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Ghasem Fakhraie

Masoumeh Mohebi, Saeed Chenari, Abolfazl Akbari, Fariba Ghassemi, Mehran Zarei-Ghanavati, Ghasem Fakhraie, Nahid Babaie, Mansour Heidari
OBJECTIVES: Childhood cataract is a genetically heterogeneous eye disorder that results in visual impairment. The aim of this study was to identify the genetic mutations of connexin 50 gene among Iranian families suffered from autosomal dominant congenital cataracts (ADCC). MATERIALS AND METHODS: Families, having at least two members with bilateral familial congenital cataract, were selected for the study. Probands were evaluated by detailed ophthalmologist's examination, and the pedigree analysis was performed...
March 2017: Iranian Journal of Basic Medical Sciences
Ghasem Fakhraie, Zakieh Vahedian
PURPOSE: To report a case of unilateral post trabeculectomy globe massage-induced keratoconus (KCN). CASE REPORT: A 52-year-old lady with a history of trabeculectomy due to iridocorneal endothelial syndrome in her right eye was instructed to massage her globe to control gradual rise of intraocular pressure 1.5 years after surgery. The patient experienced high astigmatism and marked inferior corneal steepening after 3 years of globe massage. The left eye was normal in all aspects...
July 2016: Journal of Ophthalmic & Vision Research
Ghasem Fakhraie, Zahra Mohajernezhad-Fard, Sasan Moghimi, Zakieh Vahedian, Yadollah Eslami, Reza Zarei
PURPOSE: To evaluate the safety and efficacy of phacoemulsification for management of post-filtering ocular hypotony. METHODS: This prospective interventional case series study recruited 21 consecutive patients with an established diagnosis of ocular hypotony with or without maculopathy. Clear corneal incision phacoemulsification was done for all patients. Nineteen cases that completed a follow-up of at least 6 months were considered for final analysis. RESULTS: Mean baseline intraocular pressure (IOP) was 2...
October 2015: Journal of Ophthalmic & Vision Research
Sasan Moghimi, Mehdi Mazloumi, MohammadKarim Johari, Parisa Abdi, Ghasem Fakhraie, Massood Mohammadi, Reza Zarei, Yadollah Eslami, Masoud A Fard, Shan C Lin
PURPOSE: To evaluate the lamina cribrosa (LC) and peripapillary choroid in patients with pseudoexfoliation syndrome (PXS). METHODS: In this cross-sectional study, one eye each of 32 nonglaucomatous PXS cases and 29 healthy volunteers were enrolled. The optic discs were scanned using enhanced depth imaging spectral-domain optical coherence tomography, and measurements were obtained using HEYEX software 6.0. LC and other related variables at three areas (mid-superior, center, and mid-inferior) and peripapillary choroidal thickness were determined...
March 2016: Investigative Ophthalmology & Visual Science
Mohsen Yaghoubi, Maziar Moradi-Lakeh, Mehdi Mokhtari-Payam, Ghasem Fakhraie, Farhad Shokraneh
This systematic review was performed to estimate the diagnostic accuracy of the confocal scanning laser ophthalmoscopy in diagnosing glaucoma. We did a sensitive electronic search to find relevant studies. Two reviewers independently screened relevant articles and extracted required data about study methods and reported results of sensitivity and specificity. A meta-analysis was conducted for pooling data to compare different editions of the Heidelberg Retina Tomograph (HRT) with one of its alternatives, scanning laser polarimetry (GDx) with the criteria of "visual field defect" and "changes of nerve fiber layer" as the reference standard...
January 2015: Asia-Pacific Journal of Ophthalmology
Zakieh Vahedian, Heidar Amini, Mehdi Hosseini Tehrani, Reza Zarei, Sasan Moghimi, Maneli Mozaffarieh, Ghasem Fakhraie
BACKGROUND: The overall aim of this study was to determine retinal venous pressure (RVP) in healthy chronic smokers and compare values to those of healthy non-smokers. METHODS: Both eyes of 25 healthy chronic smokers and 41 healthy non-smokers were included. Measurements of RVP were performed by means of contact lens ophthalmodynamometry. Ophthalmodynamometry is done by applying increasing force on the eye via a contact lens. If a spontaneous venous pulsation was present, it was noted...
2015: EPMA Journal
Massood Mohammadi, Fatemeh Bazvand, Ali Makateb, Yadollah Eslami, Mahmood Jabbarvand Behrooz, Ghasem Fakhraie, Reza Zarei, Sasan Moghimi
PURPOSE: To compare anterior segment parameters in patients with central retinal vein occlusion (CRVO) with normal control subjects by anterior segment optical coherence tomography (AS-OCT). METHODS: In this coss-sectional case-control study, 42 eyes from 21 patients with unilateral CRVO and 21 eyes from 21 age- and sex-matched healthy control subjects were recruited. Study eyes were divided into three groups: involved eyes of CRVO patients (CRVO eyes), fellow eyes of CRVO patients (fellow eyes), and control eyes...
September 2015: Retina
Ghasem Fakhraie, Hadi Ghadimi, Yadollah Eslami, Reza Zarei, Massood Mohammadi, Zakieh Vahedian, Mostafa Mafi, Sasan Moghimi
PURPOSE: To investigate the outcome of trabeculectomy with or without adjunctive intracameral bevacizumab. MATERIALS AND METHODS: In this prospective, double-blind, randomized clinical trial, 71 patients with primary open-angle or pseudoexfoliation glaucoma were randomly assigned to receive either 1.25 mg intracameral bevacizumab (n=36) or balanced salt solution as placebo (n=35) at the end of trabeculectomy. Success was defined as at least a 30% drop in intraocular pressure (IOP) compared with baseline values and an IOP between 6 and 21 mm Hg at the last postoperative visit with (qualified) or without (complete) glaucoma medications...
March 2016: Journal of Glaucoma
Sasan Moghimi, Narges Zandvakil, Zakieh Vahedian, Massood Mohammadi, Ghasem Fakhraie, Anne L Coleman, Shan C Lin
BACKGROUND: To evaluate different mechanisms of acute angle closure and to compare it with unaffected fellow eyes and primary angle closure suspects using anterior segment optical coherence tomography. DESIGN: Prospective, cross-sectional. PARTICIPANTS: 116 eyes (76 patients) with angle closure disease were included. METHODS: Eyes were categorized into three groups: (i) acute angle closure (40 eyes); (ii) fellow eyes of acute angle closure (40 eyes); and (iii) primary angle closure suspect (36 eyes)...
September 2014: Clinical & Experimental Ophthalmology
Yadollah Eslami, Vafa Samarai, Massood Mohammadi, Ghasem Fakhraie, Reza Zarei, Sajad Eslami, Sasan Moghimi
To evaluate efficacy and safety of same site re-operation in eyes with failed trabeculectomy. A retrospective, noncomparative, interventional case series. We reviewed the medical records of 35 eyes of 35 patients who underwent same-site re-operation for failed trabeculectomy. The surgery involved a fornix-based peritomy at the same site as the previous trabeculectomy with application of 0.2 mg/mL mitomycin for 1 min. Primary outcome measures were intraocular pressure (IOP) control and number of antiglaucoma medications at last follow-up...
June 2014: International Ophthalmology
Sasan Moghimi, Golshan Latifi, Heydar Amini, Masood Mohammadi, Ghasem Fakhraie, Yadollah Eslami, Nariman Nassiri, Joseph Caprioli
PURPOSE: To evaluate the effect of cataract surgery on intraocular pressure (IOP) in filtered eyes with primary angle closure glaucoma (PACG). METHODS: In this prospective interventional case series, 37 previously filtered eyes from 37 PACG patients with mean age of 62.1±10.4 years were consecutively enrolled. All patients had visually significant cataracts and phacoemulsification was performed at least 12 months after trabeculectomy. Visual acuity, IOP and the number of glaucoma medications were recorded preoperatively, and 1, 3, 6 and 12 months after surgery...
January 2013: Journal of Ophthalmic & Vision Research
Mohammad Reza Akbari, Leila Hosseini Alhashemi, Alireza Keshtcar Jafari, Bahram Eshraghi, Ghasem Fakhraie
A 67 year old woman presented with her left eye fixed in adduction and infraduction. She had previous complicated strabismus surgery 18 years ago with a report of intraoperative loss of left medial rectus (MR) muscle (not retrieved at the time of surgery). An Orbital MRI of the left eye showed reattachment of the MR muscle to the globe and an axially enlarged globe associated with inferior displacement of the lateral rectus and nasal displacement of the superior rectus muscles. In ultrasonography the axial lengths were 24...
2013: Binocular Vision & Strabology Quarterly, Simms-Romano's
Sasan Moghimi, Hamidreza Torabi, Ghasem Fakhraie, Nariman Nassiri, Massood Mohammadi
PURPOSE: To compare the intraocular pressures (IOP) and ocular pulse amplitudes (OPAs) in patients with primary open-angle glaucoma (POAG) and pseudoexfoliation glaucoma (PXG), and to evaluate ocular and systemic factors associated with the OPA. MATERIALS AND METHODS: In this prospective study, on 28 POAG and 30 PXG patients, IOP was measured with the Goldmann applanation tonometry (GAT) and the Pascal dynamic contour tonometry (DCT). Other measurements included central corneal thickness (CCT), vertical cup-to-disc ratio (CDR), and systolic and diastolic blood pressure...
April 2013: Middle East African Journal of Ophthalmology
Sasan Moghimi, Mehdi Zandian, Golshan Latifi, Heydar Amini, Yadollah Eslami, Reza Zarei, Ghasem Fakhraie, Kouros Nouri-Mahdavi
PURPOSE: To explore changes in central macular thickness (CMT) after a two-month period of glaucoma therapy with topical latanoprost after uneventful phacoemulsification. METHODS: Forty-one eyes of 31 patients with primary open angle or pseudoexfoliative glaucoma who required glaucoma medications after cataract surgery were prospectively enrolled. All eyes had undergone uneventful phacoemulsification with intraocular lens implantation at least 4 months before initiation of latanoprost...
October 2012: Journal of Ophthalmic & Vision Research
Sasan Moghimi, Zakieh Vahedian, Ghasem Fakhraie, Reza Ghaffari, Yadollah Eslami, Mahmood Jabarvand, Reza Zarei, Massood Mohammadi, Shan Lin
PURPOSE: To evaluate ocular biometric parameters in different subtypes of angle-closure disease in the Iranian population and compare them with normal eyes. DESIGN: Prospective, cross-sectional. METHODS: In this clinic-based study, 189 eyes of 154 patients consisting of 40 acute angle-closure glaucoma (AACG) eyes, 40 fellow eyes of AACG, 42 chronic angle-closure glaucoma (CACG) eyes, 40 primary angle-closure suspect (PACS) eyes, and 27 normal eyes underwent complete examination including gonioscopy, A-scan biometry, and anterior segment optical coherence tomography...
April 2013: American Journal of Ophthalmology
Yadollah Eslami, Golshan Latifi, Sasan Moghimi, Reza Ghaffari, Ghasem Fakhraie, Reza Zarei, Mahmood Jabbarvand, Massood Mohammadi, Shan Lin
BACKGROUND: To compare the anatomic effects of phacoemulsification (Phaco) versus combined phacoemulsification and viscogonioplasty (Phaco-VGP) on drainage angle status in primary angle-closure glaucoma (PACG) using anterior segment optical coherence tomography (AS-OCT). DESIGN: Prospective, randomized clinical trial. PARTICIPANTS: Sixty-seven eyes of 57 patients with the diagnosis of PACG. METHOD: Patients were randomized to undergo Phaco alone (33 eyes) or Phaco-VGP (34 eyes)...
May 2013: Clinical & Experimental Ophthalmology
Sasan Moghimi, Aliasghar Ahmadraji, Hamed Sotoodeh, Khosro Sadeghniat, Maryam Maghsoudipour, Ghasem Fakhraie, Golshan Latifi, Nariman Nassiri, Joann A Giaconi
OBJECTIVE: To investigate the prevalence of glaucoma, visual field abnormalities, as well as changes in retinal nerve fiber layer in patients with obstructive sleep apnea syndrome (OSAS). METHODS: In this cross-sectional study, 51 patients with OSAS were included. Based on apnea hypopnea index (AHI), there were 26, 6 and 19 cases of severe (AHI⩾30), moderate (15⩽AHI<30), and mild (5⩽AHI<15) OSAS, respectively. The control group was matched for age, sex and body mass index...
January 2013: Sleep Medicine
Golshan Latifi, Sasan Moghimi, Yadollah Eslami, Ghasem Fakhraie, Reza Zarei, Shan Lin
Purpose. To evaluate the anatomic effects of phacoemulsification on drainage angle status in primary angle closure glaucoma (PACG) using anterior segment optical coherence tomography (AS-OCT). Methods. A total of 62 eyes of 58 patients underwent cataract surgery in Farabi Rye Hospital, Tehran, Iran. Patients were examined postoperatively on day 1, week 1, and week 6. Indentation gonioscopy and AS-OCT were performed preoperatively and at 6 weeks after surgery. Main outcome measures were angle and anterior segment parameters by AS-OCT and amount of peripheral anterior synechiae (PAS) by gonioscopy...
January 21, 2013: European Journal of Ophthalmology
Yadolla Eslami, Massood Mohammadi, Ghasem Fakhraie, Reza Zarei, Sasan Moghimi
PURPOSE: To report the efficacy and safety of Ahmed glaucoma valve (AGV) insertion into the ciliary sulcus in pseudophakic/aphakic patients. PATIENTS AND METHODS: A chart review was done on patients with uncontrolled glaucoma, who underwent AGV implantation with tube inserted into the ciliary sulcus. Baseline intraocular pressure (IOP) and number of medications were compared with that of postoperative follow-up visits. Surgical success was defined as last IOP <21 mm Hg and 20% reduction in IOP, without further surgery for complications or glaucoma control, and without loss of light perception...
February 2014: Journal of Glaucoma
Yadollah Eslami, Massood Mohammadi, Mehdi Khodaparast, Elham Rahmanikhah, Reza Zarei, Sasan Moghimi, Ghasem Fakhraie
The purpose of this study was to describe the results of a new modification of the trabeculectomy technique, sutureless tunnel trabeculectomy without peripheral iridectomy (PI), in a group of patients with chronic open-angle glaucoma (COAG). Patients with uncontrolled COAG who were candidates for trabeculectomy underwent sutureless tunnel trabeculectomy without PI. Patients were examined before surgery and at 1, 3, 6 and 12 months after surgery. Pre- and post-operative data including intraocular pressure (IOP), visual acuity, number of anti-glaucoma medications and intraoperative and post-operative complications were recorded...
October 2012: International Ophthalmology
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