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https://www.readbyqxmd.com/read/29200188/the-measurable-benefits-of-a-workplace-wellness-program-in-canada-results-after-one-year
#1
Ilka Lowensteyn, Violette Berberian, Patrick Belisle, Deborah DaCosta, Lawrence Joseph, Steven A Grover
OBJECTIVE: Evaluate the impact of an employee wellness program in Canada. METHODS: A comprehensive program including web-based lifestyle challenges was evaluated with annual health screenings. RESULTS: Among 730 eligible employees, 688 (94%) registered for the program, 571 (78%) completed a health screening at baseline, and 314 (43%) at 1 year. Most (66%) employees tracked their activity for more than 6 weeks. At one year follow-up, there were significant clinical improvements in systolic blood pressure -3...
December 1, 2017: Journal of Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/29197617/3-d-motion-capture-for-long-term-tracking-of-spontaneous-locomotor-behaviors-and-circadian-sleep-wake-rhythms-in-mouse
#2
Melissa Sourioux, Emma Bestaven, Etienne Guillaud, Sandrine Bertrand, Magali Cabanas, Lea Milan, Willy Mayo, Maurice Garret, Jean-René Cazalets
BACKGROUND: Locomotor activity provides an index of an animal's behavioral state. Here, we report a reliable and cost-effective method that allows long-term (days to months) simultaneous tracking of locomotion in mouse cohorts (here consisting of 24 animals). NEW METHOD: The technique is based on a motion capture system used mainly for human movement study. A reflective marker was placed on the head of each mouse using a surgical procedure and labeled animals were returned to their individual home cages...
November 29, 2017: Journal of Neuroscience Methods
https://www.readbyqxmd.com/read/29192613/a-health-based-metric-for-evaluating-the-effectiveness-of-noise-barrier-mitigation-associated-with-transport-infrastructure-noise
#3
Geoffrey P Prendergast, Michael Staff
INTRODUCTION: This study examines the use of the number of night-time sleep disturbances as a health-based metric to assess the cost effectiveness of rail noise mitigation strategies for situations, wherein high-intensity noises dominate such as freight train pass-bys and wheel squeal. MATERIALS AND METHODS: Twenty residential properties adjacent to the existing and proposed rail tracks in a noise catchment area of the Epping to Thornleigh Third Track project were used as a case study...
March 2017: Noise & Health
https://www.readbyqxmd.com/read/29175999/modern-fertility-awareness-methods-wrist-wearables-capture-the-changes-of-temperature-associated-with-the-menstrual-cycle
#4
Mohaned Shilaih, Brianna M Goodale, Lisa Falco, Florian Kübler, Valerie De Clerck, Brigitte Leeners
Core and peripheral body temperatures are affected by changes in reproductive hormones during the menstrual cycle. Women worldwide use the basal body temperature (BBT) method to aid and prevent conception. However, prior research suggests taking one's daily temperature can prove inconvenient and subject to environmental factors. We investigate whether a more automatic, non-invasive temperature measurement system can detect changes in temperature across the menstrual cycle. We examined how wrist-skin temperature (WST), measured with wearable sensors, correlates with urinary tests of ovulation and may serve as a new method of fertility tracking...
November 24, 2017: Bioscience Reports
https://www.readbyqxmd.com/read/29166387/effects-of-total-sleep-deprivation-on-divided-attention-performance
#5
Eric Chern-Pin Chua, Eric Fang, Joshua J Gooley
Dividing attention across two tasks performed simultaneously usually results in impaired performance on one or both tasks. Most studies have found no difference in the dual-task cost of dividing attention in rested and sleep-deprived states. We hypothesized that, for a divided attention task that is highly cognitively-demanding, performance would show greater impairment during exposure to sleep deprivation. A group of 30 healthy males aged 21-30 years was exposed to 40 h of continuous wakefulness in a laboratory setting...
2017: PloS One
https://www.readbyqxmd.com/read/29161270/tracking-urban-human-activity-from-mobile-phone-calling-patterns
#6
Daniel Monsivais, Asim Ghosh, Kunal Bhattacharya, Robin I M Dunbar, Kimmo Kaski
Timings of human activities are marked by circadian clocks which in turn are entrained to different environmental signals. In an urban environment the presence of artificial lighting and various social cues tend to disrupt the natural entrainment with the sunlight. However, it is not completely understood to what extent this is the case. Here we exploit the large-scale data analysis techniques to study the mobile phone calling activity of people in large cities to infer the dynamics of urban daily rhythms. From the calling patterns of about 1,000,000 users spread over different cities but lying inside the same time-zone, we show that the onset and termination of the calling activity synchronizes with the east-west progression of the sun...
November 2017: PLoS Computational Biology
https://www.readbyqxmd.com/read/29150872/predicting-the-onset-of-freezing-of-gait-a-longitudinal-study
#7
Kaylena A Ehgoetz Martens, Emily L Lukasik, Matthew J Georgiades, Moran Gilat, Julie M Hall, Courtney C Walton, Simon J G Lewis
BACKGROUND: Freezing of gait is a disabling symptom of Parkinson's disease that ultimately affects approximately 80% of patients, yet very little research has focused on predicting the onset of freezing of gait and tracking the longitudinal progression of symptoms prior to its onset. The objective of the current study was to examine longitudinal data spanning the transition period when patients with PD developed freezing of gait to identify symptoms that may precede freezing and create a prediction model that identifies those "at risk" for developing freezing of gait in the year to follow...
November 18, 2017: Movement Disorders: Official Journal of the Movement Disorder Society
https://www.readbyqxmd.com/read/29144168/the-effects-of-extended-nap-periods-on-cognitive-physiological-and-subjective-responses-under-simulated-night-shift-conditions
#8
Jonathan Davy, Matthias Göbel
Extended nap opportunities have been effective in maintaining alertness in the context of extended night shifts (+12 h). However, there is limited evidence of their efficacy during 8-h shifts. Thus, this study explored the effects of extended naps on cognitive, physiological and perceptual responses during four simulated, 8-h night shifts. In a laboratory setting, 32 participants were allocated to one of three conditions. All participants completed four consecutive, 8-h night shifts, with the arrangements differing by condition...
November 16, 2017: Chronobiology International
https://www.readbyqxmd.com/read/29137850/the-importance-of-subclinical-left-ventricular-dysfunction-and-blood-pressure-pattern-in-asymptomatic-type-2-diabetic-patients-the-diagnostic-and-prognostic-significance-of-tissue-doppler-parameters-left-ventricular-global-longitudinal-strain-and-nighttime
#9
Angelina Stevanovic, Milica Dekleva
The primary aims of this study have been to explore the diagnostic and prognostic significance of Tissue Doppler parameters (TDI), global longitudinal strain (GLS), and blood pressure (BP) pattern in normotensive diabetic patients. METHODS: The study consisted of 121 diabetic patients and 41 healthy subjects. Conventional and TDI echocardiography were performed on all patients, including E/Em (ratio of diastolic velocities). GLS was derived from two-dimensional speckle-tracking. Ambulatory BP monitoring (ABPM) was obtained over 24h...
September 18, 2017: Journal of Diabetes and its Complications
https://www.readbyqxmd.com/read/29126462/prediction-of-drowsiness-events-in-night-shift-workers-during-morning-driving
#10
Yulan Liang, William J Horrey, Mark E Howard, Michael L Lee, Clare Anderson, Michael S Shreeve, Conor S O'Brien, Charles A Czeisler
The morning commute home is an especially vulnerable time for workers engaged in night shift work due to the heightened risk of experiencing drowsy driving. One strategy to manage this risk is to monitor the driver's state in real time using an in vehicle monitoring system and to alert drivers when they are becoming sleepy. The primary objective of this study is to build and evaluate predictive models for drowsiness events occurring in morning drives using a variety of physiological and performance data gathered under a real driving scenario...
November 7, 2017: Accident; Analysis and Prevention
https://www.readbyqxmd.com/read/29114029/rapid-selection-free-high-efficiency-genome-editing-in-protozoan-parasites-using-crispr-cas9-ribonucleoproteins
#11
Lia Carolina Soares Medeiros, Lilith South, Duo Peng, Juan M Bustamante, Wei Wang, Molly Bunkofske, Natasha Perumal, Fernando Sanchez-Valdez, Rick L Tarleton
Trypanosomatids (order Kinetoplastida), including the human pathogens Trypanosoma cruzi (agent of Chagas disease), Trypanosoma brucei, (African sleeping sickness), and Leishmania (leishmaniasis), affect millions of people and animals globally. T. cruzi is considered one of the least studied and most poorly understood tropical disease-causing parasites, in part because of the relative lack of facile genetic engineering tools. This situation has improved recently through the application of clustered regularly interspaced short palindromic repeats-CRISPR-associated protein 9 (CRISPR-Cas9) technology, but a number of limitations remain, including the toxicity of continuous Cas9 expression and the long drug marker selection times...
November 7, 2017: MBio
https://www.readbyqxmd.com/read/29111422/shorter-sleep-duration-and-longer-sleep-onset-latency-are-related-to-difficulty-disengaging-attention-from-negative-emotional-images-in-individuals-with-elevated-transdiagnostic-repetitive-negative-thinking
#12
Jacob A Nota, Meredith E Coles
BACKGROUND AND OBJECTIVES: Repetitive negative thinking (RNT) is often associated with disruptions in sleep and circadian rhythms. Disruptions in sleep and circadian rhythms may deal a "second hit" to attentional control deficits. This study evaluated whether sleep and circadian rhythm disruptions are related to the top-down control of attention to negative stimuli in individuals with heightened repetitive negative thinking. METHODS: Fifty-two community adults with high levels of transdiagnostic RNT and varying habitual sleep durations and bedtimes participated in a hybrid free-viewing and directed attention task using pairs of emotionally-evocative and neutral images while eye-tracking data were collected...
October 19, 2017: Journal of Behavior Therapy and Experimental Psychiatry
https://www.readbyqxmd.com/read/29072062/morpho-functional-cardiovascular-adaptation-in-hypertensive-patients-two-dimensional-speckle-tracking-echocardiographic-study
#13
Ines P Monte, Chiara DI Benedetto, Filippo A Atanasio, Valentina Losi, Salvatore Licciardi, Corrado Tamburino
BACKGROUND: Twenty-four-hour Blood Pressure (BP) variability is an important predictor of organ damage and cardiovascular events. Although epidemiological data are widely based on evaluation of office (Clinic) BP, 24-hour Ambulatory BP monitoring (ABPM) accurately assess the severity of hypertension to predict cardiovascular events in hypertensive patients, because it more accurately reflects BP load on heart and blood vessels. Conventional transthoracic echocardiography (TTE), such as M-mode and two-dimensional (2D), and more advanced techniques, such as tissue Doppler imaging (TDI) and speckle tracking echocardiography (STE), are used to identify pathological changes of the hypertensive heart disease...
October 25, 2017: Minerva Cardioangiologica
https://www.readbyqxmd.com/read/29062537/tea-talk-and-technology-patient-and-public-involvement-to-improve-connected-health-wearables-research-in-dementia
#14
Lamiece Hassan, Caroline Swarbrick, Caroline Sanders, Angela Parker, Matt Machin, Mary P Tully, John Ainsworth
PLAIN ENGLISH SUMMARY: There are a growing number of mobile phones, watches and electronic devices which can be worn on the body to track aspects of health and well-being, such as daily steps, sleep and exercise. Dementia researchers think that these devices could potentially be used as part of future research projects, for example to help spot changes in daily activity that may signal the early symptoms of dementia. We asked a range of older people, including people living with dementia and their carers, to participate in interactive discussions about how future participants might find using these devices as part of research projects...
2017: Research Involvement and Engagement
https://www.readbyqxmd.com/read/29060734/comparison-of-motion-based-analysis-to-thermal-based-analysis-of-thermal-video-in-the-extraction-of-respiration-patterns
#15
Stephanie L Bennett, Rafik Goubran, Frank Knoefel
Non-contact methods of extracting vital signals has become a popular area of research. This is likely due to the world's aging population and the increased need for long term and remote monitoring. This paper examines and compares the potential for one modality to capture a vital sign, specifically respiration, in the presence of signal abnormalities. This paper compares temperature based-methods to motion-based methods of extracting respiration rate from thermal video of a subject performing computationally difficult respiration tests...
July 2017: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/29060055/a-novel-hfo-based-method-for-unsupervised-localization-of-the-seizure-onset-zone-in-drug-resistant-epilepsy
#16
Paige M Murphy, Adam J von Paternos, Sabato Santaniello
High frequency oscillations (HFOs) are potential biomarkers of epileptic areas. In patients with drug-resistant epilepsy, HFO rates tend to be higher in the seizure onset zone (SOZ) than in other brain regions and the resection of HFO-generating areas positively correlates with seizure-free surgery outcome. Nonetheless, the development of robust unsupervised HFO-based tools for SOZ localization remains challenging. Current approaches predict the SOZ by processing small samples of intracranial EEG (iEEG) data and applying patient-specific thresholds on the HFO rate...
July 2017: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/29054877/ontogeny-of-circadian-rhythms-and-synchrony-in-the-suprachiasmatic-nucleus
#17
Vania Carmona-Alcocer, John H Abel, Tao C Sun, Linda R Petzold, Francis J Doyle, Carrie L Simms, Erik D Herzog
In mammals, the suprachiasmatic nucleus (SCN) of the hypothalamus coordinates daily rhythms including sleep-wake, hormone release and gene expression. The cells of the SCN must synchronize to each other to drive these circadian rhythms in the rest of the body. The ontogeny of circadian cycling and intercellular coupling in the SCN remains poorly understood. Recent in vitro studies have recorded circadian rhythms from the whole embryonic SCN. Here, we tracked the onset and precision of rhythms in PERIOD2 (PER2), a clock protein, within the SCN isolated from embryonic and postnatal mice of undetermined sex...
October 20, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/29046786/sedentary-time-among-primary-school-children-in-south-west-germany-amounts-and-correlates
#18
Belinda Hoffmann, Sarah Kettner, Tamara Wirt, Olivia Wartha, Lina Hermeling, Jürgen M Steinacker, Susanne Kobel
BACKGROUND: Sedentary behaviour in children is related to different health consequences such as overweight and cardio-metabolic diseases that can track into adulthood. Previous studies have shown that children spend hours being sedentary, but no data of sedentary time (ST) among German children has been available, yet. Therefore, this study investigated objectively measured amounts and correlates of ST in a sample of German primary school children. METHODS: Children's physical activity (PA) was objectively assessed for 6 days using a multi-sensor device (Actiheart®; CamNtech, Cambridge, UK)...
2017: Archives of Public Health, Archives Belges de Santé Publique
https://www.readbyqxmd.com/read/29038553/a-comparison-of-passive-and-active-estimates-of-sleep-in-a-cohort-with-schizophrenia
#19
Patrick Staples, John Torous, Ian Barnett, Kenzie Carlson, Luis Sandoval, Matcheri Keshavan, Jukka-Pekka Onnela
Sleep abnormalities are considered an important feature of schizophrenia, yet convenient and reliable sleep monitoring remains a challenge. Smartphones offer a novel solution to capture both self-reported and objective measures of sleep in schizophrenia. In this three-month observational study, 17 subjects with a diagnosis of schizophrenia currently in treatment downloaded Beiwe, a platform for digital phenotyping, on their personal Apple or Android smartphones. Subjects were given tri-weekly ecological momentary assessments (EMAs) on their own smartphones, and passive data including accelerometer, GPS, screen use, and anonymized call and text message logs was continuously collected...
October 16, 2017: NPJ Schizophrenia
https://www.readbyqxmd.com/read/29035666/examination-of-risk-for-sleep-disordered-breathing-among-college-football-players
#20
Bailey Peck, Timothy Renzi, Hannah Peach, Jane Gaultney, Joseph S Marino
CONTEXT: Professional football linemen are at risk for sleep disordered breathing (SDB) compared to other types of athletes. It is currently unknown whether collegiate football linemen display a similar risk profile. OBJECTIVE: 1) Determine for the first time whether collegiate football linemen show risk for SDB, and 2) Test the hypothesis that SDB risk is higher in collegiate football linemen compared to an athletic comparison group. DESIGN: Descriptive laboratory study...
October 16, 2017: Journal of Sport Rehabilitation
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