keyword
https://read.qxmd.com/read/35750709/flat-irregular-pigment-epithelial-detachment-over-time-and-outcome-of-different-treatment-regimens
#21
JOURNAL ARTICLE
Nazanin Ebrahimiadib, Mohammadreza Mehrabi Bahar, Hamid Riazi-Esfahani, Elias Khalili Pour, Fariba Ghassemi, Hooshang Faghihi, Ahmad Mirshahi, Ramak Roohipourmoallai, Alireza Lashay, Alireza Mahmoudi, Kaveh Fadakar
To present long-term visual and structural outcome of treatment in two forms of flat irregular pigment epithelial detachment (FIPED): avascular (aFIPED) and vascularized (vFIPED) in eyes within pachychoroid spectrum. Prospective interventional case series. FIPED were classified into two subgroups; aFIPED and vFIPED based on OCTA. aFIPED underwent PDT, and vFIPED underwent either PDT, IVB, or combination of PDT&IVB. Vision, subretinal or intraretinal fluid, and choroidal biomarkers such as choroidal thickness, area, choroidal vascular index (CVI), and PED area were measured at baseline and last follow-up...
June 24, 2022: Scientific Reports
https://read.qxmd.com/read/35677620/near-infrared-confocal-reflectance-scanning-laser-ophthalmoscopy-slo-and-short-wavelength-autofluorescence-imaging-in-cystic-diabetic-macular-edema
#22
JOURNAL ARTICLE
Fariba Ghassemi, Fatemeh Bazvand, Houshang Faghihi, Ramak Roohipourmoallai, Maryam Masoumi, Sepide Jamali, Masoumeh Mohebbi, Siamak Sabour
Objective: To characterize results of short-wavelength autofluorescent (SW-AF) and near-infrared confocal reflectance scanning laser ophthalmoscopy (NIR-cR SLO) imaging in cystic diabetic macular edema (DME). Design: Cross-sectional study. Participants: 104 eyes from 52 naïve treatment patients with DME and mild to moderate nonproliferative diabetic retinopathy (NPDR) Methods: complete ocular examination, best-corrected visual acuity (BCVA), and imaging were performed...
2022: Journal of Ophthalmology
https://read.qxmd.com/read/35620369/ocular-manifestations-of-newly-diagnosed-acute-leukemia-patients
#23
JOURNAL ARTICLE
Reza Mirshahi, Fariba Ghassemi, Leili Koochakzadeh, Mohammad Faranoush, Zahra Ghomi, Azim Mehrvar, Seyed Asadollah Mousavi, Seyyed Reza Safaee Nodehi
Purpose: To present primary ocular manifestations in acute leukemia. Methods: This cross-sectional descriptive hospital-based study evaluated all newly diagnosed leukemia patients of three referral hospitals of Tehran University of Medical Sciences in 2015-2016 and Mahak Hospital in Tehran in 2017. Exclusion criteria included the patients with the previous history of chemotherapy, cases of relapsing disease, and the patients with a history of ocular disease or other systemic conditions with ophthalmic manifestations...
January 2022: Journal of Current Ophthalmology
https://read.qxmd.com/read/35461303/management-of-primary-choroidal-lymphoma-presenting-as-extensive-serous-retinal-detachment-and-salmon-patch-of-bulbar-conjunctiva-a-case-report
#24
JOURNAL ARTICLE
Zahra Mahdizad, Elias Khalili Pour, Mohammadreza Mehrabi Bahar, Amirreza Esfandiari, Babak Masoomian, Hamid Riazi-Esfahani, Ahmad Mirshahi, Fariba Ghassemi
BACKGROUND: We describe the outcome of ultra-low-dose radiotherapy plus intravitreal methotrexate and rituximab injections for a patient with primary choroidal lymphoma who presented with nodular conjunctival salmon patches and extensive serous retinal detachment. CASE PRESENTATION: A 34-year-old Iranian man presented with a nodular patch of bulbar conjunctiva in the right eye, and 1+ vitritis. A nearly complete shallow serous retinal detachment, retinal folds, and multifocal yellow choroidal infiltrates were seen during a fundus examination of the right eye...
April 24, 2022: Journal of Medical Case Reports
https://read.qxmd.com/read/35128196/five-year-experience-in-treatment-of-retinoblastoma-with-intra-arterial-chemotherapy-a-single-center-analysis
#25
JOURNAL ARTICLE
Fariba Ghassemi, Shima Dehghani, Raziyeh Mahmoudzadeh, Alireza Khodabandeh, Hossein Ghanaati, Gholamreza Termehchi
PURPOSE: To report our 5-year experience in treating retinoblastoma (RB) with intra-arterial chemotherapy (IAC) as a primary or secondary therapy, without adjuvant intravitreal chemotherapy. METHODS: A retrospective study was conducted on 70 eyes with intraocular RB that were treated with primary or secondary IAC from December 2010-2015. Demographic characteristics, clinical features, tumor control, and treatment complications were compared and reported. RESULTS: Thirty-seven eyes had received IAC as a secondary therapy after failed/incomplete response to systemic chemotherapy, and 33 eyes had received IAC as a primary treatment...
October 2021: Journal of Current Ophthalmology
https://read.qxmd.com/read/35104202/comparison-of-the-accuracy-of-anterior-segment-optical-coherence-tomography-and-ultrasound-biomicroscopy-in-localizing-rectus-muscle-insertions
#26
JOURNAL ARTICLE
Arash Mirmohammadsadeghi, Nikoo Hamzeh, Fariba Ghassemi, Mohammad Reza Akbari
PURPOSE: To compare the accuracy of anterior segment optical coherence tomography (AS-OCT) and ultrasound biomicroscopy (UBM) in localizing rectus muscle insertions. METHODS: The study was performed on 27 patients (39 rectus muscles) who required primary or secondary surgery. Using caliper function in the AS-OCT and UBM software, the distance from the insertion site to the anterior chamber angle was measured. The actual muscle insertion distance from limbus was considered as the measured distance plus 1 mm...
February 1, 2022: Journal of Binocular Vision and Ocular Motility
https://read.qxmd.com/read/34980024/the-quantitative-measurements-of-choroidal-thickness-and-volume-in-diabetic-retinopathy-using-optical-coherence-tomography-and-optical-coherence-tomography-angiography-correlation-with-vision-and-foveal-avascular-zone
#27
JOURNAL ARTICLE
Fariba Ghassemi, Sahar Berijani, Ameneh Babeli, Houshang Faghihi, Alireza Gholizadeh, Siamak Sabour
BACKGROUND: To represent choroidal thickness (CT) and choroidal volume (CV) databases in diabetic retinopathy (DR) patients and healthy control participants using optical coherence tomography (OCT) and enhanced depth imaging OCT (EDI-OCT). No study had evaluated CT at all main stages of diabetic retinopathy in a single study. METHODS: The study included 176 eyes from 93 patients (39-80 years old; 42% females) who were divided into three groups based on DR severity and normal control group: 39 eyes no DR, 64 eyes NPDR, 33 eyes PDR, and 40 eyes normal control...
January 3, 2022: BMC Ophthalmology
https://read.qxmd.com/read/34931150/sickle-cell-trait-presenting-as-unilateral-proliferative-retinopathy-and-macular-thinning-in-a-pregnant-woman
#28
Sepideh Ghods, Elias Khalili Pour, Hooshang Faghihi, Golnaz Gharehbaghi, Ahmad Mirshahi, Fariba Ghassemi, Bahman Inanloo, Hamid Riazi-Esfahani
Background: To report a case of a pregnant woman with sickle cell trait (SCT) who presented with unilateral proliferative sickle cell retinopathy. Case Presentation . A 26-year-old otherwise healthy pregnant woman presented with the complaint of visual loss in her left eye. The funduscopic examination showed vitreous hemorrhage, sea fan neovascularization, and pale optic disc. Optical coherence tomography revealed macular inner retinal layer thinning and foveal splaying (saucerization of the foveal pit)...
2021: Case Reports in Ophthalmological Medicine
https://read.qxmd.com/read/34727878/evaluation-of-radiation-maculopathy-after-treatment-of-choroidal-melanoma-with-ruthenium-106-using-optical-coherence-tomography-angiography
#29
JOURNAL ARTICLE
Ali Torkashvand, Hamid Riazi-Esfahani, Fariba Ghassemi, Elias Khalili Pour, Babak Masoomian, Mohammad Zarei, Kaveh Fadakar, Mojtaba Arjmand, Fereshteh Tayebi, Leila Ekradi, Hamid Abrishami Moghaddam, Tahereh Mahmoudi, Reihaneh Daneshmand, Hooshang Faghihi
BACKGROUND: To assess the impact of brachytherapy on macular microvasculature utilizing optical coherence tomography angiography (OCTA) in treated choroidal melanoma. METHODS: In this retrospective observational case series, we reviewed the recorded data of the patients with unilateral extramacular choroidal melanoma treated with ruthenium - 106 (106 Ru) plaque radiotherapy with a follow-up period of more than 6 months. Automatically measured OCTA retinal parameters were analysed after image processing...
November 2, 2021: BMC Ophthalmology
https://read.qxmd.com/read/34600586/quantification-of-macular-perfusion-in-healthy-children-using-optical-coherence-tomography-angiography
#30
JOURNAL ARTICLE
Fariba Ghassemi, Vahid Hatami, Farhad Salari, Fatemeh Bazvand, Hadi Shamouli, Masoumeh Mohebbi, Siamak Sabour
BACKGROUND: This study aimed at defining the variance of vessel density (VD) characteristics in the macula of children with normal eyes. METHODS: This was a cross-sectional study in which subjects with normal eyes aged 3-18 years were enrolled. The macula was scanned by optical coherence tomography angiography (OCTA). Four age groups as under 7 years, 7-10 years, 11-14 years and more than 14 years of age were defined. The influences of age, gender, and body mass index on VD were analyzed...
October 2, 2021: International Journal of Retina and Vitreous
https://read.qxmd.com/read/34555122/choroidal-features-in-flat-irregular-pigment-epithelial-detachment-associated-with-chronic-central-serous-chorioretinopathy-avascular-versus-vascularized
#31
JOURNAL ARTICLE
Hooshang Faghihi, Alireza Mahmoudi, Elias Khalili Pour, Nazanin Ebrahimiadib, Kaveh Fadakar, Fariba Ghassemi, Ahmad Mirshahi, Alireza Khodabande, Hassan Khojasteh, Fatemeh Bazvand, Mohammadreza Mehrabi Bahar, Hamid Riazi-Esfahani
PURPOSE: To investigate the differences in the choroidal biomarkers between two forms of flat irregular pigment epithelial detachment (FIPED): avascular (aFIPED) and vascularized (vFIPED) in eyes with chronic central serous chorioretinopathy (CSC). MATERIALS AND METHODS: Enhanced depth imaging optical coherence tomography (EDI-OCT) was done in eyes with FIPED correlated to chronic CSC, fellow eyes, and also in healthy eyes from gender- and age-matched subjects. Eyes with FIPED were classified into two subgroups based on optical coherence tomography angiography (OCTA) findings: vFIPED and aFIPED...
2021: PloS One
https://read.qxmd.com/read/34468831/alterations-in-choroidal-vascular-parameters-following-panretinal-photocoagulation-using-enhanced-depth-imaging-optical-coherence-tomography-in-diabetic-retinopathy
#32
JOURNAL ARTICLE
Ahmad Mirshahi, Kaveh Fadakar, Reza Mirshahi, Elias Khalili Pour, Nazanin Ebrahimiadib, Fariba Ghassemi, Hassan Khojasteh, Fatemeh Bazvand, Sepideh Ghods, Hamid Riazi-Esfahani, Hooshang Faghihi
PURPOSE: To investigate the alteration of choroid in patients with very severe non-proliferative diabetic retinopathy (NPDR) or early proliferative diabetic retinopathy (PDR) following panretinal photocoagulation (PRP). METHODS: Thirty-nine eyes of 21 patients with very severe non-proliferative diabetic retinopathy (NPDR) (19 eyes) and early proliferative diabetic retinopathy (PDR) (20 eyes) were recruited. Enhanced-depth imaging optical coherence tomography at baseline, 1, and 6 months after PRP was employed to measure choroidal parameters including total choroidal area (TCA) and choroidal vascular index (CVI)...
September 1, 2021: Graefe's Archive for Clinical and Experimental Ophthalmology
https://read.qxmd.com/read/34336323/intra-arterial-chemotherapy-new-hope-for-adult-retinoblastoma-treatment-a-case-report-and-brief-review
#33
Hamid Riazi-Esfahani, Babak Masoomian, Fariba Ghassemi
Background: Adult retinoblastoma (RB) is a rare intraocular tumor, leading to delayed diagnosis and, eventually, enucleation of the involved eyes. Therefore, this diagnosis should be considered if attributable signs and symptoms occurred. Here, the authors report a case of an adult group D RB, treated successfully with intra-arterial chemotherapy (IAC) as primary treatment followed by cryotherapy. The authors briefly review the literature on the prognosis and management of adult RB. Case Presentation ...
2021: Case Reports in Ophthalmological Medicine
https://read.qxmd.com/read/34250764/ocular-safety-of-repeated-intravitreal-injections-of-carboplatin-and-digoxin-a-preclinical-study-on-the-healthy-rabbits
#34
JOURNAL ARTICLE
Alireza Khodabande, Fariba Ghassemi, Fahimeh Asadi Amoli, Hamid Riazi-Esfahani, Raziyeh Mahmoudzadeh, Mohammad Mehrpour, Niloufar Valipour
To evaluate the ocular safety of intravitreal carboplatin and digoxin injections as a new intravitreal chemotherapy option for retinoblastoma tumor vitreous seeds. Eighteen rabbits were divided randomly into three groups to receive intravitreal injection of Digoxin (6 rabbits), Carboplatin (7 rabbits), or Saline (5 rabbits). In every group, one eye randomly treated with 10 µg Digoxin in 0.1 cc or 1 µg Carboplatin or Saline, and the contralateral eye was considered as the control. All groups underwent three consecutive injections of the drugs with 1-week intervals...
August 2021: Pharmacology Research & Perspectives
https://read.qxmd.com/read/34221526/a-new-rapidly-growing-dome-shaped-choroidal-lesion-in-an-eye-with-treated-retinoblastoma
#35
Babak Masoomian, Maria Pefkianaki, Fariba Ghassemi, Hamid Riazi-Esfahani
BACKGROUND: To describe an extensive untreatable choroidal metastasis by retinoblastoma in the treated patient which was clinically indistinguishable from regular tumor recurrence. METHODS: A 24-month-old girl without a family history of retinoblastoma (RB) was discovered to have group C RB in her right eye and group D in her left eye. The patient received 12 cycles of intravenous chemotherapy, intra-arterial chemotherapy (IAC), and intravitreal chemotherapy for the left eye and focal adjuvant therapy (laser thermotherapy and cryotherapy) for both eyes...
2021: Case Reports in Ophthalmological Medicine
https://read.qxmd.com/read/33595607/giant-papillary-and-peripapillary-staphyloma
#36
Fariba Ghassemi, Sima Sheikhghomi, Elias Khalilipour
No abstract text is available yet for this article.
February 1, 2021: JAMA Ophthalmology
https://read.qxmd.com/read/33593444/multimodal-imaging-for-paracentral-acute-maculopathy-the-diagnostic-role-of-en-face-oct
#37
JOURNAL ARTICLE
Hamid Riazi-Esfahani, Elias Khalili Pour, Kaveh Fadakar, Nazanin Ebrahimiadib, Fariba Ghassemi, Ramin Nourinia, Hassan Khojasteh, Behnoosh Attarian, Hooshang Faghihi, Hamid Ahmadieh
BACKGROUND: To describe the features of multimodal imaging and the diagnostic role of en face OCT in the paracentral acute middle maculopathy (PAMM) spectrum. METHODS: In this observational case series, 5 eyes of 5 patients with acute PAMM were identified. Demographic characteristics as well as data regarding the underlying disease, presenting visual acuity (VA) and ophthalmic examination results were recorded. All patients underwent multimodal imaging within 3 days after symptom onset...
February 16, 2021: International Journal of Retina and Vitreous
https://read.qxmd.com/read/33579225/quantitative-assessment-of-vascular-density-in-diabetic-retinopathy-subtypes-with-optical-coherence-tomography-angiography
#38
JOURNAL ARTICLE
Fariba Ghassemi, Kaveh Fadakar, Sahar Berijani, Ameneh Babeli, Alireza Gholizadeh, Siamak Sabour
BACKGROUND: Quantitative assessment of vascular density (VD) of retinal and choriocapillaris (CC) in various stages of diabetic retinopathy (DR) using spectral domain optical coherence tomography angiography (SD OCTA). METHODS: 188 eyes of 97 participants were recruited in this cross-sectional study. The macular OCTA (3x3mm) scan was performed and the computer algorithm assessed VD at the level of superficial capillary plexus (SCP), deep capillary plexus (DCP) and CC...
February 12, 2021: BMC Ophthalmology
https://read.qxmd.com/read/33520125/intraocular-injection-of-stivant%C3%A2-a-biosimilar-to-bevacizumab-a-case-series
#39
JOURNAL ARTICLE
Ahmad Mirshahi, Alireza Lashay, Hamid Riazi-Esfahani, Nazanin Ebrahimiadib, Hassan Khojasteh, Fariba Ghassemi, Fatemeh Bazvand, Alireza Khodabande, Ramak Roohipour, Elias Khalili Pour, Hooshang Faghihi
PURPOSE: To report the results of intravitreal injection of a bevacizumab biosimilar called StivantⓇ. METHODS: This prospective interventional case series was conducted on eyes with neovascular age-related macular degeneration (nAMD), retinal vein occlusion (RVO), and diabetic macular edema (DME). StivantⓇ was injected in three consecutive months and changes in best-corrected visual acuity (BCVA) and central macular thickness (CMT) were measured at baseline and monthly up to one month after the third injection...
January 2021: Journal of Ophthalmic & Vision Research
https://read.qxmd.com/read/33453276/efficacy-of-topotecan-nanoparticles-for-intravitreal-chemotherapy-of-retinoblastoma
#40
JOURNAL ARTICLE
Elham Delrish, Mahmoud Jabbarvand, Fariba Ghassemi, Fahimeh Asadi Amoli, Fatemeh Atyabi, Alireza Lashay, Masoud Soleimani, Leila Aghajanpour, Rassoul Dinarvand
Retinoblastoma (Rb) is the most common intraocular malignancy in children that accounts for approximately 4% of all pediatric malignancies. Since chemotherapy is a widely practiced treatment for Rb, there is a growing interest in developing new and effective drugs to overcome systemic and local side effects of chemotherapy to improve the quality of life and increase the chances of survival. This study sought to fabricate thiolated chitosan nanoparticles containing topotecan (TPH-TCs-NPs) with a view of enhancing drug loading and release control...
March 2021: Experimental Eye Research
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