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JOURNAL ARTICLE
Ayoub Tavakolian, Seyed Hassan Ashrafi Shahri, Mohammad Ali Jafari, Elham Pishbin, Hamid Zamani Moghaddam, Mahdi Foroughian, Hamidreza Reihani
Introduction: The COVID-19 pandemic has been considered an international problem. This study aimed to survey the demographic and clinical characteristics of the deceased COVID-19 patients. Methods: The present cross-sectional study was performed on all deceased COVID-19 patients who died in Imam Reza Hospital, Mashhad, Iran, from March 20, 2020, to September 23, 2021. Their data, including age, gender, complaints, and clinical symptoms at the time of admission, as well as information at the time of death (hour, shift, holiday/non-holiday) were analyzed and reported...
2022: Archives of Academic Emergency Medicine
#22
JOURNAL ARTICLE
Fatemeh Tanhaye Kalate Sabz, Fatemeh Sadat Amjadi, Zahra Zandieh, Elham Hosseini, Reza Aflatoonian, Maryam Tabatabaei, Masoud Mohammadian, Mahnaz Ashrafi
Poor sperm quality in oligoasthenoteratospermia patients negatively affects assisted reproductive technology outcomes. Therefore, the development of sperm media is necessary to improve sperm parameters. This study investigated the effect of GM-CSF via PI3K/AKT pathway on sperm quality in OAT patients. Semen samples were collected from 20 OAT patients, and each sample was divided into two groups: Experiment and Control. In the experimental group, the samples were incubated with medium containing GM-CSF, and control samples were incubated without GM-CSF...
August 2022: Andrologia
#23
Mahmoud Reza Ashrafi, Elham Pourbakhtyaran, Mohammad Rohani, Bita Shalbafan, Ali Reza Tavasoli, Sareh Hosseinpour, Maryam Rasulinezhad, Zahra Rezaei, Ali Zare Dehnavi, Seyyed Mohammad Mahdi Hosseiny, Roya Haghighi, Homa Ghabeli, Morteza Heidari
Autosomal recessive cerebellar ataxias are a group of heterogeneous early-onset progressive disorders that some of them are treatable. We performed a 4-year follow-up for 25 patients who had treatable ataxia. According to our study, patients would benefit from early detection of treatable ataxia, close observation, and follow-up.
April 2022: Clinical Case Reports
#24
JOURNAL ARTICLE
Fatemeh Nikmard, Elham Hosseini, Mehrdad Bakhtiyari, Mahnaz Ashrafi, Fardin Amidi, Reza Aflatoonian
BACKGROUND: Melatonin, as a free radical scavenger exhibiting genomic actions, regulates the antioxidant genes expression and apoptosis mechanisms. In polycystic ovary syndrome (PCOS) patients, an imbalance between free radicals and antioxidants in follicular fluid leads to oxidative stress, aberrant folliculogenesis, and intrinsic defects in PCOS oocytes. In this experimental mouse model study, oocytes of PCOS and the control groups were cultured in different melatonin concentrations (10- 5 , 10- 6 , and 10- 7 M) to investigate the expression of oocyte maturation-related genes (Gdf9/Bmp15), antioxidant-related genes (Gpx1/Sod1), apoptotic biomarkers (Bcl2/Bax) and total intracellular ROS levels...
January 20, 2022: Journal of Ovarian Research
#25
JOURNAL ARTICLE
Ali Reza Tavasoli, Elmira Haji Esmaeil Memar, Mahmoud Reza Ashrafi, Seyed Mohammad Mahdi Hosseini, Roya Haghighi, Homa Ghabeli, Elham Pourbakhtyaran, Maryam Rasoulinezhad, Pouria Mohammadi, Morteza Heidari
Autosomal recessive microcephaly is a rare clinical condition, which is characterized by reduced brain size that can be associated with delayed intellectual ability, developmental delay, and seizure. In this study, we describe two siblings with microcephaly: a 12-year-old girl with primary microcephaly, and a 7-year-old boy with secondary microcephaly, whose episodes of seizure and neurodevelopmental regression started at 6 years and 6 months of age, respectively. The interesting finding in these siblings was two different presentations of the same variant: one case with primary and one case with secondary microcephaly...
January 4, 2022: Journal of Molecular Neuroscience: MN
#26
JOURNAL ARTICLE
Nazgol Motamed-Gorji, Ali Jafari, Seyed Farzad Mohammadi, Elham Ashrafi, Roqayeh Aliyari, Mohammad Hassan Emamian, Hassan Hashemi, Akbar Fotouhi
CLINICAL RELEVANCE: Posterior corneal astigmatism has an important role in diagnosis and treatment of astigmatism, but it is usually overlooked. BACKGROUND: This cross-sectional study aimed to investigate the distribution of posterior corneal astigmatism (PCA) and its associated factors in a middle-aged population that participated in the Shahroud Eye Cohort Study (ShECS) phase II. METHODS: Anterior corneal astigmatism (ACA) and PCA values were measured using rotating Scheimpflug System (Pentacam HR, Oculus)...
November 9, 2021: Clinical & Experimental Optometry: Journal of the Australian Optometrical Association
#27
RANDOMIZED CONTROLLED TRIAL
Samaneh Aghajanpour, Elham Hosseini, Elham Amirchaghmaghi, Zahra Zandieh, Fatemehsadat Amjadi, Azar Yahyaei, Zahra Zolfaghari, Khashayar Aflatoonian, Mahnaz Ashrafi, Reza Aflatoonian
BACKGROUND: Endometrial scratching (ES) has been proposed as a potential treatment for implantation improvement in unexplained repeated implantation failure (uRIF) patients, however, little is known about its exact molecular mechanisms. OBJECTIVE: This randomized controlled trial (RCT) was conducted on twenty uRIF patients to investigate the expression of innate and adaptive immune signaling genes after ES. METHODS: Ten uRIF patients in the intervention (twice endometrial sampling in follicular and luteal phases) and 10 uRIF patients in the control group (only luteal phase sampling) were randomly enrolled...
November 2021: Journal of Reproductive Immunology
#28
RANDOMIZED CONTROLLED TRIAL
Zohreh Ghaem Far, Siavash Babajafari, Javad Kojuri, Salman Mohammadi, Mehran Nouri, Pouya Rostamizadeh, Mohammad Hossein Rahmani, Mohsen Azadian, Elham Ashrafi-Dehkordi, Alireza Zareifard, Reza Golchin Vafa, Seyed Mohammad Mazloomi
Systemic arterial hypertension is an independent risk factor for coronary heart disease, stroke, heart failure, and chronic kidney diseases. Spirulina is microalgae with nutritious ingredients and has potential attenuating effects on chronic diseases including hypertension. Spirulina can be added to food products in order to develop functional foods. The aim of this study was to assess the effects of 8-week consumption of a salad dressing containing 2 g of spirulina platensis powder versus a placebo dressing on patients with hypertension...
November 2021: Phytotherapy Research: PTR
#29
JOURNAL ARTICLE
Farzad Ashrafi, Davood Ommi, Alireza Zali, Sina Khani, Amirali Soheili, Mehran Arab-Ahmadi, Behdad Behnam, Shabnam Nohesara, Farbod Semnani, Alireza Fatemi, Mehri Salari, Reza Jalili Khoshnood, Mohammad Vahidi, Niloofar Ayoobi-Yazdi, Saeed Hosseini Toudeshki, Elham Sobhrakhshankhah
INTRODUCTION: COVID-19 might present with other seemingly unrelated manifestations; for instance, neurological symptoms. This study aimed to evaluate the neurologic manifestations and their correlated factors in COVID-19 patients. METHODS: This retrospective observational study was conducted from March 17, 2020 to June 20, 2020 in a tertiary hospital in Iran. The study population consisted of adult patients with a positive result for COVID-19 real-time reverse transcriptase polymerase chain reaction (RT-PCR) using nasopharyngeal swabs...
2021: Archives of Academic Emergency Medicine
#30
JOURNAL ARTICLE
Gholamreza Roshandel, Jacques Ferlay, Ali Ghanbari-Motlagh, Elham Partovipour, Fereshteh Salavati, Kimia Aryan, Gohar Mohammadi, Mostafa Khoshaabi, Alireza Sadjadi, Masoud Davanlou, Fereshteh Asgari, Hakimeh Abadi, Abbas Aghaei, Seyed-Vahid Ahmadi-Tabatabaei, Kazem Alizadeh-Barzian, Abbasali Asgari, Noorali Asgari, Soheyla Azami, Maria Cheraghi, Floria Enferadi, Masoumeh Eslami-Nasab, Jila Fakhery, Mohsen Farahani, Solmaz Farrokhzad, Mansooreh Fateh, Ali Ghasemi, Fatemeh Ghasemi-Kebria, Hajar Gholami, Arash Golpazir, Susan Hasanpour-Heidari, Narjes Hazar, Hosein Hoseini-Hoshyar, Mohsen Izadi, Mahdi Jahantigh, Ahmad Jalilvand, Seyed-Mehrdad Jazayeri, Yasan Kazemzadeh, Maryam Khajavi, Maryam Khalednejad, Marziyeh Khanloghi, Maryam Kooshki, Amineh Madani, Mahdi Mirheidari, Hosein Mohammadifar, Zeinab Moinfar, Yasaman Mojtahedzadeh, Ali Morsali, Rita Motidost-Komleh, Tahereh Mousavi, Maboobeh Narooei, Mohammad Nasiri, Sharareh Niksiar, Mehdi Pabaghi, Habibollah Pirnejad, Azadeh Pournajaf, Gita Pourshahi, Amir Rahnama, Bahman Rashidpoor, Zahra Ravankhah, Khadijeh Rezaei, Abbas Rezaianzadeh, Gholamreza Sadeghi, Mohammad Salehifar, Athareh Shahdadi, Mehraban Shahi, Farrokh Sharifi-Moghaddam, Roya Sherafati, Ali Soleimani, Maryam Soltany-Hojatabad, Mohammad-Hossein Somi, Sohrab Yadolahi, Majid Yaghoubi-Ashrafi, Aliakbar Zareiyan, Hossein Poustchi, Kazem Zendehdel, Afshin Ostovar, Ghasem Janbabaei, Alireza Raeisi, Elisabete Weiderpass, Reza Malekzadeh, Freddie Bray
Policymakers require estimates of the future number of cancer patients in order to allocate finite resources to cancer prevention, treatment and palliative care. We examine recent cancer incidence trends in Iran and present predicted incidence rates and new cases for the entire country for the year 2025. We developed a method for approximating population-based incidence from the pathology-based data series available nationally for the years 2008 to 2013, and augmented this with data from the Iranian National Population-based Cancer Registry (INPCR) for the years 2014 to 2016...
August 1, 2021: International Journal of Cancer. Journal International du Cancer
#31
JOURNAL ARTICLE
Reza Jafari, Seyed Abdolvahab Taghavi, Elham Amirchaghmaghi, Reza Salman Yazdi, Leili Karimian, Mahnaz Ashrafi, Reza Aflatoonian
BACKGROUND: Inflammatory responses within the peritoneal cavity may result in endometrial dysfunction in women with endometriosis. The true causes of this disease remain poorly understood. It is hypothesized that downstream toll-like receptors (TLRs) inflammatory cytokines in response to pathogens may be associated with endometriosis. So, this study was aimed at evaluating the expression of TLRs signaling and endometriosis-associated inflammatory responses. METHODS: Totally, 20 infertile endometriosis patients and 20 normal women undergoing controlled ovarian stimulation were enrolled...
October 2020: Journal of Reproduction & Infertility
#32
JOURNAL ARTICLE
Sepideh Jamali, Elham Ashrafi, Seyed Farzad Mohammadi
No abstract text is available yet for this article.
July 2020: Journal of Diabetes Science and Technology
#33
JOURNAL ARTICLE
Elham Ashrafi, Sepideh Jamali, Seyed Farzad Mohammadi, Parinaz Mehdipoor
PURPOSE: To determine the national and subnational prevalence of amblyopia and the respective provincial distribution and trend during 1990-2018 in Iran. METHODS: Amblyopia data retrieved from 26 original studies, systematic reviews, Data has been cleaned by STATA and a linear mixed effect spatio-temporal model was used to calculate Gaussian process regression mean functions. Using a Bayesian approach, by pooling empirical data based on the assumed prior, a posterior distribution obtained for age and sex specific prevalence prediction nationally during the study time and provincially...
April 2020: Journal of Optometry
#34
JOURNAL ARTICLE
Shirin Farahyar, Samira Izadi, Elham Razmjou, Mehraban Falahati, Maryam Roudbary, Mahtab Ashrafi-Khozani, Saham Ansari, Azam Fattahi, Zahra Ghahri-Mobaser, Maryam Rahimi
The Candida ( C .) albicans complex includes C. albicans , C. dubliniensis , C. stellatoidea, and C. africana , with the last mentioned as an important emerging agent of vulvovaginal candidiasis (VVC). The aim of the study was to identify C. africana and C. dubliniensis and assess their drug susceptibility in vaginitis. One-hundred Candida isolates of the C. albicans complex from women diagnosed with vaginitis and from vaginal samples in the culture collection of a medical mycology laboratory were examined...
March 2020: Heliyon
#35
JOURNAL ARTICLE
Mahmoud Reza Ashrafi, Hossein Mohebbi, Mahmoud Mohamadi, Elham Azizi, Gholam Reza Zamani, Alireza Tavasoli, Reza Shervin Badv, Firozeh Hosseini
Objective: One of the difficulties to conduct electroencephalography (EEG) in pediatric patient population is that they are not always cooperative during the procedure. Different medications are used to induce sedation during EEG recording. In order to find a medication with the least adverse effects and high efficacy, the current study aimed at comparing clonidine and chloral hydrate as a premedication prior to EEG recording in pediatric population. Materials & Methods: A prospective, randomized, single-blinded, controlled trial was conducted on 198 children (9 to 156 months old) to investigate the sedative and adverse effects of clonidine and chloral hydrate...
2020: Iranian Journal of Child Neurology
#36
JOURNAL ARTICLE
Alireza Lashay, Elham Delrish, Elham Ashrafi, Morteza Movassat, Fahimeh Asadi-Amoli, Rassoul Dinarvand, Mojtaba Abrishami
BACKGROUND AND OBJECTIVE: To evaluate the safety and bioavailability of complete and half-dose of intravitreal ziv-aflibercept (IVZ) in an experimental model. MATERIALS AND METHODS: Thirty-two eyes of 16 male rabbits received one IVZ injection under anesthesia and the operating microscope. All right and left eyes received 1,250 μg/0.05 mL and 625 μg/0.05 mL of ziv-aflibercept, respectively. Then, rabbits were randomly allocated to four groups (four rabbits in each group)...
December 1, 2019: Ophthalmic Surgery, Lasers & Imaging Retina
#37
JOURNAL ARTICLE
Seyed-Farzad Mohammadi, Cyrus Alinia, Ebrahim Ghaderi, Alireza Lashay, Mahmoud Jabbarvand, Elham Ashrafi, Naser Nourmohammadi, Saeid Shahraz
Background: Due to lack of information about ophthalmic economics in Iran, health policy makers unable to distribute resources optimally in terms of efficiency and equity. Therefore, we estimated the total and eye care utilization, out-of-pocket expenditures, and its association with social determinants of health in Iran in 2015. Methods: A multi-stage population-based, cross-sectional study in a random sample aged 50 yr or older in Kurdistan Province, Northwest Iran was used...
July 2019: Iranian Journal of Public Health
#38
JOURNAL ARTICLE
Elham Hosseini, Maryam Shahhoseini, Parvaneh Afsharian, Leila Karimian, Mahnaz Ashrafi, Fereshteh Mehraein, Reza Afatoonian
INTRODUCTION: In this study, the global DNA methylation, histone acetylation and methylation levels of cumulus cells (CCs) in infertile polycystic ovary syndrome (PCOS) patients and the correlation of these epigenetic modifications with the expression of the ovarian aromatase gene (as an important marker in the etiology of PCOS) were investigated. MATERIAL AND METHODS: A cross-sectional study was conducted on 24 patients (12 PCOS patients and 12 healthy women), who underwent ovarian stimulation...
July 2019: Archives of Medical Science: AMS
#39
JOURNAL ARTICLE
Gholamreza Roshandel, Ali Ghanbari-Motlagh, Elham Partovipour, Fereshteh Salavati, Susan Hasanpour-Heidari, Gohar Mohammadi, Mostafa Khoshaabi, Alireza Sadjadi, Masoud Davanlou, Seyed-Mohammad Tavangar, Hakimeh Abadi, Abasali Asgari, Mohamadreza Behrooz, Maria Cheraghi, Leila Danechin, Roya Dolatkhah, Floria Enferadi, Soodabeh Esshaghi, Mohsen Farahani, Solmaz Farrokhzad, Mansooreh Fateh, Siamak Vahedi, Arash Golpazir, Mahdieh Hasanzadeh, Narjes Hazar, Hosein Hoseini-Hoshyar, Mohsen Izadi, Ali Jafarnia, Mahdi Jahantigh, Ahmad Jalilvand, Mehrdad Jazayeri, Parvin Joola, Yasan Kazemzadeh, Maryam Khalednejad, Maryam Kooshki, Amineh Madani, Reza Malekpour-Afshar, Amir-Hossein Bayat, Zeinab Moinfar, Hosein Mohamadifar, Gholamhasan Mohamadzadeh, Rita Motidost-Komleh, Mahboobeh Narooei, Sharareh Niksiar, Habibollah Pirnejad, Azadeh Poornajaf, Gita Pourshahi, Amir Rahnama, Bahman Rashidpour, Zahra Ravankhah, Khadijeh Rezaei, Abbas Rezaeianzadeh, Gholamreza Sadeghi, Athar Shahdadi, Mehraban Shahi, Zahra Sharafi, Farroq Sharifi-Moghadam, Ali Soleimani, Maryam Soltany-Hojatabad, Zeinab Tahmasebi, Sohrab Yadolahi, Majid Yaghoubi-Ashrafi, Hamed Zandian, Aliakbar Zareiyan, Hossein Poustchi, Kazem Zendehdel, Afshin Ostovar, Ghasem Janbabaei, Alireza Reisi, Reza Malekzadeh
BACKGROUND: We aimed to report, for the first time, the results of the Iranian National Population-based Cancer Registry (INPCR) for the year 2014. METHODS: Total population of Iran in 2014 was 76,639,000. The INPCR covered 30 out of 31 provinces (98% of total population). It registered only cases diagnosed with malignant new primary tumors. The main sources for data collection included pathology center, hospitals as well as death registries. Quality assessment and analysis of data were performed by CanReg-5 software...
August 2019: Cancer Epidemiology
#40
JOURNAL ARTICLE
Elham Ashrafi, Seyed-Farzad Mohammadi, Marzieh Katibeh, Ebrahim Ghaderi, Cyrus Alinia, Naser Nourmohammadi, Alireza Lashay, Ramin Beiranvand, Mahsa Yousefpour Marzbali, Ali Sadeghi Tari
Purpose: To determine the magnitude and causes of blindness and visual impairment (VI) in Kurdistan, using the Rapid Assessment of Avoidable Blindness methodology. Methods: In this population-based cross sectional study, 99 clusters were selected through probability proportional to size sampling. Visual acuity (VA) was measured using a standard tumbling "E" chart. Ophthalmologists examined participants with VA < 6/18 in both eyes. The cause of VI in the better eye or the most treatable cause was considered as the primary cause of VI...
April 2019: Journal of Ophthalmic & Vision Research
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