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Saeed Heidari

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https://www.readbyqxmd.com/read/28638809/dual-peer-mentoring-program-for-undergraduate-medical-students-exploring-the-perceptions-of-mentors-and-mentees
#1
Parya Abdolalizadeh, Saeed Pourhassan, Roghayeh Gandomkar, Farrokh Heidari, Amir Ali Sohrabpour
Background: Despite the advantages of dual peer mentoring, there are a few reports of implementing and evaluating such programs for medical students. This study aimed at exploring the perceptions of mentors and mentees about the dual peer mentoring program for the first year undergraduate medical students of Tehran University of Medical Sciences. Methods: This qualitative study was conducted at the end of the first year of implementing the mentoring program. All mentees and mentors were invited to participate in focus group discussions...
2017: Medical Journal of the Islamic Republic of Iran
https://www.readbyqxmd.com/read/28540005/post-photorefractive-keratectomy-pain-and-corneal-sub-basal-nerve-density
#2
Masoumeh Mohebbi, Amin Rafat-Nejad, Seyed-Farzad Mohammadi, Kosar Asna-Ashari, Maryam Kasiri, Saeed Heidari-Keshel, Farshad Askarizadeh
PURPOSE: The perceived and reported pain of patients receiving photorefractive keratectomy (PRK) widely varies. We assessed the potential role of the subbasal nerve plexus density as a predictor of postoperative pain level. Consecutive patients scheduled to undergo PRK at the Refractive Surgery Clinic of Farabi Eye Hospital, Tehran, were approached. METHODS: Forty-nine myopic left eyes from 49 patients who consented to undergo scanning slit confocal microscopy assessments preoperatively were included...
April 2017: Journal of Ophthalmic & Vision Research
https://www.readbyqxmd.com/read/28532015/effect-of-sintering-temperature-rise-from-870-to-920%C3%A2-c-on-physicomechanical-and-biological-quality-of-nano-hydroxyapatite-an-explorative-multi-phase-experimental-in-vitro-vivo-study
#3
Ahad Khoshzaban, Vahid Rakhshan, Farhood Najafi, Leila Aghajanpour, Seyed Jafar Hashemian, Saeed Heidari Keshel, Ikuya Watanabe, Alireza Valanezhad, Tahereh Sadat Jafarzadeh Kashi
Hydroxyapatite (HA) is a proper scaffold for bone repair, however, it is not of excellent mechanical properties. Most previous studies on the effect of temperature increases were in vitro and had assessed merely improvements of HA's physicomechanical quality. This in vitro/vivo study investigated the effect of temperature increases from 870 to 920°C on physicomechanical and biological quality of Nano-HA. Forty experimentally produced HA disks sintered at 870 to 920°C were prepared (n=20×2). Disks were subjected to Vickers microindentation test (1 disk from each group divided into 4 quarters), Fourier transform infrared spectroscopy (1 disk), X-ray diffraction (XRD) [1 disk together with non-sintered HA], field emission scanning electron microscopy (FSEM, 1 disk from each group together with non-sintered HA), cell seeding and SEM assessment (2 disks), MTT assay over 4 different time periods (16 quadrants of 4 disks from each group), 6 one-thirds of 2 disks from each group for immunocytochemical (ICC) assay, and 8 disks from each group [as well as non-sintered HA] for the animal study (implantation in 4 sockets in 8 rabbits [32 specimens], histomorphometry, and computerized tomography) over two time periods...
August 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28512477/physical-properties-and-chemical-characterization-of-two-experimental-epoxy-resin-root-canal-sealers
#4
Hengameh Ashraf, Farhood Najafi, Soolmaz Heidari, Manijeh Mohammadian, Saeede Zadsirjan
INTRODUCTION: The aim of this in vitro study was to evaluate the setting time, flow, film thickness, solubility, radiopacity and characterization analysis of three epoxy resin based sealers including two experimental sealers and AH-26. METHODS AND MATERIALS: Five samples of each material were evaluated for setting time, flow, film thickness, solubility and radiopacity according to ISO 6876 Standard. Characterization of sealers was performed under the scanning electron microscopy (SEM), X-ray energy dispersive spectroscopy, X-ray diffraction (XRD) and Fourier transform infrared (FTIR) spectroscopy...
2017: Iranian Endodontic Journal
https://www.readbyqxmd.com/read/28497089/impact-of-oral-capsule-of-peganum-harmala-on-alleviating-urinary-symptoms-in-men-with-benign-prostatic-hyperplasia-a-randomized-clinical-trial
#5
Majid Shirani-Boroujeni, Saeed Heidari-Soureshjani, Zahra Keivani Hafshejani
Introduction: Benign prostatic hyperplasia (BPH) is considered as a major cause of lower urinary tract symptoms (LUTS) in older men and its most common sign is nocturia. Objectives: This study aimed to determine the effect of the seeds of Peganum harmala compared with tamsulosin on alleviating urinary symptoms in patients with BPH. Patients and Methods: In this single blind clinical trial study, 90 patients diagnosed with BPH and LUTS, based on international prostate standard survey (IPSS) were divided into three groups...
2017: Journal of Renal Injury Prevention
https://www.readbyqxmd.com/read/28483183/the-effect-of-transcutaneous-electrical-nerve-stimulation-of-sympathetic-ganglions-and-acupuncture-points-on-distal-blood-flow
#6
Fahimeh Kamali, Hossein Mirkhani, Ahmadreza Nematollahi, Saeed Heidari, Elahesadat Moosavi, Marzieh Mohamadi
Transcutaneous electrical nerve stimulation (TENS) is a widely-practiced method to increase blood flow in clinical practice. The best location for stimulation to achieve optimal blood flow has not yet been determined. We compared the effect of TENS application at sympathetic ganglions and acupuncture points on blood flow in the foot of healthy individuals. Seventy-five healthy individuals were randomly assigned to three groups. The first group received cutaneous electrical stimulation at the thoracolumbar sympathetic ganglions...
April 2017: Journal of Acupuncture and Meridian Studies
https://www.readbyqxmd.com/read/28392901/mutation-analysis-of-connexin-50-gene-among-iranian-families-with-autosomal-dominant-cataracts
#7
Masoumeh Mohebi, Saeed Chenari, Abolfazl Akbari, Fariba Ghassemi, Mehran Zarei-Ghanavati, Ghasem Fakhraie, Nahid Babaie, Mansour Heidari
OBJECTIVES: Childhood cataract is a genetically heterogeneous eye disorder that results in visual impairment. The aim of this study was to identify the genetic mutations of connexin 50 gene among Iranian families suffered from autosomal dominant congenital cataracts (ADCC). MATERIALS AND METHODS: Families, having at least two members with bilateral familial congenital cataract, were selected for the study. Probands were evaluated by detailed ophthalmologist's examination, and the pedigree analysis was performed...
March 2017: Iranian Journal of Basic Medical Sciences
https://www.readbyqxmd.com/read/28055030/prognostic-significance-of-preoperative-and-postoperative-plasma-levels-of-ghrelin-in-gastric-cancer-3-year-survival-study
#8
Saeed Soleyman-Jahi, Afshin Abdirad, Amir Afraz Fallah, Sevil Ghasemi, Fatemeh Sadeghi, Reza Heidari, Habibollah Mahmoodzadeh, Kazem Zendehdel
OBJECTIVES: We aimed to investigate prognostic effects of plasma levels of ghrelin before and after gastrectomy in gastric cancer (GC). METHODS: We followed 81 GC patients up to 3 years in this study. They were candidates for curative gastrectomy with or without neoadjuvant chemotherapy. Plasma levels of total and active ghrelins before and after the operation were assessed. Association of plasma levels of ghrelin with survival were assessed and adjusted for other potential prognostic factors using Cox regression analyses...
January 5, 2017: Clinical and Translational Gastroenterology
https://www.readbyqxmd.com/read/27981851/molecular-detection-of-aminoglycoside-modifying-enzyme-genes-in-acinetobacter-baumannii-clinical-isolates
#9
Mohsen Heidary, Alireza Salimi Chirani, Saeed Khoshnood, Gita Eslami, Seyyed Mohammad Atyabi, Habibollah Nazem, Mohammad Fazilati, Ali Hashemi, Saleh Soleimani
Acinetobacter baumannii is a major opportunistic pathogen in healthcare settings worldwide. In Iran, there are only few reports on the prevalence of aminoglycoside resistance genes among A. baumannii isolates. The aim of this study was to investigate the existence of aminoglycoside-modifying enzyme (AME) genes from A. baumannii strains collected at a university teaching hospital in Iran. One hundred A. baumannii strains were collected between 2014 and 2015 from hospitalized patients at Loghman Hakim Hospital, Tehran, Iran...
December 16, 2016: Acta Microbiologica et Immunologica Hungarica
https://www.readbyqxmd.com/read/27660722/evaluation-of-the-immunogenicity-of-diphtheria-toxoid-conjugated-to-salmonella-typhimurium-derived-ops-in-a-mouse-model-a-potential-vaccine-candidate-against-salmonellosis
#10
Vahid Amini, Hossein Kazemian, Jalil Kardan Yamchi, Seifu Gizaw Feyisa, Saeed Aslani, Aref Shavalipour, Hamidreza Houri, Mohammadneshvan Hoorijani, Mehrdad Halaji, Hamid Heidari
BACKGROUND: Salmonella enterica serovar Typhimurium (S. Typhimurium) causes gastroenteritis in humans and paratyphoid disease in some animals. Given the emergence of antibiotic resistance, vaccines are more effective than chemotherapy in disease control. OBJECTIVES: The aim of this experimental study was to evaluate the immunogenicity of diphtheria toxoid (DT) conjugated with S. Typhimurium -derived OPS (O side chain isolation) in mice to determine its potential as a vaccine candidate against salmonellosis...
July 2016: Iranian Red Crescent Medical Journal
https://www.readbyqxmd.com/read/27652243/the-prevalence-of-pathologic-tooth-migration-with-respect-to-the-severity-of-periodontitis
#11
Hooman Khorshidi, Mohammad R Moaddeli, Ali Golkari, Heshmatollah Heidari, Saeed Raoofi
AIM: Pathologic tooth migration (PTM) has been defined as tooth displacement that occurs when the balance among the factors that maintain physiologic tooth position is disturbed by periodontal disease. The aim of this cross-sectional epidemiological study was to determine the prevalence of pathologic tooth migration among patients with periodontitis. MATERIALS AND METHODS: Recorded documents of 370 patients (72.4% females, 27.6% males) within the age range of 17 to 70 years (mean 37...
August 2016: Journal of International Society of Preventive & Community Dentistry
https://www.readbyqxmd.com/read/27458512/synthesis-and-evaluation-of-multi-wall-carbon-nanotube-paclitaxel-complex-as-an-anti-cancer-agent
#12
Fariba Ghasemvand, Esmaeil Biazar, Sara Tavakolifard, Mohammad Khaledian, Saeid Rahmanzadeh, Daruosh Momenzadeh, Roshanak Afroosheh, Faezeh Zarkalami, Marjan Shabannezhad, Saeed Hesami Tackallou, Nilofar Massoudi, Saeed Heidari Keshel
AIM: The aim of this study was to design multi-walled carbon nanotubes (MWCNTs) loaded with paclitaxel (PTX) anti-cancer drug and investigate its anti-cancerous efficacy of human gastric cancer. BACKGROUND: Carbon nanotubes (CNTs) represent a novel nano-materials applied in various fields such as drug delivery due to their unique chemical properties and high drug loading. PATIENTS AND METHODS: In this study, multi-walled carbon nanotubes (MWCNTs) pre-functionalized covalently with a paclitaxel (PTX) as an anti-cancer drug and evaluated by different analyses including, scanning electron microscope (SEM), particle size analyzer and cellular analyses...
2016: Gastroenterology and Hepatology From Bed to Bench
https://www.readbyqxmd.com/read/27433816/evaluation-of-elam-1-expression-alteration-in-endometriosis
#13
Hoda Bahrami, Reza Roozafzoon, Zinat Ghanbari, Neda Jegargooshe, Parvaneh Jafari, Mohammad Nazari, Saeed Heidari-Keshel
BACKGROUND: Endometriosis is a commonly-encountered gynecological disease characterized by the presence of endometrial glandular and stromal cells outside of the uterus. Several studies have been conducted on endometriosis, however its molecular mechanism and pathogenesis are still not completely clear. The role of ELAM-1 gene in mediating the adhesion of tumor cells to endothelial cells by binding to ELAM-1 ligands expressed by eosinophils, neutrophils, monocytes, natural killer cell effectors, T lymphocyte cells, and cancer (progenitor/stem) cells is well studied...
April 2017: Minerva Ginecologica
https://www.readbyqxmd.com/read/27390687/degarelix-for-the-treatment-of-advanced-prostate-cancer-compared-with-gnrh-agonists-a-systematic-review-and-meta-analysis
#14
Seyed Alireza Hosseini, Fatemeh Rajabi, Ali Akbari Sari, Mohsen Ayati, Saeed Heidari, Fawzieh Ghamary
BACKGROUND: Hormone therapy is currently the mainstay in the management of locally advanced and metastatic prostate cancer. We performed a systematic review to compare safety, efficacy and effectiveness of degarelix, a new gonadotropin-releasing hormone (GnRH) antagonist (blocker), versus gonadotropin-releasing hormone (GnRH) agonists. METHODS: MEDLINE, Web of Science and the Cochrane library were searched to identify all of the published Randomized Controlled Trials (RCTs) that used degarelix versus gonadotropin-releasing hormone agonists with or without anti-androgen therapy for the treatment of prostate cancer...
2016: Medical Journal of the Islamic Republic of Iran
https://www.readbyqxmd.com/read/27302429/physical-activity-status-and-related-factors-among-middle-aged-women-in-west-of-iran-hamadan-a-cross-sectional-study
#15
Shohreh Emdadi, Seyed Mohammad Mehdi Hazavehei, Alireza Soltanian, Saeed Bashirian, Rashid Heidari Moghadam
Physical inactivity is a major health problem in developing countries. Regular Physical Activity (RPA) can reduce the risk of many diseases such as cardiovascular disease, diabetes, and obesity that are prevalent in middle and old ages specifically in women. The (RPA) status among middle-aged Iranian women is not well known. The purpose of this study was to investigate the physical activity status and related factors among middle-aged women in Hamadan, a city in western Iran. The participants of this cross-sectional study were comprised of 866 middle-aged women in Hamadan who were selected using a proportional stratified random sampling method in 2015...
October 1, 2016: Global Journal of Health Science
https://www.readbyqxmd.com/read/27293055/a-novel-nonsense-mutation-in-exon-5-of-kind1-gene-in-an-iranian-family-with-kindler-syndrome
#16
Mohammad Mehdi Heidari, Mehri Khatami, Saeed Kargar, Mojdeh Azari, Hassan Hoseinzadeh, Hamedeh Fallah
BACKGROUND: Kindler syndrome (KS) is an autosomal recessive skin disease characterized by actual blistering, photosensitivity and a progressive poikiloderma. The disorder results from rare mutations in the KIND1 gene. This gene contains 15 exons and expresses two kindlin-1 isoforms. OBJECTIVE: The aim of this investigation was to analyze mutations in the exons 1 to 15 of KIND1 gene in an Iranian family clinically affected with Kindler syndrome. METHODS: The mutations analysis of 15 coding exons of KIND1 gene was performed with PCR-SSCP and direct sequencing in 14 subjects from one Iranian family clinically affected with Kindler syndrome...
June 2016: Archives of Iranian Medicine
https://www.readbyqxmd.com/read/26962521/the-effect-of-oral-tizanidine-on-postoperative-pain-relief-after-elective-laparoscopic-cholecystectomy
#17
Reihanak Talakoub, Saeed Abbasi, Elham Maghami, Sayyed Morteza Heidari Tabaei Zavareh
BACKGROUND: Cholecystectomy is considered as the most important and relatively common postoperative pain control often begins in recovery room by using systemic narcotics that may have some side effects. The aim of this study is to evaluate the effect of premedication with oral tizanidine on pain relief after elective laparoscopic cholecystectomy. MATERIALS AND METHODS: In this double-blinded clinical trial, 70 adults of American Society of Anesthesiologist physiologic state 1 and 2 scheduled for elective laparoscopic cholecystectomy under general anesthesia were studied and randomly divided in two study and control groups...
2016: Advanced Biomedical Research
https://www.readbyqxmd.com/read/26921746/renin-angiotensin-system-blockage-for-reduction-of-plasma-adiponectin-level-in-maintenance-hemodialysis-patients-a-randomized-controlled-trial
#18
RANDOMIZED CONTROLLED TRIAL
Saeed Mardani, Maryam Heidari, Hamid Nasri
INTRODUCTION: Plasma adiponectin level is markedly in-creased among patients on hemodialysis. This investigation aimed to evaluate the relationship between renin-angiotensin system blockade and serum adiponectin concentration in nondiabetic patients on hemodialysis. MATERIALS AND METHODS: This randomized double-blind controlled trial was conducted on a group of nondiabetic patients on regular hemodialysis. The first group received losartan, 12.5 mg twice per day for the 1st week, 25 mg twice per day during the 2nd week, and 75 mg/d from the 3rd week to the end of the 16th week...
March 2016: Iranian Journal of Kidney Diseases
https://www.readbyqxmd.com/read/26837778/electrospun-mat-with-eyelid-fat-derived-stem-cells-as-a-scaffold-for-ocular-epithelial-regeneration
#19
Daruosh Momenzadeh, Alireza Baradaran-Rafii, Saeed Heidari Keshel, Maryam Ebrahimi, Esmaeil Biazar
The aim of this study was to develop nanofibrous gelatin substrates for eyelid fat stem cell (EFSC) expansion that can serve as a potential alternative substrate to replace human amniotic membrane. Biocompatibility results indicated that all substrates were highly biocompatible, as EFSCs could favorably attach and proliferate on the nanofibrous surfaces. Microscopic figures showed that the EFSC were firmly anchored to the substrates and were able to retain a normal stem cell phenotype. Immunocytochemistry (ICC) and real time-PCR results revealed change in the expression profile of EFSCs grown on nanofibrous substrates when compared to those grown on control in epithelial induction condition...
February 2017: Artificial Cells, Nanomedicine, and Biotechnology
https://www.readbyqxmd.com/read/26721797/the-comparative-efficacy-of-tyloxapol-versus-pentoxifylline-against-induced-acute-phase-response-in-an-ovine-experimental-endotoxemia-model
#20
COMPARATIVE STUDY
Aliasghar Chalmeh, Alireza Rahmani Shahraki, Seyed Mohammad Mehdi Heidari, Khalil Badiei, Mehrdad Pourjafar, Saeed Nazifi, Mohammad Javad Zamiri
The effective treatments of endotoxemia are necessary to prevent high mortality rates. Hence, the present study was performed to clarify the antiendotoxic effects of tyloxapol and pentoxifylline in experimentally induced endotoxemia in sheep. Thirty clinically healthy 1-year-old Iranian fat-tailed ewes were randomly divided into six equal experimental (n = 5) groups, comprising Negative and Positive control, Tyloxapol 1, Tyloxapol 2, Pentoxifylline 1 and Pentoxifylline 2. Phenol extracted lipopolysaccharide from Escherichia coli serotype O55:B5 was infused at 2 µg/kg intravenously...
February 2016: Inflammopharmacology
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