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https://www.readbyqxmd.com/read/28346782/%C3%AE%C2%BA-carrageenan-enhances-the-biomineralization-and-osteogenic-differentiation-of-electrospun-phb-and-phbv-fibers
#1
Nowsheen Goonoo, Behnam Khanbabaee, Marc Steuber, Archana Bhaw-Luximon, Ulrich Jonas, Ullrich Pietsch, Dhanjay Jhurry, Holger Schönherr
Novel electrospun materials for bone tissue engineering were obtained by blending biodegradable polyhydroxybutyrate (PHB) or polyhydroxybutyrate valerate (PHBV) with the anionic sulfated polysaccharide κ-carrageenan (κ-CG) in varying ratios. In both systems, the two components phase separated as shown by FTIR, DSC and TGA. According to the contact angle data, κ-CG was localized preferentially at the fiber surface in PHBV/ κ-CG blends in contrast to PHB/ κ-CG, where the biopolymer was mostly found within the fiber...
March 27, 2017: Biomacromolecules
https://www.readbyqxmd.com/read/28346219/semiconductor-devices-for-entangled-photon-pair-generation-a-review
#2
Adeline Orieux, Marijn A M Versteegh, Klaus Jöns, Sara Ducci
Entanglement is one of the most fascinating properties of quantum mechanical systems; when two particles are entangled the measurement of the properties of one of the two allows to instantaneously know the properties of the other, whatever the distance separating them. In parallel with fundamental research on the foundations of quantum mechanics performed on complex experimental set-ups, we assist today to a bourgeoning of quantum information technologies bound to exploit entanglement for a large variety of applications such as secure communications, metrology and computation...
March 27, 2017: Reports on Progress in Physics
https://www.readbyqxmd.com/read/28345859/aqueous-nanoparticle-polymer-solar-cells-the-effects-of-surfactant-concentration-and-processing-on-device-performance
#3
Fallon J M Colberts, Martijn M Wienk, René A J Janssen
Polymer solar cells based on PDPP5T and PCBM as donor and acceptor materials have been processed from aqueous nanoparticle miniemulsions. Careful monitoring and optimizing the concentration of free and surface-bound surfactants in the dispersion, by measuring the conductivity and zeta potential, is essential to avoid aggregation of nanoparticles at low concentration and de-wetting of the film at high concentration. The surfactant concentration is crucial for creating reproducible processing conditions that aid in further developing aqueous nanoparticle processed solar cells...
March 27, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28345817/simultaneous-determination-of-multiple-active-components-in-rat-plasma-using-ultra-fast-liquid-chromatography-with-tandem-mass-spectrometry-and-application-to-a-comparative-pharmacokinetic-study-after-oral-administration-of-suan-zao-ren-decoction-and-suan-zao
#4
Yiyang Du, Bosai He, Qing Li, Jiao He, Di Wang, Kaishun Bi
Suan-Zao-Ren decoction has been used to treat insomnia for many years. In this work, a rapid and sensitive ultra-fast liquid chromatography with tandem mass spectrometry method was first developed and fully validated for the simultaneous quantification of seven main active components, spinosin, mangiferin, neomangiferin, ferulic acid, liquiritin, isoliquiritin and liquiritin apioside in rat plasma. The method was also successfully applied to compare the pharmacokinetics of these active ingredients after oral administration of Suan-Zao-Ren decoction and Suan-Zao-Ren granule...
March 27, 2017: Journal of Separation Science
https://www.readbyqxmd.com/read/28345247/functional-morphological-adaptations-of-the-bony-labyrinth-in-marsupials-mammalia-theria
#5
Cathrin Pfaff, Stefan Czerny, Doris Nagel, Jürgen Kriwet
Diprotodontia represents the largest and ecologically most distinct order of marsupials occurring in Australasian being highly divers in size, locomotion, habitat preferences, feeding, and activity pattern. The spatial orientation in the habitat and therefore the three-dimensional space is detected by the vestibular system of the inner ear, more precisely by the three semicircular canals. In this study, we investigated the bony labyrinth of diprotodontian and selected non-diprotodontian marsupial mammals of almost all genera with noninvasive micro-CT scanning and 3D-reconstructions...
March 27, 2017: Journal of Morphology
https://www.readbyqxmd.com/read/28344947/factors-associated-with-odontogenic-bacteraemia-in-orthodontic-patients
#6
O D Umeh, O O Sanu, I L Utomi, F O Nwaokorie
BACKGROUND: Various researches have investigated factors associated with the prevalence and intensity of bacteraemia following oral procedures including orthodontic procedures. AIM: The aim of this study was to determine the effect of age, gender, plaque and gingival indices on the occurrence of odontogenic bacteraemia following orthodontic treatment procedures. SETTING: Orthodontic Clinic, Lagos University Teaching Hospital (LUTH), Lagos, Nigeria...
April 2016: Journal of the West African College of Surgeons
https://www.readbyqxmd.com/read/28344493/volatile-constituents-and-biological-activities-of-the-leaf-and-root-of-echinacea-species-from-south-africa
#7
M Nyalambisa, I A Oyemitan, R Matewu, O O Oyedeji, O S Oluwafemi, S P Songca, B N Nkeh-Chungag, A O Oyedeji
Echinacea is used ethnomedicinally for the treatment of various diseases such as cough, respiratory infections, and bronchitis among other uses in Eastern Cape region of South Africa. This study evaluated the volatile components of the essential oil of the plant, its toxicity, anti-inflammatory and analgesic activities in rodents. Dried leaf and root of the plant were separately processed by hydrodistillation for 4 h and their essential oils (EOs) were collected. Extracted oils were subjected to GC/GC-MS analysis...
March 2017: Saudi Pharmaceutical Journal: SPJ: the Official Publication of the Saudi Pharmaceutical Society
https://www.readbyqxmd.com/read/28344446/prediction-of-tennis-performance-in-junior-elite-tennis-players
#8
Tamara Kramer, Barbara C H Huijgen, Marije T Elferink-Gemser, Chris Visscher
Predicting current and future tennis performance can lead to improving the development of junior tennis players. The aim of this study is to investigate whether age, maturation, or physical fitness in junior elite tennis players in U13 can explain current and future tennis performance. The value of current tennis performance for future tennis performance is also investigated. A total of 86 junior elite tennis players (boys, n = 44; girls, n = 42) U13 (aged: 12.5 ± 0.3 years), and followed to U16, took part in this study...
March 2017: Journal of Sports Science & Medicine
https://www.readbyqxmd.com/read/28344364/improved-electroanalytical-characteristics-for-flumetralin-determination-in-the-presence-of-surface-active-compound
#9
Dariusz Guziejewski, Sylwia Smarzewska, Radovan Metelka, Agnieszka Nosal-Wiercińska, Witold Ciesielski
ABSTRACT: The use of square wave voltammetry (SWV) and square wave adsorptive stripping voltammetry (SWAdSV) in conjunction with a cyclic renewable silver amalgam film electrode for the determination of flumetralin is presented. Poor separation of two overlapped reduction peaks is significantly improved when hexadecyltrimethylammonium bromide is used as a component of the supporting electrolyte solution (together with BR buffer pH 9.5). The SW technique parameters were investigated and found optimal as follows: frequency 50 Hz, amplitude 40 mV, and step potential 5 mV...
2017: Monatshefte Für Chemie
https://www.readbyqxmd.com/read/28344332/molecular-and-functional-heterogeneity-of-early-postnatal-porcine-satellite-cell-populations-is-associated-with-bioenergetic-profile
#10
Claudia Miersch, Katja Stange, Silvio Hering, Martin Kolisek, Torsten Viergutz, Monika Röntgen
During postnatal development, hyperplastic and hypertrophic processes of skeletal muscle growth depend on the activation, proliferation, differentiation, and fusion of satellite cells (SC). Therefore, molecular and functional SC heterogeneity is an important component of muscle plasticity and will greatly affect long-term growth performance and muscle health. However, its regulation by cell intrinsic and extrinsic factors is far from clear. In particular, there is only minor information on the early postnatal period which is critical for muscle maturation and the establishment of adult SC pools...
March 27, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28344131/specific-patterns-of-spinal-metabolites-underlying-%C3%AE-me-5-ht-evoked-pruritus-compared-with-histamine-and-capsaicin-assessed-by-proton-nuclear-magnetic-resonance-spectroscopy
#11
Taotao Liu, Zhigang He, Xuebi Tian, Ghulam Mustafa Kamal, Zhixiao Li, Zeyuan Liu, Huili Liu, Fuqiang Xu, Jie Wang, Hongbing Xiang
The mechanism behind itching is not well understood. Proton nuclear magnetic resonance ((1)H-NMR) spectroscopic analysis of spinal cord extracts provides a quick modality for evaluating the specific metabolic activity of α-Me-5-HT-evoked pruritus mice. In the current study, four groups of young adult male C57Bl/6 mice were investigated; one group treated with saline, while the other groups intradermally injected with α-Me-5-HT (histamine independent pruritogen), histamine (histamine dependent pruritogen) and capsaicin (algogenic substance), respectively...
March 23, 2017: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/28343079/population-model-of-bladder-motion-and-deformation-based-on-dominant-eigenmodes-and-mixed-effects-models-in-prostate-cancer-radiotherapy
#12
Richard Rios, Renaud De Crevoisier, Juan D Ospina, Frederic Commandeur, Caroline Lafond, Antoine Simon, Pascal Haigron, Jairo Espinosa, Oscar Acosta
In radiotherapy for prostate cancer irradiation of neighboring organs at risk may lead to undesirable side-effects. Given this setting, the bladder presents the largest inter-fraction shape variations hampering the computation of the actual delivered dose vs. planned dose. This paper proposes a population model, based on longitudinal data, able to estimate the probability of bladder presence during treatment, using only the planning computed tomography (CT) scan as input information. As in previously-proposed principal component analysis (PCA) population-based models, we have used the data to obtain the dominant eigenmodes that describe bladder geometric variations between fractions...
March 8, 2017: Medical Image Analysis
https://www.readbyqxmd.com/read/28343078/development-and-validation-of-liquid-chromatography-tandem-mass-spectrometry-method-quantitative-determination-of-polymyxin-b1-polymyxin-b2-polymyxin-b3-and-isoleucine-polymyxin-b1-in-human-plasma-and-its-application-in-clinical-studies
#13
Kim H Hee, Yee K J Leaw, Jun L Ong, Lawrence S Lee
Polymyxin B (PB) is an antibiotic consisting of a cyclic heptapeptide and a tripeptide side chain used in treatment of infections caused by Gram-negative bacteria. Commercial formulations of PB contain multiple structurally related components with major constituents of PB1, PB2, PB3 and ile-PB1. To understand the pharmacokinetics of these major components, we have developed and validated a LC-MS/MS method to quantify PB1, PB2, PB3 and ile-PB1 in human plasma. PB was extracted from plasma by protein precipitation using trichloroacetic acid followed by chromatographic separation on Zorbax Bonus-RP column (100mm×2...
March 14, 2017: Journal of Pharmaceutical and Biomedical Analysis
https://www.readbyqxmd.com/read/28342899/contributions-of-intestinal-epithelial-barriers-to-health-and-disease
#14
REVIEW
Wangsun Choi, Sunil Yeruva, Jerrold R Turner
A core function of epithelia is to form barriers that separate tissue compartments within complex organisms. These barriers also separate the internal milieu from the external environment and are, therefore, an essential component of host defense. However, in many cases, a perfect barrier would be improbable with life itself. Examples include the air spaces within the lungs, the renal tubules, and the intestines. Here, we focus on the mechanisms by which barriers are assembled, maintained, and regulated in the context of health and disease...
March 23, 2017: Experimental Cell Research
https://www.readbyqxmd.com/read/28342696/measurement-of-change-on-medial-and-lateral-joint-gaps-by-navigation-system-in-multi-radius-ps-tka
#15
Yeesuk Kim, Jin Kyu Lee, Kyu-Sung Chung, Doo-Yeon Lee, Choong Hyeok Choi
BACKGROUND: The purpose of this study was to evaluate the joint gap kinematics in posterior-stabilized total knee arthroplasty (PS TKA). METHODS: Between January 2010 and April 2011, 44 consecutive patients (55 knees) who underwent primary PS TKA using the navigation system were assessed. There were 37 women and 7 men with a mean age at operation of 63 years (range; 58-73 years). After fixation of all components with cement and insertion of polyethylene trial insert, medial and lateral joint gap measurements were carried out without distraction force and separately using a navigation system on each flexion angles...
March 22, 2017: Journal of Orthopaedic Science: Official Journal of the Japanese Orthopaedic Association
https://www.readbyqxmd.com/read/28342292/ultra-fast-liquid-chromatography-with-tandem-mass-spectrometry-determination-of-eight-bioactive-components-of-kai-xin-san-in-rat-plasma-and-its-application-to-a-comparative-pharmacokinetic-study-in-normal-and-alzheimer-s-disease-rats
#16
Xiaotong Wang, Yue Zhang, Huibin Niu, Yajing Geng, Bing Wang, Xiaomei Yang, Pengyu Yan, Qing Li, Kaishun Bi
A method of ultra-fast liquid chromatography with tandem mass spectrometry was developed and validated for the simultaneous quantitation of eight bioactive components, including polygalaxanthone III, sibiricaxanthone B, tenuifolin, sibiricose A5, sibiricose A6, tenuifoliside A, ginsenoside Re and ginsenoside Rb1 in rat plasma after oral administration of Kai-Xin-San. The plasma samples were extracted by liquid-liquid extraction using digoxin as internal standard. Chromatographic separation was performed on a Venusil MP C18 column (100 mm × 2...
March 25, 2017: Journal of Separation Science
https://www.readbyqxmd.com/read/28341309/polymorphic-distribution-of-proteins-in-solution-by-mass-spectrometry-the-analysis-of-insulin-analogues
#17
Maely P Fávero-Retto, Luiz Henrique Guerreiro, Cássio M Pessanha, Leonardo C Palmieri, Luís Maurício T R Lima
The characterization of conformational and oligomeric distribution of proteins is of paramount importance for the understanding of the correlation between structure and function. Among the bioanalytical approaches currently available, the electrospray ionization-mass spectrometry (ESI-MS) coupled to ion mobility spectrometry (IMS) is the best suited for high resolution identification with high sensitivity, allowing the in situ separation of oligomeric and conformational species. We tested the performance of the ESI-MS technique along with the IMS separation approach on a broad variety of insulin and insulin analogues with distinct oligomeric distribution pattern...
January 2017: Biologicals: Journal of the International Association of Biological Standardization
https://www.readbyqxmd.com/read/28340769/development-of-a-nano-sio2-based-enzyme-linked-ligand-binding-assay-for-the-determination-of-ibuprofen-in-human-urine
#18
Qian-Long Wang, Jing Xie, Xing-De Li, Li-Sheng Ding, Jian Liang, Pei Luo, Lin-Sen Qing
The application domains of classic enzyme-linked ligand binding assay (ELBA) is relatively narrow due to the high cost and hardly available binding receptor. In here, we described for the first time the possibility of developing a new ELBA based on silica nanoparticles (nano-SiO2) to assess the ibuprofen in human urine. Nano-SiO2 with a large surface area was introduced as stationary phase to improve the analytical performance. In the experiment, a competitively binding procedure with human serum albumin (HSA) was performed between the ibuprofen presented in sample and horseradish peroxidase labeled ibuprofen (HRP-ibuprofen) subsequently added...
May 15, 2017: Talanta
https://www.readbyqxmd.com/read/28340471/chemotaxonomic-studies-of-nine-paris-species-from-china-based-on-ultra-high-performance-liquid-chromatography-tandem-mass-spectrometry-and-fourier-transform-infrared-spectroscopy
#19
Yuanzhong Wang, Ehu Liu, Ping Li
Paris species, which contain steroid saponins, have been used as herb folk medicines in Asia. In the present study, a comprehensive strategy based on liquid chromatography-tandem mass spectrometry (LC-MS/MS) and Fourier transform infrared (FT-IR) spectroscopy was firstly proposed to evaluate the chemotaxonomic relationships of nine Paris species sampled from different geographical regions in China. Principle component analysis (PCA) based on FT-IR data revealed chemical similarities in term of the nine species and geographical regions, indicating the accumulation of metabolites affected by the combination of geographical factors and species...
March 18, 2017: Journal of Pharmaceutical and Biomedical Analysis
https://www.readbyqxmd.com/read/28338529/dosimetry-software-hermes-internal-radiation-dosimetry-from-quantitative-image-reconstruction-to-voxel-level-absorbed-dose-distribution
#20
Eero T Hippeläinen, Mikko J Tenhunen, Hanna O Mäenpää, Jorma J Heikkonen, Antti O Sohlberg
OBJECTIVE: The aim of this work is to validate a software package called Hermes Internal Radiation Dosimetry (HIRD) for internal dose assessment tailored for clinical practice. The software includes all the necessary steps to perform voxel-level absorbed dose calculations including quantitative reconstruction, image coregistration and volume of interest tools. METHODS: The basics of voxel-level dosimetry methods and implementations to HIRD software are reviewed...
March 23, 2017: Nuclear Medicine Communications
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