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https://www.readbyqxmd.com/read/29140822/optimizing-pregnancy-treatment-interventions-for-moms-opti-mom-a-pilot-study
#1
Gerald T Cochran, Valerie Hruschak, Walitta Abdullah, Elizabeth Krans, Antoine B Douaihy, Stephanie Bobby, Rachel Fusco, Ralph Tarter
OBJECTIVES: The public health burden of opioid use disorder (OUD) among pregnant women has significantly increased in recent years. The Optimizing Pregnancy Treatment Interventions for Moms study was a pilot project that examined the feasibility of a patient navigation (PN) intervention model to reduce substance use and improve mental health, quality of life, and to increase engagement with treatment services among pregnant women with OUD. METHODS: A 1-group repeated-measures pilot study was conducted with treatment-seeking pregnant women with opioid dependence initiating buprenorphine maintenance treatment...
November 14, 2017: Journal of Addiction Medicine
https://www.readbyqxmd.com/read/29140816/the-role-of-small-incision-suture-less-cataract-surgery-in-the-developed-world
#2
Sanduk Ruit, Reeta Gurung, Shyam Vyas
PURPOSE OF REVIEW: Manual small incision cataract surgery (MSICS) has recently gone through much refinement and fine tuning. It is often taken as an alternate option for phacoemulsification, especially in developing country. This review will present some insight on its applications especially for developed nations. The role of MSCIS in tackling complex cataracts with stony hard nucleus is fairly established. The role of training residents with MSCIS has certain advantages though debatable...
November 14, 2017: Current Opinion in Ophthalmology
https://www.readbyqxmd.com/read/29138977/-reasons-for-delayed-and-discontinued-therapy-in-age-related-macular-degeneration
#3
M W M Wintergerst, J Bouws, J Loss, B Heimes, D Pauleikhoff, F G Holz, R P Finger
BACKGROUND: Critical prerequisites for successful therapy of neovascular age-related macular degeneration (nvAMD) are an early initiation and continuous monitoring; however, delays in starting therapy and non-medically indicated discontinuation of therapy are frequent, which limits therapy efficacy and, thus, visual outcomes. OBJECTIVE: To identify the reasons for delay in therapy and non-medically indicated termination of therapy. MATERIAL AND METHODS: Patients who had started a new therapy (starters) and those who independently terminated therapy (dropouts) were interviewed by telephone with a specific, standardized questionnaire...
November 14, 2017: Der Ophthalmologe: Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
https://www.readbyqxmd.com/read/29138692/transcriptomics-driven-lipidomics-tdl-identifies-the-microbiome-regulated-targets-of-ileal-lipid-metabolism
#4
Anirikh Chakrabarti, Mathieu Membrez, Delphine Morin-Rivron, Jay Siddharth, Chieh Jason Chou, Hugues Henry, Stephen Bruce, Sylviane Metairon, Frederic Raymond, Bertrand Betrisey, Carole Loyer, Scott J Parkinson, Mojgan Masoodi
The gut microbiome and lipid metabolism are both recognized as essential components in the maintenance of metabolic health. The mechanisms involved are multifactorial and (especially for microbiome) poorly defined. A strategic approach to investigate the complexity of the microbial influence on lipid metabolism would facilitate determination of relevant molecular mechanisms for microbiome-targeted therapeutics. E. coli is associated with obesity and metabolic syndrome and we used this association in conjunction with gnotobiotic models to investigate the impact of E...
2017: NPJ Systems Biology and Applications
https://www.readbyqxmd.com/read/29138593/intrathecal-pain-management-a-team-based-approach
#5
REVIEW
Jeremy A Adler, Neona M Lotz
Objective: Physician assistants (PAs), nurse practitioners (NPs), and registered nurses (RNs) provide professional services on pain management teams. This review provides an overview of the practical management of chronic pain with intrathecal (IT) therapy using an interprofessional approach (eg, physicians and other health care professionals), with a focus on the contributions of PAs, NPs, and RNs. Methods: Narrative review based on literature searches of the Medline database and treatment guidelines on the use of IT therapy in the management of patients with chronic pain...
2017: Journal of Pain Research
https://www.readbyqxmd.com/read/29136115/estradiol-levels-are-altered-in-human-immunodeficiency-virus-infected-pregnant-women-randomized-to-efavirenz-versus-lopinavir-ritonavir-based-antiretroviral-therapy
#6
Chloe R McDonald, Andrea L Conroy, Joel L Gamble, Eszter Papp, Michael Hawkes, Peter Olwoch, Paul Natureeba, Moses Kamya, Michael Silverman, Deborah Cohan, Catherine A Koss, Grant Dorsey, Kevin C Kain, Lena Serghides
Background: Combination antiretroviral therapy (cART) use in pregnancy has been associated with hormonal dysregulation. We performed a secondary retrospective analysis of longitudinal progesterone and estradiol levels in pregnancy using specimens from the Protease Inhibitors to Reduce Malaria Morbidity in HIV-infected Pregnant Women study, which randomized Ugandan human immunodeficiency virus (HIV)-infected ART-naive women to initiate either lopinavir/ritonavir (LPV/r)-based or efavirenz (EFV)-based cART...
November 10, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/29135752/experiences-and-shared-meaning-of-teamwork-and-interprofessional-collaboration-among-health-care-professionals-in-primary-health-care-settings-a-systematic-review
#7
Carine Sangaleti, Mariana Cabral Schveitzer, Marina Peduzzi, Elma Lourdes Campos Pavone Zoboli, Cassia Baldini Soares
BACKGROUND: During the last decade, teamwork has been addressed under the rationale of interprofessional practice or collaboration, highlighted by the attributes of this practice such as: interdependence of professional actions, focus on user needs, negotiation between professionals, shared decision making, mutual respect and trust among professionals, and acknowledgment of the role and work of the different professional groups. Teamwork and interprofessional collaboration have been pointed out as astrategy for effective organization of health care services as the complexity of healthcare requires integration of knowledge and practices from differente professional groups...
November 2017: JBI Database of Systematic Reviews and Implementation Reports
https://www.readbyqxmd.com/read/29134981/biochemical-hormonal-and-histological-changes-in-prostate-of-wistar-rats-following-long-term-streptozotocin-induced-diabetes-mellitus
#8
Bosede Popoola, Olivia Ashefor, Olubukola Akanni, Oluwatosin Adaramoye
Diabetes mellitus (DM) is characterized by hyperglycemia and endocrine disorder. Diabetes mellitus is knownto promote male infertility by affecting sperm quality through altered steroidogenesis. The role of prostatic fluid in maintenance of sperm quality have been established. However, the effect of DM on prostate health is poorly understood.This study was designed to investigate the biochemical, hormonal and histological changes in prostate of male Wistar ratsafter 3- and 5-months DM. Twenty-six adult male Wistar rats were assigned into three groups...
June 30, 2017: Nigerian Journal of Physiological Sciences: Official Publication of the Physiological Society of Nigeria
https://www.readbyqxmd.com/read/29134506/the-risk-of-eating-disorders-and-bone-health-in-young-adults-the-mediating-role-of-body-composition-and-fitness
#9
Miriam Garrido-Miguel, Ana Torres-Costoso, María Martínez-Andrés, Blanca Notario-Pacheco, Ana Díez-Fernández, Celia Álvarez-Bueno, Jorge Cañete García-Prieto, Vicente Martínez-Vizcaíno
PURPOSE: To analyze the independent relationship between the risk of eating disorders and bone health and to examine whether this relationship is mediated by body composition and cardiorespiratory fitness (CRF). METHODS: In this cross-sectional study, bone-related variables, lean mass, fat mass (by DXA), risk of eating disorders (SCOFF questionnaire), height, weight, waist circumference and CRF were measured in 487 university students aged 18-30 years from the University of Castilla-La Mancha, Spain...
November 13, 2017: Eating and Weight Disorders: EWD
https://www.readbyqxmd.com/read/29133283/open-source-electronic-health-record-systems-for-low-resource-settings-systematic-review
#10
REVIEW
Assel Syzdykova, André Malta, Maria Zolfo, Ermias Diro, José Luis Oliveira
BACKGROUND: Despite the great impact of information and communication technologies on clinical practice and on the quality of health services, this trend has been almost exclusive to developed countries, whereas countries with poor resources suffer from many economic and social issues that have hindered the real benefits of electronic health (eHealth) tools. As a component of eHealth systems, electronic health records (EHRs) play a fundamental role in patient management and effective medical care services...
November 13, 2017: JMIR Medical Informatics
https://www.readbyqxmd.com/read/29132847/a-scoping-review-on-interventions-to-promote-physical-activity-among-adults-with-disabilities
#11
REVIEW
Oscar Castro, Kwok Ng, Elizaveta Novoradovskaya, Grégoire Bosselut, Mary Hassandra
BACKGROUND: Despite the strong evidence that physical activity (PA) is a key determinant of health, there is limited knowledge on the content and outcomes of PA promotion interventions among individuals with disabilities. OBJECTIVE: To conduct a scoping review in order to examine the published literature on PA promotion interventions among adults with disabilities. METHODS: A scoping review following the methodological framework provided by Arksey and O'Malley used electronic databases (MEDLINE, PsycINFO, and CINAHL), reference lists, and journals to locate studies...
October 31, 2017: Disability and Health Journal
https://www.readbyqxmd.com/read/29132318/bugmat-and-findneighbour-command-line-and-server-applications-for-investigating-bacterial-relatedness
#12
Oriol Mazariegos-Canellas, Trien Do, Tim Peto, David W Eyre, Anthony Underwood, Derrick Crook, David H Wyllie
BACKGROUND: Large scale bacterial sequencing has made the determination of genetic relationships within large sequence collections of bacterial genomes derived from the same microbial species an increasingly common task. Solutions to the problem have application to public health (for example, in the detection of possible disease transmission), and as part of divide-and-conquer strategies selecting groups of similar isolates for computationally intensive methods of phylogenetic inference using (for example) maximal likelihood methods...
November 13, 2017: BMC Bioinformatics
https://www.readbyqxmd.com/read/29131132/points-of-concern-in-post-acute-kidney-injury-management
#13
Jill Vanmassenhove, Raymond Vanholder, Norbert Lameire
The incidence of acute kidney injury (AKI) will in the future remain high, partly due to an increase in comorbidities and other AKI favoring factors such as the rise in high-risk diagnostic and therapeutic interventions. AKI has emerged as a major public health concern with high human and financial costs. It has recently been demonstrated that patients surviving an AKI episode show increased all-cause mortality, chronic kidney disease (CKD), ESRD, cardiovascular events, and reduced quality of life. Although it is important to acknowledge that, after an AKI episode, the risk of dying by far exceeds the risk of developing incident or progressive CKD and/or entering a maintenance renal replacement therapy (RRT) program, currently only a minority of patients are referred for renal follow-up, even after AKI-requiring RRT...
November 2, 2017: Nephron
https://www.readbyqxmd.com/read/29130068/diet-and-physical-activity-behaviors-in-primary-care-patients-with-recent-intentional-weight-loss
#14
Bethany Barone Gibbs, Dana Tudorascu, Cindy L Bryce, Diane Comer, Gary S Fischer, Rachel Hess, Kimberly A Huber, Kathleen M McTigue, Laurey R Simkin-Silverman, Molly B Conroy
Purpose: Lifestyle habits of primary care patients with recent, intentional weight loss are unclear and need to be better understood to aid in translational health promotion efforts. We aimed to characterize diet and exercise habits in primary care patients with recent, intentional weight loss, comparing those with greater (≥10%) vs. lesser (5 to <10%) weight loss. Methods: This was a cross-sectional analysis of baseline data from a randomized trial comparing weight loss maintenance interventions...
2017: Translational Journal of the American College of Sports Medicine
https://www.readbyqxmd.com/read/29129410/iron-metabolism-and-the-role-of-the-iron-regulating-hormone-hepcidin-in-health-and-disease
#15
Raed Daher, Hana Manceau, Zoubida Karim
Although iron is vital, its free form is likely to be involved in oxidation-reduction reactions, leading to the formation of free radicals and oxidative stress. Living organisms have developed protein systems to transport free iron through the cell membranes and biological fluids and store it in a non-toxic and readily mobilizable form to avoid iron toxicity. Hepcidin plays a crucial role in maintaining iron homeostasis. Hepcidin expression is directly regulated by variations in iron intake and its repression leads to an increase in bioavailable serum iron level...
November 9, 2017: La Presse Médicale
https://www.readbyqxmd.com/read/29129048/-guida-per-la-determinazione-del-sangue-occulto-fecale-metodo-immunochimico-quantitativo-fit-hb-nei-programmi-di-screening-per-il-carcinoma-colorettale
#16
Tiziana Rubeca, Stefano Rapi, Silvia Deandrea, Morena Malaspina, Basilio Ubaldo Passamonti, Elena Grassi, Anna Maria Cioccarelli, Enrico Marchetti, Michela Boni, Filippo Cellai, Marco Pradella, Franco Gattafoni, Sabrina Rotolo
BACKGROUND: in Italy, colorectal cancer screening is included as part of the Italian National Health Service - SSN (Servizio Sanitario Nazionale) Essential Levels of Care - LEA (Livelli Essenziali Assistenziali) and the European Guidelines, which specify quantitative FIT-Hb testing as the best strategy for organised screening programmes. To ensure consistent operating standards in Member States, European regulations require the implementation of certification and accreditation requirements for diagnostic and care-related processes...
September 2017: Epidemiologia e Prevenzione
https://www.readbyqxmd.com/read/29128516/west-nile-virus-anopheles-flavivirus-a-novel-flavivirus-as-well-as-merida-like-rhabdovirus-turkey-in-field-collected-mosquitoes-from-thrace-and-anatolia
#17
Ceren Öncü, Annika Brinkmann, Filiz Günay, Sırrı Kar, Kerem Öter, Yasemen Sarıkaya, Andreas Nitsche, Yvonne-Marie Linton, Bülent Alten, Koray Ergünay
Mosquitoes are involved in the transmission and maintenance of several viral diseases with significant health impact. Biosurveillance efforts have also revealed insect-specific viruses, observed to cocirculate with pathogenic strains. This report describes the findings of flavivirus and rhabdovirus screening, performed in eastern Thrace and Aegean region of Anatolia during 2016, including and expanding on locations with previously-documented virus activity. A mosquito cohort of 1545 individuals comprising 14 species were collected and screened in 108 pools via generic and specific amplification and direct metagenomics by next generation sequencing...
November 8, 2017: Infection, Genetics and Evolution
https://www.readbyqxmd.com/read/29128413/association-of-citizenship-status-with-kidney-transplantation-in-medicaid-patients
#18
Jenny I Shen, Daniel Hercz, Lilly M Barba, Holly Wilhalme, Erik L Lum, Edmund Huang, Uttam Reddy, Leslie Salas, Sitaram Vangala, Keith C Norris
BACKGROUND: Although individuals classified as nonresident aliens, including undocumented immigrants, are entitled to receive emergency dialysis in the United States regardless of their ability to pay, most states do not provide them with subsidized care for maintenance dialysis or kidney transplantation. We explored whether nonresident aliens have similar outcomes to US citizens after receiving kidney transplants covered by Medicaid, a joint federal and state health insurance program...
November 8, 2017: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/29128011/overview-of-hematopoietic-cell-transplantation-for-the-treatment-of-hematologic-malignancies
#19
REVIEW
Nathan Singh, Alison W Loren
Allogeneic hematopoietic cell transplantation offers the best chance for cure in many hematologic malignancies. Key decisions include patient selection, donor and graft source, conditioning regimen, and graft-versus-host disease (GVHD) prophylaxis. Transplant is risky; only one-third survive long term. Complications include relapse, GVHD, infection, and end-organ dysfunction. Expanding indications for transplantation, advancing upper age limits, and improvements in patient care have resulted in increasing numbers of transplant survivors...
December 2017: Clinics in Chest Medicine
https://www.readbyqxmd.com/read/29127911/healthy-minds-from-0-100-years-optimising-the-use-of-european-brain-imaging-cohorts-lifebrain
#20
K B Walhovd, A M Fjell, R Westerhausen, L Nyberg, K P Ebmeier, U Lindenberger, D Bartrés-Faz, W F C Baaré, H R Siebner, R Henson, C A Drevon, G P Knudsen, I Budin-Ljøsne, B W J H Penninx, P Ghisletta, O Rogeberg, L Tyler, L Bertram
The main objective of "Lifebrain" is to identify the determinants of brain, cognitive and mental (BCM) health at different stages of life. By integrating, harmonising and enriching major European neuroimaging studies across the life span, we will merge fine-grained BCM health measures of more than 5,000 individuals. Longitudinal brain imaging, genetic and health data are available for a major part, as well as cognitive and mental health measures for the broader cohorts, exceeding 27,000 examinations in total...
November 8, 2017: European Psychiatry: the Journal of the Association of European Psychiatrists
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