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https://www.readbyqxmd.com/read/28436583/physical-activity-and-exercise-for-chronic-pain-in-adults-an-overview-of-cochrane-reviews
#1
REVIEW
Louise J Geneen, R Andrew Moore, Clare Clarke, Denis Martin, Lesley A Colvin, Blair H Smith
BACKGROUND: Chronic pain is defined as pain lasting beyond normal tissue healing time, generally taken to be 12 weeks. It contributes to disability, anxiety, depression, sleep disturbances, poor quality of life, and healthcare costs. Chronic pain has a weighted mean prevalence in adults of 20%.For many years, the treatment choice for chronic pain included recommendations for rest and inactivity. However, exercise may have specific benefits in reducing the severity of chronic pain, as well as more general benefits associated with improved overall physical and mental health, and physical functioning...
April 24, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28419646/suvorexant-an-orexin-hypocretin-receptor-antagonist-attenuates-motivational-and-hedonic-properties-of-cocaine
#2
Taylor A Gentile, Steven J Simmons, David J Barker, Jessica K Shaw, Rodrigo A España, John W Muschamp
Orexins ('hypocretins') are peptides produced by neurons of the hypothalamus that project to structures implicated in reward and emotion processing. Converging evidence demonstrates functional roles of orexin signaling in arousal, sleep/wakefulness and motivated behaviors for natural and drug rewards. Suvorexant, a dual orexin receptor antagonist, recently received approval from the US Food and Drug Administration to treat insomnia. In Experiment 1, rats self-administered cocaine under a progressive-ratio schedule of reinforcement and the effects of suvorexant on motivation to self-administer cocaine were measured...
April 17, 2017: Addiction Biology
https://www.readbyqxmd.com/read/28419607/subjective-and-objective-sleep-quality-modulate-emotion-regulatory-brain-function-in-anxiety-and-depression
#3
Heide Klumpp, Julia Roberts, Mary C Kapella, Amy E Kennedy, Anand Kumar, K Luan Phan
BACKGROUND: Disturbances in emotion regulation and sleep are shared across anxiety and mood disorders. Poor sleep has been shown to impair cognitive processes which may undermine cognitive regulatory function. However, it remains unknown if sleep quality impacts regulatory mechanisms in clinical anxiety and depression. METHODS: During fMRI, 78 patients with social anxiety disorder, generalized anxiety disorder, and/or major depressive disorder completed a validated emotion regulation task, which involved reappraisal (i...
April 18, 2017: Depression and Anxiety
https://www.readbyqxmd.com/read/28411116/global-field-synchronization-in-gamma-range-of-the-sleep-eeg-tracks-sleep-depth-artifact-introduced-by-a-rectangular-analysis-window
#4
Thomas Rusterholz, Peter Achermann, Roland Dürr, Thomas Koenig, Leila Tarokh
BACKGROUND: Investigating functional connectivity between brain networks has become an area of interest in neuroscience. Several methods for investigating connectivity have recently been developed, however, these techniques need to be applied with care. We demonstrate that global field synchronization (GFS), a global measure of phase alignment in the EEG as a function of frequency, must be applied considering signal processing principles in order to yield valid results. NEW METHOD: Multichannel EEG (27 derivations) was analyzed for GFS based on the complex spectrum derived by the fast Fourier transform (FFT)...
April 11, 2017: Journal of Neuroscience Methods
https://www.readbyqxmd.com/read/28406474/daily-touchscreen-use-in-infants-and-toddlers-is-associated-with-reduced-sleep-and-delayed-sleep-onset
#5
Celeste H M Cheung, Rachael Bedford, Irati R Saez De Urabain, Annette Karmiloff-Smith, Tim J Smith
Traditional screen time (e.g. TV and videogaming) has been linked to sleep problems and poorer developmental outcomes in children. With the advent of portable touchscreen devices, this association may be extending down in age to disrupt the sleep of infants and toddlers, an age when sleep is essential for cognitive development. However, this association has not been demonstrated empirically. This study aims to examine whether frequency of touchscreen use is associated with sleep in infants and toddlers between 6 and 36 months of age...
April 13, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28325004/study-of-phase-estimation-methods-to-analyse-cardiorespiratory-synchronization-in-osa-patients
#6
Jordi Sola-Soler, Beatriz F Giraldo, Jose A Fiz, Raimon Jane
Obstructive Sleep Apnea (OSA) is a sleep disorder highly prevalent in the general population. Cardiorespiratory Phase Synchronization (CRPS) is a form of non-linear interaction between respiratory and cardiovascular systems that was found to be reduced in severe OSA patients. The Hilbert Transform (HT) method was the recommended choice for estimating the respiratory phase in CRPS studies. But we have noticed that HT provides a phase that is aligned to the transition between the exhalation and the inhalation parts of different breathing cycles, instead of being aligned to the breathing onsets...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28295424/long-term-future-risk-of-severe-exacerbations-distinct-5-year-trajectories-of-problematic-asthma
#7
Anthony C A Yii, Jessica H Y Tan, Therese S Lapperre, Adrian K W Chan, Su Y Low, Thun H Ong, Keng L Tan, Sanjay H Chotirmall, Peter J Sterk, Mariko S Koh
BACKGROUND: Assessing future risk of exacerbations is an important component of asthma management. Existing studies have investigated short-, but not long-term risk. Problematic asthma patients with unfavorable long-term disease trajectory and persistently frequent severe exacerbations need to be identified early to guide treatment. METHODS: Severe exacerbation rates over five years for 177 "problematic asthma" patients presenting to a specialist asthma clinic were tracked...
March 11, 2017: Allergy
https://www.readbyqxmd.com/read/28293622/sleeping-with-an-android
#8
Beenish M Chaudhry
Sleep quality and duration are strong indicators of an individual's health and quality of lifebut they are difficult to track in everyday life. Mobile apps such as Sleep as Android leverage smartphone sensors to track sleep patterns and make recommendations to improve sleeping habits.
2017: MHealth
https://www.readbyqxmd.com/read/28282238/changes-in-the-sleep-wake-rhythm-sleep-quality-mood-and-quality-of-life-of-patients-receiving-treatment-for-lung-cancer-a-longitudinal-study
#9
Wen-Pei Chang, Chia-Chin Lin
Studies on the diurnal sleep-wake rhythm of patients with lung cancer have mostly examined patients cross-sectionally, whereas the effects of lung cancer treatment over time have rarely been considered. Through long-term longitudinal tracking of patients with lung cancer, this study examined changes in their sleep-wake rhythm, sleep quality, anxiety, depressive symptoms, fatigue and quality of life (QoL) at various treatment stages. In addition, factors affecting their QoL were explored. Hierarchical linear modeling was adopted to analyze a convenience sample of 82 patients with lung cancer...
2017: Chronobiology International
https://www.readbyqxmd.com/read/28281106/tracking-daily-fatigue-fluctuations-in-multiple-sclerosis-ecological-momentary-assessment-provides-unique-insights
#10
Daniel J H Powell, Christina Liossi, Wolff Schlotz, Rona Moss-Morris
Studies investigating the prevalence, cause, and consequence of multiple sclerosis (MS) fatigue typically use single measures that implicitly assume symptom-stability over time, neglecting information about if, when, and why severity fluctuates. We aimed to examine the extent of moment-to-moment and day-to-day variability in fatigue in relapsing-remitting MS and healthy individuals, and identify daily life determinants of fluctuations. Over 4 weekdays, 76 participants (38 relapsing-remitting MS; 38 controls) recruited from multiple sites provided real-time self-reports six times daily (n = 1661 observations analyzed) measuring fatigue severity, stressors, mood, and physical exertion, and daily self-reports of sleep quality...
March 9, 2017: Journal of Behavioral Medicine
https://www.readbyqxmd.com/read/28279451/data-driven-models-to-predict-the-elimination-of-sleeping-sickness-in-former-equateur-province-of-drc
#11
K S Rock, A Pandey, M L Ndeffo-Mbah, K E Atkins, C Lumbala, A Galvani, M J Keeling
Approaching disease elimination, it is crucial to be able to assess progress towards key objectives using quantitative tools. For Gambian human African trypanosomiasis (HAT), the ultimate goal is to stop transmission by 2030, while intermediary targets include elimination as a public health problem - defined as <1 new case per 10,000 inhabitants in 90% of foci, and <2000 reported cases by 2020. Using two independent mathematical models, this study assessed the achievability of these goals in the former Equateur province of the Democratic Republic of Congo, which historically had endemic levels of disease...
March 2017: Epidemics
https://www.readbyqxmd.com/read/28269372/smart-monitoring-of-fluid-intake-and-bladder-voiding-using-pressure-sensitive-mats
#12
Madison Cohen-McFarlane, James R Green, Frank Knoefel, Rafik Goubran
Pressure sensitive mats have been used in noninvasive smart monitoring for a variety of problems including breathing rate monitoring, sleep monitoring, mobility, and weight. This paper describes a proof of concept application of pressure mats to monitor fluid intake/output (fluid cycle) events during the night. The ability to more accurately track such events has potential implications for monitoring those individuals who have nocturia, a condition where a person wakes at night to urinate. Data were collected from a healthy young female subject instructed to drink as much water as was comfortable (700mL) and lie in a supine position on a mattress located directly on three pressure mats...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28269370/bed-based-instrumentation-for-unobtrusive-sleep-quality-assessment-in-severely-disabled-autistic-children
#13
Charles Carlson, Ahmad Suliman, Punit Prakash, David Thompson, Shangxian Wang, Bala Natarajan, Steve Warren
The relationship between sleep quality and daytime wellness and performance in severely disabled, autistic children is not well understood. While polysomnography and, more recently, actigraphy serve as means to obtain sleep assessment data from neurotypical children and adults, these techniques are not well-suited to severely autistic children. This paper presents recent progress on a bed sensor suite that can unobtrusively track physiological and behavioral parameters used to assess sleep quality. Electromechanical films and load cells provide data that yield heart rate, respiration rate, center of position, in-and-out-of-bed activity, and general movement, while thermocouples are used to detect bed-wetting events...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28268691/design-and-preliminary-evaluation-of-a-wearable-device-for-mass-screening-of-sleep-apnea
#14
Rohan S Puri, Athanasios G Athanassiadis, Niharika Gill, Sai Sri Sathya, Geetanjali Rathod, Akshat Wahi, Guy Satat, Maulik Majmudar, Pratik Shah
Between 7-18 million Americans suffer from sleep disordered breathing (SDB), including those who suffer from obstructive sleep apnea (OSA). Despite this high prevalence and burden of OSA, existing diagnostic techniques remain impractical for widespread screening. In this study, we introduce a new model for OSA screening and describe an at-home wearable sleep mask (named ARAM) that can robustly track the wearers' sleep patterns. This monitoring is achieved using select sensors that enable screening and monitoring in a form-factor that can be easily self-instrumented...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28263253/executive-function-is-associated-with-off-line-motor-learning-in-people-with-chronic-stroke
#15
Mayis Al-Dughmi, Alham Al-Sharman, Suzanne Stevens, Catherine F Siengsukon
BACKGROUND AND PURPOSE: Sleep has been shown to promote off-line motor learning in individuals following stroke. Executive function ability has been shown to be a predictor of participation in rehabilitation and motor recovery following stroke. The purpose of this study was to explore the association between executive function and off-line motor learning in individuals with chronic stroke compared with healthy control participants. METHODS: Seventeen individuals with chronic stroke (>6 months poststroke) and 9 healthy adults were included in the study...
April 2017: Journal of Neurologic Physical Therapy: JNPT
https://www.readbyqxmd.com/read/28262785/a-novel-ideal-radionuclide-imaging-system-for-non-invasively-cell-monitoring-built-on-baculovirus-backbone-by-introducing-sleeping-beauty-transposon
#16
Jing Lv, Yu Pan, Huijun Ju, Jinxin Zhou, Dengfeng Cheng, Hongcheng Shi, Yifan Zhang
Sleeping Beauty (SB) transposon is an attractive tool in stable transgene integration both in vitro and in vivo; and we introduced SB transposon into recombinant sodium-iodide symporter baculovirus system (Bac-NIS system) to facilitate long-term expression of recombinant sodium-iodide symporter. In our study, two hybrid baculovirus systems (Bac-eGFP-SB-NeoR and Bac-NIS-SB-NeoR) were successfully constructed and used to infect U87 glioma cells. After G418 selection screening, the Bac-eGFP-SB-NeoR-U87 cells remained eGFP positive, at the 18(th) and 196(th) day post transfection (96...
March 6, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28259336/shift-schedules-and-intern-work-hours-patient-numbers-conference-attendance-and-sleep-at-a-single-pediatric-residency-program
#17
Irene Kocolas, Kristen Day, Marta King, Adam Stevenson, Xiaoming Sheng, Wendy Hobson, Jaime Bruse, James Bale
OBJECTIVE: The effects of 2011 Accreditation Council on Graduate Medical Education (ACGME) duty hour standards on intern work hours, patient load, conference attendance, and sleep have not been fully determined. We prospectively compared intern work hours, patient numbers, conference attendance, sleep duration, pattern, and quality in a 2011 ACGME duty hour-compliant shift schedule with a 2003 ACGME duty hour-compliant call schedule at a single pediatric residency program. METHODS: Interns were assigned to shift or call schedules during 4 alternate months in the winter of 2010-2011...
March 2017: Academic Pediatrics
https://www.readbyqxmd.com/read/28241473/a-mobility-aware-adaptive-duty-cycling-mechanism-for-tracking-objects-during-tunnel-excavation
#18
Taesik Kim, Hong Min, Jinman Jung
Tunnel construction workers face many dangers while working under dark conditions, with difficult access and egress, and many potential hazards. To enhance safety at tunnel construction sites, low latency tracking of mobile objects (e.g., heavy-duty equipment) and construction workers is critical for managing the dangerous construction environment. Wireless Sensor Networks (WSNs) are the basis for a widely used technology for monitoring the environment because of their energy-efficiency and scalability. However, their use involves an inherent point-to-point delay caused by duty cycling mechanisms that can result in a significant rise in the delivery latency for tracking mobile objects...
February 23, 2017: Sensors
https://www.readbyqxmd.com/read/28227615/smart-monitoring-of-fluid-intake-and-bladder-voiding-using-pressure-sensitive-mats
#19
Madison Cohen-McFarlane, James R Green, Frank Knoefel, Rafik Goubran, Madison Cohen-McFarlane, James R Green, Frank Knoefel, Rafik Goubran, Frank Knoefel, Madison Cohen-McFarlane, Rafik Goubran, James R Green
Pressure sensitive mats have been used in noninvasive smart monitoring for a variety of problems including breathing rate monitoring, sleep monitoring, mobility, and weight. This paper describes a proof of concept application of pressure mats to monitor fluid intake/output (fluid cycle) events during the night. The ability to more accurately track such events has potential implications for monitoring those individuals who have nocturia, a condition where a person wakes at night to urinate. Data were collected from a healthy young female subject instructed to drink as much water as was comfortable (700mL) and lie in a supine position on a mattress located directly on three pressure mats...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227612/bed-based-instrumentation-for-unobtrusive-sleep-quality-assessment-in-severely-disabled-autistic-children
#20
Charles Carlson, Ahmad Suliman, Punit Prakash, David Thompson, Shangxian Wang, Bala Natarajan, Steve Warren, Charles Carlson, Ahmad Suliman, Punit Prakash, David Thompson, Shangxian Wang, Bala Natarajan, Steve Warren, Shangxian Wang, Punit Prakash, Bala Natarajan, David Thompson, Charles Carlson, Steve Warren, Ahmad Suliman
The relationship between sleep quality and daytime wellness and performance in severely disabled, autistic children is not well understood. While polysomnography and, more recently, actigraphy serve as means to obtain sleep assessment data from neurotypical children and adults, these techniques are not well-suited to severely autistic children. This paper presents recent progress on a bed sensor suite that can unobtrusively track physiological and behavioral parameters used to assess sleep quality. Electromechanical films and load cells provide data that yield heart rate, respiration rate, center of position, in-and-out-of-bed activity, and general movement, while thermocouples are used to detect bed-wetting events...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
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