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https://www.readbyqxmd.com/read/27255958/the-amyloid-cascade-hypothesis-are-we-poised-for-success-or-failure
#1
Eric Karran, Bart De Strooper
The first description of Alzheimer's disease (AD) was made in 1907 by Alois Alzheimer (Allgemeine Zeitschrift fur Psyciatrie und Psychisch-Gerichtliche Medizin 64, 3, 1907), although other contemporary physicians had made similar, and rather more complete, assessments of the neuropathological changes present in the AD brain (Fischer, Monatsschr Psychiat Neurol 22, 17, 1907). Our knowledge of AD has increased dramatically and continues to accelerate. This year is 25 years after the publication of a series of papers that, in various ways, articulated the amyloid cascade hypothesis (ACH) for AD (Beyreuther and Masters, Brain Pathol 1, 241-251, 1991; Hardy and Allsop, Trends Pharmacol Sci 12, 383-388, 1991; Selkoe, Neuron 6, 487-498, 1991; Hardy and Higgins, Science 256, 184-185, 1992)...
June 3, 2016: Journal of Neurochemistry
https://www.readbyqxmd.com/read/608814/community-psyciatry-in-nigeria-the-current-status
#2
A Boroffka, M O Olatawura
Over a period of 50 months, 512 psychiatric patients were treated in the Aro Village therapeutic community. The majority of those admitted (94.1%) had symptoms of psychosis. By the end of three months 57.8% had been discharged, while 88.9% were discharged by the end of five months. Of these, 70.3% were judged fit to return to their work. The relatives of patients as well as the villagers were involved in the treatment programme. The advantages of this method, are discussed, as well as the implications for the future of the programme of the loosening of traditional family ties resulting from rapid urbanisation...
1977: International Journal of Social Psychiatry
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