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ACS prognosis

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https://www.readbyqxmd.com/read/29313559/the-long-term-prognosis-following-acute-coronary-syndromes-a-prospective-observational-study-of-unselected-group-treated-in-the-24-7-cardiac-catheterization-laboratory-at-university-hospital
#1
Marcin Grabowski, Krzysztof J Filipiak, Grzegorz Opolski, Renata Główczyńska, Monika Gawałko, Paweł Balsam, Andrzej Cacko, Zenon Huczek, Grzegorz Karpiński, Robert Kowalik, Franciszek Majstrak, Janusz Kochman
BACKGROUND: The risk stratification in acute coronary syndrome (ACS) is usually based on the clinical data obtained during hospitalization. To date, there is a limited number of prospective observational studies assessing long-term prognosis of patients discharged from the hospital after ACS. AIM: This study is to investigate long-term follow-up of unselected ACS patients treated at the 24 hours/7 days (24/7) cardiac catheterization laboratory and discharged from referral, university hospital...
January 9, 2018: Kardiologia Polska
https://www.readbyqxmd.com/read/29297191/angiographic-advancement-of-the-coronary-disease-and-the-cardiovascular-risk-at-the-acute-coronary-syndrome-in-patients-with-the-metabolic-syndrome
#2
Katarzyna Widecka-Ostrowska, Krzysztof Safranow, Maciej Lewandowski, Krzysztof Przybycień, Jarosław Gorący, Zdzisława Kornacewicz-Jach
BACKGROUND: Extent of angiographic lesions, size of infarct and in-hospital and distant prognosis in patients with the metabolic syndrome have been not clearly determined. Detailed knowledge of markers both for ACS occurrence as well as those affecting early and further prognosis will have key significance at taking correct preventive and therapeutic decisions. AIM: Comparing in patients with first ACS treated with coronary angioplasty the advancement of coronary disease and the cardiovascular risk evaluated using GRACE 2...
January 3, 2018: Kardiologia Polska
https://www.readbyqxmd.com/read/29288404/paradoxical-impact-of-decreased-low-density-lipoprotein-cholesterol-level-at-baseline-on-the-long-term-prognosis-in-patients-with-acute-coronary-syndrome
#3
Takuya Nakahashi, Hayato Tada, Kenji Sakata, Yohei Yakuta, Yoshihiro Tanaka, Akihiro Nomura, Tadatsugu Gamou, Hidenobu Terai, Yuki Horita, Masatoshi Ikeda, Masanobu Namura, Masayuki Takamura, Kenshi Hayashi, Masakazu Yamagishi, Masa-Aki Kawashiri
Although statin therapy is beneficial in the setting of acute coronary syndrome (ACS), a substantial proportion of patients with ACS still do not receive the guideline-recommended lipid management in contemporary practice. We hypothesize that the low-density lipoprotein cholesterol (LDL-C) level at the time of admission might affect patient management and the subsequent outcome. Nine-hundred and forty-two consecutive patients with ACS who underwent percutaneous coronary intervention were analyzed retrospectively...
December 29, 2017: Heart and Vessels
https://www.readbyqxmd.com/read/29276176/coronary-aneurysms-in-the-acute-patient-incidence-characterization-and-long-term-management-results
#4
Iván J Núñez-Gil, Belén Terol, Gisela Feltes, Luis Nombela-Franco, Pablo Salinas, Javier Escaned, Pilar Jiménez-Quevedo, Nieves Gonzalo, David Vivas, Daniel Bautista, Carlos Macaya, Antonio Fernández-Ortiz
BACKGROUND: Coronary aneurysms (1.5 times dilation the reference-vessel) are uncommon and have been diagnosed with increasing frequency with coronary angiography. The incidence varies from 1.5% to 5%. Reported complications are multiple: thrombosis, distal embolization, rupture and vasospasm, causing ischemia, heart failure or arrhythmias. However, the natural history and prognosis remains obscure. We aimed to describe the characteristics of acute patients with coronary aneurysms. METHODS: Prospective coronariography registry of patients with the diagnosis of coronary aneurysm between 2002 and 2013...
December 6, 2017: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://www.readbyqxmd.com/read/29275452/mild-troponin-elevation-in-patients-admitted-to-the-emergency-department-with-atrial-fibrillation-30-day-post-discharge-prognostic-significance
#5
João Augusto, Miguel Borges Santos, David Roque, Daniel Faria, Joana Urzal, José Morais, Victor Gil, Carlos Morais
Patients with atrial fibrillation (AF) often undergo troponin (Tn) testing in the emergency department (ED), but the clinical significance of mildly elevated values remains unclear. We evaluated short-term 30-day post-discharge outcomes in AF patients according to troponin levels. Out of 2181 AF patients evaluated in the ED (June 2014 to June 2015), we included consecutive admitted patients. Patients were grouped into those with normal Tn values (≤ 0.05 ng/mL), mild elevations (> 0.05-0.5 ng/mL, 10× URL) and marked elevations (> 0...
December 23, 2017: Internal and Emergency Medicine
https://www.readbyqxmd.com/read/29258913/evaluation-of-dyslipidaemia-and-the-impact-of-hypolipidemic-therapy-on-prognosis-in-high-and-very-high-risk-patients-through-the-hyperlipidaemia-therapy-in-tertiary-cardiological-center-tercet-registry
#6
Krzysztof Dyrbuś, Tadeusz Osadnik, Piotr Desperak, Aneta Desperak, Mariusz Gąsior, Maciej Banach
The use of statins in the treatment of hyperlipidaemia leads to a significant decrease in cardiovascular (CV) endpoints, and therapy effects are proportional to the reduction of cholesterol levels. In Poland, information about the effects of statin therapy is scarcely available. The information gathered in the Hyperlipidaemia Therapy in the tERtiary Cardiological cEnTer (TERCET) Registry on high-risk and very high-risk patients might improve our knowledge on this issue and help to introduce suitable activities...
December 16, 2017: Pharmacological Research: the Official Journal of the Italian Pharmacological Society
https://www.readbyqxmd.com/read/29249471/determinants-and-prognostic-impact-of-heart-failure-and-left-ventricular-ejection-fraction-in-acute-coronary-syndrome-settings
#7
Rosa Agra Bermejo, Alberto Cordero, José M García-Acuña, Inés Gómez Otero, Alfonso Varela Román, Álvaro Martínez, Leyre Álvarez Rodríguez, Charigan Abou-Jokh, Moisés Rodríguez-Mañero, Belén Cid Álvarez, Ramón López-Palop, Pilar Carrillo, José R González-Juanatey
INTRODUCTION AND OBJECTIVES: Contemporary data on the incidence and prognosis of heart failure (HF) and the influence of left ventricular ejection fraction (LVEF) in the setting of acute coronary syndrome (ACS) are scant. The aim of this study was to examine the relationship between LVEF and HF with long-term prognosis in a cohort of patients with ACS. METHODS: This is a retrospective observational study of 6208 patients consecutively admitted for ACS to 2 different Spanish hospitals...
December 14, 2017: Revista Española de Cardiología
https://www.readbyqxmd.com/read/29239257/cardiac-magnetic-resonance-assessment-of-diastolic-dysfunction-in-acute-coronary-syndrome
#8
Shah M Azarisman, Karen S Teo, Matthew I Worthley, Stephen G Worthley
Chest pain is an important presenting symptom. However, few cases of chest pain are diagnosed as acute coronary syndrome (ACS) in the acute setting. This results in frequent inappropriate discharge and major delay in treatment for patients with underlying ACS. The conventional methods of assessing ACS, which include electrocardiography and serological markers of infarct, can take time to manifest. Recent studies have investigated more sensitive and specific imaging modalities that can be used. Diastolic dysfunction occurs early following coronary artery occlusion and its detection is useful in confirming the diagnosis, risk stratification, and prognosis post-ACS...
December 2017: Journal of International Medical Research
https://www.readbyqxmd.com/read/29236216/long-term-outcomes-of-a%C3%A2-caucasian-cohort-presenting-with-acute-coronary-syndrome-and-or-out-of-hospital-cardiac-arrest-caused-by-coronary-spasm
#9
W Vlastra, M Piek, M A van Lavieren, M E J C Hassell, B E Claessen, G W Wijntjens, T P van de Hoef, K D Sjauw, M A Beijk, R Delewi, J J Piek
BACKGROUND: Coronary artery spasm may be the underlying mechanism in up to 10% of cases of acute coronary syndrome (ACS) and sudden cardiac death. Asian individuals exhibit a 3-times greater incidence of spasm than Caucasians; this is likely due to different types of mechanisms. Consequently, solid data is limited about the long-term prognosis in Caucasian patients presenting with ACS and/or out-of-hospital cardiac arrest (OHCA) caused by coronary spasm. METHODS: Between 2002 and 2015, thirty Caucasian patients with coronary artery spasm presenting with ACS (N = 29) and/or OHCA (N = 11) were enrolled in this prospective registry...
December 13, 2017: Netherlands Heart Journal
https://www.readbyqxmd.com/read/29226754/cardiac-troponins-25-years-on-the-stage-and-still-improving-their-clinical-value
#10
Aitor Alquézar-Arbé, Alessandro Sionis, Jorge Ordoñez-Llanos
Twenty-five years ago, non-isotopic immunoassays for measuring the cardiac specific isoforms of troponin I (cTnI) and T (cTnT) were developed. Both biomarkers radically changed the diagnosis, prognosis, and therapy indication of acute coronary syndromes (ACS) and, particularly, of myocardial infarction (MI). However, cardiac troponins (cTn) rapidly demonstrated their usefulness in other cardiac and non-cardiac conditions, a part of the ischemic coronary diseases. Consequently, the number of patients to be tested for cTn and the number of tests requested to clinical laboratories sharply increased...
December 11, 2017: Critical Reviews in Clinical Laboratory Sciences
https://www.readbyqxmd.com/read/29215707/the-diagnostic-and-prognostic-value-of-circulating-micrornas-in-coronary-artery-disease-a-novel-approach-to-disease-diagnosis-of-stable-cad-and-acute-coronary-syndrome
#11
REVIEW
Seyed Mostafa Parizadeh, Gordon A Ferns, Maryam Ghandehari, Seyed Mahdi Hasanian, Majid Ghayour-Mobarhan, Seyed Mohammad Reza Parizadeh, Amir Avan
Coronary artery disease (CAD) is the most common manifestation of CVD and the acute coronary syndrome (ACS) is associated with a substantial morbidity and mortality in most populations globally. There are several biomarkers for diagnosis of MI. Troponin is routinely used as a biomarker in patients with chest pain, but it lacks sensitivity in the first hours of onset of symptoms, and so there is still a clinical need for new biomarkers for the diagnosis of CAD events. Recent studies have shown that miRNAs are involved in atherosclerotic plaque formation and their expression is altered during CAD events...
December 7, 2017: Journal of Cellular Physiology
https://www.readbyqxmd.com/read/29208858/correlation-of-troponin-i-level-with-left-ventricular-ejection-fraction-and-in-hospital-outcomes-after-first-attack-of-non-st-segment-elevation-myocardial-infarction
#12
M H Khan, M N Islam, G P Aditya, M Z Islam, A S Bhuiyan, B Saha, K Bhowmick, M Hassan, P K Paul, S Chowdhury, R Rahman
Coronary heart disease (CHD) is the most common cause of heart disease and is the single most important cause of premature death in developed world. Recognizing a patient with ACS is important because the diagnosis triggers both triage and management. cTnI is 100% tissue-specific for the myocardium and it has been shown to be a very sensitive and specific marker for acute myocardial infarction (AMI). Ventricular function is the best predictor of death after an acute coronary syndrome. It serves as a marker of myocardial damage, provides information on systolic function as well as diagnosis and prognosis...
October 2017: Mymensingh Medical Journal: MMJ
https://www.readbyqxmd.com/read/29199266/diagnosis-and-management-of-spontaneously-recanalized-coronary-thrombus-guided-by-optical-coherence-tomography%C3%A3-lessons-from-the-french-lotus-root-registry
#13
Géraud Souteyrand, Mathieu Valladier, Nicolas Amabile, François Derimay, Brahim Harbaoui, Pierre Leddet, Pierre Barnay, Guilhem Malcles, Aurelien Mulliez, Colin Berry, Romain Eschalier, Nicolas Combaret, Pascal Motreff
BACKGROUND: Spontaneous reanalyzed coronary thrombus (SRCT) has been reported in autopsy series, but little is known about SRCT, and it is potentially under-diagnosed in clinical practice.Methods and Results:SRCT identified on OCT were included in a French multicenter series, the Lotus Root French Registry. A total of 34 SRCT were identified on OCT in 33 patients (23 male; median age, 56 years; IQR, 52-65 years); 23/33 patients (70%) presented with angina pectoris and/or dyspnea. Three angiographic aspects were distinguished retrospectively: braided, pseudo-dissected, and hazy...
December 1, 2017: Circulation Journal: Official Journal of the Japanese Circulation Society
https://www.readbyqxmd.com/read/29168653/utilizing-biomarkers-in-colorectal-cancer-an-interview-with-ajay-goel
#14
Ajay Goel
Ajay Goel, PhD, is a Professor and Director, Center for Gastrointestinal Research, and Director, Center for Translational Genomics and Oncology, at the Baylor Scott & White Research Institute, Baylor University Medical Center in Dallas, Texas. Dr Goel has spent more than 20 years researching cancer and has been the lead author or contributor to over 240 scientific articles published in peer-reviewed international journals and several book chapters. He is also a primary inventor on more than 15 international patents aimed at developing various biomarkers for the diagnosis, prognosis and prediction of gastrointestinal cancers...
November 23, 2017: Future Oncology
https://www.readbyqxmd.com/read/29153753/an-easy-assessment-of-frailty-at-baseline-independently-predicts-prognosis-in-very-elderly-patients-with-acute-coronary-syndromes
#15
Oriol Alegre, Francesc Formiga, Ramón López-Palop, Francisco Marín, María T Vidán, Manuel Martínez-Sellés, Antoni Carol, Alessandro Sionis, Pablo Díez-Villanueva, Jaime Aboal, Anna Palau-Vendrel, Héctor Bueno, Angel Perez Rivera, Juan Sanchís, Emad Abu-Assi, Miguel Corbí, Juan C Castillo, Jordi Bañeras, Violeta González-Salvado, Àngel Cequier, Albert Ariza-Solé
BACKGROUND: Information about the impact of frailty in patients with acute coronary syndromes (ACS) is scarce. No study has assessed the prognostic impact of frailty as measured by the FRAIL scale in very elderly patients with ACS. METHODS: The prospective multicenter LONGEVO-SCA registry included unselected patients with ACS aged 80 years or older. A comprehensive geriatric assessment was performed during hospitalization, including frailty assessment by the FRAIL scale...
November 16, 2017: Journal of the American Medical Directors Association
https://www.readbyqxmd.com/read/29153450/is-external-fixation-needed-for-the-treatment-of-tibial-fractures-with-acute-compartment-syndrome
#16
Tae Hun Kim, Jun Young Chung, Keun Su Kim, Hyung Keun Song
Acute compartment syndrome (ACS) after tibial fracture carries a risk of various complications, including infection, delayed union, nonunion, nerve damage, and poor prognosis. For the treatment of fractures with ACS, fasciotomy is conducted, and the method to stabilise the fracture has to be considered. Thirty-five patients who underwent surgery for ACS with tibial shaft fractures were evaluated, and the results of initial internal fixation (Group I, 20 patients) and initial external fixation (Group II, 15 patients) were analysed...
November 16, 2017: Injury
https://www.readbyqxmd.com/read/29131293/dynamic-thiol-disulfide-homeostasis-and-its-prognostic-value-in-patients-with-non-st-elevation-acute-coronary-syndromes
#17
Serkan Sivri, Hacı Ahmet Kasapkara, Melike Polat, Yakup Alsancak, Tahir Durmaz, Özcan Erel, Engin Bozkurt
BACKGROUND: Cardiovascular diseases are still one of the leading causes of death in industrialized countries, and oxidative stress plays an important role in the pathogenesis of acute coronary syndromes (ACS). The dynamic thiol/disulfide homeostasis has an important role in maintaining the oxidant-antioxidant balance. AIM: We aimed to demonstrate the relationship between dynamic thiol/disulfide homeostasis parameters and non-ST elevation ACS (NSTE-ACS). METHODS: The patients with NSTE-ACS (n:210) and a control group (n:185) were included in the study...
November 13, 2017: Kardiologia Polska
https://www.readbyqxmd.com/read/29128315/parathyroid-hormone-calcidiol-calcitriol-and-adverse-events-in-the-acute-coronary-syndrome
#18
P Ramos Ruiz, L Jaulent Huertas, M Castañeda Sancirilo, J J Martínez Díaz, G Clavel Ruipérez, L García de Guadiana Romualdo, S Wasniewski, M Merelo Nicolás, I García Escribano, F Soria Arcos, J A Castillo Moreno, L Consuegra Sánchez
OBJECTIVE: To know the clinical profile as well as the prognostic significance of elevated levels of parathyroid hormone (PTH) in patients admitted for acute coronary syndrome (ACS). DESIGN AND SETTING: Observational and prospective study of patients admitted for ACS in a single Spanish center during a period of six months. INTERVENTION AND VARIABLES OF INTEREST: The circulating concentrations of PTH, calcidiol, calcitriol, NT-proBNP, C-reactive protein, cystatinC and fibrinogen were determined within the first 48h at admission...
November 8, 2017: Medicina Intensiva
https://www.readbyqxmd.com/read/29124521/successful-peritoneal-dialysis-using-a-percutaneous-tube-for-peritoneal-drainage-in-an-extremely-low-birth-weight-infant-a-case-report
#19
Satoshi Yokoyama, Takayuki Nukada, Yuka Ikeda, Shigeto Hara, Akira Yoshida
BACKGROUND: Peritoneal dialysis (PD) for acute kidney injury (AKI) of newborns has been performed safely. AKI occurs in 8 to 24% of extremely low birth weight (ELBW) infants. Although PD has only been used occasionally in ELBW infants, prognosis is poor for ELBW infants with AKI. Several reports have described successful PD in these infants, but no guideline-based evidence concerning indications for renal replacement therapy in ELBW infants are currently available. Here, we report on our experience with PD in an ELBW infant with AKI resulting from septic shock...
November 9, 2017: Surgical Case Reports
https://www.readbyqxmd.com/read/29121808/the-prognostic-value-of-lipoprotein-associated-phospholipase-a2-in-the-long-term-care-of-patients-with-acute-coronary-syndrome-undergoing-percutaneous-coronary-intervention
#20
Lijiao Yang, Hong Wang, Yida Zhang, Tingting Han, Wenfeng Wang
Lipoprotein-associated phospholipase A2 (Lp-PLA2) is an independent risk factor for cardiovascular disease. Accordingly, studies from many countries around the world have shown an association between Lp-PLA2 and cardiovascular events in patients with acute coronary syndrome (ACS) undergoing percutaneous coronary intervention (PCI), but this association has not been documented among the Chinese. The aim of this study was to assess the use of Lp-PLA2 as a useful marker for predicting the long-term prognosis of Chinese patients with ACS undergoing PCI...
January 1, 2017: Clinical and Applied Thrombosis/hemostasis
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