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Lilian H D van Tuyl, Martina Sadlonova, Sarah Hewlett, Bev Davis, Caroline Flurey, Niti Goel, Laure Gossec, Cecilie Heegaard Brahe, Catherine L Hill, Wijnanda Hoogland, John Kirwan, Merete L Hetland, Dirkjan van Schaardenburg, Josef S Smolen, Tanja Stamm, Marieke Voshaar, George A Wells, Maarten Boers
BACKGROUND: Guidelines suggest treatment in rheumatoid arthritis (RA) to target remission, in close consultation with the patient. Our recent qualitative study of the patients' perspective on remission in RA identified 26 domains. The current study aimed to identify a short list of the most important aspects to inform future research. METHODS: Patients with RA from the Netherlands, the UK, Austria, Denmark, France and the USA completed a survey that contained all domains identified in our qualitative study...
November 30, 2016: Annals of the Rheumatic Diseases
Rana Alsilani, Fatima Jadu, Dania F Bogari, Ahmed M Jan, Turki Y Alhazzazi
The introduction of single-file nickel-titanium (NiTi) reciprocating systems has been a major breakthrough in the field of endodontics. Thus, the aim of this study was to compare the available reciprocating systems, Reciproc and WaveOne, using a meta-analysis with different parameters. A comprehensive electronic literature search for Reciproc and WaveOne using PubMed and Google scholar was initially conducted in September 2014 and updated in September 2016. Inclusion and exclusion criteria were then established...
September 2016: Journal of International Society of Preventive & Community Dentistry
Corneliu Crăciunescu, Aurel Ercuta
The effect of superposed transitions in actuators with layered shape memory alloy (SMA) films undergoing martensitic phase transformation is analyzed in terms of a model developed for two layers of different composition, deposited at the same temperature on a substrate. A significant difference is observed in the actuation versus temperature relationship, depending on the thermal and elastic properties of the SMA layers and their martensitic transformation temperature. The prediction of the actuation is exemplified using a multilayer model and is verified for a cantilever actuator with NiTi and NiMnGa layers deposited on a Si substrate...
December 2015: Science and Technology of Advanced Materials
Dongmian Zang, Hui Yi, Zhandong Gu, Lie Chen, Dong Han, Xinglin Guo, Shutao Wang, Mingjie Liu, Lei Jiang
Seamlessly bridging the hard and the soft, a strategy to fabricate hierarchically porous NiTi/hydrogels nanocomposites is reported herein. The nanocomposite surface can hold high-content water while keeping its hierarchical nanoscale topography, thus showing exceptional antibiofouling performance. This strategy will lead to antibiofouling alloy (e.g., NiTi)/hydrogel nanocomposites for improved stents and other blood-contacting implants and medical devices.
November 10, 2016: Advanced Materials
Xiaofeng Shi, Jichun Yang, Xiongying Cui, Jiansong Huang, Zhangbiao Long, Yulan Zhou, Ping Liu, Lanlan Tao, Zheng Ruan, Bing Xiao, Wei Zhang, Dongya Li, Kesheng Dai, Jianhua Mao, Xiaodong Xi
Previous studies in Chinese hamster ovary cells showed that truncational mutations of β3 at sites of F754 and Y759 mimicking calpain cleavage regulate integrin signaling. The roles of the sequence from F754 to C-terminus and the conservative N756ITY759 motif in platelet function have yet to be elaborated. Mice expressing β3 with F754 and Y759 truncations, or NITY deletion (β3-ΔTNITYRGT, β3-ΔRGT, or β3-ΔNITY) were established through transplanting the homozygous β3-deficient mouse bone marrow cells infected by the GFP tagged MSCV MigR1 retroviral vector encoding different β3 mutants into lethally radiated wild-type mice...
2016: PloS One
Kirubaharan S Abraham, Nithya Jagdish, Vignesh Kailasam, Sridevi Padmanabhan
OBJECTIVES: To compare the adhesion of Streptococcus mutans to nickel titanium (NiTi) and copper-NiTi (Cu-NiTi) archwires and to correlate the adhesion to surface characteristics (surface free energy and surface roughness) of these wires. MATERIALS AND METHODS: A total of 16 patients undergoing orthodontic treatment with preadjusted edgewise appliances were included in the study. 0.016" and 0.016" × 0.022" NiTi and Cu-NiTi archwires in as-received condition and after 4 weeks of intraoral use were studied for S mutans adhesion using real-time polymerase chain reaction...
November 16, 2016: Angle Orthodontist
Jung-Hong Ha, Sang Won Kwak, Sung-Kyo Kim, Hyeon-Cheol Kim
OBJECTIVES: The purpose of this study was to compare the maximum screw-in forces generated during the movement of various Nickel-Titanium (NiTi) file systems. MATERIALS AND METHODS: Forty simulated canals in resin blocks were randomly divided into 4 groups for the following instruments: Mtwo size 25/0.07 (MTW, VDW GmbH), Reciproc R25 (RPR, VDW GmbH), ProTaper Universal F2 (PTU, Dentsply Maillefer), and ProTaper Next X2 (PTN, Dentsply Maillefer, n = 10). All the artificial canals were prepared to obtain a standardized lumen by using ProTaper Universal F1...
November 2016: Restorative Dentistry & Endodontics
Christoph Bechtold, Rodrigo Lima de Miranda, Christoph Chluba, Eckhard Quandt
Self-expandable medical devices provide mechanical functionality at a specific location of the human body and are viable for minimal invasive procedures. Besides radiopaque markers and drug-eluting coatings, next generation self-expandable devices can be equipped with additional functionality, such as conductive and flexible electrodes, which enables chronic recording of bioelectrical signals, stimulating or ablating tissue. This promises new therapeutic options in various medical fields, among them in particular neuromodulation (e...
December 2016: Biomedical Microdevices
Venith Jojee Pulikkottil, S Chidambaram, P U Bejoy, P K Femin, Parson Paul, Mohamed Rishad
OBJECTIVE: (1) To evaluate the corrosion resistance of four different orthodontic archwires and to determine the effect of 0.5% NaF (simulating high fluoride-containing toothpaste of about 2250 ppm) on corrosion resistance of these archwires. (2) To assess whether surface roughness (Ra) is the primary factor influencing the corrosion resistance of these archwires. MATERIALS AND METHODS: Four different archwires (stainless steel [SS], nickel-titanium [NiTi], titanium molybdenum alloy [TMA], and ion-implanted TMA) were considered for this study...
October 2016: Journal of Pharmacy & Bioallied Sciences
D Nagarajan, Balashanmugam Baskaranarayanan, K Usha, M S Jayanthi, M Vijjaykanth
INTRODUCTION: The application of light and continuous forces for optimum physiological response and the least damage to the tooth supporting structures should be the primary aim of an orthodontist. Nickel-titanium (NiTi) alloys with their desirable properties are one of the natural choices of the clinicians. AIM: This study was aimed to compare and rank them based on its tensile strength and electrical resistivity. MATERIALS AND METHODS: The sample consisted of eight groups of 0...
October 2016: Journal of Pharmacy & Bioallied Sciences
Sara Anvari, Niti Y Chokshi, Qurat Ul Ain Kamili, Carla McGuire Davis
Importance: The reported prevalence of peanut allergy among children in the United States has increased more than 3-fold in the last 20 years. Medical guidelines on the introduction of peanut as well as other allergenic foods have evolved with the emerging evidence that an early introduction to these foods is more beneficial than a delayed introduction. This review highlights the studies that have led to the evolving guidelines on peanut introduction in infants. Observations: The prevalence of peanut allergy has increased despite the publication of guidelines from the American Academy of Pediatrics in 2000, which recommended a delayed introduction of peanut...
November 7, 2016: JAMA Pediatrics
Niti Ngamsomprasert, Gautam Panda, Shuhei Higashibayashi, Hidehiro Sakurai
Hydroxysumanene was synthesized from acylsumanenes by Baeyer-Villiger oxidation. DFT calculation predicted the higher bowl inversion energy and deeper bowl structure of hydroxysumanene than those of pristine sumanene. The bowl inversion energy of hydroxysumanene was experimentally determined by 2D-EXSY NMR measurement as 21.2 kcal/mol. The energy was larger than that of pristine sumanene (20.3 kcal/mol), which agreed with the calculation result. Electrochemical measurement indicated the higher HOMO level of hydroxysumanene than that of sumanene, which confirmed the electron-rich character of the phenolic function in the bowl skeleton...
November 3, 2016: Journal of Organic Chemistry
S Bürklein, P G Jäger, E Schäfer
AIM: To compare the apical transportation and the canal straightening of three continuous tapered rotary NiTi systems (F6 SkyTaper (Komet/Brasseler, Lemgo, Germany), Mtwo (VDW, Munich, Germany), OneShape (Micro Méga, Besançon France)) in severely curved root canals. METHODOLOGY: A total of 60 root canals in extracted human teeth with angles of curvatures ranging between 25° and 35° and radii ranging between 4 and 9mm were divided into three groups (n=20). Based on radiographs taken prior to instrumentation, the groups were balanced with respect to the angle and the radius of canal curvature (P=1...
November 3, 2016: International Endodontic Journal
Ozge Erken Gungor, Alper Kustarci
PURPOSE: The aim of this study was to compare the effects of 2 NiTi file systems [Twisted File Adaptive (TFA) and Reciproc (RP)] and 2 irrigation techniques [Conventional needle irrigation (CNI) and Laser activated irrigation (LAI)] on the amount of apically extruded debris in primary maxillary molars. STUDY DESIGN: Sixty extracted primary maxillary molars were randomly divided into 4 groups. The mesio-buccal roots of teeth in 4 groups were instrumented using TFA with LAI, RP with LAI, TFA with CNI and RP with CNI respectively...
2016: Journal of Clinical Pediatric Dentistry
Indu Biswal, Rajni Gaind, Neeraj Kumar, Srujana Mohanty, Vikas Manchanda, Niti Khunger, Ramesh V, Monorama Deb
INTRODUCTION: Propionibacterium acnes has been implicated in the development of acne vulgaris. Rampant use of topical and systemic antibiotics for acne vulgaris has led to resistance due to selective pressure. This study aimed to determine antibiotic resistance of P. acnes. METHODOLOGY: A total of 102 samples were collected from acne lesions and cultured onto sheep's blood agar and brain-heart infusion agar supplemented with 5 g/L glucose and 2 mg/L furazolidone) (BHIg) under aerobic and anaerobic conditions...
October 31, 2016: Journal of Infection in Developing Countries
Vahid Zand, Amin Salem Milani, Ayla Hassani Dehkharghani, Mahdi Rahbar, Pardis Tehranchi
INTRODUCTION: One of the most important reasons for postoperative pain is the extrusion of debris from the apical foramen during preparation and shaping of root canals. The aim of this clinical trial was to evaluate the severity of postoperative pain with the use of two different engine-driven NiTi systems. METHODS AND MATERIALS: Ninety mandibular molars were randomly divided into two groups (n=45), and root canal cleaning and shaping was done using either RaCe or Reciproc instruments...
2016: Iranian Endodontic Journal
Deeksha Bhartiya, Vandna Chawla, Sourav Ghosh, Ravi Shankar, Niti Kumar
The AT-rich genome of P. falciparum has uniquely localized G-rich stretches that have propensity to form G-quadruplexes. However, their global occurrence and potential biological roles in the parasite are poorly explored. Our genome-wide analysis revealed unique enrichment of quadruplexes in P. falciparum genome which was remarkably different from other Plasmodium species. A distinct predominance of quadruplexes was observed in nuclear and organellar genes that participate in antigenic variation, pathogenesis, DNA/RNA regulation, metabolic and protein quality control processes...
October 24, 2016: Genomics
Alberto Dagna, Giulia Gastaldo, Riccardo Beltrami, Claudio Poggio
This study evaluated the root canal dentine surface by scanning electron microscope (SEM) after shaping with two reciprocating single-file NiTi systems and two rotating single-file NiTi systems, in order to verify the presence/absence of the smear layer and the presence/absence of open tubules along the walls of each sample; Forty-eight single-rooted teeth were divided into four groups and shaped with OneShape (OS), F6 SkyTaper (F6), WaveOne (WO) and Reciproc and irrigated using 5.25% NaOCl and 17% EDTA. Root canal walls were analyzed by SEM at a standard magnification of 2500×...
October 17, 2016: Journal of Functional Biomaterials
Huma D Hussain, Sreedevi D Ajith, Prachi Goel
AIMS: This study was conducted to evaluate and compare the nickel release from stainless steel and nickel titanium archwires in artificial saliva over three months with the use of simulated fixed orthodontic appliances. METHODS AND MATERIALS: Fifty simulated fixed orthodontic appliances representing half of the dental arch were used for this study. Five groups of ten samples each were made. Group A was the control group without archwires. Groups B and C contained stainless steel archwires from American Orthodontics (Sheboygan, WI, USA) and Dentaurum (Remanium, Ispringen, Germany) respectively...
September 2016: Journal of Oral Biology and Craniofacial Research
Fibin Thanveer, Niti Khunger
CONTEXT: A distressing pre-occupation with an imagined or slight defect in appearance with a marked negative effect on the patient's life is the core symptom of body dysmorphic disorder (BDD). AIM: To screen the patients attending a dermatology clinic at a tertiary care centre for BDD using the BDD-dermatology version (DV) questionnaire. SETTINGS AND DESIGN: This cross-sectional study enrolled 245 consecutive patients from the dermatology outpatients clinic...
July 2016: Journal of Cutaneous and Aesthetic Surgery
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