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https://www.readbyqxmd.com/read/28645836/percutaneous-treatment-of-the-tricuspid-valve-disease-new-hope-for-the-forgotten-valve
#1
Francisco Campelo-Parada, Olivier Lairez, Didier Carrié
Tricuspid valve disease is a frequent condition but is currently undertreated. A limited number of patients undergo an isolated surgical tricuspid repair, and this intervention is associated with poor outcomes, especially in patients with previous cardiac surgery. Most patients are only medically treated, despite the impact of severe tricuspid regurgitation on functional status and long-term survival. Transcatheter therapies represent a promising alternative for patients with severe tricuspid regurgitation and high surgical risk...
June 20, 2017: Revista Española de Cardiología
https://www.readbyqxmd.com/read/28645214/sodium-fluorescein-facilitates-guided-sampling-of-diagnostic-tumor-tissue-in-nonenhancing-gliomas
#2
Stephen G Bowden, Justin A Neira, Brian J A Gill, Timothy H Ung, Zachary K Englander, George Zanazzi, Peter D Chang, Jorge Samanamud, Jack Grinband, Sameer A Sheth, Guy M McKhann, Michael B Sisti, Peter Canoll, Randy S D'Amico, Jeffrey N Bruce
BACKGROUND: Accurate tissue sampling in nonenhancing (NE) gliomas is a unique surgical challenge due to their intratumoral histological heterogeneity and absence of contrast enhancement as a guide for intraoperative stereotactic guidance. Instead, T2/fluid-attenuated inversion-recovery (FLAIR) hyperintensity on MRI is commonly used as an imaging surrogate for pathological tissue, but sampling from this region can yield nondiagnostic or underdiagnostic brain tissue. Sodium fluorescein is an intraoperative fluorescent dye that has a high predictive value for tumor identification in areas of contrast enhancement and NE in glioblastomas...
June 21, 2017: Neurosurgery
https://www.readbyqxmd.com/read/28643467/a-core-shell-satellite-structured-fe3-o4-g-c3-n4-ucnps-peg-for-t1-t2-weighted-dual-modal-mri-guided-photodynamic-therapy
#3
Lili Feng, Dan Yang, Fei He, Shili Gai, Chunxia Li, Yunlu Dai, Piaoping Yang
Reactive oxygen species (ROS) produced in the specific tumor site plays the key role in photodynamic therapy (PDT). Herein, a multifunctional nanoplatform is designed by absorbing ultrasmall upconversion nanoparticles (UCNPs) on mesoporous graphitic-phase carbon nitride (g-C3 N4 ) coated superparamagnetic iron oxide nanospheres, then further modified with polyethylene glycol (PEG)molecules (abbreviated as Fe3 O4 @g-C3 N4 -UCNPs-PEG). The inert g-C3 N4 layer between Fe3 O4 core and outer UCNPs can substantially depress the quenching effect of Fe3 O4 on the upconversion emission...
June 23, 2017: Advanced Healthcare Materials
https://www.readbyqxmd.com/read/28643319/-progress-of-the-application-of-optical-coherence-tomography-in-gastrointestinal-tumor-surgery
#4
Yongsheng Li, Hao Liu, Haipeng Huang, Yu Zhu, Haijun Deng, Jiang Yu, Site Luo, Li Huo, Li Lin, Huikai Xie, Guoxin Li
Optical coherence tomography (OCT) is a real-time, cross-sectional optical imaging technology. It is analogous to ultrasonography, except that OCT uses light waves instead of sound waves, and can provide three-dimensional morphological images of living tissues with a micrometer resolution. Through the use of endoscopes, needles, catheters and laparoscopes, OCT has demonstrated tremendous imaging potential in tumor surgery. The current studies suggest that OCT has potential for clinical applications in the following fields of gastrointestinal tumor surgery: (1) Early tumor detection and diagnosis: OCT can distinguish differences between polyp tissue, normal tissue and malignant tissue...
June 25, 2017: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/28642004/removal-of-entrapped-transoesophageal-echocardiography-probe-under-the-guidance-of-fluoroscopic-imaging
#5
Ki-Hun Kim, Sang-Hoon Seol, Yun-Seok Song, Dong-Kie Kim, Doo-Il Kim
No abstract text is available yet for this article.
May 29, 2017: Heart, Lung & Circulation
https://www.readbyqxmd.com/read/28641464/ultrasound-guided-hydrodissection-for-assisting-percutaneous-microwave-ablation-of-renal-cell-carcinomas-adjacent-to-intestinal-tracts-a-preliminary-clinical-study
#6
Zhigang Cheng, Xiaoling Yu, Zhiyu Han, Fangyi Liu, Jie Yu, Ping Liang
PURPOSE: To evaluate the safety and efficacy of the clinical application of hydrodissection under ultrasound (US) guidance for assisting percutaneous microwave ablation (MWA) for the treatment of renal cell carcinomas (RCCs) adjacent to the intestinal tract. MATERIALS AND METHODS: From April 2014 to December 2016, clinical data from 24 patients with 25 RCCs were retrospectively analysed. Percutaneous MWA under the assistance of US-guided hydrodissection were performed to treat RCCs with a mean maximal diameter of 3...
June 22, 2017: International Journal of Hyperthermia
https://www.readbyqxmd.com/read/28639848/intraoperative-correction-of-femoral-rotational-deformity-using-a-conventional-navigation-system-and-a-smartphone-a-novel-technique
#7
Jia-Qing Cao, Jing-Huan Huang, Ting Yuan, Wei-Tao Jia, Hong Gao
The intraoperatively rotational control of femoral shaft fractures treated with a closed intramedullary interlocking nailing is a challenging problem. A novel surgical technique that includes respective insertions of guidewires into the proximal and distal femur under the guidance of a 2-dimensional fluoroscopy-based navigation system and the measurements of the intersection angle subtended by the proximal and distal guidewires with the smartphone positional software has been designed to provide intraoperatively quantitative parameters of femoral rotation deformation...
June 1, 2017: Surgical Innovation
https://www.readbyqxmd.com/read/28638915/-optogenetic-activation-of-dorsal-hippocampal-astrocytic-rac1-blocks-the-learning-of-associative-memory
#8
Xiao-Mu Guo, Zhao-Hui Liao, Ye-Zheng Tao, Fei-Fei Wang, Lan Ma
Rac1 belongs to the family of Rho GTPases, and plays important roles in the brain function. It affects the cell migration and axon guidance via regulating the cytoskeleton and cellular morphology. However, the effect of its dynamic activation in regulating physiological function remains unclear. Recently, a photoactivatable analogue of Rac1 (PA-Rac1) has been developed, allowing the activation of Rac1 by the specific wavelength of light in living cells. Thus, we constructed recombinant adeno-associated virus (AAV) of PA-Rac1 and its light-insensitive mutant PA-Rac1-C450A under the control of the mouse glial fibrillary acidic protein (mGFAP) promoter to manipulate Rac1 activity in astrocytes by optical stimulation...
June 25, 2017: Sheng Li Xue Bao: [Acta Physiologica Sinica]
https://www.readbyqxmd.com/read/28638802/target-migration-from-re-inflation-of-adjacent-atelectasis-during-lung-stereotactic-body-radiotherapy
#9
Bijing Mao, Vivek Verma, Dandan Zheng, Xiaofeng Zhu, Nathan R Bennion, Abhijeet R Bhirud, Maria A Poole, Weining Zhen
Stereotactic body radiotherapy (SBRT) is a widely accepted option for the treatment of medically inoperable early-stage non-small cell lung cancer (NSCLC). Herein, we highlight the importance of interfraction image guidance during SBRT. We describe a case of early-stage NSCLC associated with segmental atelectasis that translocated 15 mm anteroinferiorly due to re-expansion of the adjacent segmental atelectasis following the first fraction. The case exemplifies the importance of cross-sectional image-guided radiotherapy that shows the intended target, as opposed to aligning based on rigid anatomy alone, especially in cases associated with potentially "volatile" anatomic areas...
June 10, 2017: World Journal of Clinical Oncology
https://www.readbyqxmd.com/read/28638483/thermoacoustic-imaging-and-therapy-guidance-based-on-ultra-short-pulsed-microwave-pumped-thermoelastic-effect-induced-with-superparamagnetic-iron-oxide-nanoparticles
#10
Liewei Wen, Sihua Yang, Junping Zhong, Quan Zhou, Da Xing
Multifunctional nanoparticle-mediated imaging and therapeutic techniques are promising modalities for accurate localization and targeted treatment of cancer in clinical settings. Thermoacoustic (TA) imaging is highly sensitive to detect the distribution of water, ions or specific nanoprobes and provides excellent resolution, good contrast and superior tissue penetrability. TA therapy is a potential non-invasive approach for the treatment of deep-seated tumors. In this study, human serum albumin (HSA)-functionalized superparamagnetic iron oxide nanoparticle (HSA-SPIO) is used as a multifunctional nanoprobe with clinical application potential for MRI, TA imaging and treatment of tumor...
2017: Theranostics
https://www.readbyqxmd.com/read/28635233/-clinical-characteristics-and-prognosis-of-anaplastic-thyroid-carcinoma
#11
J F Wang, X H Zhu, Z Tan, M H Ge
Objective: To investigate the clinical characteristics, treatment outcomes and prognostic factors in patients with anaplastic thyroid cancer. Methods: Clinical data of 56 patients with anaplastic thyroid cancer at Zhejiang Cancer Hospital from January 2006 to June 2016 were retrospectively reviewed and followed up. Results: Of the 56 patients, there were 24 male and 32 female. The median age was 65 years old. At diagnosis, 10 patients have different degrees of breathing difficulty; 8 patients have varying degrees of dysphagia, and 12 patients have hoarseness...
June 23, 2017: Zhonghua Zhong Liu za Zhi [Chinese Journal of Oncology]
https://www.readbyqxmd.com/read/28633595/central-venous-catheter-insertion-into-the-false-lumen-of-a-complicated-aortic-dissection
#12
Ahmet Bas, Deniz Goksedef, Sedat G Kandemirli, Fatih Gulsen, Furuzan Numan
Thoracic endovascular repair is considered the first-line treatment in complicated acute type B dissection. Central venous catheters provide valuable vascular access during endovascular treatments. However, central venous catheters are not without complications. Herein, we report a case of central venous catheter insertion into the false lumen of a complicated acute type B aortic dissection by direct aortic puncture. The tip of the central venous catheter was in the false lumen. The central venous catheter was left in place initially and was removed after graft stent deployment...
January 1, 2017: Scottish Medical Journal
https://www.readbyqxmd.com/read/28627007/optical-molecular-imaging-guided-radiation-therapy-part-1-integrated-x-ray-and-bioluminescence-tomography
#13
Junwei Shi, Thirupandiyur S Udayakumar, Zhiqun Wang, Nesrin Dogan, Alan Pollack, Yidong Yang
PURPOSE: X-ray CT faces challenges in differentiating tumors from surrounding healthy tissues. A bioluminescence tomography (BLT) system which can directly reconstruct the internal luminescent tumors, was developed and integrated with CT system to accurately guide radiation dose delivery. METHODS: The BLT system, employing a lens-coupled CCD camera, was physically registered with an onboard cone beam CT system in an image guided small animal arc radiation treatment system (iSMAART)...
June 19, 2017: Medical Physics
https://www.readbyqxmd.com/read/28622797/making-the-best-value-of-clinical-radiology-irefer-guidelines-8th-edition
#14
D Remedios, B France, M Alexander
New uses of medical imaging as well as over-diagnosis and wasteful imaging have led to a 10% per annum growth in computed tomography (CT) and magnetic resonance imaging (MRI). Personalised value to the patient will be helped by referral guidelines for the best test first, adding evidence-based technical value to the investigation to answer the clinical question, thus providing allocative value to the commissioners of medical imaging. Appropriate imaging is driven by the need for effective decisions, radiation safety, and cost awareness...
June 13, 2017: Clinical Radiology
https://www.readbyqxmd.com/read/28621629/endoscopic-endonasal-odontoid-resection-with-real-time-intraoperative-image-guided-computed-tomography-report-of-4-cases
#15
Harminder Singh, Sarang Rote, Ajit Jada, Evan D Bander, Gustavo J Almodovar-Mercado, Walid I Essayed, Roger Härtl, Vijay K Anand, Theodore H Schwartz, Jeffrey P Greenfield
The authors present 4 cases in which they used intraoperative CT (iCT) scanning to provide real-time image guidance during endonasal odontoid resection. While intraoperative CT has previously been used as a confirmatory test after resection, to the authors' knowledge this is the first time it has been used to provide real-time image guidance during endonasal odontoid resection. The operating room setup, as well as the advantages and pitfalls of this approach, are discussed. A mobile intraoperative CT scanner was used in conjunction with real-time craniospinal neuronavigation in 4 patients who underwent endoscopic endonasal odontoidectomy for basilar invagination...
June 16, 2017: Journal of Neurosurgery
https://www.readbyqxmd.com/read/28621298/is-the-stella%C3%A2-5l-system-an-effective-cold-sterilization-technique-for-needle-based-confocal-miniprobes
#16
Cai-Xia Wang, Yuan-Yuan Chen, Feng Yang, Fan Yang, Jin-Tao Guo, Siyu Sun, Ling Fan
BACKGROUND AND OBJECTIVE: Needle-based confocal laser endomicroscopy (nCLE) under endoscopic ultrasound guidance is a newly developed imaging technique for pancreatic lesions and lymph nodes, enabling a subcellular level of resolution. The confocal miniprobe is an invasive instrument designed to be reused up to 10 times. Therefore, a method that ensures the complete elimination of microbial contaminants on the device is necessary. We studied the bactericidal efficacy of the Stella™ system, which purports to achieve this objective...
May 2017: Endoscopic Ultrasound
https://www.readbyqxmd.com/read/28618301/noninvasive-measurement-of-wave-speed-of-porcine-cornea-in-ex-vivo-porcine-eyes-for-various-intraocular-pressures
#17
Boran Zhou, Arthur J Sit, Xiaoming Zhang
The objective of this study was to extend an ultrasound surface wave elastography (USWE) technique for noninvasive measurement of ocular tissue elastic properties. In particular, we aim to establish the relationship between the wave speed of cornea and the intraocular pressure (IOP). Normal ranges of IOP are between 12 and 22mmHg. Ex vivo porcine eye balls were used in this research. The porcine eye ball was supported by the gelatin phantom in a testing container. Some water was pour into the container for the ultrasound measurement...
June 7, 2017: Ultrasonics
https://www.readbyqxmd.com/read/28617354/photoacoustic-drug-delivery
#18
REVIEW
Yuqi Zhang, Jicheng Yu, Anna R Kahkoska, Zhen Gu
Photoacoustic (PA) technology holds great potential in clinical translation as a new non-invasive bioimaging modality. In contrast to conventional optical imaging, PA imaging (PAI) enables higher resolution imaging with deeper imaging depth. Besides applications for diagnosis, PA has also been extended to theranostic applications. The guidance of PAI facilitates remotely controlled drug delivery. This review focuses on the recent development of PAI-mediated drug delivery systems. We provide an overview of the design of different PAI agents for drug delivery...
June 15, 2017: Sensors
https://www.readbyqxmd.com/read/28616275/transthoracic-echocardiography-is-a-safe-alternative-for-assessment-and-guidance-of-transcatheter-closure-of-secundum-atrial-septal-defect-in-children
#19
Alban-Elouen Baruteau, Sébastien Hascoët, Alain Fraisse
BACKGROUND: 2D-transesophageal echocardiography (TEE) is routinely performed to guide percutaneous ASD closure in children. We aimed to assess whether two-dimensional (2D)-transthoracic echocardiography (TTE) is a safe alternative for assessment and guidance of atrial septal defect (ASD) closure in unselected children. METHODS: We performed a retrospective single-center study including 389 consecutive children aged less than 15-year-old who underwent percutaneous ASD closure under 2D-TEE (1998-2005, n=133) or 2D-TTE (2005-2014, n=256)...
May 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28616236/effect-of-applied-energy-in-renal-sympathetic-denervation-with-magnetic-resonance-guided-focused-ultrasound-in-a-porcine-model
#20
Jill Shea, Joshua de Bever, Eugene Kholmovski, Hannah Beal, J Rock Hadley, Emilee Minalga, Mohamed E Salama, Nassir F Marrouche, Allison Payne
BACKGROUND: Past catheter-based and focused ultrasound renal denervation studies have indicated that procedure efficacy is related to the number of ablations performed or the amount of energy used for the ablation. This study extends those prior results and investigates energy level effects on the efficacy of MR guided focused ultrasound renal denervation performed in a porcine model. METHODS: Twenty-four normotensive pigs underwent unilateral denervation at three intensity levels...
2017: Journal of Therapeutic Ultrasound
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