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https://www.readbyqxmd.com/read/28923370/nursing-students-perceptions-of-preparation-to-engage-in-patient-education
#1
Elizabeth Richard, Teresa Evans, Bev Williams
Patient teaching is a key component of graduate nursing practice. Nurses sometimes believe that their undergraduate teaching does not prepare them to engage in effective patient teaching. In addition, nursing students often do not use teaching resources when engaging in patient teaching. The aim of this focused ethnographic study was to determine if students in a CBL/PBL based learning undergraduate nursing program engage in patient teaching when they are in the clinical area. Focus groups and shorter individual interviews were used to ensure in-depth data collection...
September 9, 2017: Nurse Education in Practice
https://www.readbyqxmd.com/read/28915427/breast-lymphoma-in-a-patient-with-b-cell-non-hodgkin-lymphoma-a-case-report-study
#2
Spyridon Marinopoulos, Panagiotis Safioleas, Lamprini Skorda, Eleni Vassilopoulou, Flora Zagouri, Maria Sotiropoulou, Peter Drakakis, Constantine Dimitrakakis
INTRODUCTION: Breast involvement in Non Hodgkin Lymphoma is a rare entity as it accounts for 2.2% of all extranodal lymphomas. PRESENTATION OF CASE: A 59-year-old woman was referred to our Breast Unit because of two nodules of the right breast newly discovered during her annual mammography. Moreover, during the physical examination, a red-brown itchy lump of the scalp was discovered. The punch biopsies of the scalp lesion and ultrasound-guided core biopsies of both nodules of the right breast, revealed the presence of diffuse large B-cell Non Hodgkin Lymphoma in all tissue specimen sites...
September 7, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28894005/varicose-and-cheerio-collaborate-with-pebble-to-mediate-semaphorin-1a-reverse-signaling-in-drosophila
#3
Sangyun Jeong, Da-Som Yang, Young Gi Hong, Sarah P Mitchell, Matthew P Brown, Alex L Kolodkin
The transmembrane semaphorin Sema-1a acts as both a ligand and a receptor to regulate axon-axon repulsion during neural development. Pebble (Pbl), a Rho guanine nucleotide exchange factor, mediates Sema-1a reverse signaling through association with the N-terminal region of the Sema-1a intracellular domain (ICD), resulting in cytoskeletal reorganization. Here, we uncover two additional Sema-1a interacting proteins, varicose (Vari) and cheerio (Cher), each with neuronal functions required for motor axon pathfinding...
September 11, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28893071/a-model-of-collaboration-for-the-implementation-of-problem-based-learning-in-nursing-education-in-south-africa
#4
Mahlasela A Rakhudu, Mashudu Davhana-Maselesele, Ushonatefe Useh
BACKGROUND: The idea of collaboration between key stakeholders in nursing education for the implementation of problem-based learning (PBL) may have far-reaching implications for the institutions and students. MAIN OBJECTIVE: To develop a model of collaboration to facilitate the implementation of PBL in nursing education. METHODOLOGY: An exploratory sequential design was used. Qualitative data were collected from purposively recruited nurse educators from three universities in South Africa offering PBL and nurse managers from all the three hospitals in North West Province where PBL students are placed for clinical learning...
August 28, 2017: Curationis
https://www.readbyqxmd.com/read/28891721/the-regions-on-the-light-chain-of-botulinum-neurotoxin-type-a-recognized-by-t-cells-from-toxin-treated-cervical-dystonia-patients-the-complete-human-t-cell-recognition-map-of-the-toxin-molecule
#5
Minako Oshima, Philip Deitiker, Joseph Jankovic, M Zouhair Atassi
We have recently mapped the in vitro proliferative responses of T cells from botulinum neurotoxin type A (BoNT/A)-treated cervical dystonia (CD) patients with overlapping peptides encompassing BoNT/A heavy chain (residues 449-1296). In the present study, we determined the recognition profiles, by peripheral blood lymphocytes (PBL) from the same set of patients, of BoNT/A light (L) chain (residues 1-453) by using 32 synthetic overlapping peptides that encompassed the entire L chain. Profiles of the T-cell responses (expressed in stimulation index, SI; Z score based on transformed SI) to the peptides varied among the patients...
September 11, 2017: Immunological Investigations
https://www.readbyqxmd.com/read/28883212/verification-of-learning-effects-by-team-based-learning
#6
Shin-Ichi Ono, Yoshihisa Ito, Kumiko Ishige, Norio Inokuchi, Yasuhiro Kosuge, Satoru Asami, Megumi Izumisawa, Hiroko Kobayashi, Hiroyuki Hayashi, Takashi Suzuki, Yukinaga Kishikawa, Harumi Hata, Eiji Kose, Kei-Ichi Tabata
  It has been recommended that active learning methods, such as team-based learning (TBL) and problem-based learning (PBL), be introduced into university classes by the Central Council for Education. As such, for the past 3 years, we have implemented TBL in a medical therapeutics course for 4-year students. Based upon our experience, TBL is characterized as follows: TBL needs fewer teachers than PBL to conduct a TBL module. TBL enables both students and teachers to recognize and confirm the learning results from preparation and reviewing...
September 5, 2017: Yakugaku Zasshi: Journal of the Pharmaceutical Society of Japan
https://www.readbyqxmd.com/read/28878909/a-rare-case-of-epstein-barr-virus-related-plasmacytoma-involving-maxillary-sinus-mucosa
#7
Julie D Gibbs, Marino E Leon, Kenia Liu, Johnny Nguyen, Ling Zhang
Extramedullary plasmacytomas, Epstein-Bar virus (EBV) associated, are rarely encountered and usually have a fairly good clinical outcome. EBV+ plasmacytoma may cause a diagnostic dilemma as it phenotypically resembles an aggressive plasmablastic lymphoma (PBL). Herein, we report a unique case with maxillary EBV+ plasmacytoma from a 76-year-old immunocompetent individual.
September 2017: Clinical Case Reports
https://www.readbyqxmd.com/read/28862126/diffuse-large-b-cell-lymphoma-in-a-male-breast-a-rare-case-report
#8
Adelina Birceanu Corobea, Adrian Dumitru, Maria Sajin, Radu Poenaru, Ana Puşcaşu, Dragoş Chirita, Anca Evsei
Primary breast diffuse large B cell lymphoma (PBL) in male patients represents a rare clinical phenomenon and can imitate a breast carcinoma in its clinical presentation, so, therefore, the initial treatment for most patients remains surgery. Prompt diagnosis associating subsequent treatment combining chemotherapy and radiotherapy are of the utmost importance. We herein report a 56 years old male patient diagnosed with diffuse large B cell lymphoma, after clinically presenting with a visible tumor in the left breast and showing no axillary lymphadenopathy...
July 2017: Chirurgia
https://www.readbyqxmd.com/read/28860565/interleukin-6-dependent-growth-in-a-newly-established-plasmablastic-lymphoma-cell-line-and-its-therapeutic-targets
#9
Sohtaro Mine, Tsunekazu Hishima, Akihiko Suganuma, Hitomi Fukumoto, Yuko Sato, Michiyo Kataoka, Tsuyoshi Sekizuka, Makoto Kuroda, Tadaki Suzuki, Hideki Hasegawa, Masashi Fukayama, Harutaka Katano
Plasmablastic lymphoma (PBL) is a rare, highly aggressive subtype of non-Hodgkin lymphoma with plasma-cell differentiation occurring typically in immune-suppressed patients such as those with AIDS. This study reports the establishment and characterization of a new cell line, PBL-1, derived from a patient with AIDS-associated PBL. Morphological assessment of PBL-1 indicated plasma-cell differentiation with a CD20(-) CD38(+) CD138(+) immunophenotype and IgH/c-myc translocation. The cell line harbours Epstein-Barr virus, but a 52...
August 31, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28859649/the-integration-of-blended-learning-into-an-occupational-therapy-curriculum-a-qualitative-reflection
#10
Paula Barnard-Ashton, Alan Rothberg, Patricia McInerney
BACKGROUND: This paper presents a critical reflection of the integration of Blended Learning (BL) into an undergraduate occupational therapy curriculum which was delivered through Problem Based Learning (PBL). METHOD: This is a qualitative reflection of a Participatory Action Research (PAR) study using Brookfield's model for critical reflection of an educator's practice. The model uses four 'lenses' through which to focus enquiry: Lens 1) our autobiography as a learner of practice; Lens 2) our learners' eyes; Lens 3) our colleagues' experiences; and Lens 4) the theoretical literature...
August 17, 2017: BMC Medical Education
https://www.readbyqxmd.com/read/28846213/proteome-dynamics-in-biobanked-horse-peripheral-blood-derived-lymphocytes-pbl-with-induced-autoimmune-uveitis
#11
Stefanie M Hauck, Marlen F Lepper, Michael Hertl, Walter Sekundo, Cornelia A Deeg
Equine recurrent uveitis (ERU) is the only spontaneous model for recurrent autoimmune uveitis in humans, where T cells target retinal proteins. Differences between normal and autoaggressive lymphocytes were identified in this study by analyzing peripheral blood derived lymphocytes (PBL) proteomes from the same case with IRBP-induced uveitis sampled before (day 0), during (day 15) and after uveitic attack (day 23). Relative protein abundances of PBL were investigated in a quantitative, label-free differential proteome analysis in cells that were kept frozen for 14 years since the initial experiment...
August 28, 2017: Proteomics
https://www.readbyqxmd.com/read/28846180/synergistic-activity-of-sorafenib-and-betulinic-acid-against-clonogenic-activity-of-non-small-cell-lung-cancer-cells
#12
Justyna Kutkowska, Leon Strzadala, Andrzej Rapak
The highly selective multi-targeted agent - sorafenib - is an inhibitor of a number of intracellular signaling kinases with anti-proliferative, anti-angiogenic and pro-apoptotic effects in various types of tumors, including human non-small cell lung cancer (NSCLC). Betulin displays a broad spectrum of biological and pharmacological properties, including the anticancer and chemopreventive activity. Combination of drugs with different targets is a logical approach to overcome multilevel cross-stimulation among key signaling pathways in NSCLC progression...
August 28, 2017: Cancer Science
https://www.readbyqxmd.com/read/28844914/comparison-of-the-total-and-hidden-blood-loss-in-patients-undergoing-open-and-minimally-invasive-transforaminal-lumbar-interbody-fusion
#13
Hui Zhang, Ze-Xin Chen, Ze-Ming Sun, Chao Jiang, Wen-Fei Ni, Yan Lin, Yao-Sen Wu
PURPOSE: This study examined the volume of hidden blood loss (HBL) and compared perioperative blood loss between minimally invasive transforaminal lumbar interbody fusion (MI-TLIF) and open transforaminal lumbar interbody fusion (O-TLIF). METHODS: Forty-eight patients who were treated with MI-TLIF and 59 patients treated with O-TLIF were enrolled in this study. Patient's height, weight, and preoperative and postoperative hematocrit (Hct) were recorded and used to calculate total blood loss (TBL) according to Gross's formula...
August 24, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28842181/splenic-%C3%AE-%C3%AE-t-cell-subsets-can-be-separated-by-a-novel-mab-specific-for-two-cd45-isoforms
#14
Daniela Huhle, Sieglinde Hirmer, Thomas W Göbel
CD45 isoforms have been identified in a variety of different species and mab against various isoforms have been instrumental to define cellular subsets. In the process of generating novel mab against chicken γδ T cells two mab with specificity for CD45 were identified and characterized. The analysis of the chicken CD45 genomic structure suggested three exons being involved in alternative splicing. We cloned and expressed the full length CD45 isoform and three shorter isoforms. While the 7D12 mab reacted with all of these isoforms, the 8B1 mab selectively reacted with two short isoforms lacking either exons 3 and 5 or exons 3, 5 and 6...
August 24, 2017: Developmental and Comparative Immunology
https://www.readbyqxmd.com/read/28839526/primary-breast-lymphoma-a-case-report-and-review-of-the-literature
#15
Kamal E H Mohamed, Rusha A E Ali
Primary breast lymphoma (PBL) represents 0.04-0.5% of all malignant breast tumors, <1% of all patients with non-Hodgkin's lymphomas and 1.7-2.2% of all patients with extra nodal lymphomas. Despite the high prevalence of breast cancer, primary breast lymphoma is very rare. We report a rare case of PBL, successfully treated with surgery, chemotherapy and radiotherapy. This is the first case of PBL to be reported from Sudan to our knowledge.
June 7, 2017: Clinics and Practice
https://www.readbyqxmd.com/read/28839450/diffuse-large-b-cell-breast-lymphoma-a-case-series
#16
REVIEW
Afaf H Al Battah, Einas A Al Kuwari, Zsolt Hascsi, Abdulqadir J Nashwan, Halima Elomari, Hisham Elsabah, Safa Al Azawi, Samah Kohla, Dina Soliman, Mohamed A Yassin
Primary breast lymphoma (PBL) is a rare disease, and few clinicohistopathologic features of the disease have been discussed in previous studies. It represents 2.2% of extranodal lymphomas and constitutes 0.04% to 0.5% of malignant breast neoplasms, despite the clinical and radiographic similarities between breast lymphoma and carcinoma, the prognosis, as reported in the literature, varies. No consensus exists on the best way to treat PBL. However, radiotherapy and chemotherapy were used alone or in combination to treat various cases of PBL...
2017: Clinical Medicine Insights. Blood Disorders
https://www.readbyqxmd.com/read/28829362/content-analysis-of-student-essays-after-attending-a-problem-based-learning-course-facilitating-the-development-of-critical-thinking-and-communication-skills-in-japanese-nursing-students
#17
Tomoya Itatani, Kyoko Nagata, Kiyoko Yanagihara, Noriko Tabuchi
The importance of active learning has continued to increase in Japan. The authors conducted classes for first-year students who entered the nursing program using the problem-based learning method which is a kind of active learning. Students discussed social topics in classes. The purposes of this study were to analyze the post-class essay, describe logical and critical thinking after attended a Problem-Based Learning (PBL) course. The authors used Mayring's methodology for qualitative content analysis and text mining...
August 22, 2017: Healthcare (Basel, Switzerland)
https://www.readbyqxmd.com/read/28818008/occupational-therapy-student-experiences-of-a-university-mental-health-course-based-on-an-integrated-application-of-problem-based-and-team-based-learning
#18
Annika Lexén, Jenny Hultqvist, Gunilla Amnér
BACKGROUND: The goal of problem-based and team-based learning (PBL/TBL) is to maximize student engagement and encourage interactive learning. Combining these methods in course design is described as a win-win situation that optimizes student learning, professional development, and uses varied teaching approaches that fit well within health science. More research is needed in the effectiveness of such a hybrid approach. OBJECTIVES: The aim of this study was to explore student experiences of a newly developed mental health course based on an integrated application of PBL and TBL in a university occupational therapy program in Sweden...
August 17, 2017: Scandinavian Journal of Occupational Therapy
https://www.readbyqxmd.com/read/28768111/providing-pediatric-palliative-care-education-using-problem-based-learning
#19
Karen Moody, Marlene McHugh, Rebecca Baker, Hillel Cohen, Priya Pinto, Stephanie Deutsch, Ruth O Santizo, Miriam Schechter, James Fausto, Pablo Joo
BACKGROUND: The Institute of Medicine and the American Academy of Pediatrics has called for improvement in education and training of pediatricians in pediatric palliative care (PPC). Given the shortage of PPC physicians and the immediate need for PPC medical education, this study reports the outcomes of a problem-based learning (PBL) module facilitated by academic general and subspecialty pediatric faculty (non-PPC specialists) to third year medical students. Objectives/Setting: To test the effectiveness of a PPC-PBL module on third year medical students' and pediatric faculty's declarative knowledge, attitudes toward, perceived exposure, and self-assessed competency in PPC objectives...
August 2, 2017: Journal of Palliative Medicine
https://www.readbyqxmd.com/read/28765438/dental-faculty-members-pedagogic-beliefs-and-curriculum-aims-in-problem-based-learning-an-exploratory-study
#20
HsingChi von Bergmann, Judith Walker, Kirsten R Dalrymple, Charles F Shuler
The aims of this exploratory study were to explore dental faculty members' views and beliefs regarding knowledge, the dental profession, and teaching and learning and to determine how these views related to their problem-based learning (PBL) instructional practices. Prior to a PBL in dental education conference held in 2011, all attendees were invited to complete a survey focused on their pedagogical beliefs and practices in PBL. Out of a possible 55 participants, 28 responded. Additionally, during the conference, a forum was held in which preliminary survey findings were shared and participants contributed to focus group data collection...
August 2017: Journal of Dental Education
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