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Alberto Dagna, Giulia Gastaldo, Riccardo Beltrami, Claudio Poggio
This study evaluated the root canal dentine surface by scanning electron microscope (SEM) after shaping with two reciprocating single-file NiTi systems and two rotating single-file NiTi systems, in order to verify the presence/absence of the smear layer and the presence/absence of open tubules along the walls of each sample; Forty-eight single-rooted teeth were divided into four groups and shaped with OneShape (OS), F6 SkyTaper (F6), WaveOne (WO) and Reciproc and irrigated using 5.25% NaOCl and 17% EDTA. Root canal walls were analyzed by SEM at a standard magnification of 2500×...
October 17, 2016: Journal of Functional Biomaterials
Huma D Hussain, Sreedevi D Ajith, Prachi Goel
AIMS: This study was conducted to evaluate and compare the nickel release from stainless steel and nickel titanium archwires in artificial saliva over three months with the use of simulated fixed orthodontic appliances. METHODS AND MATERIALS: Fifty simulated fixed orthodontic appliances representing half of the dental arch were used for this study. Five groups of ten samples each were made. Group A was the control group without archwires. Groups B and C contained stainless steel archwires from American Orthodontics (Sheboygan, WI, USA) and Dentaurum (Remanium, Ispringen, Germany) respectively...
September 2016: Journal of Oral Biology and Craniofacial Research
Fibin Thanveer, Niti Khunger
CONTEXT: A distressing pre-occupation with an imagined or slight defect in appearance with a marked negative effect on the patient's life is the core symptom of body dysmorphic disorder (BDD). AIM: To screen the patients attending a dermatology clinic at a tertiary care centre for BDD using the BDD-dermatology version (DV) questionnaire. SETTINGS AND DESIGN: This cross-sectional study enrolled 245 consecutive patients from the dermatology outpatients clinic...
July 2016: Journal of Cutaneous and Aesthetic Surgery
Niti Khunger
No abstract text is available yet for this article.
July 2016: Journal of Cutaneous and Aesthetic Surgery
Louise Klokker, Peter Tugwell, Daniel E Furst, Dan Devoe, Paula Williamson, Caroline B Terwee, Maria E Suarez-Almazor, Vibeke Strand, Thasia Woodworth, Amye L Leong, Niti Goel, Maarten Boers, Peter M Brooks, Lee S Simon, Robin Christensen
OBJECTIVE: Failure to report harmful outcomes in clinical research can introduce bias favoring a potentially harmful intervention. While core outcome sets (COS) are available for benefits in randomized controlled trials in many rheumatic conditions, less attention has been paid to safety in such COS. The Outcome Measures in Rheumatology (OMERACT) Filter 2.0 emphasizes the importance of measuring harms. The Safety Working Group was reestablished at the OMERACT 2016 with the objective to develop a COS for assessing safety components in trials across rheumatologic conditions...
October 15, 2016: Journal of Rheumatology
Mirella Luciani, Gisella Armillotta, Laura Manna, Antonella Ciarelli, Tiziana Di Febo, Ivanka Krasteva, Attilio Pini, Flavio Sacchini, Anna Rita D'Angelo
An immunohistochemical (IHC) technique was optimised using a monoclonal antibody (MAb) to detect Mycoplasma mycoides subsp. mycoides (Mmm), the agent of Contagious Bovine Pleuropneumonia (CBPP), in sections of lung tissue. A panel of MAbs was produced and screened for Mmm speci city and for cross-reactivity against other mycoplasmas belonging and not belonging to the Mycoplasma mycoides cluster, using in parallel indirect ELISA (i-ELISA) and Immunoblotting (IB). Based on i-ELISA and IB characterization data, 1 MAb (clone 3G10E7) was selected and its highest a nity vs Mmm was con rmed by the Quartz Crystal Microbalance (QCM) technology...
July 15, 2016: Veterinaria Italiana
I Kaşikçi Bilgi, I Köseler, P Güneri, M Hülsmann, M K Çalişkan
AIM: To compare the amount of apically extruded debris and of remaining filling material during the removal of root canal filling material using three rotary NiTi retreatment instruments or Hedström files. METHODOLOGY: Ninety-six severely curved human molars of both jaws were selected. The root canals were prepared to size X2 (tip size 25, .06 taper) using the ProTaper Next system (Dentsply Sirona, Ballaigues, Switzerland), filled with gutta-percha and AH Plus sealer (Dentsply De Trey, Konstanz, Germany) and were randomly divided into 4 experimental groups (n= 24 each) with two subgroups of maxillary and mandibular teeth each...
October 5, 2016: International Endodontic Journal
Juan-Gonzalo Olivier, Marc García-Font, Jose-Antonio Gonzalez-Sanchez, Miguel Roig-Cayon, Fernando Durán-Sindreu
BACKGROUND: The objective of the study was to evaluate and compare how apical enlargement with K3 and K3XF nickel-titanium (NiTi) rotary instruments reduces the root thickness in the danger zone and affects canal transportation and centering ability in mandibular molar mesial canals in a manikin extracted tooth model. MATERIAL AND METHODS: Seventy-two mesial root canals of first mandibular molars were instrumented. Initial and post-instrumentation Cone Beam Computed Tomography scans were performed after root canal preparation up to size 25, 30, 35 and 40 files...
October 2016: Journal of Clinical and Experimental Dentistry
F Ferreira, I Barbosa, P Scelza, D Russano, J Neff, M Montagnana, M Zaccaro Scelza
AIM: To describe a new method for the assessment of nanoscale alterations in the surface topography of nickel-titanium endodontic instruments using a high-resolution optical method, and to verify the accuracy of the technique. METHODOLOGY: Noncontact three-dimensional optical profilometry was used to evaluate defects on a size 25, .08 taper reciprocating instrument (WaveOne(®) ), which was subjected to a cyclic fatigue test in a simulated root canal in a clear resin block...
October 1, 2016: International Endodontic Journal
Madhusudana Pulaganti, Anuradha C M, Chitta Suresh Kumar
Pseudomonas aeruginosa (P.aeruginosa) is an opportunistic microorganism causing diseases both in animals and humans. In case of human pathology, the role of P.aeruginosa is one of the major concerns in intensive care septicemia. Presently the drug resistance strains of P.aeruginosa are arising mainly by developing multiple mechanisms due to its natural and acquired resistance to many of the antimicrobial agents commonly used in clinical practice. As a result, there is a direneed to invent new drugs so that they may restrict the outbreak of multidrug resistant strains...
August 15, 2016: Journal of Biomolecular Structure & Dynamics
Zeiad Hussain, Athanasios Diamantopoulos, Miltiadis Krokidis, Konstantinos Katsanos
AIM: To investigate the efficacy of double-layered covered stent in the treatment of malignant oesophageal obstructions. METHODS: A systematic review and meta-analysis was performed following the PRISMA process. PubMed (Medline), EMBASE (Excerpta Medical Database), AMED (Allied and Complementary medicine Database), Scopus and online content, were searched for studies reporting on the NiTi-S polyurethane-covered double oesophageal stent for the treatment of malignant dysphagia...
September 14, 2016: World Journal of Gastroenterology: WJG
Maryam Iman, Zeynab Khansepid, Asghar Davood
BACKGROUND: Ribonucleotide Reductase (RNR) is an important anticancer chemotherapy target. It has main key role in DNA synthesis and cell growth. Therefore several RNR inhibitors, such as Hydroxyurea, have entered the clinical trials. Based on our proposed mechanism, radical site of RNR protein reacts with Hydroxyurea in which hydroxyurea is converted into its oxidized form compound III, and whereby the tyrosyl radical is converted into a normal tyrosine residue. OBJECTIVE: In this study, docking and molecular dynamics simulations were used for proposed molecular mechanism of Hydroxyurea in RNR inhibition as anticancer agent...
September 26, 2016: Recent Patents on Anti-cancer Drug Discovery
Huiju Wang, Wenlan Song, Min Zhang, Qi Zhen, Mei Guo, Yida Zhang, Xinzhen Du
A novel titanium and nickel oxide composite nanosheets (TiO2/NiOCNSs) coating was in situ grown on a Nitinol (NiTi) wire by direct hydrothermal treatment and modified by self-assembly of trichlorophenylsilane for solid phase microextraction (SPME). TiO2/NiOCNSs were radially oriented and chemically bonded to the NiTi substrate with double-faced open access sites. Moreover the phenyl modified TiO2/NiOCNSs (TiO2/NiOCNSs-Ph) coating exhibited original surface supporting framework favorable for effective SPME. The extraction performance of TiO2/NiOCNSs-Ph coated NiTi (NiTi-TiO2/NiOCNSs-Ph) fiber was investigated for the concentration and detection of ultraviolet (UV) filters, polycyclic aromatic hydrocarbons (PAHs), phthalate acid esters and polychlorinated biphenyls coupled to HPLC with UV detection...
October 14, 2016: Journal of Chromatography. A
Gustavo De-Deus, Felipe Gonçalves Belladonna, Erick Miranda Souza, Vanessa de Oliveira Alves, Emmanuel João Nogueira Leal Silva, Evaldo Rodrigues, Marco Aurélio Versiani, Carlos Eduardo da Silveira Bueno
INTRODUCTION: Glide path preparation has been recommended as a mandatory clinical step to ensure the safe usage of nickel-titanium (NiTi) rotary instruments. This study aimed to evaluate the effectiveness and fracture rate of 4 pathfinding NiTi rotary instruments in mechanically negotiating moderately curved molar canals. METHODS: Moderately curved maxillary (n = 120) and mandibular (n = 120) molars were randomly distributed into 4 experimental groups (n = 60, 30 maxillary and 30 mandibular molars) according to the instrument used for glide path preparation: ScoutRace 10/...
October 2016: Journal of Endodontics
P Saumya-Rajesh, J Krithikadatta, N Velmurugan, C Sooriaprakas
AIM: This randomized controlled trial compared the incidence of post-instrumentation pain associated with Mtwo rotary NiTi files and the self-adjusting file system following canal shaping and cleaning. METHODOLOGY: Following sample size estimation, a total of 130 patients were randomized into two groups based on selection criteria [group Mtwo and group SAF (self-adjusting file)]. Root canal treatment was carried out in two appointments. The teeth were endodontically treated with the appropriate allotted systems following the similar clinical parameters...
September 23, 2016: International Endodontic Journal
Danyal A Siddiqui, Shiril Sivan, Jason D Weaver, Matthew Di Prima
Metallic medical devices such as intravascular stents can undergo fretting damage in vivo that might increase their susceptibility to pitting corrosion. As a result, the US Food and Drug Administration has recommended that such devices be evaluated for corrosion resistance after the devices have been fatigue tested in situations where significant micromotion can lead to fretting damage. Three common alloys that cardiovascular implants are made from [MP35N cobalt chromium (MP35N), electropolished nitinol (EP NiTi), and 316LVM stainless steel (316LVM)] were selected for this study...
September 23, 2016: Journal of Biomedical Materials Research. Part B, Applied Biomaterials
Venkata Naidu Bavikati, Gowri Sankar Singaraju, Prasad Mandava, Sai Sandeep Killamsetty, Venkatesh Nettam, Praveen Kumar Reddy Karnati
INTRODUCTION: The initial leveling and aligning phase has been simplified with the introduction of superelastic nickel-titanium archwires. The relatively high cost of these wires has prompted some of the clinicians to reuse them after sterilization. The quantitative changes in the surface properties of superelastic 'NiTi' wires after clinical application and recycling by autoclave method have not been established in earlier studies. AIM: To quantify the changes in mechanical and physical properties of four different commercially available superelastic nitinol (NiTi) archwires after clinical usage and recycling...
July 2016: Journal of Clinical and Diagnostic Research: JCDR
Mojgan Kachoei, Azin Nourian, Baharak Divband, Zahra Kachoei, Sajjad Shirazi
AIM: To fabricate a friction-reducing and antibacterial coating with zinc oxide (ZnO) nanoparticles on nickel-titanium (NiTi) wire. MATERIALS & METHODS: NiTi orthodontic wires were coated with ZnO nanoparticles using the chemical deposition method. Characteristics of the coating as well as the physical, mechanical and antibacterial properties of the wires were investigated. RESULTS: A stable and well-adhered ZnO coating on the NiTi wires was obtained...
October 2016: Nanomedicine
Ana-Maria Orbai, Maarten de Wit, Philip Mease, Judy A Shea, Laure Gossec, Ying Ying Leung, William Tillett, Musaab Elmamoun, Kristina Callis Duffin, Willemina Campbell, Robin Christensen, Laura Coates, Emma Dures, Lihi Eder, Oliver FitzGerald, Dafna Gladman, Niti Goel, Suzanne Dolwick Grieb, Sarah Hewlett, Pil Hoejgaard, Umut Kalyoncu, Chris Lindsay, Neil McHugh, Bev Shea, Ingrid Steinkoenig, Vibeke Strand, Alexis Ogdie
OBJECTIVE: To identify a core set of domains (outcomes) to be measured in psoriatic arthritis (PsA) clinical trials that represent both patients' and physicians' priorities. METHODS: We conducted (1) a systematic literature review (SLR) of domains assessed in PsA; (2) international focus groups to identify domains important to people with PsA; (3) two international surveys with patients and physicians to prioritise domains; (4) an international face-to-face meeting with patients and physicians using the nominal group technique method to agree on the most important domains; and (5) presentation and votes at the Outcome Measures in Rheumatology (OMERACT) conference in May 2016...
September 9, 2016: Annals of the Rheumatic Diseases
Sarah Shizuko Morimoto, Faith M Gunning, Bruce E Wexler, Willie Hu, Irena Ilieva, Jiacheng Liu, Juliana Nitis, George S Alexopoulos
OBJECTIVES: Executive dysfunction (ED) is a predictor of poor treatment response of late-life depression to pharmacotherapy. In response to the consistency of these findings, we designed neuroplasticity-based computerized cognitive remediation (nCCR-GD) intervention to target and improve ED in patients who failed to remit with antidepressant treatment. This study tests the hypothesis that ED at baseline will predict favorable treatment response to nCCR-GD. METHODS: 11 elderly patients with treatment-resistant major depression were treated with a 30-hour, 4-week, unblinded, nCCR-GD treatment trial...
October 2016: American Journal of Geriatric Psychiatry
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