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Radial Endobronchial ultrasound

Maurizio Bernasconi, Alessio Casutt, Angela Koutsokera, Igor Letovanec, Frédéric Tissot, Laurent P Nicod, Alban Lovis
The role of radial-endobronchial ultrasound (R-EBUS) assisted transbronchial biopsy (TBB) for the diagnosis of peripheral pulmonary lesions is well established. However, no study has addressed its safety and value in hemato-oncological patients presenting with non-resolving infiltrates during persistent febrile neutropenia. To assess safety and feasibility of R-EBUS assisted TBB in severe thrombocytopenic and neutropenic patients. Over a period of 18 months, eight patients were assessed with R-EBUS assisted TBB after adequate platelet transfusion...
October 4, 2016: Lung
Katarzyna Gorska, Piotr Korczynski, Michal Mierzejewski, Justyna Kosciuch, Malgorzata Zukowska, Marta Maskey-Warzechowska, Rafal Krenke
INTRODUCTION: Airway remodeling in asthma and chronic obstructive pulmonary disease (COPD) results in bronchial wall thickening. Bronchial wall thickness (BWT) can be assessed in high-resolution computed tomography (HRCT) and endobronchial ultrasound (EBUS). AIMS: To compare BWT measured by EBUS and HRCT in patients with mild-to-moderate asthma and COPD, and to evaluate the relationship between the BWT and pulmonary function. METHODS: The study included patients with mild-to-moderate asthma (n = 24), COPD (n = 36) and controls (n = 12)...
August 2016: Respiratory Medicine
Harry D Georgiou, John Taverner, Louis B Irving, Daniel P Steinfort
BACKGROUND: Peripheral pulmonary lesion (PPL) is a common scenario in patients with chronic obstructive pulmonary disease (COPD) and represents a high risk of malignancy. Severe COPD is associated with higher complication rates following percutaneous biopsy, and routine bronchoscopy. Safety and diagnostic performance of radial endobronchial ultrasound bronchoscopy (R-EBUS) in patients with advanced COPD has not been previously assessed. METHODS: We examined a retrospective cohort of patients with advanced COPD undergoing R-EBUS for the evaluation of PPL...
July 2016: Journal of Bronchology & Interventional Pulmonology
Fumihiro Asano
No abstract text is available yet for this article.
July 2016: Journal of Bronchology & Interventional Pulmonology
Chun-Hua Xu, Li-Ke Yu, Lan Cao, Rusong Yang, Jun Yan, Zheng-Cheng Liu, Yan Wang
The aim of this study was to assess the clinical value of radial probe endobronchial ultrasound (RP-EBUS)-guided localization of solitary pulmonary nodules (SPNs) with the combination of ultrathin bronchoscopy and methylene blue prior to video-assisted thoracoscopic surgery (VATS). An ultrathin bronchoscope was used to localize the lesions under RP-EBUS guidance in 48 patients (18 men and 30 women; age range, 41-72 years; mean age, 54 years), who subsequently underwent VATS resection. The lesion size, distance from the parietal pleura, localization time and complications were evaluated...
August 2016: Molecular and Clinical Oncology
Fumihiro Asano
Bronchoscopy to examine peripheral pulmonary lesions is performed using a bronchoscope with an outer diameter of 5-6mm under fluoroscopy, but the diagnostic yield can be insufficient. Problems with transbronchial biopsy include a limited range of bronchoscope insertion, difficulty in guiding a bronchoscope and biopsy instruments to lesions, and insufficient confirmation of the arrival of biopsy instruments at the target lesion; as such, new techniques have been used to overcome these individual problems. Radial-endobronchial ultrasound is used to identify peripheral pulmonary lesions and sampling sites...
July 2016: Respiratory Investigation
Stamatis Katsenos, Stavros Archondakis
No abstract text is available yet for this article.
September 2016: Diagnostic Cytopathology
Alexander C Chen, Andrea Loiselle, Li Zhou, Jack Baty, David Misselhorn
RATIONALE: Peripheral pulmonary lesions requiring a diagnosis continue to present challenges to clinicians. One significant barrier is the inability to reliably locate peripheral lesions by bronchoscopic approaches. Multiplanar computed tomographic (CT) scan reconstruction is available to most physicians and provides axial, coronal, and sagittal images that may be used to estimate target lesion location and guide bronchoscopists during procedures. OBJECTIVES: This study was performed to evaluate a systematic method of CT-anatomic correlation based on multiplanar reconstruction CT scanning with monoplanar fluoroscopy during bronchoscopy to locate peripheral pulmonary lesions and confirm lesion location, using radial probe endobronchial ultrasound...
September 2016: Annals of the American Thoracic Society
Guler Ozgul, Erdogan Cetinkaya, Mehmet Akif Ozgul, Yasin Abul, Atayla Gencoglu, Emine Kamiloglu, Sule Gul, H Erhan Dincer
BACKGROUND AND OBJECTIVES: Electromagnetic navigation bronchoscopy (ENB) is a promising new technology to increase the diagnostic yield of peripheral lung and mediastinal lesions. Conventional flexible bronchoscopy has a limited yield in peripheral pulmonary lesions, even in experienced hands. Radial endobronchial ultrasound (r-EBUS) with its real-time imaging capability can help to diagnose peripheral pulmonary lesions. In the present study, we aimed to investigate the diagnostic yield and safety of ENB with or without r-EBUS for peripheral lung lesions...
May 2016: Endoscopic Ultrasound
Manabu Hayama, Norio Okamoto, Hidekazu Suzuki, Motohiro Tamiya, Takayuki Shiroyama, Ayako Tanaka, Takuji Nishida, Takashi Nishihara, Nobuko Uehara, Naoko Morishita, Kunimitsu Kawahara, Tomonori Hirashima
BACKGROUND: Radial endobronchial ultrasound with a guide sheath (EBUS-GS) has improved the diagnostic outcomes of peripheral lung lesions. However, to our knowledge, reports on the use of EBUS-GS for diagnosis of cavitary lesions are unavailable. Therefore, this study aimed to assess the effectiveness and safety of EBUS-GS for diagnosis of peripheral cavitary lung lesions (PCLLs). METHODS: This study was a single-institution retrospective review of PCLLs examined by using EBUS-GS between July 2013 and October 2015...
2016: BMC Pulmonary Medicine
Florian Guisier, Mathieu Salaün, Samy Lachkar, Aude Lamy, Nicolas Piton, Bérengère Obstoy, Jean-Christophe Sabourin, Luc Thiberville
BACKGROUND AND OBJECTIVE: Treatment optimization of non-squamous non-small-cell lung cancers (nonSq-NSCLC) relies on the molecular analysis of the tumour. We aimed to assess the predictive factors of molecular analysis feasibility (MAF) from samples of peripheral nonSq-NSCLC obtained by radial endobronchial ultrasound bronchoscopy (r-EBUS) and 1.5 mm microbiopsy forceps. METHODS: We reviewed data from consecutive peripheral lung nodules sampled with r-EBUS between January 2012 and July 2014 at a single French University Hospital...
May 2016: Respirology: Official Journal of the Asian Pacific Society of Respirology
Lakshmi Mudambi, David E Ost
PURPOSE OF REVIEW: The review describes recent advances in bronchoscopic modalities used to diagnose peripheral pulmonary lesions. RECENT FINDINGS: The pooled diagnostic yield and sensitivity of radial probe endobronchial ultrasound (r-EBUS) has been reported to be 56% for lesions less than 2 cm and 78% for lesions more than 2 cm and 73%, respectively. The pooled diagnostic yield and sensitivity of electromagnetic navigational bronchoscopy (ENB) has been reported to be 65 and 71%, respectively...
July 2016: Current Opinion in Pulmonary Medicine
Inderpaul Singh Sehgal, Sahajal Dhooria, Ashutosh N Aggarwal, Digambar Behera, Ritesh Agarwal
Radial probe endobronchial ultrasound (EBUS) helps in the evaluation and sampling of peripheral pulmonary lesions (nodules, masses, consolidation), and has been demonstrated a safer alternative to computed tomography guided procedure, especially in lesions that are away from the chest wall. Although radial probe EBUS has been available for more than two decades, there is no report from the Indian subcontinent. Herein, we describe two cases of peripheral lung lesions that were successfully sampled with the use of radial probe EBUS...
March 2016: Lung India: Official Organ of Indian Chest Society
Ray W Shepherd
PURPOSE OF REVIEW: Peripheral pulmonary lesions (PPL) are being diagnosed with increasing frequency, especially with the increased use of chest computed tomography (CT). Depending on the location and size, these lesions often present a diagnostic challenge in terms of the low yield of traditional bronchoscopic biopsy techniques or the risks of a percutaneous biopsy approach. RECENT FINDINGS: Over the last several years, several different image-guided bronchoscopy techniques have emerged, including virtual bronchoscopic navigation, electromagnetic navigation bronchoscopy, radial endobronchial ultrasound, and ultrathin bronchoscopy...
May 2016: Current Opinion in Pulmonary Medicine
Changguo Wang, Daxiong Zeng, Wei Lei, Junhong Jiang, Yehan Zhu, Jian'an Huang
OBJECTIVE: To evaluate the value of computed tomography-guided percutaneous needle biopsy (CT-PNB) and radial probe endobronchial ultrasound-guided transbronchial lung biopsy (EBUS-TBLB) in the diagnosis of peripheral pulmonary lesions(PPLs). METHODS: The clinical data of 213 patients who were diagnosed as to have PPLs in the First Affiliated Hospital of Soochow University between December 1, 2012 and October 1, 2014 were studied retrospectively. The patients were divided into CT-PNB group and EBUS-TBLB group, according to biopsy methods...
December 2015: Chinese Journal of Tuberculosis and Respiratory Diseases
Chia-Hung Chen, Wen-Chien Cheng, Biing-Ru Wu, Chih-Yu Chen, Wei-Chun Chen, Te-Chun Hsia, Wei-Chih Liao, Chih-Yen Tu, Chuen-Ming Shih, Wu-Huei Hsu, Ko-Pen Wang
BACKGROUND: Rapid on-site evaluation (ROSE) of cytologic specimens is a useful ancillary technique in needle aspiration procedures of pulmonary/mediastinal lesions, but few reports had been carried out to confirm the utility in the diagnosis of peripheral pulmonary lesions (PPLs) by radial probe endobronchial ultrasound (R-EBUS). METHODS: To evaluate the impact of ROSE on the diagnostic yield of R-EBUS for PPLs, we retrospectively analyzed the diagnostic yields of transbronchial biopsy (TBB) or brushing using R-EBUS for patients with PPLs in a tertiary university hospital from December 2012 to December 2014...
December 2015: Journal of Thoracic Disease
Bojan Zaric, Vladimir Stojsic, Vladimir Carapic, Tomi Kovacevic, Goran Stojanovic, Milana Panjkovic, Ioannis Kioumis, Kaid Darwiche, Konstantinos Zarogoulidis, Grigoris Stratakos, Drosos Tsavlis, Wolfgang Hohenforst-Schmidt, Georgia Pitsiou, Athanasios Zissimopoulos, Nikos Sachpekidis, Ilias Karapantzos, Chrysanthi Karapantzou, Paul Zarogoulidis, Branislav Perin
BACKGROUND: EBUS guided trans-bronchial biopsy became routine in diagnosis of peripheral pulmonary lesions (PPL). Suction catheter-biopsy is a technique for obtaining a tissue sample from peripheral lung parenchyma. Aim of this study was to evaluate diagnostic efficiency, feasibility and safety of EBUS guided suction catheter-biopsy (SCB) in comparison to trans-bronchial biopsy (TBB) in diagnosis of PPL. The main intention was to demonstrate non-inferiority of the technique over trans-bronchial biopsy, especially when used under navigation of the EBUS...
2016: Journal of Cancer
Amal Durakovic, Henrik Andersen, Anders Christiansen, Irena Hammen
BACKGROUND: The purpose of the current study was to clarify the sensitivity and complication rate of the radial (endobronchial ultrasound, EBUS) without the use of guide-sheath (GS) and fluoroscopy for lung cancer (LC), by measuring the distance from the orifice of the bronchus to the pulmonary lesion, as well as to analyze factors that can predict the diagnostic outcome. MATERIALS AND METHODS: A total of 147 patients with peripheral pulmonary lesions (PPL) underwent radial EBUS-guided transbronchial biopsy (TBB) in between August 1, 2013, and August 31, 2014...
2015: European Clinical Respiratory Journal
Manabu Hayama, Takehiro Izumo, Christine Chavez, Yuji Matsumoto, Takaaki Tsuchida, Shinji Sasada
BACKGROUND: Endobronchial ultrasound with a guide sheath (EBUS-GS) has resulted to better diagnostic outcome for peripheral pulmonary lesions (PPLs), although the yield is not satisfactory for lesions that cannot be located by EBUS. We aimed to evaluate whether the addition of a new technique, transbronchial needle aspiration through a guide sheath (GS-TBNA), can increase the yield for these cases. METHODS: This was a retrospective review of cases that were not located by EBUS during EBUS-GS for PPL diagnosis...
November 25, 2015: Clinical Respiratory Journal
Calvin S H Ng, Simon C H Yu, Rainbow W H Lau, Anthony P C Yim
Electromagnetic navigational bronchoscopy-guided biopsy of small pulmonary nodules can be challenging. Navigational error of the system and movement of the biopsy tool during its deployment adversely affect biopsy success. Furthermore, conventional methods to confirm navigational success such as fluoroscopy and radial endobronchial ultrasound become less useful for the biopsy of small lesions. A hybrid operating theatre can provide unparalleled real-time imaging through DynaCT scan to guide and confirm successful navigation and biopsy of difficult-to-reach or small lesions...
January 2016: European Journal of Cardio-thoracic Surgery
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