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Fariba Ghassemi

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https://www.readbyqxmd.com/read/28428970/changes-in-anterior-segment-parameters-following-pars-plana-vitrectomy-measured-by-ultrasound-biomicroscopy-ubm
#1
Zahra Ghomi, Fariba Ghassemi
Despite being a posterior segment ocular surgery, pars plana vitrectomy (PPV) may also affect anterior segment parameters. We aimed to investigate anterior segment alterations following PPV using ultrasound biomicroscopy (UBM) to visualize the structural anatomy of the eye. In this study, we enrolled phakic patients undergoing PPV (as the sole procedure). The anterior chamber depth, crystalline lens anterior-posterior (AP) diameter, anterior chamber angle, ciliary body dimensions, and integrity of the ciliary zonules and posterior capsule were assessed using UBM before and at least 3 months after PPV...
2017: Medical Hypothesis, Discovery and Innovation in Ophthalmology
https://www.readbyqxmd.com/read/28392901/mutation-analysis-of-connexin-50-gene-among-iranian-families-with-autosomal-dominant-cataracts
#2
Masoumeh Mohebi, Saeed Chenari, Abolfazl Akbari, Fariba Ghassemi, Mehran Zarei-Ghanavati, Ghasem Fakhraie, Nahid Babaie, Mansour Heidari
OBJECTIVES: Childhood cataract is a genetically heterogeneous eye disorder that results in visual impairment. The aim of this study was to identify the genetic mutations of connexin 50 gene among Iranian families suffered from autosomal dominant congenital cataracts (ADCC). MATERIALS AND METHODS: Families, having at least two members with bilateral familial congenital cataract, were selected for the study. Probands were evaluated by detailed ophthalmologist's examination, and the pedigree analysis was performed...
March 2017: Iranian Journal of Basic Medical Sciences
https://www.readbyqxmd.com/read/28367526/choroidal-thickness-in-idiopathic-macular-hole
#3
Reza Karkhaneh, Masoud Nikbakht, Fatemeh Bazvand, Afshin Kalantary Oskouei, Hamed Ghasemi, Fariba Ghassemi
PURPOSE: To measure the submacular choroidal thickness in eyes with idiopathic macular hole (IMH) compared with unaffected fellow eyes and normal control eyes. METHODS: In this single institutional retrospective comparative case-control study, 34 consecutive patients with IMH were included and compared with 30 normal age- and sex-matched eyes that were planned to have cataract surgery. The included eyes were divided into 4 groups: 41 eyes with IMH (A), 23 unaffected fellow eyes (B), 30 normal eyes (C), and 12 vitrectomized IMH eyes (D)...
March 2017: Journal of Current Ophthalmology
https://www.readbyqxmd.com/read/28299006/characteristics-of-macular-edema-in-behcet-disease-after-intravitreal-bevacizumab-injection
#4
Fariba Ghassemi, Sohrab Afshari Mirak, Hormoz Chams, Siamak Sabour, Mehdi Nilli Ahmadabadi, Fereidoun Davatchi, Farhad Shahram
PURPOSE: To investigate the effect of intravitreal bevacizumab (IVB) injection on macular edema (ME) secondary to Behcet's disease. METHODS: This prospective case series included 15 patients with bilateral ME due to Behcet's disease. Intravitreal bevacizumab was injected into the more severely involved eye; the contralateral eye was evaluated as the control. Patients were followed up with comprehensive ocular examination, optical coherence tomography, and fluorescein angiography (FA) for a minimum of 6 months by a single ophthalmologist...
January 2017: Journal of Ophthalmic & Vision Research
https://www.readbyqxmd.com/read/28223774/serum-hypercoagulability-states-in-coats-disease
#5
Fariba Ghassemi, Carol L Shields, Masoumeh Mohebbi, Mehdi Nili Ahmadabadi, Fatemeh Morsali, Siamak Sabour
PURPOSE: The purpose of this study was to investigate the serum hypercoagulability state and common viral and protozoan infections in Coats' disease versus a normal control group. MATERIALS AND METHODS: In this comparative case series, 22 consecutive patients with Coats' disease and 19 non-Coats' patients undergoing lensectomy for congenital, traumatic, or senile cataract between January 2011 and June 2014 were included. Laboratory data for hypercoagulability states and common viral and protozoan infections were investigated...
2017: Clinical Ophthalmology
https://www.readbyqxmd.com/read/27830204/outcomes-of-vitrectomy-membranectomy-and-internal-limiting-membrane-peeling-in-patients-with-refractory-diabetic-macular-edema-and-non-tractional-epiretinal-membrane
#6
Fariba Ghassemi, Fatemeh Bazvand, Ramak Roohipoor, Mehdi Yaseri, Narges Hassanpoor, Mohammad Zarei
PURPOSE: To evaluate the efficacy of vitrectomy, membranectomy, and internal limiting membrane (ILM) peeling on macular thickness and best corrected visual acuity (BCVA) in patients with refractory diffuse diabetic macular edema (DME) and non-tractional epiretinal membrane (NT-ERM). METHODS: This prospective interventional case series included eyes with refractory DME (central subfield macular thickness [CSMT] > 300 μm) after at least two intravitreal injections of bevacizumab (IVB) and one intravitreal injection of triamcinolone (IVT), and accompanying NT-ERM...
December 2016: Journal of Current Ophthalmology
https://www.readbyqxmd.com/read/27643804/correspondence
#7
Siamak Sabour, Fariba Ghassemi
No abstract text is available yet for this article.
October 2016: Retina
https://www.readbyqxmd.com/read/27413507/bilateral-presumed-tuberculous-choroiditis
#8
Naseh Mohammadi, Fariba Ghassemi, Esfandiar Shojaei, Pardis Moradnejad
PURPOSE: To describe a case of bilateral presumed tuberculous choroiditis which resolved promptly with a short course of antituberculous therapy. CASE REPORT: A 44-year-old lady presented with bilateral visual loss of 8 months'duration. Considering the presence of pan-uveitis, severe macular edema, multifocal leakage on fluorescein angiography, positive tuberculin skin test, and after excluding other diseases, she underwent anti-tuberculous therapy (ATT) for disseminated choroiditis due to presumed ocular tuberculosis...
April 2016: Journal of Ophthalmic & Vision Research
https://www.readbyqxmd.com/read/27306340/evaluation-of-sd-208-a-tgf-%C3%AE-ri-kinase-inhibitor-as-an-anticancer-agent-in-retinoblastoma
#9
Puran Fadakar, Abolfazl Akbari, Fariba Ghassemi, Gholam Reza Mobini, Masoumeh Mohebi, Manzar Bolhassani, Hoda Abed Khojasteh, Mansour Heidari
Retinoblastoma is the most common intraocular tumor in children resulting from genetic alterations and transformation of mature retinal cells. The objective of this study was to investigate the effects of SD-208, TGF-β-RI kinase inhibitor, on the expression of some miRNAs including a miR-17/92 cluster in retinoblastoma cells. Prior to initiate this work, the cell proliferation was studied by Methyl Thiazolyl Tetrazolium (MTT) and bromo-2'-deoxyuridine (BrdU) assays. Then, the expression patterns of four miRNAs (18a, 20a, 22, and 34a) were investigated in the treated SD-208 (0...
June 2016: Acta Medica Iranica
https://www.readbyqxmd.com/read/27051486/predictive-value-of-pupillary-response-to-mydriatic-agents-for-diagnosis-of-retinopathy-of-prematurity
#10
Ramak Roohipoor, Mohammad Riazi-Esfahani, Nazanin Ebrahimiadib, Reza Karkhaneh, Mohammad Zarei, Sara Besharat, Fariba Ghassemi, Mohammad Reza Ostovaneh
PURPOSE: To evaluate the feasibility of screening for retinopathy of prematurity (ROP) by assessing the pupillary response to mydriatics. METHODS: This observational case series included 134 eyes of 67 premature infants with birth weight less than 2,000 grams and gestational age less than 33 weeks. A composite eye drop composed of phenylephrine 1%, tetracaine and tropicamide 0.5% was applied 3 times within 5-minute intervals and pupil diameters were measured. The eyes were examined by experienced ROP specialists using an indirect ophthalmoscope...
October 2015: Journal of Ophthalmic & Vision Research
https://www.readbyqxmd.com/read/27046456/choroidal-thickness-changes-in-proliferative-diabetic-retinopathy-treated-with-panretinal-photocoagulation-versus-panretinal-photocoagulation-with-intravitreal-bevacizumab
#11
RANDOMIZED CONTROLLED TRIAL
Ramak Roohipoor, Elaheh Sharifian, Fariba Ghassemi, Mohammad Riazi-Esfahani, Reza Karkhaneh, Masoud Aghsaei Fard, Mohammad Zarei, Bobeck S Modjtahedi, Sasan Moghimi
PURPOSE: To compare choroidal thickness (CT) and retinal thickness (RT) between eyes with proliferative diabetic retinopathy treated with panretinal photocoagulation (PRP) or PRP with intravitreal bevacizumab (PRP + IVB). METHODS: Thirty-three patients with proliferative diabetic retinopathy were randomized to have one eye treated with PRP and the other with PRP + IVB. Change in CT was compared with baseline using enhanced depth imaging-optical coherence tomography at baseline and Months 1, 3, 6, and 10 after treatment...
October 2016: Retina
https://www.readbyqxmd.com/read/27009449/efficacy-of-intravitreal-bevacizumab-for-zone-ii-retinopathy-of-prematurity
#12
RANDOMIZED CONTROLLED TRIAL
Reza Karkhaneh, Alireza Khodabande, Mohammad Riazi-Eafahani, Ramak Roohipoor, Fariba Ghassemi, Marjan Imani, Afsar Dastjani Farahani, Nazanin Ebrahimi Adib, Hamidreza Torabi
PURPOSE: To assess the effect of intravitreal bevacizumab for Type 1 retinopathy of prematurity (ROP) in zone II ROP. METHODS: We conducted a randomized clinical trial. Preterm infants with a gestational age less than 34 weeks or birthweight less than 2000 g were examined at 4 weeks chronological age or 31 weeks postmenstrual age (whichever was later). Preterm infants with Zone-II/Stage 2 or 3 and plus disease were included. Eligible infants were randomized to receive either conventional indirect laser therapy or intravitreal bevacizumab injections (0...
September 2016: Acta Ophthalmologica
https://www.readbyqxmd.com/read/26089630/risk-definition-and-management-strategies-in-retinoblastoma-current-perspectives
#13
REVIEW
Fariba Ghassemi, Alireza Khodabande
This manuscript focuses on high-risk factors of metastatic disease in retinoblastoma and evaluation of the current treatments of retinoblastoma. Presence of histopathologic high-risk factors is associated with a higher risk of local recurrence and systemic metastasis. Currently, globe-sparing therapies, including systemic chemotherapy, intra-arterial chemoreduction, intravitreal chemotherapy, focal consolidation, and combination therapies, are being used and investigated actively. Major advances are being made in the diagnosis and management of retinoblastoma that will lead to improved morbidity and mortality rates in patients with retinoblastoma...
2015: Clinical Ophthalmology
https://www.readbyqxmd.com/read/26005559/resolution-of-primary-acquired-melanosis-with-atypia-after-treatment-with-topical-mitomycin-c-and-interferon-alfa-2b
#14
Fariba Ghassemi, Hadi Ghadimi, Mojgan Nikdel
PURPOSE: To report a case of primary acquired melanosis (PAM) successfully treated with combined topical mitomycin C and interferon-α2b. CASE REPORT: A 75-year-old man presented with an extensive unilateral pigmented lesion involving 360° of the bulbar conjunctiva, extending to the fornices and palpebral conjunctiva. Map biopsy confirmed PAM with local atypia. Treatment was initiated with mitomycin C 0.04% eye drops for two courses. Although the lesion markedly responded to the treatment, residual lesions justified further therapy...
January 2015: Journal of Ophthalmic & Vision Research
https://www.readbyqxmd.com/read/25763076/outcome-of-retinoblastoma-following-limited-sessions-of-intra-arterial-chemotherapy-in-iran
#15
Fariba Ghassemi, Hossein Ghanaati, Reza Karkhaneh, Leila Boujabadi, Seied Zia Tabatabaie, Mohammad Taher Rajabi
BACKGROUND: The management of retinoblastoma remains a challenge to the multidisciplinary team, particularly as treatment affects not only visual outcomes, but also ocular retention and morbidity. Management of retinoblastoma has evolved over the past two decades. OBJECTIVES: To report the result of intra-ophthalmic artery chemotherapy (IAC) for the treatment of refractory and advanced retinoblastoma tumors. PATIENTS AND METHODS: All patients who had failed to respond adequately to previous treatments and six naive patients with advanced retinoblastoma, receiving IAC between 2009 and 2012, were included in this institutional interventional case series...
August 2014: Iranian Journal of Radiology: a Quarterly Journal Published By the Iranian Radiological Society
https://www.readbyqxmd.com/read/25667742/retinoblastoma-in-adults-a-case-report-and-literature-review
#16
Mehdi Sharifzadeh, Fariba Ghassemi, Fahimeh Asadi Amoli, Elham Rahmanikhah, Seid Zia Tabatabaie
PURPOSE: To report a case of adult retinoblastoma with a wrong diagnosis of melanoma. CASE REPORT: Herein, we present an adult retinoblastoma case who was misdiagnosed as melanoma in fine-needle aspiration biopsy with intravitreal hemorrhage and later neovascular glaucoma after biopsy. The diagnosis of retinoblastoma was confirmed after enucleation. CONCLUSION: Retinoblastoma should be considered in the differential diagnosis of an intraocular mass in adults, especially when media haziness precludes adequate ophthalmoscopic visualization...
July 2014: Journal of Ophthalmic & Vision Research
https://www.readbyqxmd.com/read/25390665/retinoblastoma-in-oculocutaneous-albinism
#17
Fariba Ghassemi, Carol L Shields, Cesare Pirondini, Ralph C Eagle, Jerry A Shields
PURPOSE: To report a case of retinoblastoma in a child with oculocutaneous albinism (OCA). METHODS: A 24-month-old girl with classic features of OCA developed leukocoria in the left eye. RESULTS: The patient was found to have an endophytic retinoblastoma and an exophytic retinoblastoma, with a total retinal detachment and neovascularization of the iris. Enucle-ation was performed, and histopathology confirmed massive retinoblastoma with optic nerve involvement to the posterior margin of the lamina cribrosa but no choroidal invasion...
2010: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/25279120/characteristics-of-germline-and-non-germline-retinoblastomas
#18
Fariba Ghassemi, Hormoz Chams, Siamak Sabour, Reza Karkhaneh, Farzad Farzbod, Mehdi Khodaparast, Parvaneh Vosough
PURPOSE: To discuss the clinical characteristics, treatment and outcomes of germline and non-germline retinoblastoma tumors. METHODS: A retrospective study was performed on retinoblastoma cases from 1979 to 2007. General characteristics of the patients, treatment modalities, histopathological findings and survival were compared in germline versus non-germline cases. RESULTS: We analyzed 557 cases of retinoblastoma with mean age of 32.2±22...
April 2014: Journal of Ophthalmic & Vision Research
https://www.readbyqxmd.com/read/25103660/spontaneous-closure-of-traumatic-macular-holes
#19
Hooshang Faghihi, Fariba Ghassemi, Khalil Ghasemi Falavarjani, Ghasem Saeedi Anari, Mona Safizadeh, Kourosh Shahraki
OBJECTIVE: To present a series of cases with spontaneous closure of traumatic macular hole. DESIGN: Case series. PARTICIPANTS: Six eyes of 6 patients with traumatic macular hole. METHODS: The characteristics of eyes with macular hole secondary to blunt trauma in which the macular hole closed spontaneously without surgical manipulation were reviewed. RESULTS: Patient age range was 13 to 55 years...
August 2014: Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie
https://www.readbyqxmd.com/read/24982732/pseudomelanoma-at-a-referral-center-in-iran
#20
Fariba Ghassemi, Fatemeh Bazvand, Seyedeh Simindokht Hosseini
PURPOSE: To report the diagnoses of lesions initially misdiagnosed as ocular melanoma. METHODS: This retrospective study included all new patients who were referred with a presumptive diagnosis of choroidal melanoma to the ocular oncology clinic at Farabi Eye Hospital from January 2009 to December 2012. Each patient underwent a full ocular examination and B-scan ultrasonography by an ocular oncologist. The final diagnosis was made based on a combination of clinical features, fluorescein angiography, indocyanine green angiography, optical coherence tomography, neuroimaging and biopsy when necessary...
January 2014: Journal of Ophthalmic & Vision Research
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