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https://www.readbyqxmd.com/read/28304008/contraception-in-women-with-diabetes
#1
Bharti Kalra, Sanjay Kalra
This brief article covers the diabetes related aspects of contraception in women. It classifies various methods of contraception and describes how presence of diabetes influences their use. The article lists the high risk conditions in diabetes which may discourage use of combined hormonal contraceptives. It discusses the relation of glycaemic control and medical termination of pregnancy (MTP), and calls for universal provision of contraceptive services to all women with diabetes.
March 2017: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/28302426/proximity-of-lateral-critical-structures-to-the-all-epiphyseal-outside-in-femoral-tunnels-in-pediatric-anterior-cruciate-ligament-reconstruction
#2
Mark K Lane, Jennifer Mutch, Kaitlyn Ratkowiak, Stephen E Lemos, Kunal Kalra
PURPOSE: To describe the proximity of the lateral critical structures (peroneal nerve [PN], popliteus tendon [PT], lateral collateral ligament [LCL], and articular cartilage [AC]) to the femoral tunnel for outside-in all-epiphyseal anterior cruciate ligament (ACL) reconstruction in reference to knee flexion angle. METHODS: All-epiphyseal ACL reconstructions were performed in 12 human cadaveric knees using arthroscopy and outside-in drilling for anatomic femoral tunnel placement that was ensured by identifying the center of the total ACL footprint...
March 13, 2017: Arthroscopy: the Journal of Arthroscopic & related Surgery
https://www.readbyqxmd.com/read/28296198/mechanical-and-microstructural-analysis-of-a-radially-expandable-vascular-conduit-for-neonatal-and-pediatric-cardiovascular-surgery
#3
Abigail E Loneker, Samuel K Luketich, Doug Bernstein, Arush Kalra, Alan W Nugent, Antonio D'Amore, Denver M Faulk
In pediatric cardiovascular surgery, there is a significant need for vascular prostheses that have the potential to grow with the patient following implantation. Current clinical options consist of nonexpanding conduits, requiring repeat surgeries as the patient outgrows the device. To address this issue, PECA Labs has developed a novel ePTFE vascular conduit with the capability of being radially expanded via balloon catheterization. In the described study, a systematic characterization and comparison of two proprietary ePTFE expandable conduits was conducted...
March 10, 2017: Journal of Biomedical Materials Research. Part B, Applied Biomaterials
https://www.readbyqxmd.com/read/28295412/machine-learning-will-transform-radiology-significantly-within-the-next-five-years
#4
Ge Wang, Mannudeep Kalra, Colin G Orton
With impressive progress in machine learning, there has been increasingly more interest in its relevance to medical physics, which involves both medical imaging and radiation treatment planning. However, because it is still generally unclear how to identify unique niches, utilize big data, and optimize neural networks for machine learning, machine learning is yet to have a major impact on medical physics practice. Nevertheless, there are optimistic opinions that machine learning will have a major impact on medical physics and radiology within the next five years...
March 11, 2017: Medical Physics
https://www.readbyqxmd.com/read/28289893/indian-injection-technique-study-population-characteristics-and-injection-practices
#5
Sanjay Kalra, Ambrish Mithal, Rakesh Sahay, Mathew John, A G Unnikrishnan, Banshi Saboo, Sujoy Ghosh, Debmalya Sanyal, Laurence J Hirsch, Vandita Gupta, Kenneth W Strauss
INTRODUCTION: It was estimated that 3.2 million Indians with diabetes injected insulin in 2010, but little is known about the techniques used. METHODS: In 2015 we conducted an injection technique questionnaire (ITQ) survey throughout India involving 1011 patients. Indian values were compared with those from 41 other countries participating in the ITQ, known here as rest of world (ROW). RESULTS: Mean HbA1c was 8.6. BMI values in India were 1...
March 13, 2017: Diabetes Therapy: Research, Treatment and Education of Diabetes and related Disorders
https://www.readbyqxmd.com/read/28289892/indian-injection-technique-study-injecting-complications-education-and-the-health-care-professional
#6
Sanjay Kalra, Ambrish Mithal, Rakesh Sahay, Mathew John, A G Unnikrishnan, Banshi Saboo, Sujoy Ghosh, Debmalya Sanyal, Laurence J Hirsch, Vandita Gupta, Kenneth W Strauss
INTRODUCTION: Using the Indian and rest of world (ROW) injection technique questionnaire (ITQ) data, we address key insulin injection complications. METHODS: In 2015 we conducted an ITQ survey throughout India involving 1011 patients. Indian values were compared with those from 41 other countries participating in the ITQ, known here as ROW. RESULTS: More than a quarter of Indian insulin users described lesions consistent with lipohypertrophy (LH) at their injection sites and approximately 1 in 5 were found to have LH by the examining nurse (using visual inspection and palpation)...
March 13, 2017: Diabetes Therapy: Research, Treatment and Education of Diabetes and related Disorders
https://www.readbyqxmd.com/read/28288259/travel-bans-and-threats-to-us-health-care-our-hearts-are-at-stake
#7
Ankur Kalra, Prediman K Shah, William A Zoghbi
No abstract text is available yet for this article.
March 13, 2017: JAMA Cardiology
https://www.readbyqxmd.com/read/28279291/clinical-benefit-of-ablating-localized-sources-for-human-atrial-fibrillation-the-indiana-university-firm-registry
#8
John M Miller, Vikas Kalra, Mithilesh K Das, Rahul Jain, Jason B Garlie, Jordan A Brewster, Gopi Dandamudi
BACKGROUND: Mounting evidence shows that localized sources maintain atrial fibrillation (AF). However, it is unclear in unselected "real-world" patients if sources drive persistent atrial fibrillation (PeAF), long-standing persistent atrial fibrillation (LPeAF), or paroxysmal atrial fibrillation (PAF); if right atrial sites are important; and what the long-term success of source ablation is. OBJECTIVES: The aim of this study was to analyze the role of rotors and focal sources in a large academic registry of consecutive patients undergoing source mapping for AF...
March 14, 2017: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/28275957/erratum-to-auxiliendo-primum-non-nocere-a-preliminary-view-of-the-devote-trial-comparing-cardiovascular-safety-of-insulin-degludec-versus-insulin-glargine-in-type-2-diabetes
#9
Sanjay Kalra
No abstract text is available yet for this article.
March 8, 2017: Diabetes Therapy: Research, Treatment and Education of Diabetes and related Disorders
https://www.readbyqxmd.com/read/28274080/aesthetic-retainer-cum-trainer
#10
Tulika Tripathi, Shilpa Kalra, Priyank Rai
Tongue thrust habit is one of the contributing factors in the relapse of orthodontic treatment results. Compliance with removable habit breaking appliance is a major issue to the dental practitioners treating patients of any age group. Through this case we introduce a more aesthetic and comfortable option to the patients requiring habit control for tongue thrusting and retention of treatment results. Hence, this appliance acts as a retainer cum trainer in such patients.
January 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28265344/association-of-nfkb1-gene-polymorphism-rs28362491-with-levels-of-inflammatory-biomarkers-and-susceptibility-to-diabetic-nephropathy-in-asian-indians
#11
Amar Gautam, Stuti Gupta, Mohit Mehndiratta, Mohini Sharma, Kalpana Singh, Om P Kalra, Sunil Agarwal, Jasvinder K Gambhir
AIM: To investigate the association of NFKB1 gene -94 ATTG insertion/deletion (rs28362491) polymorphism with inflammatory markers and risk of diabetic nephropathy in Asian Indians. METHODS: A total of 300 subjects were recruited (100 each), normoglycemic, (NG); type 2 diabetes mellitus (T2DM) without any complications (DM) and T2DM with diabetic nephropathy [DM-chronic renal disease (CRD)]. Analysis was carried out by polymerase chain reaction-restriction fragment length polymorphism and ELISA...
February 15, 2017: World Journal of Diabetes
https://www.readbyqxmd.com/read/28245209/ev-track-transparent-reporting-and-centralizing-knowledge-in-extracellular-vesicle-research
#12
Jan Van Deun, Pieter Mestdagh, Patrizia Agostinis, Özden Akay, Sushma Anand, Jasper Anckaert, Zoraida Andreu Martinez, Tine Baetens, Els Beghein, Laurence Bertier, Geert Berx, Janneke Boere, Stephanie Boukouris, Michel Bremer, Dominik Buschmann, James B Byrd, Clara Casert, Lesley Cheng, Anna Cmoch, Delphine Daveloose, Eva De Smedt, Seyma Demirsoy, Victoria Depoorter, Bert Dhondt, Tom A P Driedonks, Aleksandra Dudek, Abdou Elsharawy, Ilaria Floris, Andrew D Foers, Kathrin Gärtner, Abhishek D Garg, Edward Geeurickx, Jan Gettemans, Farzaneh Ghazavi, Bernd Giebel, Tom Groot Kormelink, Grace Hancock, Hetty Helsmoortel, Andrew F Hill, Vincent Hyenne, Hina Kalra, David Kim, Joanna Kowal, Sandra Kraemer, Petra Leidinger, Carina Leonelli, Yaxuan Liang, Lien Lippens, Shu Liu, Alessandra Lo Cicero, Shaun Martin, Suresh Mathivanan, Prabhu Mathiyalagan, Támas Matusek, Gloria Milani, Marta Monguió-Tortajada, Liselot M Mus, Dillon C Muth, Andrea Németh, Esther N M Nolte-'t Hoen, Lorraine O'Driscoll, Roberta Palmulli, Michael W Pfaffl, Bjarke Primdal-Bengtson, Erminia Romano, Quentin Rousseau, Susmita Sahoo, Natalia Sampaio, Monisha Samuel, Benjamin Scicluna, Bieke Soen, Anneleen Steels, Johannes V Swinnen, Maarit Takatalo, Safia Thaminy, Clotilde Théry, Joeri Tulkens, Isabel Van Audenhove, Susanne van der Grein, Alan Van Goethem, Martijn J van Herwijnen, Guillaume Van Niel, Nadine Van Roy, Alexander R Van Vliet, Niels Vandamme, Suzanne Vanhauwaert, Glenn Vergauwen, Frederik Verweij, Annelynn Wallaert, Marca Wauben, Kenneth W Witwer, Marijke I Zonneveld, Olivier De Wever, Jo Vandesompele, An Hendrix
We argue that the field of extracellular vesicle (EV) biology needs more transparent reporting to facilitate interpretation and replication of experiments. To achieve this, we describe EV-TRACK, a crowdsourcing knowledgebase (http://evtrack.org) that centralizes EV biology and methodology with the goal of stimulating authors, reviewers, editors and funders to put experimental guidelines into practice.
February 28, 2017: Nature Methods
https://www.readbyqxmd.com/read/28240799/revascularization-of-atherosclerotic-renal-artery-stenosis-for-chronic-heart-failure-versus-acute-pulmonary-oedema
#13
Darren Green, James P Ritchie, Constantina Chrysochou, Philip A Kalra
AIM: To determine whether the apparent benefit of revascularization of renal artery stenosis for "flash" pulmonary oedema extends to heart failure patients without a history of prior acute pulmonary oedema. METHODS: A prospective study of patients with renal artery stenosis and heart failure at a single centre between 1(st) January 1995 and 31(st) December 2010. Patients were divided into those with and without previous acute pulmonary oedema / decompensation. Survival analysis compared revascularization versus medical therapy in each group using Cox regression adjusted for age, eGFR, blood pressure, and co-morbidities...
February 27, 2017: Nephrology
https://www.readbyqxmd.com/read/28237984/effect-of-a-quality-improvement-program-to-improve-guideline-adherence-and-attainment-of-clinical-standards-in-dialysis-care-report-of-outcomes-in-year-1
#14
Sajeda Youssouf, Azri Nache, Chandrakumaran Wijesekara, Rachel J Middleton, David Lewis, Aladdin E Shurrab, Edmond O'Riordan, Lesley P Lappin, Donal O'Donoghue, Philip A Kalra, Janet Hegarty
BACKGROUND: Best practice in dialysis is synthesised in clear international guidelines. However, a large gap remains between the international guidelines and the actual delivery of care. In this paper, we report outcomes for the first year of a multifaceted dialysis improvement programme in our network. METHODS: One year collaborative involving 3 haemodialysis units and a peritoneal dialysis (PD) programme involving 299 dialysis patients. Each unit addressed a different indicator (unit A - catheter-related bloodstream infection [CRBSI], unit B - pre-dialysis blood pressure [BP], unit C - dialysis dose, unit D - anaemia) with a shared aim to match the top 10% in the UK...
February 25, 2017: Nephron
https://www.readbyqxmd.com/read/28225478/selected-abstracts-from-recent-publications-in-cardiopulmonary-disease-prevention-and-rehabilitation
#15
Peter H Brubaker, Sanjay Kalra
No abstract text is available yet for this article.
March 2017: Journal of Cardiopulmonary Rehabilitation and Prevention
https://www.readbyqxmd.com/read/28221262/recent-advances-in-computed-tomographic-technology-cardiopulmonary-imaging-applications
#16
Azadeh Tabari, Roberto Lo Gullo, Venkatesh Murugan, Alexi Otrakji, Subba Digumarthy, Mannudeep Kalra
Cardiothoracic diseases result in substantial morbidity and mortality. Chest computed tomography (CT) has been an imaging modality of choice for assessing a host of chest diseases, and technologic advances have enabled the emergence of coronary CT angiography as a robust noninvasive test for cardiac imaging. Technologic developments in CT have also enabled the application of dual-energy CT scanning for assessing pulmonary vascular and neoplastic processes. Concerns over increasing radiation dose from CT scanning are being addressed with introduction of more dose-efficient wide-area detector arrays and iterative reconstruction techniques...
March 2017: Journal of Thoracic Imaging
https://www.readbyqxmd.com/read/28220461/new-generation-coronary-stents-current-data-and-future-directions
#17
REVIEW
Ankur Kalra, Hasan Rehman, Sahil Khera, Braghadheeswar Thyagarajan, Deepak L Bhatt, Neal S Kleiman, Robert W Yeh
PURPOSE OF REVIEW: Drug-eluting stents are the mainstay in the treatment of coronary artery disease using percutaneous coronary intervention. Innovations developed to overcome the limitations of prior generations of stents include biodegradable polymer stents, drug-eluting stents without a polymer, and bioabsorbable scaffolds. Our review briefly discusses the clinical profiles of first- and second-generation coronary stents, and provides an up-to-date overview of design, technology, and clinical safety and efficacy profiles of newer generation coronary stents discussing the relevant clinical trials in this rapidly evolving area of interventional cardiology...
March 2017: Current Atherosclerosis Reports
https://www.readbyqxmd.com/read/28217531/endocrinology-in-haryana-50-years-of-statehood-15-years-of-service
#18
Dheeraj Kapoor, Sunil Mishra, Rajat Gupta, Sameer Aggarwal, Rajneesh Mittal, Sanjay Kalra
No abstract text is available yet for this article.
January 2017: Indian Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28217527/vascular-legacy-hope-advances-to-empa-reg-and-leader-a-surprising-similarity
#19
Sanjay Kalra, Rakesh Sahay
Recently reported cardiovascular outcome studies on empagliflozin (EMPA-REG) and liraglutide (LEADER) have spurred interest in this field of diabetology. This commentary compares and contrasts these studies with two equally important outcome trials conducted using blood pressure lowering agents. A comparison with MICROHOPE (using ramipril) and ADVANCE (using perindopril + indapamide) blood pressure arms throws up interesting facts. The degree of blood pressure lowering, dissociation between cardiovascular and cerebrovascular benefits, and discordance between renal and retinal outcomes are surprisingly similar in these trials, conducted using disparate molecules...
January 2017: Indian Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28217526/the-rule-of-two-thirds-in-diabetes-epidemiology
#20
Sanjay Kalra, Banshi Saboo, Rakesh Sahay, Deepak Khandelwal, Vipin Talwar, A G Unnikrishnan
This communication hypothesises a rule of two thirds which seems to operate in Indian diabetes epidemiology. Two thirds of all persons with dysglycemia are prediabetic; two thirds of all persons with diabetes are diagnosed to have the condtion; and two thirds are diagnosed before the age of 50 years. Two thirds of people with diabetes have concomitant hypetension or dyslipidemia; two thirds do not get their HbA1c assessed; and two thirds of those who do, do not achiev target values. Yet, two thirds of people with diabetes report satisfactory psychosocial health and quality of life, and adherence to dietary therapy and medication...
January 2017: Indian Journal of Endocrinology and Metabolism
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