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https://www.readbyqxmd.com/read/28335517/state-of-the-art-on-functional-virgin-olive-oils-enriched-with-bioactive-compounds-and-their-properties
#1
REVIEW
Patricia Reboredo-Rodríguez, María Figueiredo-González, Carmen González-Barreiro, Jesús Simal-Gándara, María Desamparados Salvador, Beatriz Cancho-Grande, Giuseppe Fregapane
Virgin olive oil, the main fat of the Mediterranean diet, is per se considered as a functional food-as stated by the European Food Safety Authority (EFSA)-due to its content in healthy compounds. The daily intake of endogenous bioactive phenolics from virgin olive oil is variable due to the influence of multiple agronomic and technological factors. Thus, a good strategy to ensure an optimal intake of polyphenols through habitual diet would be to produce enriched virgin olive oil with well-known bioactive polyphenols...
March 20, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28330231/prevalence-of-toxigenic-fungi-in-common-medicinal-herbs-and-spices-in-india
#2
Visenuo Aiko, Alka Mehta
Mycotoxins are unavoidable contaminants of food grains, feeds, medicinal herbs, and spices, posing as health threat to animals and humans. The objective of this study was to screen medicinal herbs and spices for fungi and mycotoxin contamination and evaluate their safety. Sixty-three samples were examined for fungal contamination and fungal load determined using standard microbiological method. Aflatoxin and citrinin were detected using thin layer chromatography and high-performance chromatography technique...
December 2016: 3 Biotech
https://www.readbyqxmd.com/read/28326452/methyleugenol-dna-adducts-in-human-liver-are-associated-with-sult1a1-copy-number-variations-and-expression-levels
#3
Roman Tremmel, Kristin Herrmann, Wolfram Engst, Walter Meinl, Kathrin Klein, Hansruedi Glatt, Ulrich M Zanger
Methyleugenol is a rodent hepatocarcinogen occurring in many herbs and spices as well as essential oils used for flavoring. Following metabolic activation by cytochromes P450 (CYPs) and sulfotransferases (SULTs), methyleugenol can form DNA adducts. Previously, we showed that DNA adduct formation by methyleugenol in mouse liver is dependent on SULT1A1 expression and that methyleugenol DNA adducts are abundant in human liver specimens. In humans, SULT1A1 activity is affected by genetic polymorphisms, including single-nucleotide polymorphisms (SNPs) and copy number variations (CNVs)...
March 22, 2017: Archives of Toxicology
https://www.readbyqxmd.com/read/28326446/blastocystis-how-do-specific-diets-and-human-gut-microbiota-affect-its-development-and-pathogenicity
#4
REVIEW
M Lepczyńska, J Białkowska, E Dzika, K Piskorz-Ogórek, J Korycińska
Blastocystis is an enteric parasite that inhabits the gastrointestinal tract of humans and many animals. This emerging parasite has a worldwide distribution. It is often identified as the most common eukaryotic organism reported in human fecal samples. This parasite is recognized and diagnosed more often than ever before. Furthermore, some strains develop resistance against currently recommended drugs, such as metronidazole; therefore, the use of natural remedies or special diets has many positive aspects that may address this problem...
March 22, 2017: European Journal of Clinical Microbiology & Infectious Diseases
https://www.readbyqxmd.com/read/28300025/evaluation-of-matrix-effects-in-multiresidue-analysis-of-pesticide-residues-in-vegetables-and-spices-by-lc-ms-ms
#5
Suchi Chawla, Hemlatta K Patel, Hetal N Gor, Kiran M Vaghela, Priti P Solanki, Paresh G Shah
The study was conducted to investigate matrix interferences using QuEChERS sample preparation to understand whether thedilution of matrix and/or the grouping of commodities can eliminate the need for selective individual matrix-matched standards in LC with tandem MS (MS/MS) analysis, and whether the calibration graph based on only one matrix can be used for quantification in the other matrixes. Matrix effects (MEs) were studied by comparing the slopes of calibration curves of the matrix-matched standards (diluted with mobile phase) vis-à-vis the solvent-based standards...
March 16, 2017: Journal of AOAC International
https://www.readbyqxmd.com/read/28298686/chemical-composition-and-biological-properties-of-satureja-avromanica-maroofi
#6
Elham Abdali, Shima Javadi, Maryam Akhgari, Seyran Hosseini, Dara Dastan
Satureja avromanica is an indigenous plant which is frequently used as a spice in Avraman-Kurdistan region of Iran. The present study aimed to investigate the chemical composition, antimicrobial and antioxidant properties of the S. avromanica. In addition, rosmarinic acid and total phenolic content of S. avromanica was assessed by spectrophotometric method and HPTLC. The essential oil and methanolic extract were isolated by hydrodistillation and maceration methods, respectively. A total of 32 compounds representing 98...
March 2017: Journal of Food Science and Technology
https://www.readbyqxmd.com/read/28291912/improving-the-efficiency-of-breast-radiotherapy-treatment-planning-using-a-semi-automated-approach
#7
Robert A Mitchell, Philip Wai, Ruth Colgan, Anna M Kirby, Ellen M Donovan
OBJECTIVES: To reduce treatment planning times while maintaining plan quality through the introduction of semi-automated planning techniques for breast radiotherapy. METHODS: Automatic critical structure delineation was examined using the Smart Probabilistic Image Contouring Engine (SPICE) commercial autosegmentation software (Philips Radiation Oncology Systems, Fitchburg, WI) for a cohort of ten patients. Semiautomated planning was investigated by employing scripting in the treatment planning system to automate segment creation for breast step-and-shoot planning and create objectives for segment weight optimization; considerations were made for three different multileaf collimator (MLC) configurations...
January 2017: Journal of Applied Clinical Medical Physics
https://www.readbyqxmd.com/read/28275734/decoupling-biogeochemical-records-extinction-and-environmental-change-during-the-cambrian-spice-event
#8
James D Schiffbauer, John Warren Huntley, David A Fike, Matthew Jarrell Jeffrey, Jay M Gregg, Kevin L Shelton
Several positive carbon isotope excursions in Lower Paleozoic rocks, including the prominent Upper Cambrian Steptoean Positive Carbon Isotope Excursion (SPICE), are thought to reflect intermittent perturbations in the hydrosphere-biosphere system. Models explaining these secular changes are abundant, but the synchronicity and regional variation of the isotope signals are not well understood. Examination of cores across a paleodepth gradient in the Upper Cambrian central Missouri intrashelf basin (United States) reveals a time-transgressive, facies-dependent nature of the SPICE...
March 2017: Science Advances
https://www.readbyqxmd.com/read/28274615/oxidative-metabolism-of-curcumin-glucuronide-by-peroxidases-and-isolated-human-leukocytes
#9
Paula B Luis, Odaine N Gordon, Fumie Nakashima, Akil I Joseph, Takahiro Shibata, Koji Uchida, Claus Schneider
Conjugation with glucuronic acid is a prevalent metabolic pathway of orally administrated curcumin, the bioactive diphenol of the spice turmeric. The major in vitro degradation reaction of curcumin is autoxidative transformation resulting in oxygenation and cyclization of the heptadienedione chain to form cyclopentadione derivatives. Here we show that curcumin-glucuronide is much more stable than curcumin, degrading about two orders of magnitude slower. Horseradish peroxidase-catalyzed oxidation of curcumin-glucuronide occurred at about 80% of the rate with curcumin, achieving efficient transformation...
March 6, 2017: Biochemical Pharmacology
https://www.readbyqxmd.com/read/28267599/the-rna-binding-protein-serbp1-interacts-selectively-with-the-signaling-protein-rack1
#10
Graeme B Bolger
The RACK1 protein interacts with numerous proteins involved in signal transduction, the cytoskeleton, and mRNA splicing and translation. We used the 2-hybrid system to identify additional proteins interacting with RACK1 and isolated the RNA-binding protein SERBP1. SERPB1 shares amino acid sequence homology with HABP4 (also known as Ki-1/57), a component of the RNA spicing machinery that has been shown previously to interact with RACK1. Several different isoforms of SERBP1, generated by alternative mRNA splicing, interacted with RACK1 with indistinguishable interaction strength, as determined by a 2-hybrid beta-galactosidase assay...
March 4, 2017: Cellular Signalling
https://www.readbyqxmd.com/read/28267416/posttranscriptional-mechanisms-controlling-diurnal-gene-expression-cycles-by-body-temperature-rhythms
#11
Ivana Gotic, Ueli Schibler
In mammals, body temperature oscillates in a daily fashion around a set point of 36°C-37°C. These fluctuations are controlled by the circadian master clock residing in the brain's suprachiasmatic nucleus and, despite their small amplitudes, contribute to the diurnal expression of genes throughout the organism. By focusing on the mechanisms underlying the temperature-dependent accumulation of the cold-inducible RNA-binding protein CIRBP - a factor involved in the tuning of amplitude and phase in circadian clocks of peripheral tissues - we have recently identified a novel mechanism governing temperature-dependent gene expression...
March 2, 2017: RNA Biology
https://www.readbyqxmd.com/read/28266134/a-small-plant-with-big-benefits-fenugreek-trigonella-foenum-graecum-linn-for-disease-prevention-and-health-promotion
#12
REVIEW
Kalyan C Nagulapalli Venkata, Debasis Bagchi, Anupam Bishayee
Plant-derived natural products have long-standing utility towards treating degenerative diseases. It is estimated that about two-third of world population depend on traditional medicine for primary medical needs. Fenugreek (Trigonella foenum-graecum Linn.), a short-living annual medicinal plant belonging to Fabaceae family, is used extensively in various parts of the world as herb, food, spice and traditional medicine. Fenugreek is considered as one of the oldest medicinal plants and its health-promoting effects have been cited in Ayurveda and traditional Chinese medicine...
March 7, 2017: Molecular Nutrition & Food Research
https://www.readbyqxmd.com/read/28263006/rapid-analysis-of-forensic-related-samples-using-two-ambient-ionization-techniques-coupled-to-high-resolution-mass-spectrometers
#13
Eshwar Jagerdeo, Amanda Wriston
RATIONALE: This paper highlights the versatility of interfacing two ambient ionization techniques, Laser Diode Thermal Desorption (LDTD) and Atmospheric Solids Analysis probe (ASAP), to high resolution mass spectrometers and demonstrate the method's capability to rapidly generate high-quality data from multiple sample types with minimal, if any sample preparation. METHODS: For ASAP-MS analysis of solid and liquid samples, the material was transferred to a capillary surface before being introduced into the mass spectrometer...
March 6, 2017: Rapid Communications in Mass Spectrometry: RCM
https://www.readbyqxmd.com/read/28262132/ischemic-stroke-associated-with-the-use-of-a-synthetic-cannabinoid-spice
#14
Sebastian Moeller, Caroline Lücke, Tobias Struffert, Bernhard Schwarze, Stefan T Gerner, Stefan Schwab, Martin Köhrmann, Kristin Machold, Alexandra Philipsen, Helge H Müller
Synthetic cannabinoids, i.e. "spice", are psychoactive drugs with increasing use worldwide. Spice may have harmful neuropsychiatric and physical side effects. Here, we present the case of a 25-year-old man with ischemic stroke after smoking spice on the previous evening. Diagnostic work-up was negative for other common causes of stroke. Toxicology screen unveiled the cannabimimetic ADB-FUBINACA in the drug sample and in patient's urine. The cardiac sympathomimetic effect of spice might have triggered an unnoticed episode of tachyarrhythmia and resulted in stroke via cardioembolic etiology...
February 2017: Asian Journal of Psychiatry
https://www.readbyqxmd.com/read/28257977/review-of-antidiabetic-fruits-vegetables-beverages-oils-and-spices-commonly-consumed-in-the-diet
#15
REVIEW
Maliheh Najari Beidokhti, Anna K Jäger
ETHNOPHARMACOLOGICAL RELEVANCE: Type 2 diabetes is the most common type of diabetes and its prevalence is rapidly increasing throughout the world. Modifications of lifestyle such as suitable diet and exercise programs along with pharmacotherapy and education of patients are beneficial therapies for patients with type 2 diabetes. The ethnopharmacological use of herbal medicines, many of them part of our diet as spices, vegetables and fruits, has been developed for the treatment of diabetes due to inexpensiveness, easy availability and few side effects...
February 28, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/28254575/in-vivo-cough-suppressive-activity-of-pectic-polysaccharide-with-arabinogalactan-type-ii-side-chains-of-piper-nigrum-fruits-and-its-synergistic-effect-with-piperine
#16
Sadhana Khawas, Gabriela Nosáľová, Sujay Kumar Majee, Kanika Ghosh, Washim Raja, Veronika Sivová, Bimalendu Ray
Piper nigrum L. fruits are not only a prized spice, but also highly valued therapeutic agent that heals many ailments including asthma, cold and respiratory problems. Herein, we have investigated structural features and in vivo antitussive activity of three fractions isolated from Piper nigrum fruits. The water extract (PN-WE) upon fractionation with EtOH yielded two fractions: a soluble fraction (PN-eSf) and a precipitated (PN-ePf) one. The existence of a pectic polysaccharide with arabinogalactan type II side chains (147kDa) in PN-ePf and piperine in PN-eSf were revealed...
February 28, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28251112/in-vitro-anticancer-activity-of-ethanolic-extracts-of-piper-nigrum-against-colorectal-carcinoma-cell-lines
#17
Akila Prashant, Chandini Rangaswamy, Anshu Kumar Yadav, Varun Reddy, M N Sowmya, Subbarao Madhunapantula
BACKGROUND: Piper nigrum (PN) is well known for its cytotoxic and pharmacological benefits. However, there is minimal documented evidence about its cytotoxic efficacy against colorectal carcinoma. We therefore sought to procure a precisely quantitative and qualitative result, pertaining the efficacy of an ethanolic extract of PN (EEPN) against colorectal carcinoma. MATERIALS AND METHODS: EEPN was prepared by subjecting dried PN seeds to gradient ethanol fractionation...
January 2017: International Journal of Applied and Basic Medical Research
https://www.readbyqxmd.com/read/28250905/possible-role-of-common-spices-as-a-preventive-and-therapeutic-agent-for-alzheimer-s-disease
#18
REVIEW
Omid Mirmosayyeb, Amirpouya Tanhaei, Hamid R Sohrabi, Ralph N Martins, Mana Tanhaei, Mohammad Amin Najafi, Ali Safaei, Rokhsareh Meamar
For centuries, spices have been consumed as food additives or medicinal agents. However, there is increasing evidence indicating the plant-based foods in regular diet may lower the risk of neurodegenerative diseases including Alzheimer disease. Spices, as one of the most commonly used plant-based food additives may provide more than just flavors, but as agents that may prevent or even halt neurodegenerative processes associated with aging. In this article, we review the role and application of five commonly used dietary spices including saffron turmeric, pepper family, zingiber, and cinnamon...
2017: International Journal of Preventive Medicine
https://www.readbyqxmd.com/read/28249302/which-bay-leaf-is-in-your-spice-rack-a-quality-control-study
#19
Vijayasankar Raman, Rainer W Bussmann, Ikhlas A Khan
The accurate identification of bay leaf in natural products commerce may often be confusing as the name is applied to several different species of aromatic plants. The true "bay leaf", also known as "bay laurel" or "sweet bay", is sourced from the tree Laurus nobilis, a native of the Mediterranean region. Nevertheless, the leaves of several other species including Cinnamomum tamala, Litsea glaucescens, Pimenta racemosa, Syzygium polyanthum, and Umbellularia californica are commonly substituted or mistaken for true bay leaves due to their similarity in the leaf morphology, aroma, and flavor...
March 1, 2017: Planta Medica
https://www.readbyqxmd.com/read/28238395/profound-hypotension-and-bradycardia-in-the-setting-of-synthetic-cannabinoid-intoxication-a-case-series
#20
David O Andonian, Shauna R Seaman, Elaine B Josephson
Cannabinoids are the most commonly used illegal substances in the world [1]. Synthetic Cannabinoids (SCB) are also known as "Spice", "K2", "Spike", "herbal incense", "Cloud 9", "Mojo" and many others are becoming a large public health concern due to their increasing use, unpredictable toxicity, and abuse potential [2]. The most common reported toxicities with SCB use based on studies using Texas Poison control record are tachycardia, agitation and irritability, drowsiness, hallucinations, delusions, hypertension, nausea, confusion, dizziness, vertigo, chest pain, acute kidney injury, seizures, heart attacks and both ischemic and hemorrhagic strokes [3]...
January 12, 2017: American Journal of Emergency Medicine
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