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Lobat Tayebi

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https://www.readbyqxmd.com/read/29628249/dextran-hydrogels-incorporated-with-bioactive-glass-ceramic-nanocomposite-scaffolds-for-bone-tissue-engineering
#1
Parisa Nikpour, Hamed Salimi-Kenari, Farahnaz Fahimipour, Sayed Mahmood Rabiee, Mohammad Imani, Erfan Dashtimoghadam, Lobat Tayebi
A series of nanocomposite scaffolds comprised of dextran (Dex) and sol-gel derived bioactive glass ceramic nanoparticles (nBGC: 0-16 (wt%)) were fabricated as bioactive scaffolds for bone tissue engineering. Scanning electron microscopy showed Dex/nBGC scaffolds were consisting of a porous 3D microstructure with an average pore size of 240 μm. Energy-dispersive x-ray spectroscopy illustrated nBGC nanoparticles were homogenously distributed within the Dex matrix at low nBGC content (2 wt%), while agglomeration was observed at higher nBGC contents...
June 15, 2018: Carbohydrate Polymers
https://www.readbyqxmd.com/read/29611900/in-vitro-effect-of-graphene-structures-as-an-osteoinductive-factor-in-bone-tissue-engineering-a-systematic-review
#2
REVIEW
Dorsa Mohammadrezaei, Hossein Golzar, Maryam Rezai Rad, Meisam Omidi, Hamid Rashedi, Fatemeh Yazdian, Arash Khojasteh, Lobat Tayebi
Graphene and its derivatives have been well-known as influential factors in differentiating stem/progenitor cells towards the osteoblastic lineage. However, there have been many controversies in the literature regarding the parameters effect on bone regeneration, including graphene concentration, size, type, dimension, hydrophilicity, functionalization, and composition. This study attempts to produce a comprehensive review regarding the given parameters and their effects on stimulating cell behaviors such as proliferation, viability, attachment and osteogenic differentiation...
April 3, 2018: Journal of Biomedical Materials Research. Part A
https://www.readbyqxmd.com/read/29609510/immunohistochemical-expression-of-tlr-4-in-temporomandibular-joint-dysfunction
#3
Luis Eduardo Almeida, Kyle Hresko, Adam Sorenson, Seth Butcher, Lobat Tayebi, Rosalia Leonardi, Carla Loreto, Jose Bosio, Flavio Camejo, Andrea Doetzer
Objective Toll-like receptor 4 (TLR-4) is a transmembrane protein involved in the innate immune system and has been implicated in the pathogenesis of temporomandibular joint dysfunction (TMD). The purpose of this study was to histologically examine the level of expression of TLR-4 relative to severity of TMD. Methods Thirty-one human TMJ disc samples were immunostained for TLR-4 and evaluated for intensity of stain. Among the samples, 8 were control samples, 16 were from patients with anterior disc displacement with reduction (ADDwR), and 7 were from patients with anterior disc displacement without reduction (ADDwoR)...
April 2, 2018: Cranio: the Journal of Craniomandibular Practice
https://www.readbyqxmd.com/read/29519424/3d-printed-membrane-for-guided-tissue-regeneration
#4
Lobat Tayebi, Morteza Rasoulianboroujeni, Keyvan Moharamzadeh, Thafar K D Almela, Zhanfeng Cui, Hua Ye
Three-dimensional (3D) printing is currently being intensely studied for a diverse set of applications, including the development of bioengineered tissues, as well as the production of functional biomedical materials and devices for dental and orthopedic applications. The aim of this study was to develop and characterize a 3D-printed hybrid construct that can be potentially suitable for guided tissue regeneration (GTR). For this purpose, the rheology analyses have been performed on different bioinks and a specific solution comprising 8% gelatin, 2% elastin and 0...
March 1, 2018: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/29503205/poly-lactic-co-glycolic-acid-plga-tio-2-nanotube-bioactive-composite-as-a-novel-scaffold-for-bone-tissue-engineering-in-vitro-and-in-vivo-studies
#5
Hossein Eslami, Hamidreza Azimi Lisar, Tahereh Sadat Jafarzadeh Kashi, Mohammadreza Tahriri, Mojtaba Ansari, Tohid Rafiei, Farshid Bastami, Alireza Shahin-Shamsabadi, Fatemeh Mashhadi Abbas, Lobat Tayebi
The aim of this study was to synthesize and characterize novel three-dimensional porous scaffolds made of poly (lactic-co-glycolic acid)/TiO2 nanotube (TNT) composite microspheres for bone tissue engineering applications. The incorporation of TNT greatly increases mechanical properties of PLGA/TNT microsphere-sintered scaffold. The experimental results exhibit that the PLGA/0.5 wt% TNT scaffold sintered at 100 °C for 3 h showed the best mechanical properties and a proper pore structure for tissue engineering...
March 1, 2018: Biologicals: Journal of the International Association of Biological Standardization
https://www.readbyqxmd.com/read/29475368/immunological-compatibility-status-of-placenta-derived-stem-cells-is-mediated-by-scaffold-3d-structure
#6
Sara Azizian, Fatemeh Khatami, Khashayar Modaresifar, Nariman Mosaffa, Habibollah Peirovi, Lobat Tayebi, Soheyl Bahrami, Heinz Redl, Hassan Niknejad
Placenta-derived amniotic epithelial cells (AECs), a great cell source for tissue engineering and stem cell therapy, are immunologically inert in their native state; however, immunological changes in these cells after culture and differentiation have challenged their applications. The aim of this study was to investigate the effect of 2D and 3D scaffolds on human lymphocyte antigens (HLA) expression by AECs. The effect of different preparation parameters including pre-freezing time and temperature was evaluated on 3D chitosan-gelatine scaffolds properties...
February 23, 2018: Artificial Cells, Nanomedicine, and Biotechnology
https://www.readbyqxmd.com/read/29408655/nanomagnetic-mediated-drug-delivery-for-the-treatment-of-dental-disease
#7
Yadong Ji, Seung K Choi, Ahmed S Sultan, Kong Chuncai, Xiaoying Lin, Erfan Dashtimoghadam, Mary Anne Melo, Michael Weir, Huakun Xu, Lobat Tayebi, Zhihong Nie, Didier A Depireux, Radi Masri
Maintaining the vitality of the dental pulp, the highly innervated and highly vascular, innermost layer of the tooth, is a critical goal of any dental procedure. Upon injury, targeting the pulp with specific therapies is challenging because it is encased in hard tissues. This project describes a method that can effectively deliver therapeutic agents to the pulp. This method relies on the use of nanoparticles that can be actively steered using magnetic forces to the pulp, traveling through naturally occurring channels in the dentin (the middle layer of the tooth)...
February 1, 2018: Nanomedicine: Nanotechnology, Biology, and Medicine
https://www.readbyqxmd.com/read/29327658/immunohistochemical-analysis-of-il-1-receptor-1-in-the-discs-of-patients-with-temporomandibular-joint-dysfunction
#8
Luis Eduardo Almeida, Adam Sorenson, Kyle Hresko, Seth Butcher, Rosalia Leonardi, Carla Loreto, Jose Bosio, Lobat Tayebi, Andrea Doetzer
Objective Temporomandibular joint dysfunction (TMD) may affect a patient's quality of life, and one of the etiologies can be anterior disc displacement with reduction (ADDwR) and anterior disc displacement without reduction (ADDWoR). Interleukin 1 Receptor 1 (IL-1R1) is a membrane receptor that plays an important role on initiating immune and inflammatory response by binding the agonists ligands of IL-1 alpha and IL-1 beta. Therefore, the aim of this study was to evaluate, through immunohistochemical analysis, the association of IL-1R1 with TMD...
January 12, 2018: Cranio: the Journal of Craniomandibular Practice
https://www.readbyqxmd.com/read/29322600/using-enamel-matrix-derivative-to-improve-treatment-efficacy-in-periodontal-furcation-defects
#9
REVIEW
Reza Masaeli, Kavosh Zandsalimi, Zahra Lotfi, Lobat Tayebi
PURPOSE: Furcations are complicated periodontal defects. Untreated furcations lead to loss of the involved teeth and supporting tissues. It has been demonstrated that regenerative biomaterials are beneficial in reconstruction of the bone surrounding furcation-affected teeth. These biomaterials range from bone grafts and nonresorbable/resorbable barrier membranes to biologics that are able to trigger inactive regenerative processes in periodontal tissues. Selection of appropriate material(s) to treat furcations is challenging...
January 11, 2018: Journal of Prosthodontics: Official Journal of the American College of Prosthodontists
https://www.readbyqxmd.com/read/29109030/layer-by-layer-assembly-of-graphene-oxide-on-thermosensitive-liposomes-for-photo-chemotherapy
#10
Mohadeseh Hashemi, Meisam Omidi, Bharadwaj Muralidharan, Lobat Tayebi, Matthew J Herpin, Mohammad Ali Mohagheghi, Javad Mohammadi, Hugh D C Smyth, Thomas E Milner
Stimuli responsive polyelectrolyte nanoparticles have been developed for chemo-photothermal destruction of breast cancer cells. This novel system, called layer by layer Lipo-graph (LBL Lipo-graph), is composed of alternate layers of graphene oxide (GO) and graphene oxide conjugated poly (l-lysine) (GO-PLL) deposited on cationic liposomes encapsulating doxorubicin. Various concentrations of GO and GO-PLL were examined and the optimal LBL Lipo-graph was found to have a particle size of 267.9 ± 13 nm, zeta potential of +43...
January 2018: Acta Biomaterialia
https://www.readbyqxmd.com/read/29054688/collagenous-matrix-supported-by-a-3d-printed-scaffold-for-osteogenic-differentiation-of-dental-pulp-cells
#11
Farahnaz Fahimipour, Erfan Dashtimoghadam, Morteza Rasoulianboroujeni, Mostafa Yazdimamaghani, Kimia Khoshroo, Mohammadreza Tahriri, Amir Yadegari, Jose A Gonzalez, Daryoosh Vashaee, Douglas C Lobner, Tahereh S Jafarzadeh Kashi, Lobat Tayebi
OBJECTIVE: A systematic characterization of hybrid scaffolds, fabricated based on combinatorial additive manufacturing technique and freeze-drying method, is presented as a new platform for osteoblastic differentiation of dental pulp cells (DPCs). METHODS: The scaffolds were consisted of a collagenous matrix embedded in a 3D-printed beta-tricalcium phosphate (β-TCP) as the mineral phase. The developed construct design was intended to achieve mechanical robustness owing to 3D-printed β-TCP scaffold, and biologically active 3D cell culture matrix pertaining to the Collagen extracellular matrix...
October 17, 2017: Dental Materials: Official Publication of the Academy of Dental Materials
https://www.readbyqxmd.com/read/28832260/development-of-chitosan-gelatin-keratin-composite-containing-hydrocortisone-sodium-succinate-as-a-buccal-mucoadhesive-patch-to-treat-desquamative-gingivitis
#12
Zahra Davoudi, Mohammad Rabiee, Behzad Houshmand, Niloofar Eslahi, Kimia Khoshroo, Morteza Rasoulianboroujeni, Mohammadreza Tahriri, Lobat Tayebi
The aim of this research was to develop chitosan/gelatin/keratin composite containing hydrocortisone sodium succinate as a buccal mucoadhesive patch to treat desquamative gingivitis, which was fabricated through an environmental friendly process. Mucoadhesive films increase the advantage of higher efficiency and drug localization in the affected region. In this research, mucoadhesive films, for the release of hydrocortisone sodium succinate, were prepared using different ratios of chitosan, gelatin and keratin...
January 2018: Drug Development and Industrial Pharmacy
https://www.readbyqxmd.com/read/28817711/on-chip-detection-of-gel-transition-temperature-using-a-novel-micro-thermomechanical-method
#13
Tsenguun Byambadorj, Erfan Dashtimoghadam, Mohamadali Malakoutian, Benyamin Davaji, Lobat Tayebi, James E Richie, Chung Hoon Lee
We present a new thermomechanical method and a platform to measure the phase transition temperature at microscale. A thin film metal sensor on a membrane simultaneously measures both temperature and mechanical strain of the sample during heating and cooling cycles. This thermomechanical principle of operation is described in detail. Physical hydrogel samples are prepared as a disc-shaped gels (200 μm thick and 1 mm diameter) and placed between an on-chip heater and sensor devices. The sol-gel transition temperature of gelatin solution at various concentrations, used as a model physical hydrogel, shows less than 3% deviation from in-depth rheological results...
2017: PloS One
https://www.readbyqxmd.com/read/28537445/ultraviolet-induced-surface-grafting-of-octafluoropentyl-methacrylate-on-polyether-ether-ketone-for-inducing-antibiofilm-properties
#14
Parisa Amdjadi, Hanieh Nojehdehian, Farhood Najafi, Amir Ghasemi, Massoud Seifi, Erfan Dashtimoghadam, Farahnaz Fahimipour, Lobat Tayebi
Since octafluoropentyl methacrylate is an antifouling polymer, surface modification of polyether ether ketone with octafluoropentyl methacrylate is a practical approach to obtaining anti-biofilm biocompatible devices. In the current study, the surface treatment of polyether ether ketone by the use of ultraviolet irradiation, so as to graft (octafluoropentyl methacrylate) polymer chains, was initially implemented and then investigated. The Fourier-transform infrared and nuclear magnetic resonance spectra corroborated the appearance of new signals associated with the fluoroacrylate group...
January 1, 2017: Journal of Biomaterials Applications
https://www.readbyqxmd.com/read/28531651/synthesis-and-characterization-of-au-nps-supported-on-carbon-nanotubes-application-for-the-ultrasound-assisted-removal-of-radioactive-uo2-2-ions-following-complexation-with-arsenazo-iii-spectrophotometric-detection-optimization-isotherm-and-kinetic-study
#15
Mohammad Hassan Omidi, Farshid Nasiri Azad, Mehrorang Ghaedi, Arash Asfaram, Mohammad Hossein Ahmadi Azqhandi, Lobat Tayebi
The present study devoted to description of efficient removal of radioactive UO2(2+) ions (U(IV)) via complexation with Arsenazo III (ARS III) accelerated by ultrasound-assisted adsorption onto the Au-NPs supported on carbon nanotubes (Au-NPs-CNTs), which were characterized by conventional techniques such as FESEM, EDS and XRD. Central composite design (CCD) employed to model contribution of parameters viz. pH (2.5-8.5), adsorbent mass (5-25mg), UO2(2+) concentration (5-25mgL(-1)) and sonication time (1-5min) onto response...
May 13, 2017: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/28393586/evaluation-of-glycated-albumin-ga-and-ga-hba1c-ratio-for-diagnosis-of-diabetes-and-glycemic-control-a-comprehensive-review
#16
REVIEW
Sara Yazdanpanah, Mohammad Rabiee, Mohammadreza Tahriri, Mojgan Abdolrahim, Asadollah Rajab, Hossein E Jazayeri, Lobat Tayebi
Diabetes Mellitus (DM) is a group of metabolic diseases characterized by chronic high blood glucose concentrations (hyperglycemia). When it is left untreated or improperly managed, it can lead to acute complications including diabetic ketoacidosis and non-ketotic hyperosmolar coma. In addition, possible long-term complications include impotence, nerve damage, stroke, chronic kidney failure, cardiovascular disease, foot ulcers, and retinopathy. Historically, universal methods to measure glycemic control for the diagnosis of diabetes included fasting plasma glucose level (FPG), 2-h plasma glucose (2HP), and random plasma glucose...
June 2017: Critical Reviews in Clinical Laboratory Sciences
https://www.readbyqxmd.com/read/28006045/digital-holographic-microscopy-of-phase-separation-in-multicomponent-lipid-membranes
#17
Vahideh Farzam Rad, Ali-Reza Moradi, Ahmad Darudi, Lobat Tayebi
Lateral in-homogeneities in lipid compositions cause microdomains formation and change in the physical properties of biological membranes. With the presence of cholesterol and mixed species of lipids, phospholipid membranes segregate into lateral domains of liquid-ordered and liquid-disordered phases. Coupling of two-dimensional intralayer phase separations and interlayer liquid-crystalline ordering in multicomponent membranes has been previously demonstrated. By the use of digital holographic microscopy (DHMicroscopy), we quantitatively analyzed the volumetric dynamical behavior of such membranes...
December 1, 2016: Journal of Biomedical Optics
https://www.readbyqxmd.com/read/27987682/porous-magnesium-based-scaffolds-for-tissue-engineering
#18
REVIEW
Mostafa Yazdimamaghani, Mehdi Razavi, Daryoosh Vashaee, Keyvan Moharamzadeh, Aldo R Boccaccini, Lobat Tayebi
Significant amount of research efforts have been dedicated to the development of scaffolds for tissue engineering. Although at present most of the studies are focused on non-load bearing scaffolds, many scaffolds have also been investigated for hard tissue repair. In particular, metallic scaffolds are being studied for hard tissue engineering due to their suitable mechanical properties. Several biocompatible metallic materials such as stainless steels, cobalt alloys, titanium alloys, tantalum, nitinol and magnesium alloys have been commonly employed as implants in orthopedic and dental treatments...
February 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/27956150/a-novel-electrochemical-biosensor-based-on-fe3o4-nanoparticles-polyvinyl-alcohol-composite-for-sensitive-detection-of-glucose
#19
Niuosha Sanaeifar, Mohammad Rabiee, Mojgan Abdolrahim, Mohammadreza Tahriri, Daryoosh Vashaee, Lobat Tayebi
In this research, a new electrochemical biosensor was constructed for the glucose detection. Iron oxide nanoparticles (Fe3O4) were synthesized through co-precipitation method. Polyvinyl alcohol-Fe3O4 nanocomposite was prepared by dispersing synthesized nanoparticles in the polyvinyl alcohol (PVA) solution. Glucose oxidase (GOx) was immobilized on the PVA-Fe3O4 nanocomposite via physical adsorption. The mixture of PVA, Fe3O4 nanoparticles and GOx was drop cast on a tin (Sn) electrode surface (GOx/PVA-Fe3O4/Sn)...
February 15, 2017: Analytical Biochemistry
https://www.readbyqxmd.com/read/27826144/screening-of-nci-dtp-library-to-identify-new-drug-candidates-for-borrelia-burgdorferi
#20
Venkata Raveendra Pothineni, Dhananjay Wagh, Mustafeez Mujtaba Babar, Mohammed Inayathullah, R Edward Watts, Kwang-Min Kim, Mansi B Parekh, Abhijit Achyut Gurjarpadhye, David Solow-Cordero, Lobat Tayebi, Jayakumar Rajadas
No abstract text is available yet for this article.
March 2017: Journal of Antibiotics
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