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https://www.readbyqxmd.com/read/28074019/point-organ-radiation-dose-in-abdominal-ct-effect-of-patient-off-centering-in-an-experimental-human-cadaver-study
#1
Ranish Deedar Ali Khawaja, Sarabjeet Singh, Atul Padole, Alexi Otrakji, Diego Lira, Da Zhang, Bob Liu, Andrew Primak, George Xu, Mannudeep K Kalra
To determine the effect of patient off-centering on point organ radiation dose measurements in a human cadaver scanned with routine abdominal CT protocol. A human cadaver (88 years, body-mass-index 20 kg/m(2)) was scanned with routine abdominal CT protocol on 128-slice dual source MDCT (Definition Flash, Siemens). A total of 18 scans were performed using two scan protocols (a) 120 kV-200 mAs fixed-mA (CTDIvol 14 mGy) (b) 120 kV-125 ref mAs (7 mGy) with automatic exposure control (AEC, CareDose 4D) at three different positions (a) gantry isocenter, (b) upward off-centering and (c) downward off-centering...
January 10, 2017: Radiation Protection Dosimetry
https://www.readbyqxmd.com/read/28070266/serum-and-cerebrospinal-fluid-immune-mediators-in-children-with-autistic-disorder-a-longitudinal-study
#2
Carlos A Pardo, Cristan A Farmer, Audrey Thurm, Fatma M Shebl, Jorjetta Ilieva, Simran Kalra, Susan Swedo
BACKGROUND: The causes of autism likely involve genetic and environmental factors that influence neurobiological changes and the neurological and behavioral features of the disorder. Immune factors and inflammation are hypothesized pathogenic influences, but have not been examined longitudinally. METHODS: In a cohort of 104 participants with autism, we performed an assessment of immune mediators such as cytokines, chemokines, or growth factors in serum and cerebrospinal fluid (n = 67) to determine potential influences of such mediators in autism...
2017: Molecular Autism
https://www.readbyqxmd.com/read/28066594/cough-frequency-monitors-can-they-discriminate-patient-from-environmental-coughs
#3
Stefan T Kulnik, Natalie M Williams, Lalit Kalra, John Moxham, Surinder S Birring
BACKGROUND: Objective cough frequency measurements are increasingly applied in clinical research. Technological advances enable automated detection and counting of cough events from sound recordings of many hours' duration. A possible limitation of sound-based cough frequency measurement is the contamination of recordings by environmental coughs (coughs from persons other than the patient). This study aimed to investigate the accuracy of a sound-based cough monitor for detecting and discriminating patient cough from environmental cough...
November 2016: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28065976/refractory-diabetes-focus-on-the-obvious
#4
Sanjay Kalra, Vipin Talwar
Refractory diabetes, characterized by poor glycaemic control despite adequate treatment, is an important entity. In this condition, even the best therapeutic regimes tailored for rapid symptomatic relief and attainment of glycaemic goals may not work. The need is to revive the clinical angle of endocrinology, including a detailed history, thorough examination, judicious use of investigations and patient specific management plan, along with quality control by self and peer assessment.
January 2017: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/28065975/vulvovaginitis-and-diabetes
#5
Bharti Kalra, Sanjay Kalra
Vulvovaginitis is a commonly encountered comorbid condition of diabetes, and is linked to poor glycaemic control. Proper, timely diagnosis and management is necessary to ensure optimal perineal/genital and metabolic health. Knowledge of current guidelines and recommendations helps in achieving this goal. This review describes the etiology, pathogenesis, clinical features, differential diagnosis, management and prevention of VV in diabetes.
January 2017: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/28063802/resolving-the-kga1c-paradox-in-the-management-of-type-2-diabetes-mellitus
#6
REVIEW
Jaime Davidson, Sanjay Kalra, Vikram Singh, Mayuresh Fegade, Gursimran Singh, Amey Mane
Excess body weight is a leading cause of metabolic complications such as hypertension and dyslipidemia in T2DM patients. Available antihyperglycemic agents have minimal or no impact on these complications and a majority are known to trigger weight gain, thereby exerting a paradoxical effect on overall metabolic status. This review introduces the concept of 'KgA1c paradox' and underscores the significance of resolving this paradox for comprehensive T2DM management. It provides a therapeutic rationale for inclusion of sodium glucose cotransporter 2 inhibitors in the T2DM treatment algorithm as these agents have demonstrated favorable glycemic effects along with reduction in body weight...
December 13, 2016: Diabetes & Metabolic Syndrome
https://www.readbyqxmd.com/read/28055250/assessment-of-chest-ct-at-ctdivol-less-than-1-mgy-with-iterative-reconstruction-techniques
#7
Atul Padole, Subba Digumarthy, Efren Flores, Rachna Madan, Shelly Mishra, Amita Sharma, Mannudeep K Kalra
OBJECTIVES: To assess the image quality of chest CT reconstructed with image-based (SafeCT), adaptive statistical (ASIR), and model based (MBIR) iterative reconstruction techniques (IRTs) at CTDIvol less than 1 mGy. METHODS: In an IRB approved study, 25 patients gave written informed consent for acquisition of three Reduced Dose (RD) (0.25, 0.4, 0.8 mGy) chest CT after standard of care CT (8 mGy) on a 64-channel multi-detector CT (MDCT) and reconstructed with SafeCT, ASIR, and MBIR...
January 5, 2017: British Journal of Radiology
https://www.readbyqxmd.com/read/28042408/an-unusual-cause-of-postabortal-fever-requiring-prompt-surgical-intervention-a-pyomyoma-and-its-imaging-features
#8
Rashmi Bagga, Rakhi Rai, Jasvinder Kalra, Pradip K Saha, Tulika Singh
Pyomyoma is an unusual complication of leiomyoma, occurring most commonly in the postpartum, postabortal, and post-menopausal periods. It develops due to infection in necrotic foci within leiomyoma, which is more common during pregnancy due to rapid growth, and in postmenopausal women due to vascular insufficiency. Other contributing factors are curettage, gynecological surgery, cervical stenosis, immunodeficiency, and recently, uterine artery embolization. It presents with a typical triad of sepsis, leiomyoma, and absence of any apparent source of infection...
January 2017: Oman Medical Journal
https://www.readbyqxmd.com/read/28039220/the-british-junior-cardiologists-association
#9
Afzal Sohaib, Paul Kalra
No abstract text is available yet for this article.
December 7, 2016: European Heart Journal
https://www.readbyqxmd.com/read/28038717/american-college-of-cardiology-acc-s-pinnacle-india-quality-improvement-program-piqip-inception-progress-and-future-direction-a-report-from-the-piqip-investigators
#10
Ankur Kalra, Nathan Glusenkamp, Karen Anderson, Ram N Kalra, Prafulla G Kerkar, Ganesh Kumar, Thomas M Maddox, William J Oetgen, Salim S Virani
Cardiovascular diseases have surpassed infectious disorders to become the leading cause of morbidity and mortality in India.(1) A national-level registry comprehensively documenting the current-day prevalence of cardiovascular risk factors and disease burden among patients seeking care in the outpatient setting in India is currently non-existent. With a burgeoning urban population, the cardiovascular disease burden in India is set to skyrocket, with an estimated 18 million productive years of life lost by 2030...
December 2016: Indian Heart Journal
https://www.readbyqxmd.com/read/28034585/maximal-aortic-diameter-affects-outcome-after-endovascular-repair-of-abdominal-aortic-aneurysms
#11
Ying Huang, Peter Gloviczki, Audra A Duncan, Manju Kalra, Gustavo S Oderich, Mark D Fleming, William S Harmsen, Thomas C Bower
OBJECTIVE: The purpose of this study was to evaluate whether maximal aortic diameter affects outcome after endovascular aneurysm repair (EVAR) of abdominal aortic aneurysm (AAA). METHODS: Clinical data of patients undergoing EVAR between 1997 and 2011 for nonruptured asymptomatic AAAs in a tertiary center were reviewed. Patients were classified according to diameter of AAA: group 1, <5.0 cm; group 2, 5.0 to 5.4 cm; group 3, 5.5 to 5.9 cm; and group 4, ≥6...
December 26, 2016: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/28031611/poetry-in-teaching-pharmacology-exploring-the-possibilities
#12
Juhi Kalra, Satendra Singh, Dinesh Badyal, Purnima Barua, Taruna Sharma, Dinesh Chandra Dhasmana, Tejinder Singh
OBJECTIVES: To explore poetry as a tool for active learning in linking knowledge and affective domains and to find if correlating learning with imagination can be used in "assessment for learning." MATERIALS AND METHODS: After taking a conventional lecture on Asthma, a creative writing assignment in the form of poetry writing was given to the students. Different triggers were given to the students to channelize their thought pattern in a given direction that was linked to specific areas of academic relevance...
October 2016: Indian Journal of Pharmacology
https://www.readbyqxmd.com/read/28031609/introducing-structured-viva-voce-examination-in-medical-undergraduate-pharmacology-a-pilot-study
#13
D C Dhasmana, Suman Bala, Rajendra Sharma, Taruna Sharma, Saurabh Kohli, Neeraj Aggarwal, Juhi Kalra
OBJECTIVE: Viva voce examination is an important tool of evaluation in medical examinations marred by high subjectivity. Gross subjectivity in viva voce assessment can be reduced by structuring it. MATERIALS AND METHODS: The marks obtained in theory and viva voce (traditional viva voce examination [TVVE]) of I sessional, II MBBS students were compared and a huge disparity was identified. A structured viva voce examination (SVVE) was then proposed and experimented as an objective and standardized alternative...
October 2016: Indian Journal of Pharmacology
https://www.readbyqxmd.com/read/28031606/role-of-concept-map-in-teaching-general-awareness-and-pharmacotherapy-of-hiv-aids-among-second-professional-medical-students
#14
Suman Bala, D C Dhasmana, Juhi Kalra, Saurabh Kohli, Taruna Sharma
OBJECTIVE: Medical students as future doctors will play an important role in caring for HIV-infected patients. This study assessed and evaluated the existing level of knowledge of MBBS students about HIV/AIDS given through lecture delivery methods and by use of concept map (CM). MATERIALS AND METHODS: This study was carried out on 150 professional MBBS students of tertiary care hospital. A pretest was conducted by giving 10 multiple choice questions (MCQ) of general awareness and 15 questions regarding pharmacotherapy of HIV/AIDS...
October 2016: Indian Journal of Pharmacology
https://www.readbyqxmd.com/read/28030655/percutaneous-coronary-intervention-with-bioresorbable-scaffolds-in-a-young-child
#15
Tamim M Nazif, Sanjog Kalra, Ziad A Ali, Dimitrios Karmpaliotis, Mariel E Turner, Thomas J Starc, Yang Cao, Charles C Marboe, Michael B Collins, Martin B Leon, Ajay J Kirtane
Importance: Although much less frequent than in adults, coronary artery disease requiring revascularization may develop in children because of homozygous familial hypercholesterolemia or other underlying conditions. Percutaneous coronary intervention (PCI) with a bioresorbable scaffold (BRS) may have advantages over metallic coronary stents in this population. Objective: To present a case of the successful treatment of unstable, multivessel coronary artery disease in a child with PCI with BRS implantation...
December 28, 2016: JAMA Cardiology
https://www.readbyqxmd.com/read/28028344/colloid-goiter-in-ectopic-thyroid-tissue-presenting-as-submandibular-swelling-with-a-coexisting-functional-orthotopic-thyroid-gland-in-a-pregnant-female
#16
Renuka Verma, Sumiti Gupta, Rajnish Kalra, Rajeev Sen, Swagatika Samal, Jyoti Sharma, Shivani Malik
No abstract text is available yet for this article.
October 2016: Journal of Cytology
https://www.readbyqxmd.com/read/28024764/precision-of-manual-landmark-identification-between-as-received-and-oriented-volume-rendered-cone-beam-computed-tomography-images
#17
Abhishek Gupta, Om Prakash Kharbanda, Rajiv Balachandran, Viren Sardana, Shilpa Kalra, Sushma Chaurasia, Harish Kumar Sardana
INTRODUCTION: The objective of this study was to evaluate the effect of the orientation of cone-beam computed tomography (CBCT) images on the precision and reliability of 3-dimensional cephalometric landmark identification. METHODS: Ten CBCT scans were used for manual landmark identification. Volume-rendered images were oriented by aligning the Frankfort horizontal and transorbital planes horizontally, and the midsagittal plane vertically. A total of 20 CBCT images (10 as-received and 10 oriented) were anonymized, and 3 random sets were generated for manual landmark plotting by 3 expert orthodontists...
January 2017: American Journal of Orthodontics and Dentofacial Orthopedics
https://www.readbyqxmd.com/read/28024295/characterization-of-two-novel-fancg-mutations-in-indian-fanconi-anemia-patients
#18
Avani Solanki, C Kumar Selvaa, Frenny Sheth, Nita Radhakrishnan, Manas Kalra, Babu Rao Vundinti
FA is a rare recessive genetic disorder with autosomal or X-linked mode of inheritance and is associated with 19 different FA complementation groups. We have studied three patients clinically diagnosed as FA. All three patients showed a high frequency chromosomal breakage in MMC induced blood cultures and FANCD2 non-monoubiquitination by western blotting. The molecular analysis using direct sequencing revealed two novel mutations in FANCG; 2 novel mutations c.1143+5G>C and c.883dupG, and a reported mutation c...
November 29, 2016: Leukemia Research
https://www.readbyqxmd.com/read/28010911/variations-in-magnetic-resonance-imaging-provision-and-processes-among-canadian-academic-centres
#19
Sonia Vanderby, Andreea Badea, Juan Nicolás Peña Sánchez, Neil Kalra, Paul Babyn
PURPOSE: Increasing demand has led to questions regarding the appropriateness of advanced imaging exams, particularly for magnetic resonance imaging (MRI). The study aimed to explore variability in MRI service provision and request variation within Canadian academic medical imaging departments, particularly factors potentially affecting appropriate MRI service provision. METHODS: All Canadian academic centres with medical imaging residency programs were invited to participate...
December 20, 2016: Canadian Association of Radiologists Journal, Journal L'Association Canadienne des Radiologistes
https://www.readbyqxmd.com/read/28006875/neutrophil-to-lymphocyte-ratio-correlates-with-proinflammatory-neutrophils-and-predicts-death-in-low-meld-cirrhotic-patients
#20
Avash Kalra, Joel P Wedd, Kiran M Bambha, Jane Gralla, Lucy Golden-Mason, Christine Collins, Hugo R Rosen, Scott W Biggins
The Model for End Stage Liver Disease (MELD)has reduced accuracy for liver transplant (LT) waitlist mortalitywhen MELD ≤20. Neutrophil to Lymphocyte Ratio (NLR) is a biomarker associated with systemic inflammation and may predict cirrhotic decompensation and death. We aimedto evaluate the prognostic utility of high NLR (≥4) for liver-related death among low MELD patients listed for LT, controlling for stage of cirrhosis.In a nested case-control study ofcirrhotic adults awaiting LT (2/2002-5/2011), Cases were LT candidates with aliver-related death and MELD≤20 within 90 days of death...
December 22, 2016: Liver Transplantation
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