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https://www.readbyqxmd.com/read/28723281/imaging-correlates-of-adult-glioma-genotypes
#1
Marion Smits, Martin J van den Bent
Primary brain tumors, most commonly gliomas, are histopathologically typed and graded as World Health Organization (WHO) grades I-IV according to increasing degrees of malignancy. These grades provide prognostic information and guidance on treatment such as radiation therapy and chemotherapy after surgery. Despite the confirmed value of the WHO grading system, results of a multitude of studies and prospective interventional trials now indicate that tumors with identical morphologic criteria can have highly different outcomes...
August 2017: Radiology
https://www.readbyqxmd.com/read/28721330/truebeam-radiosurgery-for-the-treatment-of-trigeminal-neuralgia-preliminary-results-at-a-single-institution
#2
Mena G Kerolus, Neilayan Sen, Sonal Mayekar, Alistar Templeton, Julius Turian, Aidnag Diaz, Lorenzo Munoz, Richard W Byrne, Sepehr Sani
INTRODUCTION: Radiosurgery is now an established method of satisfactory pain control in patients with trigeminal neuralgia (TN). The Varian Truebeam STx (Varian Medical Systems, Palo Alto, CA) linear accelerator (LINAC) system is an arc-based, frameless stereotactic radiosurgery system used for the treatment of TN. To our knowledge, there has been only one published series of patient histories that documents the use of a frameless LINAC system for the treatment of TN. We describe the treatment parameters, patient outcomes, and complications associated with the treatment of TN...
June 16, 2017: Curēus
https://www.readbyqxmd.com/read/28718441/is-intra-articular-steroid-injection-to-the-temporomandibular-joint-for-juvenile-idiopathic-arthritis-more-effective-and-efficient-when-performed-with-image-guidance
#3
Cory M Resnick, Pouya M Vakilian, Leonard B Kaban, Zachary S Peacock
PURPOSE: To compare short-term outcomes and procedure times for intra-articular steroid injection (IASI) to the temporomandibular joint (TMJ) with and without the use of intraoperative image guidance for patients with juvenile idiopathic arthritis (JIA). MATERIALS AND METHODS: This is a retrospective study of children with JIA who underwent TMJ IASI at Boston Children's Hospital (Boston, MA). Patients were divided into groups according to IASI technique: 1) "landmark" group if performed by an oral and maxillofacial surgeon using an anatomic landmark technique with no intraoperative image guidance or 2) "image-guided" group if performed by an interventional radiologist using intraoperative ultrasound and computed tomography...
April 2017: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28718001/a-new-device-for-fiducial-registration-of-image-guided-navigation-system-for-liver-rfa
#4
Nobutaka Doba, Hiroyuki Fukuda, Kazushi Numata, Yoshiteru Hao, Kouji Hara, Akito Nozaki, Masaaki Kondo, Makoto Chuma, Katsuaki Tanaka, Shigeo Takebayashi, Norihiro Koizumi, Akira Kobayashi, Junichi Tokuda, Shin Maeda
PURPOSE: Radiofrequency ablation for liver tumors (liver RFA) is widely performed under ultrasound guidance. However, discriminating between the tumor and the needle is often difficult because of cavitation caused by RFA-induced coagulation. An unclear ultrasound image can lead to complications and tumor residue. Therefore, image-guided navigation systems based on fiducial registration have been developed. Fiducial points are usually set on a patient's skin. But the use of internal fiducial points can improve the accuracy of navigation...
July 17, 2017: International Journal of Computer Assisted Radiology and Surgery
https://www.readbyqxmd.com/read/28717564/electrically-tunable-fluidic-lens-imaging-system-for-laparoscopic-fluorescence-guided-surgery
#5
Davide Volpi, Iain D C Tullis, Paul R Barber, Edyta M Augustyniak, Sean C Smart, Katherine A Vallis, Borivoj Vojnovic
The addition of fluorescence guidance in laparoscopic procedures has gained significant interest in recent years, particularly through the use of near infrared (NIR) markers. In this work we present a novel laparoscope camera coupler based on an electrically tunable fluidic lens that permits programmable focus control and has desirable achromatic performance from the visible to the NIR. Its use extends the lower working distance limit and improves detection sensitivity, important for work with molecularly targeted fluorescence markers...
July 1, 2017: Biomedical Optics Express
https://www.readbyqxmd.com/read/28716213/imaging-of-endoscopic-approaches-to-the-anterior-and-central-skull-base
#6
REVIEW
I M Schmalfuss
Sinonasal endoscopy for treatment of benign sinonasal diseases is a well-established procedure. Recent advances in endoscope technology have substantially expanded its application with many institutions now offering resection of skull base lesions and sinonasal malignancies via the endoscopic approach. Its minimally invasive nature leads to faster recovery time, better cosmetic results, and fewer complications. Unfortunately, not all lesions involving the sinonasal region and skull base are accessible to sinonasal endoscopy...
July 14, 2017: Clinical Radiology
https://www.readbyqxmd.com/read/28713309/associations-among-different-internet-access-time-gender-and-cyberbullying-behaviors-in-taiwan-s-adolescents
#7
Cheng-Min Chao, Tai-Kuei Yu
With the increasing convenience of social networking sites and their interconnectedness with human interaction, verbal and image bullying have turned digital, making cyberbullying a new form of bullying attracting the attention of researchers, social workers, and schools. This study focuses on the status quo of attitude toward cyberbullying and cyberbullying behavior, explores associations of attitude toward behavior on cyberbullying behavior in gender and different internet access times. In a cross-sectional survey, adolescents were surveyed through self-report questionnaires, 13,864 respondents were received among 150 high schools in Taiwan...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28710894/short-frontal-plane-fractures-involving-the-dorsoproximal-articular-surface-of-the-proximal-phalanx-description-of-the-injury-and-a-technique-for-repair
#8
I M Wright, G Minshall
BACKGROUND: Chip fractures of the dorsoproximal articular margin of the proximal phalanx are common injuries in racehorses. Large fractures can extend distal to the joint capsule insertion and have been described as dorsal frontal fractures. OBJECTIVES: To report the location and morphology of short frontal plane fractures involving the dorsoproximal articular surface of the proximal phalanx and to describe a technique for repair under arthroscopic and radiographic guidance...
July 15, 2017: Equine Veterinary Journal
https://www.readbyqxmd.com/read/28710605/current-clinical-applications-of-coronary-optical-coherence-tomography
#9
REVIEW
Teruyoshi Kume, Shiro Uemura
Optical coherence tomography (OCT) is an intra-coronary diagnostic technique that provides detailed imagings of blood vessels in the current cardiac catheterization laboratory. The higher resolution of OCT often provides superior delineation of each structure compared with intravascular ultrasound (IVUS), and it can reliably visualize the microstructure of normal and diseased arteries. The capabilities of OCT are well suited for the identification of calcified plaque and neointima formation after stent implantation...
July 14, 2017: Cardiovascular Intervention and Therapeutics
https://www.readbyqxmd.com/read/28710227/advancing-concussion-assessment-in-pediatrics-a-cap-a-prospective-concurrent-cohort-longitudinal-study-of-mild-traumatic-brain-injury-in-children-protocol-study
#10
Keith Owen Yeates, Miriam Beauchamp, William Craig, Quynh Doan, Roger Zemek, Bruce Bjornson, Jocelyn Gravel, Angelo Mikrogianakis, Bradley Goodyear, Nishard Abdeen, Christian Beaulieu, Mathieu Dehaes, Sylvain Deschenes, Ashley Harris, Catherine Lebel, Ryan Lamont, Tyler Williamson, Karen Maria Barlow, Francois Bernier, Brian L Brooks, Carolyn Emery, Stephen B Freedman, Kristina Kowalski, Kelly Mrklas, Lianne Tomfohr-Madsen, Kathryn J Schneider
INTRODUCTION: Paediatric mild traumatic brain injury (mTBI) is a public health burden. Clinicians urgently need evidence-based guidance to manage mTBI, but gold standards for diagnosing and predicting the outcomes of mTBI are lacking. The objective of the Advancing Concussion Assessment in Pediatrics (A-CAP) study is to assess a broad pool of neurobiological and psychosocial markers to examine associations with postinjury outcomes in a large sample of children with either mTBI or orthopaedic injury (OI), with the goal of improving the diagnosis and prognostication of outcomes of paediatric mTBI...
July 13, 2017: BMJ Open
https://www.readbyqxmd.com/read/28710046/image-guidance-to-aid-pedicle-screw-fixation-of-a-lumbar-fracture-dislocation-injury-in-a-toddler
#11
John K Houten, Jonathan Nahkla, Shashank Ghandi
BACKGROUND: Pedicle screw fixation of the lumbar spine in children less than two years of age is particularly challenging, as successful cannulation of the small pedicle dimensions require a high level of precision and there are no implants specifically designed for the infantile spine. Image-guided navigation is commonly used in adult spinal surgery and may be particularly helpful for placement of spinal screws where the bony anatomy is small and/or anatomically complex as in the upper cervical area...
July 11, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28710005/cationic-microbubbles-and-antibiotic-free-miniplasmid-for-sustained-ultrasound-mediated-transgene-expression-in-liver
#12
Simona Manta, Gilles Renault, Anthony Delalande, Olivier Couture, Isabelle Lagoutte, Johanne Seguin, Franck Lager, Pascal Houzé, Patrick Midoux, Michel Bessodes, Daniel Scherman, Michel-Francis Bureau, Corinne Marie, Chantal Pichon, Nathalie Mignet
Despite the increasing number of clinical trials in gene therapy, no ideal methods still allow non-viral gene transfer in deep tissues such as the liver. We were interested in ultrasound (US)-mediated gene delivery to provide long term liver expression. For this purpose, new positively charged microbubbles were designed and complexed with pFAR4, a highly efficient small length miniplasmid DNA devoid of antibiotic resistance sequence. Sonoporation parameters, such as insonation time, acoustic pressure and duration of plasmid injection were controlled under ultrasound imaging guidance...
July 11, 2017: Journal of Controlled Release: Official Journal of the Controlled Release Society
https://www.readbyqxmd.com/read/28709984/micrometer-scale-guidance-of-mesenchymal-stem-cells-to-form-structurally-oriented-large-scale-tissue-engineered-cartilage
#13
Chih-Ling Chou, Alexander L Rivera, Valencia Williams, Jean F Welter, Joseph M Mansour, Judith A Drazba, Takao Sakai, Harihara Baskaran
Current clinical methods to treat articular cartilage lesions provide temporary relief of the symptoms but fail to permanently restore the damaged tissue. Tissue engineering, using mesenchymal stem cells (MSCs) combined with scaffolds and bioactive factors, is viewed as a promising method for repairing cartilage injuries. However, current tissue engineered constructs display inferior mechanical properties compared to native articular cartilage, which could be attributed to the lack of structural organization of the extracellular matrix (ECM) of these engineered constructs in comparison to the highly oriented structure of articular cartilage ECM...
July 11, 2017: Acta Biomaterialia
https://www.readbyqxmd.com/read/28708652/clinical-application-of-multimodal-neuronavigation-system-in-neuroendoscope-assisted-skull-base-chordoma-resection
#14
Xin Wang, Long Li, Yibao Wang, Jinqu Hu, Jinpeng Zhou, Zhitao Jing, Anhua Wu
Skull base chordoma is a rare tumor arising from embryonic remnants of the notochord with invasive potential. Due to the destruction of osseous landmarks and invasion of surrounding structures, surgical resection is challenging. The authors explored the clinical value of a multimodal neuronavigation system in skull base chordoma resection using a neuroendoscope. Between January 2012 and January 2016, the authors utilized neuroendoscopy to excise skull base chordoma in 93 patients. The authors performed 45 operations assisted by multimodal neuronavigation (neuronavigation group) and 48 without intraoperative imaging guidance (control group)...
July 13, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28707807/accuracy-of-computer-assisted-navigation-significant-augmentation-by-facial-recognition-software
#15
Jordan T Glicksman, Christine Reger, Arjun K Parasher, David W Kennedy
BACKGROUND: Over the past 20 years, image guidance navigation has been used with increasing frequency as an adjunct during sinus and skull base surgery. These devices commonly utilize surface registration, where varying pressure of the registration probe and loss of contact with the face during the skin tracing process can lead to registration inaccuracies, and the number of registration points incorporated is necessarily limited. The aim of this study was to evaluate the use of novel facial recognition software for image guidance registration...
July 14, 2017: International Forum of Allergy & Rhinology
https://www.readbyqxmd.com/read/28707540/commentary-on-duty-of-candour-and-cancer-screening
#16
Rosalind Given-Wilson
English law mandates a duty of candour (DOC) for all healthcare providers. They must be open and honest when something goes wrong with care causing harm. Providers must apologise to those affected and investigate what happened. Screening is not 100% accurate and false positive and false negative results are inevitable. Guidance on DOC assists providers to judge when something has gone wrong in screening and the DOC legislation applies. DOC guidance helps to distinguish such incidents from harms which are an expected and inevitable consequence of the imperfections of screening tests...
July 14, 2017: British Journal of Radiology
https://www.readbyqxmd.com/read/28707525/is-there-a-role-for-ultrasound-guided-sialoplasty-in-the-management-of-salivary-duct-strictures
#17
Jimmy Makdissi, Lee Feinberg, Amit Roy
Ductal stricture is a common cause of obstructive salivary gland disease. Balloon dilatation of the parotid duct as a minimally invasive technique is currently carried out under fluoroscopic guidance or during sialendocopy. We present a case report of ultrasound guided balloon dilatation. A 45 year old lady presented with a long history of obstructive symptoms affecting the right parotid gland. Ultrasound examination revealed a tortuous right main parotid duct with marked dilatation throughout its course and multiple sites of focal stricture formation...
July 14, 2017: Dento Maxillo Facial Radiology
https://www.readbyqxmd.com/read/28707500/noninvasive-imaging-of-immune-checkpoint-ligand-pd-l1-in-tumors-and-metastases-for-guiding-immunotherapy
#18
Samit Chatterjee, Wojciech G Lesniak, Sridhar Nimmagadda
Immunotherapy holds great promise in cancer treatment. The challenges in advancing immunotherapies lie in patient stratification and monitoring therapy. Noninvasive detection of immune checkpoint ligand PD-L1 can serve as an important biomarker for guidance and monitoring of immunotherapy. Here in, we provide an overview of our efforts to develop clinically translatable PD-L1-specific imaging agents for quantitative and real-time assessment of PD-L1 expression in tumor microenvironment.
January 2017: Molecular Imaging
https://www.readbyqxmd.com/read/28705490/deformation-correction-for-image-guided-liver-surgery-an%C3%A2-intraoperative-assessment-of%C3%A2-fidelity
#19
Logan W Clements, Jarrod A Collins, Jared A Weis, Amber L Simpson, T Peter Kingham, William R Jarnagin, Michael I Miga
BACKGROUND: Although systems of 3-dimensional image-guided surgery are a valuable adjunct across numerous procedures, differences in organ shape between that reflected in the preoperative image data and the intraoperative state can compromise the fidelity of such guidance based on the image. In this work, we assessed in real time a novel, 3-dimensional image-guided operation platform that incorporates soft tissue deformation. METHODS: A series of 125 alignment evaluations were performed across 20 patients...
July 10, 2017: Surgery
https://www.readbyqxmd.com/read/28702337/linear-ebus-guided-fiducial-marker-placement-to-guide-radiotherapy-for-endobronchial-radiographically-occult-synchronous-primary-squamous-cell-carcinoma-of-the-lung
#20
David Maurice Chambers, Gregory John Pfister, Umair Ahmad Gauhar
Radiation therapy has emerged as a useful alternative therapy for patients with early-stage, non-resectable lung cancer. In patients whose malignancies are difficult to localize on computed tomography imaging, such therapy becomes difficult. Fiducial markers are frequently placed in peripheral pulmonary lesions to assist radiation therapy. Although placement of markers under linear endobronchial ultrasonography within mediastinal and hilar lymph nodes has been reported, no strategy has been described to assist radiotherapy of purely endobronchial tumors...
2017: Respiratory Medicine Case Reports
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