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urinary catheter asymptomatic bacteriuria

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https://www.readbyqxmd.com/read/27780014/clinical-presentations-and-epidemiology-of-urinary-tract-infections
#1
Suzanne E Geerlings
Urinary tract infection (UTI) is one of the most common bacterial infections, and the incidence in women is much higher than in men. The diagnosis of a UTI can be made based on a combination of symptoms and a positive urine analysis or culture. Most UTIs are uncomplicated UTIs, defined as cystitis in a woman who is not pregnant, is not immunocompromised, has no anatomical and functional abnormalities of the urogenital tract, and does not exhibit signs of tissue invasion and systemic infection. All UTIs that are not uncomplicated are considered to be complicated UTIs...
October 2016: Microbiology Spectrum
https://www.readbyqxmd.com/read/27697086/infection-prevention-and-antimicrobial-stewardship-knowledge-for-selected-infections-among-nursing-home-personnel
#2
Barbara W Trautner, M Todd Greene, Sarah L Krein, Heidi L Wald, Sanjay Saint, Andrew J Rolle, Sara McNamara, Barbara S Edson, Lona Mody
OBJECTIVE To assess knowledge about infection prevention among nursing home personnel and identify gaps potentially addressable through a quality improvement collaborative. DESIGN Baseline knowledge assessment of catheter-associated urinary tract infection, asymptomatic bacteriuria, antimicrobial stewardship, and general infection prevention practices for healthcare-associated infections. SETTING Nursing homes across 14 states participating in the national "Agency for Healthcare Research and Quality Safety Program for Long-Term Care: Healthcare-Associated Infections/Catheter-Associated Urinary Tract Infection...
October 4, 2016: Infection Control and Hospital Epidemiology
https://www.readbyqxmd.com/read/27394021/urinary-tract-infections-in-the-older-adult
#3
REVIEW
Lindsay E Nicolle
Urinary infection is the most common bacterial infection in elderly populations. The high prevalence of asymptomatic bacteriuria in both men and women is benign and should not be treated. A diagnosis of symptomatic infection for elderly residents of long-term care facilities without catheters requires localizing genitourinary findings. Symptomatic urinary infection is overdiagnosed in elderly bacteriuric persons with nonlocalizing clinical presentations, with substantial inappropriate antimicrobial use. Residents with chronic indwelling catheters experience increased morbidity from urinary tract infection...
August 2016: Clinics in Geriatric Medicine
https://www.readbyqxmd.com/read/27391962/bacteraemia-during-transurethral-resection-of-the-prostate-what-are-the-risk-factors-and-is-it-more-common-than-we-think
#4
Amar Raj Mohee, Deborah Gascoyne-Binzi, Robert West, Selina Bhattarai, Ian Eardley, Jonathan A T Sandoe
The aim of this work was to investigate the microbial causes, incidence, duration, risk factors and clinical implications of bacteraemia occurring during transurethral resection of the prostate (TURP) surgery to better inform prophylaxis strategies. An ethically approved, prospective, cohort study of patients undergoing TURP was conducted. Clinical information and follow-up details were collected using standardized data collection sheets. Blood was obtained for culture at 6 different time points peri-procedure...
2016: PloS One
https://www.readbyqxmd.com/read/27334497/preliminary-study-on-serum-paraoxonase-1-status-and-chemokine-c-c-motif-ligand-2-in-hospitalized-elderly-patients-with-catheter-associated-asymptomatic-bacteriuria
#5
S Iftimie, A García-Heredia, I Pujol, F Ballester, I Fort-Gallifa, J M Simó, J Joven, J Camps, A Castro
Urinary tract infections (UTI) are common among elderly patients in residential care facilities, as well as in the hospital setting. Identifying new biochemical markers of UTI is an active line of research since UTI management is resource intensive. Paraoxonase-1 (PON1) forms part of the patient's immune system, the response-to-injury and inflammation. Our study sought to evaluate alterations in inflammation-related paraoxonase-1 (PON1) and chemokine (C-C motif) ligand 2 (CCL2) in patients with an indwelling catheter to assess their potential usefulness as biomarkers of infection...
September 2016: European Journal of Clinical Microbiology & Infectious Diseases
https://www.readbyqxmd.com/read/27263795/evaluating-a-hospitalist-based-intervention-to-decrease-unnecessary-antimicrobial-use-in-patients-with-asymptomatic-bacteriuria
#6
Sarah E Hartley, Latoya Kuhn, Staci Valley, Laraine L Washer, Tejal Gandhi, Jennifer Meddings, Michelle Robida, Salas Sabnis, Carol Chenoweth, Anurag N Malani, Sanjay Saint, Scott A Flanders
OBJECTIVE Inappropriate treatment of asymptomatic bacteriuria (ASB) in the hospital setting is common. We sought to evaluate the treatment rate of ASB at the 3 hospitals and assess the impact of a hospitalist-focused improvement intervention. DESIGN Prospective, interventional trial. SETTING Two community hospitals and a tertiary-care academic center. PATIENTS Adult patients with a positive urine culture admitted to hospitalist services were included in this study. Exclusions included pregnancy, intensive care unit admission, history of a major urinary procedure, and actively being treated for a urinary tract infection (UTI) at the time of admission or >48 hours prior to urine collection...
September 2016: Infection Control and Hospital Epidemiology
https://www.readbyqxmd.com/read/27104571/the-paradigm-shift-to-non-treatment-of-asymptomatic-bacteriuria
#7
Lindsay E Nicolle
Asymptomatic bacteriuria, also called asymptomatic urinary infection, is a common finding in healthy women, and in women and men with abnormalities of the genitourinary tract. The characterization and introduction of the quantitative urine culture in the 1950s first allowed the reliable recognition of asymptomatic bacteriuria. The observations that a substantial proportion of patients with chronic pyelonephritis at autopsy had no history of symptomatic urinary infection, and the high frequency of pyelonephritis observed in pregnant women with untreated asymptomatic bacteriuria, supported a conclusion that asymptomatic bacteriuria was harmful...
2016: Pathogens
https://www.readbyqxmd.com/read/27039283/distinguishing-asymptomatic-bacteriuria-from-urinary-tract-infection-in-the-elderly-the-use-of-urine-levels-of-heparin-binding-protein-and-interleukin-6
#8
Charlott Kjölvmark, Emilia Tschernij, Jonas Öberg, Lisa I Påhlman, Adam Linder, Per Åkesson
Asymptomatic bacteriuria (ABU) is highly prevalent among elderly patients. It can be difficult to distinguish ABU from symptomatic urinary tract infection (UTI) in this population, which leads to unnecessary antibiotic treatment. Urinary heparin-binding protein (U-HBP) and urinary interleukin-6 (U-IL-6) have previously been studied as diagnostic markers for UTI. In this study, biomarkers were measured in the urine of 134 nursing home residents. The prevalence of ABU in this population, excluding patients with urinary catheter, was 32...
June 2016: Diagnostic Microbiology and Infectious Disease
https://www.readbyqxmd.com/read/26953145/resistance-and-virulence-potential-of-uropathogenic-escherichia-coli-strains-isolated-from-patients-hospitalized-in-urology-departments-a-french-prospective-multicentre-study
#9
Jean-Philippe Lavigne, Franck Bruyère, Louis Bernard, Christophe Combescure, Esthel Ronco, Philippe Lanotte, Patrick Coloby, Michel Thibault, Gérard Cariou, Nicole Desplaces, Pierre Costa, Albert Sotto
We characterized antibiotic resistance and virulence of uropathogenic Escherichia coli (UPEC) strains isolated from urinary tract infections (UTIs) in patients hospitalized in urology departments. A prospective multicentre study was initiated from March 2009 and lasted until February 2010 in French urology units. All patients with asymptomatic bacteriuria (ABU), acute cystitis, acute pyelonephritis or acute prostatitis in whom UPEC was detected were included. Antimicrobial resistance and virulence factors were compared among the different groups...
June 2016: Journal of Medical Microbiology
https://www.readbyqxmd.com/read/26908118/-urinary-tract-infections-in-the-elderly
#10
N Mirsaidov, F M E Wagenlehner
Urinary tract infections (UTIs) and asymptomatic bacteriuria are frequent in elderly patients. Distinguishing UTI from asymptomatic bacteriuria in older adults, particularly those living in long-term care facilities, might be a challenge for physicians due to the presence of confounding factors, such as an overactive bladder, prostate enlargement, and an indwelling bladder catheter. The absence of standards in the definition and treatment of UTI in the elderly frequently leads to overtreatment. Consequently, antibiotic selection pressure increases and as a result multidrug-resistant organisms might arise...
April 2016: Der Urologe. Ausg. A
https://www.readbyqxmd.com/read/26904414/urinary-tract-infection-in-the-neurogenic-bladder
#11
REVIEW
Humberto R Vigil, Duane R Hickling
There is a high incidence of urinary tract infection (UTI) in patients with neurogenic lower urinary tract function. This results in significant morbidity and health care utilization. Multiple well-established risk factors unique to a neurogenic bladder (NB) exist while others require ongoing investigation. It is important for care providers to have a good understanding of the different structural, physiological, immunological and catheter-related risk factors so that they may be modified when possible. Diagnosis remains complicated...
February 2016: Translational Andrology and Urology
https://www.readbyqxmd.com/read/26661940/urethral-indwelling-or-intermittent-or-suprapubic-routes-for-short-term-catheterisation-in-hospitalised-adults
#12
REVIEW
Emily A Kidd, Fiona Stewart, Nadine C Kassis, Emily Hom, Muhammad Imran Omar
BACKGROUND: Indwelling urethral catheters are often used for bladder drainage in hospital. Urinary tract infection is the most common hospital-acquired infection, and a common complication of urinary catheterisation. Pain, ease of use and quality of life are important to consider, as well as formal economic analysis. Suprapubic catheterisation can also result in bowel perforation and death. OBJECTIVES: To determine the advantages and disadvantages of alternative routes of short-term bladder catheterisation in adults in terms of infection, adverse events, replacement, duration of use, participant satisfaction and cost effectiveness...
2015: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/26524804/asymptomatic-bacteriuria-screened-by-catheterized-samples-at-pregnancy-term-in-women-undergoing-cesarean-delivery
#13
T Atacag, E Yayci, T Guler, K Suer, F Yayci, S Deren, A Cetin
OBJECTIVE: The objective of this study was to assess the frequency of urinary tract infection (UTI) with urine samples obtained via catheterization among women undergoing cesarean delivery at term pregnancy. MATERIALS AND METHODS: A cross-sectional study involving 159 women in whom cesarean delivery was conducted at term pregnancy after a regular follow-up from first to third trimester. For screening and diagnosis of UTI during antenatal period, the authors used dipstick test and microscopic urinalysis, and urine culture was used in the presence of symptomatic UTI unresponsive to initial antibiotic therapy...
2015: Clinical and Experimental Obstetrics & Gynecology
https://www.readbyqxmd.com/read/26238715/similar-neutrophil-driven-inflammatory-and-antibacterial-responses-in-elderly-patients-with-symptomatic-and-asymptomatic-bacteriuria
#14
Yanbao Yu, Martin D Zielinski, Melanie A Rolfe, Melissa M Kuntz, Heidi Nelson, Karen E Nelson, Rembert Pieper
Differential diagnosis of asymptomatic bacteriuria (ASB) and urinary tract infection (UTI) is based on the presence of diverse symptoms, including fever (≥38.5°C), rigors, malaise, lethargy, flank pain, hematuria, suprapubic discomfort, dysuria, and urgent or frequent urination. There is consensus in the medical community that ASB warrants antibiotic treatment only for patients undergoing urological procedures that lead to mucosal bleeding, catheterized individuals whose ASB persists for more than 48 h after catheter removal, and pregnant women...
October 2015: Infection and Immunity
https://www.readbyqxmd.com/read/26010222/effectiveness-of-an-antimicrobial-stewardship-approach-for-urinary-catheter-associated-asymptomatic-bacteriuria
#15
Barbara W Trautner, Larissa Grigoryan, Nancy J Petersen, Sylvia Hysong, Jose Cadena, Jan E Patterson, Aanand D Naik
IMPORTANCE: Overtreatment of asymptomatic bacteriuria (ASB) in patients with urinary catheters remains high. Health care professionals have difficulty differentiating cases of ASB from catheter-associated urinary tract infections. OBJECTIVES: To evaluate the effectiveness and sustainability of an intervention to reduce urine culture ordering and antimicrobial prescribing for catheter-associated ASB compared with standard quality improvement methods. DESIGN, SETTING, AND PARTICIPANTS: A preintervention and postintervention comparison with a contemporaneous control group from July 2010 to June 2013 at 2 Veterans Affairs health care systems...
July 2015: JAMA Internal Medicine
https://www.readbyqxmd.com/read/25889401/diagnosing-inflammation-and-infection-in-the-urinary-system-via-proteomics
#16
Yanbao Yu, Patricia Sikorski, Cynthia Bowman-Gholston, Nicolas Cacciabeve, Karen E Nelson, Rembert Pieper
BACKGROUND: Current methodology for the diagnosis of diseases in the urinary system includes patient symptomology, urine analysis and urine culture. Asymptomatic bacteriuria from urethral colonization or indwelling catheters, sample contamination from perineal or vaginal sources, and non-infectious inflammatory conditions can mimic UTIs, leading to uncertainty on medical treatment decisions. METHODS: Innovative shotgun metaproteomic methods were used to analyze urine sediments from 120 patients also subjected to conventional urinalysis for various clinical reasons including suspected UTIs...
2015: Journal of Translational Medicine
https://www.readbyqxmd.com/read/25786842/-urinary-tract-infection-in-elderly-residents-of-long-term-care-facilities
#17
Mette Stærkind, Michael Dalager-Pedersen, Henrik Nielsen
Urinary tract infection is the most prevalent bacterial infection among residents in Danish long-term care facilities, and it is the most common reason for antibiotic therapy as prevention or treatment in this population. Diagnosis and management of urinary tract infection in the elderly is challenging because of benign asymptomatic bacteriuria, chronic indwelling urinary tract catheters, cognitive impairment and other co-morbidities. This review covers updated information on diagnosis, treatment and prophylaxis of urinary tract infection in elderly residents of long-term care facilities...
March 16, 2015: Ugeskrift for Laeger
https://www.readbyqxmd.com/read/25728152/safety-and-efficacy-of-a-novel-silver-impregnated-urinary-catheter-system-for-preventing-catheter-associated-bacteriuria-a-pilot-randomized-clinical-trial
#18
RANDOMIZED CONTROLLED TRIAL
Anne-Marie Leuck, James R Johnson, Matthew A Hunt, Kush Dhody, Kazem Kazempour, Patricia Ferrieri, Susan Kline
BACKGROUND: The purpose of this study was to evaluate the safety of a novel silver-impregnated Foley catheter system designed to prevent catheter-associated bacteriuria and funguria, assess recruitment feasibility for a future pivotal trial, and preliminarily assess efficacy. METHODS: This single-center, randomized controlled trial at a university hospital involved adult neurosurgical patients expected to have a urinary catheter for ≥24 hours. Subjects were randomized to a novel silver-impregnated (test) Foley catheter system or a control system...
March 1, 2015: American Journal of Infection Control
https://www.readbyqxmd.com/read/25673765/a-metaproteomics-approach-to-elucidate-host-and-pathogen-protein-expression-during-catheter-associated-urinary-tract-infections-cautis
#19
Christian Lassek, Melanie Burghartz, Diego Chaves-Moreno, Andreas Otto, Christian Hentschker, Stephan Fuchs, Jörg Bernhardt, Ruy Jauregui, Rüdiger Neubauer, Dörte Becher, Dietmar H Pieper, Martina Jahn, Dieter Jahn, Katharina Riedel
Long-term catheterization inevitably leads to a catheter-associated bacteriuria caused by multispecies bacterial biofilms growing on and in the catheters. The overall goal of the presented study was (1) to unravel bacterial community structure and function of such a uropathogenic biofilm and (2) to elucidate the interplay between bacterial virulence and the human immune system within the urine. To this end, a metaproteomics approach combined with in vitro proteomics analyses was employed to investigate both, the pro- and eukaryotic protein inventory...
April 2015: Molecular & Cellular Proteomics: MCP
https://www.readbyqxmd.com/read/25451882/nosocomial-urinary-tract-infections-a-review
#20
Valerio Iacovelli, Gabriele Gaziev, Luca Topazio, Pierluigi Bove, Giuseppe Vespasiani, Enrico Finazzi Agrò
Nosocomial urinary tract infections are a common complication in healthcare systems worldwide. A review of the literature was performed in June 2014 using the Medical Literature Analysis and Retrieval System Online (MEDLINE) database, through either PubMed or Ovid as a search engine, to identify publications regarding nosocomial urinary tract infections (NUTIs) definition, epidemiology, etiology and treatment.According to current definitions, more than 30% of nosocomial infections are urinary tract infections (UTIs)...
October 2014: Urologia
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