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ischemic acute intestinal

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https://www.readbyqxmd.com/read/27899069/gastric-dilatation-and-intestinal-obstruction-mimicking-acute-coronary-syndrome-with-dynamic-electrocardiographic-changes
#1
H M M T B Herath, Anne Thushara Matthias, B S D P Keragala, W A E Udeshika, Aruna Kulatunga
BACKGROUND: ST elevation myocardial infarction is a medical emergency and the electrocardiogram is a part of the mainstay in the initial diagnosis. A variety of non-cardiac conditions have been known to mimic the electrocardiographic changes seen in acute coronary syndrome. We present a patient presenting with acute partial intestinal obstruction causing gastric distension and intestinal dilatation who also had dynamic electrocardiographic changes, mimicking anterior ST elevation myocardial infarction...
November 29, 2016: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/27832292/takayasu-arteritis-ta-first-presenting-with-intestinal-ischemia-a-case-report-and-review-of-gastrointestinal-tract-involvement-ischemic-and-non-ischemic-associated-with-ta
#2
REVIEW
Durga Prasanna Misra, Nagarajan Krishnan, Debasis Gochhait, Dantis Emmanuel, Vir Singh Negi
Takayasu arteritis (TA) is a large vessel vasculitis involving the aorta and its major branches. Insidious inflammation usually results in gradual arterial narrowing; however, critical organ ischemia is rare. We describe a young male with TA who presented with acute mesenteric ischemia requiring intestinal resection, followed by critical limb ischemia. In our literature review, we identified intestinal gangrene as a rare manifestation of TA. However, intestinal ischemia as the first manifestation of TA has been scarcely reported in the literature...
November 10, 2016: Rheumatology International
https://www.readbyqxmd.com/read/27830008/molecular-mechanisms-underlying-application-of-serum-procalcitonin-and-stool-mir-637-in-prognosis-of-acute-ischemic-stroke
#3
You-Mei Li, Xue-Yuan Liu
We and others have reported that the serum procalcitonin (PCT) level has a demonstrative role in predicting the long-term mortality after acute ischemic stroke (AIS) in Chinese population. Nevertheless, the underlying mechanisms remain ill-defined. In the current study, we further detected a close association of stool microRNA-637 (miR-637) levels with the long-term mortality after AIS in Chinese population. Moreover, the serum PCT and stool miR-637 levels appeared to be inversely correlated. AIS patients with lower levels of stool miR-637 appeared to predict more severe mortality in the long-term...
2016: American Journal of Translational Research
https://www.readbyqxmd.com/read/27828601/remote-ischemic-preconditioning-and-tacrolimus-in-the-fetal-small-bowel-transplant-in-mice
#4
Ricardo José Morello, Marcia Kiyomi Koike, Marcos de Souza Abrahão, Karen Ruggeri Saad, Paulo Fernandes Saad, Edna Frasson de Souza Montero
PURPOSE: To evaluate the effect of remote ischemic preconditioning (IPC-R) in the fetal small bowel transplantation model. METHODS: Two groups were constituted: The Isogenic transplant (ISO, C57BL/6 mice, n=24) and the allogenic transplant (ALO, BALB/c mice, n=24). In each group, the animals were distributed with and without IPC-R. It was obtained the following subgroups: Tx, IPC-R, Fk, IPC-Fk, in both strains. Intestinal grafts were stained with hematoxylin and eosin and immunohistochemically...
October 2016: Acta Cirúrgica Brasileira
https://www.readbyqxmd.com/read/27798441/runner-s-diarrhea-what-is-it-what-causes-it-and-how-can-it-be-prevented
#5
Erick P de Oliveira
PURPOSE OF REVIEW: Runner's diarrhea is an acute exercise-induced diarrhea. Usually, this is not a pathological situation but it can affect performance. This review focuses on the discussion of the main causes of runner's diarrhea and nutritional recommendations to prevent it. RECENT FINDINGS: Although based on limited data, multiple transportable carbohydrate intake during exercise instead of glucose alone can be recommended for preventing the urge to defecate and (possibly) diarrhea...
October 27, 2016: Current Opinion in Gastroenterology
https://www.readbyqxmd.com/read/27681959/accuracy-of-the-serum-intestinal-fatty-acid-binding-protein-for-diagnosis-of-acute-intestinal-ischemia-a-meta-analysis
#6
Da-Li Sun, Yun-Yun Cen, Shu-Min Li, Wei-Ming Li, Qi-Ping Lu, Peng-Yuan Xu
Numerous studies have investigated the utility of serum intestinal fatty-acid binding protein (I-FABP) in differentiating acute intestinal ischemia from acute abdomen. However, the results remain controversial. The aim of this meta-analysis is to determine the overall accuracy of serum I-FABP in the diagnosis of acute intestinal ischemia. Publications addressing the accuracy of serum I-FABP in the diagnosis of ischemic bowel diseases were selected from databases. The values of true-positive (TP), true-negative (TN), false-positive (FP), and false-negative (FN) were extracted or calculated for each study...
September 29, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27643963/death-from-barotrauma-due-to-compressed-air-a-medico-legal-analysis
#7
Pasquale Giugliano, Francesco Massoni, Antonello Crisci, Serafino Ricci
Lesions of the digestive tract due to barotrauma resulting from compressed air application are not common, are rarely lethal, and largely affect the sigmoid and descending colon. Moreover, their pathogenic mechanism is a topic of discussion because these lesions have multiple characteristics. Here, the authors describe an autoptic case of death from lesions of the ascending and transverse segments, with perforations and bleeding suffusions as well as ischemic areas covered the colonic wall that was extremely thinned, congested, and hemorrhagic, with considerable flattening leading to disappearance of the mucosal folds and with numerous petechial hemorrhages...
November 2016: Journal of Forensic Sciences
https://www.readbyqxmd.com/read/27642112/temporal-trends-predictors-and-outcomes-of-in-hospital-gastrointestinal-bleeding-associated-with-percutaneous-coronary-intervention
#8
Nileshkumar J Patel, Dhaval Pau, Nikhil Nalluri, Parth Bhatt, Badal Thakkar, Ritesh Kanotra, Kanishk Agnihotri, Nitesh Ainani, Nilay Patel, Nish Patel, Sapna Shah, Sabeeda Kadavath, Shilpkumar Arora, Azfar Sheikh, Apurva O Badheka, James Lafferty, Carlos Alfonso, Mauricio Cohen
Since the introduction of new antiplatelet and anticoagulant agents in the last decade, large-scale data studying gastrointestinal bleeding (GIB) in patients undergoing percutaneous coronary intervention (PCI) are lacking. Using the Nationwide Inpatient Sample, we identified all hospitalizations from 2006 to 2012 that required PCI. Temporal trends in the incidence and multivariate predictors of GIB associated with PCI were analyzed. A total of 4,376,950 patients underwent PCI in the United States during the study period...
October 15, 2016: American Journal of Cardiology
https://www.readbyqxmd.com/read/27573037/severity-of-pancreatitis%C3%A2-associated-intestinal-mucosal-barrier-injury-is-reduced-following-treatment-with-the-nadph-oxidase-inhibitor-apocynin
#9
Wenhong Deng, Ablikim Abliz, Sheng Xu, Rongze Sun, Wenyi Guo, Qiao Shi, Jia Yu, Weixing Wang
Recent studies demonstrated that apocynin, a nicotinamide adenine dinucleotide phosphate (NADPH) oxidase (NOX) inhibitor, significantly decreased acute pancreatitis‑associated inflammatory and oxidative stress parameters. In addition, apocynin was able to reduce ischemic reperfusion injury‑associated damage; however, the exact effects of apocynin on acute pancreatitis‑associated intestinal mucosal injury have yet to be fully clarified. The present study aimed to investigate the protective effects of apocynin on intestinal mucosal injury in a rat model of severe acute pancreatitis (SAP)...
October 2016: Molecular Medicine Reports
https://www.readbyqxmd.com/read/27555111/urine-intestinal-fatty-acid-binding-protein-predicts-acute-mesenteric-ischemia-in-patients
#10
Saad Y Salim, Pang Y Young, Thomas A Churchill, Rachel G Khadaroo
BACKGROUND: Acute mesenteric ischemia (AMI) has a high morbidity and mortality and often presents as a diagnostic challenge. Currently, there is no blood, urine, or radiologic tests that provide a definitive diagnosis of AMI. The aim of this study was to evaluate the clinical accuracy of urine intestinal fatty acid-binding protein (I-FABP) to diagnosis AMI. MATERIALS AND METHODS: Twenty patients referred to the Acute Care Surgery service at University of Alberta Hospital with suspected AMI taken to the operating room for definitive diagnosis were recruited...
July 16, 2016: Journal of Surgical Research
https://www.readbyqxmd.com/read/27511377/acute-gastrointestinal-manifestation-of-situs-inversus-abdominus
#11
K M Brown, J S Gundara, A Mittal
PURPOSE: Whilst situs inversus is associated with intestinal malrotation and volvulus particularly in infants, this is the first known report of acute intestinal obstruction in an adult patient with a situs anomaly specifically due to a congenital transmesenteric hernia. CASE: A 54-year-old woman presented with a 12-h history of progressive abdominal pain. Contrast-enhanced computed tomography scan of the abdomen revealed an incidental finding of situs inversus abdominus, ischemic small bowel obstruction and a potential occlusive thrombus of the superior mesenteric artery...
August 10, 2016: Hernia: the Journal of Hernias and Abdominal Wall Surgery
https://www.readbyqxmd.com/read/27501050/ischemic-post-conditioning-attenuates-acute-lung-injury-induced-by-intestinal-ischemia-reperfusion-in-mice-role-of-nrf2
#12
Qing-Tao Meng, Chen Cao, Yang Wu, Hui-Min Liu, Wei Li, Qian Sun, Rong Chen, Yong-Guang Xiao, Ling-Hua Tang, Ying Jiang, Yan Leng, Shao-Qing Lei, Chris C Lee, Devin M Barry, Xiangdong Chen, Zhong-Yuan Xia
Intestinal ischemic post-conditioning (IPo) protects against lung injury induced by intestinal ischemia-reperfusion (IIR) partly through promotion of expression and function of heme oxygenase-1 (HO-1). NF-E2-related factor-2 (Nrf2) is a key transcription factor that interacts with HO-1 and regulates antioxidant defense. However, the role of Nrf2 in IPo protection of IIR-induced pulmonary injury is not completely understood. Here we show that IPo significantly attenuated IIR-induced lung injury and suppressed oxidative stress and systemic inflammatory responses...
October 2016: Laboratory Investigation; a Journal of Technical Methods and Pathology
https://www.readbyqxmd.com/read/27497940/the-challenges-of-managing-and-following-up-a-case-of-short-bowel-in-eastern-europe
#13
Henry Ifeanyi Osakwe, Cristina Dragomir, Cristian Nicolescu, Eugen Sorin Boia
INTRODUCTION: This article reflects on the plight of patients with short bowel syndrome (SBS) in developing countries. SBS is life threatening, rare, complex and often not considered a priority by healthcare planners in the developing countries because of the high cost of treatment. Data was collected and analyzed from 3 different hospitals in two different countries (Romania and Austria) from November 2013 to February 2016 CASE PRESENTATION: The patient had an emergency surgery for volvulus as a result of an extensive ischemic necrosis, with just 80cm of the bowel left and no ileocecal valve after enterectomy...
2016: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/27474829/combination-of-diagnostic-laparoscopy-and-intraoperative-indocyanine-green-fluorescence-angiography-for-the-early-detection-of-intestinal-ischemia-not-detectable-at-ct-scan
#14
Giovanni Alemanno, Riccardo Somigli, Paolo Prosperi, Carlo Bergamini, Gherardo Maltinti, Alessio Giordano, Andrea Valeri
INTRODUCTION: Acute mesenteric ischemia is the most severe gastrointestinal complication of acute aortic dissection. The timing of diagnosis is of major importance, in fact the recognition of acute mesenteric ischemia often occurs too late due to the presence of unspecific symptoms and lack of reliable exams. Recently, indocyanine green fluorescence angiography has been adopted in order to measure blood perfusion and microcirculation. PRESENTATION OF CASE: We decided to perform a diagnostic laparoscopy with the support of intra-operative near-infrared indocyanine green fluorescence angiography, in order to detect an initial intestinal ischemia in a 68-year-old patient previously treated with a TEVAR procedure for a type-B aortic dissection...
2016: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/27413153/microbiota-dysbiosis-controls-the-neuroinflammatory-response-after-stroke
#15
Vikramjeet Singh, Stefan Roth, Gemma Llovera, Rebecca Sadler, Debora Garzetti, Bärbel Stecher, Martin Dichgans, Arthur Liesz
UNLABELLED: Acute brain ischemia induces a local neuroinflammatory reaction and alters peripheral immune homeostasis at the same time. Recent evidence has suggested a key role of the gut microbiota in autoimmune diseases by modulating immune homeostasis. Therefore, we investigated the mechanistic link among acute brain ischemia, microbiota alterations, and the immune response after brain injury. Using two distinct models of acute middle cerebral artery occlusion, we show by next-generation sequencing that large stroke lesions cause gut microbiota dysbiosis, which in turn affects stroke outcome via immune-mediated mechanisms...
July 13, 2016: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/27365888/amphetamine-related-ischemic-colitis-causing-gastrointestinal-bleeding
#16
Ragesh Panikkath, Deepa Panikkath
A 43-year-old woman presented with acute lower intestinal bleeding requiring blood transfusion. Multiple initial investigations did not reveal the cause of the bleeding. Colonoscopy performed 2 days later showed features suggestive of ischemic colitis. On detailed history, the patient admitted to using amphetamines, and her urine drug screen was positive for them. She was managed conservatively and advised not to use amphetamines again. She did not have any recurrence on 2-year follow-up.
July 2016: Proceedings of the Baylor University Medical Center
https://www.readbyqxmd.com/read/27353154/-mesenteric-venous-thrombosis-during-pregnancy-a-rare-cause-of-acute-ischaemia-of-the-small-intestine
#17
B M M Reiber, R R Gorter, M Tenhagen, H A Cense, A Demirkiran
BACKGROUND: Acute ischaemia of the small intestine is caused by mesenteric venous thrombosis in 5-15% of patients. The non-specific symptoms frequently lead to a diagnostic delay. CASE DESCRIPTION: A 30-year-old pregnant woman presented at the accident and emergency department with progressive abdominal pain, nausea and vomiting. During admission the patient developed signs of peritonitis. Diagnostic laparoscopy revealed a picture of mesenteric venous thrombosis, and we resected 170 cm ischemic small intestine...
2016: Nederlands Tijdschrift Voor Geneeskunde
https://www.readbyqxmd.com/read/27261632/giant-meckel-s-diverticulum-torsion-that-mimics-adnexal-pathology
#18
Serdar Kirmizi, Demet Aydogan Kirmizi, Reyhan Karagul, Kerem Tolan
Meckel's diverticulum is a real diverticulum located at the antimesenteric portion of intestinal loops and including all layers of the intestinal wall. It is the most common congenital anomaly of the gastrointestinal tract, and its incidence is 1-3%. Many asymptomatic cases are diagnosed when complications occur. A 23-year-old female patient applied to gynaecology emergency clinic with pelvic pain complaint. Laparotomy was performed with the diagnosis of acute abdomen because the physical examination and imaging studies did not exclude tuboovary pathology...
2016: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/27228089/intestinal-perforation-in-renal-transplant-recipients-a-single-center-experience-of-2123-recipients
#19
Kyriaki Kakavia, Demetrios Moris, Elli Karatza, John Bokos, Spiridon Vernadakis, Alexandros Barlas, Georgios Sotirchos, Konstantinos Diles, Spyridon Drakopoulos, Georgios Zavos
OBJECTIVES: Intestinal perforation remains a clinical challenge and potentially lethal complication in renal transplant recipients. Immunosuppression not only places the patient at risk for intestinal perforation but also masks classic clinical symptoms and signs of acute abdominal pain, leading to delayed diagnosis and proper treatment. The aim of our study is to present the experience of our center on the treatment of intestinal perforation in renal transplant recipients. MATERIALS AND METHODS: This study reported 11 patients (0...
May 26, 2016: Experimental and Clinical Transplantation
https://www.readbyqxmd.com/read/27193976/role-of-alkaline-phosphatase-intestine-isomerase-in-acute-mesenteric-ischemia-diagnosis
#20
Emin Lapsekili, Öner Menteş, Müjdat Balkan, Armağan Günal, Halil Yaman, Orhan Kozak, Yusuf Peker
BACKGROUND: The aim of the present study was to investigate the diagnostic value of alkaline phosphatase (ALP) intestine-isomerase, plasma lactate dehydrogenase (LDH), and D-dimer levels in acute mesenteric ischemia. METHODS: Thirty Wistar rats were divided into 5 groups of 6 rats each. In Group 1, blood samples were obtained to determine normal parameter levels. In the sham group, Group 2, blood samples were obtained following laparotomy. In Group 3, blood samples were obtained 2 hours after ligation...
December 0: Ulusal Travma Ve Acil Cerrahi Dergisi, Turkish Journal of Trauma & Emergency Surgery: TJTES
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