negative impact on the growth of the kidney. In its development three factors participate: ureterovesical reflux, intrarenal reflux associated with so-called refluxing papillas and urinary infection. The inflammatory cicatrical process may affect the whole kidney--small shrivelled kidney--or only a portion of the kidney...
August 1990: Vnitr̆ní Lékar̆ství
B Gunev, B Nalbanski, R Raĭcheva, L Mitev, T Todorov
No abstract text is available yet for this article.
1979: Akusherstvo i Ginekologii︠a︡
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