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https://www.readbyqxmd.com/read/29907567/ras-signaling-activates-glycosylphosphatidylinositol-anchor-biosynthesis-via-the-gpi-n-acetylglucosaminyl-transferase-gpi-gnt-in-candida-albicans
#1
Priyanka Jain, Subhash Chandra Sethi, Vavilala A Pratyusha, Pramita Garai, Nilofer Naqvi, Sonali Singh, Kalpana Pawar, Niti Puri, Sneha Sudha Komath
The ability of C. albicans to switch between yeast to hyphal form is a property that is primarily associated with the invasion and virulence of this human pathogenic fungus. Several GPI anchored proteins are expressed only during hyphal morphogenesis. One of the major pathways that controls hyphal morphogenesis is the Ras signaling pathway. We examine the cross-talk between GPI anchor biosynthesis and Ras signaling in C. albicans We show that the first step of GPI biosynthesis is activated by Ras in C. albicans This is diametrically opposite to what is reported in S...
June 15, 2018: Journal of Biological Chemistry
https://www.readbyqxmd.com/read/29895994/pitfalls-in-ultrasound-diagnosis-of-cesarean-scar-pregnancy
#2
REVIEW
Lakshmy Ravi Selvaraj, Nity Rose, Meenakshi Ramachandran
Cesarean scar pregnancy (CSP) is a rare kind of ectopic pregnancy implanted in the previous cesarean scar and has an increasing incidence over the past 30 years. As the suspicion is low, the diagnosis may be delayed or misinterpreted in ultrasound, leading to treatment strategies that might end up in uterine rupture or hysterectomy. The objective here is to review the ultrasound findings in CSP with varied presentations. Transabdominal and transvaginal sonography combined with color Doppler is a reliable tool for the diagnosis of CSP...
June 2018: Journal of Obstetrics and Gynaecology of India
https://www.readbyqxmd.com/read/29890266/niti-nb-micro-trusses-fabricated-via-extrusion-based-3d-printing-of-powders-and-transient-liquid-phase-sintering
#3
Shannon L Taylor, Amaka J Ibeh, Adam E Jakus, Ramille N Shah, David C Dunand
We present a novel additive manufacturing method for NiTi-Nb micro-trusses combining (i) extrusion-based 3D-printing of liquid inks containing NiTi and Nb powders, solvents, and a polymer binder into micro-trusses with 0/90° ABAB layers of parallel, ∼600 µm struts spaced 1 mm apart and (ii) subsequent heat-treatment to remove the binder and solvents, and then bond the NiTi powders using liquid phase sintering via the formation of a transient NiTi-Nb eutectic phase. We investigate the effects of Nb concentration (0, 1...
June 8, 2018: Acta Biomaterialia
https://www.readbyqxmd.com/read/29872237/corrosion-of-nickel-titanium-orthodontic-archwires-in-saliva-and-oral-probiotic-supplements
#4
Ines Musa Trolić, Gianluca Turco, Luca Contardo, Nikolina Leona Serdarević, Helena Otmačić, Ćurković, Stjepan Špalj
Objectives: The aim of the study was to examine how probiotic supplements affect the corrosion stability of orthodontic archwires made of nickel-titanium alloy (NiTi). Materials and Methods: NiTi archwires (0.508x0.508 and having the length of 2.5 cm) were tested. The archwires (composition Ni=50.4%, Ti=49.6%) were uncoated, nitrified and rhodium coated. Surface microgeometry was observed by using scanning electron microscope and surface roughness was measured by profilometer through these variables: roughness average, maximum height and maximum roughness depth...
December 2017: Acta Stomatologica Croatica
https://www.readbyqxmd.com/read/29861728/comparative-evaluation-of-root-canal-transportation-by-three-niti-single-file-systems-in-curved-canals-a-cone-beam-computed-tomography-study
#5
Eshaghali Saberi, Narges Farhad-Mollashahi, Shima Bijari, Mohammad Daryaeian
Introduction: This study is aimed at evaluating root canal transportation in the mesiobuccal canal of mandibular first molars prepared with One Shape, Reciproc, and M-One nickel titanium (NiTi) single-file rotary systems using cone beam computed tomography (CBCT). Materials and Methods: In this ex vivo study, CBCT scans of 45 extracted human mandibular first molars with 20-40° curvature were obtained. The teeth were randomly divided into three groups ( n =15) for preparation of the mesiobuccal canal with One Shape, Reciproc, and M-One rotary systems according to the manufacturers' instructions...
2018: International Journal of Dentistry
https://www.readbyqxmd.com/read/29861643/an-in-vivo-comparison-of-accuracy-of-two-electronic-apex-locators-in-determining-working-length-using-stainless-steel-and-nickel-titanium-files
#6
Sanjeeb Chaudhary, Archana Gharti, Bhawana Adhikari
Purpose: A key factor affecting the success of endodontic treatment is correct determination of root canal working length (WL). The purpose of this in vivo study was to compare the accuracy of Propex II and iPex II electronic apex locator (EAL) in determining the WL under clinical conditions, to that of radiographic working length (RWL) using stainless steel (SS) and nickel-titanium (NiTi) hand files. Patients and methods: Thirty-seven patients, with 60 anterior teeth (60 canals) scheduled for endodontic treatment participated in this study after ethical approval...
2018: Clinical, Cosmetic and Investigational Dentistry
https://www.readbyqxmd.com/read/29858500/shaping-ability-of-biorace-protaper-next-and-genius-nickel-titanium-instruments-in-curved-canals-of-mandibular-molars-a-micro-ct-study
#7
S Drukteinis, V Peciuliene, P M H Dummer, J Hupp
AIM: To evaluate and compare the canal shaping ability of BioRace, ProTaper NEXT, and Genius engine driven nickel-titanium (NiTi) file systems in extracted mandibular first molars using micro-computed tomography (MCT). METHODOLOGY: Sixty mesial root canals of mandibular first molars were randomly divided into three equal groups, according to the instrument system used for root canal preparation (n=20): BioRace (BR), ProTaper NEXT (PTN), or Genius (GN). Root canals were prepared to the full WL using a crown-down technique up to size 35, ...
June 1, 2018: International Endodontic Journal
https://www.readbyqxmd.com/read/29858356/the-patient-research-partner-network-matures-a-report-from-the-grappa-2017-annual-meeting
#8
Niti Goel, Denis O'Sullivan, Maarten de Wit, Chris A Lindsay, Heidi Bertheussen, John Latella, Jeffrey Chau, Roland MacDonald, Suzanne Grieb, Ingrid Steinkoenig, Willemina Campbell
The Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA) has reached the third of 5 stages of organizational maturity regarding incorporating patient research partners (PRP) into psoriatic arthritis (PsA) and psoriasis research and educational efforts. Herein, we report the involvement of PRP at the GRAPPA 2017 annual meeting and plans for future PRP engagement.
June 2018: Journal of Rheumatology. Supplement
https://www.readbyqxmd.com/read/29858348/content-and-face-validity-and-feasibility-of-5-candidate-instruments-for-psoriatic-arthritis-randomized-controlled-trials-the-psa-omeract-core-set-workshop-at-the-grappa-2017-annual-meeting
#9
Richard Holland, William Tillett, Alexis Ogdie, Ying Y Leung, Dafna D Gladman, Kristina Callis Duffin, Laura C Coates, Philip J Mease, Lihi Eder, Vibeke Strand, Musaab Elmamoun, Pil Højgaard, Jeffrey Chau, Maarten de Wit, Niti Goel, Chris A Lindsay, Oliver FitzGerald, Bev Shea, Dorcas Beaton, Ana-Maria Orbai
The Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA)-Outcome Measures in Rheumatology (OMERACT) Psoriatic Arthritis (PsA) Core Set working group is in the process of selecting core instruments for PsA clinical trials. During a 2-h workshop and breakout group discussions at the GRAPPA 2017 annual meeting in Amsterdam, the Netherlands, participants discussed the first set of candidate instruments to be taken through the OMERACT Filter 2.1 instrument selection process: 66/68 swollen/tender joint count (66/68JC), Spondyloarthritis Consortium of Canada (SPARCC) enthesitis index, patient's global assessment (GRAPPA and OMERACT formulations), Health Assessment Questionnaire-Disability Index (HAQ-DI), Psoriatic Arthritis Impact of Disease (PsAID) questionnaires 9 and 12, and Functional Assessment of Chronic Illness Therapy (FACIT) Fatigue...
June 2018: Journal of Rheumatology. Supplement
https://www.readbyqxmd.com/read/29803163/fabrication-of-bio-inspired-nitinol-alloy-surface-with-tunable-anisotropic-wetting-and-high-adhesive-ability
#10
Yan L Tian, Yue C Zhao, Cheng J Yang, Fu J Wang, Xian P Liu, Xiu B Jing
In this paper, micro/nano-scale structures were fabricated on nitinol alloy (NiTi) to realize tunable anisotropic wetting and high adhesive capability. Laser texturing and silanization process are utilized to change the morphological and chemical properties of substrates. It is noted that these treated substrates exhibit the joint characteristics of anisotropic wetting and high adhesive capability. In order to investigate the influences of laser-texturing and silanization processes on NiTi, these surfaces were evaluated using scanning electron microscope (SEM), a white light confocal microscope, X-ray photoelectron spectroscopy (XPS) and goniometer...
May 16, 2018: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/29800602/a-novel-signal-sequence-negative-multimeric-glycosomal-protein-required-for-cell-cycle-progression-of-leishmania-donovani-parasites
#11
Kavita Ahuja, Mirza Adil Beg, Ruby Sharma, Ajay Saxena, Nilofer Naqvi, Niti Puri, Pradeep Kumar Rai, Ashok Chaudhury, Robert Duncan, Poonam Salotra, Hira Nakhasi, Angamuthu Selvapandiyan
Expression of the intracellular form amastigote specific genes in the Leishmania donovani parasite plays a major role in parasite replication in the macrophage. In the current work, we have characterized a novel hypothetical gene, Ld30b that is specifically transcribed in the intracellular stage of the parasite. The recombinant Ld30b protein exists as a pentamer in solution as identified by native-PAGE and size exclusion gel chromatography. Structural analysis using circular dichroism and molecular modeling indicate that Ld30b belongs to family of cAMP-dependent protein kinase type I-alpha regulatory subunit...
May 22, 2018: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/29788716/porous-silsesquioxane-imine-frameworks-as-highly-e%C3%AF-cient-adsorbents-for-cooperative-iodine-capture
#12
Mateusz Janeta, Wojciech Bury, Slawomir Szafert
The efficient capture and storage of radioactive iodine (129 I or 131 I), which can be formed during nuclear energy generation or storage of nuclear waste, is of paramount importance. Herein we present highly efficient aerogels for reversible iodine capture, namely Porous Silsesquioxane-Imine Frameworks (PSIF), constructed by a condensation of octa(3-aminopropyl)silsesquioxane cage compound (OAS-POSS) and selected multitopic aldehydes. The resulting PSIFs are permanently porous (Brunauer-Emmet-Teller (BET) surface areas up to 574 m2 /g), thermally stable and present a combination of micro-, meso- and macropores in their structures...
May 23, 2018: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29766447/optimizing-radionuclide-protocols-dotting-our-i-s-and-crossing-our-t-s
#13
EDITORIAL
Niti R Aggarwal
No abstract text is available yet for this article.
May 15, 2018: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/29765904/cyclic-fatigue-resistance-torsional-resistance-and-metallurgical-characteristics-of-m3-rotary-and-m3-pro-gold-niti-files
#14
Eugenio Pedullà, Fabio Lo Savio, Giusy Rita Maria La Rosa, Gabriele Miccoli, Elena Bruno, Silvia Rapisarda, Seok Woo Chang, Ernesto Rapisarda, Guido La Rosa, Gianluca Gambarini, Luca Testarelli
Objectives: To evaluate the mechanical properties and metallurgical characteristics of the M3 Rotary and M3 Pro Gold files (United Dental). Materials and Methods: One hundred and sixty new M3 Rotary and M3 Pro Gold files (sizes 20/0.04 and 25/0.04) were used. Torque and angle of rotation at failure ( n = 20) were measured according to ISO 3630-1. Cyclic fatigue resistance was tested by measuring the number of cycles to failure in an artificial stainless steel canal (60° angle of curvature and a 5-mm radius)...
May 2018: Restorative Dentistry & Endodontics
https://www.readbyqxmd.com/read/29763971/evaluation-of-the-effects-of-the-solution-used-for-electrochemical-dissolution-of-nickel-titanium-endodontic-files-on-dentine-structure-microhardness-and-cell-viability
#15
C C F Amaral, F Ormiga, L C Boldrini, P G Miranda, T A Mendonça, J M Granjeiro, J A C P Gomes
AIM: To evaluate the effects of the [NaF 12 g/L + NaCl 1 g/L] solution used in the electrochemical dissolution process of fractured endodontic files, as well as its NiTi-containing product, on dentine hardness, topography and human fibroblast viability. METHODOLOGY: Sixty single-rooted human teeth were evaluated for dentine microhardness using the Vickers hardness test and the area and number of dentinal tubules by scanning electron microscopy. The samples were divided according to the dentine surface treatment: distilled water; 17% EDTA; [NaF 12 g/L + NaCl 1 g/L]; and 17% EDTA + [NaF 12 g/L + NaCl 1 g/L]...
May 15, 2018: International Endodontic Journal
https://www.readbyqxmd.com/read/29756274/niti-loss-on-the-dentinal-walls-and-instrument-deformation-during-root-canal-preparation
#16
Carolina Fabiana Centenaro, Fabiana Soares Grecca, Patrícia Maria Poli Kopper, Rodrigo Ricci Vivan, Jefferson Ricardo Pereira, Ricardo Abreu da Rosa, Paula Barcellos da Silva, Marcus Vinícius Reis Só
The purpose of this study was to quantify the presence of nickel (Ni) and titanium (Ti) on dentin walls of prepared root canals using Endosequence (ES) and Wave One (WO) systems, the deformation, and fracture of these instruments. Thirty extracted human premolar teeth were selected and prepared with WO, ES, and manually (control group-CG). Each instrument was used in four root canals. The root canals were irrigated with 2.5% sodium hypochlorite solution. After preparation, roots were sectioned longitudinally and the apical third was analyzed by scanning electron microscopy with X-ray microanalysis (SEM-EDS)...
May 13, 2018: Microscopy Research and Technique
https://www.readbyqxmd.com/read/29752078/length-dependent-corrosion-behavior-ni-2-release-cytocompatibility-and-antibacterial-ability-of-ni-ti-o-nanopores-anodically-grown-on-biomedical-niti-alloy
#17
Ruiqiang Hang, Yanlian Liu, Long Bai, Xiangyu Zhang, Xiaobo Huang, Husheng Jia, Bin Tang
In the present work, nickel-titanium-oxygen nanopores with different length (0.55-114 μm) were anodically grown on nearly equiatomic nickel-titanium (NiTi) alloy. Length-dependent corrosion behavior, nickel ion (Ni2+ ) release, cytocompatibility, and antibacterial ability were investigated by electrochemical, analytical chemistry, and biological methods. The results show constructing nanoporous structure on the NiTi alloy improve its corrosion resistance. However, the anodized samples release more Ni2+ than that of the bare NiTi alloy, suggesting chemical dissolution of the nanopores rather than electrochemical corrosion governs the Ni2+ release...
August 1, 2018: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/29735855/mandibular-dental-arch-changes-with-active-self-ligating-brackets-combined-with-different-archwires
#18
E Atik, B Akarsu-Guven, I Kocadereli
Objective: The aim was to compare mandibular arch and incisor inclinational changes by comparing active self-ligating brackets used with different forms of archwires with a control group in nonextraction cases. Materials and Methods: The sample of 50 patients with Class I malocclusion was divided into three groups: Group I was treated with active self-ligating brackets (Nexus, Ormco/Orange, CA, USA) used with Damon arch form copper nickel-titanium (Cu-NiTi) and stainless steel (SS) wires; Group II was treated with interactive self-ligating bracket system (Empower, American Orthodontics, Sheboygan, Wis, USA) used with standard Cu-NiTi and SS wires; and Group III was treated with Roth prescribed conventional brackets (Forestadent, Pforzheim, Germany) with standard Cu-NiTi and SS wires which was designed as a control group...
May 2018: Nigerian Journal of Clinical Practice
https://www.readbyqxmd.com/read/29732301/evaluation-of-the-alignment-efficiency-of-nickel-titanium-and-copper-nickel-titanium-archwires-in-patients-undergoing-orthodontic-treatment-over-a-12-week-period-a-single-center-randomized-controlled-clinical-trial
#19
Burcu Aydın, Neslihan Ebru Şenışık, Özgür Koşkan
Objective: The aim of this trial was to compare the alignment efficiency and intermaxillary arch dimension changes of nickel-titanium (NiTi) or copper-nickel-titanium (CuNiTi) round archwires with increasing diameters applied sequentially to the mandibular arch. Methods: The initial alignment phase of fixed orthodontic treatment with NiTi or CuNiTi round archwires was studied in a randomly allocated sample of 66 patients. The NiTi group comprised 26 women, 10 men, and the CuNiTi (27℃) group comprised 20 women, 10 men...
May 2018: Korean Journal of Orthodontics
https://www.readbyqxmd.com/read/29729042/transgastric-reintervention-for-self-expandable-metallic-stent-dysfunction-following-eus-guided-hepaticogastrostomy
#20
Tesshin Ban, Hiroshi Kawakami, Yoshimasa Kubota
EUS-guided hepaticogastrostomy (EUS-HGS) using a self-expandable metallic stent (SEMS) is recognized as an alternative to transpapillary access for performing biliary drainage.1,2 However, reintervention to mitigate stent dysfunction remains challenging.3-5 Here, we present a case of successful transgastric exchange of occluded SEMS. A 53-year-old woman with pancreatic cancer was admitted with acute cholangitis. Five months before, she underwent EUS-HGS using partially covered SEMS (6 mm×12 cm Niti-STM S Biliary Stent; Taewoong Medical Co...
May 5, 2018: Digestive Endoscopy: Official Journal of the Japan Gastroenterological Endoscopy Society
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