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Saeed Heidari

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https://www.readbyqxmd.com/read/27660722/evaluation-of-the-immunogenicity-of-diphtheria-toxoid-conjugated-to-salmonella-typhimurium-derived-ops-in-a-mouse-model-a-potential-vaccine-candidate-against-salmonellosis
#1
Vahid Amini, Hossein Kazemian, Jalil Kardan Yamchi, Seifu Gizaw Feyisa, Saeed Aslani, Aref Shavalipour, Hamidreza Houri, Mohammadneshvan Hoorijani, Mehrdad Halaji, Hamid Heidari
BACKGROUND: Salmonella enterica serovar Typhimurium (S. Typhimurium) causes gastroenteritis in humans and paratyphoid disease in some animals. Given the emergence of antibiotic resistance, vaccines are more effective than chemotherapy in disease control. OBJECTIVES: The aim of this experimental study was to evaluate the immunogenicity of diphtheria toxoid (DT) conjugated with S. Typhimurium -derived OPS (O side chain isolation) in mice to determine its potential as a vaccine candidate against salmonellosis...
July 2016: Iranian Red Crescent Medical Journal
https://www.readbyqxmd.com/read/27652243/the-prevalence-of-pathologic-tooth-migration-with-respect-to-the-severity-of-periodontitis
#2
Hooman Khorshidi, Mohammad R Moaddeli, Ali Golkari, Heshmatollah Heidari, Saeed Raoofi
AIM: Pathologic tooth migration (PTM) has been defined as tooth displacement that occurs when the balance among the factors that maintain physiologic tooth position is disturbed by periodontal disease. The aim of this cross-sectional epidemiological study was to determine the prevalence of pathologic tooth migration among patients with periodontitis. MATERIALS AND METHODS: Recorded documents of 370 patients (72.4% females, 27.6% males) within the age range of 17 to 70 years (mean 37...
August 2016: Journal of International Society of Preventive & Community Dentistry
https://www.readbyqxmd.com/read/27458512/synthesis-and-evaluation-of-multi-wall-carbon-nanotube-paclitaxel-complex-as-an-anti-cancer-agent
#3
Fariba Ghasemvand, Esmaeil Biazar, Sara Tavakolifard, Mohammad Khaledian, Saeid Rahmanzadeh, Daruosh Momenzadeh, Roshanak Afroosheh, Faezeh Zarkalami, Marjan Shabannezhad, Saeed Hesami Tackallou, Nilofar Massoudi, Saeed Heidari Keshel
AIM: The aim of this study was to design multi-walled carbon nanotubes (MWCNTs) loaded with paclitaxel (PTX) anti-cancer drug and investigate its anti-cancerous efficacy of human gastric cancer. BACKGROUND: Carbon nanotubes (CNTs) represent a novel nano-materials applied in various fields such as drug delivery due to their unique chemical properties and high drug loading. PATIENTS AND METHODS: In this study, multi-walled carbon nanotubes (MWCNTs) pre-functionalized covalently with a paclitaxel (PTX) as an anti-cancer drug and evaluated by different analyses including, scanning electron microscope (SEM), particle size analyzer and cellular analyses...
2016: Gastroenterology and Hepatology From Bed to Bench
https://www.readbyqxmd.com/read/27433816/the-evaluation-of-alteration-of-elam-1-expression-in-the-endometriosis-patients
#4
Hoda Bahrami, Reza Roozafzoon, Zinat Ghanbari, Neda Jegargooshe, Parvaneh Jafari, Mohammad Nazari, Saeed Heidari-Keshel
BACKGROUND: As a definition, Endometriosis is a commonly encountered gynecological disease; as endometrial glandular and stromal cells existing in the outside of the uterus. In spite of several studies on endometriosis, its molecular mechanism and pathogenesis nevertheless have been not completely illuminated. Role of ELAM-1 gene in mediating the adhesion of tumor cells to endothelial cells by binding to ELAM-1 ligands expressed by eosinophils, neutrophils, monocytes, natural killer cell effectors T-lymphocyte cell, and cancer (progenitor/stem) cells is well studied...
July 19, 2016: Minerva Ginecologica
https://www.readbyqxmd.com/read/27390687/degarelix-for-the-treatment-of-advanced-prostate-cancer-compared-with-gnrh-agonists-a-systematic-review-and-meta-analysis
#5
Seyed Alireza Hosseini, Fatemeh Rajabi, Ali Akbari Sari, Mohsen Ayati, Saeed Heidari, Fawzieh Ghamary
BACKGROUND: Hormone therapy is currently the mainstay in the management of locally advanced and metastatic prostate cancer. We performed a systematic review to compare safety, efficacy and effectiveness of degarelix, a new gonadotropin-releasing hormone (GnRH) antagonist (blocker), versus gonadotropin-releasing hormone (GnRH) agonists. METHODS: MEDLINE, Web of Science and the Cochrane library were searched to identify all of the published Randomized Controlled Trials (RCTs) that used degarelix versus gonadotropin-releasing hormone agonists with or without anti-androgen therapy for the treatment of prostate cancer...
2016: Medical Journal of the Islamic Republic of Iran
https://www.readbyqxmd.com/read/27302429/physical-activity-status-and-related-factors-among-middle-aged-women-in-west-of-iran-hamadan-a-cross-sectional-study
#6
Shohreh Emdadi, Seyed Mohammad Mehdi Hazavehei, Alireza Soltanian, Saeed Bashirian, Rashid Heidari Moghadam
Physical inactivity is a major health problem in developing countries. Regular Physical Activity (RPA) can reduce the risk of many diseases such as cardiovascular disease, diabetes, and obesity that are prevalent in middle and old ages specifically in women. The (RPA) status among middle-aged Iranian women is not well known. The purpose of this study was to investigate the physical activity status and related factors among middle-aged women in Hamadan, a city in western Iran. The participants of this cross-sectional study were comprised of 866 middle-aged women in Hamadan who were selected using a proportional stratified random sampling method in 2015...
1, 2016: Global Journal of Health Science
https://www.readbyqxmd.com/read/27293055/a-novel-nonsense-mutation-in-exon-5-of-kind1-gene-in-an-iranian-family-with-kindler-syndrome
#7
Mohammad Mehdi Heidari, Mehri Khatami, Saeed Kargar, Mojdeh Azari, Hassan Hoseinzadeh, Hamedeh Fallah
BACKGROUND: Kindler syndrome (KS) is an autosomal recessive skin disease characterized by actual blistering, photosensitivity and a progressive poikiloderma. The disorder results from rare mutations in the KIND1 gene. This gene contains 15 exons and expresses two kindlin-1 isoforms. OBJECTIVE: The aim of this investigation was to analyze mutations in the exons 1 to 15 of KIND1 gene in an Iranian family clinically affected with Kindler syndrome. METHODS: The mutations analysis of 15 coding exons of KIND1 gene was performed with PCR-SSCP and direct sequencing in 14 subjects from one Iranian family clinically affected with Kindler syndrome...
June 2016: Archives of Iranian Medicine
https://www.readbyqxmd.com/read/26962521/the-effect-of-oral-tizanidine-on-postoperative-pain-relief-after-elective-laparoscopic-cholecystectomy
#8
Reihanak Talakoub, Saeed Abbasi, Elham Maghami, Sayyed Morteza Heidari Tabaei Zavareh
BACKGROUND: Cholecystectomy is considered as the most important and relatively common postoperative pain control often begins in recovery room by using systemic narcotics that may have some side effects. The aim of this study is to evaluate the effect of premedication with oral tizanidine on pain relief after elective laparoscopic cholecystectomy. MATERIALS AND METHODS: In this double-blinded clinical trial, 70 adults of American Society of Anesthesiologist physiologic state 1 and 2 scheduled for elective laparoscopic cholecystectomy under general anesthesia were studied and randomly divided in two study and control groups...
2016: Advanced Biomedical Research
https://www.readbyqxmd.com/read/26921746/renin-angiotensin-system-blockage-for-reduction-of-plasma-adiponectin-level-in-maintenance-hemodialysis-patients-a-randomized-controlled-trial
#9
Saeed Mardani, Maryam Heidari, Hamid Nasri
INTRODUCTION: Plasma adiponectin level is markedly in-creased among patients on hemodialysis. This investigation aimed to evaluate the relationship between renin-angiotensin system blockade and serum adiponectin concentration in nondiabetic patients on hemodialysis. MATERIALS AND METHODS: This randomized double-blind controlled trial was conducted on a group of nondiabetic patients on regular hemodialysis. The first group received losartan, 12.5 mg twice per day for the 1st week, 25 mg twice per day during the 2nd week, and 75 mg/d from the 3rd week to the end of the 16th week...
March 2016: Iranian Journal of Kidney Diseases
https://www.readbyqxmd.com/read/26837778/electrospun-mat-with-eyelid-fat-derived-stem-cells-as-a-scaffold-for-ocular-epithelial-regeneration
#10
Daruosh Momenzadeh, Alireza Baradaran-Rafii, Saeed Heidari Keshel, Maryam Ebrahimi, Esmaeil Biazar
The aim of this study was to develop nanofibrous gelatin substrates for eyelid fat stem cell (EFSC) expansion that can serve as a potential alternative substrate to replace human amniotic membrane. Biocompatibility results indicated that all substrates were highly biocompatible, as EFSCs could favorably attach and proliferate on the nanofibrous surfaces. Microscopic figures showed that the EFSC were firmly anchored to the substrates and were able to retain a normal stem cell phenotype. Immunocytochemistry (ICC) and real time-PCR results revealed change in the expression profile of EFSCs grown on nanofibrous substrates when compared to those grown on control in epithelial induction condition...
February 2, 2016: Artificial Cells, Nanomedicine, and Biotechnology
https://www.readbyqxmd.com/read/26721797/the-comparative-efficacy-of-tyloxapol-versus-pentoxifylline-against-induced-acute-phase-response-in-an-ovine-experimental-endotoxemia-model
#11
Aliasghar Chalmeh, Alireza Rahmani Shahraki, Seyed Mohammad Mehdi Heidari, Khalil Badiei, Mehrdad Pourjafar, Saeed Nazifi, Mohammad Javad Zamiri
The effective treatments of endotoxemia are necessary to prevent high mortality rates. Hence, the present study was performed to clarify the antiendotoxic effects of tyloxapol and pentoxifylline in experimentally induced endotoxemia in sheep. Thirty clinically healthy 1-year-old Iranian fat-tailed ewes were randomly divided into six equal experimental (n = 5) groups, comprising Negative and Positive control, Tyloxapol 1, Tyloxapol 2, Pentoxifylline 1 and Pentoxifylline 2. Phenol extracted lipopolysaccharide from Escherichia coli serotype O55:B5 was infused at 2 µg/kg intravenously...
February 2016: Inflammopharmacology
https://www.readbyqxmd.com/read/26324020/oriented-nanofibrous-silk-as-a-natural-scaffold-for-ocular-epithelial-regeneration
#12
COMPARATIVE STUDY
Esmaeil Biazar, Alireza Baradaran-Rafii, Saeed Heidari-keshel, Sara Tavakolifard
The aim of this study was to develop nanofibrous silk substrates for limbal stem cell expansion that can serve as a potential alternative substrate to replace human amniotic membrane. The human limbal stem cell was used to evaluate the biocompatibility of substrates (random and oriented nanofibrous mats, and human amniotic membrane) based on their phenotypic profile, viability, proliferation, and attachment ability. Biocompatibility results indicated that all substrates were highly biocompatible, as limbal stem cells could favorably attach and proliferate on the nanofibrous surfaces...
2015: Journal of Biomaterials Science. Polymer Edition
https://www.readbyqxmd.com/read/26157570/an-overview-on-the-comprehensive-program-on-prevention-and-control-of-high-risk-behaviors-in-7-18-year-old-individuals-in-isfahan-iran
#13
Kamal Heidari, Ziba Farajzadegan, Rezvan Pashmi, Saeed Bagheri, Seyyed Azim Fatemi, Roya Kelishadi
No abstract text is available yet for this article.
December 2014: International Journal of Preventive Medicine
https://www.readbyqxmd.com/read/26157563/body-mass-index-weight-for-age-and-stature-for-age-indices-in-iranian-school-children-in-relation-to-weight-and-growth-disorders-a-population-based-survey
#14
Sakineh Jafari, Maryam Fouladgar, Marjan Manouchehri Naeeni, Maryam Fakhri, Sayed Azim Fatemi, Kamal Heidari, Saeed Bagheri
BACKGROUND: Present study aimed to evaluate the prevalence of grades of nutritional status comprising underweight, normal weight, overweight, and obesity as well as other measurable anthropometric indicators of body mass index (BMI) in regard to gender, educational level, and living area among students settled in Isfahan province. METHODS: This cross-sectional study was conducted on a sample of 4700 individuals (2349 females and 2351 males) being from 9 to 15 years old, while they were students of either primary school or junior high school...
December 2014: International Journal of Preventive Medicine
https://www.readbyqxmd.com/read/26157562/knowledge-and-practice-of-junior-and-senior-high-school-students-regarding-violent-behaviors-in-isfahan-province
#15
Razieh Omidi, Kamal Heidari, Arash Ramezani, Maryam Amini, Shiva Kamrooz, Ziba Farajzadegan, Rezvan Pashmi, Seyyed Azim Fatemi, Saeed Bagheri, Abolfazl Salimi, Anahita Babak
BACKGROUND: Considering the importance of anger, aggression, violence and other misbehaviours in schoolchildren education, the present study was conducted to evaluate the knowledge and practice of students in Isfahan province regarding violence, in order to figure out the required interventions for violence-reduction. METHODS: In a survey during 2008-2009, 5500 junior and senior high school students of Isfahan province were assessed in a multistage sampling process to determine their level of knowledge about various types of violent behaviors, causes of violence, its consequences, and preventive behaviors...
December 2014: International Journal of Preventive Medicine
https://www.readbyqxmd.com/read/26140614/human-unrestricted-somatic-stem-cells-loaded-in-nanofibrous-pcl-scaffold-and-their-healing-effect-on-skin-defects
#16
Hoda Bahrami, Saeed Heidari Keshel, Aliakbar Jafari Chari, Esmaeil Biazar
Unrestricted somatic stem cells (USSCs) loaded in nanofibrous polycaprolactone (PCL) scaffolds can be used for skin regeneration when grafted onto full-thickness skin defects of rats. Nanofibrous PCL scaffolds were designed by the electrospinning method and crosslinked with laminin protein. Afterwards, the scaffolds were evaluated by scanning electron microscopy, and physical and mechanical assays. In this study, nanofibrous PCL scaffolds loaded with USSCs were grafted onto the skin defects. The wounds were subsequently investigated 21 days after grafting...
September 2016: Artificial Cells, Nanomedicine, and Biotechnology
https://www.readbyqxmd.com/read/25972860/dissection-of-the-cis-2-decenoic-acid-signaling-network-in-pseudomonas-aeruginosa-using-microarray-technique
#17
Azadeh Rahmani-Badi, Shayesteh Sepehr, Hossein Fallahi, Saeed Heidari-Keshel
Many bacterial pathogens use quorum-sensing (QS) signaling to regulate the expression of factors contributing to virulence and persistence. Bacteria produce signals of different chemical classes. The signal molecule, known as diffusible signal factor (DSF), is a cis-unsaturated fatty acid that was first described in the plant pathogen Xanthomonas campestris. Previous works have shown that human pathogen, Pseudomonas aeruginosa, also synthesizes a structurally related molecule, characterized as cis-2-decenoic acid (C10: Δ(2), CDA) that induces biofilm dispersal by multiple types of bacteria...
2015: Frontiers in Microbiology
https://www.readbyqxmd.com/read/25919283/prognostic-significance-of-matrix-metalloproteinase-7-in-gastric-cancer-survival-a-meta-analysis
#18
Saeed Soleyman-Jahi, Saharnaz Nedjat, Afshin Abdirad, Niloofar Hoorshad, Reza Heidari, Kazem Zendehdel
The prognostic role of matrix metalloproteinase-7 in gastric cancer survival has been widely evaluated. However, the results are controversial. We aimed to set up a meta-analysis to reach a conclusion on the prognostic significance of metalloproteinase-7 in gastric cancer survival as well as its association with clinicopathological parameters. We searched popular databases from 1988 until October 2014 to gather eligible peer-reviewed papers addressing the prognostic effect of matrix metalloproteinase-7 in gastric cancer patients' survival...
2014: PloS One
https://www.readbyqxmd.com/read/25897888/cellular-response-of-limbal-stem-cells-on-polycaprolactone-nanofibrous-scaffolds-for-ocular-epithelial-regeneration
#19
Alireza Baradaran-Rafii, Esmaeil Biazar, Saeed Heidari-keshel
PURPOSE: The aim of this study was to develop nanofibrous polycaprolactone (PCL) substrate for limbal stem cell (LSC) expansion that can serve as a potential alternative substrate to replace human amniotic membrane (AM). MATERIALS AND METHODS: The human limbus stem cell was used to evaluate the biocompatibility of substrates (nanofibrous scaffold and, human AM) based on their phenotypic profile, viability, proliferation and attachment ability. RESULTS: Biocompatibility results indicated that the all substrates were highly biocompatible, as LSCs could favorably attach and proliferate on the nanofibrous surface...
2016: Current Eye Research
https://www.readbyqxmd.com/read/25847506/hyperoxia-induced-preconditioning-against-renal-ischemic-injury-is-mediated-by-reactive-oxygen-species-but-not-related-to-heat-shock-proteins-70-and-32
#20
COMPARATIVE STUDY
Hannaneh Wahhabaghai, Reza Heidari, Atefeh Zeinoddini, Saeed Soleyman-Jahi, Leila Golmanesh, Bahram Rasoulian, Hassan Akbari, Mohsen Foadoddoni, Mansour Esmailidehaj
OBJECTIVE: Pre-exposure of rats to normobaric hyperoxia (O2 ≥ 95%) may induce late preconditioning against renal ischemia-reperfusion (IR) injury. In this study we investigated probable mechanisms of IR injury such as the role of reactive oxygen species (ROS), renal antioxidant agents, and heat shock proteins (HSP) 32 and 70 during delayed hyperoxia-preconditioning (HO). METHODS: Fifty-two rats were divided into 7 groups: (A) IR, (B) HO + IR, (C) mercaptopropionyl glycine (MPG) + HO + IR, (D) MPG + IR, (E) HO + sham, (F) MPG + sham, and (G) sham...
June 2015: Surgery
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