Mohammad Soleimani, Seyed Mahbod Baharnoori, Kasra Cheraqpour, Bita Momenaei, Reza Mirshahi, Collin Chow, Sumaiya Shahjahan, Tara Nguyen, Mohammad Javad Ashraf, Xiaoke Huang, Raghuram Koganti, Makan Cheraghpour, Mahmood Ghassemi, Ali R Djalilian
Mustard agents are vesicants that were used in warfare multiple times. They are potent alkylating agents that activate cellular pathways of apoptosis, increase oxidative stress, and induce inflammation. Eyes are particularly susceptible to mustard exposure with a wide range of ocular surface damage. Three main categories of mustard-related eye injuries are acute, chronic, and delayed-onset manifestations. Mustard keratopathy (MK) is a known complication characterized by corneal opacification, ulceration, thinning, and neovascularization that can lead to severe vision loss and discomfort...
July 3, 2023: Experimental Eye Research